Liver Cancer: Prevention

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40 Substances Researched for Liver Cancer: Prevention
NameACCKFocus
Green Tea360Locked
Coffee240Locked
Tea120Locked
beta-Carotene314Locked
Fish110Locked
Linoleic acid110Locked
Phyllanthus urinaria110Locked
Anthocyanins27Locked
Flavonoids27Locked
Ginger36Locked
Quercetin46Locked
Curcumin35Locked
Resveratrol35Locked
Garlic24Locked
EGCG (Epigallocatechin gallate)23Locked
Allicin12Locked
Alpha-Carotene12Locked
Asparagus12Locked
Black Tea12Locked
Black Tea Theaflavins12Locked
Cabbage12Locked
Carotenoids12Locked
Chlorophyll12Locked
Geraniol 12Locked
Ginkgo biloba12Locked
Piperine12Locked
Reishi Mushroom12Locked
Rice Bran12Locked
Spinach12Locked
Theaflavins12Locked
Vitamin A12Locked
White Mulberry 12Locked
Hesperidin11Locked
Lignans11Locked
Lutein11Locked
Lycopene11Locked
Rutin11Locked
Sesame Seeds11Locked
Sesamin11Locked
Sulforaphane11Locked
2 Problem Substances Researched for Liver Cancer: Prevention
NameACCKFocus
Aflatoxin110Locked
N-nitrosodiethylamine12Locked
Related Topics

Liver Cancer: Prevention is a Sub of the following Topic

View the Evidence:
41 Abstracts with Liver Cancer: Prevention Research

[+]

An increased consumption of coffee may reduce the risk of liver cancer.May 01, 2007

Pubmed Data : Gastroenterology. 2007 May ;132(5):1740-5. Epub 2007 Mar 24. PMID: 17484871
Article Published Date : May 01, 2007
Study Type : Meta Analysis
Additional Links
Substances : Coffee
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

Green tea intake reduces the risk of liver disease.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Med. 2015;8(6):8339-8346. Epub 2015 Jun 15. PMID: 26309486
Article Published Date : Dec 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Green Tea
Diseases : Liver Cancer: Prevention, Liver Cirrhosis, Liver Diseases, Liver Steatosis
Pharmacological Actions : Anticarcinogenic Agents, Hepatoprotective
Additional Keywords : Risk Reduction
[+]

Increasing green tea intake may have a preventive effect against liver cancer.Jan 16, 2017

Pubmed Data : Nutr Cancer. 2017 Jan 17:1-10. Epub 2017 Jan 17. PMID: 28095030
Article Published Date : Jan 16, 2017
Study Type : Meta Analysis
Additional Links
Substances : Green Tea
Diseases : Liver Cancer, Liver Cancer: Prevention
Additional Keywords : Risk Reduction
[+]

Tea consumption has a protective effect against the development of primary liver cancer. May 01, 2011

Pubmed Data : Eur J Cancer Prev. 2011 May ;20(3):157-65. PMID: 21403523
Article Published Date : May 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Tea
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive
[+]

The present analysis indicated the preventive effects of green tea intake on the risk for liver cancer in female Asian populations.Jul 01, 2015

Pubmed Data : Nutrition. 2015 Jul 2. Epub 2015 Jul 2. PMID: 26412579
Article Published Date : Jul 01, 2015
Study Type : Meta Analysis
Additional Links
Substances : Green Tea
Diseases : Liver Cancer: Prevention
Additional Keywords : Risk Reduction
[+]

There is an inverse relationship between coffee drinking and hepatocellular carcinoma risk.Aug 01, 2007

Pubmed Data : Hepatology. 2007 Aug ;46(2):430-5. PMID: 17580359
Article Published Date : Aug 01, 2007
Study Type : Meta Analysis
Additional Links
Substances : Coffee
Diseases : Liver Cancer: Prevention
Additional Keywords : Risk Reduction
[+]

A diet rich in linoleic acid containing foods (e.g. white meats and fish) and beta-carotene was inversely related to HCC risk; iron intake was associated with increased risk. Nov 01, 2007

Pubmed Data : Eur J Cancer. 2007 Nov ;43(16):2381-7. Epub 2007 Aug 23. PMID: 17719221
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Substances : beta-Carotene, Fish, Linoleic acid
Diseases : Liver Cancer: Prevention
[+]

Aflatoxin B1 exposure increases the risk for primary liver cancer in north Indian population.Oct 01, 2011

Pubmed Data : Clin Biochem. 2011 Oct ;44(14-15):1235-40. Epub 2011 Aug 10. PMID: 21854762
Article Published Date : Oct 01, 2011
Study Type : Human Study
Additional Links
Diseases : Liver Cancer, Liver Cancer: Prevention
Problem Substances : Aflatoxin
Adverse Pharmacological Actions : Carcinogenic
[+]

Phyllanthus Urinaria is useful in preventing or delaying the development of HBV-associated cirrhosis to hepatocellular carcinoma.Mar 24, 2013

Pubmed Data : Chin J Integr Med. 2013 Mar 25. Epub 2013 Mar 25. PMID: 23529834
Article Published Date : Mar 24, 2013
Study Type : Human Study
Additional Links
Substances : Phyllanthus urinaria
Diseases : Liver Cancer: Hepatitis B Associated, Liver Cancer: Prevention, Liver Cirrhosis, Liver Damage
Pharmacological Actions : Chemopreventive
Additional Keywords : Significant Treatment Outcome
[+]

Resveratrol has a chemoprevention effect in chemically-Induced hepatocarcinogenesis.Apr 05, 2011

Pubmed Data : Curr Pharm Biotechnol. 2011 Apr 5. Epub 2011 Apr 5. PMID: 21466437
Article Published Date : Apr 05, 2011
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive
[+]

"Aged garlic extract inhibits development of putative preneoplastic lesions in rat hepatocarcinogenesis."Mar 01, 2006

Pubmed Data : J Nutr. 2006 Mar ;136(3 Suppl):855S-860S. PMID: 16484580
Article Published Date : Mar 01, 2006
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive
Additional Keywords : Plant Extracts
[+]

"Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats."Feb 15, 2011

Pubmed Data : Toxicol Appl Pharmacol. 2011 Feb 15 ;251(1):85-94. Epub 2010 Dec 15. PMID: 21167192
Article Published Date : Feb 15, 2011
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Cyclooxygenase 2 Inhibitors, Tumor Suppressor Protein p53 Upregulation
[+]

"Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats."Dec 01, 2008

Pubmed Data : Clinics (Sao Paulo). 2008 Dec ;63(6):807-13. PMID: 19061005
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

"Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model."Nov 01, 2010

Pubmed Data : Biofactors. 2010 Nov-Dec;36(6):483-90. Epub 2010 Sep 24. PMID: 20872761
Article Published Date : Nov 01, 2010
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive
Additional Keywords : Plant Extracts
[+]

"Quercetin inhibits diethylnitrosamine-induced hepatic preneoplastic lesions in rats."Jan 01, 2011

Pubmed Data : Nutr Cancer. 2011 ;63(2):234-41. PMID: 21302176
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Chemical: Lindane
[+]

A water extract of the roots of Asparagus racemosus has a preventive effect on chemically-induced hepatocarcinogenesis.Sep 01, 2008

Pubmed Data : Phytother Res. 2008 Sep ;22(9):1175-82. PMID: 18729252
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Asparagus
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive, Malondialdehyde Down-regulation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Plant Extracts
[+]

Beta-carotene and vitamin A inhibit hepatocarcinogenesis.Jan 01, 2002

Pubmed Data : Nutr Cancer. 2002 ;44(1):80-8. PMID: 12672634
Article Published Date : Jan 01, 2002
Study Type : Animal Study
Additional Links
Substances : beta-Carotene, Vitamin A
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Antioxidants, Antiproliferative , Chemopreventive
[+]

Chinese cabbage powder effectively reduced the incidence of liver tumour induced by aflatoxin B1 from 6.67% to 0% in animals. Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem. 2015 Nov 1 ;186:13-9. Epub 2015 Mar 6. PMID: 25976785
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Cabbage
Diseases : Liver Cancer: Prevention, Liver Damage: Aflatoxin-Induced
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Risk Reduction
[+]

Curcumin in combination with piperine shows better suppression of DENA-induced hepatocellular carcinoma in contrast to curcumin on its own. Jul 25, 2015

Pubmed Data : Environ Toxicol Pharmacol. 2015 Jul 26 ;40(2):445-452. Epub 2015 Jul 26. PMID: 26278679
Article Published Date : Jul 25, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin, Piperine
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Natural Substance Synergy
[+]

Curcumin potentiated significant increase in Nrf2 activation. It restored activity of phase-II antioxidant enzymes like GST, GR, NQO1, and tumour suppressor p53 level. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(4):e0124000. Epub 2015 Apr 10. PMID: 25860911
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Liver Cancer, Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Cyclooxygenase 2 Inhibitors, MicroRNA modulator, Nrf2 activation, Tumor Suppressor Protein p53 Upregulation
[+]

Epigallocatechin gallete and theaflavin restrict mouse liver carcinogenesis through modulation of self-renewal Wnt and hedgehog pathways.Aug 20, 2015

Pubmed Data : J Nutr Biochem. 2015 Aug 21. Epub 2015 Aug 21. PMID: 26386739
Article Published Date : Aug 20, 2015
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Theaflavins
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Wnt/β-catenin signaling pathway modulation
[+]

Ganoderma lucidum polysaccharides inhibited hepatocellular carcinoma proliferation through inhibiting miR-125b and inhibiting tregs accumulation and function.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Transl Med. 2015 ;13:100. Epub 2015 Mar 26. PMID: 25889022
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Liver Cancer, Liver Cancer: Prevention
Pharmacological Actions : Antiproliferative , Chemotherapeutic, MicroRNA modulator
[+]

Garlic powder prevents carcinogen-induced DNA damage in rat liver and colon.Jan 01, 2006

Pubmed Data : Nutr Cancer. 2006 ;55(2):178-84. PMID: 17044773
Article Published Date : Jan 01, 2006
Study Type : Animal Study
Additional Links
Substances : Allicin, Garlic
Diseases : Colon Cancer: Prevention, DNA damage, Liver Cancer: Prevention
Pharmacological Actions : Antineoplastic Agents, Chemopreventive
[+]

Geraniol is a promising compound useful for suppression of hepatocellular carcinoma. Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Yonago Acta Med. 2016 Mar ;59(1):37-43. Epub 2016 Apr 1. PMID: 27046949
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Geraniol
Diseases : Liver Cancer, Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents
[+]

Ginger (Zingiber officinale) prevents ethionine induced rat hepatocarcinogenesis.Jan 01, 2008

Pubmed Data : Afr J Tradit Complement Altern Med. 2008 ;6(1):87-93. Epub 2008 Oct 25. PMID: 20162046
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive
[+]

Ginkgo biloba has a protective effect against rat liver carcinogenesis.May 09, 2008

Pubmed Data : Chem Biol Interact. 2008 May 9 ;173(1):32-42. Epub 2008 Feb 12. PMID: 18367157
Article Published Date : May 09, 2008
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Plant Extracts
[+]

Korean red ginseng has a chemopreventive effect on chemically-induced rat hepatocarcinogenesis by suppression of oxidative stress and modulation of redox-enzymes.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer. 2015 ;6(1):1-8. Epub 2015 Jan 1. PMID: 25553083
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Liver Cancer: Prevention, Oxidative Stress
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Chemopreventive, Redox Modulator
[+]

Purple rice bran extract exhibited cancer chemopreventive effects on the aflatoxin B1induced initiation stage of hepatocarcinogenesis in ratsDec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(8):3371-6. PMID: 25921147
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Rice Bran
Diseases : Liver Cancer: Prevention, Liver Damage: Aflatoxin-Induced
Pharmacological Actions : Anticarcinogenic Agents, Genoprotective, Hepatoprotective
Additional Keywords : Xenobiotic Metabolism
[+]

Quercetin has a preventive effect on hepatic cancer in rats. Jan 01, 2009

Pubmed Data : J Exp Clin Cancer Res. 2009 ;28:80. Epub 2009 Jun 11. PMID: 19519916
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Antioxidants, Chemopreventive
[+]

Resveratrol interferes with N-nitrosodiethylamine-induced hepatocellular carcinoma at early and advanced stages in male rats.Nov 01, 2011

Pubmed Data : Mol Med Report. 2011 Nov-Dec;4(6):1211-7. Epub 2011 Aug 16. PMID: 21850372
Article Published Date : Nov 01, 2011
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Chemopreventive
[+]

Theaflavin enriched black tea extracts exhibited hepatoprotective effects on experimental fibrosis.Jun 09, 2015

Pubmed Data : Food Funct. 2015 Jun 10 ;6(6):1832-40. PMID: 25927469
Article Published Date : Jun 09, 2015
Study Type : Animal Study
Additional Links
Substances : Black Tea, Black Tea Theaflavins
Diseases : Fibrosis, Liver Cancer: Prevention, Liver Damage
Pharmacological Actions : Hepatoprotective
Additional Keywords : Risk Reduction
[+]

These results show that Chl concentrations encountered in Chl-rich green vegetables can provide substantial cancer chemoprotection, and suggest that they do so by reducing carcinogen bioavailability.Jan 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem Toxicol. 2012 Feb ;50(2):341-52. Epub 2011 Nov 3. PMID: 22079312
Article Published Date : Jan 31, 2012
Study Type : Animal Study
Additional Links
Substances : Chlorophyll, Spinach
Diseases : Cancers: All, Colon Cancer: Prevention, Colorectal Cancer: Prevention , Liver Cancer, Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Dietary Concentrations, Plant Extracts
[+]

These results suggest that not only beta-carotene, but also other types of carotenoids, such as alpha-carotene, may play an important role in cancer prevention.Nov 30, 1992

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Res. 1992 Dec 1 ;52(23):6583-7. PMID: 1423303
Article Published Date : Nov 30, 1992
Study Type : Animal Study
Additional Links
Substances : Alpha-Carotene, beta-Carotene, Carotenoids
Diseases : Liver Cancer: Prevention, Lung Cancer: Prevention, Skin Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents
[+]

Treatment with mulberry leaf extract partially protected the livers of rats from NDEA-induced hepatocarcinogenesis.Jan 10, 2016

Pubmed Data : In Vivo. 2016 11-12;30(6):807-812. PMID: 27815465
Article Published Date : Jan 10, 2016
Study Type : Animal Study
Additional Links
Substances : White Mulberry
Diseases : Liver Cancer, Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Plant Extracts
Problem Substances : N-nitrosodiethylamine
[+]

Hesperidin could be proposed as a candidate molecule in chemoprevention in epigenetic therapy purposes.Jan 26, 2017

Pubmed Data : Mol Carcinog. 2017 Jan 27. Epub 2017 Jan 27. PMID: 28130850
Article Published Date : Jan 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin
Diseases : Liver Cancer: Prevention, Promyelocytic leukemia
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Epigenetic Modification In Cancer
[+]

Lutein and lycopene exhibit chemopreventive properties during hepatocarcinogenesis.Jan 01, 2003

Pubmed Data : Nutr Cancer. 2003 ;47(1):62-9. PMID: 14769539
Article Published Date : Jan 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Lutein, Lycopene
Diseases : Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents
[+]

Numerous nutrients and non-nutrient dietary bioactive components can reduce the occurrence and delay the development of liver cancer. Jun 07, 2016

Pubmed Data : Nutr Cancer. 2016 Jun 8:1-15. Epub 2016 Jun 8. PMID: 27266713
Article Published Date : Jun 07, 2016
Study Type : Review
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Resveratrol, Sulforaphane
Diseases : Liver Cancer, Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Epigenetic Modification In Cancer
[+]

Quercetin elicited anticarcinogenic action by upregulation of p53 and BAX in HepG2 cells via downregulation of ROS, PKC, PI3K and COX-2.Aug 26, 2015

Pubmed Data : Mol Biol Rep. 2015 Aug 27. Epub 2015 Aug 27. PMID: 26311153
Article Published Date : Aug 26, 2015
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Liver Cancer, Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Tumor Suppressor Protein p53 Upregulation
[+]

Quercetin inhibits benzo[a]pyrene-induced DNA adducts in human liver cells.Jan 01, 1999

Pubmed Data : Nutr Cancer. 1999 ;35(2):175-9. PMID: 10693172
Article Published Date : Jan 01, 1999
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Benzo[a]pyrene-induced Toxicity , DNA damage, Liver Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

Rutin exhbits a protective effect against chemically-induced liver cancer. Jul 01, 2011

Pubmed Data : Exp Toxicol Pathol. 2011 Jul ;63(5):459-65. Epub 2010 Apr 17. PMID: 20399630
Article Published Date : Jul 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Rutin
Diseases : Benzo[a]pyrene-induced Toxicity , DNA damage, Liver Cancer: Prevention
Pharmacological Actions : Antimutagenic Agents, Antiproliferative , Apoptotic, Chemopreventive
[+]

Sesamin may be a potential chemotherapy drug for liver cancer treatment. Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2013 ;36(10):1540-8. PMID: 24088253
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Lignans, Sesame Seeds, Sesamin
Diseases : Liver Cancer, Liver Cancer: Prevention
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemopreventive, Interleukin-6 Downregulation, STAT3 Inhibitor, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Phytotherapy, Plant Extracts

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