Immune Dysregulation: TH1/TH2 imbalance

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55 Substances Researched for Immune Dysregulation: TH1/TH2 imbalance
NameACCKFocus
Probiotics321Locked
Beta-glucan212Locked
Fucoidan212Locked
Lactobacillus probiotics212Locked
Astragalus110Locked
Bifidobacterium Infantis110Locked
Lactobacillus paracasei110Locked
Lactobacillus salivarius 110Locked
Theanine110Locked
Curcumin36Locked
Maitake Mushroom35Locked
Agaricus Blazei12Locked
Amaranth 12Locked
Apigenin12Locked
Bamboo12Locked
Brown Rice12Locked
Chinese Skullcap 12Locked
Chlorella (Algae)12Locked
D-Pinitol12Locked
Ferulic acid12Locked
Garlic12Locked
Geraniol 12Locked
Ginkgo biloba12Locked
Hydrogen Water12Locked
Kaempferol12Locked
Lactobacillus reuteri12Locked
Ligusticum wallichii 12Locked
Loquat12Locked
Loquat Seeds12Locked
NAC (N-acetyl-L-cysteine)12Locked
Oleanolic acid12Locked
Paeoniflorin12Locked
Pine Bark Extract12Locked
Prickly Pear Cactus12Locked
Quercetin12Locked
Resveratrol12Locked
Rose 12Locked
Selenium12Locked
Sulforaphane12Locked
Turmeric12Locked
Vitamin D12Locked
Xanthohumol12Locked
Zerumbone12Locked
Arnica11Locked
Cannabinoids 11Locked
Cordyceps sinensis11Locked
Crocetin11Locked
Delta-tetrahydrocannabinol (THC)11Locked
EPA (Eicosapentaenoic Acid)11Locked
Ginsenosides11Locked
Helenalin11Locked
Papaya11Locked
Purslane11Locked
Safranal11Locked
Spirulina11Locked
9 Problem Substances Researched for Immune Dysregulation: TH1/TH2 imbalance
NameACCKFocus
Adjuvant211Locked
Aluminum Hydroxide110Locked
Infant Formula110Locked
Vaccine Adjuvants110Locked
Dexamethasone12Locked
Lead12Locked
Lovastatin12Locked
Statin Drugs12Locked
Bisphenol A 11Locked
2 Therapeutic Actions Researched for Immune Dysregulation: TH1/TH2 imbalance
NameACCKFocus
Electroacupuncture110Locked
Exercise110Locked
5 Problematic Actions Researched for Immune Dysregulation: TH1/TH2 imbalance
NameACCKFocus
Vaccination: Diphtheria-Pertussis-Tetanus220Locked
Vaccination: All211Locked
Vaccination: Pertussis110Locked
Vaccination: Tetanus110Locked
Vaccinaton: Diptheria110Locked

View the Evidence:
66 Abstracts with Immune Dysregulation: TH1/TH2 imbalance Research

[+]

Astragalus improves immune function in Herpes Simplex Keratitis.Jun 01, 2007

Pubmed Data : Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1906-16. Epub 2007 Mar 6 PMID: 15015443
Article Published Date : Jun 01, 2007
Study Type : Human Study
Additional Links
Substances : Astragalus
Diseases : Herpes: Keratitis, Herpes family viruses, Immune Dysregulation: TH1/TH2 imbalance, Keratitis
[+]

B infantis 35624 alleviates symptoms in IBS; this symptomatic response was associated with normalization of the ratio of an anti-inflammatory to a proinflammatory cytokine, suggesting an immune-modulating role for this organism, in this disorder.Mar 01, 2005

Pubmed Data : Gastroenterology. 2005 Mar;128(3):541-51. PMID: 15765388
Article Published Date : Mar 01, 2005
Study Type : Human Study
Additional Links
Substances : Bifidobacterium Infantis
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Irritable Bowel Syndrome
Pharmacological Actions : Immunomodulatory
[+]

Beta-glucan improves symptoms and the Th1/Th2 balance in patients with allergic rhinitisJun 01, 2005

Pubmed Data : Eur Cytokine Netw. 2005 Jun;16(2):128-34. PMID: 15941684
Article Published Date : Jun 01, 2005
Study Type : Human Study
Additional Links
Substances : Beta-glucan
Diseases : Allergic Rhinitis, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Interleukin-12 upregulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Electroacupuncture is superior to fluoxetine (Prozac) in improving the TH1/TH2 cytokine ratios in depressed patients. Sep 01, 2009

Pubmed Data : Pharmacopsychiatry. 2009 Sep;42(5):182-8. Epub 2009 Sep 1. PMID: 19724980
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Diseases : Depression, Immune Dysregulation: TH1/TH2 imbalance
Therapeutic Actions : Electroacupuncture
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Formula feeding skews immune cell composition toward adaptive immunity compared to breastfeeding.Oct 01, 2009

Pubmed Data : J Immunol. 2009 Oct 1;183(7):4322-8. Epub 2009 Sep 4. PMID: 19734215
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Problem Substances : Infant Formula
[+]

Oligo-fucoidan improved unbalance the Th1/Th2 and Treg/Th17 ratios in asthmatic patients.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Jan ;17(1):3-10. Epub 2018 Nov 7. PMID: 30651758
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Fucoidan
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

Probiotics demonstrate immunomodulatory effects in atopic pediatric patients by increasing the TH1 immune response which counterbalances the dominant TH2 immune response. Jul 01, 2008

Pubmed Data : Pediatr Med Chir. 2008 Jul-Aug;30(4):197-203. PMID: 19216203
Article Published Date : Jul 01, 2008
Study Type : Human Study
Additional Links
Substances : Lactobacillus paracasei, Lactobacillus probiotics, Lactobacillus salivarius , Probiotics
Diseases : Atopic Disease, Immune Dysregulation: TH1/TH2 imbalance
[+]

Probiotics reduce the incidence of eczema in infants. Aug 01, 2009

Pubmed Data : Pediatr Allergy Immunol. 2009 Aug;20(5):430-7. Epub 2009 Mar 9. PMID: 19298231
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Eczema, Eczema: Infant, Immune Dysregulation: TH1/TH2 imbalance
[+]

Recreational music-making (drumming) modulates natural killer cell activity, cytokines, and mood states in corporate employees.Sep 01, 2005

Pubmed Data : Biol Pharm Bull. 2005 Sep;28(9):1766-9. PMID: 17261984
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Diseases : Immune Disorders: Low Immune Function, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Supplementation with L-theanine seems to exert a beneficial effect on a disrupted Th1/Th2 balance in elite athletes.Feb 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Int Soc Sports Nutr. 2019 Feb 15 ;16(1):7. Epub 2019 Feb 15. PMID: 30770758
Article Published Date : Feb 14, 2019
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Athletic Performance, Immune Dysregulation: TH1/TH2 imbalance
Therapeutic Actions : Exercise
Pharmacological Actions : Immunomodulatory, Interleukin-10 downregulation
[+]

The association with DTwP vaccines and increased infant mortality in females may be due to vaccine adjuvants and Th2 polarizing effects.Jan 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Trop Med. 2011 ;2011:706304. Epub 2011 May 5. PMID: 21760811
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Infant Mortality , Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis, Vaccination: Tetanus, Vaccinaton: Diptheria
Problem Substances : Adjuvant, Aluminum Hydroxide, Vaccine Adjuvants
[+]

The elimination diet in infants with food allergy associated eczema results in improvement in immunoregulation and symptoms.Jun 01, 2010

Pubmed Data : Pediatr Allergy Immunol. 2010 Jun;21(4 Pt 1):649-55. PMID: 20636896
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Diseases : Eczema: Infant, Food Allergies, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Timing of routine immunisations (earlier = increased) and subsequent hay fever risk.May 31, 2005

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Dis Child. 2005 Jun ;90(6):567-73. PMID: 15908618
Article Published Date : May 31, 2005
Study Type : Human Study
Additional Links
Diseases : Allergic Rhinitis, Immune Dysregulation: TH1/TH2 imbalance, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus
[+]

A polysaccharide, extract from Maitake, induces Th-1 dominant responses in cancer-bearing mice. Dec 01, 2002

Pubmed Data : Jpn J Pharmacol. 2002 Dec;90(4):357-60. PMID: 12501013
Article Published Date : Dec 01, 2002
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

A sulfated polysaccharide, fucoidan, enhances the immunomodulatory effects of lactic acid bacteria.Feb 29, 2012

Pubmed Data : Int J Mol Med. 2012 Mar ;29(3):447-53. Epub 2011 Dec 5. PMID: 22160132
Article Published Date : Feb 29, 2012
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
Additional Keywords : Natural Substance Synergy
[+]

An extract of the medicinal mushroom Agaricus blazei Murill can protect against allergy through reducing Th2 relative to Th1 cytokine levels. Jan 01, 2009

Pubmed Data : Clin Mol Allergy. 2009;7:6. Epub 2009 May 5. PMID: 19416507
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Agaricus Blazei
Diseases : Allergies, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Anti-inflammatory, antioxidant, and immunomodulatory effects of curcumin in ovalbumin-sensitized rat.Jul 07, 2017

Pubmed Data : Biofactors. 2017 Jul 8 ;43(4):567-576. Epub 2017 May 16. PMID: 28509396
Article Published Date : Jul 07, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory
[+]

Apigenin administration effectively ameliorated autoimmune myocarditis-induced cardiac hypertrophy and cardiac dysfunctionDec 10, 2015

Pubmed Data : Inflammation. 2015 Dec 11. Epub 2015 Dec 11. PMID: 26658748
Article Published Date : Dec 10, 2015
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Myocarditis: Autoimmune
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 downregulation, Interleukin-2 Downregulation, Interleukin-4 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Autism is associated with dysregulation of transcription factor signalling that can be corrected by resveratrol treatment in mice. Aug 29, 2016

Pubmed Data : Mol Neurobiol. 2016 Aug 30. Epub 2016 Aug 30. PMID: 27578011
Article Published Date : Aug 29, 2016
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Autism, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory: Th17 downregulation, MicroRNA modulator
[+]

Bamboo extract reduces ovalbumin-induced airway inflammation and T helper 2 responses in mice.Mar 02, 2010

Pubmed Data : J Ethnopharmacol. 2010 Mar 2;128(1):241-7. Epub 2010 Jan 14. PMID: 20079411
Article Published Date : Mar 02, 2010
Study Type : Animal Study
Additional Links
Substances : Bamboo
Diseases : Allergic Airway Diseases, Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Allergic Agents
Additional Keywords : Plant Extracts
[+]

Beta glucan inhibits experimental periodontal disease possibly through steering the T helper Th1/Th2 balance towards Th1 and T regulatory responses. Apr 01, 2005

Pubmed Data : J Clin Periodontol. 2005 Apr;32(4):347-52. PMID: 15811050
Article Published Date : Apr 01, 2005
Study Type : Animal Study
Additional Links
Substances : Beta-glucan
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Lipopolysaccharide-Induced Toxicity, Periodontal Diseases
Pharmacological Actions : Immunomodulatory, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chinese skullcap contains a compound, Baicalin, which may favorably alter the TH1/TH2 balance in asthma. Sep 01, 2009

Pubmed Data : Zhong Yao Cai. 2009 Sep;32(9):1407-10. PMID: 20034219
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Chlorella reduces the IgE production against milk casein in mice. May 01, 1999

Pubmed Data : Int J Immunopharmacol. 1999 May;21(5):311-23. PMID: 10408628
Article Published Date : May 01, 1999
Study Type : Animal Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Allergy: Cow's Milk , Immune Dysregulation: TH1/TH2 imbalance
[+]

Curcumin induces a tolerogenic response in an animal model of colitis. Nov 01, 2009

Pubmed Data : Eur J Immunol. 2009 Nov;39(11):3134-46. PMID: 19839007
Article Published Date : Nov 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Colitis, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts.Jul 01, 2010

Pubmed Data : Cell Mol Immunol. 2010 Jul;7(4):306-15. Epub 2010 Mar 22. PMID: 20305684
Article Published Date : Jul 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Tumors
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Interleukin-10 downregulation
[+]

D-pinitol regulates Th1/Th2 balance via suppressing Th2 immune response in ovalbumin-induced asthma.Jan 09, 2007

Pubmed Data : FEBS Lett. 2007 Jan 9;581(1):57-64. Epub 2006 Dec 11. PMID: 17174308
Article Published Date : Jan 09, 2007
Study Type : Animal Study
Additional Links
Substances : D-Pinitol
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
[+]

Dietary amaranths modulate the immune response via balancing Th1/Th2 and Th17/Treg response in collagen-induced arthritis,Aug 31, 2020

Pubmed Data : Mol Cell Biochem. 2020 Sep ;472(1-2):57-66. Epub 2020 Jun 11. PMID: 32529499
Article Published Date : Aug 31, 2020
Study Type : Animal Study
Additional Links
Substances : Amaranth
Diseases : Arthritis, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Eriobotrya japonica may have beneficial immunomodulatory effects, improving the balance of Th1/Th2 cytokines and anti-inflammatory effects.Jan 31, 2016

Pubmed Data : Immunol Invest. 2016 Feb ;45(2):148-60. Epub 2016 Feb 8. PMID: 26854821
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Loquat
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Immunologic Deficiency Syndromes, Murine Leukemia Virus
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Ferulic acid exhibits an antiallergic effect via restoring Th1/Th2 imbalance by modulating dendritic cells function in an asthmatic mouse model.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:678487. Epub 2015 Oct 1. PMID: 26495021
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Ferulic acid
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance, Inflammation
Pharmacological Actions : Anti-Allergic Agents, Immunomodulatory
[+]

Garlic contains a compound known as allitridin which may combat cytomegalovirus infection by positively altering the Th1/Th2 balance towards Th1 balance in the infected host. Jan 01, 2005

Pubmed Data : J Med Food. 2005;8(3):332-6. PMID: 16176143
Article Published Date : Jan 01, 2005
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
Additional Keywords : Allitridin
[+]

Geraniol attenuated important features of allergic asthma in mice.May 31, 2016

Pubmed Data : Ann Allergy Asthma Immunol. 2016 Jun ;116(6):506-13. Epub 2016 Apr 22. PMID: 27117312
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Geraniol
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Antioxidants, Immunomodulatory, Nrf2 activation, Superoxide Dismutase Up-regulation
[+]

Hydrogen-rich saline ameliorates allergic rhinitis by reversing the imbalance of Th1/Th2 and up-regulation of CD4+CD25+Foxp3+regulatory T cells.Jan 31, 2018

Pubmed Data : Inflammation. 2018 Feb ;41(1):81-92. PMID: 28894978
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Allergic Rhinitis, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation
[+]

Kaempferol downregulates TH2 cytokine production without inducing a TH1 pattern of inflammation in a manner that may have potential clinical use for the treatment of allergic asthma. Sep 12, 2009

Pubmed Data : Int Immunopharmacol. 2009 Sep 12. PMID: 19755174
Article Published Date : Sep 12, 2009
Study Type : Animal Study
Additional Links
Substances : Kaempferol
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
[+]

Lactobacillus reuteri has an immuno-regulatory action in attentuating asthmatic response in a mouse model of allergic airway inflammation.Nov 21, 2008

Pubmed Data : Am J Respir Crit Care Med. 2008 Nov 21. PMID: 19029003
Article Published Date : Nov 21, 2008
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Allergies, Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Ligustrazine, an alkaloid found within Ligusticum, inhibits airway inflammatory cell infiltration by reverseing the TH2 cytokine patterns in asthma. Jan 01, 2007

Pubmed Data : Am J Chin Med. 2007;35(6):1011-20. PMID: 18186587
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Ligusticum wallichii
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-4 downregulation
[+]

Loquat seed has immunomodulatory properties in allergic dermatitis. Jan 01, 2010

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2010;56(2):145-9. PMID: 20495297
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Loquat Seeds
Diseases : Allergies, Dermatitis, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Allergic Agents, Immunomodulatory, Interferon-gamma (IFN-gamma) inducer, Interleukin-10 upregulation, Interleukin-2 upregulation, Interleukin-4 downregulation
Additional Keywords : Plant Extracts
[+]

Lovastatin alters the immunological balance towards a Th2 dominant state.Nov 29, 2002

Pubmed Data : Neurosci Lett. 2002 Nov 29 ;333(3):167-70. PMID: 12429374
Article Published Date : Nov 29, 2002
Study Type : Animal Study
Additional Links
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Interleukin-10 downregulation, Interleukin-6 Downregulation
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Immunoreactive
[+]

Maitake expresses anti-tumor effects by establishing a helper (TH)-1 dominance in mice. Mar 31, 2003

Pubmed Data : Cancer Lett. 2003 Mar 31;192(2):181-7. PMID: 12668282
Article Published Date : Mar 31, 2003
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Tumor, Immunomodulatory
[+]

O. humifusa is a potential anti-asthmatic functional food.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2017 ;61(1):1393307. Epub 2017 Oct 24. PMID: 29151835
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Asthmatic Agents, Immunomodulatory
[+]

Oleanolic acid reduces the severity and development of autoimmune encephalomyelitis and improves the TH1/TH2 polarization in an experimental model of multiple sclerosis. Jan 01, 2009

Pubmed Data : Physiol Res. 2009;58(4):511-9. Epub 2008 Jul 25. PMID: 19679109
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Oleanolic acid
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Multiple Sclerosis
[+]

Oryza sativa (brown rice) extract slows the progression of airway inflammation and remodeling in an experimental animal model of asthma.Apr 01, 2006

Pubmed Data : Planta Med. 2006 Apr;72(5):405-10. PMID: 16557453
Article Published Date : Apr 01, 2006
Study Type : Animal Study
Additional Links
Substances : Brown Rice
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Additional Keywords : Plant Extracts
[+]

Paeoniflorin may effectively ameliorate the progression of asthma.Nov 30, 2015

Pubmed Data : Inflammation. 2015 Dec ;38(6):2017-25. PMID: 25971794
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Asthmatic Agents, Immunomodulatory, Interleukin-4 downregulation
Additional Keywords : Phytotherapy
Problem Substances : Dexamethasone
[+]

Pinus densiflora bark extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis.Feb 26, 2018

Pubmed Data : Phytother Res. 2018 Feb 27. Epub 2018 Feb 27. PMID: 29484729
Article Published Date : Feb 26, 2018
Study Type : Animal Study
Additional Links
Substances : Pine Bark Extract
Diseases : Atopic Dermatitis, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Quercetin regulates Th1/Th2 balance in a murine model of asthma.Mar 01, 2009

Pubmed Data : Int Immunopharmacol. 2009 Mar;9(3):261-7. Epub 2008 Dec 4. PMID: 19061976
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Antioxidants, Interleukin-4 downregulation
[+]

Rosae Multiflorae fructus extract may have therapeutic potential for treating allergic rhinitis by modulating the relationships between Th1/Th2 responses.Feb 28, 2019

Pubmed Data : Phytomedicine. 2019 Mar 1 ;55:238-248. Epub 2018 Aug 11. PMID: 30668435
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Rose
Diseases : Allergic Rhinitis, Immune Dysregulation: TH1/TH2 imbalance, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
Additional Keywords : Plant Extracts
[+]

Selenium can alleviate the toxic effects caused by lead in the peripheral blood lymphocytes.Jul 14, 2019

Pubmed Data : Ecotoxicol Environ Saf. 2019 Jul 15 ;175:74-82. Epub 2019 Mar 16. PMID: 30889402
Article Published Date : Jul 14, 2019
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
Problem Substances : Lead
[+]

Sulforaphane and NAC (N-acetyl-L-cysteine) upregulate T(H)1 immunity in aging.May 01, 2008

Pubmed Data : J Allergy Clin Immunol. 2008 May;121(5):1255-1261.e7. Epub 2008 Mar 5. PMID: 18325578
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine), Sulforaphane
Diseases : Aging, Immune Disorders: Low Immune Function, Immune Dysregulation: TH1/TH2 imbalance, Low Disorders: Low TH1
Pharmacological Actions : Antioxidants, Immunomodulatory
[+]

The present study indicates that the immunomodulatory effects of Lactobacilli might be strain-dependent.Feb 29, 2016

Pubmed Data : Sichuan Da Xue Xue Bao Yi Xue Ban. 2016 Mar ;47(2):192-6. PMID: 27263293
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Lactobacillus probiotics
Diseases : Allergies, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Allergic Agents, Immunomodulatory, Interleukin-6 Downregulation
[+]

The therapeutic potential of ginkgolide K in experimental autoimmune encephalomyelitis via peripheral immunomodulation.Apr 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 May ;70:284-294. Epub 2019 Mar 6. PMID: 30851709
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

Turmeric ameliorated OVA-induced food allergy by maintaining Th1/Th2 balance. Sep 01, 2015

Pubmed Data : J Ethnopharmacol. 2015 Sep 2. Epub 2015 Sep 2. PMID: 26342520
Article Published Date : Sep 01, 2015
Study Type : Animal Study
Additional Links
Substances : Turmeric
Diseases : Asthma, Atopic Dermatitis, Food Allergies, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Allergic Agents, Immunomodulatory
[+]

Vitamin D deficiency during pregnancy affects the function of Th1/Th2 cells and methylation of IFN-γ gene in offspring.Jun 27, 2019

Pubmed Data : Immunol Lett. 2019 Jun 28. Epub 2019 Jun 28. PMID: 31260744
Article Published Date : Jun 27, 2019
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Vitamin D Deficiency
Pharmacological Actions : Immunomodulatory
[+]

Xanthohumol promoted Th1/Th2 balance towards Th1 polarization.Dec 31, 2017

Pubmed Data : Oncol Rep. 2018 Jan ;39(1):280-288. Epub 2017 Nov 13. PMID: 29138867
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Xanthohumol
Diseases : Breast Cancer, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Zerumbone exhibits an antiallergic effect via modulation of Th1/Th2 cytokines in an asthmatic mouse model.Jan 31, 2015

Pubmed Data : Int Immunopharmacol. 2015 Feb ;24(2):383-91. Epub 2015 Jan 5. PMID: 25573403
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : Zerumbone
Diseases : Allergies, Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Allergic Agents, Immunomodulatory, Interleukin-10 downregulation, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

The immune-enhancing potential of peptide fractions from fermented Spirulina platensis by mixed probiotics.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Food Biochem. 2020 Jul ;44(7):e13245. Epub 2020 May 27. PMID: 32462664
Article Published Date : Jun 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Probiotics, Spirulina
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Adjuvants in vaccines may trigger innate cells response by toll-like receptors, thus eliciting a possible non-IgE mediated allergy phenomenon or causing B-cell activation and autoimmunity.Aug 01, 2011

Pubmed Data : Hum Vaccin. 2011 Aug 1 ;7(8). Epub 2011 Aug 1. PMID: 21785282
Article Published Date : Aug 01, 2011
Study Type : Review
Additional Links
Diseases : Autoimmune Diseases, Hypersensitivity, Immune Disorders: B-Cell Over-Activity, Immune Dysregulation: TH1/TH2 imbalance, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Adjuvant
[+]

Bisphenol A exposure may contribute to autoimmune and inflammatory conditions.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(8):e0161122. Epub 2016 Aug 10. PMID: 27509021
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Diseases : Autoimmune Diseases, Immune Dysregulation: TH1/TH2 imbalance, Inflammation
Problem Substances : Bisphenol A
[+]

Cannabinoids have the potential to regulate the activation and balance of human Th1/Th2 cells by a CB2 receptor-dependent pathway.Nov 30, 2002

Pubmed Data : J Neuroimmunol. 2002 Dec ;133(1-2):124-31. PMID: 12446015
Article Published Date : Nov 30, 2002
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
Additional Keywords : Cannabinoid Receptors
[+]

Cordyceps has a harmonizing (yin-yang) effect on TH1/TH2 balance and activity. Jun 01, 2009

Pubmed Data : J Leukoc Biol. 2009 Jun;85(6):987-95. Epub 2009 Mar 4. PMID: 19261928
Article Published Date : Jun 01, 2009
Study Type : Commentary
Additional Links
Substances : Cordyceps sinensis
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Additional Keywords : Ying-Yang Effect
[+]

Crocetin can have therapeutic value for treating predominant diseases of Th2 or Th17 cells.Feb 05, 2023

Pubmed Data : Biofactors. 2023 Feb 6. Epub 2023 Feb 6. PMID: 36747328
Article Published Date : Feb 05, 2023
Study Type : In Vitro Study
Additional Links
Substances : Crocetin
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory, Nitric Oxide Inhibitor
[+]

EPA may have a positive immunomodulatory role through the induction of regulatory T cells in autoimmune conditions.May 01, 2004

Pubmed Data : J Neurosci Res. 2004 May 1;76(3):397-405. PMID: 21182821
Article Published Date : May 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : EPA (Eicosapentaenoic Acid)
Diseases : Autoimmune Diseases, Immune Dysregulation: TH1/TH2 imbalance, Immune Function: TH2 dominance
Pharmacological Actions : Immunomodulatory
[+]

Ginsenoside-Ro showed immunomodulatory effects by regulating the production and expression of Th1/Th2 cytokines in murine splenocytes.Mar 31, 2005

Pubmed Data : Yao Xue Xue Bao. 2005 Apr ;40(4):332-6. PMID: 16011261
Article Published Date : Mar 31, 2005
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

Helenalin, a compound found within Arnica, may have a role as an immunosuppressive compound suited for the treatment of deregulated and unwanted T cell-mediated immune responses.Sep 01, 2009

Pubmed Data : Mol Immunol. 2009 Sep;46(15):2892-901. Epub 2009 Aug 5. PMID: 19656571
Article Published Date : Sep 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Arnica, Helenalin
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Immunosuppressive Agents, NF-kappaB Inhibitor, Proteasome Inhibitors, Tumor Suppressor Protein p53 Upregulation
[+]

Maitake D-Fraction establishes Th-1 dominance which induces cellular immunity in the population that was Th-2 dominant due to carcinoma.Apr 01, 2002

Pubmed Data : Biol Pharm Bull. 2002 Apr;25(4):536-40. PMID: 11995941
Article Published Date : Apr 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Tumor, Interferon Inducers, Interleukin-12 upregulation, Interleukin-18 upregulation
[+]

Papaya leaf extract may exhibit anti-tumor properties by shifting the immune system towards the Th1 pole.Feb 17, 2010

Pubmed Data : J Ethnopharmacol. 2010 Feb 17;127(3):760-7. Epub 2009 Dec 2. PMID: 19961915
Article Published Date : Feb 17, 2010
Study Type : In Vitro Study
Additional Links
Substances : Papaya
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Low Disorders: Low TH1, Tumors
Pharmacological Actions : Antiproliferative , Apoptotic, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Safranal may have therapeutic effects in inflammatory diseases associated with Th1/Th2 imbalance.Nov 30, 2016

Pubmed Data : Iran J Immunol. 2016 Dec ;13(4):263-273. PMID: 27999238
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Safranal
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory, Interferon-gamma (IFN-gamma) inducer, Interleukin-4 upregulation
[+]

These results showed an immunomodulatory effect for the extract of P. oleracea.May 31, 2019

Pubmed Data : Altern Ther Health Med. 2019 Jun 1. Epub 2019 Jun 1. PMID: 31221948
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Purslane
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory

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