Kidney Damage: Chemically-Induced

Name	AC	CK
Hesperidin	10	18
Flavonoids	9	16
Quercetin	7	14
Thymoquinone	7	14
Ginger	7	13
Curcumin	6	11
Selenium	6	11
Astaxanthin	5	10
Chrysin	5	10
Naringenin	5	10
Lactoferrin	3	9
Rosemary	5	9
Lycopene	4	8
Melatonin	4	8
Spirulina	4	8
Vitamin C	4	8
Vitamin E	4	8
Apigenin	3	7
Ellagic Acid	3	7
Rutin	3	7
Carvacrol	3	6
Coenzyme Q10	3	6
Dandelion	3	6
Diosgenin	3	6
Diosmin	3	6
Gallic Acid	3	6
Garlic	3	6
Grape Seed Extract	3	6
Luteolin	3	6
Mucuna pruriens (aka Velvet Beans)	3	6
NAC (N-acetyl-L-cysteine)	3	6
Pomegranate	3	6
Royal Jelly	3	6
Zinc	3	6
EGCG (Epigallocatechin gallate)	3	5
Ferulic acid	2	5
Moringa oleifera	3	5
Polyphenols	3	5
Astragaloside	3	4
Beet	2	4
Caffeic acid phenethyl ester	2	4
Flaxseed	2	4
Ginkgo biloba	2	4
Grape	2	4
Green Tea	2	4
Harmine	2	4
Nigella sativa (aka Black Seed)	2	4
Propolis: Bee	2	4
Rose	2	4
Rosemaric Acid	2	4
Silymarin	2	4
Turmeric	2	4
Oregano	2	3
Papaya	2	3
Safflower	1	3
18β-Glycyrrhetinic Acid	1	2
6-Shogaol	1	2
Alpha-Lipoic Acid	1	2
Anthocyanins	1	2
Apple	1	2
Apple Cider Vinegar	1	2
Avacado	1	2
Bamboo	1	2
Basil	1	2
Bee Pollen	1	2
Bee Venom	1	2
Beta-Caryophyllene	1	2
Betanin	1	2
Betulinic acid	1	2
Bilberry	1	2
Bixin	1	2
Black Tea	1	2
Bromelain	1	2
Caffeine	1	2
Calcium	1	2
Camel Milk	1	2
Carnitine	1	2
Carnosic Acid	1	2
Chlorella (Algae)	1	2
Chlorogenic Acid	1	2
Chokeberry	1	2
Cinnamon	1	2
Cocoa	1	2
Coconut Oil	1	2
Cordyceps Militaris	1	2
Crocetin	1	2
Crocin	1	2
Cysteine (see N-Acetylcysteine)	1	2
Dates	1	2
Echinacea	1	2
Elderberry	1	2
Fennel	1	2
Fenugreek	1	2
Fermented Foods and Beverages	1	2
Feverfew	1	2
Fisetin	1	2
Flaxseed Oil	1	2
Fucoidan	1	2
Fucoxanthin	1	2
Garcinia kola	1	2
Garlic: Aged	1	2
Gastrodin	1	2
Ginseng	1	2
Goji	1	2
Gold (nanoparticles)	1	2
Guduchi	1	2
Holy Basil	1	2
Hydroxytyrosol	1	2
Lactobacillus plantarum	1	2
Lemon	1	2
Lignans	1	2
Ligustrazine	1	2
Magnolol	1	2
Milk Thistle	1	2
Mululuza	1	2
Myricetin	1	2
Nettle	1	2
Nobiletin	1	2
Oleuropein	1	2
Olive Oil	1	2
Olive leaf extract	1	2
Orange	1	2
Organosulfur Compounds	1	2
P-Coumaric Acid	1	2
Passion Flower	1	2
Peppermint	1	2
Persimmon	1	2
Plantago asiatica	1	2
Prickly Pear Cactus	1	2
Pumpkin	1	2
Punicalagin	1	2
Purple Carrots	1	2
Reishi Mushroom	1	2
Rhubarb	1	2
Salvia miltiorrhiza	1	2
Schisandra	1	2
Seaweed	1	2
Sesame Seed Oil	1	2
Sesamol	1	2
Silibinin	1	2
Soursop	1	2
Strawberry	1	2
Tamarind	1	2
Terminalia	1	2
Tetrahydrocurcumin	2	2
Theaflavins	1	2
Thymol	1	2
Tocotrienol: Delta	1	2
Vanillic Acid	1	2
Vanillin	1	2
Vitexins	1	2
White Mulberry	1	2
Wogonin	1	2
Carnosine	1	1
Gingerol	1	1
Ginsenosides	1	1
Puerarin	1	1
Resveratrol	1	1
Saikosaponin	1	1
Ursolic Acid	1	1

Name	AC	CK
Cadmium	38	73
Sodium Fluoride	19	44
Lead	20	37
Glyphosate	13	30
Phthalates	8	23
Arsenic	8	21
Paraquat	7	21
Nano Plastic-and Micro-Particles	10	19
Mercury	9	17
Bisphenol A	9	16
Chlorpyrifos	8	16
Pesticides	7	14
Acrylamide	6	12
Aluminum	5	10
Arsenite	5	10
Dental Amalgams	1	10
Polystyrene nanoparticles	6	10
Ochratoxin A	4	7
Acetaminophen	3	6
Aluminum Chloride	3	6
Paracetamol	3	6
Aflatoxin	2	4
Antibiotics	2	4
Benzo(a)pyrene	2	4
Cypermethrin	2	4
Fluoride	3	4
Thimerosal	2	4
Vancomycin	2	4
Arsenic Trioxide	2	3
Energy Drinks	1	3
Formaldehyde	1	3
Nicotine	2	3
Titanium Dioxide	2	3
Cyclophosphamide	1	2
Dexamethasone	1	2
Ethylene Glycol	1	2
Furan	1	2
Gentamicin	1	2
Monosodium Glutamate (MSG)	1	2
N-nitrosodimethylamine	1	2
Nanoparticles	1	2
Organophosphate Pesticides	1	2
Perfluorooctane sulfonate (PFOS)	1	2
Public Drinking Water	1	2
Pyrethroid insecticide	1	2
Sodium Benzoate	1	2
Sodium Dichromate	1	2
Tap Water	1	2
Titanium Nanoparticles	1	2
Bisphenol S	1	1
Electronic Cigarettes	1	1
Nickel	1	1
Roundup (herbicide)	1	1

Name	AC	CK	Focus
Exercise	1	2

[+]

Evaluation of kidney injury biomarkers in an adult Mexican population environmentally exposed to fluoride and low arsenic levels.Jul 31, 2018

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Pubmed Data : Toxicol Appl Pharmacol. 2018 Aug 1 ;352:97-106. Epub 2018 May 22. PMID: 29800643

Click here to read the entire abstract

Pubmed Data : Environ Pollut. 2022 Dec 14 ;318:120871. Epub 2022 Dec 14. PMID: 36528199

Pubmed Data : Ecotoxicol Environ Saf. 2024 Apr 1 ;274:116195. Epub 2024 Mar 12. PMID: 38479315

Article Published Date : Mar 31, 2024

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Rutin

Diseases : Inflammation, Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective

Problem Substances : Sodium Fluoride

[+]

[+]

6-shogaol and could be a cost-effective candidate for the prevention and treatment of urolithiasis.May 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Saudi J Biol Sci. 2021 Jun ;28(6):3418-3423. Epub 2021 Mar 14. PMID: 34121880

Article Published Date : May 31, 2021

Study Type : Animal Study

Additional Links

Substances : 6-Shogaol

Diseases : Aluminum Toxicity , Kidney Damage: Chemically-Induced, Urolithiasis

Pharmacological Actions : Renoprotective

Problem Substances : Aluminum Chloride

[+]

A novel pharmacological strategy using nanoparticles with glutathione and virgin coconut oil to treat gentamicin-induced acute renal failure.Aug 01, 2024

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Environ Sci Pollut Res Int. 2020 Jun 12. Epub 2020 Jun 12. PMID: 32529628

Article Published Date : Jun 11, 2020

Study Type : Animal Study

Additional Links

Substances : Moringa oleifera

Diseases : Kidney Damage: Chemically-Induced, Lead Poisoning, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Renoprotective

Problem Substances : Lead

[+]

Alleviative effect of melatonin against the nephrotoxicity induced by cadmium exposure.Oct 14, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Gene. 2023 Jul 30 ;875:147502. Epub 2023 May 22. PMID: 37224935

Article Published Date : Jul 29, 2023

Study Type : Animal Study

Additional Links

Substances : Chrysin

Diseases : Inflammation, Kidney Damage: Chemically-Induced, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation, Renoprotective

Problem Substances : Cadmium

[+]

Benefits of Chlorella vulgaris against cadmium chloride-induced hepatic and renal toxicities.Aug 28, 2023

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Pubmed Data : Biochem Res Int. 2023 ;2023:6615863. Epub 2023 Aug 22. PMID: 37649570

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeine, Vanillin

Diseases : Aluminum Toxicity , Kidney Damage: Chemically-Induced

Pharmacological Actions : Antioxidants, Renoprotective

Additional Keywords : Natural Substance Synergy

Problem Substances : Aluminum

[+]

Calcium alleviates fluoride-induced kidney damage.Dec 14, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Tissue Cell. 2021 Sep 27 ;73:101657. Epub 2021 Sep 27. PMID: 34628213

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Pubmed Data : Front Physiol. 2020 ;11:64. Epub 2020 Feb 7. PMID: 32116774

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Med Ther. 2021 Nov 17 ;21(1):282. Epub 2021 Nov 17. PMID: 34789221

Article Published Date : Nov 16, 2021

Study Type : Animal Study

Additional Links

Substances : Mucuna pruriens (aka Velvet Beans)

Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced

Pharmacological Actions : Hepatoprotective, Renoprotective

Additional Keywords : Plant Extracts

[+]

Exposure to fluoride induces apoptosis in the liver, kidney, and heart of Xenopus laevis.Mar 31, 2023

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Pubmed Data : Acta Histochem. 2023 Apr ;125(3):151999. Epub 2023 Mar 9. PMID: 36905872

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Avicenna J Phytomed. 2018 Jul-Aug;8(4):370-379. PMID: 30377595

Article Published Date : Jun 30, 2018

Study Type : Animal Study

Additional Links

Substances : Feverfew

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Antioxidants, Renoprotective

[+]

Flaxseed lignan-Secoisolariciresinol diglucoside may be recommended for clinical trials in the treatment of kidney disorders caused by exposure to mercury.Sep 05, 2019

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Pubmed Data : Mol Biol Rep. 2019 Sep 6. Epub 2019 Sep 6. PMID: 31493285

Article Published Date : Sep 05, 2019

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Pubmed Data : Phytomedicine. 2025 Sep 23 ;148:157305. Epub 2025 Sep 23. PMID: 41038147

Article Published Date : Sep 22, 2025

Study Type : Animal Study

Additional Links

Substances : Hesperidin

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

[+]

Hesperidin protects against aluminum-induced renal injury.Dec 21, 2022

It seems that harmine administration improved kidney injury induced by nicotine.Dec 31, 2018

[+]

NAC is an effective adjunct for preserving mitochondrial homeostasis and reducing remote effects of AKI in environments where BPA exposure is vulnerable.Oct 20, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2019 Oct 21 ;8(10). Epub 2019 Oct 21. PMID: 31640182

Article Published Date : Oct 20, 2019

Study Type : Animal Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Bisphenol Toxicity, Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

Problem Substances : Bisphenol A

[+]

Naringenin alleviates glyphosate-based herbicide kidney injury.Oct 09, 2025

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Pubmed Data : Tissue Cell. 2025 Oct 10 ;98:103181. Epub 2025 Oct 10. PMID: 41086672

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Pubmed Data : J Oleo Sci. 2018 ;67(10):1339-1345. PMID: 30305562

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Pubmed Data : Environ Toxicol. 2024 Jun ;39(6):3746-3759. Epub 2024 Mar 28. PMID: 38546352

Article Published Date : May 31, 2024

Study Type : Animal Study

Additional Links

Substances : Silymarin

Diseases : Aluminum Toxicity , Hyperlipidemia, Kidney Damage: Chemically-Induced, Oxidative Stress

Pharmacological Actions : Antioxidants, Renoprotective

Problem Substances : Aluminum Chloride

[+]

Nephroprotective efficacy of selenium and zinc against potassium dichromate-induced renal toxicity.Jan 22, 2022

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Pubmed Data : Biol Trace Elem Res. 2022 Jan 23. Epub 2022 Jan 23. PMID: 35066750

Article Published Date : Jan 22, 2022

Study Type : Animal Study

Additional Links

Substances : Selenium, Zinc

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

[+]

Nephroprotective role of Beta vulgaris L. root extract against chlorpyrifos-induced renal injury in rats.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:3595761. Epub 2019 Nov 22. PMID: 31885644

Pubmed Data : Environ Sci Pollut Res Int. 2020 Apr 15. Epub 2020 Apr 15. PMID: 32291641

Article Published Date : Apr 14, 2020

Study Type : Animal Study

Additional Links

Substances : Olive leaf extract

Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced

Pharmacological Actions : Hepatoprotective, Renoprotective

[+]

Oral administration of p-coumaric acid significantly protected against cadmium-induced nephrotoxicity.Feb 28, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ren Fail. 2014 Mar ;36(2):244-51. Epub 2013 Sep 24. PMID: 24060003

[+]

Protective effect of hydroxytyrosol against oxidative stress induced by the ochratoxin in kidney cells.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Vet Sci. 2020 ;7:136. Epub 2020 Mar 31. PMID: 32296717

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Pubmed Data : Front Pharmacol. 2024 ;15:1440877. Epub 2024 Jul 12. PMID: 39070780

Article Published Date : Dec 31, 2023

Study Type : Animal Study

Additional Links

Substances : Naringenin

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Antioxidants, Renoprotective

[+]

Protective effect of quercetin and ginger extract against dimethoate potentiated fluoride-induced nephrotoxicity.May 04, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Protective role of astaxanthin against bisphenol A induced biochemical and histopathological alterations in rat kidneys.Dec 31, 2024

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Pubmed Data : Toxicol Mech Methods. 2016 Jul 27:1-6. Epub 2016 Aug 27. PMID: 27464552

Article Published Date : Jul 26, 2016

Study Type : Animal Study

Additional Links

Substances : Punicalagin

Diseases : Kidney Damage: Chemically-Induced, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Renoprotective

[+]

Quercetin alleviates cadmium chloride-induced renal damage.Jul 06, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2021 Jul 7 ;141:111862. Epub 2021 Jul 7. PMID: 34246189

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Pubmed Data : Front Vet Sci. 2023 ;10:1319857. Epub 2023 Nov 16. PMID: 38033639

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Pubmed Data : Environ Sci Pollut Res Int. 2020 May ;27(15):17963-17971. Epub 2020 Mar 12. PMID: 32166689

Article Published Date : Apr 30, 2020

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract

Diseases : Hyperthyroidism, Kidney Damage: Chemically-Induced, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective

[+]

Renoprotective and oxidative stress-modulating effects of taxifolin against cadmium-induced nephrotoxicity.Jul 28, 2022

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Pubmed Data : Bioengineered. 2021 Dec ;12(1):7235-7247. PMID: 34569908

Article Published Date : Nov 30, 2021

Study Type : Animal Study

Additional Links

Substances : Fucoxanthin

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Antioxidants, Renoprotective

Problem Substances : Cadmium

[+]

Role of thymoquinone and ebselen in the prevention of sodium arsenite-induced nephrotoxicity.Dec 16, 2018

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Pubmed Data : Hum Exp Toxicol. 2018 Dec 17:960327118818246. Epub 2018 Dec 17. PMID: 30558456

Article Published Date : Dec 16, 2018

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed), Selenium, Thymoquinone

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Renoprotective

Problem Substances : Arsenite

[+]

Rosemary is efficient in the prevention of kidney function against carbon tetrachloride-toxicity.Nov 29, 2018

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Pubmed Data : Arch Physiol Biochem. 2018 Nov 30:1-8. Epub 2018 Nov 30. PMID: 30501137

Article Published Date : Nov 29, 2018

Study Type : Animal Study

Additional Links

Substances : Rosemary

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Heliyon. 2023 Sep ;9(9):e19678. Epub 2023 Sep 1. PMID: 37809572

Supplementation with fenugreek seeds is significantly effective in protecting the liver and kidneys from carbon tetrachloride toxicity.Mar 31, 2017

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Pubmed Data : Biomed Pharmacother. 2017 Apr ;88:19-26. Epub 2017 Jan 13. PMID: 28092841

Article Published Date : Mar 31, 2017

Study Type : Animal Study

Additional Links

Substances : Fenugreek, Flavonoids

Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced, Lipid Peroxidation

Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective

Additional Keywords : Plant Extracts

[+]

Systemic effects of nanoplastics on multi-organ at the environmentally relevant dose: The insights in physiological, histological, and oxidative damages.Sep 19, 2023

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Pubmed Data : Appl Physiol Nutr Metab. 2018 Aug 7. Epub 2018 Aug 7. PMID: 30086244

Article Published Date : Aug 06, 2018

Study Type : Animal Study

Additional Links

Substances : Prickly Pear Cactus

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

[+]

The novel nephroprotective activity of flaxseed oil on diazinon-induced kidney damage.Feb 28, 2025

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Pubmed Data : Cell Biochem Biophys. 2025 Mar ;83(1):837-843. Epub 2024 Sep 26. PMID: 39325364

Article Published Date : Feb 28, 2025

Study Type : Animal Study

Additional Links

Substances : Flaxseed Oil

Diseases : Kidney Damage: Chemically-Induced, Oxidative Stress, Pesticide Toxicity

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Renoprotective

Problem Substances : Pesticides

[+]

The protective effect of caffeic acid phenethyl ester in the nephrotoxicity induced by α-cypermethrin.Dec 31, 2022

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Pubmed Data : Environ Sci Pollut Res Int. 2021 Jun 11. Epub 2021 Jun 11. PMID: 34117542

Article Published Date : Jun 10, 2021

Study Type : Animal Study

Additional Links

Substances : 18β-Glycyrrhetinic Acid

Diseases : Acrylamide-induced toxicity, Chemically-Induced Liver Damage, Diabetic Complications, Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Renoprotective

Problem Substances : Acrylamide

[+]

The protective effects of Terminalia laxiflora extract on hepato-nephrotoxicity induced by fipronil in male rats.Oct 31, 2020

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Pubmed Data : Environ Sci Pollut Res Int. 2020 Nov ;27(31):39507-39515. Epub 2020 Jul 10. PMID: 32651782

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Pubmed Data : Mol Biol Rep. 2021 Apr ;48(4):3107-3115. Epub 2021 Apr 15. PMID: 33856607

Article Published Date : Mar 31, 2021

Study Type : Animal Study

Additional Links

Substances : Coenzyme Q10

Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced

Pharmacological Actions : Hepatoprotective, Renoprotective

Additional Keywords : Gene Expression Regulation

Problem Substances : Lead

[+]

The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury.Sep 22, 2020

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Pubmed Data : Food Funct. 2020 Sep 23 ;11(9):7456-7467. PMID: 32789347

Article Published Date : Sep 22, 2020

Study Type : Animal Study

Additional Links

Substances : Diosgenin

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Apoptotic, Renoprotective

[+]

Therapeutic potential of Origanum vulgare leaf hydroethanolic extract against renal oxidative stress and nephrotoxicity induced by paraquat.Oct 31, 2019

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Pubmed Data : PLoS One. 2016 ;11(5):e0155190. Epub 2016 May 12. PMID: 27171144

Article Published Date : Dec 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Carnitine

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

Additional Keywords : Carnitine, Kidney Damage: Chemically-Induced, Perfluorooctane sulfonate (PFOS), Renoprotective

Problem Substances : Perfluorooctane sulfonate (PFOS)

[+]

This study suggests that use of natural antioxidants in combination with GNPs may be a useful tool in preventing gold nanoparticles toxicity.Dec 31, 2019

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Pubmed Data : Biotech Histochem. 2020 Mar 24:1-8. Epub 2020 Mar 24. PMID: 32207631

Article Published Date : Mar 23, 2020

Study Type : Animal Study

Additional Links

Substances : Thymoquinone

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Thymoquinone showed protective effects against HgCl2-induced nephrotoxicity.Feb 28, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : ACS Omega. 2022 Mar 1 ;7(8):7370-7379. Epub 2022 Feb 18. PMID: 35252727

Article Published Date : Feb 28, 2022

Zingerone can be used as an effective therapeutic agent for the treatment of drug-induced nephrotoxicity.Dec 31, 2017

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Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:2474831. Epub 2018 Jan 30. PMID: 29636837

Pubmed Data : Toxicon. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31356822

Article Published Date : Jul 25, 2019

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

Problem Substances : Ochratoxin A

[+]

Astragaloside IV alleviates tacrolimus-induced chronic nephrotoxicity.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Vet Sci. 2024 ;11:1424711. Epub 2024 Jun 25. PMID: 38983771

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Pubmed Data : Int J Environ Res Public Health. 2014 ;11(2):2125-47. Epub 2014 Feb 20. PMID: 24562182

Article Published Date : Dec 31, 2013

Study Type : Review

Additional Links

Diseases : Chronic Kidney Disease of Unknown Etiology (CKDu), Kidney Damage: Chemically-Induced, Kidney Diseases

Problem Substances : Glyphosate, Roundup (herbicide)

Adverse Pharmacological Actions : Nephrotoxic

[+]

Hesperidin protects liver and kidney against sodium fluoride-induced toxicity.Sep 14, 2021

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Pubmed Data : Life Sci. 2021 Sep 15 ;281:119730. Epub 2021 Jun 17. PMID: 34147482

Pubmed Data : Toxicol Appl Pharmacol. 2019 Jul 1 ;374:65-76. Epub 2019 Apr 29. PMID: 31047982

Article Published Date : Jun 30, 2019

Study Type : In Vitro Study

Additional Links

Diseases : Kidney Cancer, Kidney Damage: Chemically-Induced, Nicotine/Tobacco Toxicity

Problem Substances : Nicotine

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Origanum majorana showed apparent protective and curative effect on cadmium-induced hepatotoxicity and nephrotoxicity.Jul 31, 2011

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Pubmed Data : Saudi Med J. 2011 Aug ;32(8):797-805. PMID: 21858388

Article Published Date : Jul 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Am J Chin Med. 2020 ;48(5):1141-1157. PMID: 32668974

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective, Renoprotective

[+]

Resveratrol diminishes bisphenol A-induced oxidative stress through TRPM2 channel in the mouse kidney cortical collecting duct cells.Nov 30, 2020

Click here to read the entire abstract

Pubmed Data : J Recept Signal Transduct Res. 2020 Dec ;40(6):570-583. Epub 2020 Jun 9. PMID: 32515636

Article Published Date : Nov 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Bisphenol Toxicity, Kidney Damage: Chemically-Induced, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective

Problem Substances : Bisphenol A

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View the Evidence: 310 Abstracts with Kidney Damage: Chemically-Induced Research

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Evaluation of kidney injury biomarkers in an adult Mexican population environmentally exposed to fluoride and low arsenic levels.Jul 31, 2018

Phthalate exposure increased the risk of early renal impairment in Taiwanese without type 2 diabetes mellitus.Nov 25, 2019

The current study reports higher urinary herbicide levels among sugarcane farmers in Warunagama and Rahathangama.Mar 21, 2021

The results of our study suggest that dental amalgams contribute to ongoing kidney damage.Mar 31, 2013

Lactoferrin attenuated urban particulate matter-induced nephrotoxicity.Dec 13, 2022

Microplastics exposure disrupts nephrogenesis and induces renal toxicity in human iPSC-derived kidney organoids.Jul 30, 2024

Acute kidney injury and hepatitis associated with energy drink consumption: a case report.Jan 28, 2020

Acute kidney injury following exposure to formaldehyde-free hair-straightening products.Apr 30, 2022

Ameliorative effect of traditional polyherbal formulation on TNF-α, IL-1β and Caspase-3 expression in kidneys.Jul 10, 2023

Protective effect of hydroxysafflor yellow A on cyclosporin A-induced renal oxidative stress.Dec 31, 2021

Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization.Mar 31, 2024

Salvia miltiorrhiza polysaccharides alleviates florfenicol induced kidney injury in chicks via inhibiting oxidative stress and apoptosis Feb 22, 2022

The protective effect of chrysin against carbon tetrachloride-induced kidney and liver tissue damage.Apr 29, 2020

"Pomegranate Extract Attenuates Gentamicin-Induced Nephrotoxicity in Rats by Reducing Oxidative Stress."Nov 25, 2012

6-shogaol and could be a cost-effective candidate for the prevention and treatment of urolithiasis.May 31, 2021

A novel pharmacological strategy using nanoparticles with glutathione and virgin coconut oil to treat gentamicin-induced acute renal failure.Aug 01, 2024

Activation of gut metabolite ACSL4/LPCAT3 by microplastics in drinking water mediates ferroptosis via gut-kidney axis.Feb 09, 2025

Aged garlic extract rescues ethephon-induced kidney damage.Jan 31, 2021

Alleviation of lead acetate-induced nephrotoxicity by Moringa oleifera extract.Jun 11, 2020

Alleviative effect of melatonin against the nephrotoxicity induced by cadmium exposure.Oct 14, 2023

Alleviative effects of pinostrobin against cadmium-induced renal toxicity.Dec 31, 2022

Ameliorating effect of Mucuna pruriens seed extract on sodium arsenite-induced testicular toxicity and hepato-renal histopathology in rats.Dec 31, 2022

Ameliorative effect of virgin olive oil against nephrotoxicity following sub-chronic administration of ethephon.Aug 31, 2020

Ameliorative effects of hesperidin against iohexol-induced acute kidney injury.Sep 27, 2025

Ameliorative effects of propolis and royal jelly against CCl4 -induced hepatotoxicity and nephrotoxicity.Nov 22, 2022

Ameliorative impacts of astaxanthin against atrazine-induced renal toxicity through the modulation of ionic homeostasis and Nrf2 signaling pathways in mice.May 31, 2024

Ameliorative role of diallyl disulfide against glycerol-induced nephrotoxicity.Dec 31, 2020

Annona Muricata L. extract restores renal function, oxidative stress, immunohistochemical structure, and gene expression against DMBA.Dec 31, 2023

Anti-oxidant, anti-inflammatory and anti-fibrosis effects of ganoderic acid A on carbon tetrachloride induced nephrotoxicity.Jul 31, 2021

Antioxidant activity of Carica papaya & Persea americana fruits against cadmium induced neurotoxicity, nephrotoxicity, and hepatotoxicity.Nov 01, 2023

Antioxidant and anti-inflammatory potential of vanillic acid improves nephrotoxicity induced by sodium arsenite in mice.Dec 08, 2024

Antioxidant and protective effect of Ocimum basilicum seed extract on renal toxicity induced by carbon tetrachloride.Dec 25, 2023

Antioxidative and anti-inflammatory protective effects of β-caryophyllene against amikacin-induced nephrotoxicity.Dec 31, 2021

Antioxidative, anti-inflammatory and anti-apoptotic action of ellagic acid against lead acetate induced testicular and hepato-renal oxidative damages.May 31, 2022

Apigenin can be used as a promising agent to reduce the renal adverse reaction of Imipenem in clinic.May 27, 2020

Apigenin protects from hepatorenal damage caused by lead acetate.Dec 21, 2022

Apple cider vinegar has the therapeutic potential to protect against renal impairment and attendant malfunction.Nov 30, 2020

AQP2 as a target of lycopene protects against atrazine-induced renal ionic homeostasis disturbance.Jun 07, 2021

Ascorbic acid protects against the nephrotoxicity and apoptosis caused by colistin and affects its pharmacokinetics.Jan 31, 2012

Astaxanthin demonstrates significant renoprotective effects against lithium-induced nephrotoxicity.Mar 31, 2024

Astaxanthin-loaded chitosan nanoparticles attenuate chlorpyrifos-induced nephrotoxicity.Jan 18, 2026

Astragaloside IV may be a promising agent for the treatment of uremia toxin-induced injury. Sep 02, 2018

Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.Feb 28, 2022

Bendiocarb-induced nephrotoxicity in rats and the protective role of vitamins C and E.Dec 22, 2019

Beneficial effects of Chrysin on Cadmium-induced nephrotoxicity.Jul 29, 2023

Benefits of Chlorella vulgaris against cadmium chloride-induced hepatic and renal toxicities.Aug 28, 2023

Betanin significantly ameliorated NaF-induced oxidative stress and inflammation.Feb 28, 2025

Betulinic acid abates N-nitrosodimethylamine-induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney.Oct 31, 2021

Bixin attenuates carbon tetrachloride induced oxidative stress, inflammation and fibrosis in kidney.Dec 31, 2020

Black tea theaflavins could protect against liver and kidney damage.May 17, 2021

Cacao polyphenol extracts could protect animal kidneys against carbon tetrachloride.Dec 31, 2014

Caffeine, vanillin, and their combination could potentially be an effective regimen in managing AlCl3-induced renal toxicity.Dec 31, 2022

Calcium alleviates fluoride-induced kidney damage.Dec 14, 2021

CAPE seems to be effective agent and may be related to its potent antioxidant, anti-inflammatory properties and action as an Nrf2 activator.Aug 31, 2017

Cardiovascular and renal oxidative stress-mediated toxicities associated with bisphenol-A exposures are mitigated by Curcuma longa.Dec 31, 2023

Carnosic acid attenuates cadmium induced nephrotoxicity.Nov 17, 2019

Carvacrol may be a promising protective agent in λ-Cyhalothrin-induced hepatotoxicity and nephrotoxicity.Jun 30, 2023

Carvacrol mitigates vancomycin-induced nephrotoxicity.Nov 30, 2022

Chronic exercise provides renal protective effects with upregulation of fatty acid oxidation in the kidney of high fructose-fed rats.Feb 09, 2020

Chronic exposure to low levels of glyphosate and metals induces kidney dysfunction.Jan 23, 2026

Chronic exposure to polystyrene microplastics induces renal fibrosis.Nov 30, 2024

Chrysin attenuates sodium arsenite-induced nephrotoxicity in rats by suppressing oxidative stress and inflammation.Sep 26, 2021

Chrysin mitigates chromium-induced nephrotoxicity.Dec 31, 2025

Co-exposure to aluminum and acrylamide exhibited synergism and more pronounced toxic effects compared with their individual effects.Apr 08, 2015

Coenzyme Q10 reduces the deleterious cellular side effects of lead acetate.Dec 31, 2019

Combination of fluoride and SO2 induce DNA damage and morphological alterations in male rat kidney.Dec 31, 2017

Combined exposure to cadmium and Polystyrene nanoplastics synergistically caused oxidative stress, ferroptosis and excessive mitophagy ultimately aggravating kidney damage.Sep 14, 2023

Crocetin attenuates the oxidative stress, inflammation and apoptosis in arsenic trioxide-induced nephrotoxic rats.Sep 08, 2020

Crocin has protective activities against ethanol toxic effects in the liver and kidney.Dec 31, 2019

Curcumin decreases dibutyl phthalate-induced renal dysfunction in Kunming mice via inhibiting oxidative stress and apoptosis.Mar 16, 2021

Curcumin functions as an anti-inflammatory and antioxidant agent on arsenic-induced hepatic and kidney injury.Jul 16, 2021

Dexpanthenol and ascorbic acid ameliorate colistin-induced nephrotoxicity.Dec 31, 2020

Kidney Damage: Chemically-Induced

View the Evidence:
310 Abstracts with Kidney Damage: Chemically-Induced Research