Insulin: Elevated

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57 Substances Researched for Insulin: Elevated
NameACCKFocus
Fiber432Locked
Berries: All120Locked
Chocolate120Locked
Cocoa120Locked
Flavan-3-ols120Locked
Acetic Acid110Locked
Almond110Locked
Alpha-Lipoic Acid110Locked
Beta-glucan110Locked
Black Currant110Locked
Bran 110Locked
Broccoli Sprouts110Locked
Cayenne110Locked
Chili pepper110Locked
Chinese Herbal Formula: Tiangui Fang110Locked
Lingonberry110Locked
Monounsaturated fatty acids110Locked
Oleic acid110Locked
Omega-3 Fatty Acids110Locked
Rye110Locked
Sulforaphane110Locked
Vinegar110Locked
Walnut110Locked
Wheat Bran110Locked
Nigella sativa (aka Black Seed)36Locked
Coffee24Locked
Polyphenols24Locked
Turmeric24Locked
Anthocyanins12Locked
Blue Honeysuckle12Locked
Chinese Skullcap 12Locked
Curcumin12Locked
Garlic12Locked
Ginger12Locked
Grape12Locked
Grape Seed Extract12Locked
Krill12Locked
Lactobacillus casei12Locked
Litchi12Locked
Loquat12Locked
Magnesium12Locked
Maitake Mushroom12Locked
Mangiferin12Locked
Prickly Pear Cactus12Locked
Proanthocyanidins12Locked
Psyllium12Locked
Theanine12Locked
Ursolic Acid12Locked
Vanadyl Sulfate12Locked
Yerba Mate12Locked
Apigenin11Locked
Fisetin11Locked
Flavonoids11Locked
Kaempferol11Locked
Luteolin11Locked
Quercetin11Locked
Raisins11Locked
21 Problem Substances Researched for Insulin: Elevated
NameACCKFocus
Insulin 738Locked
Fructose920Locked
Rye120Locked
Wheat120Locked
Sucrose110Locked
Sugar Sweetened Beverages110Locked
Acesulfame potassium 35Locked
Gluten24Locked
Monosodium Glutamate (MSG)24Locked
Cow Milk23Locked
Aspartame12Locked
Ethanol12Locked
Gliadin12Locked
Gluten exorphins12Locked
Metformin 12Locked
Trans Fatty Acids12Locked
Artificial Sweeteners11Locked
Concanavalin A11Locked
Saccharin11Locked
Sodium Cyclamate11Locked
Wheat Germ Agglutinin (WGA)11Locked
6 Therapeutic Actions Researched for Insulin: Elevated
NameACCKFocus
Fasting/Caloric Restriction220Locked
Blood Donation110Locked
Dietary Modification: Caloric Restriction 110Locked
Phlebotomy110Locked
Dietary Modification: Low Carbohydrate/Ketogenic13Locked
Exercise12Locked
1 Problematic Actions Researched for Insulin: Elevated
NameACCKFocus
Western Diet12Locked

View the Evidence:
73 Abstracts with Insulin: Elevated Research

[+]

Meta-analysis: Chocolate, cocoa and flavan-3-ols improve insulin resistance, reduces serum insulin levels, and parameters associated with cardiovascular disease risk. Feb 01, 2012

Pubmed Data : Am J Clin Nutr. 2012 Feb 1. Epub 2012 Feb 1. PMID: 22301923
Article Published Date : Feb 01, 2012
Study Type : Meta Analysis
Additional Links
Substances : Chocolate, Cocoa, Flavan-3-ols
Diseases : Cardiovascular Diseases, Hypertension, Insulin: Elevated, Insulin Resistance
Pharmacological Actions : Hypotensive
[+]

After 4 weeks consuming broccoli sprouts powder it resulted in a significant decrease in serum insulin concentration in patients. Oct 31, 2012

Pubmed Data : Int J Food Sci Nutr. 2012 Nov ;63(7):767-71. Epub 2012 Apr 26. PMID: 22537070
Article Published Date : Oct 31, 2012
Study Type : Human Study
Additional Links
Substances : Broccoli Sprouts, Sulforaphane
Diseases : Diabetes Mellitus: Type 2, Hyperinsulinism, Insulin Resistance
Pharmacological Actions : Antioxidants, Insulin Down-Regulation
[+]

Almonds reduce insulin secretion and insulin resistance in nondiabetic hyperlipidemic subjects. Jul 01, 2008

Pubmed Data : Metabolism. 2008 Jul;57(7):882-7. PMID: 18555827
Article Published Date : Jul 01, 2008
Study Type : Human Study
Additional Links
Substances : Almond
Diseases : Hyperinsulinism, Hyperlipidemia
[+]

Berries reduce postprandial insulin responses to wheat and rye breads in healthy women.Mar 31, 2013

Pubmed Data : J Nutr. 2013 Apr ;143(4):430-6. Epub 2013 Jan 30. PMID: 23365108
Article Published Date : Mar 31, 2013
Study Type : Human Study
Additional Links
Substances : Berries: All
Diseases : Hyperinsulinism, Insulin: Elevated, Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Rye, Wheat
Adverse Pharmacological Actions : Insulinotropic
[+]

Caloric restriction ameliorates defective insulin binding to receptors in obese men. Jan 01, 1975

Pubmed Data : J Clin Invest. 1975 Jan;55(1):166-74. PMID: 1109176
Article Published Date : Jan 01, 1975
Study Type : Human Study
Additional Links
Diseases : Hyperinsulinism, Insulin Resistance
Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction
[+]

Clamping cortisol and testosterone mitigates the development of insulin resistance during sleep restriction in men.Aug 17, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Endocrinol Metab. 2021 Aug 18 ;106(9):e3436-e3448. PMID: 34043794
Article Published Date : Aug 17, 2021
Study Type : Human Study
Additional Links
Diseases : Hyperinsulinism, Insomnia, Insulin Resistance, Sleep Disorders
[+]

Controlled-release alpha lipoic acid has a therapeutic effect in lean, nondiabetic patients with polycystic ovary syndrome.Mar 01, 2010

Pubmed Data : J Diabetes Sci Technol. 2010 Mar;4(2):359-64. Epub 2010 Mar 1. PMID: 20307398
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Hyperinsulinism, Insulin Resistance, Oxidative Stress, Polycystic Ovary Syndrome
[+]

Four grams of high molecular weight oat β-glucan lowers appetite but not ad libitum eating and beneficially modulates postprandial glycemia.Jan 01, 2018

Pubmed Data : Appetite. 2018 09 1 ;128:197-204. Epub 2018 Jun 18. PMID: 29920323
Article Published Date : Jan 01, 2018
Study Type : Human Study
Additional Links
Substances : Beta-glucan
Diseases : Hyperglycemia, Hyperinsulinism
Pharmacological Actions : Hypoglycemic Agents
Problem Substances : Insulin
[+]

Higher insulin concentrations, as well as the presence of insulin resistance, appear to be associated with an elevated risk of lung cancer development.Jul 10, 2017

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2017 Jul 11. Epub 2017 Jul 11. PMID: 28698186
Article Published Date : Jul 10, 2017
Study Type : Human Study
Additional Links
Diseases : Insulin: Elevated, Insulin Resistance, Lung Cancer
Additional Keywords : Risk Factors
[+]

In patients with METS, phlebotomy, with consecutive reduction of body iron stores, lowered BP and resulted in improvements in markers of cardiovascular risk and glycemic control.Dec 31, 2011

Pubmed Data : BMC Med. 2012 ;10:54. Epub 2012 May 30. PMID: 22647517
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Diseases : Hyperinsulinism, Hypertension, Insulin Resistance, Metabolic Syndrome X
Therapeutic Actions : Blood Donation, Phlebotomy
[+]

Insulinemic and inflammatory dietary patterns and risk of prostate cancer. Jan 05, 2021

Pubmed Data : Eur Urol. 2021 Jan 6. Epub 2021 Jan 6. PMID: 33422354
Article Published Date : Jan 05, 2021
Study Type : Human Study
Additional Links
Diseases : Hyperinsulinism, Inflammation, Prostate Cancer
Additional Keywords : Inflammatory Diet, Risk Factors
[+]

Orange pomace fiber lowers postprandial glycemic and insulinemic responses in men with increased cardiometabolic risk.Jan 01, 2016

Pubmed Data : J Nutr. 2016 06 ;146(6):1197-203. Epub 2016 May 11. PMID: 27170728
Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Cardiovascular Diseases, Hyperglycemia, Hyperinsulinism
Pharmacological Actions : Hypoglycemic Agents
Problem Substances : Insulin
[+]

Postmeal fluctuations in blood glucose and insulin induced by sucrose are alleviated when sucrose is consumed with blackcurrants or lingonberries. Aug 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2012 Sep ;96(3):527-33. Epub 2012 Aug 1. PMID: 22854401
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Substances : Black Currant, Lingonberry
Diseases : Hyperinsulinism
Pharmacological Actions : Glucose Uptake Optimization
Additional Keywords : Metabolic Regulation
Problem Substances : Insulin , Sucrose
[+]

Pre-exercise carbohydrate ingestion after a 4-hour fast is sufficient to induce a transient hypoglycemia.May 01, 1999

Pubmed Data : Int J Sports Med. 1999 May;20(4):227-31. PMID: 10376478
Article Published Date : May 01, 1999
Study Type : Human Study
Additional Links
Diseases : Hyperinsulinism, Hypoglycemia
[+]

Regular consumption of chili may attenuate postprandial hyperinsulinemia.Jul 01, 2006

Pubmed Data : Am J Clin Nutr. 2006 Jul;84(1):63-9. PMID: 16825682
Article Published Date : Jul 01, 2006
Study Type : Human Study
Additional Links
Substances : Cayenne, Chili pepper
Diseases : Hyperinsulinism
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Substituting saturated fats with monounsaturated fats within high-fat diets attenuates hyperinsulinemia and pancreatic islet dysfunction.Mar 03, 2020

Pubmed Data : Br J Nutr. 2020 Mar 3:1-22. Epub 2020 Mar 3. PMID: 32122411
Article Published Date : Mar 03, 2020
Study Type : Human Study
Additional Links
Substances : Monounsaturated fatty acids, Oleic acid
Diseases : Hyperinsulinism, Pancreatic Diseases
Pharmacological Actions : Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK, Anti-Inflammatory Agents
[+]

The Chinese herbal formula "tiangui fang" may have value in the treatment of hyperandrogenism and hyperinsulinism in polycystic ovary syndrome.Aug 01, 2000

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Aug ;20(8):589-92. PMID: 11789189
Article Published Date : Aug 01, 2000
Study Type : Human Study
Additional Links
Substances : Chinese Herbal Formula: Tiangui Fang
Diseases : Adrenal Hyperandrogenism, Hyperinsulinism, Polycystic Ovary Syndrome
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Drug: Metformin
[+]

The consumption of sugar-sweetened beverages was associated with higher concentrations of insulin and leptin and a higher HOMA-IR.Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr. 2014 Jul ;144(7):1099-105. Epub 2014 May 14. PMID: 24828025
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Diseases : Hyperinsulinism, Insulin Resistance
Additional Keywords : Risk Factors
Problem Substances : Sugar Sweetened Beverages
[+]

Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects.Sep 01, 2005

Pubmed Data : Eur J Clin Nutr. 2005 Sep ;59(9):983-8. PMID: 16015276
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : Acetic Acid, Vinegar
Diseases : Hyperinsulinism
Pharmacological Actions : Hypoglycemic Agents
[+]

Walnuts may improve metabolic parameters in type II diabetes.Aug 01, 2009

Pubmed Data : Eur J Clin Nutr. 2009 Aug ;63(8):1008-15. Epub 2009 Apr 8. PMID: 19352378
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids, Walnut
Diseases : Diabetes Mellitus: Type 2, Hyperinsulinism, Metabolic Syndrome X
[+]

Wheat fiber supplementation increases GLP-1 secretion and improves colonic fermentation by-products in hyperinsulinemic patients. Jan 01, 2010

Pubmed Data : Br J Nutr. 2010 Jan;103(1):82-90. Epub 2009 Aug 7. PMID: 19664300
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Fiber, Wheat Bran
Diseases : Hyperinsulinism, Insulin Resistance
Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation
[+]

Whole grain and bran from rye resulted in significantly lower plasma PSA in patients with prostate cancer.Dec 01, 2010

Pubmed Data : J Nutr. 2010 Dec;140(12):2180-6. Epub 2010 Oct 27. PMID: 20980650
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Substances : Bran , Fiber, Rye
Diseases : Hyperinsulinism, Prostate Cancer
[+]

The ketogenic diet could represent an effective treatment to support brain function in selected cases of congenital hyperinsulinism.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Orphanet J Rare Dis. 2015 ;10(1):120. Epub 2015 Sep 24. PMID: 26399329
Article Published Date : Dec 31, 2014
Study Type : Human: Case Report
Additional Links
Diseases : Congenital Disorders, Hyperinsulinism, Seizures
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Additional Keywords : Significant Treatment Outcome
[+]

"Brain insulin impairs amyloid-beta(1-40) clearance from the brain."Oct 26, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurosci. 2004 Oct 27 ;24(43):9632-7. PMID: 15509750
Article Published Date : Oct 26, 2004
Study Type : Animal Study
Additional Links
Diseases : Aging: Brain , Hyperinsulinism
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Insulin
[+]

A combination of black seeds and turmeric at low doses showed enhanced efficacy in preventing metabolic syndrome in fructose fed rats.Jan 31, 2015

Pubmed Data : J Cardiovasc Pharmacol. 2015 Feb ;65(2):176-83. PMID: 25384193
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed), Turmeric
Diseases : Dyslipidemias, Endothelial Dysfunction, Fructose-Induced Toxicity , Hyperglycemia, Hyperinsulinism, Hypertension, Metabolic Diseases
Pharmacological Actions : Anticholesteremic Agents, Antihypertensive Agents, Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Natural Substance Synergy, Risk Reduction
[+]

A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats.Jan 01, 2012

Pubmed Data : PLoS One. 2012 ;7(6):e38797. Epub 2012 Jun 7. PMID: 22685607
Article Published Date : Jan 01, 2012
Study Type : Animal Study
Additional Links
Substances : Krill
Diseases : Fatty Liver, Insulin: Elevated, Triglycerides: Elevated
Pharmacological Actions : Hepatoprotective
[+]

A water extract of maitake mushroom reduces circulating glucose/insulin concentrations in insulin-resistant mice. Jan 01, 2002

Pubmed Data : Diabetes Obes Metab. 2002 Jan;4(1):43-8. PMID: 11874441
Article Published Date : Jan 01, 2002
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Hyperinsulinism, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents
[+]

Acesulfame K acts directly on the pancreatic islets and potentiates glucose-induced insulin release.Jul 01, 1987

Pubmed Data : Horm Metab Res. 1987 Jul;19(7):285-9. PMID: 2887503
Article Published Date : Jul 01, 1987
Study Type : Animal Study
Additional Links
Diseases : Hyperinsulinism
Problem Substances : Acesulfame potassium
[+]

Acesulfame stimulates insulin secretion. Jun 01, 1987

Pubmed Data : Horm Metab Res. 1987 Jun;19(6):233-8. PMID: 2887500
Article Published Date : Jun 01, 1987
Study Type : Animal Study
Additional Links
Diseases : Hyperinsulinism
Problem Substances : Acesulfame potassium
[+]

An anthocyanin-rich Kamchatka honeysuckle berry extract supplemented to an unbalanced diet is able to ameliorate disturbances in lipid/glucose metabolism that are risk factors for CVD and diabetes.May 31, 2013

Pubmed Data : Nutrition. 2013 Jun ;29(6):898-902. Epub 2013 Feb 16. PMID: 23422536
Article Published Date : May 31, 2013
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Blue Honeysuckle
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2: Prevention, Fructose-Induced Toxicity , Hyperinsulinism, Hyperlipidemia, Insulin Resistance, Triglycerides: Elevated
Pharmacological Actions : Alpha-glucosidase inhibitor , Cardioprotective, Hypolipidemic
Additional Keywords : Metabolism Of Polyphenols, Plant Extracts, Risk Reduction
[+]

Aspartame exposure may promote hyperglycemia and insulin intolerance. MSG may interact with aspartame to further impair glucose homeostasis.Jun 14, 2012

Pubmed Data : Nutr Metab (Lond). 2012 Jun 14 ;9(1):58. Epub 2012 Jun 14. PMID: 22697049
Article Published Date : Jun 14, 2012
Study Type : Animal Study
Additional Links
Diseases : Hyperglycemia, Insulin: Elevated, Insulin Resistance
Problem Substances : Aspartame, Monosodium Glutamate (MSG)
Adverse Pharmacological Actions : Diabetogenic, Endocrine Disruptor: Insulin Resistance
[+]

Baicalin suppresses body weight gain, visceral fat mass, serum cholesterol, free fatty acid and insulin concentrations caused by a high-fat diet. Nov 01, 2009

Pubmed Data : Acta Pharmacol Sin. 2009 Nov;30(11):1505-12. PMID: 19890358
Article Published Date : Nov 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Abdominal Obesity (Midsection Fat), Fatty Liver, Hyperinsulinism, Obesity
[+]

Coffee polyphenols modulate whole-body substrate oxidation and suppress postprandial hyperglycaemia, hyperinsulinaemia and hyperlipidaemia.Jun 01, 2012

Pubmed Data : Br J Nutr. 2012 Jun ;107(12):1757-65. Epub 2011 Sep 29. PMID: 22017960
Article Published Date : Jun 01, 2012
Study Type : Animal Study
Additional Links
Substances : Coffee, Polyphenols
Diseases : Hyperglycemia, Hyperinsulinism, Hyperlipidemia
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Coffee polyphenols modulate whole-body substrate oxidation and suppress postprandial hyperglycaemia, hyperinsulinaemia and hyperlipidaemia.Jun 01, 2012

Pubmed Data : Br J Nutr. 2012 Jun ;107(12):1757-65. Epub 2011 Sep 29. PMID: 22017960
Article Published Date : Jun 01, 2012
Study Type : Animal Study
Additional Links
Substances : Coffee, Polyphenols
Diseases : Hyperglycemia, Hyperinsulinism, Hyperlipidemia
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Curcuma oil treatment significantly attenuated diabetic dyslipidaemia, insulin resistance and associated deleterious effects in HFr fed hamsters and rats. May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Med Res. 2015 Jun ;141(6):823-32. PMID: 26205026
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Turmeric
Diseases : Endothelial Dysfunction, High Fructose Diet, Hyperglycemia, Hyperinsulinism, Hyperlipidemia, Oxidative Stress
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Natural Substances Versus Drugs
[+]

Curcumin reduces the adverse effects of hyperinsulinemia associated with type 2 diabetes by attenuating the effects of insulin on hepatic stellate cell activation and reducing oxidative stress. Jun 01, 2010

Pubmed Data : Clin Breast Cancer. 2010 Jun;10(3):224-9. PMID: 19841616
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Fatty Liver, Hepatic Steatosis, Hyperinsulinism, Liver Fibrosis
[+]

Ethanol acutely stimulates islet blood flow, amplifies insulin secretion, and induces hypoglycemia via nitric oxide and vagally mediated mechanisms.Jan 01, 2008

Pubmed Data : Endocrinology. 2008 Jan;149(1):232-6. Epub 2007 Oct 4. PMID: 17916634
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Hyperinsulinism, Hypoglycemia
Problem Substances : Ethanol
[+]

Exercise improves fructose-induced insulin resistance, hyperinsulinemia and hypertension.Aug 01, 1988

Pubmed Data : Hypertension. 1988 Aug;12(2):129-32. PMID: 3410522
Article Published Date : Aug 01, 1988
Study Type : Animal Study
Additional Links
Diseases : Fructose-Induced Toxicity , Hyperinsulinism, Hypertension, Insulin Resistance
Therapeutic Actions : Exercise
Problem Substances : Fructose
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance, Hypertensive
[+]

Fiber attenuates weight gain, enhances insulin sensitivity, and modulates leptin and GLP-1 secretion and gastric ghrelin gene expressionDec 01, 2007

Pubmed Data : Metabolism. 2007 Dec;56(12):1635-42. PMID: 17998014
Article Published Date : Dec 01, 2007
Study Type : Animal Study
Additional Links
Substances : Fiber, Psyllium
Diseases : Hyperglycemia, Hyperinsulinism, Leptin: Elevated Levels, Overweight
Pharmacological Actions : Ghrelin Down-Regulation, Glucagon Like peptide 1 (GLP-1) Up-regulation, Hypoglycemic Agents, Insulin Down-Regulation
[+]

Fructose is used in an experimental model to induce metabolic syndrome. May 01, 2011

Pubmed Data : Acta Med Iran. 2011 May;49(5):277-83. PMID: 21713743
Article Published Date : May 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Cholesterol: LDL/HDL ratio, High Cholesterol: very low density lipoprotein (VLDL), Insulin: Elevated, Insulin Resistance, Metabolic Syndrome X, Triglycerides: Elevated
Problem Substances : Fructose
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance
[+]

Fructose is used to induce hypertension in the animal model. Aug 01, 1989

Pubmed Data : Hypertension. 1989 Aug;14(2):117-20. PMID: 2569446
Article Published Date : Aug 01, 1989
Study Type : Animal Study
Additional Links
Diseases : Fructose-Induced Toxicity , Hypertension, Insulin: Elevated, Insulin Resistance
Problem Substances : Fructose
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance, Hypertensive
[+]

Fructose is used to induced hyperinsulinemia, hypertriglyceridemia and hypertension in an animal moodel.Jun 01, 1989

Pubmed Data : Am J Hypertens. 1989 Jun;2(6 Pt 1):424-7. PMID: 2527043
Article Published Date : Jun 01, 1989
Study Type : Animal Study
Additional Links
Diseases : Fructose-Induced Toxicity , Hyperinsulinism, Hypertension, Triglycerides: Elevated
Problem Substances : Fructose
Adverse Pharmacological Actions : Dyslipidemic, Hypertensive
[+]

Fructose-fed animals develop hyperglycemia, hyperinsulinemia, hypertriglyceridemia and insulin resistance.Jun 24, 2011

Pubmed Data : Chem Biol Interact. 2011 Jun 24. Epub 2011 Jun 24. PMID: 21708140
Article Published Date : Jun 24, 2011
Study Type : Animal Study
Additional Links
Diseases : Hyperglycemia, Insulin: Elevated, Insulin Resistance, Triglycerides: Elevated
Problem Substances : Fructose
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance
[+]

Fructose-induced hypertriglyceridemia is associated with significant hyperinsulinemia.Apr 01, 1980

Pubmed Data : Metabolism. 1980 Apr;29(4):303-5. PMID: 6990170
Article Published Date : Apr 01, 1980
Study Type : Animal Study
Additional Links
Diseases : Hyperinsulinism, Insulin: Elevated, Triglycerides: Elevated
Additional Keywords : Diseases that are Linked
Problem Substances : Fructose
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance
[+]

Garlic improves insulin sensitivity and associated metabolic syndromes in fructose fed rats.Jan 01, 2011

Pubmed Data : Nutr Metab (Lond). 2011 ;8:53. Epub 2011 Jul 27. PMID: 21794123
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Fructose-Induced Toxicity , Hyperuricemia, Insulin: Elevated, Insulin Resistance, Metabolic Syndrome X, Triglycerides: Elevated
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Fructose
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance
[+]

Ginger has a beneficial effect on fructose induced hyperlipidemia an dhyperinsulinemia in rats. Dec 01, 2005

Pubmed Data : Indian J Exp Biol. 2005 Dec;43(12):1161-4. PMID: 16359128
Article Published Date : Dec 01, 2005
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Fructose-Induced Toxicity , Hyperinsulinism, Hyperlipidemia, Metabolic Syndrome X
Additional Keywords : Plant Extracts
[+]

Gluten exorphin modulate pancreatic endocrine function by stimulating insulin release.Jan 01, 1995

Pubmed Data : Life Sci. 1995;57(7):729-34. PMID: 7637543
Article Published Date : Jan 01, 1995
Study Type : Animal Study
Additional Links
Diseases : Insulin: Elevated, Insulin Disorders
Problem Substances : Gluten exorphins
Adverse Pharmacological Actions : Endocrine Disruptor: Pancreas
[+]

Gluten exorphins have an effect on plasma insulin and glucagon levels in dogs.Apr 01, 1981

Pubmed Data : Diabetes. 1981 Apr ;30(4):362-4. PMID: 7009280
Article Published Date : Apr 01, 1981
Study Type : Animal Study
Additional Links
Diseases : Glucagon: Excess Secretion, Insulin: Elevated
Problem Substances : Gluten
Adverse Pharmacological Actions : Endocrine Disruptor, Endocrine Disruptor: Insulin Resistance
[+]

Gluten-free diet prevents diabetes in NOD mice.Aug 31, 1999

Pubmed Data : Diabetes Metab Res Rev. 1999 Sep-Oct;15(5):323-7. PMID: 10585617
Article Published Date : Aug 31, 1999
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 1: Prevention, Hyperinsulinism
Problem Substances : Gliadin, Gluten
Adverse Pharmacological Actions : Diabetogenic, Immunotoxic
[+]

Grape seed proanthocyanidins is superior to metformin to promote insulin signaling in rats fed high calorie diet.Sep 11, 2013

Pubmed Data : J Cell Commun Signal. 2013 Sep 12. Epub 2013 Sep 12. PMID: 24026800
Article Published Date : Sep 11, 2013
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract, Proanthocyanidins
Diseases : Blood Sugar Problems, Diabetes Mellitus: Type 2, Hyperglycemia, Hyperinsulinism
Additional Keywords : Superiority of Natural Substances versus Drugs
Problem Substances : Metformin
[+]

Hypoglycemic effect of Opuntia ficus-indica var. saboten is due to enhanced peripheral glucose uptake.Dec 08, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Dec 9 ;8(12). Epub 2016 Dec 9. PMID: 27941667
Article Published Date : Dec 08, 2016
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Hyperglycemia, Hyperinsulinism, Insulin Resistance
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Insulin may contribute to myopia. Jan 01, 2009

Pubmed Data : Invest Ophthalmol Vis Sci. 2009 Jan;50(1):13-23. Epub 2008 Jul 3. PMID: 18599564
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Hyperinsulinism, Myopia
Additional Keywords : Diseases that are Linked
Problem Substances : Insulin
Adverse Pharmacological Actions : Myopiagenic
[+]

L-theanine suppresses food intake in rats, and may lower insulin levels.May 01, 2008

Pubmed Data : Biosci Biotechnol Biochem. 2008 May;72(5):1352-5. Epub 2008 May 7. PMID: 18460793
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Appetite Disorders, Hyperinsulinism
[+]

Lactobacilluscasei Zhang administration exert both preventive and ameliorative effect on oral glucose tolerance.Jan 31, 2014

Pubmed Data : Eur J Nutr. 2014 Feb ;53(1):221-32. PMID: 23797890
Article Published Date : Jan 31, 2014
Study Type : Animal Study
Additional Links
Substances : Lactobacillus casei
Diseases : Hyperinsulinism
Pharmacological Actions : Malondialdehyde Down-regulation
Additional Keywords : hyperinsulinism, Lactobacillus casei, Malondialdehyde Down-regulation
Problem Substances : Fructose
[+]

Litchi seeds have a wide range of benefits in insulin resistant rats with type 2 diabetes. Jun 01, 2004

Pubmed Data : Zhong Yao Cai. 2004 Jun;27(6):435-8. PMID: 15524300
Article Published Date : Jun 01, 2004
Study Type : Animal Study
Additional Links
Substances : Litchi
Diseases : Diabetes Mellitus: Type 2, Hyperinsulinism, Hyperleptinemia, Insulin Resistance
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Loquat improves hyperlipidemia and reverses insulin resistance in high-fat-fed mice.Dec 01, 2010

Pubmed Data : Phytother Res. 2010 Dec;24(12):1769-80. PMID: 20564460
Article Published Date : Dec 01, 2010
Study Type : Animal Study
Additional Links
Substances : Loquat
Diseases : Hyperinsulinism, Hyperlipidemia, Insulin Resistance
Additional Keywords : Plant Extracts
[+]

Magnesium sulfate attenuates increased blood-brain barrier permeability during insulin-induced hypoglycemia in rats.Sep 01, 2001

Pubmed Data : Can J Physiol Pharmacol. 2001 Sep;79(9):793-8. PMID: 11599780
Article Published Date : Sep 01, 2001
Study Type : Animal Study
Additional Links
Substances : Magnesium
Diseases : Blood-Brain-Barrier Disorders, Hyperinsulinism, Hypoglycemia
[+]

Mangiferin exhibits anti-diabetic properties.Mar 01, 2001

Pubmed Data : Phytomedicine. 2001 Mar;8(2):85-7. PMID: 11315760
Article Published Date : Mar 01, 2001
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Diabetes Mellitus: Type 2, Hyperglycemia, Hyperinsulinism, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts, Xanthones
[+]

Monosodium glutamate induces fatty liver, insulin and triglyceride elevations, increased weight gain and adverse liver changes.Aug 01, 2009

Pubmed Data : J Lipid Res. 2009 Aug;50(8):1521-37. Epub 2008 Nov 11. PMID: 19001666
Article Published Date : Aug 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Fatty Liver, Hyperinsulinism, Liver Damage, Triglycerides: Elevated, Weight Problems
Problem Substances : Insulin , Monosodium Glutamate (MSG), Trans Fatty Acids
[+]

Nigella sativa (black cumin) protects against chronic antiretroviral therapy-associated insulin resistance in HIV-1 infected rats. Apr 01, 2009

Pubmed Data : Can J Physiol Pharmacol. 2009 Apr;87(4):300-9. PMID: 19370083
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : HIV Drug-Induced Toxicity , Hyperinsulinism
Pharmacological Actions : Antioxidants
Additional Keywords : Drug Side Effect Attenuation
[+]

Nigella sativa oil and chromium picolinate monotherapy can reduce fructose-induced insulin resistance.Oct 03, 2017

Pubmed Data : Biol Trace Elem Res. 2017 Oct 4. Epub 2017 Oct 4. PMID: 28975521
Article Published Date : Oct 03, 2017
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : High Fructose Diet, Hyperinsulinism
Pharmacological Actions : Insulin Sensitizers
[+]

Protective effect of vanillic acid against hyperinsulinemia, hyperglycemia and hyperlipidemia.Dec 01, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 Dec 2 ;7(12):9946-59. Epub 2015 Dec 2. PMID: 26633482
Article Published Date : Dec 01, 2015
Study Type : Animal Study
Additional Links
Substances : Vanillic Acid
Diseases : Hyperinsulinism, Hyperlipidemia, Inflammation, Insulin Resistance
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Insulin Sensitizers, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Red grape berry-cultured cells reduce blood pressure in rats with metabolic-like syndrome.Mar 31, 2014

Pubmed Data : Eur J Nutr. 2014 Apr ;53(3):973-80. Epub 2013 Oct 26. PMID: 24158651
Article Published Date : Mar 31, 2014
Study Type : Animal Study
Additional Links
Substances : Grape
Diseases : Hyperinsulinism, Hypertension
Pharmacological Actions : Antihypertensive Agents
Additional Keywords : Plant Extracts
[+]

Ursolic acid demonstrated its potential therapeutic utility to improve IR, hyperinsulinemia, and inflammation observed in obesity and diabetes.Nov 19, 2019

Pubmed Data : J Med Food. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31747348
Article Published Date : Nov 19, 2019
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : Hyperinsulinism, Insulin Resistance, Obesity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Vanadyl sulfate ameliorates insulin resistance and restores plasma dehydroepiandrosterone-sulfate levels in fructose-fed, insulin-resistant rats.Aug 01, 2004

Pubmed Data : Clin Biochem. 2004 Aug;37(8):694-7. PMID: 15302613
Article Published Date : Aug 01, 2004
Study Type : Animal Study
Additional Links
Substances : Vanadyl Sulfate
Diseases : DHEA: Low, Fructose-Induced Toxicity , Hyperinsulinism, Insulin Resistance
Problem Substances : Fructose
[+]

Yerba mate has a protective effect against a high-fat diet induced obesity in rats through significantly lowering body weight, visceral fat, blood and liver lipids, glucose, insulin and leptin levels. Aug 15, 2008

Pubmed Data : Arch Biochem Biophys. 2008 Aug 15;476(2):178-85. Epub 2008 Feb 26. PMID: 18314006
Article Published Date : Aug 15, 2008
Study Type : Animal Study
Additional Links
Substances : Yerba Mate
Diseases : Abdominal Obesity (Midsection Fat), Hyperinsulinism, Leptin: Elevated Levels, Obesity
[+]

"Milk--the promoter of chronic Western diseases." Jun 01, 2009

Pubmed Data : Med Hypotheses. 2009 Jun ;72(6):631-9. Epub 2009 Feb 15. PMID: 19232475
Article Published Date : Jun 01, 2009
Study Type : Commentary
Additional Links
Diseases : Acne, Allergy: Cow's Milk , Atherosclerosis, Casein Intolerance, Diabetes Mellitus: Type 1, Hyperinsulinism, Insulin-like Growth Factor (IGF): Elevated, Neurodegenerative Diseases, Obesity
Problem Substances : Cow Milk
[+]

"Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization."Jan 01, 2011

Pubmed Data : Nutr Metab (Lond). 2011 ;8:41. Epub 2011 Jun 24. PMID: 21699736
Article Published Date : Jan 01, 2011
Study Type : Review
Additional Links
Diseases : Acne, Cancers: All, Diabetes Mellitus: Type 1, Hyperinsulinism, Insulin: Elevated
Anti Therapeutic Actions : Western Diet
Problem Substances : Cow Milk, Insulin
Adverse Pharmacological Actions : Insulinotropic
[+]

Flavonoids are capable of inhibiting insulin-stimulated glucose uptake in fat cells. Jan 01, 2004

Pubmed Data : J Med Food. 2004;7(1):38-44. PMID: 18591783
Article Published Date : Jan 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Apigenin, Fisetin, Flavonoids, Kaempferol, Luteolin, Quercetin
Diseases : Hyperinsulinism, Obesity, Weight Problems
Pharmacological Actions : Hypoglycemic Agents
[+]

Raisins have the potential to significantly reduce the risk for developing diabetes or cardiovascular disease.May 31, 2013

Pubmed Data : J Food Sci. 2013 Jun ;78 Suppl 1:A11-7. PMID: 23789931
Article Published Date : May 31, 2013
Study Type : Review
Additional Links
Substances : Raisins
Diseases : Cardiovascular Diseases, Hyperinsulinism
Pharmacological Actions : Antihypertensive Agents, Cardioprotective, Hypolipidemic
Additional Keywords : Risk Reduction
[+]

The artificial sweeteners sodium cyclamate, aspartame, acesulfame potassium, and saccharin have insulin-releasing action on pancreatic beta cells. Nov 01, 1998

Pubmed Data : Cell Signal. 1998 Nov;10(10):727-33. PMID: 9884024
Article Published Date : Nov 01, 1998
Study Type : In Vitro Study
Additional Links
Diseases : Hyperinsulinism
Problem Substances : Acesulfame potassium , Artificial Sweeteners, Saccharin, Sodium Cyclamate
[+]

Vanillic acid mitigates the impairments in glucose metabolism in HepG2 cells through BAD-GK interaction during hyperinsulinemia.May 31, 2021

Pubmed Data : J Biochem Mol Toxicol. 2021 Jun ;35(6):1-8. Epub 2021 Mar 2. PMID: 33651899
Article Published Date : May 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Vanillic Acid
Diseases : Hyperinsulinism
[+]

Wheat germ agglutinin (WGA) and concanavalin A exhibit insulin-mimetic properties.Apr 01, 1987

Pubmed Data : Arch Biochem Biophys. 1987 Apr;254(1):110-5. PMID: 3555340
Article Published Date : Apr 01, 1987
Study Type : In Vitro Study
Additional Links
Diseases : Hyperinsulinism, Insulin Disorders, Insulin Resistance
Additional Keywords : Insulin Mimetic
Problem Substances : Concanavalin A, Wheat Germ Agglutinin (WGA)

Copyright: designua / 123RF Stock Photo

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