Hyperinsulinism

Name	AC	CK
Fiber	4	32
Berries: All	1	20
Chocolate	1	20
Cocoa	1	20
Flavan-3-ols	1	20
Acetic Acid	1	10
Almond	1	10
Alpha-Lipoic Acid	1	10
Beta-glucan	1	10
Black Currant	1	10
Bran	1	10
Broccoli Sprouts	1	10
Cayenne	1	10
Chili pepper	1	10
Chinese Herbal Formula: Tiangui Fang	1	10
Lingonberry	1	10
Monounsaturated fatty acids	1	10
Oleic acid	1	10
Omega-3 Fatty Acids	1	10
Rye	1	10
Sulforaphane	1	10
Vinegar	1	10
Walnut	1	10
Wheat Bran	1	10
Nigella sativa (aka Black Seed)	3	6
Coffee	2	4
Polyphenols	2	4
Turmeric	2	4
Vanillic Acid	2	3
Anthocyanins	1	2
Blue Honeysuckle	1	2
Chinese Skullcap	1	2
Curcumin	1	2
Garlic	1	2
Ginger	1	2
Grape	1	2
Grape Seed Extract	1	2
Krill	1	2
Lactobacillus casei	1	2
Litchi	1	2
Loquat	1	2
Magnesium	1	2
Maitake Mushroom	1	2
Mangiferin	1	2
Prickly Pear Cactus	1	2
Proanthocyanidins	1	2
Psyllium	1	2
Theanine	1	2
Ursolic Acid	1	2
Vanadyl Sulfate	1	2
Yerba Mate	1	2
Apigenin	1	1
Fisetin	1	1
Flavonoids	1	1
Kaempferol	1	1
Luteolin	1	1
Quercetin	1	1
Raisins	1	1

Name	AC	CK
Insulin	7	38
Fructose	9	20
Rye	1	20
Wheat	1	20
Sucrose	1	10
Sugar Sweetened Beverages	1	10
Acesulfame potassium	3	5
Gluten	2	4
Monosodium Glutamate (MSG)	2	4
Cow Milk	2	3
Aspartame	1	2
Ethanol	1	2
Gliadin	1	2
Gluten exorphins	1	2
Metformin	1	2
Trans Fatty Acids	1	2
Artificial Sweeteners	1	1
Concanavalin A	1	1
Saccharin	1	1
Sodium Cyclamate	1	1
Wheat Germ Agglutinin (WGA)	1	1

Name	AC	CK
Fasting/Caloric Restriction	2	20
Blood Donation	1	10
Dietary Modification: Caloric Restriction	1	10
Phlebotomy	1	10
Dietary Modification: Low Carbohydrate/Ketogenic	1	3
Exercise	1	2

Name	AC	CK	Focus
Western Diet	1	2

[+]

Meta-analysis: Chocolate, cocoa and flavan-3-ols improve insulin resistance, reduces serum insulin levels, and parameters associated with cardiovascular disease risk. Feb 01, 2012

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2012 Feb 1. Epub 2012 Feb 1. PMID: 22301923

Article Published Date : Feb 01, 2012

Study Type : Meta Analysis

Additional Links

Substances : Chocolate, Cocoa, Flavan-3-ols

Diseases : Cardiovascular Diseases, Hypertension, Insulin: Elevated, Insulin Resistance

Pharmacological Actions : Hypotensive

[+]

After 4 weeks consuming broccoli sprouts powder it resulted in a significant decrease in serum insulin concentration in patients. Oct 31, 2012

Click here to read the entire abstract

Pubmed Data : Int J Food Sci Nutr. 2012 Nov ;63(7):767-71. Epub 2012 Apr 26. PMID: 22537070

Article Published Date : Oct 31, 2012

Study Type : Human Study

Additional Links

Substances : Broccoli Sprouts, Sulforaphane

Diseases : Diabetes Mellitus: Type 2, Hyperinsulinism, Insulin Resistance

Pharmacological Actions : Antioxidants, Insulin Down-Regulation

[+]

Almonds reduce insulin secretion and insulin resistance in nondiabetic hyperlipidemic subjects. Jul 01, 2008

Click here to read the entire abstract

Pubmed Data : Metabolism. 2008 Jul;57(7):882-7. PMID: 18555827

Article Published Date : Jul 01, 2008

Study Type : Human Study

Additional Links

Substances : Almond

Diseases : Hyperinsulinism, Hyperlipidemia

[+]

Berries reduce postprandial insulin responses to wheat and rye breads in healthy women.Mar 31, 2013

Click here to read the entire abstract

Pubmed Data : J Nutr. 2013 Apr ;143(4):430-6. Epub 2013 Jan 30. PMID: 23365108

Article Published Date : Mar 31, 2013

Study Type : Human Study

Additional Links

Substances : Berries: All

Diseases : Hyperinsulinism, Insulin: Elevated, Insulin Resistance

Pharmacological Actions : Insulin Sensitizers

Problem Substances : Rye, Wheat

Adverse Pharmacological Actions : Insulinotropic

[+]

Caloric restriction ameliorates defective insulin binding to receptors in obese men. Jan 01, 1975

Click here to read the entire abstract

Pubmed Data : J Clin Invest. 1975 Jan;55(1):166-74. PMID: 1109176

Article Published Date : Jan 01, 1975

Study Type : Human Study

Additional Links

Diseases : Hyperinsulinism, Insulin Resistance

Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction

[+]

Clamping cortisol and testosterone mitigates the development of insulin resistance during sleep restriction in men.Aug 17, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Endocrinol Metab. 2021 Aug 18 ;106(9):e3436-e3448. PMID: 34043794

Article Published Date : Aug 17, 2021

Study Type : Human Study

Additional Links

Diseases : Hyperinsulinism, Insomnia, Insulin Resistance, Sleep Disorders

[+]

Controlled-release alpha lipoic acid has a therapeutic effect in lean, nondiabetic patients with polycystic ovary syndrome.Mar 01, 2010

Click here to read the entire abstract

Pubmed Data : J Diabetes Sci Technol. 2010 Mar;4(2):359-64. Epub 2010 Mar 1. PMID: 20307398

Article Published Date : Mar 01, 2010

Study Type : Human Study

Additional Links

Substances : Alpha-Lipoic Acid

Diseases : Hyperinsulinism, Insulin Resistance, Oxidative Stress, Polycystic Ovary Syndrome

[+]

Four grams of high molecular weight oat β-glucan lowers appetite but not ad libitum eating and beneficially modulates postprandial glycemia.Jan 01, 2018

Click here to read the entire abstract

Pubmed Data : Appetite. 2018 09 1 ;128:197-204. Epub 2018 Jun 18. PMID: 29920323

Article Published Date : Jan 01, 2018

Study Type : Human Study

Additional Links

Substances : Beta-glucan

Diseases : Hyperglycemia, Hyperinsulinism

Pharmacological Actions : Hypoglycemic Agents

Problem Substances : Insulin

[+]

Higher insulin concentrations, as well as the presence of insulin resistance, appear to be associated with an elevated risk of lung cancer development.Jul 10, 2017

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Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2017 Jul 11. Epub 2017 Jul 11. PMID: 28698186

Article Published Date : Jul 10, 2017

Study Type : Human Study

Additional Links

Diseases : Insulin: Elevated, Insulin Resistance, Lung Cancer

Additional Keywords : Risk Factors

[+]

In patients with METS, phlebotomy, with consecutive reduction of body iron stores, lowered BP and resulted in improvements in markers of cardiovascular risk and glycemic control.Dec 31, 2011

Click here to read the entire abstract

Pubmed Data : BMC Med. 2012 ;10:54. Epub 2012 May 30. PMID: 22647517

Article Published Date : Dec 31, 2011

Study Type : Human Study

Additional Links

Diseases : Hyperinsulinism, Hypertension, Insulin Resistance, Metabolic Syndrome X

Therapeutic Actions : Blood Donation, Phlebotomy

[+]

Insulinemic and inflammatory dietary patterns and risk of prostate cancer. Jan 05, 2021

Click here to read the entire abstract

Pubmed Data : Eur Urol. 2021 Jan 6. Epub 2021 Jan 6. PMID: 33422354

Article Published Date : Jan 05, 2021

Study Type : Human Study

Additional Links

Diseases : Hyperinsulinism, Inflammation, Prostate Cancer

Additional Keywords : Inflammatory Diet, Risk Factors

[+]

Orange pomace fiber lowers postprandial glycemic and insulinemic responses in men with increased cardiometabolic risk.Jan 01, 2016

Click here to read the entire abstract

Pubmed Data : J Nutr. 2016 06 ;146(6):1197-203. Epub 2016 May 11. PMID: 27170728

Article Published Date : Jan 01, 2016

Study Type : Human Study

Additional Links

Substances : Fiber

Diseases : Cardiovascular Diseases, Hyperglycemia, Hyperinsulinism

Pharmacological Actions : Hypoglycemic Agents

Problem Substances : Insulin

[+]

Postmeal fluctuations in blood glucose and insulin induced by sucrose are alleviated when sucrose is consumed with blackcurrants or lingonberries. Aug 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Am J Clin Nutr. 2012 Sep ;96(3):527-33. Epub 2012 Aug 1. PMID: 22854401

Article Published Date : Aug 31, 2012

Study Type : Human Study

Additional Links

Substances : Black Currant, Lingonberry

Diseases : Hyperinsulinism

Pharmacological Actions : Glucose Uptake Optimization

Additional Keywords : Metabolic Regulation

Problem Substances : Insulin , Sucrose

[+]

Pre-exercise carbohydrate ingestion after a 4-hour fast is sufficient to induce a transient hypoglycemia.May 01, 1999

Click here to read the entire abstract

Pubmed Data : Int J Sports Med. 1999 May;20(4):227-31. PMID: 10376478

Article Published Date : May 01, 1999

Study Type : Human Study

Additional Links

Diseases : Hyperinsulinism, Hypoglycemia

[+]

Regular consumption of chili may attenuate postprandial hyperinsulinemia.Jul 01, 2006

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2006 Jul;84(1):63-9. PMID: 16825682

Article Published Date : Jul 01, 2006

Study Type : Human Study

Additional Links

Substances : Cayenne, Chili pepper

Diseases : Hyperinsulinism

Therapeutic Actions : Fasting/Caloric Restriction

[+]

Substituting saturated fats with monounsaturated fats within high-fat diets attenuates hyperinsulinemia and pancreatic islet dysfunction.Mar 03, 2020

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2020 Mar 3:1-22. Epub 2020 Mar 3. PMID: 32122411

Article Published Date : Mar 03, 2020

Study Type : Human Study

Additional Links

Substances : Monounsaturated fatty acids, Oleic acid

Diseases : Hyperinsulinism, Pancreatic Diseases

Pharmacological Actions : Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK, Anti-Inflammatory Agents

[+]

The Chinese herbal formula "tiangui fang" may have value in the treatment of hyperandrogenism and hyperinsulinism in polycystic ovary syndrome.Aug 01, 2000

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Aug ;20(8):589-92. PMID: 11789189

Article Published Date : Aug 01, 2000

Study Type : Human Study

Additional Links

Substances : Chinese Herbal Formula: Tiangui Fang

Diseases : Adrenal Hyperandrogenism, Hyperinsulinism, Polycystic Ovary Syndrome

Pharmacological Actions : Hypoglycemic Agents

Additional Keywords : Drug: Metformin

[+]

The consumption of sugar-sweetened beverages was associated with higher concentrations of insulin and leptin and a higher HOMA-IR.Jun 30, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr. 2014 Jul ;144(7):1099-105. Epub 2014 May 14. PMID: 24828025

Article Published Date : Jun 30, 2014

Study Type : Human Study

Additional Links

Diseases : Hyperinsulinism, Insulin Resistance

Additional Keywords : Risk Factors

Problem Substances : Sugar Sweetened Beverages

[+]

Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects.Sep 01, 2005

Click here to read the entire abstract

Pubmed Data : Eur J Clin Nutr. 2005 Sep ;59(9):983-8. PMID: 16015276

Article Published Date : Sep 01, 2005

Study Type : Human Study

Additional Links

Substances : Acetic Acid, Vinegar

Diseases : Hyperinsulinism

Pharmacological Actions : Hypoglycemic Agents

[+]

Walnuts may improve metabolic parameters in type II diabetes.Aug 01, 2009

Click here to read the entire abstract

Pubmed Data : Eur J Clin Nutr. 2009 Aug ;63(8):1008-15. Epub 2009 Apr 8. PMID: 19352378

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids, Walnut

Diseases : Diabetes Mellitus: Type 2, Hyperinsulinism, Metabolic Syndrome X

[+]

Wheat fiber supplementation increases GLP-1 secretion and improves colonic fermentation by-products in hyperinsulinemic patients. Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2010 Jan;103(1):82-90. Epub 2009 Aug 7. PMID: 19664300

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Fiber, Wheat Bran

Diseases : Hyperinsulinism, Insulin Resistance

Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation

[+]

Whole grain and bran from rye resulted in significantly lower plasma PSA in patients with prostate cancer.Dec 01, 2010

Click here to read the entire abstract

Pubmed Data : J Nutr. 2010 Dec;140(12):2180-6. Epub 2010 Oct 27. PMID: 20980650

Article Published Date : Dec 01, 2010

Study Type : Human Study

Additional Links

Substances : Bran , Fiber, Rye

Diseases : Hyperinsulinism, Prostate Cancer

[+]

The ketogenic diet could represent an effective treatment to support brain function in selected cases of congenital hyperinsulinism.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Orphanet J Rare Dis. 2015 ;10(1):120. Epub 2015 Sep 24. PMID: 26399329

Article Published Date : Dec 31, 2014

Study Type : Human: Case Report

Additional Links

Diseases : Congenital Disorders, Hyperinsulinism, Seizures

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Additional Keywords : Significant Treatment Outcome

[+]

"Brain insulin impairs amyloid-beta(1-40) clearance from the brain."Oct 26, 2004

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Neurosci. 2004 Oct 27 ;24(43):9632-7. PMID: 15509750

Article Published Date : Oct 26, 2004

Study Type : Animal Study

Additional Links

Diseases : Aging: Brain , Hyperinsulinism

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Insulin

[+]

A combination of black seeds and turmeric at low doses showed enhanced efficacy in preventing metabolic syndrome in fructose fed rats.Jan 31, 2015

Click here to read the entire abstract

Pubmed Data : J Cardiovasc Pharmacol. 2015 Feb ;65(2):176-83. PMID: 25384193

Article Published Date : Jan 31, 2015

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed), Turmeric

Diseases : Dyslipidemias, Endothelial Dysfunction, Fructose-Induced Toxicity , Hyperglycemia, Hyperinsulinism, Hypertension, Metabolic Diseases

Pharmacological Actions : Anticholesteremic Agents, Antihypertensive Agents, Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Natural Substance Synergy, Risk Reduction

[+]

A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats.Jan 01, 2012

Click here to read the entire abstract

Pubmed Data : PLoS One. 2012 ;7(6):e38797. Epub 2012 Jun 7. PMID: 22685607

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Substances : Krill

Diseases : Fatty Liver, Insulin: Elevated, Triglycerides: Elevated

Pharmacological Actions : Hepatoprotective

[+]

A water extract of maitake mushroom reduces circulating glucose/insulin concentrations in insulin-resistant mice. Jan 01, 2002

Click here to read the entire abstract

Pubmed Data : Diabetes Obes Metab. 2002 Jan;4(1):43-8. PMID: 11874441

Article Published Date : Jan 01, 2002

Study Type : Animal Study

Additional Links

Substances : Maitake Mushroom

Diseases : Hyperinsulinism, Insulin Resistance

Pharmacological Actions : Hypoglycemic Agents

[+]

Acesulfame K acts directly on the pancreatic islets and potentiates glucose-induced insulin release.Jul 01, 1987

Click here to read the entire abstract

Pubmed Data : Horm Metab Res. 1987 Jul;19(7):285-9. PMID: 2887503

Article Published Date : Jul 01, 1987

Study Type : Animal Study

Additional Links

Diseases : Hyperinsulinism

Problem Substances : Acesulfame potassium

[+]

Acesulfame stimulates insulin secretion. Jun 01, 1987

Click here to read the entire abstract

Pubmed Data : Horm Metab Res. 1987 Jun;19(6):233-8. PMID: 2887500

Article Published Date : Jun 01, 1987

Study Type : Animal Study

Additional Links

Diseases : Hyperinsulinism

Problem Substances : Acesulfame potassium

[+]

An anthocyanin-rich Kamchatka honeysuckle berry extract supplemented to an unbalanced diet is able to ameliorate disturbances in lipid/glucose metabolism that are risk factors for CVD and diabetes.May 31, 2013

Click here to read the entire abstract

Pubmed Data : Nutrition. 2013 Jun ;29(6):898-902. Epub 2013 Feb 16. PMID: 23422536

Article Published Date : May 31, 2013

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Blue Honeysuckle

Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2: Prevention, Fructose-Induced Toxicity , Hyperinsulinism, Hyperlipidemia, Insulin Resistance, Triglycerides: Elevated

Pharmacological Actions : Alpha-glucosidase inhibitor , Cardioprotective, Hypolipidemic

Additional Keywords : Metabolism Of Polyphenols, Plant Extracts, Risk Reduction

[+]

Aspartame exposure may promote hyperglycemia and insulin intolerance. MSG may interact with aspartame to further impair glucose homeostasis.Jun 14, 2012

Click here to read the entire abstract

Pubmed Data : Nutr Metab (Lond). 2012 Jun 14 ;9(1):58. Epub 2012 Jun 14. PMID: 22697049

Article Published Date : Jun 14, 2012

Study Type : Animal Study

Additional Links

Diseases : Hyperglycemia, Insulin: Elevated, Insulin Resistance

Problem Substances : Aspartame, Monosodium Glutamate (MSG)

Adverse Pharmacological Actions : Diabetogenic, Endocrine Disruptor: Insulin Resistance

[+]

Baicalin suppresses body weight gain, visceral fat mass, serum cholesterol, free fatty acid and insulin concentrations caused by a high-fat diet. Nov 01, 2009

Click here to read the entire abstract

Pubmed Data : Acta Pharmacol Sin. 2009 Nov;30(11):1505-12. PMID: 19890358

Article Published Date : Nov 01, 2009

Study Type : Animal Study

Additional Links

Substances : Chinese Skullcap

Diseases : Abdominal Obesity (Midsection Fat), Fatty Liver, Hyperinsulinism, Obesity

[+]

Coffee polyphenols modulate whole-body substrate oxidation and suppress postprandial hyperglycaemia, hyperinsulinaemia and hyperlipidaemia.Jun 01, 2012

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2012 Jun ;107(12):1757-65. Epub 2011 Sep 29. PMID: 22017960

Article Published Date : Jun 01, 2012

Study Type : Animal Study

Additional Links

Substances : Coffee, Polyphenols

Diseases : Hyperglycemia, Hyperinsulinism, Hyperlipidemia

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Coffee polyphenols modulate whole-body substrate oxidation and suppress postprandial hyperglycaemia, hyperinsulinaemia and hyperlipidaemia.Jun 01, 2012

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2012 Jun ;107(12):1757-65. Epub 2011 Sep 29. PMID: 22017960

Article Published Date : Jun 01, 2012

Study Type : Animal Study

Additional Links

Substances : Coffee, Polyphenols

Diseases : Hyperglycemia, Hyperinsulinism, Hyperlipidemia

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Curcuma oil treatment significantly attenuated diabetic dyslipidaemia, insulin resistance and associated deleterious effects in HFr fed hamsters and rats. May 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Indian J Med Res. 2015 Jun ;141(6):823-32. PMID: 26205026

Article Published Date : May 31, 2015

Study Type : Animal Study

Additional Links

Substances : Turmeric

Diseases : Endothelial Dysfunction, High Fructose Diet, Hyperglycemia, Hyperinsulinism, Hyperlipidemia, Oxidative Stress

Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Natural Substances Versus Drugs

[+]

Curcumin reduces the adverse effects of hyperinsulinemia associated with type 2 diabetes by attenuating the effects of insulin on hepatic stellate cell activation and reducing oxidative stress. Jun 01, 2010

Click here to read the entire abstract

Pubmed Data : Clin Breast Cancer. 2010 Jun;10(3):224-9. PMID: 19841616

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Fatty Liver, Hepatic Steatosis, Hyperinsulinism, Liver Fibrosis

[+]

Ethanol acutely stimulates islet blood flow, amplifies insulin secretion, and induces hypoglycemia via nitric oxide and vagally mediated mechanisms.Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : Endocrinology. 2008 Jan;149(1):232-6. Epub 2007 Oct 4. PMID: 17916634

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Diseases : Hyperinsulinism, Hypoglycemia

Problem Substances : Ethanol

[+]

Exercise improves fructose-induced insulin resistance, hyperinsulinemia and hypertension.Aug 01, 1988

Click here to read the entire abstract

Pubmed Data : Hypertension. 1988 Aug;12(2):129-32. PMID: 3410522

Article Published Date : Aug 01, 1988

Study Type : Animal Study

Additional Links

Diseases : Fructose-Induced Toxicity , Hyperinsulinism, Hypertension, Insulin Resistance

Therapeutic Actions : Exercise

Problem Substances : Fructose

Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance, Hypertensive

[+]

Fiber attenuates weight gain, enhances insulin sensitivity, and modulates leptin and GLP-1 secretion and gastric ghrelin gene expressionDec 01, 2007

Click here to read the entire abstract

Pubmed Data : Metabolism. 2007 Dec;56(12):1635-42. PMID: 17998014

Article Published Date : Dec 01, 2007

Study Type : Animal Study

Additional Links

Substances : Fiber, Psyllium

Diseases : Hyperglycemia, Hyperinsulinism, Leptin: Elevated Levels, Overweight

Pharmacological Actions : Ghrelin Down-Regulation, Glucagon Like peptide 1 (GLP-1) Up-regulation, Hypoglycemic Agents, Insulin Down-Regulation

[+]

Fructose is used in an experimental model to induce metabolic syndrome. May 01, 2011

Click here to read the entire abstract

Pubmed Data : Acta Med Iran. 2011 May;49(5):277-83. PMID: 21713743

Article Published Date : May 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Cholesterol: LDL/HDL ratio, High Cholesterol: very low density lipoprotein (VLDL), Insulin: Elevated, Insulin Resistance, Metabolic Syndrome X, Triglycerides: Elevated

Problem Substances : Fructose

Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance

[+]

Fructose is used to induce hypertension in the animal model. Aug 01, 1989

Click here to read the entire abstract

Pubmed Data : Hypertension. 1989 Aug;14(2):117-20. PMID: 2569446

Article Published Date : Aug 01, 1989

Study Type : Animal Study

Additional Links

Diseases : Fructose-Induced Toxicity , Hypertension, Insulin: Elevated, Insulin Resistance

Problem Substances : Fructose

Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance, Hypertensive

[+]

Fructose is used to induced hyperinsulinemia, hypertriglyceridemia and hypertension in an animal moodel.Jun 01, 1989

Click here to read the entire abstract

Pubmed Data : Am J Hypertens. 1989 Jun;2(6 Pt 1):424-7. PMID: 2527043

Article Published Date : Jun 01, 1989

Study Type : Animal Study

Additional Links

Diseases : Fructose-Induced Toxicity , Hyperinsulinism, Hypertension, Triglycerides: Elevated

Problem Substances : Fructose

Adverse Pharmacological Actions : Dyslipidemic, Hypertensive

[+]

Fructose-fed animals develop hyperglycemia, hyperinsulinemia, hypertriglyceridemia and insulin resistance.Jun 24, 2011

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2011 Jun 24. Epub 2011 Jun 24. PMID: 21708140

Article Published Date : Jun 24, 2011

Study Type : Animal Study

Additional Links

Diseases : Hyperglycemia, Insulin: Elevated, Insulin Resistance, Triglycerides: Elevated

Problem Substances : Fructose

Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance

[+]

Fructose-induced hypertriglyceridemia is associated with significant hyperinsulinemia.Apr 01, 1980

Click here to read the entire abstract

Pubmed Data : Metabolism. 1980 Apr;29(4):303-5. PMID: 6990170

Article Published Date : Apr 01, 1980

Study Type : Animal Study

Additional Links

Diseases : Hyperinsulinism, Insulin: Elevated, Triglycerides: Elevated

Additional Keywords : Diseases that are Linked

Problem Substances : Fructose

Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance

[+]

Garlic improves insulin sensitivity and associated metabolic syndromes in fructose fed rats.Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Nutr Metab (Lond). 2011 ;8:53. Epub 2011 Jul 27. PMID: 21794123

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Fructose-Induced Toxicity , Hyperuricemia, Insulin: Elevated, Insulin Resistance, Metabolic Syndrome X, Triglycerides: Elevated

Pharmacological Actions : Insulin Sensitizers

Problem Substances : Fructose

Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance

[+]

Ginger has a beneficial effect on fructose induced hyperlipidemia an dhyperinsulinemia in rats. Dec 01, 2005

Click here to read the entire abstract

Pubmed Data : Indian J Exp Biol. 2005 Dec;43(12):1161-4. PMID: 16359128

Article Published Date : Dec 01, 2005

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : Fructose-Induced Toxicity , Hyperinsulinism, Hyperlipidemia, Metabolic Syndrome X

Additional Keywords : Plant Extracts

[+]

Gluten exorphin modulate pancreatic endocrine function by stimulating insulin release.Jan 01, 1995

Click here to read the entire abstract

Pubmed Data : Life Sci. 1995;57(7):729-34. PMID: 7637543

Article Published Date : Jan 01, 1995

Study Type : Animal Study

Additional Links

Diseases : Insulin: Elevated, Insulin Disorders

Problem Substances : Gluten exorphins

Adverse Pharmacological Actions : Endocrine Disruptor: Pancreas

[+]

Gluten exorphins have an effect on plasma insulin and glucagon levels in dogs.Apr 01, 1981

Click here to read the entire abstract

Pubmed Data : Diabetes. 1981 Apr ;30(4):362-4. PMID: 7009280

Article Published Date : Apr 01, 1981

Study Type : Animal Study

Additional Links

Diseases : Glucagon: Excess Secretion, Insulin: Elevated

Problem Substances : Gluten

Adverse Pharmacological Actions : Endocrine Disruptor, Endocrine Disruptor: Insulin Resistance

[+]

Gluten-free diet prevents diabetes in NOD mice.Aug 31, 1999

Click here to read the entire abstract

Pubmed Data : Diabetes Metab Res Rev. 1999 Sep-Oct;15(5):323-7. PMID: 10585617

Article Published Date : Aug 31, 1999

Study Type : Animal Study

Additional Links

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 1: Prevention, Hyperinsulinism

Problem Substances : Gliadin, Gluten

Adverse Pharmacological Actions : Diabetogenic, Immunotoxic

[+]

Grape seed proanthocyanidins is superior to metformin to promote insulin signaling in rats fed high calorie diet.Sep 11, 2013

Click here to read the entire abstract

Pubmed Data : J Cell Commun Signal. 2013 Sep 12. Epub 2013 Sep 12. PMID: 24026800

Article Published Date : Sep 11, 2013

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract, Proanthocyanidins

Diseases : Blood Sugar Problems, Diabetes Mellitus: Type 2, Hyperglycemia, Hyperinsulinism

Additional Keywords : Superiority of Natural Substances versus Drugs

Problem Substances : Metformin

[+]

Hypoglycemic effect of Opuntia ficus-indica var. saboten is due to enhanced peripheral glucose uptake.Dec 08, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2016 Dec 9 ;8(12). Epub 2016 Dec 9. PMID: 27941667

Article Published Date : Dec 08, 2016

Study Type : Animal Study

Additional Links

Substances : Prickly Pear Cactus

Diseases : Hyperglycemia, Hyperinsulinism, Insulin Resistance

Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents

Additional Keywords : Plant Extracts

[+]

Insulin may contribute to myopia. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Invest Ophthalmol Vis Sci. 2009 Jan;50(1):13-23. Epub 2008 Jul 3. PMID: 18599564

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Hyperinsulinism, Myopia

Additional Keywords : Diseases that are Linked

Problem Substances : Insulin

Adverse Pharmacological Actions : Myopiagenic

[+]

L-theanine suppresses food intake in rats, and may lower insulin levels.May 01, 2008

Click here to read the entire abstract

Pubmed Data : Biosci Biotechnol Biochem. 2008 May;72(5):1352-5. Epub 2008 May 7. PMID: 18460793

Article Published Date : May 01, 2008

Study Type : Animal Study

Additional Links

Substances : Theanine

Diseases : Appetite Disorders, Hyperinsulinism

[+]

Lactobacilluscasei Zhang administration exert both preventive and ameliorative effect on oral glucose tolerance.Jan 31, 2014

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2014 Feb ;53(1):221-32. PMID: 23797890

Article Published Date : Jan 31, 2014

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei

Diseases : Hyperinsulinism

Pharmacological Actions : Malondialdehyde Down-regulation

Additional Keywords : hyperinsulinism, Lactobacillus casei, Malondialdehyde Down-regulation

Problem Substances : Fructose

[+]

Litchi seeds have a wide range of benefits in insulin resistant rats with type 2 diabetes. Jun 01, 2004

Click here to read the entire abstract

Pubmed Data : Zhong Yao Cai. 2004 Jun;27(6):435-8. PMID: 15524300

Article Published Date : Jun 01, 2004

Study Type : Animal Study

Additional Links

Substances : Litchi

Diseases : Diabetes Mellitus: Type 2, Hyperinsulinism, Hyperleptinemia, Insulin Resistance

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Loquat improves hyperlipidemia and reverses insulin resistance in high-fat-fed mice.Dec 01, 2010

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2010 Dec;24(12):1769-80. PMID: 20564460

Article Published Date : Dec 01, 2010

Study Type : Animal Study

Additional Links

Substances : Loquat

Diseases : Hyperinsulinism, Hyperlipidemia, Insulin Resistance

Additional Keywords : Plant Extracts

[+]

Magnesium sulfate attenuates increased blood-brain barrier permeability during insulin-induced hypoglycemia in rats.Sep 01, 2001

Click here to read the entire abstract

Pubmed Data : Can J Physiol Pharmacol. 2001 Sep;79(9):793-8. PMID: 11599780

Article Published Date : Sep 01, 2001

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Blood-Brain-Barrier Disorders, Hyperinsulinism, Hypoglycemia

[+]

Mangiferin exhibits anti-diabetic properties.Mar 01, 2001

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2001 Mar;8(2):85-7. PMID: 11315760

Article Published Date : Mar 01, 2001

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Diabetes Mellitus: Type 2, Hyperglycemia, Hyperinsulinism, Insulin Resistance

Pharmacological Actions : Hypoglycemic Agents

Additional Keywords : Plant Extracts, Xanthones

[+]

Monosodium glutamate induces fatty liver, insulin and triglyceride elevations, increased weight gain and adverse liver changes.Aug 01, 2009

Click here to read the entire abstract

Pubmed Data : J Lipid Res. 2009 Aug;50(8):1521-37. Epub 2008 Nov 11. PMID: 19001666

Article Published Date : Aug 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Fatty Liver, Hyperinsulinism, Liver Damage, Triglycerides: Elevated, Weight Problems

Problem Substances : Insulin , Monosodium Glutamate (MSG), Trans Fatty Acids

[+]

Nigella sativa (black cumin) protects against chronic antiretroviral therapy-associated insulin resistance in HIV-1 infected rats. Apr 01, 2009

Click here to read the entire abstract

Pubmed Data : Can J Physiol Pharmacol. 2009 Apr;87(4):300-9. PMID: 19370083

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : HIV Drug-Induced Toxicity , Hyperinsulinism

Pharmacological Actions : Antioxidants

Additional Keywords : Drug Side Effect Attenuation

[+]

Nigella sativa oil and chromium picolinate monotherapy can reduce fructose-induced insulin resistance.Oct 03, 2017

Click here to read the entire abstract

Pubmed Data : Biol Trace Elem Res. 2017 Oct 4. Epub 2017 Oct 4. PMID: 28975521

Article Published Date : Oct 03, 2017

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : High Fructose Diet, Hyperinsulinism

Pharmacological Actions : Insulin Sensitizers

[+]

Protective effect of vanillic acid against hyperinsulinemia, hyperglycemia and hyperlipidemia.Dec 01, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2015 Dec 2 ;7(12):9946-59. Epub 2015 Dec 2. PMID: 26633482

Article Published Date : Dec 01, 2015

Study Type : Animal Study

Additional Links

Substances : Vanillic Acid

Diseases : Hyperinsulinism, Hyperlipidemia, Inflammation, Insulin Resistance

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Insulin Sensitizers, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Red grape berry-cultured cells reduce blood pressure in rats with metabolic-like syndrome.Mar 31, 2014

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2014 Apr ;53(3):973-80. Epub 2013 Oct 26. PMID: 24158651

Article Published Date : Mar 31, 2014

Study Type : Animal Study

Additional Links

Substances : Grape

Diseases : Hyperinsulinism, Hypertension

Pharmacological Actions : Antihypertensive Agents

Additional Keywords : Plant Extracts

[+]

Ursolic acid demonstrated its potential therapeutic utility to improve IR, hyperinsulinemia, and inflammation observed in obesity and diabetes.Nov 19, 2019

Click here to read the entire abstract

Pubmed Data : J Med Food. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31747348

Article Published Date : Nov 19, 2019

Study Type : Animal Study

Additional Links

Substances : Ursolic Acid

Diseases : Hyperinsulinism, Insulin Resistance, Obesity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Vanadyl sulfate ameliorates insulin resistance and restores plasma dehydroepiandrosterone-sulfate levels in fructose-fed, insulin-resistant rats.Aug 01, 2004

Click here to read the entire abstract

Pubmed Data : Clin Biochem. 2004 Aug;37(8):694-7. PMID: 15302613

Article Published Date : Aug 01, 2004

Study Type : Animal Study

Additional Links

Substances : Vanadyl Sulfate

Diseases : DHEA: Low, Fructose-Induced Toxicity , Hyperinsulinism, Insulin Resistance

Problem Substances : Fructose

[+]

Yerba mate has a protective effect against a high-fat diet induced obesity in rats through significantly lowering body weight, visceral fat, blood and liver lipids, glucose, insulin and leptin levels. Aug 15, 2008

Click here to read the entire abstract

Pubmed Data : Arch Biochem Biophys. 2008 Aug 15;476(2):178-85. Epub 2008 Feb 26. PMID: 18314006

Article Published Date : Aug 15, 2008

Study Type : Animal Study

Additional Links

Substances : Yerba Mate

Diseases : Abdominal Obesity (Midsection Fat), Hyperinsulinism, Leptin: Elevated Levels, Obesity

[+]

"Milk--the promoter of chronic Western diseases." Jun 01, 2009

Click here to read the entire abstract

Pubmed Data : Med Hypotheses. 2009 Jun ;72(6):631-9. Epub 2009 Feb 15. PMID: 19232475

Article Published Date : Jun 01, 2009

Study Type : Commentary

Additional Links

Diseases : Acne, Allergy: Cow's Milk , Atherosclerosis, Casein Intolerance, Diabetes Mellitus: Type 1, Hyperinsulinism, Insulin-like Growth Factor (IGF): Elevated, Neurodegenerative Diseases, Obesity

Problem Substances : Cow Milk

[+]

"Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization."Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Nutr Metab (Lond). 2011 ;8:41. Epub 2011 Jun 24. PMID: 21699736

Article Published Date : Jan 01, 2011

Study Type : Review

Additional Links

Diseases : Acne, Cancers: All, Diabetes Mellitus: Type 1, Hyperinsulinism, Insulin: Elevated

Anti Therapeutic Actions : Western Diet

Problem Substances : Cow Milk, Insulin

Adverse Pharmacological Actions : Insulinotropic

[+]

Flavonoids are capable of inhibiting insulin-stimulated glucose uptake in fat cells. Jan 01, 2004

Click here to read the entire abstract

Pubmed Data : J Med Food. 2004;7(1):38-44. PMID: 18591783

Article Published Date : Jan 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Apigenin, Fisetin, Flavonoids, Kaempferol, Luteolin, Quercetin

Diseases : Hyperinsulinism, Obesity, Weight Problems

Pharmacological Actions : Hypoglycemic Agents

[+]

Raisins have the potential to significantly reduce the risk for developing diabetes or cardiovascular disease.May 31, 2013

Click here to read the entire abstract

Pubmed Data : J Food Sci. 2013 Jun ;78 Suppl 1:A11-7. PMID: 23789931

Article Published Date : May 31, 2013

Study Type : Review

Additional Links

Substances : Raisins

Diseases : Cardiovascular Diseases, Hyperinsulinism

Pharmacological Actions : Antihypertensive Agents, Cardioprotective, Hypolipidemic

Additional Keywords : Risk Reduction

[+]

The artificial sweeteners sodium cyclamate, aspartame, acesulfame potassium, and saccharin have insulin-releasing action on pancreatic beta cells. Nov 01, 1998

Click here to read the entire abstract

Pubmed Data : Cell Signal. 1998 Nov;10(10):727-33. PMID: 9884024

Article Published Date : Nov 01, 1998

Study Type : In Vitro Study

Additional Links

Diseases : Hyperinsulinism

Problem Substances : Acesulfame potassium , Artificial Sweeteners, Saccharin, Sodium Cyclamate

[+]

Vanillic acid mitigates the impairments in glucose metabolism in HepG2 cells through BAD-GK interaction during hyperinsulinemia.May 31, 2021

Click here to read the entire abstract

Pubmed Data : J Biochem Mol Toxicol. 2021 Jun ;35(6):1-8. Epub 2021 Mar 2. PMID: 33651899

Article Published Date : May 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Vanillic Acid

Diseases : Hyperinsulinism

[+]

Wheat germ agglutinin (WGA) and concanavalin A exhibit insulin-mimetic properties.Apr 01, 1987

Click here to read the entire abstract

Pubmed Data : Arch Biochem Biophys. 1987 Apr;254(1):110-5. PMID: 3555340

Article Published Date : Apr 01, 1987

Study Type : In Vitro Study

Additional Links

Diseases : Hyperinsulinism, Insulin Disorders, Insulin Resistance

Additional Keywords : Insulin Mimetic

Problem Substances : Concanavalin A, Wheat Germ Agglutinin (WGA)

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View the Evidence: 73 Abstracts with Hyperinsulinism Research

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Meta-analysis: Chocolate, cocoa and flavan-3-ols improve insulin resistance, reduces serum insulin levels, and parameters associated with cardiovascular disease risk. Feb 01, 2012

After 4 weeks consuming broccoli sprouts powder it resulted in a significant decrease in serum insulin concentration in patients. Oct 31, 2012

Almonds reduce insulin secretion and insulin resistance in nondiabetic hyperlipidemic subjects. Jul 01, 2008

Berries reduce postprandial insulin responses to wheat and rye breads in healthy women.Mar 31, 2013

Caloric restriction ameliorates defective insulin binding to receptors in obese men. Jan 01, 1975

Clamping cortisol and testosterone mitigates the development of insulin resistance during sleep restriction in men.Aug 17, 2021

Controlled-release alpha lipoic acid has a therapeutic effect in lean, nondiabetic patients with polycystic ovary syndrome.Mar 01, 2010

Four grams of high molecular weight oat β-glucan lowers appetite but not ad libitum eating and beneficially modulates postprandial glycemia.Jan 01, 2018

Higher insulin concentrations, as well as the presence of insulin resistance, appear to be associated with an elevated risk of lung cancer development.Jul 10, 2017

In patients with METS, phlebotomy, with consecutive reduction of body iron stores, lowered BP and resulted in improvements in markers of cardiovascular risk and glycemic control.Dec 31, 2011

Insulinemic and inflammatory dietary patterns and risk of prostate cancer. Jan 05, 2021

Orange pomace fiber lowers postprandial glycemic and insulinemic responses in men with increased cardiometabolic risk.Jan 01, 2016

Postmeal fluctuations in blood glucose and insulin induced by sucrose are alleviated when sucrose is consumed with blackcurrants or lingonberries. Aug 31, 2012

Pre-exercise carbohydrate ingestion after a 4-hour fast is sufficient to induce a transient hypoglycemia.May 01, 1999

Regular consumption of chili may attenuate postprandial hyperinsulinemia.Jul 01, 2006

Substituting saturated fats with monounsaturated fats within high-fat diets attenuates hyperinsulinemia and pancreatic islet dysfunction.Mar 03, 2020

The Chinese herbal formula "tiangui fang" may have value in the treatment of hyperandrogenism and hyperinsulinism in polycystic ovary syndrome.Aug 01, 2000

The consumption of sugar-sweetened beverages was associated with higher concentrations of insulin and leptin and a higher HOMA-IR.Jun 30, 2014

Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects.Sep 01, 2005

Walnuts may improve metabolic parameters in type II diabetes.Aug 01, 2009

Wheat fiber supplementation increases GLP-1 secretion and improves colonic fermentation by-products in hyperinsulinemic patients. Jan 01, 2010

Whole grain and bran from rye resulted in significantly lower plasma PSA in patients with prostate cancer.Dec 01, 2010

The ketogenic diet could represent an effective treatment to support brain function in selected cases of congenital hyperinsulinism.Dec 31, 2014

"Brain insulin impairs amyloid-beta(1-40) clearance from the brain."Oct 26, 2004

A combination of black seeds and turmeric at low doses showed enhanced efficacy in preventing metabolic syndrome in fructose fed rats.Jan 31, 2015

A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats.Jan 01, 2012

A water extract of maitake mushroom reduces circulating glucose/insulin concentrations in insulin-resistant mice. Jan 01, 2002

Acesulfame K acts directly on the pancreatic islets and potentiates glucose-induced insulin release.Jul 01, 1987

Acesulfame stimulates insulin secretion. Jun 01, 1987

An anthocyanin-rich Kamchatka honeysuckle berry extract supplemented to an unbalanced diet is able to ameliorate disturbances in lipid/glucose metabolism that are risk factors for CVD and diabetes.May 31, 2013

Aspartame exposure may promote hyperglycemia and insulin intolerance. MSG may interact with aspartame to further impair glucose homeostasis.Jun 14, 2012

Baicalin suppresses body weight gain, visceral fat mass, serum cholesterol, free fatty acid and insulin concentrations caused by a high-fat diet. Nov 01, 2009

Coffee polyphenols modulate whole-body substrate oxidation and suppress postprandial hyperglycaemia, hyperinsulinaemia and hyperlipidaemia.Jun 01, 2012

Coffee polyphenols modulate whole-body substrate oxidation and suppress postprandial hyperglycaemia, hyperinsulinaemia and hyperlipidaemia.Jun 01, 2012

Curcuma oil treatment significantly attenuated diabetic dyslipidaemia, insulin resistance and associated deleterious effects in HFr fed hamsters and rats. May 31, 2015

Curcumin reduces the adverse effects of hyperinsulinemia associated with type 2 diabetes by attenuating the effects of insulin on hepatic stellate cell activation and reducing oxidative stress. Jun 01, 2010

Ethanol acutely stimulates islet blood flow, amplifies insulin secretion, and induces hypoglycemia via nitric oxide and vagally mediated mechanisms.Jan 01, 2008

Exercise improves fructose-induced insulin resistance, hyperinsulinemia and hypertension.Aug 01, 1988

Fiber attenuates weight gain, enhances insulin sensitivity, and modulates leptin and GLP-1 secretion and gastric ghrelin gene expressionDec 01, 2007

Fructose is used in an experimental model to induce metabolic syndrome. May 01, 2011

Fructose is used to induce hypertension in the animal model. Aug 01, 1989

Fructose is used to induced hyperinsulinemia, hypertriglyceridemia and hypertension in an animal moodel.Jun 01, 1989

Fructose-fed animals develop hyperglycemia, hyperinsulinemia, hypertriglyceridemia and insulin resistance.Jun 24, 2011

Fructose-induced hypertriglyceridemia is associated with significant hyperinsulinemia.Apr 01, 1980

Garlic improves insulin sensitivity and associated metabolic syndromes in fructose fed rats.Jan 01, 2011

Ginger has a beneficial effect on fructose induced hyperlipidemia an dhyperinsulinemia in rats. Dec 01, 2005

Gluten exorphin modulate pancreatic endocrine function by stimulating insulin release.Jan 01, 1995

Gluten exorphins have an effect on plasma insulin and glucagon levels in dogs.Apr 01, 1981

Gluten-free diet prevents diabetes in NOD mice.Aug 31, 1999

Grape seed proanthocyanidins is superior to metformin to promote insulin signaling in rats fed high calorie diet.Sep 11, 2013

Hypoglycemic effect of Opuntia ficus-indica var. saboten is due to enhanced peripheral glucose uptake.Dec 08, 2016

Insulin may contribute to myopia. Jan 01, 2009

L-theanine suppresses food intake in rats, and may lower insulin levels.May 01, 2008

Lactobacilluscasei Zhang administration exert both preventive and ameliorative effect on oral glucose tolerance.Jan 31, 2014

Litchi seeds have a wide range of benefits in insulin resistant rats with type 2 diabetes. Jun 01, 2004

Loquat improves hyperlipidemia and reverses insulin resistance in high-fat-fed mice.Dec 01, 2010

Magnesium sulfate attenuates increased blood-brain barrier permeability during insulin-induced hypoglycemia in rats.Sep 01, 2001

Mangiferin exhibits anti-diabetic properties.Mar 01, 2001

Monosodium glutamate induces fatty liver, insulin and triglyceride elevations, increased weight gain and adverse liver changes.Aug 01, 2009

Nigella sativa (black cumin) protects against chronic antiretroviral therapy-associated insulin resistance in HIV-1 infected rats. Apr 01, 2009

Nigella sativa oil and chromium picolinate monotherapy can reduce fructose-induced insulin resistance.Oct 03, 2017

Protective effect of vanillic acid against hyperinsulinemia, hyperglycemia and hyperlipidemia.Dec 01, 2015

Red grape berry-cultured cells reduce blood pressure in rats with metabolic-like syndrome.Mar 31, 2014

Ursolic acid demonstrated its potential therapeutic utility to improve IR, hyperinsulinemia, and inflammation observed in obesity and diabetes.Nov 19, 2019

Vanadyl sulfate ameliorates insulin resistance and restores plasma dehydroepiandrosterone-sulfate levels in fructose-fed, insulin-resistant rats.Aug 01, 2004

Yerba mate has a protective effect against a high-fat diet induced obesity in rats through significantly lowering body weight, visceral fat, blood and liver lipids, glucose, insulin and leptin levels. Aug 15, 2008

"Milk--the promoter of chronic Western diseases." Jun 01, 2009

"Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization."Jan 01, 2011

Flavonoids are capable of inhibiting insulin-stimulated glucose uptake in fat cells. Jan 01, 2004

Raisins have the potential to significantly reduce the risk for developing diabetes or cardiovascular disease.May 31, 2013

The artificial sweeteners sodium cyclamate, aspartame, acesulfame potassium, and saccharin have insulin-releasing action on pancreatic beta cells. Nov 01, 1998

Vanillic acid mitigates the impairments in glucose metabolism in HepG2 cells through BAD-GK interaction during hyperinsulinemia.May 31, 2021

Hyperinsulinism

View the Evidence:
73 Abstracts with Hyperinsulinism Research