Iron Overload

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40 Substances Researched for Iron Overload
NameACCKFocus
Green Tea313Locked
Alpha-Lipoic Acid212Locked
Curcuminoids110Locked
Galacto-oligosaccharides110Locked
Rosemary110Locked
Curcumin66Locked
Astragaloside35Locked
Nobiletin 15Locked
Cannabidiol24Locked
Grape Seed Extract24Locked
Vitamin C23Locked
Acacia catechu12Locked
Ashwagandha12Locked
Bamboo12Locked
Berberine12Locked
Caffeic Acid12Locked
Fermented Foods and Beverages12Locked
Flavonoids12Locked
Ginkgo biloba12Locked
Hesperidin12Locked
Huperzine12Locked
Krill12Locked
Mangiferin12Locked
Papaya12Locked
Papaya: Fermented12Locked
Tetrahydrocurcumin12Locked
Vitamin E12Locked
White Tea12Locked
Yellow Sweet Clover (Melilotus officinalis)12Locked
Astaxanthin11Locked
Carotenoids11Locked
Chinese Skullcap 11Locked
EGCG (Epigallocatechin gallate)11Locked
Gastrodin11Locked
Isoliquiritigenin11Locked
Licorice11Locked
Milk Thistle11Locked
Polyphenols11Locked
Quercetin11Locked
beta-Carotene11Locked
2 Problem Substances Researched for Iron Overload
NameACCKFocus
Meat110Locked
Sodium Fluoride12Locked
Related Topics

Iron Overload is a Sub of the following Topic

View the Evidence:
67 Abstracts with Iron Overload Research

[+]

Higher heme iron intake was associated with a higher risk of T2D.Feb 01, 2022

Pubmed Data : Eur J Nutr. 2022 Feb 2. Epub 2022 Feb 2. PMID: 35107626
Article Published Date : Feb 01, 2022
Study Type : Meta Analysis
Additional Links
Diseases : Diabetes Mellitus: Type 2, Iron Overload
Additional Keywords : Risk Factors
[+]

Curcumin supplementation would be effective in alleviating iron overload in patients with β-thalassemia intermedia.Feb 28, 2022

Pubmed Data : Clin Lab. 2022 Mar 1 ;68(3). PMID: 35254032
Article Published Date : Feb 28, 2022
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Iron Overload, Thalassemia
Pharmacological Actions : Iron Chelating Agents
[+]

Curcuminoids supplementation ameliorates iron overload, oxidative stress, hypercoagulability, and inflammation.Jan 02, 2021

Pubmed Data : Ann Hematol. 2021 Jan 3. Epub 2021 Jan 3. PMID: 33388858
Article Published Date : Jan 02, 2021
Study Type : Human Study
Additional Links
Substances : Curcuminoids
Diseases : Inflammation, Iron Overload, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Green tea and rosemary added to foods reduces non-heme iron absorption. Mar 01, 2001

Pubmed Data : Am J Clin Nutr. 2001 Mar;73(3):607-12. PMID: 11237939
Article Published Date : Mar 01, 2001
Study Type : Human Study
Additional Links
Substances : Green Tea, Rosemary
Diseases : Iron Overload
Additional Keywords : Iron Chelation
[+]

Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome.Jan 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gut. 2017 11 ;66(11):1956-1967. Epub 2017 Aug 3. PMID: 28774885
Article Published Date : Jan 10, 2017
Study Type : Human Study
Additional Links
Substances : Galacto-oligosaccharides
Diseases : Iron Overload
Pharmacological Actions : Gastrointestinal Agents
[+]

Red meat consumption was significantly positively associated with ferritin concentrations and myocardial infarction risk.Dec 31, 2017

Pubmed Data : Am J Clin Nutr. 2018 Jan 1 ;107(1):113-119. PMID: 29381787
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Iron Overload
Additional Keywords : Risk Factors
Problem Substances : Meat
[+]

The results of this study indicated that supplementation with 600 mg/d alpha lipoic acid may decrease serum ferritin in β-Thalassemia major.Feb 01, 2021

Pubmed Data : Int J Clin Pract. 2021 Feb 2:e14062. Epub 2021 Feb 2. PMID: 33527721
Article Published Date : Feb 01, 2021
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Iron Overload, Thalassemia
Pharmacological Actions : Antioxidants, Hypolipidemic
[+]

Nobiletin could alleviate iron overload damage in vascular endothelium.Jan 29, 2020

Pubmed Data : Biol Trace Elem Res. 2020 Jan 30. Epub 2020 Jan 30. PMID: 32002792
Article Published Date : Jan 29, 2020
Study Type : Human In Vitro
Additional Links
Substances : Nobiletin
Diseases : Iron Overload
Pharmacological Actions : Antioxidants, Nitric Oxide Enhancer
[+]

Vitamin E prevents lipid peroxidation and iron accumulation in PLA2G6-associated neurodegenerationDec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurobiol Dis. 2022 04 ;165:105649. Epub 2022 Feb 2. PMID: 35122944
Article Published Date : Dec 31, 2021
Study Type : Human In Vitro
Additional Links
Substances : Vitamin E
Diseases : Iron Overload, Neurodegenerative Diseases
Pharmacological Actions : Antioxidants
[+]

Alpha lipoic acid attenuates iron induced oxidative acute kidney injury in rats.Sep 13, 2020

Pubmed Data : Biotech Histochem. 2020 Sep 14:1-9. Epub 2020 Sep 14. PMID: 32921159
Article Published Date : Sep 13, 2020
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Iron Overload, Kidney Damage
Pharmacological Actions : Antioxidants, Renoprotective
[+]

Alpha-lipoic acid possesses excellent iron chelating properties.Jan 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Jan 31 ;20(3). Epub 2019 Jan 31. PMID: 30708965
Article Published Date : Jan 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Iron Overload
Pharmacological Actions : Iron Chelating Agents
[+]

Ameliorating effects of white mulberry on iron-overload-induced oxidative stress and liver fibrosis.Aug 27, 2021

Pubmed Data : Food Chem Toxicol. 2021 Aug 28:112520. Epub 2021 Aug 28. PMID: 34464637
Article Published Date : Aug 27, 2021
Study Type : Animal Study
Additional Links
Substances : White Mulberry
Diseases : Iron Overload, Liver Fibrosis, Oxidative Stress
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
[+]

Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload.Sep 02, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Psychiatry. 2018 Sep 3 ;8(1):176. Epub 2018 Sep 3. PMID: 30177808
Article Published Date : Sep 02, 2018
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Cognitive Decline/Dysfunction, Iron Overload
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Ashwaganda's hepatoprotective properties protects against iron overload toxicity.Nov 01, 2000

Pubmed Data : Phytother Res. 2000 Nov;14(7):568-70. PMID: 11054855
Article Published Date : Nov 01, 2000
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Iron Overload
Pharmacological Actions : Hepatoprotective
[+]

Astragaloside IV protects against iron loading-induced abnormal differentiation of bone marrow mesenchymal stem cells.Jan 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : FEBS Open Bio. 2021 Jan 14. Epub 2021 Jan 14. PMID: 33445204
Article Published Date : Jan 13, 2021
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Iron Overload, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Mesenchymal Stem Cells
[+]

Astragaloside IV protects against retinal iron overload toxicity through iron regulation and the inhibition of MAPKs and NF-κB activation.Dec 31, 2020

Pubmed Data : Toxicol Appl Pharmacol. 2021 01 1 ;410:115361. Epub 2020 Dec 4. PMID: 33285147
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Iron Overload, Macular Degeneration
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Berberine protects the liver and kidneys against ferrous sulfate-induced toxicity by reduction in lipid peroxidation and ability to chelate iron.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2018 May ;21(5):476-482. PMID: 29922427
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Iron Overload
Pharmacological Actions : Antioxidants, Hepatoprotective, Iron Chelating Agents, Renoprotective
[+]

Caffeic acid and ferulic acid can improve toxicological damage caused by iron overload.Nov 28, 2022

Pubmed Data : Drug Chem Toxicol. 2022 Nov 29:1-9. Epub 2022 Nov 29. PMID: 36444844
Article Published Date : Nov 28, 2022
Study Type : Animal Study
Additional Links
Substances : Caffeic Acid, Ferulic acid
Diseases : Iron Overload
Pharmacological Actions : Carbonic Anhydrase Inhibitors
[+]

Caffeic acid protects against iron-induced cardiotoxicity.Jun 05, 2020

Pubmed Data : Biol Trace Elem Res. 2020 Jun 6. Epub 2020 Jun 6. PMID: 32506180
Article Published Date : Jun 05, 2020
Study Type : Animal Study
Additional Links
Substances : Caffeic Acid
Diseases : Iron Overload
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Cannabidiol normalizes caspase 3, synaptophysin, and mitochondrial fission protein DNM1L expression levels in rats with brain iron overload.Jan 31, 2014

Pubmed Data : Mol Neurobiol. 2014 Feb ;49(1):222-33. Epub 2013 Jul 28. PMID: 23893294
Article Published Date : Jan 31, 2014
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Iron Overload, Neurodegenerative Diseases
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Curcumin may represent a new horizon in managing iron overload-induced toxicity as well as in pathological diseases characterized by hepatic iron accumulation.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(7):e0134156. Epub 2015 Jul 31. PMID: 26230491
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Iron Overload, Myelodysplastic Syndromes, Oxidative Stress, Sickle Cell Anemia, Thalassemia
Pharmacological Actions : Antioxidants, Iron Chelating Agents
[+]

Dual action of vitamin C in iron supplement therapeutics for iron deficiency anemia: prevention of liver damage induced by iron overload.Oct 16, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Funct. 2018 Oct 17 ;9(10):5390-5401. PMID: 30272083
Article Published Date : Oct 16, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Anemia: Iron Deficiency, Iron Overload, Liver Damage
Pharmacological Actions : Hepatoprotective
[+]

Galangin mitigates iron overload-triggered liver injury.Oct 14, 2021

Pubmed Data : Life Sci. 2021 Oct 15 ;283:119856. Epub 2021 Jul 27. PMID: 34329667
Article Published Date : Oct 14, 2021
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Inflammation, Iron Overload, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

Ginkgetin may provide neuroprotective therapy for Parkinson's disease and iron metabolism disorder related diseases.Dec 31, 2014

Pubmed Data : Free Radic Res. 2015 ;49(9):1069-80. Epub 2015 Jul 1. PMID: 25968939
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginkgo biloba
Diseases : Iron Overload, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Iron Chelating Agents, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

Grape seed proanthocyanidin extract as a naturally occurring prophylactic treatment for fluoride-induced hepatotoxicity associated with iron overload.Dec 31, 2017

Pubmed Data : J Toxicol Sci. 2018 ;43(5):311-319. PMID: 29743442
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Chemically-Induced Liver Damage, Fluoride Toxicity , Iron Overload
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Sodium Fluoride
[+]

Green tea decreases iron in plasma, eliminates lipid peroxidation in plasma and destroys formation of red blood cell reactive oxygen species. Jul 01, 2008

Pubmed Data : Med Chem. 2008 Jul;4(4):365-70. PMID: 18673149
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Green Tea
Diseases : Iron Overload, Thalassemia
Pharmacological Actions : Antioxidants
[+]

Hesperidin attenuates iron-induced oxidative damage and dopamine depletion in a model of Parkinson's disease.Jan 04, 2018

Pubmed Data : Chem Biol Interact. 2018 Jan 5 ;279:177-186. Epub 2017 Dec 2. PMID: 29191452
Article Published Date : Jan 04, 2018
Study Type : Insect Study
Additional Links
Substances : Hesperidin
Diseases : Iron Overload, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Hibiscus sabdariffa holds therapeutic potential to counter iron neurotoxicity.Jan 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2022 Jan 27 ;11(3). Epub 2022 Jan 27. PMID: 35159249
Article Published Date : Jan 26, 2022
Study Type : Animal Study
Additional Links
Substances : Hibiscus sabdariffa
Diseases : Iron Overload, Multiple Sclerosis
Pharmacological Actions : Neuroprotective Agents
[+]

Hops extract and xanthohumol ameliorate bone loss induced by iron overload via activating Akt/GSK3β/Nrf2 pathway.Jan 31, 2022

Pubmed Data : J Bone Miner Metab. 2022 Feb 1. Epub 2022 Feb 1. PMID: 35106609
Article Published Date : Jan 31, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Iron Overload
Pharmacological Actions : Nrf2 activation, Osteoprotective
[+]

Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload.Sep 07, 2022

Pubmed Data : J Nat Med. 2022 Sep 8. Epub 2022 Sep 8. PMID: 36074228
Article Published Date : Sep 07, 2022
Study Type : Animal Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Iron Overload
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Huperzine A, reduces brain iron overload and alleviates cognitive deficit in mice exposed to chronic intermittent hypoxia.May 31, 2020

Pubmed Data : Life Sci. 2020 Jun 1 ;250:117573. Epub 2020 Mar 21. PMID: 32209423
Article Published Date : May 31, 2020
Study Type : Animal Study
Additional Links
Substances : Huperzine
Diseases : Iron Overload, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

In silico and in vivo protective effect of Morus nigra leaves on oxidative damage induced by iron overload.Oct 17, 2021

Pubmed Data : Drug Chem Toxicol. 2021 Oct 18:1-11. Epub 2021 Oct 18. PMID: 34663156
Article Published Date : Oct 17, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Mulberry
Diseases : Iron Overload, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Krill oil might be a new candidate for treatment of iron overload-induced toxicity.Jan 31, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Feb ;27(4):3950-3961. Epub 2019 Dec 10. PMID: 31823254
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Krill
Diseases : Iron Overload, Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Nrf2 activation
[+]

M. officinalis demonstrated dose dependant in-vitro iron chelating ability.Nov 30, 2016

Pubmed Data : Drug Res (Stuttg). 2016 Dec ;66(12):618-627. Epub 2016 Sep 14. PMID: 27626608
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Yellow Sweet Clover (Melilotus officinalis)
Diseases : Iron Overload
Pharmacological Actions : Iron Chelating Agents
Additional Keywords : Plant Extracts
[+]

Mangiferin could increase urinary iron excretion and to decrease iron accumulation in liver and heart.Sep 05, 2018

Pubmed Data : Drug Res (Stuttg). 2018 Sep 6. Epub 2018 Sep 6. PMID: 30189460
Article Published Date : Sep 05, 2018
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Iron Overload
[+]

Naringenin protects against iron overload-induced osteoarthritis by suppressing oxidative stress.Sep 30, 2022

Pubmed Data : Phytomedicine. 2022 Oct ;105:154330. Epub 2022 Jul 14. PMID: 35905566
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Iron Overload, Osteoarthritis
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Nrf2 activation
[+]

Naringin has a strong iron chelation capacity and is able to reduce the formation of amyloid plaques.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:651156. Epub 2021 Jul 2. PMID: 34276359
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Alzheimer's Disease, Iron Overload
Pharmacological Actions : Iron Chelating Agents, Neuroprotective Agents
[+]

Phyllostachys nigra stem can exert a hepatoprotective effect against iron overload-induced acute liver damage due to its antioxidant properties.Jan 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Jan 8 ;11(1). Epub 2019 Jan 8. PMID: 30626086
Article Published Date : Jan 07, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Bamboo
Diseases : Chemically-Induced Liver Damage, Iron Overload, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation
[+]

Protective effect of fucoidan against iron overload and ferroptosis-induced liver injury.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Sep ;153:113402. Epub 2022 Jul 14. PMID: 36076527
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Alcohol Toxicity , Iron Overload, Liver Damage
Pharmacological Actions : Hepatoprotective
[+]

Protective effects of grape seed proanthocyanidins against iron overload-induced renal oxidative damage in rats.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Trace Elem Med Biol. 2020 Jan ;57:126407. Epub 2019 Sep 18. PMID: 31570250
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Iron Overload, Kidney Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Renoprotective
Additional Keywords : Proanthocyanidins
[+]

Puerarin protects against iron overload-induced retinal injury through regulation of iron-handling proteins.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Feb ;122:109690. Epub 2019 Nov 28. PMID: 31786468
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Iron Overload
[+]

Silymarin prevents iron overload induced bone lossSep 30, 2022

Pubmed Data : Chem Biol Interact. 2022 Oct 1 ;366:110168. Epub 2022 Sep 7. PMID: 36087815
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Substances : Silibinin
Diseases : Iron Overload, Osteoporosis, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Study of the protective effects of Katha (Heartwood Extract of Acacia catechu) in liver damage induced by iron overload.Dec 31, 2012

Pubmed Data : J Environ Pathol Toxicol Oncol. 2013 ;32(3):229-40. PMID: 24266409
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Acacia catechu
Diseases : Chemically-Induced Liver Damage, Iron Overload, Lipid Peroxidation
Pharmacological Actions : Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Taxifolin ameliorates iron overload-induced hepatocellular injury.Sep 30, 2020

Pubmed Data : Chem Biol Interact. 2020 Oct 1 ;330:109230. Epub 2020 Aug 20. PMID: 32828744
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Chemically-Induced Liver Damage, Inflammation, Iron Overload
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The antioxidant effect of fermented papaya preparation involves iron chelation.Mar 31, 2012

Pubmed Data : J Biol Regul Homeost Agents. 2012 Apr-Jun;26(2):203-10. PMID: 22824747
Article Published Date : Mar 31, 2012
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Papaya, Papaya: Fermented
Diseases : Iron Overload
Pharmacological Actions : Antioxidants, Iron Chelating Agents
[+]

The effects of Hippophae rhamnoides in neuroprotection and behavioral alterations against iron-induced epilepsy.Aug 31, 2021

Pubmed Data : Epilepsy Res. 2021 Sep ;175:106695. Epub 2021 Jun 24. PMID: 34186382
Article Published Date : Aug 31, 2021
Study Type : Animal Study
Additional Links
Substances : Sea buckthorn
Diseases : Epilepsy, Iron Overload
Pharmacological Actions : Neuroprotective Agents
[+]

These results suggest beneficial effects of Tetrahydrocurcumin and L1 on iron-induced oxidative stress, hypertension, and vascular dysfunction.Nov 30, 2016

Pubmed Data : Vascul Pharmacol. 2016 Dec ;87:199-208. Epub 2016 Oct 3. PMID: 27713040
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Tetrahydrocurcumin
Diseases : Hypertension, Iron Overload, Oxidative Stress
Pharmacological Actions : Antihypertensive Agents
[+]

Treatment of berberine alleviates diabetic nephropathy by reducing iron overload and inhibiting oxidative stress.Feb 23, 2023

Pubmed Data : Histol Histopathol. 2023 Feb 24:18599. Epub 2023 Feb 24. PMID: 36861878
Article Published Date : Feb 23, 2023
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Diabetic Nephropathy, Iron Overload
Pharmacological Actions : Anti-Fibrotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Renoprotective
[+]

Vitamin E attenuates oxidative stress associated with iron overload in rats. Feb 15, 1999

Pubmed Data : Toxicology. 1999 Feb 15;132(2-3):179-86. PMID: 10433381
Article Published Date : Feb 15, 1999
Study Type : Animal Study
Additional Links
Substances : Vitamin E
Diseases : Iron Overload, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

White tea consumption slightly reduces iron absorption in animals.Aug 31, 2011

Pubmed Data : J Physiol Biochem. 2011 Sep ;67(3):331-7. Epub 2011 Feb 19. PMID: 21336649
Article Published Date : Aug 31, 2011
Study Type : Animal Study
Additional Links
Substances : White Tea
Diseases : Iron Overload
Pharmacological Actions : Iron Chelating Agents
Additional Keywords : Plant Extracts
[+]

Astaxanthin reduces iron-induced oxidative damage. Oct 19, 2001

Pubmed Data : Biochem Biophys Res Commun. 2001 Oct 19;288(1):225-32. PMID: 11594777
Article Published Date : Oct 19, 2001
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin, beta-Carotene, Carotenoids, Vitamin C
Diseases : Iron Overload, Iron Poisoning, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Curcumin is an iron chelator. - Article 1. Apr 01, 2006

Pubmed Data : Free Radic Biol Med. 2006 Apr 1;40(7):1152-60. PMID: 16545682
Article Published Date : Apr 01, 2006
Study Type : Commentary
Additional Links
Substances : Curcumin
Diseases : Iron Overload
[+]

Curcumin is an iron chelator. - Article 2.Nov 01, 2004

Pubmed Data : J Eur Acad Dermatol Venereol. 2004 Nov;18(6):649-53. PMID: 18815282
Article Published Date : Nov 01, 2004
Study Type : Commentary
Additional Links
Substances : Curcumin
Diseases : Iron Overload, Iron Poisoning
[+]

Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells.Jan 01, 2009

Pubmed Data : Liver Int. 2009 Jan;29(1):63-72. Epub 2008 May 19. PMID: 18492020
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Iron Overload, Iron Poisoning, Oxidative Stress
Pharmacological Actions : Hepatoprotective
[+]

Gastrodin can inhibit H2O2-induced ferroptosis through its antioxidative effect in C6 cells.Dec 31, 2019

Pubmed Data : Biol Pharm Bull. 2020 ;43(3):480-487. PMID: 32115506
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Gastrodin
Diseases : Hydrogen Peroxide Induced Toxicity, Iron Overload, Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Iron modulatory property of a polysaccharide from Indian medicinal plant Ocimum sanctum.Jan 05, 2021

Pubmed Data : Free Radic Res. 2021 Jan 6:1-10. Epub 2021 Jan 6. PMID: 33327808
Article Published Date : Jan 05, 2021
Study Type : In Vitro Study
Additional Links
Substances : Holy Basil
Diseases : Iron Overload
Pharmacological Actions : Anti-Apoptotic
Additional Keywords : Polysaccharides
[+]

Isoliquiritigenin (ILQ), a flavonoid compound found within licorice, protects mitochondria against iron-catalyzed oxidative stress. Dec 21, 2009

Pubmed Data : Biochem Pharmacol. 2009 Dec 21. Epub 2009 Dec 21. PMID: 20026081
Article Published Date : Dec 21, 2009
Study Type : In Vitro Study
Additional Links
Substances : Isoliquiritigenin, Licorice
Diseases : Iron Overload, Iron Poisoning
Pharmacological Actions : Antioxidants
[+]

Luteoloside protects the vascular endothelium against iron overload injury.Dec 31, 2021

Pubmed Data : Chin J Nat Med. 2022 Jan ;20(1):22-32. PMID: 35101247
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Honeysuckle
Diseases : Endothelial Dysfunction, Iron Overload
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cytoprotective
[+]

Polyphenols such as curcumin and EGCG from green tea may chelate out iron from the Alzheimers brain. Aug 01, 2007

Pubmed Data : Prog Neurobiol. 2007 Aug;82(6):348-60. Epub 2007 Jun 19. PMID: 17659826
Article Published Date : Aug 01, 2007
Study Type : Commentary
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Green Tea, Polyphenols
Diseases : Alzheimer's Disease, Iron Overload
[+]

Protective effect of astragaloside IV on hepatic injury induced by iron overload.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:3103946. Epub 2019 Jul 25. PMID: 31428632
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Chemically-Induced Liver Damage, Iron Overload
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective
[+]

Quercetin protects the vascular endothelium against iron overload damages.Feb 04, 2020

Pubmed Data : Eur J Pharmacol. 2020 Feb 5 ;868:172885. Epub 2019 Dec 20. PMID: 31870832
Article Published Date : Feb 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Iron Overload
Pharmacological Actions : Vasoprotective
[+]

Role of flavonoids in the treatment of iron overload.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2021 ;9:685364. Epub 2021 Jul 5. PMID: 34291050
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Flavonoids
Diseases : Iron Overload
Pharmacological Actions : Iron Chelating Agents
[+]

Silybin, a compound from within milk thistle, is strong iron chelator. Jun 01, 2004

Pubmed Data : Fitoterapia. 2004 Jun;75(3-4):375-7. PMID: 11410232
Article Published Date : Jun 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Milk Thistle
Diseases : Cooley's Anemia, Iron Overload, Iron Poisoning
Additional Keywords : Iron Chelation
[+]

The beneficial effects of statin drugs be related to their action on iron metabolism. Oct 23, 2012

Pubmed Data : QJM. 2012 Oct 24. Epub 2012 Oct 24. PMID: 23097387
Article Published Date : Oct 23, 2012
Study Type : Review
Additional Links
Diseases : Atherosclerosis, Iron Overload
Additional Keywords : Cholesterol Myth
[+]

The major bioactive compound found within Chinese skullcap is an iron chelator and radical scavenger. Mar 01, 2009

Pubmed Data : J Inorg Biochem. 2009 Mar;103(3):326-32. Epub 2008 Nov 19. PMID: 19108897
Article Published Date : Mar 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Iron Overload, Iron Poisoning
Additional Keywords : Iron Chelation
[+]

This study demonstrates that iron depletion causes toxicity for cancer stem cells.Dec 31, 2015

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2016 ;62(4):25-30. Epub 2016 Apr 30. PMID: 27188730
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Iron Overload
Additional Keywords : Cancer Stem Cells
[+]

Curcuminoids alleviate iron overload and lipid peroxidation in thalassemic mice. Sep 01, 2009

Pubmed Data : Med Chem. 2009 Sep 1.PMID:19534681
Article Published Date : Sep 01, 2009
Additional Links
Substances : Curcumin
Diseases : Iron Overload, Thalassemia

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