Leukemia: Acute promyelocytic leukemia

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44 Substances Researched for Leukemia: Acute promyelocytic leukemia
NameACCKFocus
Indigo Naturalis211Locked
Vitamin C26Locked
Vitamin C: Intravenous 15Locked
Crocetin23Locked
Curcumin23Locked
Kaempferol33Locked
NAC (N-acetyl-L-cysteine)23Locked
Seaweed: Brown 13Locked
Tanshinone IIA23Locked
Cinnamon22Locked
EGCG (Epigallocatechin gallate)22Locked
Fucoidan12Locked
Ginseng (Siberian)12Locked
Ginsenosides22Locked
Myrtle12Locked
Polyphenols12Locked
Quercetin22Locked
Alpha-Lipoic Acid11Locked
Antrodia camphorata11Locked
Astragalus11Locked
Berberine11Locked
Cashew11Locked
Chaga Mushroom (Inonotus obliquus)11Locked
Cucurbitacin B 11Locked
Deguelin11Locked
Flavonoids11Locked
Fulvic Acid11Locked
Ginseng11Locked
Honokiol11Locked
Humic Acid11Locked
Long Pepper11Locked
Mululuza11Locked
Phloretin11Locked
Piperlongumine 11Locked
Puerarin11Locked
Purslane11Locked
Sesamin11Locked
Shallot11Locked
Shikonin11Locked
Sulforaphane11Locked
Thymoquinone11Locked
Toona sinensis 11Locked
Verbascoside11Locked
Vitamin E: alpha tocopherol11Locked
1 Problem Substances Researched for Leukemia: Acute promyelocytic leukemia
NameACCKFocus
Arsenic Trioxide23Locked
1 Therapeutic Actions Researched for Leukemia: Acute promyelocytic leukemia
NameACCKFocus
Light-Emitting Diodes (LEDs) Therapy11Locked
Related Topics

Leukemia: Acute promyelocytic leukemia is a Sub of the following Topic

View the Evidence:
50 Abstracts with Leukemia: Acute promyelocytic leukemia Research

[+]

Oral realgar-Indigo naturalis formula treatment for acute promyelocytic leukemia in children.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:8314176. Epub 2022 Jul 5. PMID: 35836830
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Indigo Naturalis
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Treatment with high extracellular concentrations of ascorbic acid alone directly induced cancer cell death.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Rep. 2017 Jan ;6(1):103-107. Epub 2016 Nov 29. PMID: 28123717
Article Published Date : Dec 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Vitamin C, Vitamin C: Intravenous
Diseases : Leukemia: Acute promyelocytic leukemia , Promyelocytic leukemia
Pharmacological Actions : Antioxidants, Apoptotic, Chemotherapeutic, Radioprotective
[+]

Anti-leukemia activity of polysaccharide from Sargassum fusiforme.May 07, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2023 May 8 ;21(5). Epub 2023 May 8. PMID: 37233483
Article Published Date : May 07, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Seaweed: Brown
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic
Additional Keywords : Polysaccharides
[+]

Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2020 Dec ;22(6):5271-5281. Epub 2020 Oct 14. PMID: 33173984
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Crocetin
Diseases : Arsenic Poisoning, Chemotherapy-Induced Toxicity: Arsenic Trioxide, Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Cardioprotective
Problem Substances : Arsenic Trioxide
[+]

Antileukemic, antioxidant, anti-inflammatory and healing activities induced by a polyphenol-enriched fraction extracted from leaves of myrtus.Nov 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Nov 27 ;14(23). Epub 2022 Nov 27. PMID: 36501085
Article Published Date : Nov 26, 2022
Study Type : Animal Study
Additional Links
Substances : Myrtle, Polyphenols
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemopreventive
Additional Keywords : Plant Extracts
[+]

Curcumin inhibits leukemia cells in mice. Jan 01, 2008

Pubmed Data : In Vivo. 2008 Jan-Feb;22(1):63-8. PMID: 18396784
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antineoplastic Agents
[+]

Fucoidan suppressed the proliferation and induced apoptosis through the intrinsic and extrinsic pathways in the acute promyelocytic leukemia (APL) cell lines NB4 and HL60Aug 02, 2015

Pubmed Data : J Cell Physiol. 2015 Aug 3. Epub 2015 Aug 3. PMID: 26241708
Article Published Date : Aug 02, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

N-acetyl-L-cysteine may have potential benefits in terms of elevating antioxidant activity and preventing leukemia initiation.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Aug ;16(2):2046-2052. Epub 2018 May 31. PMID: 30008899
Article Published Date : Jul 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Leukemia, Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

Phytochemical content and pharma-nutrition study on Eleutherococcus senticosus fruits intractum.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:9270691. Epub 2016 Oct 24. PMID: 27843534
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Ginseng (Siberian)
Diseases : Leukemia: Acute promyelocytic leukemia , Multiple Myeloma
Pharmacological Actions : Antioxidants, Antiproliferative , Chemotherapeutic
Additional Keywords : Plant Extracts
[+]

Tanshinone IIA inhibits acute promyelocytic leukemia cell proliferation and induces their apoptosis in vivo.Dec 31, 2015

Pubmed Data : Blood Cells Mol Dis. 2016 Jan ;56(1):46-52. Epub 2015 Oct 27. PMID: 26603724
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

20( S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia.Feb 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2021 Mar ;45(2):295-304. Epub 2020 May 15. PMID: 33841010
Article Published Date : Feb 28, 2021
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic
[+]

20(S)-ginsenoside Rh2 ameliorates ATRA resistance in acute promyelocytic leukemia.Apr 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2024 May ;48(3):298-309. Epub 2023 Dec 27. PMID: 38707638
Article Published Date : Apr 30, 2024
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Chemosensitizer
[+]

280 nm UV LED irradiation inhibits proliferation and induces apoptosis and necrosis in cultured HL-60 human leukemia cells.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2016 Mar ;13(3):2506-10. Epub 2016 Jan 27. PMID: 26820261
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Leukemia: Acute promyelocytic leukemia
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest
Additional Keywords : Dose Response
[+]

A novel realgar-indigo naturalis formula more effectively induces apoptosis in NB4 cells.Apr 30, 2019

Pubmed Data : Pak J Pharm Sci. 2019 May ;32(3):957-962. PMID: 31278706
Article Published Date : Apr 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Indigo Naturalis
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Acteoside inhibits human promyelocytic HL-60 leukemia cell proliferation.Aug 31, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Carcinogenesis. 2007 Sep ;28(9):1928-36. Epub 2007 Jul 18. PMID: 17634406
Article Published Date : Aug 31, 2007
Study Type : In Vitro Study
Additional Links
Substances : Verbascoside
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Cell cycle arrest, P21 Activation
[+]

Anti-proliferative profile of Anacardium occidentale polysaccharide.Jul 31, 2020

Pubmed Data : Int J Biol Macromol. 2020 Aug 1 ;156:981-987. Epub 2020 Mar 16. PMID: 32194125
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cashew
Diseases : Colorectal Cancer, Leukemia: Acute promyelocytic leukemia , Melanoma
Pharmacological Actions : Antiproliferative
Additional Keywords : Polysaccharides, Selective Antiproliferation
[+]

Anticancer and anti-inflammatory activities of shallot extract.Jan 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Med Sci. 2011 Feb ;7(1):38-44. Epub 2011 Mar 8. PMID: 22291731
Article Published Date : Jan 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Shallot
Diseases : Breast Cancer, Cervical Cancer, Inflammation, Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative
Additional Keywords : Plant Extracts
[+]

Apoptosis of NB4 cells was induced by puerarin in vitro.Mar 31, 2010

Pubmed Data : Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Apr ;18(2):326-9. PMID: 20416161
Article Published Date : Mar 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Apoptosis-inducing effect of quercetin and kaempferol on human HL-60 cells and its mechanism.May 31, 2010

Pubmed Data : Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Jun ;18(3):629-33. PMID: 20561416
Article Published Date : May 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol, Quercetin
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Astragalus membranaceus saponins can be used in the treatment of inflammatory diseases and inflammation-mediated tumor development.Apr 23, 2016

Pubmed Data : Am J Chin Med. 2016 Apr 24:1-15. Epub 2016 Apr 24. PMID: 27109155
Article Published Date : Apr 23, 2016
Study Type : In Vitro Study
Additional Links
Substances : Astragalus
Diseases : Leukemia, Leukemia: Acute promyelocytic leukemia , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Antioxidants, Chemoprotective Agents, Immunomodulatory
[+]

Berberine induces apoptotic cell death in HL-60 human leukemia cells.Dec 31, 2016

Pubmed Data : Am J Chin Med. 2017 ;45(7):1497-1511. PMID: 29025293
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Cinnamon extract inhibit the tumor cell survival by both down-regulated their target cell cycle regulation molecules and mitosis regulation molecules.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2018 08 ;22(16):5347-5354. PMID: 30178861
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon
Diseases : Cervical Cancer, Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts
[+]

Cucurbitacin B synergistically enhances the apoptosis-inducing effect of arsenic trioxide by inhibiting STAT3 phosphorylation in Ramos cells.Feb 19, 2017

Pubmed Data : Leuk Lymphoma. 2017 Feb 20:1-13. Epub 2017 Feb 20. PMID: 28278714
Article Published Date : Feb 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic
Problem Substances : Arsenic Trioxide
[+]

Curcumin induces programmed cell death in human promyelocytic leukemia HL-60 cells.Feb 13, 2008

Pubmed Data : Life Sci. 2008 Feb 13;82(7-8):367-75. Epub 2007 Dec 7. PMID: 18187158
Article Published Date : Feb 13, 2008
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Apoptotic
[+]

Deguelin blocks cells survival signal pathways and induces apoptosis of HL-60 cells in vitro.May 31, 2009

Pubmed Data : Int J Hematol. 2009 Jun ;89(5):618-23. Epub 2009 May 20. PMID: 19455392
Article Published Date : May 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Deguelin
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antineoplastic Agents, Apoptotic
[+]

Epigallocatechin-3-gallate induces apoptosis in acute promyelocytic leukemia cells.Oct 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Nov ;14(5):6314-6320. Epub 2017 Sep 18. PMID: 29113283
Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic
[+]

Extracts of Toona sinensis and fermented culture broths of Antrodia camphorata synergistically cause apoptotic cell death in promyelocytic leukemia cells. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2020 Jan-Dec;19:1534735420923734. PMID: 32618215
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata, Toona sinensis
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Natural Substance Synergy
[+]

Fulvic acid most likely stimulates immune-modulating molecules such as NO and induces cancer cell apoptosis.Jun 30, 2016

Pubmed Data : Int Immunopharmacol. 2016 Jul ;36:241-8. Epub 2016 May 11. PMID: 27177083
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fulvic Acid
Diseases : Fibrosarcoma, Leukemia: Acute promyelocytic leukemia , Liver Cancer, Prostate Cancer
Pharmacological Actions : Apoptotic, Nitric Oxide Enhancer
[+]

Green tea polyphenol EGCG causes anti-cancerous epigenetic modulations in acute promyelocytic leukemia cells.Jun 21, 2017

Pubmed Data : Leuk Lymphoma. 2017 Jun 22:1-10. Epub 2017 Jun 22. PMID: 28641467
Article Published Date : Jun 21, 2017
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Chemotherapeutic
Additional Keywords : Epigenetic Modification In Cancer
[+]

Hesperetin promoted cell death in the human leukemic cell line U937.Feb 12, 2023

Pubmed Data : Curr Issues Mol Biol. 2023 Feb 13 ;45(2):1587-1600. Epub 2023 Feb 13. PMID: 36826047
Article Published Date : Feb 12, 2023
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Acute Myeloid Leukemia, Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic
[+]

Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Apoptosis. 2021 Apr ;26(3-4):195-208. Epub 2021 Feb 7. PMID: 33550458
Article Published Date : Mar 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Paraptosis
[+]

Humic acid induces apoptosis in human premyelocytic leukemia HL-60 cells.Aug 27, 2004

Pubmed Data : Life Sci. 2004 Aug 27;75(15):1817-31. PMID: 15302226
Article Published Date : Aug 27, 2004
Study Type : In Vitro Study
Additional Links
Substances : Humic Acid
Diseases : Leukemia: Acute promyelocytic leukemia , Promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Induction of apoptosis in human promyelocytic leukemia HL60 cells by panaxynol and panaxydol.Jun 28, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2011 Jun 29 ;16(7):5561-73. Epub 2011 Jun 29. PMID: 21716177
Article Published Date : Jun 28, 2011
Study Type : In Vitro Study
Additional Links
Substances : Ginseng
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Kaempferol increases apoptosis in human acute promyelocytic leukemia cells and inhibits multidrug resistance genes.Sep 01, 2017

Pubmed Data : J Cell Biochem. 2017 Sep 2. Epub 2017 Sep 2. PMID: 28865123
Article Published Date : Sep 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic, Multidrug Resistance Gene Modulators
[+]

kaempferol induced DNA damage and suppressed DNA repair and inhibited DNA repair associated protein expression in HL-60 cellsDec 31, 2014

Pubmed Data : Am J Chin Med. 2015 ;43(2):365-82. Epub 2015 Mar 17. PMID: 25779644
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Cytotoxicity, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Dose Response
[+]

L-ascorbic acid and α-tocopherol synergistically triggers apoptosis inducing antileukemic effects of arsenic trioxide.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2020 ;10:65. Epub 2020 Feb 21. PMID: 32154163
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C, Vitamin E: alpha tocopherol
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Natural Substance Synergy
[+]

N-acetylcysteine can induce massive oxidative stress, resulting in cell death with apoptotic features in human leukemia cells.Nov 22, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Nov 23 ;22(23). Epub 2021 Nov 23. PMID: 34884437
Article Published Date : Nov 22, 2021
Study Type : In Vitro Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Phenolic compounds from chaga mushrooms have cytotoxicity against cancer cells. May 31, 2009

Pubmed Data : J Med Food. 2009 Jun ;12(3):501-7. PMID: 19627197
Article Published Date : May 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus)
Diseases : Cancers: All, Carcinoma: Non-Small-Cell Lung, Leukemia: Acute promyelocytic leukemia , Lymphoma, Ovarian Cancer
Pharmacological Actions : Antineoplastic Agents, Antioxidants, Apoptotic, Cytotoxic
Additional Keywords : Plant Extracts, Selective Cytotoxicity
[+]

Phloretin-induced apoptosis in B16 melanoma 4A5 cells and HL60 human leukemia cells.Mar 31, 1999

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 1999 Apr ;63(4):719-25. PMID: 10361685
Article Published Date : Mar 31, 1999
Study Type : In Vitro Study
Additional Links
Substances : Phloretin
Diseases : Leukemia: Acute promyelocytic leukemia , Melanoma
Pharmacological Actions : Apoptotic
[+]

Piperlongumine and alpha lipoic acid may have a potential value as a therapeutic agent for patients with acute promyelocytic leukemia.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer Res Ther. 2016 Apr-Jun;12(2):556-60. PMID: 27461609
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Alpha-Lipoic Acid, Long Pepper, Piperlongumine
Diseases : Leukemia, Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Chemotherapeutic, Cyclooxygenase 2 Inhibitors
Additional Keywords : Natural Substance Synergy
[+]

Portulacerebroside A can act as a new agent for leucocythemia treatment.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Pathol. 2015 ;8(11):13968-77. Epub 2015 Nov 1. PMID: 26823708
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Purslane
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Sesamin acts as anti-leukemic compound.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Cell Med. 2022 ;11(1):1-15. Epub 2022 Oct 4. PMID: 36397810
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Sesamin
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic
[+]

Shikonin suppresses proliferation and induces apoptosis in human leukemia NB4 cells.Aug 31, 2017

Pubmed Data : Mol Med Rep. 2017 Sep ;16(3):3055-3060. Epub 2017 Jul 13. PMID: 28713949
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Dose Response
[+]

Study of the mechanisms of crocetin-induced differentiation and apoptosis in human acute promyelocytic leukemia cells.Sep 10, 2018

Pubmed Data : J Cell Biochem. 2018 Sep 11. Epub 2018 Sep 11. PMID: 30203596
Article Published Date : Sep 10, 2018
Study Type : In Vitro Study
Additional Links
Substances : Crocetin
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic
[+]

Sulforaphane induces differentiation in human promyelocytic cells, indicating it may be a promising antileukemic agent.Aug 01, 2004

Pubmed Data : Platelets. 2004 Aug;15(5):287-92. PMID: 18610742
Article Published Date : Aug 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Leukemia: Acute promyelocytic leukemia , Promyelocytic leukemia
Pharmacological Actions : Cell Differentiation Inducer
Additional Keywords : Isothiocyanates
[+]

Supplemented C. zeylanicum aqueous extract induced apoptosis in the human myelocytic leukemia cell line (THP-1).Dec 31, 2014

Pubmed Data : Bratisl Lek Listy. 2015 ;116(2):132-5. PMID: 25665482
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts
[+]

The combination of nutlin-3 and tanshinone IIA promotes synergistic cytotoxicity in acute leukemic cells.Dec 31, 2018

Pubmed Data : Int J Biochem Cell Biol. 2019 01 ;106:8-20. Epub 2018 Oct 30. PMID: 30389549
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Natural Substance/Drug Synergy
[+]

The combination of quercetin and Adriamycin effectively suppresses the growth of refractory acute leukemia.Jun 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2019 Jul ;18(1):153-160. Epub 2019 May 2. PMID: 31289484
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Acute lymphoblastic leukemia (ALL), Leukemia, Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Antiproliferative
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin
[+]

Thymoquinone is a booster for the anti-cancer effect of doxorubicin in certain cancer cell lines.Mar 31, 2011

Pubmed Data : Cancer Chemother Pharmacol. 2011 Apr ;67(4):867-74. Epub 2010 Jun 26. PMID: 20582416
Article Published Date : Mar 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Breast Cancer, Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin
[+]

Vernonia amygdalina induced apoptosis in treated cells compared to the control cells.Jul 31, 2018

Pubmed Data : Glob J Adv Eng Technol Sci. 2018 Aug ;5(8):1-9. Epub 2018 Aug 10. PMID: 30310827
Article Published Date : Jul 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Mululuza
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Apoptotic
Additional Keywords : Baganda Traditional Medicine

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