Kidney Damage: Chemically-Induced

Name	AC	CK
Cocoa	1	2
Curcumin	1	2
Dates	1	2
EGCG (Epigallocatechin gallate)	1	2
Ginger	1	2
Ginkgo biloba	1	2
Polyphenols	1	2
Pomegranate	1	2
Punicalagin	1	2
Rutin	1	2
Selenium	1	2
Sesame Seed Oil	1	2
Thymoquinone	1	2
Zinc	1	2

Name	AC	CK
Acrylamide	1	2
Aluminum	1	2
Arsenic	1	2
Cadmium	1	2
Cypermethrin	1	2
Gentamicin	1	2
Titanium Dioxide	1	2
Titanium Nanoparticles	1	2
Glyphosate	1	1
Roundup (herbicide)	1	1

Additional Keywords : Drug: Gentamicin

Problem Substances : Gentamicin

Adverse Pharmacological Actions : Nephrotoxic

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Alleviation of lead acetate-induced nephrotoxicity by Moringa oleifera extract.Jun 11, 2020

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Pubmed Data : Environ Sci Pollut Res Int. 2020 Jun 12. Epub 2020 Jun 12. PMID: 32529628

Article Published Date : Jun 11, 2020

Study Type : Animal Study

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Substances : Moringa oleifera

Diseases : Kidney Damage: Chemically-Induced, Lead Poisoning, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Renoprotective

Problem Substances : Lead

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Ameliorative effect of virgin olive oil against nephrotoxicity following sub-chronic administration of ethephon.Aug 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Antimicrob Chemother. 2012 Feb ;67(2):452-9. Epub 2011 Nov 28. PMID: 22127588

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Pubmed Data : Molecules. 2019 Nov 18 ;24(22). Epub 2019 Nov 18. PMID: 31752142

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Additional Keywords : Proanthocyanidins

Problem Substances : Sodium Fluoride

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Hepatoprotective activity and nephroprotective activity of peel extract from three varieties of the passion fruit.Feb 27, 2019

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Pubmed Data : Open Access Maced J Med Sci. 2019 Feb 28 ;7(4):536-542. Epub 2019 Feb 27. PMID: 30894908

Article Published Date : Feb 27, 2019

Study Type : Animal Study

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Substances : Passion Flower

Diseases : Acetaminophen (Tylenol) Toxicity , Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced

Pharmacological Actions : Hepatoprotective, Renoprotective

Additional Keywords : Plant Extracts

Problem Substances : Acetaminophen, Paracetamol

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Melatonin prevents lysosomal destruction of liver tissue.Oct 26, 2020

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Pubmed Data : Chronobiol Int. 2020 Oct 27:1-16. Epub 2020 Oct 27. PMID: 33106037

Article Published Date : Oct 26, 2020

Study Type : Animal Study

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Substances : Melatonin

Diseases : Alcohol Toxicity , Alcoholic Liver Disease, Kidney Damage: Chemically-Induced

Pharmacological Actions : Hepatoprotective, Renoprotective

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Pubmed Data : J Oleo Sci. 2018 ;67(10):1339-1345. PMID: 30305562

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Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:3595761. Epub 2019 Nov 22. PMID: 31885644

Article Published Date : Dec 31, 2018

Study Type : Animal Study

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Substances : Beet

Diseases : Kidney Damage: Chemically-Induced, Pesticide Toxicity

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

Problem Substances : Chlorpyrifos

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Pubmed Data : Ecotoxicol Environ Saf. 2020 Jan 13 ;191:110202. Epub 2020 Jan 13. PMID: 31945511

Article Published Date : Jan 12, 2020

Study Type : Animal Study

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Substances : EGCG (Epigallocatechin gallate)

Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced, Smoking

Pharmacological Actions : Hepatoprotective, Renoprotective

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Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity.Mar 11, 2019

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Pubmed Data : Drug Chem Toxicol. 2019 Mar 12:1-7. Epub 2019 Mar 12. PMID: 30862206

Article Published Date : Mar 11, 2019

Study Type : Animal Study

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Substances : Silymarin

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Renoprotective

Problem Substances : Vancomycin

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Pre-treatment with the extract of F. ananassa could protect the kidney against cadmium chloride-induced acute renal toxicity.May 30, 2017

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Pubmed Data : Biol Trace Elem Res. 2017 May 31. Epub 2017 May 31. PMID: 28567583

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Pubmed Data : Front Vet Sci. 2020 ;7:136. Epub 2020 Mar 31. PMID: 32296717

Article Published Date : Dec 31, 2019

Study Type : Animal Study, In Vitro Study

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Substances : Hydroxytyrosol

Diseases : Kidney Damage: Chemically-Induced, Mycotoxin Toxicity

Pharmacological Actions : Antioxidants, Renoprotective

Problem Substances : Ochratoxin A

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Protective effect of Rheum turkestanicum root against mercuric chloride-induced hepatorenal toxicity in rats.Oct 31, 2018

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Pubmed Data : Avicenna J Phytomed. 2018 Nov-Dec;8(6):488-497. PMID: 30456196

Renal protective effects of grape seed extract treatment against eltroxin-induced hyperthyroidism, kidney damage, and oxidative stress.Apr 30, 2020

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Pubmed Data : Environ Sci Pollut Res Int. 2020 May ;27(15):17963-17971. Epub 2020 Mar 12. PMID: 32166689

Article Published Date : Apr 30, 2020

Study Type : Animal Study

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Substances : Grape Seed Extract

Diseases : Hyperthyroidism, Kidney Damage: Chemically-Induced, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective

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Pubmed Data : Curr Med Chem. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31362685

Article Published Date : Jul 29, 2019

Study Type : Review

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Substances : Carnosine

Diseases : Chronic Kidney Disease (CKD), Diabetic Nephropathy, Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

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Glyphosate's synergistic toxicity in combination with other factors as a cause of chronic kidney disease of unknown origin.Jul 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Saudi Med J. 2011 Aug ;32(8):797-805. PMID: 21858388

Article Published Date : Jul 31, 2011

Study Type : In Vitro Study

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Substances : Oregano

Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced

Pharmacological Actions : Hepatoprotective, Renoprotective

Additional Keywords : Plant Extracts

Problem Substances : Cadmium

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Puerarin restored the impaired autophagic flux in lead-treated rat proximal tubular (rPT) cells.Oct 19, 2016

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Pubmed Data : J Biochem Mol Toxicol. 2016 Oct 20. Epub 2016 Oct 20. PMID: 27762461

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Pubmed Data : J Biomed Sci. 2019 Jan 9 ;26(1):5. Epub 2019 Jan 9. PMID: 30621719

Article Published Date : Jan 08, 2019

Study Type : Review

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Substances : Rosemary

Diseases : Cancers: All, Inflammation, Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, Antioxidants, Antiviral Agents, Neuroprotective Agents, Prophylactic Agents, Renoprotective

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Lead

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Selenium attenuates apoptosis and p-AMPK expressions in fluoride-induced NRK-52E cells.Apr 30, 2019

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Pubmed Data : Environ Sci Pollut Res Int. 2019 May ;26(15):15685-15697. Epub 2019 Apr 4. PMID: 30949948

Article Published Date : Apr 30, 2019

Study Type : In Vitro Study

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Substances : Selenium

Diseases : Fluoride Toxicity , Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Apoptotic, Renoprotective

Problem Substances : Sodium Fluoride

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Tetrahydrocurcumin ameliorates tacrolimus-induced nephrotoxicity via inhibiting apoptosis.Oct 31, 2018

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Pubmed Data : Transplant Proc. 2018 Nov ;50(9):2854-2859. Epub 2018 Mar 16. PMID: 30401411

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View the Evidence: 116 Abstracts with Kidney Damage: Chemically-Induced Research

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Phthalate exposure increased the risk of early renal impairment in Taiwanese without type 2 diabetes mellitus.Nov 25, 2019

Acute kidney injury and hepatitis associated with energy drink consumption: a case report.Jan 28, 2020

The protective effect of chrysin against carbon tetrachloride-induced kidney and liver tissue damage.Apr 29, 2020

"Pomegranate Extract Attenuates Gentamicin-Induced Nephrotoxicity in Rats by Reducing Oxidative Stress."Nov 25, 2012

Alleviation of lead acetate-induced nephrotoxicity by Moringa oleifera extract.Jun 11, 2020

Ameliorative effect of virgin olive oil against nephrotoxicity following sub-chronic administration of ethephon.Aug 31, 2020

Apigenin can be used as a promising agent to reduce the renal adverse reaction of Imipenem in clinic.May 27, 2020

Apple cider vinegar has the therapeutic potential to protect against renal impairment and attendant malfunction.Nov 30, 2020

Ascorbic acid protects against the nephrotoxicity and apoptosis caused by colistin and affects its pharmacokinetics.Jan 31, 2012

Astragaloside IV may be a promising agent for the treatment of uremia toxin-induced injury. Sep 02, 2018

Bendiocarb-induced nephrotoxicity in rats and the protective role of vitamins C and E.Dec 22, 2019

Cacao polyphenol extracts could protect animal kidneys against carbon tetrachloride.Dec 31, 2014

CAPE seems to be effective agent and may be related to its potent antioxidant, anti-inflammatory properties and action as an Nrf2 activator.Aug 31, 2017

Carnosic acid attenuates cadmium induced nephrotoxicity.Nov 17, 2019

Chronic exercise provides renal protective effects with upregulation of fatty acid oxidation in the kidney of high fructose-fed rats.Feb 09, 2020

Co-exposure to aluminum and acrylamide exhibited synergism and more pronounced toxic effects compared with their individual effects.Apr 08, 2015

Coenzyme Q10 reduces the deleterious cellular side effects of lead acetate.Dec 31, 2019

Crocetin attenuates the oxidative stress, inflammation and apoptosis in arsenic trioxide-induced nephrotoxic rats.Sep 08, 2020

Crocin has protective activities against ethanol toxic effects in the liver and kidney.Dec 31, 2019

Diosmin protects against trichloroethylene-induced renal injury.Jul 31, 2013

Disruption of kidney metabolism in rats after subchronic combined exposure to low-dose cadmium and chlorpyrifos.Nov 29, 2018

Early kidney damage induced by subchronic exposure to Particulate matter.Jan 11, 2016

Effects of delta-tocotrienol on ochratoxin A-induced nephrotoxicity.Oct 31, 2018

EGCG could attenuate cadmium induced chronic renal injury.Jul 25, 2016

Fermented camel milk prevents carbon tetrachloride induced acute injury in kidney of mice.Apr 30, 2018

Feverfew extract had potent nephroprotective effects against oxygen free radicals produced through carbon tetrachloride metabolism.Jun 30, 2018

Flaxseed lignan-Secoisolariciresinol diglucoside may be recommended for clinical trials in the treatment of kidney disorders caused by exposure to mercury.Sep 05, 2019

Gallic acid could alleviate the noxious effects of paraquat on the antioxidant defense system and renal tissue.Jul 29, 2020

Ginger and zinc mixture protected against malathion induced toxicity to the liver and kidney.Feb 28, 2015

Ginger extracts could have a potent protective effects against nephrotoxicity induced by various toxicants.Jan 31, 2019

Ginkgo biloba extract had a protective effect on lead-induced morphometric changes in the kidneys of albino rats.Dec 31, 2016

Ginkgo biloba extract reverses the renal effects of titanium dioxide nanoparticles in adult male rats.Dec 31, 2015

Grape seed extract has beneficial effects against dexamethasone-induced hepatic and renal dysfunction.Apr 10, 2017

Grape seed procyanidin extract attenuate sodium fluoride-induced oxidative damage and apoptosis in rat kidneys.Jun 19, 2020

Hepatoprotective activity and nephroprotective activity of peel extract from three varieties of the passion fruit.Feb 27, 2019

Hesperidin has a protective effect on sodium arsenite-induced nephrotoxicity and hepatotoxicity.Jul 30, 2018

Influence of ferulic acid consumption in ameliorating the cadmium-induced liver and renal oxidative damage in rats.Jun 30, 2019

Inhibitory activity of flaxseed oil against cadmium chloride induced liver and kidney damage.Dec 31, 2019

It seems that harmine administration improved kidney injury induced by nicotine.Dec 31, 2018

Lycopene attenuates AFB1-induced renal injury with the activation of the Nrf2 antioxidant signaling pathway in mice.Dec 12, 2018

Maintenance of mitochondrial function by astaxanthin protects against bisphenol A-induced kidney toxicity in rats.Nov 12, 2019

Melatonin prevents lysosomal destruction of liver tissue.Oct 26, 2020

Mentha piperita leaf essential oil protects liver and kidney from carbon carbon tetrachloride induced oxidative stress.Jan 08, 2018

N-acetylcysteine and thymoquinone have renoprotective effects of against the toxicity of fluoride via multiple mechanisms.Dec 31, 2017

NAC is an effective adjunct for preserving mitochondrial homeostasis and reducing remote effects of AKI in environments where BPA exposure is vulnerable.Oct 20, 2019

Nephroprotection of plantamajoside in rats treated with cadmium.Dec 31, 2014

Nephroprotective and antioxidant effect of green tea against nicotine-induced nephrotoxicity Feb 24, 2019

Nephroprotective effect of essential oils from ginger and turmeric rhizomes against cadmium-induced nephrotoxicity.Dec 31, 2017

Nephroprotective effect of green tea, rosmarinic acid and rosemary on N-diethylnitrosamine initiated and ferric nitrilotriacetate promoted acute renal toxicity.Sep 30, 2019

Nephroprotective effect of wogonin against cadmium-induced nephrotoxicity.May 27, 2019

Nephroprotective role of Beta vulgaris L. root extract against chlorpyrifos-induced renal injury in rats.Dec 31, 2018

Nephroprotective role of bromelain against oxidative injury induced by aluminium.Oct 31, 2020

Olive leaf extract modulates glycerol-induced kidney and liver damage.Apr 14, 2020

Oral administration of p-coumaric acid significantly protected against cadmium-induced nephrotoxicity.Feb 28, 2014

Oxidative damage and alterations in antioxidant enzyme activities in the kidneys of rat exposed to trichloroacetic acid: protective role of date palm fruit.May 31, 2014

Pomegranate peel extract protects against carbon tetrachloride-induced nephrotoxicity.Aug 31, 2020

Potential ameliorative effects of epigallocatechin-3-gallate against cigarette smoke exposure induced renal and hepatic deficits.Jan 12, 2020

Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity.Mar 11, 2019

Pre-treatment with the extract of F. ananassa could protect the kidney against cadmium chloride-induced acute renal toxicity.May 30, 2017

Propolis extract has a potential protective effect against ethylene glycol induced hepatotoxicity and nephrotoxicity.Sep 30, 2016

Protective effect of cinnamon against acetaminophen-mediated cellular damage and apoptosis in renal tissue.Dec 31, 2018

Protective effect of grape and apple juices against cadmium intoxication in the kidney. Aug 19, 2020

Protective effect of hydroxytyrosol against oxidative stress induced by the ochratoxin in kidney cells.Dec 31, 2019

Protective effect of Rheum turkestanicum root against mercuric chloride-induced hepatorenal toxicity in rats.Oct 31, 2018

Protective effect of rosemary against diethylnitrosamine-induced renal injury.Mar 11, 2020

Protective effect of Spirulina platensis against physiological, ultrastructural and cell proliferation damage induced by furan in kidney and liver.Jan 30, 2020

Protective effects of anthocyanins from bilberry extract in rats exposed to nephrotoxic effects of carbon tetrachloride.Feb 26, 2019

Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in the kidneys.Jun 28, 2020

Protective effects of gomisin A isolated from Schisandra chinensis against CCl(4)-induced hepatic and renal injury.Mar 31, 2013

Protective effects of hesperidin and diosmin against acrylamide-induced liver, kidney, and brain oxidative damage.Nov 30, 2019

Protective effects of spirulina against hemato-biochemical alterations, nephrotoxicity, and DNA damage upon lead exposition.Jan 30, 2020

Protective role of luteolin against bisphenol A-induced renal toxicity.May 14, 2019

Kidney Damage: Chemically-Induced

View the Evidence:
116 Abstracts with Kidney Damage: Chemically-Induced Research