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Lipopolysaccharide-Induced Toxicity
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405 Substances Researched for Lipopolysaccharide-Induced Toxicity
Name
AC
CK
Focus
Curcumin
51
68
Flavonoids
32
50
Ginsenosides
30
44
Vitamin C
14
35
Polyphenols
14
34
Resveratrol
19
30
DHA (Docosahexaenoic Acid)
3
22
Berberine
14
21
Paeoniflorin
13
20
Pomegranate
2
20
Puerarin
11
20
Dandelion
15
18
Fermented Foods and Beverages
7
18
Paeonol
11
18
Probiotics
5
18
Tanshinone IIA
14
18
Vitamin D
5
17
Honokiol
4
16
Sulforaphane
12
16
Astragaloside
11
15
Fucoidan
11
15
Isoflavones
4
15
Luteolin
11
15
Stilbenes
8
15
Astaxanthin
8
14
Safflower
10
14
Cannabidiol
9
13
Honeysuckle
8
13
Hydroxytyrosol
8
13
Melatonin
6
13
Strawberry
4
13
Fisetin
8
12
Licorice
8
12
Oridonin
8
12
Pterostilbene
7
12
Bee Venom
7
11
Echinacea
4
11
Eriodictyol
6
11
Ginger
7
11
Isoliquiritigenin
6
11
Myricetin
8
11
Quercetin
8
11
Sesamol
6
11
Asiatic Acid
8
10
Bacillus coagulans
1
10
Bilberry
1
10
Lactobacillus Acidophilus
1
10
Olive
1
10
Olive Oil
1
10
Punicalagin
6
10
Thymoquinone
6
10
Yoghurt
1
10
Citrus naringin
6
9
Lycopene
5
9
Patchouli
5
9
Zerumbone
5
9
Biochanin A
5
8
EGCG (Epigallocatechin gallate)
7
8
Genipin
6
8
Lactoferrin
6
8
Lotus
7
8
Nigella sativa (aka Black Seed)
4
8
Piperine
5
8
Shikonin
6
8
Blue Honeysuckle
4
7
Carvacrol
4
7
Citral
2
7
Genistein
6
7
Green Tea
4
7
Hops
4
7
Mangiferin
6
7
Mulberry
5
7
NAC (N-acetyl-L-cysteine)
5
7
P-Coumaric Acid
4
7
Peony
5
7
Red Sage
4
7
Rose
4
7
Rutin
4
7
Thymol
4
7
Verbascoside
5
7
Apigenin
6
6
Barley
3
6
Bifidobacterium Longum
3
6
Cannabis
4
6
Cordyceps sinensis
3
6
Crocin
4
6
Emodin
4
6
Frankincense
5
6
Oleocanthal
2
6
Panax Notoginseng
4
6
Phyllanthus amarus
4
6
Reishi Mushroom
6
6
Sea buckthorn
4
6
Selenium
3
6
Sesamin
3
6
Adlay
5
5
Anthocyanins
4
5
Ashwagandha
3
5
Blueberry
4
5
Caffeic acid phenethyl ester
1
5
Cannabinoids
4
5
Celery
3
5
Chrysin
4
5
Delta-tetrahydrocannabinol (THC)
4
5
Diosgenin
3
5
Elderberry
1
5
Ellagic Acid
3
5
Formononetin
3
5
Fucoxanthin
4
5
Gastrodin
4
5
Guduchi
1
5
Kaempferol
3
5
Krill
3
5
Lactobacillus rhamnosus GG
3
5
Naringenin
3
5
Nobiletin
3
5
Parthenolide
4
5
Phellinus Linteus
5
5
Piceatannol
4
5
Pine Needle
4
5
Purslane
3
5
Silibinin
3
5
Toona sinensis
4
5
Walnut
4
5
Zinc
3
5
Aloe Vera
2
4
Bay leaf
3
4
Black Tea
2
4
Burdock
2
4
Chrysanthemum Indicum
3
4
Eucalyptus
3
4
False Black Pepper
2
4
Ferulic acid
2
4
Garlic
2
4
Geraniol
2
4
Ginkgo biloba
3
4
Ginseng (Siberian)
2
4
Hemp Seed
3
4
Honey
2
4
Huperzine
2
4
Japanese cypress
2
4
Kiwifruit
3
4
Lactobacillus helveticus
2
4
Lactobacillus plantarum
2
4
Ligustrazine
4
4
Lupeol
2
4
Mangosteen
3
4
Mussel: Green-lipped (Perna canaliculus)
2
4
Phloretin
3
4
Red Clover
3
4
Rosemaric Acid
2
4
Soy
2
4
Tangeretin
3
4
Vanillin
4
4
Vitexins
3
4
Zataria multiflora
2
4
Agrimony
2
3
Allicin
2
3
Amygdalin (laetrile)
2
3
Angelica
3
3
Astragalus
2
3
Bai Zhu
3
3
Bee Propolis
3
3
Beta-Caryophyllene
2
3
Bitter Melon
2
3
Butterbur
2
3
Carnosic Acid
2
3
Chokeberry
2
3
Cinnamaldehyde
2
3
Coenzyme Q10
2
3
Crocetin
2
3
Diosmetin
2
3
Diosmin
2
3
Flaxseed
2
3
Gingerol
2
3
Glycyrrhizin
2
3
Gotu Kola
3
3
Hesperidin
2
3
Hydrangea
2
3
Loquat Leaves
3
3
Moringa oleifera
2
3
Neem
2
3
Omega-3 Fatty Acids
2
3
Polyunsaturated Fatty Acids (PUFAs)
2
3
Poria cocos
3
3
Prickly Pear Cactus
3
3
Radish
2
3
Rosmarinic acid
2
3
Salvia miltiorrhiza
2
3
Schisandra
2
3
Seaweed: Brown
3
3
Spikenard
3
3
Sweet Potato: Purple
2
3
Turmeric
3
3
Ubiquinol
3
3
Whey
2
3
Xanthohumol
2
3
Acai
1
2
Acorus calamus
1
2
Aduki bean
1
2
African Basil
1
2
Alpha Linolenic Acid
1
2
Amygdalin
1
2
Arctigenin
1
2
Arginine
1
2
Babchi
2
2
Bael
1
2
Belladonna
1
2
Bergamot
1
2
Beta-glucan
1
2
Bisdemethoxycurcumin
1
2
Black Pepper
1
2
Bromelain
2
2
Buckwheat
1
2
Butyrate
1
2
Caffeine
1
2
Capparis spinosa (caper)
1
2
Cardamonin
1
2
Carnosine
1
2
Catechin
2
2
Catechols
2
2
Celastrol
1
2
Centella asiatica
1
2
Chaste Tree (Chasteberry)
1
2
Chrysanthemum Morifolium
2
2
Clove
1
2
Cocoa
2
2
Coffee
1
2
Cordyceps Militaris
2
2
Corn Silk
1
2
Cucurbitacin E
2
2
Curry Leaves
1
2
Damnacanthal
1
2
Diallyl sulfide
1
2
Dogwood
2
2
Fiber
1
2
Fish Oil
1
2
Flaxseed Oil
1
2
Gallic Acid
1
2
Gamma-Oryzanol
1
2
Garden Cress (Lepidium sativum)
1
2
Gardenia
1
2
Ginseng
1
2
Ginseng (Korean)
1
2
Glucosamine
1
2
Gold (nanoparticles)
1
2
Grape Seed Extract
1
2
Hibiscus
2
2
Hibiscus sabdariffa
1
2
Histidine
1
2
Hydrogen Water
1
2
Indole-3-Carbinol
1
2
Isoquercitrin
1
2
Isothiocyanates
1
2
Justicia gendarussa
2
2
Lactobacillus casei
1
2
Lactobacillus gasseri
1
2
Lactobacillus reuteri
1
2
Lactobacillus sakei
1
2
Lignans
2
2
Lion's Mane (Hericium Erinaceus)
2
2
Liquiritigenin
1
2
Lithium
1
2
MSM (Methylsulfonylmethane)
2
2
Magnesium Sulfate
1
2
Maitake Mushroom
2
2
Manuka Honey
2
2
Medicinal Mushrooms
2
2
Modified Citrus Pectin
1
2
Motherwort
2
2
Mushrooms: All
2
2
Noni
1
2
Oleuropein
1
2
Orthosiphon
2
2
Palmitoylethanolamide
1
2
Perilla
2
2
Perillaldehyde
1
2
Pine Bark Extract
1
2
Pine Cone
2
2
Piperlongumine
1
2
Plantago asiatica
1
2
Potato
1
2
Procyanidin B2
2
2
Propolis: Brazillian
1
2
Pycnogenol (Pine Bark)
2
2
Raspberry
1
2
Red Marine Algae
1
2
Riboflavin (Vitamin B-2)
1
2
Rosemary
2
2
Saffron
1
2
Sage
1
2
Saw Palmetto
1
2
Spirulina
1
2
Sprouts
1
2
Stevia
1
2
Stigmasterol
1
2
Thistle
2
2
Thuja
1
2
Turmerones
1
2
Urolithin A
2
2
Vitamin B-12
1
2
Vitamin B-12: Hydroxocobalamin
1
2
Vitamin B-6
1
2
White Mulberry
2
2
acetyl-11-keto-beta-boswellic acid
1
2
6-Shogaol
1
1
Acacia catechu
1
1
Almond
1
1
Andrographis
1
1
Antrodia camphorata
1
1
Apocynin
1
1
Apple
1
1
Apple Pectin
1
1
Artemisinin
1
1
Artesunate
1
1
Ayahuasca
1
1
Baicalein
1
1
Barley Grass
1
1
Benzyl isothiocyanate
1
1
Beta Sitosterol
1
1
Beta-Elemene
1
1
Black Raspberry
1
1
Blackberry
1
1
Boron
1
1
Carnosol
1
1
Chaga Mushroom (Inonotus obliquus)
1
1
Chamomile
1
1
Cherry: All Varieties
1
1
Chicoric Acid
1
1
Chlorogenic Acid
1
1
Citric Acid
1
1
Coconut
1
1
Cryptoxanthin
1
1
Cucumber
1
1
Cucurbitacin B
1
1
Curcumin: Degradiation byproducts
1
1
Curcumin: Lipidated
1
1
Curcuminoids
1
1
Daidzein
1
1
Demethoxycurcumin
1
1
Eugenol
1
1
Euphorbia peplus
1
1
False Daisy
1
1
Fig
1
1
Flowers
1
1
Galactooligosaccharides
1
1
Garlic: Aged
1
1
Glycyrrhiza uralensis
1
1
Green Coffee Bean
1
1
Guggul
1
1
Hawthorn
1
1
Hazelnut
1
1
Horseradish
1
1
Horsetail
1
1
Hyaluronic Acid
1
1
Jujube
1
1
Juniper
1
1
Knema laurina
1
1
Kombucha Tea
1
1
Lactobacillus rhamnosus
1
1
Lauric acid
1
1
Lavender: Essential Oil
1
1
Linoleic acid
1
1
Longan
1
1
Macadamia
1
1
Maple Syrup
1
1
Matairesinol
1
1
Methionine
1
1
Mugwort
1
1
Myrrh
1
1
Nuts
1
1
Oak
1
1
Oligosaccharides
1
1
Panax Ginseng
1
1
Passion Flower
1
1
Peppermint
1
1
Persimmon
1
1
Phenethyl isothiocyanate
1
1
Pistachio nut
1
1
Plantago
1
1
Polyacetylenes
1
1
Pomegranate Peel
1
1
Pomegranate flower
1
1
Prebiotics
1
1
Prunella vulgaris
1
1
Purple Carrots
1
1
Quince
1
1
Red Cabbage
1
1
Rhubarb
1
1
Rice: Black
1
1
Royal Jelly
1
1
Saccharomyces Boulardii
1
1
Sessile Joyweed
1
1
Shiitake Mushroom
1
1
Sour Cherry
1
1
Syrian rue
1
1
Tea
1
1
Tetrahydrocurcumin
1
1
Thyme
1
1
Tualang Honey
1
1
Vitamin E: Gamma-tocotrienol
1
1
Vitex negundo
1
1
Wheat Germ
1
1
Willow Bark
1
1
Xanthones
1
1
15 Problem Substances Researched for Lipopolysaccharide-Induced Toxicity
Name
AC
CK
Focus
Insulin
1
5
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
3
3
Pesticides
2
3
Aluminum
1
2
Antibiotics
1
2
Aspirin
1
2
Chlorpyrifos
1
2
Diclofenac
1
2
Electronic Cigarettes
1
2
Fluoxetine (trade name Prozac)
1
2
Oseltamivir (trade name Tamiflu)
1
2
Selective Serotonin Reuptake Inhibitors (SSRIs)
1
2
Glyphosate
1
1
Heavy Metals
1
1
Ibuprofen
1
1
7 Therapeutic Actions Researched for Lipopolysaccharide-Induced Toxicity
Name
AC
CK
Focus
Exercise
1
10
Exercise: Running
1
10
Microbiota Transfer Therapy
2
4
Homeopathic Treatment
1
2
Laser Treatment: Low-Level
1
2
Ultrasound therapy
1
2
Fasting/Caloric Restriction
1
1
3 Problematic Actions Researched for Lipopolysaccharide-Induced Toxicity
Name
AC
CK
Focus
Electromagnetic Field Harms
1
5
Electromagnetic Radiation
1
5
Western Diet
2
4
Research Articles
1073
Cumulative Knowledge Score
1736
Overall Research Rating
EXCELLENT
View the Evidence:
1364 Abstracts with Lipopolysaccharide-Induced Toxicity Research
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[+]
Bilberry has anti-inflammatory properties.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID:
20119859
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.
Dec 06, 2006
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2006 Dec 6;108(3):398-406. Epub 2006 Jun 2. PMID:
16824715
Article Published Date
: Dec 06, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia.
May 16, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 May 17. Epub 2018 May 17. PMID:
29770393
Article Published Date
: May 16, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Colorectal Cancer
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Consumption of pomegranate extract decreased endotoxemia in overweight-obese individuals by reshaping the gut microbiota.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2018 Jun ;62(11):e1800160. Epub 2018 May 17. PMID:
29665619
Article Published Date
: May 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
C-Reactive Protein
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Microbiota
[+]
Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID:
25948780
Article Published Date
: Jun 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Bacillus coagulans
Diseases
:
C-Reactive Protein
,
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Microbiota
[+]
DHA diet supplementation attenuated cytokine production after exercise.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Physiol Biochem. 2016 Sep ;72(3):421-34. Epub 2016 May 2. PMID:
27139422
Article Published Date
: Aug 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Extra virgin olive oil mitigates postprandial lipopolysaccharide-induced inflammation and oxidative stress.
Mar 01, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2019 Mar ;58(2):843-851. Epub 2018 May 16. PMID:
29766292
Article Published Date
: Mar 01, 2019
Study Type
: Human Study
Additional Links
Substances
:
Olive
,
Olive Oil
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidant
,
Antioxidant Effects
[+]
Honokiol protects pulmonary microvascular endothelial barrier against lipopolysaccharide-induced ARDS.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2018 Oct 1 ;210:86-95. Epub 2018 Aug 29. PMID:
30171880
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study, Human In Vitro, Human Study
Additional Links
Substances
:
Honokiol
Diseases
:
Acute Respiratory Distress Syndrome
,
Lipopolysaccharide-Induced Toxicity
[+]
Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.
Feb 27, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2016 Feb 28 ;115(4):567-75. Epub 2016 Jan 15. PMID:
26769562
Article Published Date
: Feb 27, 2016
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus Acidophilus
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interferon Gamma Reducer
,
Interleukin-10 upregulation
,
Interleukin-4 upregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Lithium can increase brain 17-hydroxy-DHA formation, indicating a new and potentially important therapeutic action of lithium.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Lipid Res. 2010 May;51(5):1049-56. Epub 2009 Dec 29. PMID:
20040630
Article Published Date
: May 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
Bipolar Disorder
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Moderate running exercise prevents excessive immune system activation.
Feb 18, 2019
Click here to read the entire abstract
Pubmed Data
: Physiol Behav. 2019 Feb 19. Epub 2019 Feb 19. PMID:
30794851
Article Published Date
: Feb 18, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Therapeutic Actions
:
Exercise: Running
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Preeclampsia patients had gut microbiota dysbiosis and increased plasma lipopolysaccharide and trimethylamine-N-oxide levels.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Cell Infect Microbiol. 2019 ;9:409. Epub 2019 Dec 3. PMID:
31850241
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
,
Pre-Eclampsia
Additional Keywords
:
Risk Factors
[+]
Probiotic administration in the elderly normalises the response to endotoxin, and modulates activation markers in blood phagocytes, and therefore may help reduce low-grade chronic inflammation.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2009;61(5):680-6. PMID:
19353762
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Probiotics
,
Yoghurt
Diseases
:
Aging
,
Endotoxemia
,
Immune Disorders: Low Immune Function
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Immunomodulatory
[+]
Puerarin acts as an anti-inflammatory agent by blocking NF-kappaB signalling.
Jul 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2010 Aug ;107(2):637-42. Epub 2010 Mar 22. PMID:
20346059
Article Published Date
: Jul 31, 2010
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones
Diseases
:
Angina Pectoris
,
Atherosclerosis
,
C-Reactive Protein
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
There is a measurable systemic inflammatory response in first trimester pregnancy failure.
Jan 31, 2012
Click here to read the entire abstract
Pubmed Data
: Hum Reprod. 2012 Feb ;27(2):349-57. Epub 2011 Nov 29. PMID:
22131390
Article Published Date
: Jan 31, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Miscarriage
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2014 ;2014:426740. Epub 2014 Aug 1. PMID:
25253919
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Pneumonia
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitamin D partially reversed the effect of lipopolysaccharide induced imbalances and protected patients with T2DM and DNU.
Aug 28, 2016
Click here to read the entire abstract
Pubmed Data
: Genet Mol Res. 2016 Aug 29 ;15(3). Epub 2016 Aug 29. PMID:
27706649
Article Published Date
: Aug 28, 2016
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Diabetes Mellitus: Type 2
,
Diabetic Nephropathy
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
50 Hz magnetic fields and lipopolysaccharides synergistically reduce cell viability in vitro.
Jan 10, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Radiat Biol. 2016 10 ;92(10):583-9. Epub 2016 Jul 19. PMID:
27430265
Article Published Date
: Jan 10, 2016
Study Type
: Human In Vitro
Additional Links
Diseases
:
DNA damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Radiation Induced Illness
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
[+]
Alpha-bisobolol inhibits lipopolysaccharide-induced inflammation.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2011 Oct ;49(10):2580-5. Epub 2011 Jul 13. PMID:
21771629
Article Published Date
: Oct 01, 2011
Study Type
: Human In Vitro
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Caffeic acid phenethyl ester could be effective for treating of periodontal diseases.
Nov 06, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2016 Nov 7. Epub 2016 Aug 7. PMID:
27832944
Article Published Date
: Nov 06, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Periodontal Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Citral inhibits LPS-induced inflammatory response via activating PPAR-γ which attenuates NF-κB activation.
Dec 10, 2015
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2015 Dec 11. Epub 2015 Dec 11. PMID:
26658749
Article Published Date
: Dec 10, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Citral
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Elderberry and elderflower extracts inhibit nitric oxide production in lipopolysaccharide-activated macrophages.
Mar 08, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Mol Sci. 2017 Mar 8 ;18(3). Epub 2017 Mar 8. PMID:
28282861
Article Published Date
: Mar 08, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Elderberry
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Hydrocortisone and ascorbic acid synergistically prevent and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunction.
Jan 10, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Chest. 2017 11 ;152(5):954-962. Epub 2017 Jul 21. PMID:
28739448
Article Published Date
: Jan 10, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Vitamin C
Diseases
:
Endothelial Dysfunction
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Luteolin and apigenin derived glycosides from Alphonsea elliptica abrogate LPS-induced inflammatory responses in human plasma.
Apr 19, 2021
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2021 Apr 20 ;275:114120. Epub 2021 Apr 20. PMID:
33857595
Article Published Date
: Apr 19, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
,
Luteolin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2012 Sep ;53(2):154-65. Epub 2012 Feb 21. PMID:
22348531
Article Published Date
: Aug 31, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Prostaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
[+]
Metabolomics profiling reveals berberine-inhibited inflammatory response in human gingival fibroblasts.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:940224. Epub 2022 Aug 22. PMID:
36071855
Article Published Date
: Dec 31, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Berberine
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oleocanthal inhibits catabolic and inflammatory mediators in LPS-activated human primary osteoarthritis chondrocytes.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;49(6):2414-2426. Epub 2018 Sep 27. PMID:
30261513
Article Published Date
: Dec 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Oleocanthal
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Plant polyphenols mitigate the pro-inflammatory and pro-oxidant adipocyte response to lipopolysaccharides.
Jan 01, 2017
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 05 ;119:303-312. Epub 2017 Feb 27. PMID:
28249816
Article Published Date
: Jan 01, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Puerarin may improve mitochondrial respiratory function and energy metabolism, increasing the vulnerability of HUVECs to an inflammatory state.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2021 ;2021:6659240. Epub 2021 Feb 27. PMID:
33728025
Article Published Date
: Dec 31, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Puerarin
Diseases
:
Atherosclerosis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Resveratrol could be a prime candidate in ameliorating dysfunctioning adipose tissue induced by inflammatory stimulation.
Jan 01, 2016
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2016 ;11(7):e0159747. Epub 2016 Jul 20. PMID:
27438462
Article Published Date
: Jan 01, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
,
Stilbenes
Diseases
:
Inflammation
,
Insulin Resistance
,
Lipopolysaccharide-Induced Toxicity
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Problem Substances
:
Insulin
[+]
Strawberry extracts efficiently counteract inflammatory stress induced by the endotoxin lipopolysaccharide.
Feb 15, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Feb 16. Epub 2018 Feb 16. PMID:
29458159
Article Published Date
: Feb 15, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Strawberry
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
T. cordifolia dry leaf extracts possess antioxidant and anti-inflammatory properties.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2019 Aug ;61:152831. Epub 2019 Jan 10. PMID:
31035042
Article Published Date
: Jul 31, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Guduchi
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
These results showed for the first time a clear and a dose-dependent protective effect of strawberry extract on LPS-induced damage in HDF cell line.
Jan 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2017 Jan 21 ;22(1). Epub 2017 Jan 21. PMID:
28117711
Article Published Date
: Jan 20, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Strawberry
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
α-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.
Jan 01, 2014
Click here to read the entire abstract
Pubmed Data
: Curr Pharm Biotechnol. 2014 ;15(2):173-81. PMID:
24894548
Article Published Date
: Jan 01, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Diosgenin prevents microglial activation and protects dopaminergic neurons from lipopolysaccharide-induced neural damage.
Sep 25, 2021
Click here to read the entire abstract
Pubmed Data
: Int J Mol Sci. 2021 Sep 26 ;22(19). Epub 2021 Sep 26. PMID:
34638697
Article Published Date
: Sep 25, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Brain: Microglial Activation
,
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Erinacine A prevents lipopolysaccharide-mediated glial cell activation to protect dopaminergic neurons against inflammatory factor-induced cell death.
Jan 11, 2022
Click here to read the entire abstract
Pubmed Data
: Int J Mol Sci. 2022 Jan 12 ;23(2). Epub 2022 Jan 12. PMID:
35054997
Article Published Date
: Jan 11, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lion's Mane (Hericium Erinaceus)
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Isorhamnetin alleviates lipopolysaccharide-induced acute lung injury.
May 31, 2022
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2022 Jun ;44(3):387-399. Epub 2022 Mar 21. PMID:
35306954
Article Published Date
: May 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Apoptotic
,
Autophagy Up-regulation
,
NF-kappaB Inhibitor
[+]
Oral administration of Ulmus davidiana extract suppresses interleukin-1β expression in LPS-induced immune responses and lung injury.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Genes Genomics. 2020 01 ;42(1):87-95. Epub 2019 Nov 17. PMID:
31736005
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Elm tree
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Pterostilbene interferes with lipopolysaccharide-induced myocardial injury,
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2022 ;13:862187. Epub 2022 Mar 24. PMID:
35399278
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pterostilbene
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Interleukin-1 alpha downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Salvianolic acid B attenuates the inflammatory response in atherosclerosis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Immunopathol Pharmacol. 2022 Jan-Dec;36:3946320221079468. PMID:
35285334
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Salvia miltiorrhiza
Diseases
:
Atherosclerosis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Tanshinone IIA protected against lipopolysaccharide-induced brain injury.
Jul 31, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Aug 1 ;13(15):8304-8312. Epub 2022 Aug 1. PMID:
35839080
Article Published Date
: Jul 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Aloin suppresses lipopolysaccharide-induced acute lung injury by inhibiting NLRP3/NF-κB via activation of SIRT1 in mice.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2020 Aug ;42(4):306-313. Epub 2020 May 18. PMID:
32419528
Article Published Date
: Jul 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
SIRT1 Activator
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baicalin protects LPS-induced blood-brain barrier damage and activates Nrf2-mediated antioxidant stress pathway
Jun 30, 2021
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2021 Jul ;96:107725. Epub 2021 May 28. PMID:
34162131
Article Published Date
: Jun 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary genistein supplementation protects against lipopolysaccharide-induced intestinal injury through altering transcriptomic profile.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Poult Sci. 2020 Jul ;99(7):3411-3427. Epub 2020 Apr 15. PMID:
32616235
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
,
Gastroprotective
[+]
Effects of Oridonin on growth performance and oxidative stress in broilers challenged with lipopolysaccharide.
Sep 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Poult Sci. 2016 Oct 1 ;95(10):2281-9. Epub 2016 May 3. PMID:
27143760
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Oridonin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Nrf2 activation
[+]
Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing the neuroinflammatory response.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2020 Oct 1 ;530(4):658-664. Epub 2020 Aug 5. PMID:
32768191
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Brain-derived neurotrophic factor modulator
[+]
Hydroxytyrosol ameliorates oxidative challenge and inflammatory response associated with lipopolysaccharide-mediated sepsis.
Aug 24, 2020
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2020 Aug 25:960327120949618. Epub 2020 Aug 25. PMID:
32840384
Article Published Date
: Aug 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Hydroxytyrosol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oleuropein protects against lipopolysaccharide-induced sepsis and alleviates inflammatory responses in mice.
Jul 24, 2020
Click here to read the entire abstract
Pubmed Data
: IUBMB Life. 2020 Jul 25. Epub 2020 Jul 25. PMID:
32710811
Article Published Date
: Jul 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Oleuropein
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
"Fucoidan enhances the survival and sustains the number of splenic dendritic cells in mouse endotoxemia."
Mar 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2011 Apr ;15(2):89-94. Epub 2011 Apr 30. PMID:
21660148
Article Published Date
: Mar 31, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
[+]
2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevents lipopolysaccharide-induced depressive-like behaviours.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Behav Pharmacol. 2017 08 ;28(5):365-374. PMID:
28410266
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Anxiety
,
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment.
Oct 31, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Nov ;107:1523-1529. Epub 2018 Sep 5. PMID:
30257370
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gingerol
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A comparative study of the hepatoprotective effect of Centella asiatica extract on lipopolysaccharide/d-galactosamine-induced acute liver injury.
Nov 14, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Nov 15 ;13(11). Epub 2021 Nov 15. PMID:
34836346
Article Published Date
: Nov 14, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A frankincense extract displayed anti-inflammatory, anti-oxidative, and hepatoprotective effects.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2018 ;9:387. Epub 2018 Apr 20. PMID:
29731716
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
A hydro-alcoholic extract of nigella sativa reduced the LPS-induced sickness behaviors in rats.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Avicenna J Phytomed. 2016 Jan-Feb;6(1):104-16. PMID:
27247927
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Lipopolysaccharide-Induced Toxicity
Additional Keywords
:
Plant Extracts
[+]
A standardised Andrographis paniculata Burm. Nees aqueous extract prevents Lipopolysaccharide-induced cognitive deficits.
Feb 28, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Adv Res. 2019 Mar ;16:87-97. Epub 2018 Nov 30. PMID:
30899592
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A traditional Korean fermented soybean food exhibits anti-inflammatory activity which may have therapeutic value in allergic conditions such as asthma and atopic dermatitis.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2008 Sep;11(3):539-43. PMID:
18800904
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Isoflavones
,
Soy
Diseases
:
Allergies
,
Asthma
,
Atopic Dermatitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Lipoxygenase Inhibitors
Additional Keywords
:
Plant Extracts
[+]
A water extract of Taraxacum mongolicum had a protective effect on lipopolysaccharide induced acute lung injury in mice.
Jun 19, 2015
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2015 Jun 20 ;168:349-55. Epub 2015 Apr 8. PMID:
25861954
Article Published Date
: Jun 19, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
,
Lung Injury: Neutrophil-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
A. calamus prevented from memory deficits and stress through controlling oxidative stress and inflammation processes.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Prev Med. 2018 ;9:85. Epub 2018 Oct 12. PMID:
30450168
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Acorus calamus
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.
Mar 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut Liver. 2017 Mar 15 ;11(2):243-252. PMID:
27965474
Article Published Date
: Mar 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Acai
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acteoside has a protective and therapeutic effect on LPS-induced immunological liver injury in mice.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2009 Nov ;75(14):1463-9. Epub 2009 Jun 22. PMID:
19548187
Article Published Date
: Oct 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Acteoside has beneficial effects on lipopolysaccharide-induced inflammation in acute lung injury.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2015 Jun 1 ;285(2):128-35. Epub 2015 Apr 19. PMID:
25902336
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Actinidia arguta extract attenuates inflammasome activation: Potential involvement in NLRP3 ubiquitination.
Feb 28, 2018
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2018 Mar 1 ;213:159-165. Epub 2017 Nov 21. PMID:
29174375
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Kiwifruit
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Plant Extracts
[+]
Aegle marmelos fruit extract attenuates Helicobacter pylori Lipopolysaccharide induced oxidative stress.
Oct 18, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 Oct 19 ;15:375. Epub 2015 Oct 19. PMID:
26482072
Article Published Date
: Oct 18, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Gastric Ulcer
,
Helicobacter Pylori Infection
,
Lipid Peroxidation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
AGE and RGE significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2014 Oct ;17(10):1057-63. Epub 2014 Sep 19. PMID:
25238199
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Agrimony exhibits anti-inflammatory activity, substantiating its traditional uses for inflammation and allergic diseases.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Immunol Invest. 2010 Jan;39(2):159-70. PMID:
20136621
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Agrimony
Diseases
:
Allergies
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Science Confirms Tradition
[+]
Alleviation of cognitive impairment by gut microbiota lipopolysaccharide production-suppressing Lactobacillus plantarum and Bifidobacterium longum.
Oct 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Funct. 2021 Nov 1 ;12(21):10750-10763. Epub 2021 Nov 1. PMID:
34608923
Article Published Date
: Oct 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Bifidobacterium Longum
,
Lactobacillus plantarum
Diseases
:
Cognitive Decline/Dysfunction
,
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Neuroprotective Agents
[+]
Allicin attenuates lipopolysaccharide‑induced acute lung injury.
Mar 06, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 Mar 7. Epub 2018 Mar 7. PMID:
29512749
Article Published Date
: Mar 06, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alliin ameliorates DSS-induced ulcerative colitis and inhibits the inflammatory responses in LPS-stimulated RAW264.7 cells.
Mar 29, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2017 Mar 30. Epub 2017 Mar 30. PMID:
28371322
Article Published Date
: Mar 29, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Allyl isothiocyanate ameliorates dextran sodium sulfate-induced colitis.
Jul 11, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2018 Jul 12 ;19(7). Epub 2018 Jul 12. PMID:
30002285
Article Published Date
: Jul 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Isothiocyanates
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Alpha lipoic acid ameliorates detrimental effects of maternal lipopolysaccharides exposure on prefrontal white matter in adult male offspring rats.
Oct 01, 2021
Click here to read the entire abstract
Pubmed Data
: J Chem Neuroanat. 2021 Oct 2 ;118:102038. Epub 2021 Oct 2. PMID:
34610418
Article Published Date
: Oct 01, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Neuroprotective Agents
[+]
Alpha-linolenic acid protects against lipopolysaccharide-induced acute lung injury through anti-inflammatory and anti-oxidative pathways.
Feb 17, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Microb Pathog. 2020 Feb 18 ;142:104077. Epub 2020 Feb 18. PMID:
32084579
Article Published Date
: Feb 17, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha Linolenic Acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ameliorative effect of thymoquinone-loaded PLGA nanoparticles on chronic lung injury induced by repetitive intratracheal instillation of lipopolysaccharide.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2021 ;2021:5511523. Epub 2021 May 28. PMID:
34136063
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Transforming growth factor beta (TGF-β) upregulation
[+]
Ameliorative effects of oleuropein on lipopolysaccharide-induced acute lung injury.
Sep 12, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Inflammation. 2021 Sep 13. Epub 2021 Sep 13. PMID:
34515957
Article Published Date
: Sep 12, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Oleuropein
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Antioxidants
[+]
Amygdalin reduces lipopolysaccharide-induced chronic liver injury.
Nov 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):2688-2697. PMID:
31257932
Article Published Date
: Nov 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin (laetrile)
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties.
May 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2007 Jun ;59(6):891-7. PMID:
17637182
Article Published Date
: May 31, 2007
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Celery
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
An extract of Stevia rebaudiana leaves and stevioside ameliorates lipopolysaccharide induced acute liver injury.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Nov ;95:1040-1050. Epub 2017 Sep 13. PMID:
28922721
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Stevia
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
An integrated network pharmacology and RNA-Seq approach for exploring the preventive effect of Lonicerae japonicae flos on LPS-induced acute lung injury.
Sep 08, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Sep 9 ;264:113364. Epub 2020 Sep 9. PMID:
32916233
Article Published Date
: Sep 08, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Honeysuckle
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Andrographolide ameliorates d-galactosamine/lipopolysaccharide-induced acute liver injury by activating Nrf2 signaling pathway.
Jun 19, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Jun 20 ;8(25):41202-41210. PMID:
28465482
Article Published Date
: Jun 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Andrographolide ameliorates rheumatoid arthritis.
Oct 10, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Oct 11 ;20(20). Epub 2019 Oct 11. PMID:
31614480
Article Published Date
: Oct 10, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
,
Andrographolide
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Andrographolide inhibits inflammatory responses in LPS-stimulated macrophages and murine acute colitis.
Jan 11, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biochem Pharmacol. 2019 12 ;170:113646. Epub 2019 Sep 20. PMID:
31545974
Article Published Date
: Jan 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Andrographolide protects against LPS-induced acute lung injury by inactivation of NF-κB.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(2):e56407. Epub 2013 Feb 21. PMID:
23437127
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Andrographis
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Acta Pharm Sin B. 2016 May ;6(3):205-11. Epub 2016 Mar 22. PMID:
27175331
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Andrographolide
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
[+]
Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.
Nov 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Nov 28 ;18(12). Epub 2017 Nov 28. PMID:
29182579
Article Published Date
: Nov 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
[+]
Anthocyanin-rich fractions from red raspberries attenuate inflammation both in vitro and in vivo.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2014 ;4:6234. Epub 2014 Aug 29. PMID:
25167935
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Raspberry
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory and antioxidant properties of black mulberry in a Model of LPS-induced sepsis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:5048031. Epub 2018 Nov 7. PMID:
30524657
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Mulberry
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory effect of sulforaphane on LPS-stimulated RAW 264.7 cells and ob/ob mice.
Oct 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Vet Sci. 2020 Nov ;21(6):e91. PMID:
33263238
Article Published Date
: Oct 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory effects of ginsenoside Rg1 and its metabolites ginsenoside Rh1 and 20(S)-protopanaxatriol.
Sep 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Sep 5 ;762:333-43. Epub 2015 Jun 6. PMID:
26054809
Article Published Date
: Sep 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.
Apr 14, 2016
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2016 Apr 15 ;106:82-93. Epub 2016 Mar 3. PMID:
26947453
Article Published Date
: Apr 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Bone Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Antibiotic-induced depletion of murine microbiota induces mild inflammation.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: Microb Ecol. 2015 Oct ;70(3):835-48. Epub 2015 Apr 21. PMID:
25896428
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Antibiotic Toxicity
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Additional Keywords
:
Microbiota
Problem Substances
:
Antibiotics
[+]
Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2017 ;11:103-121. Epub 2016 Dec 28. PMID:
28096658
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curry Leaves
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Apoptotic
[+]
Antidepressant and anxiolytic-like effects of ayahuasca in rats subjected to LPS-induced neuroinflammation.
Jul 13, 2022
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2022 Jul 14 ;434:114007. Epub 2022 Jul 14. PMID:
35843462
Article Published Date
: Jul 13, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ayahuasca
Diseases
:
Brain Inflammation
,
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Antidepressant-like effect and mechanism of action of honokiol in lipopolysaccharide depression model.
May 27, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Molecules. 2019 May 28 ;24(11). Epub 2019 May 28. PMID:
31141940
Article Published Date
: May 27, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interferon Gamma Reducer
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antidepressant-like effects of solidagenone on mice with bacterial lipopolysaccharide (LPS)-induced depression.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2020 10 1 ;395:112863. Epub 2020 Aug 17. PMID:
32818537
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Goldenrod
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antidepressant-like effects of β-caryophyllene on restraint plus stress-induced depression.
Feb 16, 2020
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2020 Feb 17 ;380:112439. Epub 2019 Dec 17. PMID:
31862467
Article Published Date
: Feb 16, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Beta-Caryophyllene
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
Additional Keywords
:
Endocannabinoid System
[+]
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 May ;46:124-132. Epub 2017 Mar 7. PMID:
28282576
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Paeonol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Failure: Acute
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Antipyretic effects of citral and possible mechanisms of action.
Sep 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Inflammation. 2017 Oct ;40(5):1735-1741. PMID:
28667503
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Citral
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-pyretic
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti‑inflammatory effects of Panax notoginseng saponins ameliorate acute lung injury induced by oleic acid and lipopolysaccharide.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2014 Sep ;10(3):1400-8. Epub 2014 Jun 16. PMID:
24938646
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Panax Notoginseng
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Arctigenin has anti-inflammatory and antioxidative effects on LPS-induced acute lung injury.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2015 Aug ;38(4):1406-14. PMID:
25616905
Article Published Date
: Jul 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Arctiin prevents LPS-induced acute lung injury via inhibition of PI3K/AKT signaling pathway.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2018 Dec ;41(6):2129-2135. PMID:
30116933
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Burdock
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Aronia melanocarpa extract fermented by Lactobacillus plantarum EJ2014 modulates immune response in mice.
Aug 10, 2021
Click here to read the entire abstract
Pubmed Data
: Antioxidants (Basel). 2021 Aug 11 ;10(8). Epub 2021 Aug 11. PMID:
34439524
Article Published Date
: Aug 10, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Chokeberry
,
Fermented Foods and Beverages
,
Lactobacillus plantarum
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Immunomodulatory
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ascorbic acid attenuated the inflammatory response and fibrosis in the lungs of rats treated with lipopolysaccharide.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: SAGE Open Med. 2019 ;7:2050312119828260. Epub 2019 Feb 4. PMID:
30783524
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Fibrosis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
[+]
Ascorbic acid attenuates lipopolysaccharide-induced acute lung injury.
May 31, 2011
Click here to read the entire abstract
Pubmed Data
: Crit Care Med. 2011 Jun ;39(6):1454-60. PMID:
21358394
Article Published Date
: May 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Ascorbic acid modulates in vitro the function of macrophages from mice with endotoxic shock.
Dec 31, 1999
Click here to read the entire abstract
Pubmed Data
: Immunopharmacology. 2000 Jan ;46(1):89-101. PMID:
10665783
Article Published Date
: Dec 31, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Shock: Endotoxic
Pharmacological Actions
:
Antioxidants
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Asiatic acid inhibits lipopolysaccharide-induced acute lung injury in mice.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2016 Oct ;39(5):1642-8. PMID:
27395046
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astaxanthin ameliorates lipopolysaccharide-induced neuroinflammation, oxidative stress and memory dysfunction.
Feb 17, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2019 Feb 18 ;17(2). Epub 2019 Feb 18. PMID:
30781690
Article Published Date
: Feb 17, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Astaxanthin ameliorates the behavioural deficits of prenatal maternal LPS-exposure.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Neurosci. 2016 ;17(1):11. Epub 2016 Feb 8. PMID:
26856812
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Prenatal Chemical Exposures
Pharmacological Actions
:
Antioxidants
[+]
Astaxanthin ameliorates the lipopolysaccharides-induced subfertility.
Jun 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Dose Response. 2019 Jul-Sep;17(3):1559325819878537. Epub 2019 Sep 25. PMID:
31598118
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Infertility: Male
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Fertility Agents: Male
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Astaxanthin inhibits microglia M1 activation against inflammatory injury triggered by lipopolysaccharide through down-regulating miR-31-5p.
Dec 21, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Dec 22:118943. Epub 2020 Dec 22. PMID:
33359248
Article Published Date
: Dec 21, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
MicroRNA modulator
[+]
Astaxanthin prevents against lipopolysaccharide-induced acute lung injury and sepsis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2019 ;11(3):1884-1894. Epub 2019 Mar 15. PMID:
30972212
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Astaxanthin protects dendritic cells from lipopolysaccharide-induced immune dysfunction.
Jun 16, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2021 Jun 17 ;19(6). Epub 2021 Jun 17. PMID:
34204220
Article Published Date
: Jun 16, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Immunomodulatory
,
Nrf2 activation
[+]
Astaxanthin suppresses lipopolysaccharide‑induced myocardial injury.
Aug 18, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2020 Aug 19. Epub 2020 Aug 19. PMID:
32945516
Article Published Date
: Aug 18, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astilbin alleviates lipopolysaccharide -induced acute respiratory distress syndrome.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Jul ;36:51-58. Epub 2016 Apr 22. PMID:
27111514
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragalin reduces lipopolysaccharide-induced acute lung injury in rats via induction of heme oxygenase-1.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2019 Aug ;42(8):704-711. Epub 2019 Jun 27. PMID:
31250343
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Astragaloside IV alleviates lipopolysaccharide-induced acute kidney injury.
Mar 21, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Sci Monit. 2017 Mar 22 ;23:1413-1420. Epub 2017 Mar 22. PMID:
28328867
Article Published Date
: Mar 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Inflammation
,
Kidney Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragaloside IV alleviates lipopolysaccharide‐induced preeclampsia‐like phenotypes via suppressing the inflammatory responses.
Oct 21, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Kaohsiung J Med Sci. 2020 Oct 22. Epub 2020 Oct 22. PMID:
33089927
Article Published Date
: Oct 21, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Pre-Eclampsia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
[+]
Astragaloside IV protects rat gastric mucosa against aspirin-induced damage.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Dec ;41:47-55. Epub 2016 Nov 2. PMID:
27816726
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Aspirin-Induced Toxicity
,
Gastric Ulcer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Aspirin
[+]
Astragaloside IV suppresses inflammatory mediator production in synoviocytes and collagen‑induced arthritic rats.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2016 Apr ;13(4):3289-96. Epub 2016 Feb 22. PMID:
26936538
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Arthritis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Astragaloside IV-targeting miRNA-1 attenuates lipopolysaccharide-induced cardiac dysfunction.
Jun 14, 2021
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2021 Jun 15 ;275:119414. Epub 2021 Mar 24. PMID:
33774032
Article Published Date
: Jun 14, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Autophagy Inhibitors
,
Cardioprotective
[+]
Attenuating effect of Ginsenoside Rb1 on LPS-induced lung injury in rats.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Inflamm (Lond). 2014 ;11(1):40. Epub 2014 Dec 5. PMID:
25530718
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
B. serrata can act as a potent redox scavenger against LPS-induced inflammation.
Jul 31, 2022
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2022 Aug ;49(8):7425-7435. Epub 2022 Jun 18. PMID:
35716287
Article Published Date
: Jul 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Baicalin alleviates lipopolysaccharide-induced neuroglial activation and inflammatory factors activation in hippocampus of adult mice.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Lab Anim Res. 2020 ;36:32. Epub 2020 Sep 17. PMID:
32983956
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baicalin ameliorates cognitive impairment and protects microglia from LPS-induced neuroinflammation.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2020 ;2020:4751349. Epub 2020 Sep 22. PMID:
33029280
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baicalin liposome alleviates lipopolysaccharide-induced acute lung injury.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2020 ;2020:8414062. Epub 2020 Nov 11. PMID:
33223957
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Barley sprouts have a protective effect against alcohol-induced liver injury.
Jul 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Jul 21 ;8(7). Epub 2016 Jul 21. PMID:
27455313
Article Published Date
: Jul 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Barley
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Bay leaf contains compounds which inhibit LPS-activated nitric oxide production and which induce heat shock protein.
Apr 21, 2000
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2000 Apr 21;66(22):2151-7. PMID:
10834299
Article Published Date
: Apr 21, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Bay leaf
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Enzyme Inhibitors
,
Heat Shock Protein Inducer
,
Nitric Oxide Inhibitor
[+]
Bee venom soluble phospholipase A2 exerts neuroprotective effects in a lipopolysaccharide-induced mouse model of Alzheimer's disease.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Aging Neurosci. 2019 ;11:287. Epub 2019 Nov 1. PMID:
31736738
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Alzheimer's Disease
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Beneficial effects of tea water extracts on the body weight and gut microbiota in C57BL/6J mice fed with a high-fat diet.
May 06, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 May 7. Epub 2019 May 7. PMID:
31062778
Article Published Date
: May 06, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Green Tea
Diseases
:
High Fat Diet
,
Lipopolysaccharide-Induced Toxicity
,
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Berberine alleviates endothelial glycocalyx degradation and promotes glycocalyx restoration in LPS-induced ARDS.
Oct 07, 2018
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2018 Oct 8 ;65:96-107. Epub 2018 Oct 8. PMID:
30308440
Article Published Date
: Oct 07, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Acute Respiratory Distress Syndrome
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine can be a potential therapeutic agent for osteoclast-related bone diseases.
Mar 03, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2019 Mar 4:1-17. Epub 2019 Mar 4. PMID:
30827151
Article Published Date
: Mar 03, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Bone Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Osteoprotective
[+]
Berberine can improve myocardial injury and cardiac function in sepsis.
Sep 21, 2020
Click here to read the entire abstract
Pubmed Data
: Zhonghua Yi Xue Za Zhi. 2020 Sep 22 ;100(35):2779-2784. PMID:
32972060
Article Published Date
: Sep 21, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Cardiomyopathy
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine functions as a negative regulator in lipopolysaccharide -induced sepsis.
Oct 06, 2020
Click here to read the entire abstract
Pubmed Data
: Pathog Dis. 2020 Oct 7 ;78(7). PMID:
32857851
Article Published Date
: Oct 06, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine hydrochloride can provide mice robust protection from LPS-induced mastitis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:5164314. Epub 2018 Apr 15. PMID:
29849710
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Mastitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2020 ;15(5):e0232630. Epub 2020 May 1. PMID:
32357187
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Beta glucan inhibits experimental periodontal disease possibly through steering the T helper Th1/Th2 balance towards Th1 and T regulatory responses.
Apr 01, 2005
Click here to read the entire abstract
Pubmed Data
: J Clin Periodontol. 2005 Apr;32(4):347-52. PMID:
15811050
Article Published Date
: Apr 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Beta-glucan
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance
,
Lipopolysaccharide-Induced Toxicity
,
Periodontal Diseases
Pharmacological Actions
:
Immunomodulatory
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Biochanin A exerts protective effects on lipopolysaccharide-induced Parkinson's disease.
Jan 09, 2016
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2016 10 ;30(3):486-98. Epub 2016 Jul 14. PMID:
27417698
Article Published Date
: Jan 09, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Biochanin A protect against lipopolysaccharide-induced acute lung injury.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Microb Pathog. 2020 Jan ;138:103846. Epub 2019 Nov 4. PMID:
31698051
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Sep ;38:324-31. Epub 2016 Jun 23. PMID:
27344638
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bisdemethoxycurcumin attenuates lipopolysaccharide-induced intestinal damag.
Oct 18, 2021
Click here to read the entire abstract
Pubmed Data
: J Anim Sci. 2021 Oct 19. Epub 2021 Oct 19. PMID:
34664650
Article Published Date
: Oct 18, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Bisdemethoxycurcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastroprotective
[+]
Bisdemethoxycurcumin protects small intestine from lipopolysaccharide-induced mitochondrial dysfunction.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2021 ;2021:9927864. Epub 2021 Nov 9. PMID:
34795844
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Bisdemethoxycurcumin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Mitochondrial Dysfunction
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
[+]
Black Adzuki bean attenuates high-fat diet-induced colon inflammation.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2017 Apr ;20(4):367-375. PMID:
28406732
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Aduki bean
Diseases
:
Colitis
,
High Fat Diet
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Black ginseng extract suppresses airway inflammation induced by cigarette smoke and lipopolysaccharides.
Mar 29, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2022 Mar 30 ;11(4). Epub 2022 Mar 30. PMID:
35453364
Article Published Date
: Mar 29, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Smoking
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Brazilian propolis contains some natural products that can decrease thrombotic tendencies in mice.
Aug 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Intercult Ethnopharmacol. 2016 Sep-Dec;5(4):439-443. Epub 2016 Aug 17. PMID:
27757277
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Brazillian
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-thrombotic
[+]
Buckwheat sprouts have an anti-inflammatory effect in lipopolysaccharide-activated human colon cancer cells and mice.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2008 Dec;72(12):3148-57. Epub 2008 Dec 7. PMID:
19060399
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Buckwheat
,
Flavonoids
,
Sprouts
Diseases
:
Colon Cancer
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Butyrate and dietary soluble fiber improves neuroinflammation associated with aging.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Immunol. 2018 ;9:1832. Epub 2018 Aug 14. PMID:
30154787
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Butyrate
,
Fiber
Diseases
:
Aging
,
Brain Inflammation
,
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Epigenetic Modification
[+]
By promoting fertility and eliminating oxidative stress and inflammation, Punicalagin may be a useful nutrient for the treatment of infertility.
Jan 11, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian J Androl. 2016 Jan 12. Epub 2016 Jan 12. PMID:
26763544
Article Published Date
: Jan 11, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Infertility: Male
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Fertility Agents
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
C. obtusa essential oil may constitute a novel source of anti-inflammatory treatments.
Jun 30, 2013
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2013 Jul ;8(1):255-9. Epub 2013 May 8. PMID:
23652412
Article Published Date
: Jun 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Japanese cypress
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Oils
[+]
Caffeine may abrogate lipopolysaccharide-induced oxidative stress and neuroinflammation.
Nov 07, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomolecules. 2019 Nov 8 ;9(11). Epub 2019 Nov 8. PMID:
31717470
Article Published Date
: Nov 07, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Caffeine
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Cannabidiol antidepressant-like effect in the lipopolysaccharide model in mice: modulation of inflammatory pathways.
Jan 25, 2021
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2021 Jan 26:114433. Epub 2021 Jan 26. PMID:
33513342
Article Published Date
: Jan 25, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-6 Downregulation
[+]
Cannabidiol has a neuroprotective effect in endotoxin-induced uveitis.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Mol Vis. 2008;14:2190-203. Epub 2008 Dec 3. PMID:
19052649
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Brain: Microglial Activation
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Uveitis
Pharmacological Actions
:
Enzyme Inhibitors
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.
Aug 14, 2000
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Proc Natl Acad Sci U S A. 2000 Aug 15 ;97(17):9561-6. PMID:
10920191
Article Published Date
: Aug 14, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Arthritis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunosuppressive Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol might become a useful therapeutic tool for the attenuation and treatment of inflammatory lung diseases.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2015 Feb ;37(1):35-41. Epub 2014 Oct 30. PMID:
25356537
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Interstitial Lung Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabinoids may have therapeutic value in neurodegenerative conditions by preventing and/or reducing neuroinflammation.
Feb 22, 2007
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2007 Feb 23 ;144(4):1516-22. Epub 2006 Dec 18. PMID:
17178196
Article Published Date
: Feb 22, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Capsaicin protects against lipopolysaccharide-induced acute lung injury.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Inflamm Res. 2021 ;14:5291-5304. Epub 2021 Oct 14. PMID:
34703269
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Capsaicin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
[+]
Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome.
Jun 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Pharm Sin B. 2019 Jul ;9(4):734-744. Epub 2019 Feb 14. PMID:
31384534
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cardamonin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Septic Shock
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Carnosic acid protects against lipopolysaccharide-induced acute lung injury in mice.
Oct 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2019 Nov ;18(5):3707-3714. Epub 2019 Sep 23. PMID:
31611929
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Carvacrol has significant potential as an inhibitor of memory degeneration in neurodegenerative diseases.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2020 Jan ;24(1):27-37. Epub 2020 Dec 20. PMID:
31908572
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
[+]
Carvacrol prevents the proconvulsant effect of LPS possibly through the inhibition of the COX-2 increased activity.
Jan 11, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2018 12 ;33(6):2045-2050. Epub 2018 Sep 18. PMID:
30229386
Article Published Date
: Jan 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Seizures
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Celastrol inhibits microglial pyroptosis and attenuates inflammatory reaction in acute spinal cord injury rats.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2019 Jan ;66:215-223. Epub 2018 Nov 22. PMID:
30472522
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Celastrol
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect.
Jan 19, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mil Med Res. 2022 05 20 ;9(1):22. Epub 2022 May 20. PMID:
35596191
Article Published Date
: Jan 19, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Celastrol
Diseases
:
Endotoxemia
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Cell wall contents of probiotics protect against lipopolysaccharide-induced murine colitis.
Feb 04, 2021
Click here to read the entire abstract
Pubmed Data
: Probiotics Antimicrob Proteins. 2021 Feb 5. Epub 2021 Feb 5. PMID:
33544362
Article Published Date
: Feb 04, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Probiotics
Diseases
:
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Centella asiantica has a protective effect against acute liver injury in mice.
Feb 17, 2010
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2010 Feb 17. Epub 2010 Feb 17. PMID:
20171071
Article Published Date
: Feb 17, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Centella asiatica
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Chicoric acid alleviates lipopolysaccharide-induced acute lung injury.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2019 Jan ;66:169-176. Epub 2018 Nov 19. PMID:
30466029
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Chicoric Acid
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Chicoric acid ameliorate inflammation and oxidative stress in Lipopolysaccharide and d-galactosamine induced acute liver injury.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2020 03 ;24(5):3022-3033. Epub 2020 Jan 27. PMID:
31989756
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chicoric Acid
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Chilean white strawberry aqueous extract favours the normalization of oxidative and inflammatory responses after a liver injury induced by LPS.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:320136. Epub 2015 Sep 17. PMID:
26457108
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Strawberry
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chronic consumption of γ-oryzanol can revert the LPS-induced cognitive and memory impairments by promoting hippocampal antioxidant and anti-inflammatory molecular responses.
Mar 29, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Mar 29 ;11(4). Epub 2019 Mar 29. PMID:
30934852
Article Published Date
: Mar 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gamma-Oryzanol
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation.
Aug 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Neurochem. 2007 Aug;102(3):761-72. Epub 2007 May 4. PMID:
17488274
Article Published Date
: Aug 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Lithium
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Chrysanthemum indicum has a protective effect on acute lung injury induced by lipopolysaccharide.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2014 ;2014:246407. Epub 2014 Aug 25. PMID:
25214712
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chrysin alleviates lipopolysaccharide-induced neuron damage and behavioral deficits in mice through inhibition of Fyn.
Sep 30, 2022
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2022 Oct ;111:109118. Epub 2022 Aug 10. PMID:
35963156
Article Published Date
: Sep 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Neuroprotective Agents
[+]
Chrysin prevents lipopolysaccharide-induced acute lung injury.
Mar 23, 2021
Click here to read the entire abstract
Pubmed Data
: Pulm Pharmacol Ther. 2021 Mar 24 ;68:102018. Epub 2021 Mar 24. PMID:
33771723
Article Published Date
: Mar 23, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Cigarette smoke exposure combined with lipopolysaccharides induced pulmonary fibrosis in mice.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Respir Physiol Neurobiol. 2019 Aug ;266:9-17. Epub 2019 Apr 22. PMID:
31022471
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Pulmonary Fibrosis
Problem Substances
:
Electronic Cigarettes
[+]
Cinnamon oil and eucalyptus oil exhibited wide antioxidant and anti-inflammatory activities against LPS-induced inflammation.
Dec 05, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2021 Dec 6 ;26(23). Epub 2021 Dec 6. PMID:
34885991
Article Published Date
: Dec 05, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cinnamon
,
Eucalyptus
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Clorpyrifos significantly altered the gut microbiota composition.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Chemosphere. 2016 Jun ;153:287-93. Epub 2016 Mar 26. PMID:
27018521
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
,
Pesticide Toxicity
Additional Keywords
:
Microbiota
Problem Substances
:
Chlorpyrifos
,
Pesticides
[+]
Comparative study on anti-inflammatory effect of Lonicerae Japonicae Flos and Lonicerae Flos.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2020 Aug ;45(16):3938-3944. PMID:
32893592
Article Published Date
: Jul 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Honeysuckle
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Constituents of Moringa oleifera seeds regulate expression of Th17-relevant cytokines and ameliorate TPA-induced psoriasis-like skin lesions.
Dec 09, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2018 Dec 10 ;23(12). Epub 2018 Dec 10. PMID:
30544700
Article Published Date
: Dec 09, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-12 downregulation
,
Interleukin-23 Downregulation
Additional Keywords
:
Plant Extracts
[+]
CoQ10 supplementation reduces broiler chickens' susceptibility to ascites through improving mitochondrial function.
Sep 01, 2003
Click here to read the entire abstract
Pubmed Data
: Angiology. 2003 Sep-Oct;54(5):531-9. PMID:
16359119
Article Published Date
: Sep 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Ascites
,
Lipopolysaccharide-Induced Toxicity
[+]
Cordycepin alleviated metabolic inflammation in Western diet.
Mar 31, 2022
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2022 Apr ;178:106191. Epub 2022 Mar 25. PMID:
35346845
Article Published Date
: Mar 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps Militaris
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
Additional Keywords
:
Anti-Obesity Agents
Anti Therapeutic Actions
:
Western Diet
[+]
Cordycepin inhibits inflammatory responses through suppression of ERK activation in zebrafish.
Jun 18, 2021
Click here to read the entire abstract
Pubmed Data
: Dev Comp Immunol. 2021 Jun 19 ;124:104178. Epub 2021 Jun 19. PMID:
34157317
Article Published Date
: Jun 18, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps Militaris
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
[+]
Cordyceps suppresses the expression of diabetes regulating genes by inhibiting lipopolysaccharide-induced inflammation in macrophages.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Immune Netw. 2009 Jun;9(3):98-105. Epub 2009 Jun 30. PMID:
20107539
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps sinensis
Diseases
:
Diabetes Mellitus: Type 2
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Corn silk extract ameliorated lipopolysaccharide-induced inflammation in mice.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Feb 1 ;65(4):759-768. Epub 2017 Jan 17. PMID:
28064493
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Corn Silk
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Corylin ameliorates lipopolysaccharide-induced acute lung injury.
Oct 13, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceuticals (Basel). 2021 Oct 14 ;14(10). Epub 2021 Oct 14. PMID:
34681270
Article Published Date
: Oct 13, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Babchi
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Crocetin may be used as a novel therapy for preventing fulminant hepatic failure.
Oct 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2019 Nov ;18(5):3775-3782. Epub 2019 Sep 19. PMID:
31616509
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Crocetin
Diseases
:
Fulminant Hepatic Failure
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Crocin alleviates lipopolysaccharide-induced acute respiratory distress syndrome.
Jan 09, 2020
Click here to read the entire abstract
Pubmed Data
: Inflamm Res. 2020 Jan 10. Epub 2020 Jan 10. PMID:
31925528
Article Published Date
: Jan 09, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Crocin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Respiratory Distress Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Crocus sativus, Serenoa repens and Pinus massoniana extracts modulate inflammatory response in isolated rat prostate challenged with LPS.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: J Biol Regul Homeost Agents. 2017 Jul-Sep,;31(3):531-541. PMID:
28889734
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pine Bark Extract
,
Saffron
,
Saw Palmetto
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Curcumin administration could be used as supplementary therapeutic intervention at early stage of endotoxemia.
Mar 12, 2017
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2017 Mar 13. Epub 2017 Mar 13. PMID:
28289922
Article Published Date
: Mar 12, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin alleviated lung edema in lipopolysaccharide induced acute lung injury by inhibiting inflammation.
Feb 25, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Sci Monit. 2018 Feb 26 ;24:1178-1184. Epub 2018 Feb 26. PMID:
29480285
Article Published Date
: Feb 25, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Curcumin ameliorates endotoxin-induced experimental hepatoxicity in rodents.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: Clin Exp Immunol. 2006 Aug;145(2):313-21. PMID:
16879252
Article Published Date
: Aug 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin and selenium can hinder the progression and severity of liver injury during acute inflammatory episodes.
Oct 24, 2019
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2019 Oct 25. Epub 2019 Oct 25. PMID:
31654258
Article Published Date
: Oct 24, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Selenium
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Diclofenac
[+]
Curcumin attenuates lipopolysaccharide-induced renal inflammation.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: Biol Pharm Bull. 2011;34(2):226-32. PMID:
21415532
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Inflammatory Kidney Diseases
,
Kidney Infection
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Renoprotective
[+]
Curcumin attenuates LPS-induced sickness behavior.
May 10, 2022
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2022 May 11 ;781:136680. Epub 2022 May 11. PMID:
35568344
Article Published Date
: May 10, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
Curcumin compares favorably with bisdemethoxycurcumin in a gastric ulcer model system.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2009 Apr;16(4):342-51. Epub 2009 Feb 1. PMID:
19188055
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Bisdemethoxycurcumin
,
Curcumin
Diseases
:
Gastric Ulcer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Ulcer Agents
,
Proton Pump Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin has a neuroprotective effect on focal cerebral ischemic rats by preventing blood-brain barrier damage.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Chemotherapy. 2010;56(1):60-5. Epub 2010 Mar 19. PMID:
17303117
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Blood-Brain-Barrier Disorders
,
Brain Ischemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin inhibits liver injury in a mouse model of endotoxemic shock.
Feb 01, 2010
Click here to read the entire abstract
Pubmed Data
: Biotechnol Lett. 2010 Feb;32(2):209-14. Epub 2009 Oct 25. PMID:
19856147
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits.
Sep 28, 2008
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2008 Sep 28;593(1-3):105-11. Epub 2008 Jul 15. PMID:
18664365
Article Published Date
: Sep 28, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Fever
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-pyretic
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin modulates the immune response associated with LPS-induced periodontal disease in rats, indicating its potential therapeutic value.
Jan 17, 2011
Click here to read the entire abstract
Pubmed Data
: Innate Immun. 2011 Jan 17. Epub 2011 Jan 17. PMID:
21242275
Article Published Date
: Jan 17, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Periodontal Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Curcumin protects against experimental liver injury in mice.
Aug 01, 2003
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2003 Aug;28(8):756-8, 793. PMID:
15015361
Article Published Date
: Aug 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin protects pre-oligodendrocytes from activated microglia, indicating it may play a role in protecting against preterm periventricular leukomalacia (PVL).
Jun 21, 2010
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2010 Jun 21;1339:60-9. Epub 2010 Apr 24. PMID:
20403340
Article Published Date
: Jun 21, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Preterm Periventricular Leukomalacia (PVL)
Pharmacological Actions
:
Apoptotic
,
Enzyme Inhibitors
,
Neuroprotective Agents
[+]
Curcumin reduces nitric oxide formation and associated inflammation in the rat mammary gland.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Exp Biol. 2009 Jan;212(Pt 2):163-8. PMID:
11020339
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antineoplastic Agents
,
Antioxidants
,
Nitric Oxide Inhibitor
[+]
Curcumin treatment attenuates lipopolysaccharide induced liver injury.
Jul 05, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Jul 6 ;83:302-313. Epub 2016 Jul 6. PMID:
27393927
Article Published Date
: Jul 05, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Dandelion protects against lipopolysaccharide-induced acute lung injury in mice.
Jul 20, 2010
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2010 Jul 20;130(2):392-7. Epub 2010 May 25. PMID:
20510343
Article Published Date
: Jul 20, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Diallyl disulfide administration prevents and reveres lipopolysaccharide-induced depression-like behaviours.
Jul 31, 2021
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2021 Aug ;44(4):1381-1395. Epub 2021 Jan 29. PMID:
33511484
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Brain Inflammation
,
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Antioxidants
[+]
Diallyl sulfide protects against lipopolysaccharide/d-galactosamine-induced acute liver injury.
Jul 30, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Jul 31 ;120:500-509. Epub 2018 Jul 31. PMID:
30075314
Article Published Date
: Jul 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Diallyl sulfide
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary addition of flaxseed oil enhances intestinal integrity and barrier function.
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2018 May ;62(9):e1700814. Epub 2018 Apr 14. PMID:
29510469
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed Oil
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastroprotective
[+]
Dietary arginine supplementation alleviates intestinal mucosal disruption induced by Escherichia coli lipopolysaccharide in weaned pigs.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2008 Sep;100(3):552-60. Epub 2008 Feb 14. PMID:
18275628
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Arginine
Diseases
:
Escherichia coli Infections
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary bisdemethoxycurcumin supplementation attenuates lipopolysaccharide-induced damages on intestinal redox potential.
Apr 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Poult Sci. 2021 May ;100(5):101061. Epub 2021 Feb 19. PMID:
33756250
Article Published Date
: Apr 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Bisdemethoxycurcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Antioxidants
[+]
Dietary histidine ameliorates mouse colitis through the inhibition of proinflammatory cytokine production from macrophages.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Gastroenterology. 2009 Feb;136(2):564-74.e2. Epub 2008 Oct 7. PMID:
19027739
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Histidine
Diseases
:
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary intake of ascorbic acid attenuates lipopolysaccharide-induced sepsis and septic inflammation.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Nutr Sci Vitaminol (Tokyo). 2018 ;64(6):404-411. PMID:
30606963
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
dietary L. casei alleviates LPS-induced liver injury via reducing pro-inflammatory cytokines and increasing anti-oxidative capacity.
Nov 25, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Nov 26 ;18(12). Epub 2017 Nov 26. PMID:
29186870
Article Published Date
: Nov 25, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus casei
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress caused by lipopolysaccharide.
Dec 10, 2019
Click here to read the entire abstract
Pubmed Data
: J Anim Sci. 2019 Dec 11. Epub 2019 Dec 11. PMID:
31822918
Article Published Date
: Dec 10, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pterostilbene
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastroprotective
[+]
Diosgenin attenuates lipopolysaccharide-induced Parkinson's disease.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2018 ;64(3):943-955. PMID:
29966203
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Diosgenin suppresses COX-2 and mPGES-1 via GR and improves LPS-induced liver injury.
Jan 09, 2021
Click here to read the entire abstract
Pubmed Data
: Prostaglandins Other Lipid Mediat. 2021 10 ;156:106580. Epub 2021 Jul 9. PMID:
34252545
Article Published Date
: Jan 09, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Prostaglandin E Synthase-1 (PGES-1) Down-Regulation
[+]
Diosmetin inhibits osteoclast formation and differentiation and prevents LPS-induced osteolysis in mice.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Cell Physiol. 2019 Aug ;234(8):12701-12713. Epub 2018 Dec 4. PMID:
30515812
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Diosmetin
Diseases
:
Bone Diseases: Over-Active Osteoclasts
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Osteoprotective
[+]
Diosmin is a promising molecule for the treatment of inflammation and pain.
Feb 20, 2020
Click here to read the entire abstract
Pubmed Data
: J Nat Prod. 2020 Feb 21. Epub 2020 Feb 21. PMID:
32083866
Article Published Date
: Feb 20, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Echinacea polysaccharide attenuates lipopolysaccharide‑induced acute kidney injury.
Oct 22, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2020 Oct 23. Epub 2020 Oct 23. PMID:
33416087
Article Published Date
: Oct 22, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Echinacea
Diseases
:
Kidney Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Echinacea reduces Candida albicans associated mortality in mice.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2006;47 Suppl 2:S177-86; discussion S206-9. PMID:
15949903
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Echinacea
Diseases
:
Candida Infection
,
Immune Disorders: Low Immune Function
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Immunostimulatory
Additional Keywords
:
Plant Extracts
[+]
Effect of blueberry (Vaccinium virgatum) extract on depressive-like behavior and metabolic serum alterations.
Jan 09, 2021
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2021 10 ;45(10):e13920. Epub 2021 Sep 12. PMID:
34510463
Article Published Date
: Jan 09, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Plant Extracts
[+]
Effects of crocin on spatial or aversive learning and memory impairments induced by lipopolysaccharide.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Avicenna J Phytomed. 2021 Jan-Feb;11(1):79-90. PMID:
33628722
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Learning disorders
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Effects of Salvia miltiorrhiza Bunge extract and its single components on monosodium urate-induced pain.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Tradit Chin Med. 2021 04 ;41(2):219-226. PMID:
33825401
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Salvia miltiorrhiza
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
Efficacy of a standardized turmeric extract comprised of 70% bisdemothoxy-curcumin against LPS-induced inflammation.
Dec 31, 2020
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Article Publish Status
: This is a free article.
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Pubmed Data
: J Inflamm Res. 2021 ;14:859-868. Epub 2021 Mar 12. PMID:
33737826
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Turmeric
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
EGCG has a beneficial effect on impaired adult neurogenesis caused by lipopolysaccharide induced neuro-inflammation.
Dec 31, 2015
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Article Publish Status
: This is a free article.
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Pubmed Data
: Korean J Physiol Pharmacol. 2016 Jan ;20(1):41-51. Epub 2015 Dec 31. PMID:
26807022
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
EGCG promotes PRKCA expression to alleviate LPS-induced acute lung injury and inflammatory response.
May 25, 2021
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Article Publish Status
: This is a free article.
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Pubmed Data
: Sci Rep. 2021 May 26 ;11(1):11014. Epub 2021 May 26. PMID:
34040072
Article Published Date
: May 25, 2021
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Infection
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Electroacupuncture pretreatment exhibits lung protective and anti-Inflammation effects in lipopolysaccharide-induced acute lung injury.
Dec 31, 2021
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Pubmed Data
: Evid Based Complement Alternat Med. 2022 ;2022:2252218. Epub 2022 Mar 15. PMID:
35341153
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Electroacupuncture relieves hippocampal injury by heme oxygenase-1 to improve mitochondrial function.
Dec 31, 2021
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Pubmed Data
: J Surg Res. 2022 05 ;273:15-23. Epub 2022 Jan 10. PMID:
35016152
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Sepsis
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
[+]
Ellagic acid inhibits neuroinflammation and cognitive impairment induced by lipopolysaccharides.
Aug 09, 2020
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Pubmed Data
: Neurochem Res. 2020 Aug 10. Epub 2020 Aug 10. PMID:
32779097
Article Published Date
: Aug 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ellagic acid protects lipopolysaccharide/D-galactosamine-induced acute hepatic injury.
Sep 30, 2014
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Pubmed Data
: Int Immunopharmacol. 2014 Oct ;22(2):341-5. Epub 2014 Jul 16. PMID:
25038320
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 inducer
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Embelia ribes ameliorates lipopolysaccharide-induced acute respiratory distress syndrome.
Jun 19, 2015
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Pubmed Data
: J Ethnopharmacol. 2015 Jun 20 ;168:356-63. Epub 2015 Mar 27. PMID:
25818695
Article Published Date
: Jun 19, 2015
Study Type
: Animal Study
Additional Links
Substances
:
False Black Pepper
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Respiratory Distress Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
[+]
Emodin alleviated LPS-induced pulmonary inflammation in rat lung tissues.
Mar 31, 2020
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Pubmed Data
: Inflamm Res. 2020 Apr ;69(4):365-373. Epub 2020 Mar 4. PMID:
32130427
Article Published Date
: Mar 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Emodin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Emodin alleviates LPS-induced myocardial injury through inhibition of NLRP3 inflammasome activation.
Jun 15, 2021
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Pubmed Data
: Phytother Res. 2021 Jun 16. Epub 2021 Jun 16. PMID:
34131970
Article Published Date
: Jun 15, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Emodin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
[+]
Emodin attenuates LPS-induced acute lung injury.
Nov 16, 2021
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Inflammation. 2021 Nov 17. Epub 2021 Nov 17. PMID:
34787801
Article Published Date
: Nov 16, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Emodin
