Lipopolysaccharide-Induced Toxicity

Name	AC	CK
Curcumin	43	59
Ginsenosides	27	39
Flavonoids	14	28
Vitamin C	9	25
Polyphenols	9	24
Resveratrol	16	23
DHA (Docosahexaenoic Acid)	3	22
Pomegranate	2	20
Dandelion	14	17
Tanshinone IIA	11	15
Fermented Foods and Beverages	3	14
Honokiol	3	14
Isoflavones	3	14
Probiotics	3	14
Puerarin	9	13
Strawberry	4	13
Melatonin	5	12
Berberine	7	11
Vitamin D	2	11
Bacillus coagulans	1	10
Bilberry	1	10
Lactobacillus Acidophilus	1	10
Myricetin	7	10
Stilbenes	7	10
Yoghurt	1	10
Asiatic Acid	7	9
Cannabidiol	6	9
Echinacea	3	9
Fucoidan	7	9
Ginger	5	9
Luteolin	6	9
Punicalagin	5	9
Sesamol	5	9
Sulforaphane	7	9
Thymoquinone	5	9
Astragaloside	5	8
Genipin	6	8
Astaxanthin	4	7
Citrus naringin	4	7
Rose	4	7
Rutin	4	7
Thymol	4	7
Verbascoside	5	7
Barley	3	6
Bifidobacterium Longum	3	6
Cannabis	4	6
EGCG (Epigallocatechin gallate)	5	6
Fisetin	4	6
Green Tea	3	6
Hops	3	6
Nigella sativa (aka Black Seed)	3	6
Paeoniflorin	4	6
Piperine	4	6
Shikonin	4	6
Zerumbone	3	6
Caffeic acid phenethyl ester	1	5
Cannabinoids	4	5
Citral	1	5
Delta-tetrahydrocannabinol (THC)	4	5
Hydroxytyrosol	3	5
Licorice	3	5
Lotus	5	5
Mulberry	3	5
Naringenin	3	5
Nobiletin	3	5
Panax Notoginseng	3	5
Parthenolide	4	5
Piceatannol	4	5
Quercetin	4	5
Red Sage	3	5
Silibinin	3	5
Adlay	4	4
Bay leaf	3	4
Blue Honeysuckle	2	4
Chrysanthemum Indicum	3	4
Diosgenin	2	4
False Black Pepper	2	4
Ferulic acid	2	4
Garlic	2	4
Gastrodin	3	4
Geraniol	2	4
Ginseng (Siberian)	2	4
Huperzine	2	4
Isoliquiritigenin	2	4
Japanese cypress	2	4
Lactobacillus helveticus	2	4
Lactobacillus plantarum	2	4
Lupeol	2	4
Lycopene	2	4
Mangiferin	3	4
Mangosteen	3	4
Mussel: Green-lipped (Perna canaliculus)	2	4
Pine Needle	3	4
Pterostilbene	3	4
Purslane	2	4
Rosemaric Acid	2	4
Sesamin	2	4
Soy	2	4
Toona sinensis	3	4
Vitexins	3	4
Agrimony	2	3
Allicin	2	3
Anthocyanins	2	3
Apigenin	3	3
Ashwagandha	2	3
Bee Venom	3	3
Celery	2	3
Chrysin	3	3
Cinnamaldehyde	2	3
Coenzyme Q10	2	3
Flaxseed	2	3
Fucoxanthin	2	3
Gingerol	2	3
Ginkgo biloba	2	3
Hemp Seed	2	3
Hesperidin	2	3
Krill	2	3
Loquat Leaves	3	3
Neem	2	3
Phloretin	2	3
Prickly Pear Cactus	3	3
Salvia miltiorrhiza	2	3
Sea buckthorn	2	3
Spikenard	3	3
Tangeretin	2	3
Turmeric	3	3
Ubiquinol	3	3
Vanillin	3	3
Xanthohumol	2	3
Acai	1	2
Acorus calamus	1	2
Aduki bean	1	2
African Basil	1	2
Aloe Vera	1	2
Amygdalin	1	2
Arctigenin	1	2
Arginine	1	2
Bael	1	2
Bai Zhu	2	2
Belladonna	1	2
Beta-glucan	1	2
Bisdemethoxycurcumin	1	2
Black Pepper	1	2
Black Tea	1	2
Blueberry	2	2
Bromelain	2	2
Buckwheat	1	2
Capparis spinosa (caper)	1	2
Centella asiatica	1	2
Cocoa	2	2
Coffee	1	2
Cordyceps sinensis	1	2
Corn Silk	1	2
Curry Leaves	1	2
Damnacanthal	1	2
Diallyl sulfide	1	2
Ellagic Acid	1	2
Emodin	1	2
Fish Oil	1	2
Flaxseed Oil	1	2
Garden Cress (Lepidium sativum)	1	2
Gardenia	1	2
Genistein	2	2
Glucosamine	1	2
Gotu Kola	2	2
Grape Seed Extract	1	2
Hibiscus sabdariffa	1	2
Histidine	1	2
Honey	1	2
Hydrogen Water	1	2
Indole-3-Carbinol	1	2
Isoquercitrin	1	2
Justicia gendarussa	2	2
Lactobacillus casei	1	2
Lactobacillus gasseri	1	2
Lactobacillus reuteri	1	2
Lithium	1	2
MSM (Methylsulfonylmethane)	2	2
Magnesium Sulfate	1	2
Manuka Honey	2	2
Modified Citrus Pectin	1	2
Mushrooms: All	2	2
Noni	1	2
P-Coumaric Acid	1	2
Palmitoylethanolamide	1	2
Patchouli	1	2
Perillaldehyde	1	2
Phyllanthus amarus	2	2
Pine Bark Extract	1	2
Pine Cone	2	2
Piperlongumine	1	2
Polyunsaturated Fatty Acids (PUFAs)	1	2
Potato	1	2
Propolis: Brazillian	1	2
Pycnogenol (Pine Bark)	2	2
Radish	1	2
Raspberry	1	2
Reishi Mushroom	2	2
Riboflavin (Vitamin B-2)	1	2
Rosemary	2	2
Rosmarinic acid	1	2
Saffron	1	2
Sage	1	2
Saw Palmetto	1	2
Selenium	1	2
Spirulina	1	2
Sprouts	1	2
Stevia	1	2
Stigmasterol	1	2
Sweet Potato: Purple	1	2
Thuja	1	2
Turmerones	1	2
Vitamin B-12	1	2
Vitamin B-12: Hydroxocobalamin	1	2
Whey	1	2
Zataria multiflora	1	2
6-Shogaol	1	1
Acacia catechu	1	1
Amygdalin (laetrile)	1	1
Andrographis	1	1
Antrodia camphorata	1	1
Apocynin	1	1
Apple Pectin	1	1
Artesunate	1	1
Astragalus	1	1
Ayahuasca	1	1
Baicalein	1	1
Barley Grass	1	1
Bee Propolis	1	1
Benzyl isothiocyanate	1	1
Beta Sitosterol	1	1
Beta-Caryophyllene	1	1
Beta-Elemene	1	1
Black Raspberry	1	1
Boron	1	1
Butterbur	1	1
Carnosic Acid	1	1
Catechin	1	1
Catechols	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Chamomile	1	1
Cherry: All Varieties	1	1
Chicoric Acid	1	1
Cordyceps Militaris	1	1
Cryptoxanthin	1	1
Cucurbitacin B	1	1
Cucurbitacin E	1	1
Curcumin: Degradiation byproducts	1	1
Curcumin: Lipidated	1	1
Diosmin	1	1
Eucalyptus	1	1
Euphorbia peplus	1	1
False Daisy	1	1
Flowers	1	1
Frankincense	1	1
Garlic: Aged	1	1
Guggul	1	1
Horseradish	1	1
Hyaluronic Acid	1	1
Jujube	1	1
Juniper	1	1
Knema laurina	1	1
Kombucha Tea	1	1
Lactobacillus rhamnosus	1	1
Lactobacillus rhamnosus GG	1	1
Lauric acid	1	1
Lavender: Essential Oil	1	1
Lignans	1	1
Ligustrazine	1	1
Lion's Mane (Hericium Erinaceus)	1	1
Longan	1	1
Maple Syrup	1	1
Matairesinol	1	1
Medicinal Mushrooms	1	1
Methionine	1	1
Moringa oleifera	1	1
Oak	1	1
Panax Ginseng	1	1
Passion Flower	1	1
Peppermint	1	1
Perilla	1	1
Persimmon	1	1
Phenethyl isothiocyanate	1	1
Plantago	1	1
Polyacetylenes	1	1
Pomegranate Peel	1	1
Pomegranate flower	1	1
Prebiotics	1	1
Prunella vulgaris	1	1
Purple Carrots	1	1
Red Cabbage	1	1
Red Clover	1	1
Rhubarb	1	1
Rice: Black	1	1
Royal Jelly	1	1
Saccharomyces Boulardii	1	1
Seaweed: Brown	1	1
Sessile Joyweed	1	1
Sour Cherry	1	1
Syrian rue	1	1
Tea	1	1
Thistle	1	1
Thyme	1	1
Tualang Honey	1	1
Urolithin A	1	1
Vitamin E: Gamma-tocotrienol	1	1
Vitex negundo	1	1
Willow Bark	1	1
Xanthones	1	1

Name	AC	CK
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	3	3
Aluminum	1	2
Antibiotics	1	2
Aspirin	1	2
Chlorpyrifos	1	2
Fluoxetine (trade name Prozac)	1	2
Oseltamivir (trade name Tamiflu)	1	2
Pesticides	1	2
Selective Serotonin Reuptake Inhibitors (SSRIs)	1	2
Ibuprofen	1	1

Name	AC	CK
Exercise	1	10
Exercise: Running	1	10
Homeopathic Treatment	1	2
Microbiota Transfer Therapy	1	2
Ultrasound therapy	1	2
Fasting/Caloric Restriction	1	1

Name	AC	CK	Focus
Western Diet	1	2

Additional Keywords : Microbiota

[+]

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID: 25948780

Article Published Date : Jun 30, 2015

Study Type : Human Study

Additional Links

Substances : Bacillus coagulans

Diseases : C-Reactive Protein, Dysbiosis, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Microbiota

[+]

DHA diet supplementation attenuated cytokine production after exercise.Aug 31, 2016

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Pubmed Data : J Physiol Biochem. 2016 Sep ;72(3):421-34. Epub 2016 May 2. PMID: 27139422

Article Published Date : Aug 31, 2016

Study Type : Human Study

Additional Links

Substances : DHA (Docosahexaenoic Acid)

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents

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Additional Keywords : Plant Extracts

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There is a measurable systemic inflammatory response in first trimester pregnancy failure.Jan 31, 2012

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Pubmed Data : Hum Reprod. 2012 Feb ;27(2):349-57. Epub 2011 Nov 29. PMID: 22131390

Article Published Date : Jan 31, 2012

Study Type : Human Study

Additional Links

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Miscarriage

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mediators Inflamm. 2014 ;2014:426740. Epub 2014 Aug 1. PMID: 25253919

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress, Pneumonia

Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Vitamin D partially reversed the effect of lipopolysaccharide induced imbalances and protected patients with T2DM and DNU.Aug 28, 2016

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Pubmed Data : Genet Mol Res. 2016 Aug 29 ;15(3). Epub 2016 Aug 29. PMID: 27706649

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Pubmed Data : Inflammation. 2015 Dec 11. Epub 2015 Dec 11. PMID: 26658749

Article Published Date : Dec 10, 2015

Study Type : Human In Vitro

Additional Links

Substances : Citral

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Elderberry and elderflower extracts inhibit nitric oxide production in lipopolysaccharide-activated macrophages.Mar 08, 2017

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Pubmed Data : Int J Mol Sci. 2017 Mar 8 ;18(3). Epub 2017 Mar 8. PMID: 28282861

Article Published Date : Mar 08, 2017

Study Type : Human In Vitro

Additional Links

Substances : Elderberry

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Immunomodulatory

Additional Keywords : Plant Extracts

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Hydrocortisone and ascorbic acid synergistically prevent and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunction.Jan 10, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Poult Sci. 2020 Jul ;99(7):3411-3427. Epub 2020 Apr 15. PMID: 32616235

Article Published Date : Jun 30, 2020

Study Type : Animal Study

Additional Links

Substances : Genistein

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Gastrointestinal Agents, Gastroprotective

[+]

Effects of Oridonin on growth performance and oxidative stress in broilers challenged with lipopolysaccharide.Sep 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2019 May 28 ;24(11). Epub 2019 May 28. PMID: 31141940

Article Published Date : May 27, 2019

Study Type : Animal Study

Additional Links

Substances : Honokiol

Diseases : Depression, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Antidepressant-like effects of β-caryophyllene on restraint plus stress-induced depression.Feb 16, 2020

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Pubmed Data : Behav Brain Res. 2020 Feb 17 ;380:112439. Epub 2019 Dec 17. PMID: 31862467

[+]

Astaxanthin ameliorates the behavioural deficits of prenatal maternal LPS-exposure.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Neurosci. 2016 ;17(1):11. Epub 2016 Feb 8. PMID: 26856812

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress, Prenatal Chemical Exposures

Pharmacological Actions : Antioxidants

[+]

Astaxanthin ameliorates the lipopolysaccharides-induced subfertility.Jun 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Kaohsiung J Med Sci. 2020 Oct 22. Epub 2020 Oct 22. PMID: 33089927

Article Published Date : Oct 21, 2020

Study Type : Animal Study

Additional Links

Substances : Astragaloside

Diseases : Lipopolysaccharide-Induced Toxicity, Pre-Eclampsia

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor

[+]

Astragaloside IV protects rat gastric mucosa against aspirin-induced damage.Nov 30, 2016

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Pubmed Data : Int Immunopharmacol. 2016 Dec ;41:47-55. Epub 2016 Nov 2. PMID: 27816726

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2016 Jul 21 ;8(7). Epub 2016 Jul 21. PMID: 27455313

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Pubmed Data : Food Funct. 2019 May 7. Epub 2019 May 7. PMID: 31062778

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Carnosic acid protects against lipopolysaccharide-induced acute lung injury in mice.Oct 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2019 Nov ;18(5):3707-3714. Epub 2019 Sep 23. PMID: 31611929

Article Published Date : Oct 31, 2019

Study Type : Animal Study

Additional Links

Substances : Carnosic Acid

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Carvacrol has significant potential as an inhibitor of memory degeneration in neurodegenerative diseases.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:320136. Epub 2015 Sep 17. PMID: 26457108

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Strawberry

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2020 Aug ;45(16):3938-3944. PMID: 32893592

Article Published Date : Jul 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Honeysuckle

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Constituents of Moringa oleifera seeds regulate expression of Th17-relevant cytokines and ameliorate TPA-induced psoriasis-like skin lesions.Dec 09, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2018 Dec 10 ;23(12). Epub 2018 Dec 10. PMID: 30544700

Article Published Date : Dec 09, 2018

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Pubmed Data : J Agric Food Chem. 2017 Feb 1 ;65(4):759-768. Epub 2017 Jan 17. PMID: 28064493

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Corn Silk

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Crocetin may be used as a novel therapy for preventing fulminant hepatic failure.Oct 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Inflammopharmacology. 2017 Mar 13. Epub 2017 Mar 13. PMID: 28289922

Article Published Date : Mar 12, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Endotoxemia, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin alleviated lung edema in lipopolysaccharide induced acute lung injury by inhibiting inflammation.Feb 25, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Echinacea reduces Candida albicans associated mortality in mice.Jan 01, 2006

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Pubmed Data : J Cardiovasc Pharmacol. 2006;47 Suppl 2:S177-86; discussion S206-9. PMID: 15949903

Emodin alleviated LPS-induced pulmonary inflammation in rat lung tissues.Mar 31, 2020

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Pubmed Data : Inflamm Res. 2020 Apr ;69(4):365-373. Epub 2020 Mar 4. PMID: 32130427

Article Published Date : Mar 31, 2020

Study Type : Animal Study

Additional Links

Substances : Emodin

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Emodin showed excellent hepatoprotective effects against lipopolysaccharide-induced acute liver injury.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Zhonghua Yi Xue Za Zhi. 2019 May 28 ;99(20):1582-1587. PMID: 31154727

Article Published Date : May 27, 2019

Study Type : Animal Study

Additional Links

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Therapeutic Actions : Microbiota Transfer Therapy

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Fermented barley extract effectively inhibited the propagation of inflammation by suppressing oxidative stress.Dec 31, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biosci Biotechnol Biochem. 2011 ;75(10):1971-6. Epub 2011 Oct 7. PMID: 21979071

Click here to read the entire abstract

Pubmed Data : Mol Neurobiol. 2019 Dec 12. Epub 2019 Dec 12. PMID: 31832973

Article Published Date : Dec 11, 2019

Study Type : Animal Study

Additional Links

Substances : Gallic Acid

Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Garden cress extracts have significant hepatoprotective activity in animals. Dec 02, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2016 Dec 3 ;16(1):501. Epub 2016 Dec 3. PMID: 27912738

Ginsenoside Rb1 protects dopaminergic neurons from inflammatory injury induced by intranigral lipopolysaccharide injection.Sep 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int Immunopharmacol. 2016 May ;34:53-59. Epub 2016 Feb 24. PMID: 26921732

Article Published Date : Apr 30, 2016

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Ginsenoside Rg3 attenuates lipopolysaccharide-induced acute lung injury.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2018 ;9:850. Epub 2018 Aug 2. PMID: 30116194

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Ginsenoside Rg3 attenuates microglia activation following systemic lipopolysaccharide treatment in mice.Dec 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2012 ;35(9):1546-52. PMID: 22975507

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Ginsenoside Rg3 was effective in ameliorating depressive-like behavior induced by immune activation.Aug 15, 2017

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Pubmed Data : J Agric Food Chem. 2017 Aug 16 ;65(32):6861-6869. Epub 2017 Aug 7. PMID: 28762741

Article Published Date : Aug 15, 2017

[+]

Green mussel extract decreases the production of cytokines associated with inflammation.Dec 01, 2008

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Pubmed Data : Eur Ann Allergy Clin Immunol. 2008 Dec;40(4):148-53. PMID: 19227651

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mar Drugs. 2019 Jun 17 ;17(6). Epub 2019 Jun 17. PMID: 31213027

Article Published Date : Jun 16, 2019

Study Type : Animal Study

Additional Links

Substances : Red Marine Algae

Diseases : Endotoxemia, Inflammation, Lipopolysaccharide-Induced Toxicity, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, STAT3 Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Homeopathic dilutions of Belladonna and Echinacea have therapeutic value in the treatment of experimental peritonitis.Oct 01, 2004

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Pubmed Data : Homeopathy. 2004 Oct;93(4):193-8. PMID: 15532698

Pubmed Data : J Med Food. 2018 Oct ;21(10):1009-1015. PMID: 30334699

Article Published Date : Sep 30, 2018

Study Type : Animal Study

Additional Links

Substances : Hops

Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Hepatoprotective, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Humulus japonicus inhibits the progression of Alzheimer's disease.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Med. 2017 Jan ;39(1):21-30. Epub 2016 Nov 16. PMID: 28004107

Article Published Date : Dec 31, 2016

Study Type : Transgenic Animal Study

Additional Links

Substances : Hops

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

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Huperzine A inhibits CCL2 production in experimental autoimmune encephalomyelitis.Jun 30, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Immunopathol Pharmacol. 2013 Jul-Sep;26(3):757-64. PMID: 24067473

Article Published Date : Jun 30, 2013

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Huperzine

Diseases : Lipopolysaccharide-Induced Toxicity, Multiple Sclerosis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Hydroxysafflor yellow A alleviates myocardial ischemia/reperfusion in hyperlipidemia.Jan 11, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Isogarcinol is a promising immunosuppressive agent for treating psoriasis.Jan 31, 2017

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Pubmed Data : J Agric Food Chem. 2017 Feb 1 ;65(4):846-857. Epub 2017 Jan 24. PMID: 28081600

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Mangosteen

Diseases : Lipopolysaccharide-Induced Toxicity, Psoriasis

Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-23 Downregulation, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Isoliquiritigenin attenuates adipose tissue inflammation in vitro and adipose tissue fibrosis.Mar 14, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2016 Mar 15 ;6:23097. Epub 2016 Mar 15. PMID: 26975571

Article Published Date : Mar 14, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Isoliquiritigenin

Diseases : Inflammation,

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View the Evidence: 1070 Abstracts with Lipopolysaccharide-Induced Toxicity Research

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Bilberry has anti-inflammatory properties.Sep 01, 2010

Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.Dec 06, 2006

Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia.May 16, 2018

Consumption of pomegranate extract decreased endotoxemia in overweight-obese individuals by reshaping the gut microbiota.May 31, 2018

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

DHA diet supplementation attenuated cytokine production after exercise.Aug 31, 2016

Extra virgin olive oil mitigates postprandial lipopolysaccharide-induced inflammation and oxidative stress.Mar 01, 2019

Honokiol protects pulmonary microvascular endothelial barrier against lipopolysaccharide-induced ARDS.Sep 30, 2018

Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.Feb 27, 2016

Lithium can increase brain 17-hydroxy-DHA formation, indicating a new and potentially important therapeutic action of lithium.May 01, 2010

Moderate running exercise prevents excessive immune system activation.Feb 18, 2019

Preeclampsia patients had gut microbiota dysbiosis and increased plasma lipopolysaccharide and trimethylamine-N-oxide levels.Dec 31, 2018

Probiotic administration in the elderly normalises the response to endotoxin, and modulates activation markers in blood phagocytes, and therefore may help reduce low-grade chronic inflammation.Jan 01, 2009

Puerarin acts as an anti-inflammatory agent by blocking NF-kappaB signalling.Jul 31, 2010

There is a measurable systemic inflammatory response in first trimester pregnancy failure.Jan 31, 2012

Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.Dec 31, 2013

Vitamin D partially reversed the effect of lipopolysaccharide induced imbalances and protected patients with T2DM and DNU.Aug 28, 2016

50 Hz magnetic fields and lipopolysaccharides synergistically reduce cell viability in vitro.Jan 10, 2016

Alpha-bisobolol inhibits lipopolysaccharide-induced inflammation.Oct 01, 2011

Caffeic acid phenethyl ester could be effective for treating of periodontal diseases.Nov 06, 2016

Citral inhibits LPS-induced inflammatory response via activating PPAR-γ which attenuates NF-κB activation.Dec 10, 2015

Elderberry and elderflower extracts inhibit nitric oxide production in lipopolysaccharide-activated macrophages.Mar 08, 2017

Hydrocortisone and ascorbic acid synergistically prevent and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunction.Jan 10, 2017

Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.Aug 31, 2012

Oleocanthal inhibits catabolic and inflammatory mediators in LPS-activated human primary osteoarthritis chondrocytes.Dec 31, 2017

Plant polyphenols mitigate the pro-inflammatory and pro-oxidant adipocyte response to lipopolysaccharides.Jan 01, 2017

Resveratrol could be a prime candidate in ameliorating dysfunctioning adipose tissue induced by inflammatory stimulation.Jan 01, 2016

Strawberry extracts efficiently counteract inflammatory stress induced by the endotoxin lipopolysaccharide.Feb 15, 2018

T. cordifolia dry leaf extracts possess antioxidant and anti-inflammatory properties.Jul 31, 2019

These results showed for the first time a clear and a dose-dependent protective effect of strawberry extract on LPS-induced damage in HDF cell line.Jan 20, 2017

α-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.Jan 01, 2014

Aloin suppresses lipopolysaccharide-induced acute lung injury by inhibiting NLRP3/NF-κB via activation of SIRT1 in mice.Jul 31, 2020

Dietary genistein supplementation protects against lipopolysaccharide-induced intestinal injury through altering transcriptomic profile.Jun 30, 2020

Effects of Oridonin on growth performance and oxidative stress in broilers challenged with lipopolysaccharide.Sep 30, 2016

Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing the neuroinflammatory response.Sep 30, 2020

Hydroxytyrosol ameliorates oxidative challenge and inflammatory response associated with lipopolysaccharide-mediated sepsis.Aug 24, 2020

Oleuropein protects against lipopolysaccharide-induced sepsis and alleviates inflammatory responses in mice.Jul 24, 2020

"Fucoidan enhances the survival and sustains the number of splenic dendritic cells in mouse endotoxemia."Mar 31, 2011

2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevents lipopolysaccharide-induced depressive-like behaviours.Dec 31, 2016

6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment.Oct 31, 2018

A frankincense extract displayed anti-inflammatory, anti-oxidative, and hepatoprotective effects.Dec 31, 2017

A hydro-alcoholic extract of nigella sativa reduced the LPS-induced sickness behaviors in rats.Dec 31, 2015

A traditional Korean fermented soybean food exhibits anti-inflammatory activity which may have therapeutic value in allergic conditions such as asthma and atopic dermatitis. Sep 01, 2008

A water extract of Taraxacum mongolicum had a protective effect on lipopolysaccharide induced acute lung injury in mice.Jun 19, 2015

A. calamus prevented from memory deficits and stress through controlling oxidative stress and inflammation processes.Dec 31, 2017

Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.Mar 14, 2017

Acteoside has a protective and therapeutic effect on LPS-induced immunological liver injury in mice.Oct 31, 2009

Acteoside has beneficial effects on lipopolysaccharide-induced inflammation in acute lung injury.May 31, 2015

Actinidia arguta extract attenuates inflammasome activation: Potential involvement in NLRP3 ubiquitination.Feb 28, 2018

Aegle marmelos fruit extract attenuates Helicobacter pylori Lipopolysaccharide induced oxidative stress.Oct 18, 2015

AGE and RGE significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.Sep 30, 2014

Agrimony exhibits anti-inflammatory activity, substantiating its traditional uses for inflammation and allergic diseases. Jan 01, 2010

Allicin attenuates lipopolysaccharide‑induced acute lung injury.Mar 06, 2018

Alliin ameliorates DSS-induced ulcerative colitis and inhibits the inflammatory responses in LPS-stimulated RAW264.7 cells.Mar 29, 2017

Allyl isothiocyanate ameliorates dextran sodium sulfate-induced colitis.Jul 11, 2018

Alpha-linolenic acid protects against lipopolysaccharide-induced acute lung injury through anti-inflammatory and anti-oxidative pathways.Feb 17, 2020

Amygdalin reduces lipopolysaccharide-induced chronic liver injury.Nov 30, 2019

An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties.May 31, 2007

An extract of Stevia rebaudiana leaves and stevioside ameliorates lipopolysaccharide induced acute liver injury.Oct 31, 2017

An integrated network pharmacology and RNA-Seq approach for exploring the preventive effect of Lonicerae japonicae flos on LPS-induced acute lung injury.Sep 08, 2020

Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.Nov 27, 2017

Anthocyanin-rich fractions from red raspberries attenuate inflammation both in vitro and in vivo.Dec 31, 2013

Anti-inflammatory and antioxidant properties of black mulberry in a Model of LPS-induced sepsis.Dec 31, 2017

Anti-inflammatory effect of sulforaphane on LPS-stimulated RAW 264.7 cells and ob/ob mice.Oct 31, 2020

Anti-inflammatory effects of ginsenoside Rg1 and its metabolites ginsenoside Rh1 and 20(S)-protopanaxatriol.Sep 04, 2015

Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.Apr 14, 2016

Antibiotic-induced depletion of murine microbiota induces mild inflammation.Sep 30, 2015

Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.Dec 31, 2016

Antidepressant-like effect and mechanism of action of honokiol in lipopolysaccharide depression model.May 27, 2019

Antidepressant-like effects of β-caryophyllene on restraint plus stress-induced depression.Feb 16, 2020

Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.Apr 30, 2017

Antipyretic effects of citral and possible mechanisms of action. Sep 30, 2017

Lipopolysaccharide-Induced Toxicity

View the Evidence:
1070 Abstracts with Lipopolysaccharide-Induced Toxicity Research