Hyperhomocysteinemia

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56 Substances Researched for Hyperhomocysteinemia
NameACCKFocus
Vitamin B-1228249Locked
Folic Acid 19151Locked
Vitamin B-613133Locked
B-complex661Locked
Vitamin D431Locked
5-Methyltetrahydrofolate (MTHF)330Locked
Omega-3 Fatty Acids220Locked
Vitamin B12120Locked
Vitamin E220Locked
Allicin110Locked
Antioxidant formulas110Locked
Blue-Green Algae110Locked
Carotenoids110Locked
Fiber110Locked
Fish Oil110Locked
Folate: Dietary110Locked
Garlic110Locked
Honey110Locked
Oats110Locked
Pycnogenol (Pine Bark)110Locked
Thiamine (B-1) 110Locked
Vitamin C110Locked
beta-Carotene110Locked
Curcumin58Locked
Astaxanthin37Locked
Arginine24Locked
Astragalus24Locked
Folate13Locked
Polyphenols23Locked
Beer12Locked
Berberine12Locked
Betaine 12Locked
Creatine12Locked
Embelia ribes12Locked
Emodin12Locked
Fisetin12Locked
Ginsenosides12Locked
Histidine12Locked
Melatonin12Locked
Methionine12Locked
Nigella sativa (aka Black Seed)12Locked
Quercetin12Locked
Red Wine Extract12Locked
Resveratrol22Locked
Safflower12Locked
Thymoquinone12Locked
Flavonoids11Locked
Ginseng, unspecified species11Locked
Goji11Locked
Hydroxytyrosol11Locked
Isoflavones11Locked
Naringenin 11Locked
Tanshinone IIA11Locked
Tetrahydrocurcumin11Locked
Vitamin B12: methylcobalamin 11Locked
Choline10Locked
3 Problem Substances Researched for Hyperhomocysteinemia
NameACCKFocus
Oral Contraceptives120Locked
Lead110Locked
Metformin 110Locked
3 Therapeutic Actions Researched for Hyperhomocysteinemia
NameACCKFocus
Dietary Modification: Vegetarian220Locked
Yoga110Locked
Dietary Modification: Mediterranean Diet11Locked

View the Evidence:
110 Abstracts with Hyperhomocysteinemia Research

[+]

Folic aicd combined with vitamin B6 and B12 treatment significantly reduced plasma homocysteine levelMay 31, 2015

Pubmed Data : Zhonghua Xin Xue Guan Bing Za Zhi. 2015 Jun ;43(6):554-61. PMID: 26420127
Article Published Date : May 31, 2015
Study Type : Meta Analysis
Additional Links
Substances : Folic Acid , Vitamin B-12, Vitamin B-6
Diseases : Cardiovascular Diseases, High Homocysteine
Additional Keywords : Risk Factors
[+]

Serum homocysteine levels were higher and vitamin B12 levels were lower among individuals with systemic lupus erythematosus.Jul 22, 2020

Pubmed Data : J Am Coll Nutr. 2020 Jul 23:1-11. Epub 2020 Jul 23. PMID: 32702250
Article Published Date : Jul 22, 2020
Study Type : Meta Analysis
Additional Links
Substances : Vitamin B12
Diseases : Homocysteine: Elevated, Lupus Erythematosus: Systemic, Vitamin B 12 Deficiency
Additional Keywords : Risk Factors
[+]

Vitamin B supplementation was effective in reducing serum homocysteine levels.Dec 31, 2016

Pubmed Data : J Geriatr Psychiatry Neurol. 2017 Jan ;30(1):50-59. Epub 2016 Oct 17. PMID: 28248558
Article Published Date : Dec 31, 2016
Study Type : Meta Analysis
Additional Links
Substances : Folic Acid , Vitamin B-12, Vitamin B-6
Diseases : High Homocysteine
[+]

We concluded that OC users, and patients with factor V Leiden, the prothrombin G20 120A mutation, and hyperhomocysteinemia are at a significantly increased risk of cerebral vein thrombosis.Apr 01, 2006

Pubmed Data : Blood. 2006 Apr 1;107(7):2766-73. Epub 2006 Jan 5. PMID: 16397131
Article Published Date : Apr 01, 2006
Study Type : Meta Analysis
Additional Links
Diseases : Deep Vein Thrombosis, Hyperhomocysteinemia, Thrombosis
Additional Keywords : Diseases that are Linked
Problem Substances : Oral Contraceptives
[+]

The consumption of omega-3 fatty acid supplements decreases homocysteine levels in diabetic patients.Jun 01, 2010

Pubmed Data : Nutr Metab Cardiovasc Dis. 2010 Jun;20(5):326-31. Epub 2009 Jun 21. PMID: 19540739
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2, Homocysteine: Elevated
[+]

5-MTHF administration improves endothelial dysfunction in patients undergoing peritoneal dialysis. Nov 01, 2007

Pubmed Data : Nephrol Dial Transplant. 2007 Nov;22(11):3292-7. Epub 2007 Jun 25. PMID: 17595187
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Substances : 5-Methyltetrahydrofolate (MTHF)
Diseases : Endothelial Dysfunction, Hemodialysis, High Homocysteine, Kidney Failure: Chronic
[+]

A B vitamin formula decreases the carotid artery thickness in patients at risk for cerebral ischemia. Jul 01, 2005

Pubmed Data : Atherosclerosis. 2005 Jul;181(1):131-5. Epub 2005 Feb 16. PMID: 15939064
Article Published Date : Jul 01, 2005
Study Type : Human Study
Additional Links
Substances : B-complex
Diseases : Carotid Artery Narrowing, Hyperhomocysteinemia, Intima Media Thickening
[+]

A blue-green algae product improves vitamin B12 status and reduces homocysteine.Oct 01, 2005

Pubmed Data : Am J Clin Nutr. 2005 Oct;82(4):887-93. PMID: 20108213
Article Published Date : Oct 01, 2005
Study Type : Human Study
Additional Links
Substances : Blue-Green Algae, Vitamin B-12
Diseases : Homocysteine: Elevated, Vitamin B 12 Deficiency
Therapeutic Actions : Dietary Modification: Vegetarian
[+]

A significant proportion of psychiatric patients were found to be vitamin B12 deficient.Oct 09, 2019

Pubmed Data : Prim Care Companion CNS Disord. 2019 Oct 10 ;21(5). Epub 2019 Oct 10. PMID: 31617966
Article Published Date : Oct 09, 2019
Study Type : Human Study
Additional Links
Diseases : Homocysteine: Elevated, Psychiatric Disorders, Vitamin B 12 Deficiency
Additional Keywords : Risk Factors
[+]

Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis.Feb 28, 2013

Pubmed Data : Int J Cardiol. 2013 Mar 1. Epub 2013 Mar 1. PMID: 23453866
Article Published Date : Feb 28, 2013
Study Type : Human Study
Additional Links
Substances : Garlic
Diseases : Arterial Calcification, Coronary Artery Disease, High Homocysteine
Pharmacological Actions : Cardioprotective
[+]

Allicin improves carotid artery intima-media thickness in coronary artery disease patients with hyperhomocysteinemia.Jul 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2017 Aug ;14(2):1722-1726. Epub 2017 Jun 28. PMID: 28810641
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Substances : Allicin
Diseases : Hyperhomocysteinemia
Pharmacological Actions : Anticholesteremic Agents, Cardioprotective
[+]

Anemia in 85-year-old subjects is associated with folate deficiency and elevated homocysteine levels. Nov 10, 2008

Pubmed Data : Arch Intern Med. 2008 Nov 10;168(20):2238-44. PMID: 19001201
Article Published Date : Nov 10, 2008
Study Type : Human Study
Additional Links
Substances : Folic Acid
Diseases : Anemia, High Homocysteine
Additional Keywords : Diseases that are Linked
[+]

Atherothrombotic events in rheumatoid arthritis are predicted by homocysteine and folic acid reduces homocysteine levels.Sep 01, 2009

Pubmed Data : Clin Exp Rheumatol. 2009 Sep-Oct;27(5):822-5. PMID: 19917166
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Diseases : High Homocysteine, Rheumatoid Arthritis
[+]

B vitamins appear to slow cognitive and clinical decline in people with mild cognitive impairment, in particular in those with elevated homocysteine.Jul 21, 2011

Pubmed Data : Int J Geriatr Psychiatry. 2011 Jul 21. Epub 2011 Jul 21. PMID: 21780182
Article Published Date : Jul 21, 2011
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-12, Vitamin B-6
Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, High Homocysteine, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Blood lead was associated with increased homocysteine in a cohort of healthy premenopausal women.Aug 07, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health. 2017 Aug 8 ;16(1):84. Epub 2017 Aug 8. PMID: 28789684
Article Published Date : Aug 07, 2017
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Homocysteine: Elevated, Lead Poisoning
Problem Substances : Lead
[+]

Combined treatment with folic acid, vitamin B6, and vitamin B12 lowers homocysteine concentrations.May 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Am Heart Assoc. 2018 May 18 ;7(11). Epub 2018 May 18. PMID: 29776960
Article Published Date : May 17, 2018
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-12, Vitamin B-6
Diseases : Endothelial Dysfunction, Homocysteine: Elevated
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Daily supplementation with low-dose B vitamins plus betaine for 12 weeks effectively decreased plasma homocysteine concentrations.May 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Nutr. 2023 Jun ;62(4):1599-1610. Epub 2023 Jan 30. PMID: 36717385
Article Published Date : May 31, 2023
Study Type : Human Study
Additional Links
Substances : B-complex, Betaine , Vitamin B-12
Diseases : Hyperhomocysteinemia
[+]

Elevated homocysteine levels associated with polymyalgia rheumatica and giant cell arteritis and the corticosteroid therapy used to treat these conditions may be attenuated with vitamin B12 and folic acid. Sep 01, 2003

Pubmed Data : Rheumatology (Oxford). 2003 Sep;42(9):1055-61. Epub 2003 Apr 16. PMID: 12730520
Article Published Date : Sep 01, 2003
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-12
Diseases : Corticosteroid-Induced Toxicity, Cortisone Toxicity , Giant Cell Arteritis, Hyperhomocysteinemia, Polymyalgia Rheumatica
[+]

Elevated homocysteinemia is associated with peripheral vascular disease. Oct 01, 2007

Pubmed Data : J Cardiovasc Surg (Torino). 2007 Oct;48(5):601-5. PMID: 17989630
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Diseases : High Homocysteine, Hypertension, Peripheral Vascular Diseases
Additional Keywords : Risk Reduction
[+]

Even short-term treatment with metformin causes a decrease in serum cobalamin folic acid and increase in homocysteine.Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Endocrinol Metab. 2016 Sep-Oct;20(5):631-637. PMID: 27730072
Article Published Date : Aug 31, 2016
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Nutrient Depletion: Folate and Folic Acid, Homocysteine: Elevated
Additional Keywords : Risk Factors
Problem Substances : Metformin
[+]

Folate and vitamin B12 lower homocysteine concentrations in hemodialysis patients.Sep 01, 2009

Pubmed Data : Saudi J Kidney Dis Transpl. 2009 Sep;20(5):779-88. PMID: 19736473
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : Hemodialysis, High Homocysteine
Additional Keywords : Diseases that are Linked
[+]

Folic acid effect on homocysteine, sortilin levels and glycemic control in type 2 diabetes mellitus patients.Jan 21, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Diabetes. 2022 06 22 ;12(1):33. Epub 2022 Jun 22. PMID: 35732620
Article Published Date : Jan 21, 2022
Study Type : Human Study
Additional Links
Substances : Folic Acid
Diseases : Diabetes Mellitus: Type 2, Homocysteine: Elevated, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents
[+]

Folic acid supplementation appears to reduce homocysteine and possibly blood pressure in children. Feb 01, 2010

Pubmed Data : Int J Food Sci Nutr. 2010 Feb;61(1):11-7. PMID: 19939196
Article Published Date : Feb 01, 2010
Study Type : Human Study
Additional Links
Diseases : High Homocysteine, Hypertension
[+]

High antioxidant intake is associated with lower blood concentrations of C-reactive protein and plasma homocysteine concentrations in US adults.cMar 18, 2011

Pubmed Data : Public Health Nutr. 2011 Mar 18:1-10. Epub 2011 Mar 18. PMID: 21414247
Article Published Date : Mar 18, 2011
Study Type : Human Study
Additional Links
Substances : Antioxidant formulas, Carotenoids, Vitamin C, Vitamin E
Diseases : C-Reactive Protein, High Homocysteine
Pharmacological Actions : Cardioprotective
[+]

High homocysteine levels are associated with neurodegenerative conditions such as Parkinson's disease, ALS and progressive supranuclear palsy.Jul 01, 2010

Pubmed Data : Dement Geriatr Cogn Disord. 2010 Jul;29(6):553-9. Epub 2010 Jul 3. PMID: 20606437
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Diseases : Amyotrophic Lateral Sclerosis, Hyperhomocysteinemia, Parkinson's Disease, Supranuclear Palsy: Progressive
Additional Keywords : Diseases that are Linked
[+]

High homocysteine levels may be associated with the pathogenesis of neurological disorders.Jan 01, 2010

Pubmed Data : Front Biosci (Schol Ed). 2010;2:359-72. Epub 2010 Jan 1. PMID: 20036953
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : B-complex
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Epilepsy, High Homocysteine, Hyperhomocysteinemia, Multiple Sclerosis, Parkinson's Disease, Stroke
Additional Keywords : Diseases that are Linked
[+]

High homocysteine levels may play a role in the pathopysiology of bipolar disorder. Jan 01, 2005

Pubmed Data : Acta Vet Hung. 2005;53(3):319-24. PMID: 18579214
Article Published Date : Jan 01, 2005
Study Type : Human Study
Additional Links
Diseases : Bipolar Disorder, High Homocysteine
Additional Keywords : Diseases that are Linked
[+]

High homocysteine, low vitamin B-6, and increased oxidative stress are independently associated with the risk of chronic kidney disease.Jan 31, 2016

Pubmed Data : Nutrition. 2016 Feb ;32(2):236-41. Epub 2015 Sep 25. PMID: 26526964
Article Published Date : Jan 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin B-6
Diseases : Chronic Kidney Disease (CKD), High Homocysteine, Oxidative Stress, Vitamin B6 Depletion
Pharmacological Actions : Antioxidants
Additional Keywords : Risk Factors
[+]

High plasma homocysteine and low folate levels were observed in the patients with lung cancer compared to control group.Aug 31, 2015

Pubmed Data : Exp Oncol. 2015 Sep ;37(3):218-22. PMID: 26422108
Article Published Date : Aug 31, 2015
Study Type : Human Study
Additional Links
Substances : Folate: Dietary
Diseases : Folic Acid/Folate Deficiency, High Homocysteine, Lung Cancer, Lung Cancer: Prevention
Additional Keywords : Risk Factors
[+]

High-dose short-term folate administration modifies ambulatory blood pressure in postmenopausal women. Oct 01, 2009

Pubmed Data : Eur J Clin Nutr. 2009 Oct;63(10):1266-8. Epub 2009 Jul 15. PMID: 19603054
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : 5-Methyltetrahydrofolate (MTHF)
Diseases : Aging, Cardiovascular Diseases, High Homocysteine, Hypertension, Insulin Resistance, Metabolic Syndrome X, Postmenopausal Disorders
Pharmacological Actions : Hypotensive
[+]

Homocysteine levels in the tear fluid and plasma of patients with primary open-angle glaucoma is often elevated, indicating that inadequate vitamin b levels (e.g. b6, b12, and folate) may contribute to the disease.Jan 01, 2008

Pubmed Data : Ophthalmic Res. 2008;40(5):249-56. Epub 2008 Apr 25. PMID: 18437035
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-12, Vitamin B-6
Diseases : Glaucoma, High Homocysteine
[+]

Homocysteine levels may be elevated in obstructive sleep apnea. Sep 01, 2001

Pubmed Data : Chest. 2001 Sep;120(3):900-8. PMID: 11555527
Article Published Date : Sep 01, 2001
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-6
Diseases : High Homocysteine, Sleep Apnea: Central
Additional Keywords : Diseases that are Linked
[+]

Hyperhomocysteinaemia, vascular related pregnancy complications respond favorably to vitamin supplementation in pregnant women of Pakistan.Sep 01, 2010

Pubmed Data : J Pak Med Assoc. 2010 Sep;60(9):741-5. PMID: 21381582
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Substances : B-complex, Vitamin B-12, Vitamin B-6
Diseases : Albuminuria: Pregnancy-Associated, Eclampsia, High Homocysteine, Infants: Low Birth Weight, Placental abruption, Pre-Eclampsia, Pregnancy Complications
[+]

L-5-methyltetrahydrofolate effectively reduces total serum homocysteine level in orthotopic liver transplant recipients:.Jun 01, 2008

Pubmed Data : Eur J Clin Nutr. 2008 Jun;62(6):796-801. Epub 2007 May 23. PMID: 17522618
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : 5-Methyltetrahydrofolate (MTHF)
Diseases : High Homocysteine, Organ Transplantation: Liver
[+]

L-dopa causes high homocysteine levels which may be prevented with B-vitamin supplementation.Sep 04, 2008

Pubmed Data : Biometals. 2008 Sep 4. [Epub ahead of print] PMID: 14994447
Article Published Date : Sep 04, 2008
Study Type : Human Study
Additional Links
Substances : B-complex
Diseases : High Homocysteine, Parkinson's Disease
Additional Keywords : Diseases that are Linked
[+]

Lowering homocysteine with folic acids, B-6 and B-12 may have a therapeutic effect on migraine headaches. Jun 01, 2009

Pubmed Data : Pharmacogenet Genomics. 2009 Jun;19(6):422-8. PMID: 19384265
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-12, Vitamin B-6
Diseases : High Homocysteine, Migraine Disorders
Additional Keywords : Diseases that are Linked
[+]

Multiple sclerosis patients tend to have elevated homocysteine blood levels compared to healthy controls.Sep 30, 2017

Pubmed Data : Mult Scler Relat Disord. 2017 Oct ;17:190-197. Epub 2017 Aug 16. PMID: 29055456
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Diseases : Homocysteine: Elevated, Multiple Sclerosis
Additional Keywords : Risk Factors
[+]

Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucrose.Dec 31, 2003

Pubmed Data : J Med Food. 2004 ;7(1):100-7. PMID: 15117561
Article Published Date : Dec 31, 2003
Study Type : Human Study
Additional Links
Substances : Honey
Diseases : C-Reactive Protein, Diabetes Mellitus: Type 2, Hyperhomocysteinemia, Hyperlipidemia
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Honey-sugar Comparison
[+]

ncreased folate and vitamin B6 intakes seem to reduce homocysteine concentrations among transplant recipients with normal renal function, and could contribute to reducing the risk of chronic allograft dysfunction development.Mar 01, 1996

Pubmed Data : Am J Clin Nutr. 1996 Mar;63(3):392-8. PMID: 18089344
Article Published Date : Mar 01, 1996
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-6
Diseases : High Homocysteine, Kidney Transplant
[+]

Oat-bran helps to improve constipation management and B12 bioavailability in elderly, with multiple chronic diseases who live in nursing homes.Mar 01, 2010

Pubmed Data : J Nutr Health Aging. 2010 Mar;14(3):219-23. PMID: 20191257
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Substances : Fiber, Oats, Vitamin B-12
Diseases : Constipation, Elderly: Age Specific Diseases, High Homocysteine, Vitamin B 12 Deficiency
[+]

Oxidative stress-induced DNA damage and homocysteine accumulation may be involved in ovarian cancer progression.Dec 31, 2015

Pubmed Data : Turk J Med Sci. 2016 ;46(3):583-9. Epub 2016 Apr 19. PMID: 27513230
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : DNA damage, High Homocysteine, Ovarian Cancer, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Risk Factors
[+]

Patients with common variable immunodeficiency have enhanced oxidative stress and high homocysteine levels associated with deficiencies of basic vitamins is Sep 01, 1997

Pubmed Data : Eur J Clin Invest. 1997 Sep;27(9):723-30. PMID: 9352241
Article Published Date : Sep 01, 1997
Study Type : Human Study
Additional Links
Substances : beta-Carotene, Folic Acid , Vitamin B-12, Vitamin E
Diseases : Common variable immunodeficiency (CVID) , High Homocysteine
Additional Keywords : Diseases that are Linked
[+]

Patients with obessive-compulsive disorder might have folate deficiency, higher homocysteine levels and probable impaired metylation and monoamine metabolism.Oct 01, 2005

Pubmed Data : Psychiatry Clin Neurosci. 2005 Oct;59(5):616-20. PMID: 16194269
Article Published Date : Oct 01, 2005
Study Type : Human Study
Additional Links
Diseases : Folic Acid/Folate Deficiency, High Homocysteine, Obsessive-Compulsive Disorder
Additional Keywords : Diseases that are Linked, Methylation
[+]

Serum homocysteine may play a role in cognitive dysfunction in MS patients.Feb 20, 2018

Pubmed Data : Int J Neurosci. 2018 Feb 21:1-7. Epub 2018 Feb 21. PMID: 29384421
Article Published Date : Feb 20, 2018
Study Type : Human Study
Additional Links
Diseases : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Multiple Sclerosis
Additional Keywords : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Multiple Sclerosis, Risk Factors
[+]

Significantly lower levels of vitamin B12 and vitamin D and higher levels of homocysteine were found in people with OCD.Dec 31, 2016

Pubmed Data : Psychiatry Res. 2017 08 ;254:232-237. Epub 2017 Apr 21. PMID: 28477545
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin B-12, Vitamin D
Diseases : Homocysteine: Elevated, Obsessive-Compulsive Disorder, Vitamin B 12 Deficiency, Vitamin D Deficiency
[+]

Some OCD patients might have vitamin B12 deficiency and higher homocysteine levels.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2014 ;10:1671-5. Epub 2014 Sep 9. PMID: 25228807
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Diseases : Homocysteine: Elevated, Obsessive-Compulsive Disorder, Vitamin B 12 Deficiency
[+]

Supplementation with Pycnogenol improved the quality of life of perimenopausal women and normalized a series of cardiovascular risk factors.Jan 31, 2017

Pubmed Data : Minerva Ginecol. 2017 Feb ;69(1):29-34. PMID: 28116886
Article Published Date : Jan 31, 2017
Study Type : Human Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : C-Reactive Protein, Homocysteine: Elevated, Perimenopausal Syndrome
Pharmacological Actions : Antioxidants, Cardioprotective
Additional Keywords : Risk Reduction
[+]

Supplementation with vitamin B12 and folic acid in early childhood was associated with a decrease in plasma tHcy concentrations after 6 y.Apr 30, 2023

Pubmed Data : J Nutr. 2023 May ;153(5):1493-1501. Epub 2023 Mar 6. PMID: 36889645
Article Published Date : Apr 30, 2023
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B12
Diseases : Homocysteine: Elevated
[+]

Temporal improvements in vitamin D status reduce serum homocysteine concentrations.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(8):e0161368. Epub 2016 Aug 22. PMID: 27548258
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Cardiovascular Diseases, High Homocysteine
Additional Keywords : Risk Reduction
[+]

The combination of vitamin B-12 and fish oil has a synergistic effect on lowering plasma concentrations of homocysteine.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asia Pac J Clin Nutr. 2015 ;24(3):403-11. PMID: 26420180
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Fish Oil, Omega-3 Fatty Acids, Vitamin B-12
Diseases : C-Reactive Protein, Cardiovascular Diseases, Homocysteine: Elevated
Additional Keywords : Natural Substance Synergy
[+]

The effect of vitamin B12 and folic acid supplementation on serum homocysteine, anemia status and quality of life of patients with multiple sclerosis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Nutr Res. 2019 Jan ;8(1):36-45. Epub 2019 Jan 25. PMID: 30746346
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-12
Diseases : Hyperhomocysteinemia, Multiple Sclerosis
[+]

The present study highlights the significance of micronutrient deficiencies in the causation of depression and anxiety disorder.Mar 31, 2019

Pubmed Data : Clin Nutr ESPEN. 2019 Apr ;30:199-203. Epub 2019 Feb 12. PMID: 30904222
Article Published Date : Mar 31, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : Anxiety, Depression, Hyperhomocysteinemia, Vitamin B 12 Deficiency
Additional Keywords : Increased Risk
[+]

The results of the study show that vitamin B12 deficiency or insufficiency and elevated homocysteine may contribute to the etiopathogenesis of depression. Apr 17, 2020

Pubmed Data : Child Adolesc Ment Health. 2020 Apr 18. Epub 2020 Apr 18. PMID: 32304285
Article Published Date : Apr 17, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : Depression, Homocysteine: Elevated, Vitamin B 12 Deficiency
Additional Keywords : Increased Risk
[+]

There is a potential association of thyrotoxicosis with vitamin B and folate deficiencies, resulting in risk for hyperhomocysteinemia and subsequent thromboembolic events.Jul 01, 2003

Pubmed Data : Endocr Pract. 2003 Jul-Aug;9(4):290-5. PMID: 14561573
Article Published Date : Jul 01, 2003
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : High Homocysteine, Pulmonary Embolism, Pulmonary Thromboembolism, Thromboembolism , Thyrotoxicosis
Additional Keywords : Diseases that are Linked
[+]

There was significant negative correlation of homocysteine with vitamin D and B12 in postmenopausal females.Feb 26, 2018

Pubmed Data : Health Care Women Int. 2018 Feb 27:1-10. Epub 2018 Feb 27. PMID: 29485366
Article Published Date : Feb 26, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin B-12, Vitamin D
Diseases : High Homocysteine, Vitamin B 12 Deficiency, Vitamin D Deficiency
Additional Keywords : High Homocysteine, Vitamin B-12, Vitamin B 12 Deficiency, VITAMIN D, Vitamin D Deficiency
[+]

These results suggest that there is a possible link between migraine, mainly migraine with aura, and elevated serum homocysteine.Jul 01, 2020

Pubmed Data : Headache. 2020 Jul 2. Epub 2020 Jul 2. PMID: 32615014
Article Published Date : Jul 01, 2020
Study Type : Human Study
Additional Links
Diseases : Headache: Migraine, Homocysteine: Elevated
Additional Keywords : Risk Factors
[+]

Vegetarianism produces subclinical malnutrition, hyperhomocysteinemia and atherogenesis.Aug 26, 2011

Pubmed Data : Nutrition. 2011 Aug 26. Epub 2011 Aug 26. PMID: 21872435
Article Published Date : Aug 26, 2011
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, High Homocysteine, Malnourishment
Additional Keywords : Problems with Vegetarianism, Trans-Sulfuration Pathway
[+]

Vitamin B complex improved glycemic control and renal function through decreasing homocysteine.Jan 16, 2019

Pubmed Data : Clin Nutr. 2019 Jan 17. Epub 2019 Jan 17. PMID: 30704890
Article Published Date : Jan 16, 2019
Study Type : Human Study
Additional Links
Substances : B-complex, Thiamine (B-1) , Vitamin B-12, Vitamin B-6
Diseases : Diabetes Mellitus: Type 1, Diabetic Nephropathy, Homocysteine: Elevated
Pharmacological Actions : Hypoglycemic Agents, Renoprotective
[+]

Vitamin B12 is an effective intervention to reduce homocysteine levels.May 01, 2010

Pubmed Data : Eur J Clin Nutr. 2010 May;64(5):495-502. Epub 2010 Mar 10. PMID: 20216560
Article Published Date : May 01, 2010
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : High Homocysteine
[+]

Vitamin B12 treatment reduces homocysteine in patients with mild hyperhomocysteinemia. Nov 01, 2002

Pubmed Data : Ceska Slov Farm. 2002 Nov;51(6):310-2. PMID: 12501494
Article Published Date : Nov 01, 2002
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : High Homocysteine, Vitamin B 12 Deficiency
Therapeutic Actions : Dietary Modification: Vegetarian
[+]

Yoga intervention was found to be associated with reductions in severity of dysmenorrhea.Dec 31, 2012

Pubmed Data : J Altern Complement Med. 2013 Jan ;19(1):20-3. Epub 2012 Sep 10. PMID: 22963270
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Diseases : Dysmenorrhea, Homocysteine: Elevated
Therapeutic Actions : Yoga
[+]

Vitamin deficiencies increased the level of serum homocysteine in this patient. Mar 07, 2016

Pubmed Data : Rinsho Shinkeigaku. 2016 Mar 8 ;56(2):116-9. Epub 2016 Jan 21. PMID: 26797484
Article Published Date : Mar 07, 2016
Study Type : Human: Case Report
Additional Links
Substances : Folate, Vitamin B-12
Diseases : Folic Acid/Folate Deficiency, Homocysteine: Elevated, Thrombosis, Vitamin B 12 Deficiency
[+]

Astaxanthin inhibits homocysteine‑induced endothelial cell dysfunction.Apr 11, 2019

Pubmed Data : Mol Med Rep. 2019 Apr 12. Epub 2019 Apr 12. PMID: 31059085
Article Published Date : Apr 11, 2019
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Endothelial Dysfunction, Homocysteine: Elevated, Hyperhomocysteinemia
Pharmacological Actions : Antioxidants, Vascular Endothelial Growth Factor Inhibitors
[+]

Astaxanthin may be a highly efficient way to combat homocysteine mediated human cardiovascular diseases.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2017 ;8:1041. Epub 2017 Dec 12. PMID: 29311972
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Cardiovascular Diseases, High Homocysteine
Pharmacological Actions : Cardioprotective
[+]

Astragalus contains a compound called astragaloside IV which improves homocysteine-induced acute phase endothelial dysfunction via antioxidation.Jan 01, 2010

Pubmed Data : Biol Pharm Bull. 2010;33(4):641-6. PMID: 20410599
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Astragalus
Diseases : Endothelial Dysfunction, Homocysteine: Elevated
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Berberine may have therapeutic value in those with high homocysteine by regulating liver cholesterol synthesis.Dec 22, 2010

Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2010 Dec 22. Epub 2010 Dec 22. PMID: 21178122
Article Published Date : Dec 22, 2010
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : High Cholesterol, High Homocysteine
[+]

Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia.Dec 01, 2007

Pubmed Data : Atherosclerosis. 2007 Dec;195(2):e100-7. Epub 2007 Aug 9. PMID: 17689540
Article Published Date : Dec 01, 2007
Study Type : Transgenic Animal Study
Additional Links
Substances : Betaine
Diseases : High Homocysteine
[+]

Compounds in Astragalus protect against homocysteine-induced injury to the lining of the arteries.Apr 01, 2007

Pubmed Data : Vascul Pharmacol. 2007 Apr;46(4):278-85. Epub 2006 Nov 10. PMID: 17196887
Article Published Date : Apr 01, 2007
Study Type : Animal Study
Additional Links
Substances : Astragalus
Diseases : Endothelial Damage, Endothelial Dysfunction, High Homocysteine
Pharmacological Actions : Antioxidants, Cardioprotective, Vasodilator Agents
Additional Keywords : Plant Extracts
[+]

Consumption of cashew nuts counteracts oxidative stress and tissue inflammation in mild hyperhomocysteinemia. Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Apr 1 ;14(7). Epub 2022 Apr 1. PMID: 35406088
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Cashew
Diseases : Hyperhomocysteinemia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Gastroprotective, Hepatoprotective, Renoprotective
[+]

Creatinine supplementation decreases homocysteine in an animal model of uremia. Oct 01, 2003

Pubmed Data : Kidney Int. 2003 Oct;64(4):1331-7. PMID: 12969151
Article Published Date : Oct 01, 2003
Study Type : Animal Study
Additional Links
Substances : Creatine
Diseases : Hyperhomocysteinemia, Uremia
[+]

Curcumin exerts neuroprotective effects against homocysteine intracerebroventricular injection-induced cognitive impairment and oxidative stress in rat brain.Oct 01, 2010

Pubmed Data : Exp Neurol. 2010 Oct;225(2):237-9. Epub 2010 Jul 11. PMID: 20553189
Article Published Date : Oct 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Homocysteine: Elevated, Learning disorders, Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin has a neuroprotective effect against homocysteine-induced cognitive impairment and oxidative stress in the rat.Oct 01, 2010

Pubmed Data : Pharmacol Biochem Behav. 2010 Oct;96(4):378-85. Epub 2010 Jul 6. PMID: 20619287
Article Published Date : Oct 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Curcumin protects against methionine-induced hyperlipidemia and hyperhomocysteinemia in rats. Jul 01, 2008

Pubmed Data : Indian J Exp Biol. 2008 Jul;46(7):534-40. PMID: 18807758
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : High Homocysteine, Hyperlipidemia
[+]

Embelia ribes has a protective effective against methionine-induced hyperhomocysteinemia and oxidative stress in rat brain.Jul 01, 2008

Pubmed Data : Indian J Exp Biol. 2008 Jul;46(7):521-7. PMID: 18807756
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Embelia ribes
Diseases : High Homocysteine
Additional Keywords : Plant Extracts
[+]

Emodin represents a novel potential candidate agent for hyperhomocysteinemia-induced dementia and Alzheimer's disease-like features.Nov 07, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Neuropsychopharmacol. 2018 Nov 8. Epub 2018 Nov 8. PMID: 30407508
Article Published Date : Nov 07, 2018
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Alzheimer's Disease, Dementia, Hyperhomocysteinemia
Pharmacological Actions : Neuroprotective Agents
[+]

Fisetin exerts endothelial and neuroprotective effects against hyperhomocysteinemia induced endothelial dysfunction and vascular dementia.Dec 31, 2016

Pubmed Data : Can J Physiol Pharmacol. 2017 Jan ;95(1):32-42. Epub 2016 Aug 11. PMID: 27901381
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Dementia, Endothelial Dysfunction, Hyperhomocysteinemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Dose Response
[+]

Folate supplementation inhibits carotid artery thickening induced by a high-homocysteine diet in a rat model. Sep 01, 2001

Pubmed Data : J Vasc Surg. 2001 Sep;34(3):474-81. PMID: 11533600
Article Published Date : Sep 01, 2001
Study Type : Animal Study
Additional Links
Diseases : Carotid Stenosis, Hyperhomocysteinemia, Intima Media Thickening , Restenosis
[+]

Folic acid can protect cerebellum against homocysteine-mediated neurotoxicity.Nov 12, 2019

Pubmed Data : Neurotox Res. 2019 Nov 13. Epub 2019 Nov 13. PMID: 31721048
Article Published Date : Nov 12, 2019
Study Type : Animal Study
Additional Links
Substances : Folic Acid
Diseases : Homocysteine: Elevated
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
[+]

Folic acid supplementation increased high-density lipoprotein-cholesterol, decreased plasma homocysteine levels and improved antioxidant capacity.Jun 01, 2017

Pubmed Data : Appl Physiol Nutr Metab. 2017 Jun 2. Epub 2017 Jun 2. PMID: 28575637
Article Published Date : Jun 01, 2017
Study Type : Animal Study
Additional Links
Substances : Folic Acid
Diseases : Atherosclerosis, Homocysteine: Elevated
Pharmacological Actions : Antioxidants
Additional Keywords : Antioxidants, Atherosclerosis, folic acid, Homocysteine: Elevated
[+]

Ginkgolide A attenuates homocysteine-induced endothelial dysfunction in porcine coronary arteries.Sep 30, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Vasc Surg. 2006 Oct ;44(4):853-62. PMID: 17012008
Article Published Date : Sep 30, 2006
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Atherosclerosis, Endothelial Dysfunction, Homocysteine: Elevated
Pharmacological Actions : Cardioprotective, Vasoprotective
Additional Keywords : Phytotherapy
[+]

Hydroxysafflor yellow A ameliorates homocysteine-induced Alzheimer-like pathologic dysfunction and memory/synaptic disorder.Nov 30, 2013

Pubmed Data : Rejuvenation Res. 2013 Dec ;16(6):446-52. PMID: 23837610
Article Published Date : Nov 30, 2013
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Alzheimer's Disease, Homocysteine: Elevated
Pharmacological Actions : Neuroprotective Agents
[+]

Hyperhomocysteinemia exaggerates adventitial inflammation and angiotensin II-induced abdominal aortic aneurysm in mice.Oct 25, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Circ Res. 2012 Oct 26 ;111(10):1261-73. Epub 2012 Aug 21. PMID: 22912384
Article Published Date : Oct 25, 2012
Study Type : Animal Study
Additional Links
Diseases : Aneurysm: Aortic, High Homocysteine
Pharmacological Actions : Interleukin-6 Downregulation
Additional Keywords : Risk Factors
[+]

L-Glutamic acid, L-histidine, and L-arginine significantly suppressed methionine-induced enhancement of plasma homocysteine concentrationsJul 01, 2008

Pubmed Data : Biosci Biotechnol Biochem. 2008 Jul;72(7):1940-3. Epub 2008 Jul 7. PMID: 18603771
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Arginine, Histidine
Diseases : High Homocysteine
[+]

Melatonin inhibits oxidative stress and programmed cell death in fetal brains of hyperhomocysteinemic rat dams.Oct 01, 2007

Pubmed Data : J Pineal Res. 2007 Oct;43(3):225-31. PMID: 17803518
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : High Homocysteine, Lipid Peroxidation, Oxidative Stress, Prenatal Nutrition: Prevention of Problems
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Neuroprotective Agents, Tumor Suppressor Protein p53 Upregulation
[+]

Quercetin reduces serum homocysteine level in rats fed a methionine-enriched diet.Mar 31, 2013

Pubmed Data : Nutrition. 2013 Apr ;29(4):661-6. Epub 2013 Feb 12. PMID: 23410631
Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Homocysteine: Elevated
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
[+]

Red wine polyphenols protect and reverse liver fibrosis in mice with elevated homocysteine.Dec 23, 2010

Pubmed Data : J Nutr Biochem. 2010 Dec 23. Epub 2010 Dec 23. PMID: 21185709
Article Published Date : Dec 23, 2010
Study Type : Animal Study
Additional Links
Substances : Polyphenols, Red Wine Extract
Diseases : High Homocysteine, Liver Fibrosis
Pharmacological Actions : Cardioprotective
[+]

Supplementation with folic acid and l-arginine has an antiepileptic effect in dl homocysteine thiolactone induced epilepsy.Jun 21, 2016

Pubmed Data : Can J Physiol Pharmacol. 2016 Jun 22:1-7. Epub 2016 Jun 22. PMID: 27494641
Article Published Date : Jun 21, 2016
Study Type : Animal Study
Additional Links
Substances : Arginine, Folic Acid
Diseases : High Homocysteine, Seizures
Pharmacological Actions : Anticonvulsants
[+]

Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats.Dec 31, 2003

Pubmed Data : Int J Cardiol. 2004 Jan ;93(1):19-23. PMID: 14729430
Article Published Date : Dec 31, 2003
Study Type : Animal Study
Additional Links
Substances : Methionine, Nigella sativa (aka Black Seed), Thymoquinone
Diseases : High Homocysteine, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Vitamin B complex mitigates cardiac dysfunction in high-methionine diet-induced hyperhomocysteinemia.Mar 05, 2018

Pubmed Data : Clin Exp Pharmacol Physiol. 2018 Mar 6. Epub 2018 Mar 6. PMID: 29509296
Article Published Date : Mar 05, 2018
Study Type : Animal Study
Additional Links
Substances : Folic Acid , Vitamin B-12, Vitamin B-6
Diseases : Hyperhomocysteinemia
Pharmacological Actions : Cardioprotective
Additional Keywords : Cardioprotective, folic acid, Hyperhomocysteinemia, Vitamin B-12, Vitamin B-6
[+]

A Mediterranean diet may protect against homocysteine-induced cardiovascular damage. Sep 01, 2010

Pubmed Data : Chemosphere. 2010 Sep;81(4):464-8. PMID: 17586618
Article Published Date : Sep 01, 2010
Study Type : Commentary
Additional Links
Substances : Flavonoids, Hydroxytyrosol, Polyphenols, Resveratrol
Diseases : High Homocysteine
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Antioxidants, Proteasome Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords : Stilbenes
[+]

Astaxanthin protects PC12 cells against homocysteine- and glutamate-induced neurotoxicity.Jan 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Jan 5 ;25(1). Epub 2020 Jan 5. PMID: 31948056
Article Published Date : Jan 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Alzheimer's Disease: Homocysteine Associated, Homocysteine: Elevated, Memory Disorders
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Beer consumption is associated with lower levels of homocysteine due to its high B6 content. Feb 15, 2003

Pubmed Data : 1: Presse Med. 2003 Feb 15;32(6):262-7. PMID:12610455
Article Published Date : Feb 15, 2003
Study Type : Review
Additional Links
Substances : Beer
Diseases : High Homocysteine, Hyperhomocysteinemia
[+]

Curcumin prevents homocysteine-induced endothelial dysfunction in porcine coronary arteries. Sep 01, 2001

Pubmed Data : Biol Pharm Bull. 2001 Sep;24(9):1091-2. PMID: 15622377
Article Published Date : Sep 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Endothelial Dysfunction, Hyperhomocysteinemia
[+]

Folic acid relieves rat cardiomyocyte injury induced by homocystein through DNA methylation.Jun 30, 2019

Pubmed Data : Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2019 Jul ;35(7):625-630. PMID: 31537248
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid
Diseases : Homocysteine: Elevated
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
Additional Keywords : DNA Methylation
[+]

Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries.May 01, 2005

Pubmed Data : J Vasc Surg. 2005 May;41(5):861-8. PMID: 15886672
Article Published Date : May 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Ginseng, unspecified species
Diseases : Hyperhomocysteinemia
[+]

Ginsenoside Rb1 prevents homocysteine-induced dysfunction of endothelial progenitor cells. Oct 11, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Oct 12 ;7(1):13061. Epub 2017 Oct 12. PMID: 29026158
Article Published Date : Oct 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Cardiovascular Diseases, Endothelial Damage, Homocysteine: Elevated, Hyperhomocysteinemia
Pharmacological Actions : Cardioprotective
[+]

Goji has neuroprotective properties against homocysteine-induced toxicity in rat cortical neurons.Jan 01, 2010

Pubmed Data : J Alzheimers Dis. 2010;19(3):813-27. PMID: 20157238
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Goji
Diseases : Alzheimer's Disease, High Homocysteine
Pharmacological Actions : Apoptotic, Neuroprotective Agents
[+]

Homocysteine can be a potential therapeutic target for the treatment of psoriasis.Nov 28, 2019

Pubmed Data : Biosci Rep. 2019 Nov 29 ;39(11). PMID: 31670376
Article Published Date : Nov 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid , Vitamin B-12
Diseases : Homocysteine: Elevated, Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Hyperhomocysteinemia is associated with cardiac pathological conditions.Jan 01, 2010

Pubmed Data : Curr Vasc Pharmacol. 2010 Jan;8(1):64-74. PMID: 19485933
Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Substances : B-complex
Diseases : Arrhythmias: Cardiac, Cardiac Mortality , Coronary Artery Disease, High Homocysteine, Myocardial Infarction
Additional Keywords : Diseases that are Linked
[+]

In the current review, an attempt has been made to discuss the neurotoxic effects of homocysteine in the pathogenesis of depression.Aug 26, 2015

Pubmed Data : Fundam Clin Pharmacol. 2015 Aug 27. Epub 2015 Aug 27. PMID: 26376956
Article Published Date : Aug 26, 2015
Study Type : Review
Additional Links
Diseases : Depression, Folic Acid/Folate Deficiency, High Homocysteine
Additional Keywords : Risk Factors
[+]

Isoflavones protect against homocysteine-mediated neuronal degeneration. Aug 01, 2010

Pubmed Data : Amino Acids. 2010 Aug;39(3):785-94. Epub 2010 Mar 4. PMID: 20204436
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Isoflavones
Diseases : Homocysteine: Elevated
Pharmacological Actions : Apoptotic, Neuroprotective Agents
[+]

Levodopa treatment of Parkinsons disease results in hyperhomocysteinemia, which would be prevented by increased intake of vitamin b12, vitamin b6 and folate.Feb 01, 2008

Pubmed Data : CNS Neurol Disord Drug Targets. 2008 Feb;7(1):20-7. PMID: 18289028
Article Published Date : Feb 01, 2008
Study Type : Review
Additional Links
Substances : Folic Acid , Vitamin B-12, Vitamin B-6
Diseases : High Homocysteine, Parkinson's Disease
Additional Keywords : Diseases that are Linked
[+]

Methyl Vitamin B12 rescues a motor neuron-like cell line from homocysteine-mediated cell death.Mar 15, 2011

Pubmed Data : Toxicol Appl Pharmacol. 2011 Mar 15;251(3):217-25. Epub 2011 Jan 13. PMID: 21237187
Article Published Date : Mar 15, 2011
Study Type : In Vitro Study
Additional Links
Substances : Vitamin B12: methylcobalamin , Vitamin B-12
Diseases : Amyotrophic Lateral Sclerosis, High Homocysteine, Neuroblastoma
Pharmacological Actions : Neuroprotective Agents
[+]

Naringenin induces neuroprotection against homocysteine-induced PC12 cells.Feb 29, 2020

Pubmed Data : J Biol Regul Homeost Agents. 2020 Mar-Apr;34(2):421-433. PMID: 32515177
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Naringenin
Diseases : Brain: Oxidative Stress, Hyperhomocysteinemia
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Resveratrol may protect against hyperhomocysteinemia-incued cardiovascular disease.Nov 01, 2010

Pubmed Data : Thromb Res. 2010 Nov;126(5):e379-82. PMID: 20869101
Article Published Date : Nov 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Cardiovascular Diseases, Hyperhomocysteinemia
Pharmacological Actions : Cardioprotective
[+]

Tanshinone ⅡA inhibits homocysteine-induced proliferation of vascular smooth muscle cells.Jan 28, 2020

Pubmed Data : Biochem Biophys Res Commun. 2020 Jan 29 ;522(1):157-163. Epub 2019 Nov 19. PMID: 31757424
Article Published Date : Jan 28, 2020
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Atherosclerosis, Homocysteine: Elevated
Pharmacological Actions : Antiproliferative , MicroRNA modulator
[+]

Tetrahydrocurcumin ameliorates homocysteine-mediated mitochondrial remodeling in brain endothelial cells.Dec 31, 2017

Pubmed Data : J Cell Physiol. 2018 04 ;233(4):3080-3092. Epub 2017 Nov 14. PMID: 28833102
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Tetrahydrocurcumin
Diseases : Homocysteine: Elevated
Pharmacological Actions : Apoptotic
[+]

Vitamin B-12 deficiency may lead to an increase in the concentration of homocysteine.Apr 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Nutr. 2017 May ;8(3):463-472. Epub 2017 May 15. PMID: 28507011
Article Published Date : Apr 30, 2017
Study Type : Review
Additional Links
Substances : Vitamin B-12, Vitamin D
Diseases : High Homocysteine, Multiple Sclerosis, Vitamin B 12 Deficiency
[+]

Choline may prevent increased homocysteine concentrations which may reduce cardiovascular risk.Jul 01, 2005

Pubmed Data : Am J Clin Nutr. 2005 Jul;82(1):111-7. PMID: 16002808
Article Published Date : Jul 01, 2005
Additional Links
Substances : Choline
Diseases : Hyperhomocysteinemia
[+]

Red Yeast Rice inhibits homocysteine-induced endothelial damage.Mar 01, 2008

Pubmed Data : J Biomed Sci. 2008 Mar;15(2):183-96. Epub 2007 Sep 30. read PMID: 17906965
Article Published Date : Mar 01, 2008
Additional Links
Diseases : Hyperhomocysteinemia

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