Intima Media Thickening

Name	AC	CK
Niacin	2	20
Pomegranate	2	20
Arginine	3	14
B-complex	1	10
Fiber	1	10
Folic Acid	1	10
Garlic	1	10
Modified Citrus Pectin	1	10
NAC (N-acetyl-L-cysteine)	1	10
Polyphenols	1	10
Isoflavones	2	4
Nattokinase	2	4
Policosanol	2	4
Alfalfa	1	2
Astaxanthin	1	2
Berberine	1	2
Curcumin	1	2
Cysteine (see N-Acetylcysteine)	1	2
Fermented Foods and Beverages	1	2
Fucoidan	1	2
Kimchi	1	2
Lecithin	1	2
Magnesium	1	2
Natto	1	2
Nutmeg	1	2
Sesame Seed Oil	1	2
Soy	1	2
Soy Protein	1	2
Ashwagandha	1	1
Bacopa	1	1
Green Tea	1	1
Milk Thistle	1	1
Protandim	1	1
Turmeric	1	1
Vitamin E	1	1

Name	AC	CK	Focus
Aluminum	1	10

Name	AC	CK	Focus
Oophorectomy (Ovariectomy)	1	10

[+]

"Circulating levels of metals are related to carotid atherosclerosis in elderly."Dec 15, 2011

Click here to read the entire abstract

Pubmed Data : Sci Total Environ. 2011 Dec 15. Epub 2011 Dec 15. PMID: 22178028

Article Published Date : Dec 15, 2011

Study Type : Human Study

Additional Links

Diseases : Atherosclerosis, Intima Media Thickening

Problem Substances : Aluminum

Adverse Pharmacological Actions : Cardiotoxic

[+]

A B vitamin formula decreases the carotid artery thickness in patients at risk for cerebral ischemia. Jul 01, 2005

Click here to read the entire abstract

Pubmed Data : Atherosclerosis. 2005 Jul;181(1):131-5. Epub 2005 Feb 16. PMID: 15939064

Article Published Date : Jul 01, 2005

Study Type : Human Study

Additional Links

Substances : B-complex

Diseases : Carotid Artery Narrowing, Hyperhomocysteinemia, Intima Media Thickening

[+]

Extended-release niacin significantly increases HDL-C and induces atherosclerosis regression in statin treatment. Nov 01, 2006

Click here to read the entire abstract

Pubmed Data : Curr Med Res Opin. 2006 Nov;22(11):2243-50 PMID: 17076985

Article Published Date : Nov 01, 2006

Study Type : Human Study

Additional Links

Substances : Niacin

Diseases : Intima Media Thickening

[+]

Folic acid supplementation results in significant intima media thickness reduction after 18 months in patients with at least one cardiovascular risk.Feb 06, 2009

Click here to read the entire abstract

Pubmed Data : Int J Cardiol. 2009 Feb 6. PMID: 19201496

Article Published Date : Feb 06, 2009

Study Type : Human Study

Additional Links

Substances : Folic Acid

Diseases : Carotid Stenosis, Intima Media Thickening

Additional Keywords : Disease Reversal

[+]

Garlic reduces a multitude of risk factors associated with arteriosclerosis and significantly reduces the risk for heart attack and stroke. Jan 01, 1999

Click here to read the entire abstract

Pubmed Data : Wien Med Wochenschr. 1999;149(8-10):217-24. PMID: 10483684

Article Published Date : Jan 01, 1999

Study Type : Human Study

Additional Links

Substances : Garlic

Diseases : Arterial Plaque, Arteriosclerosis, Fibrinogen: Elevated, Heart Attack, Intima Media Thickening , Myocardial Infarction, Stroke: Prevention

Additional Keywords : Disease Regression

[+]

Long-term N-acetylcysteine and L-arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes.May 01, 2008

Click here to read the entire abstract

Pubmed Data : Diabetes Care. 2008 May;31(5):940-4. Epub 2008 Feb 11. PMID: 18268065

Article Published Date : May 01, 2008

Study Type : Human Study

Additional Links

Substances : Arginine, NAC (N-acetyl-L-cysteine)

Diseases : C-Reactive Protein, Diabetes Mellitus: Type 2, Endothelial Dysfunction, Fibrinogen: Elevated, Hypertension, Intima Media Thickening

Pharmacological Actions : Hypoglycemic Agents, Vascular Cell Adhesion Molecule-1 Inhibitor

[+]

Niacin regresses carotid intimal medial thickness, reduces vascular inflammation and improves endothelial function in patients with metabolic syndrome. Nov 01, 2007

Click here to read the entire abstract

Pubmed Data : Int J Clin Pract. 2007 Nov;61(11):1942-8. PMID: 17935553

Article Published Date : Nov 01, 2007

Study Type : Human Study

Additional Links

Substances : Niacin

Diseases : Carotid Artery Narrowing, Intima Media Thickening , Metabolic Syndrome X

[+]

Oophorectomy adversely affect healthy postmenopausal women by accelerating loss of bone mineral density (BMD) and the rate of increase in carotid artery intima-media thickness (CIMT).Mar 31, 2014

Click here to read the entire abstract

Pubmed Data : Fertil Steril. 2014 Apr ;101(4):1117-22. Epub 2014 Feb 14. PMID: 24530156

Article Published Date : Mar 31, 2014

Study Type : Human Study

Additional Links

Diseases : Atherosclerosis, Carotid Artery Narrowing, Intima Media Thickening , Osteoporosis, Osteoporosis: Age-Related

Additional Keywords : Ovariectomy-Induced Changes

Anti Therapeutic Actions : Oophorectomy (Ovariectomy)

[+]

Pomegranate juice consumption appears to slow the progression of the carotid intima-media thickness in subjects with increased oxidative stress and poor blood lipid profiles. Oct 01, 2009

Click here to read the entire abstract

Pubmed Data : Am J Cardiol. 2009 Oct 1;104(7):936-42. PMID: 19766760

Article Published Date : Oct 01, 2009

Study Type : Human Study

Additional Links

Substances : Polyphenols, Pomegranate

Diseases : Arterial Thickening, Carotid Artery Narrowing, Intima Media Thickening

Pharmacological Actions : Anti-atherogenic, Antioxidants

[+]

Pomegranate reduces the intima media thickness size of the artery, while also reducing blood pressure and LDL oxidation.Jun 01, 2004

Click here to read the entire abstract

Pubmed Data : Clin Nutr. 2004 Jun;23(3):423-33. PMID: 15158307

Article Published Date : Jun 01, 2004

Study Type : Human Study

Additional Links

Substances : Pomegranate

Diseases : Carotid Stenosis, Cholesterol: Oxidation, Hypertension, Intima Media Thickening

[+]

The intake of viscous fiber, especially pectin, appears to protect against intima media thickness progression.Dec 01, 2003

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2003 Dec;78(6):1085-91. PMID: 14668268

Article Published Date : Dec 01, 2003

Study Type : Human Study

Additional Links

Substances : Fiber, Modified Citrus Pectin

Diseases : Arteriosclerosis, Intima Media Thickening

[+]

Berberine improves neointima formation in a rat model.May 01, 2006

Click here to read the entire abstract

Pubmed Data : Atherosclerosis. 2006 May;186(1):29-37. Epub 2005 Aug 10. PMID:16098530

Article Published Date : May 01, 2006

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Atherosclerosis, Intima Media Thickening

[+]

"Low molecular weight fucoidan prevents intimal hyperplasia in rat injured thoracic aorta through the modulation of matrix metalloproteinase-2 expression."Jan 14, 2011

Click here to read the entire abstract

Pubmed Data : Biochem Pharmacol. 2011 Jan 15 ;81(2):233-43. Epub 2010 Sep 29. PMID: 20887714

Article Published Date : Jan 14, 2011

Study Type : Animal Study

Additional Links

Substances : Fucoidan

Diseases : Aortic Plaques, Intima Media Thickening

Pharmacological Actions : Cardioprotective, Matrix metalloproteinase-2 (MMP-2) inhibitor

[+]

A compound in Kimchi (fermented cabbage) is superior to simvastatin in inhibiting atherosclerosis in rabbits.Dec 12, 2007

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2007 Dec 12;55(25):10486-92. Epub 2007 Nov 16. PMID: 18004805

Article Published Date : Dec 12, 2007

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Kimchi

Diseases : Aortic Plaques, Atherosclerosis, Intima Media Thickening

Additional Keywords : Drug: Simvastatin, Food as Medicine, Hall of Fame, Statin Alternatives, Superiority of Natural Substances versus Drugs

[+]

Alfalfa meal inhibits atherosclerotic plaque in monkeys.Nov 01, 1980

Click here to read the entire abstract

Pubmed Data : Atherosclerosis. 1980 Nov;37(3):433-8. PMID: 98169

Article Published Date : Nov 01, 1980

Study Type : Animal Study

Additional Links

Substances : Alfalfa

Diseases : Atherosclerosis, Intima Media Thickening

[+]

Arginine reduces atheroma (plaque) formation in rabbit vein grafts. Jul 01, 1995

Click here to read the entire abstract

Pubmed Data : J Surg Res. 1995 Jul;59(1):35-42. PMID: 7630134

Article Published Date : Jul 01, 1995

Study Type : Animal Study

Additional Links

Substances : Arginine

Diseases : Atheroma, Atherosclerosis, Intima Media Thickening

[+]

Astanxanthin improves artery thickness and vascular elastin in hypertension.Apr 01, 2006

Click here to read the entire abstract

Pubmed Data : Biol Pharm Bull. 2006 Apr;29(4):684-8. PMID: 16595899

Article Published Date : Apr 01, 2006

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Arterial Hardening: Elasticity, Blood Pressure: High, Intima Media Thickening , Oxidative Stress

Pharmacological Actions : Anti-atherogenic, Antihypertensive Agents, Cardioprotective

[+]

Curcumin significantly attenuates carotid artery neointima formation. Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Arterioscler Thromb Vasc Biol. 2006 Jan;26(1):85-90. Epub 2005 Oct 20. PMID: 16239599

Article Published Date : Jan 01, 2006

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Arteriosclerosis, Carotid Artery Narrowing, Carotid Stenosis, Intima Media Thickening

[+]

Dietary supplementation of fermented soybean, natto, suppresses intimal thickening after endothelial injury in rat femoral arteryJul 25, 2003

Click here to read the entire abstract

Pubmed Data : Life Sci. 2003 Jul 25;73(10):1289-98. PMID: 12850244

Article Published Date : Jul 25, 2003

Study Type : Animal Study

Additional Links

Substances : Nattokinase, Soy

Diseases : Arteriosclerosis, Intima Media Thickening

[+]

Dietary supplementation with fermented soybeans suppresses intimal thickening.Mar 01, 2003

Click here to read the entire abstract

Pubmed Data : Nutrition. 2003 Mar;19(3):261-4. PMID: 12620531

Article Published Date : Mar 01, 2003

Study Type : Animal Study

Additional Links

Substances : Natto , Nattokinase

Diseases : Arteriosclerosis, Intima Media Thickening

Pharmacological Actions : Fibrinolytic Agents

Additional Keywords : Thrombolytic

[+]

Folate supplementation inhibits carotid artery thickening induced by a high-homocysteine diet in a rat model. Sep 01, 2001

Click here to read the entire abstract

Pubmed Data : J Vasc Surg. 2001 Sep;34(3):474-81. PMID: 11533600

Article Published Date : Sep 01, 2001

Study Type : Animal Study

Additional Links

Diseases : Carotid Stenosis, Hyperhomocysteinemia, Intima Media Thickening , Restenosis

[+]

L-arginine prevents endothelial dysfunction in a hypercholesterolemic rabbit model. Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : Lipids Health Dis. 2008;7:27. Epub 2008 Aug 2. PMID: 18673573

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : Arginine

Diseases : Aortic Plaques, Aortic Stenosis, Atherosclerosis, Endothelial Dysfunction, High Cholesterol, Intima Media Thickening

Pharmacological Actions : Apoptotic, Cardioprotective

[+]

Lecithin restores normal blood lipid profile and removal of lipid from established atherosclerotic plaque in rabbits. Feb 01, 1985

Click here to read the entire abstract

Pubmed Data : Br J Exp Pathol. 1985 Feb;66(1):35-46. PMID: 3970829

Article Published Date : Feb 01, 1985

Study Type : Animal Study

Additional Links

Substances : Lecithin

Diseases : Arterial Plaque, Arterial Thickening, Arteriosclerosis, Intima Media Thickening

Additional Keywords : Disease Regression

[+]

Magnesium deficiency may contribute to arterial media thickening.Nov 01, 2000

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2000 Nov;84(5):757-64. PMID: 11177191

Article Published Date : Nov 01, 2000

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Arteriosclerosis, Intima Media Thickening

[+]

N-acetyl cysteine inhibits balloon-induced arterial thickening in a rabbit experimental modelJan 01, 2007

Click here to read the entire abstract

Pubmed Data : Oral Health Prev Dent. 2007;5(4):327-36. PMID: 11341511

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Substances : Cysteine (see N-Acetylcysteine)

Diseases : Arterial Thickening, Intima Media Thickening

[+]

Nutmeg has a cholesterol lowering and plaque dissolving effect in hypercholesterolemic rabbits. Oct 01, 1995

Click here to read the entire abstract

Pubmed Data : Indian J Physiol Pharmacol. 1995 Oct;39(4):407-10. PMID: 8582756

Article Published Date : Oct 01, 1995

Study Type : Animal Study

Additional Links

Substances : Nutmeg

Diseases : Arteriosclerosis, Intima Media Thickening

Additional Keywords : Disease Regression

[+]

Policosanol against neointima formation in this experimental model was slightly better than that of lovastatin.Jul 10, 2009

Click here to read the entire abstract

Pubmed Data : Science. 2009 Jul 10;325(5937):201-4. PMID: 11207063

Article Published Date : Jul 10, 2009

Study Type : Animal Study

Additional Links

Substances : Policosanol

Diseases : Arteriosclerosis, Intima Media Thickening

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Policosanol prevents endothelium injury and reduces significantly intimal thickness of rabbit arteries damaged with forcepsJun 01, 2010

Click here to read the entire abstract

Pubmed Data : J Lipid Res. 2010 Jun;51(6):1416-23. Epub 2010 Jan 13. PMID: 17887938

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Substances : Policosanol

Diseases : Endothelial Dysfunction, Intima Media Thickening

[+]

Sesame seed oil may inhibit atherosclerosis lesion formation. Dec 01, 2006

Click here to read the entire abstract

Pubmed Data : J Med Food. 2006 Winter;9(4) PMID: 17201634

Article Published Date : Dec 01, 2006

Study Type : Animal Study

Additional Links

Substances : Sesame Seed Oil

Diseases : Arteriosclerosis, Intima Media Thickening

[+]

Soy protein containing isoflavones reduces the size of atherosclerotic plaques in adult male monkeys.Dec 01, 2005

Click here to read the entire abstract

Pubmed Data : J Nutr. 2005 Dec;135(12):2852-6. PMID: 16317131

Article Published Date : Dec 01, 2005

Study Type : Animal Study

Additional Links

Substances : Isoflavones, Soy Protein

Diseases : Arterial Plaque, Arteriosclerosis, Coronary Artery Disease, Endothelial Dysfunction, Intima Media Thickening

Pharmacological Actions : Vasodilator Agents

[+]

Soy protein reduces the formation of artherosclerotic lesions in the coronary arteries of male monkeys. Nov 01, 1997

Click here to read the entire abstract

Pubmed Data : Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2524-31. PMID: 9409223

Article Published Date : Nov 01, 1997

Study Type : Animal Study

Additional Links

Substances : Isoflavones

Diseases : Arteriosclerosis, Coronary Artery Disease, Intima Media Thickening

[+]

A multi-herbal product called Protandim attenuates intima hyperplasia. Mar 15, 2011

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2011 Mar 15;50(6):700-9. Epub 2010 Dec 15. PMID: 21167278

Article Published Date : Mar 15, 2011

Study Type : In Vitro Study

Additional Links

Substances : Ashwagandha, Bacopa, Green Tea, Milk Thistle, Protandim, Turmeric

Diseases : Intima Media Thickening

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation

[+]

Lipoproteins (LDL) may be implicated in arteriosclerosis by acting as a nonspecific immune defense against microbial infection, leading to plaque build-up in the artery and an autoimmune-mediated acceleration of the disease process. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Ann Clin Lab Sci. 2009;39(1):3-16. PMID: 19201735

Article Published Date : Jan 01, 2009

Study Type : Commentary

Additional Links

Diseases : Arterial Plaque, Arteriosclerosis, Autoimmune Diseases, Cardiovascular Diseases, Cholesterol: Oxidation, Intima Media Thickening

Additional Keywords : Cholesterol Myth, Diseases that are Linked

[+]

Vitamin E may reduce the progression of atherosclerosis. Nov 15, 1996

Click here to read the entire abstract

Pubmed Data : Circulation. 1996 Nov 15;94(10):2369-72. PMID: 8921775

Article Published Date : Nov 15, 1996

Study Type : Review

Additional Links

Substances : Vitamin E

Diseases : Arteriosclerosis, Intima Media Thickening

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View the Evidence: 34 Abstracts with Intima Media Thickening Research

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"Circulating levels of metals are related to carotid atherosclerosis in elderly."Dec 15, 2011

A B vitamin formula decreases the carotid artery thickness in patients at risk for cerebral ischemia. Jul 01, 2005

Extended-release niacin significantly increases HDL-C and induces atherosclerosis regression in statin treatment. Nov 01, 2006

Folic acid supplementation results in significant intima media thickness reduction after 18 months in patients with at least one cardiovascular risk.Feb 06, 2009

Garlic reduces a multitude of risk factors associated with arteriosclerosis and significantly reduces the risk for heart attack and stroke. Jan 01, 1999

Long-term N-acetylcysteine and L-arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes.May 01, 2008

Niacin regresses carotid intimal medial thickness, reduces vascular inflammation and improves endothelial function in patients with metabolic syndrome. Nov 01, 2007

Oophorectomy adversely affect healthy postmenopausal women by accelerating loss of bone mineral density (BMD) and the rate of increase in carotid artery intima-media thickness (CIMT).Mar 31, 2014

Pomegranate juice consumption appears to slow the progression of the carotid intima-media thickness in subjects with increased oxidative stress and poor blood lipid profiles. Oct 01, 2009

Pomegranate reduces the intima media thickness size of the artery, while also reducing blood pressure and LDL oxidation.Jun 01, 2004

The intake of viscous fiber, especially pectin, appears to protect against intima media thickness progression.Dec 01, 2003

Berberine improves neointima formation in a rat model.May 01, 2006

"Low molecular weight fucoidan prevents intimal hyperplasia in rat injured thoracic aorta through the modulation of matrix metalloproteinase-2 expression."Jan 14, 2011

A compound in Kimchi (fermented cabbage) is superior to simvastatin in inhibiting atherosclerosis in rabbits.Dec 12, 2007

Alfalfa meal inhibits atherosclerotic plaque in monkeys.Nov 01, 1980

Arginine reduces atheroma (plaque) formation in rabbit vein grafts. Jul 01, 1995

Astanxanthin improves artery thickness and vascular elastin in hypertension.Apr 01, 2006

Curcumin significantly attenuates carotid artery neointima formation. Jan 01, 2006

Dietary supplementation of fermented soybean, natto, suppresses intimal thickening after endothelial injury in rat femoral arteryJul 25, 2003

Dietary supplementation with fermented soybeans suppresses intimal thickening.Mar 01, 2003

Folate supplementation inhibits carotid artery thickening induced by a high-homocysteine diet in a rat model. Sep 01, 2001

L-arginine prevents endothelial dysfunction in a hypercholesterolemic rabbit model. Jan 01, 2008

Lecithin restores normal blood lipid profile and removal of lipid from established atherosclerotic plaque in rabbits. Feb 01, 1985

Magnesium deficiency may contribute to arterial media thickening.Nov 01, 2000

N-acetyl cysteine inhibits balloon-induced arterial thickening in a rabbit experimental modelJan 01, 2007

Nutmeg has a cholesterol lowering and plaque dissolving effect in hypercholesterolemic rabbits. Oct 01, 1995

Policosanol against neointima formation in this experimental model was slightly better than that of lovastatin.Jul 10, 2009

Policosanol prevents endothelium injury and reduces significantly intimal thickness of rabbit arteries damaged with forcepsJun 01, 2010

Sesame seed oil may inhibit atherosclerosis lesion formation. Dec 01, 2006

Soy protein containing isoflavones reduces the size of atherosclerotic plaques in adult male monkeys.Dec 01, 2005

Soy protein reduces the formation of artherosclerotic lesions in the coronary arteries of male monkeys. Nov 01, 1997

A multi-herbal product called Protandim attenuates intima hyperplasia. Mar 15, 2011

Lipoproteins (LDL) may be implicated in arteriosclerosis by acting as a nonspecific immune defense against microbial infection, leading to plaque build-up in the artery and an autoimmune-mediated acceleration of the disease process. Jan 01, 2009

Vitamin E may reduce the progression of atherosclerosis. Nov 15, 1996

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Intima Media Thickening

View the Evidence:
34 Abstracts with Intima Media Thickening Research