Laryngeal Cancer

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37 Substances Researched for Laryngeal Cancer
NameACCKFocus
Flavan-3-ols120Locked
Flavonoids413Locked
Arginine110Locked
Folate: Dietary110Locked
Folic Acid 110Locked
Fruit: All110Locked
Gc protein-derived macrophage activating factor (GcMAF)110Locked
Omega-3 Fatty Acids110Locked
Vegetables: All 110Locked
Zinc110Locked
Apigenin12Locked
Berberine22Locked
Cucurbitacin B 12Locked
Cucurbitacin E 12Locked
Indole-3-Carbinol12Locked
Oridonin22Locked
Tanshinone IIA12Locked
Andrographis11Locked
Bee Propolis11Locked
Betulinic acid11Locked
Caffeic acid phenethyl ester11Locked
Fisetin11Locked
Genistein11Locked
Luteolin11Locked
Maitake Mushroom11Locked
Mulberry11Locked
Noni11Locked
Potato11Locked
Red Marine Algae11Locked
Reishi Mushroom11Locked
S-Adenosylmethionine (SAMe)11Locked
Seaweed: Brown 11Locked
Shiitake Mushroom 11Locked
Vitamin C11Locked
Wheat Grass11Locked
Xanthohumol11Locked
Zerumbone11Locked
1 Problem Substances Researched for Laryngeal Cancer
NameACCKFocus
Bisphenol A 11Locked
1 Therapeutic Actions Researched for Laryngeal Cancer
NameACCKFocus
Hyperbaric Treatment213Locked

View the Evidence:
40 Abstracts with Laryngeal Cancer Research

[+]

These analysis indicates the potential benefits of flavan-3-ols in cancer prevention.Nov 07, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Nov 8 ;7(45):73573-73592. PMID: 27634884
Article Published Date : Nov 07, 2016
Study Type : Meta Analysis
Additional Links
Substances : Flavan-3-ols
Diseases : Laryngeal Cancer, Rectal Cancer
Pharmacological Actions : Chemopreventive
[+]

The clinical cases presented here reinforce the hypothesis that GcMAF could become part of anticancer immunotherapeutic regimens.Jul 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncoimmunology. 2013 Aug 1 ;2(8):e25769. Epub 2013 Jul 29. PMID: 24179708
Article Published Date : Jul 31, 2013
Study Type : Human Study
Additional Links
Substances : Gc protein-derived macrophage activating factor (GcMAF)
Diseases : Bladder Cancer, Breast Cancer, Follicular Lymphoma, Laryngeal Cancer, Lymphoma, Ovarian Cancer, Prostate Cancer, Tongue Cancer
Pharmacological Actions : Immunomodulatory
Additional Keywords : Nagalase, Significant Treatment Outcome
[+]

A diet rich in fruit and vegetables is inversely related to laryngeal cancer risk.Jan 01, 2010

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2010 Jan;19(1):18-27. PMID: 20056619
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Laryngeal Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

An omega-3 fatty acid and L-arginine supplement improves blood protein concentrations and reduces C-reactive protein in postsurgical patients with head and neck cancer.Jun 01, 2008

Pubmed Data : An Med Interna. 2008 Jun;25(6):275-8. PMID: 19295974
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Arginine, Omega-3 Fatty Acids
Diseases : C-Reactive Protein, Laryngeal Cancer, Oral Cancer
[+]

Hyperbaric oxygen treatment can be an alternative treatment for late-term complications developed after radiotherapy.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Contemp Oncol (Pozn). 2018 ;22(3):202-204. Epub 2018 Sep 30. PMID: 30455593
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Chemotherapy and Radiation Toxicity, Laryngeal Cancer
Therapeutic Actions : Hyperbaric Treatment
Additional Keywords : Significant Treatment Outcome
[+]

Low levels of serum folate were correlated with an increased severity of laryngeal squamous cell carcinoma.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2016 Dec ;12(6):4510-4514. Epub 2016 Oct 14. PMID: 28105160
Article Published Date : Nov 30, 2016
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Folate: Dietary, Folic Acid
Diseases : Folic Acid/Folate Deficiency, Laryngeal Cancer, Squamous cell carcinoma
Additional Keywords : Risk Factors
[+]

Serum zinc concentration appears to be an important prognostic factor for survival of patients diagnosed with laryngeal cancer.Jan 09, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2021 06 10 ;11(6). Epub 2021 Jun 10. PMID: 34200699
Article Published Date : Jan 09, 2021
Study Type : Human Study
Additional Links
Substances : Zinc
Diseases : Laryngeal Cancer, Zinc Deficiency
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Risk Factors
[+]

This study provides support for a beneficial effect of selected flavonoids on laryngeal cancer risk.May 31, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Oncol. 2007 Jun ;18(6):1104-9. Epub 2007 Mar 19. PMID: 17372161
Article Published Date : May 31, 2007
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : Laryngeal Cancer
Pharmacological Actions : Chemopreventive
[+]

Hyperbaric oxygen has been shown to help resolve radiation-induced damage.Jul 31, 2018

Pubmed Data : Harefuah. 2018 Aug ;157(8):486-489. PMID: 30175561
Article Published Date : Jul 31, 2018
Study Type : Human: Case Report
Additional Links
Diseases : Chemotherapy and Radiation Toxicity, Laryngeal Cancer, Prostate Cancer
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Radioprotective
[+]

Spontaneous regression of laryngeal carcinoma in 10 year old boy.Nov 30, 2017

Pubmed Data : Int J Pediatr Otorhinolaryngol. 2017 Dec ;103:10-13. Epub 2017 Oct 5. PMID: 29224746
Article Published Date : Nov 30, 2017
Study Type : Human: Case Report
Additional Links
Diseases : Laryngeal Cancer, Squamous cell carcinoma
Additional Keywords : Spontaneous Regression
[+]

Spontaneous regression of laryngeal squamous cell carcinoma after biopsy.Jul 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ear Nose Throat J. 2020 Jul 15:145561320939834. Epub 2020 Jul 15. PMID: 32668980
Article Published Date : Jul 14, 2020
Study Type : Human: Case Report
Additional Links
Diseases : Laryngeal Cancer
Additional Keywords : Spontaneous Tumor Regression
[+]

Apigenin may improve the radiosensitivity of laryngeal carcinoma by suppressing the expression of GLUT-1 via the PI3K/Akt pathway.Jul 27, 2015

Pubmed Data : Oncol Rep. 2015 Jul 28. Epub 2015 Jul 28. PMID: 26238658
Article Published Date : Jul 27, 2015
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Laryngeal Cancer
Pharmacological Actions : Radiosensitizer
[+]

Cucurbitacin B and cisplatin combination treatment may be a potentially useful therapeutic option for individuals diagnosed with laryngeal cancer.Aug 31, 2010

Pubmed Data : Eur J Pharmacol. 2010 Sep 1 ;641(1):15-22. Epub 2010 May 17. PMID: 20483353
Article Published Date : Aug 31, 2010
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Laryngeal Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Cucurbitacin E has a chemotherapeutic effect on laryngeal cancer stem cells.May 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Laryngoscope Investig Otolaryngol. 2022 Jun ;7(3):723-729. Epub 2022 Mar 24. PMID: 35734072
Article Published Date : May 31, 2022
Study Type : Animal Study
Additional Links
Substances : Cucurbitacin E
Diseases : Laryngeal Cancer
Pharmacological Actions : Antiproliferative , Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin
[+]

Indole-3-carbinol inhibits cell proliferation and induces apoptosis in Hep-2 laryngeal cancer cells.Jun 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Rep. 2013 Jul ;30(1):227-33. Epub 2013 Apr 22. PMID: 23604413
Article Published Date : Jun 30, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Laryngeal Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic
[+]

Tanshinone sensitized the antitumor effects of irradiation on laryngeal cancer via JNK pathway.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Med. 2018 Oct ;7(10):5187-5193. Epub 2018 Sep 21. PMID: 30239172
Article Published Date : Sep 30, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Laryngeal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Radiosensitizer
[+]

Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells.Aug 31, 2020

Pubmed Data : Toxicol In Vitro. 2020 Sep ;67:104885. Epub 2020 May 12. PMID: 32407876
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Laryngeal Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Natural Substance/Drug Synergy
[+]

An extract of potato inhibits a variety of cancer cell lines, as well as Herpes simplex.Sep 01, 2010

Pubmed Data : Fitoterapia. 2010 Sep;81(6):600-6. Epub 2010 Mar 20. PMID: 20227470
Article Published Date : Sep 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Potato
Diseases : Brain Cancer, Breast Cancer, Cancers: Canine, Cervical Cancer, Colon Cancer, Herpes family viruses, Laryngeal Cancer, Leukemia, Liver Cancer
Pharmacological Actions : Antiproliferative , Antiviral Agents
[+]

An extract of wheatgrass inhibits human laryngeal cancer cell proliferation via cell cycle G1 arrest and p53 induction.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2015 May ;11(Suppl 1):S139-47. PMID: 26109759
Article Published Date : Apr 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Wheat Grass
Diseases : Laryngeal Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Plant Extracts
[+]

Andrographolide sensitizes Hep-2 human laryngeal cancer cells to carboplatin-induced apoptosis.Dec 31, 2018

Pubmed Data : Anticancer Drugs. 2019 08 ;30(7):e0774. PMID: 31306153
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Cancers: Drug Resistant, Laryngeal Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Drug Synergy
[+]

Antimicrobial, antioxidant and anticancer activities of Laurencia catarinensis, Laurencia majuscula and Padina pavonica extracts.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi Pharm J. 2018 Jan ;26(1):44-52. Epub 2017 Nov 10. PMID: 29379332
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Red Marine Algae, Seaweed: Brown
Diseases : Aspergillosis, Breast Cancer, Candida Infection , Cervical Cancer, Gastrointestinal Cancer, Laryngeal Cancer, Liver Cancer, Lung Cancer
Pharmacological Actions : Antimicrobial, Antiproliferative
Additional Keywords : Plant Extracts
[+]

Ascorbic acid induces necrotic cell death through ROS generation, PKC activation, and cytosolic calcium signalling.May 21, 2016

Pubmed Data : J Cell Physiol. 2016 May 22. Epub 2016 May 22. PMID: 27211910
Article Published Date : May 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C
Diseases : Laryngeal Cancer, Squamous cell carcinoma
Pharmacological Actions : Cytotoxic
[+]

Berberine inhibits the malignant cell phenotype.Apr 22, 2024

Pubmed Data : Histol Histopathol. 2024 Apr 23:18753. Epub 2024 Apr 23. PMID: 38712806
Article Published Date : Apr 22, 2024
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Laryngeal Cancer, Squamous cell carcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Betulinic acid inhibits the proliferation of human laryngeal carcinoma cells.Dec 04, 2023

Pubmed Data : Toxicol In Vitro. 2023 Dec 5 ;95:105756. Epub 2023 Dec 5. PMID: 38061603
Article Published Date : Dec 04, 2023
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Laryngeal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Bisphenol A triggers proliferation and migration of laryngeal squamous cell carcinoma.May 01, 2017

Pubmed Data : Cell Biochem Funct. 2017 May 2. Epub 2017 May 2. PMID: 28466560
Article Published Date : May 01, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Laryngeal Cancer
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Inflammatory
[+]

Caffeic acid phenethyl ester inhibits the proliferation of HEp2 cells.Jul 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31366853
Article Published Date : Jul 29, 2019
Study Type : In Vitro Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Laryngeal Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Combined oridonin with cetuximab treatment shows synergistic anticancer effects on laryngeal squamous cell carcinoma.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2016 Nov ;49(5):2075-2087. Epub 2016 Sep 19. PMID: 27667173
Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Laryngeal Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Natural Substance/Drug Synergy
[+]

Extracts from medicinal basidiomycetes mushrooms had anti-tumor activity against cancer cell lines. Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(11):955-964. PMID: 28008808
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom, Reishi Mushroom, Shiitake Mushroom
Diseases : Kidney Cancer, Laryngeal Cancer, Lung Cancer
Pharmacological Actions : Cytotoxic, Immunomodulatory
[+]

Farrerol suppresses the progression of laryngeal squamous cell carcinoma.Dec 14, 2021

Pubmed Data : Eur J Pharmacol. 2021 Dec 15 ;913:174636. Epub 2021 Nov 18. PMID: 34801529
Article Published Date : Dec 14, 2021
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Cancer Metastasis, Laryngeal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Fisetin had a potential role in controlling human laryngeal cancer through inhibiting tumor cell proliferation, inducing apoptosis and autophagy.Aug 19, 2016

Pubmed Data : Biomed Pharmacother. 2016 Aug 20 ;83:1164-1174. Epub 2016 Aug 20. PMID: 27551764
Article Published Date : Aug 19, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fisetin
Diseases : Laryngeal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation
[+]

Galangin suppresses human laryngeal carcinoma via modulation of caspase-3 and AKT signaling pathways.Jul 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Rep. 2017 Aug ;38(2):703-714. Epub 2017 Jun 29. PMID: 28677816
Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Laryngeal Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation, NF-kappaB Inhibitor
[+]

Luteolin inhibits angiogenesis and enhances radiotherapy sensitivity of laryngeal cancer.Oct 05, 2023

Pubmed Data : Tissue Cell. 2023 Oct 6 ;85:102235. Epub 2023 Oct 6. PMID: 37826960
Article Published Date : Oct 05, 2023
Study Type : In Vitro Study
Additional Links
Substances : Luteolin
Diseases : Laryngeal Cancer
Pharmacological Actions : Angiogenesis Inducing Agents, Radiosensitizer
[+]

Mechanisms underlying the cytotoxic effect of propolis on human laryngeal epidermoid carcinoma cells.Aug 07, 2017

Pubmed Data : Nat Prod Res. 2017 Aug 8:1-7. Epub 2017 Aug 8. PMID: 28783983
Article Published Date : Aug 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Bee Propolis
Diseases : Laryngeal Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation
[+]

Mi-RNA-888-5p is involved in S-adenosylmethionine antitumor effects in laryngeal squamous cancer cells.Dec 06, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2020 Dec 7 ;12(12). Epub 2020 Dec 7. PMID: 33297397
Article Published Date : Dec 06, 2020
Study Type : In Vitro Study
Additional Links
Substances : S-Adenosylmethionine (SAMe)
Diseases : Laryngeal Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, MicroRNA modulator
[+]

Noni has selective cytotoxicity against Laryngeal Cancer, Breast Cancer, and Neuroblastoma cell lines. Jun 01, 2006

Pubmed Data : Phytother Res. 2006 Jun;20(6):515-7. PMID: 16619339
Article Published Date : Jun 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Breast Cancer, Laryngeal Cancer, Neuroblastoma
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts, Selective Cytotoxicity
[+]

Pre-treatment with berberine enhances effect of 5-fluorouracil and cisplatin in HEP2 laryngeal cancer cell line.Dec 31, 2017

Pubmed Data : J Biol Regul Homeost Agents. 2018 Jan-Feb;32(2 Suppl. 1):167-177. PMID: 29460537
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Laryngeal Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemotherapeutic Synergy: Cisplatin
[+]

The effect of morusin on stemness phenotype of laryngeal cancer stem cell.Aug 31, 2020

Pubmed Data : Sichuan Da Xue Xue Bao Yi Xue Ban. 2020 Sep ;51(5):650-657. PMID: 32975079
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Mulberry
Diseases : Laryngeal Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Cancer Stem Cells
[+]

These findings suggest that genistein can suppress laryngeal cancer cell survival.Sep 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Oct ;106:665-671. Epub 2018 Jul 11. PMID: 29990856
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Genistein
Diseases : Laryngeal Cancer
Pharmacological Actions : Apoptotic, MicroRNA modulator, Tumor Suppressor Protein p53 Upregulation
[+]

Xanthohumol inhibits proliferation of laryngeal squamous cell carcinoma.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2016 Dec ;12(6):5289-5294. Epub 2016 Oct 25. PMID: 28105237
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Laryngeal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Zerumbone has antiproliferative effect and arrests cell cycle in laryngeal carcinoma cells in vitro.Jun 30, 2016

Pubmed Data : Nutr Cancer. 2016 Jul ;68(5):865-72. Epub 2016 Apr 4. PMID: 27045964
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Zerumbone
Diseases : Laryngeal Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest

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