Liver Disease

Name	AC	CK
Vitamin D	2	22
L-Carnitine	1	20
Silymarin	4	15
Curcumin	7	12
Fermented Foods and Beverages	2	12
Garlic	2	12
Coffee	1	10
Magnesium	1	10
Flavonoids	2	3
Ginseng (Korean)	2	3
Licorice	2	3
Melatonin	2	3
Paeoniflorin	2	3
Resveratrol	2	3
Banaba	1	2
Barley	1	2
Blue Honeysuckle	1	2
Blueberry	1	2
Capsaicin	1	2
Carvacrol	1	2
Celery	1	2
Chicory	1	2
Chlorella (Algae)	1	2
Codonopsis lanceolata	1	2
Cysteine (see N-Acetylcysteine)	1	2
Dibenzoylmethane (DBM)	1	2
Eucalyptus	1	2
Fish Oil	1	2
Fucoidan	2	2
Genistein	1	2
Grape	1	2
Kombucha Tea	1	2
Lactobacillus rhamnosus GG	1	2
Maitake Mushroom	1	2
Marijuana	1	2
Milk Thistle	2	2
NAC (N-acetyl-L-cysteine)	1	2
Oregano	1	2
Rosmarinic acid	1	2
Shiitake Mushroom	1	2
Silibinin	1	2
Soursop	1	2
Soy Protein	1	2
Stevia	1	2
Sulforaphane	1	2
Taurine	1	2
Thymoquinone	1	2
Astaxanthin	1	1
Coenzyme Q10	1	1
Cyanidin 3-glucoside	1	1
Emodin	1	1
Ginsenosides	1	1
Indole-3-Carbinol	1	1
Mugwort	1	1
Nigella sativa (aka Black Seed)	1	1
Probiotics	1	1
Purslane	1	1
Quercetin	1	1
Rosemaric Acid	1	1
Royal Jelly	1	1
Tanshinone IIA	1	1
Thistle	1	1

Name	AC	CK
Gluten	2	20
Levothyroxine	2	20
Wheat	2	20
Atorvastatin	2	11
Statin Drugs	2	11
Fluvastatin	1	10
Gliadin	1	10
Proton-Pump Inhibitors	1	10
Simvastatin	1	10
High Fructose Corn Syrup	2	4
Acetaminophen	1	2
Concanavalin A	1	2
Paracetamol	1	2
Triclosan	1	2

Name	AC	CK
Hepatoprotective	1	2
antioxidant	1	2
Stem Cell Related Therapy	1	1

Name	AC	CK
Vaccination: All	1	10
Vaccination: Hepatitis B	1	10
Western Diet	1	2

[+]

Effect of L-carnitine supplementation on lipid profiles of patients with liver disease.Jun 29, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Prev Nutr Food Sci. 2020 Jun 30 ;25(2):124-132. PMID: 32676462

Article Published Date : Jun 29, 2020

Study Type : Meta Analysis, Review

Additional Links

Substances : L-Carnitine

Diseases : Hepatitis C, Liver Disease

Pharmacological Actions : Hypolipidemic

[+]

This study determines the positive efficacy of vitamin D supplementation for chronic liver disease.Apr 30, 2020

Click here to read the entire abstract

Pubmed Data : Medicine (Baltimore). 2020 May ;99(19):e20296. PMID: 32384521

Article Published Date : Apr 30, 2020

Study Type : Meta Analysis, Review

Additional Links

Substances : Vitamin D

Diseases : Liver Disease, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

Celiac disease is found in a far higher percentage of patients with end-stage autoimmune liver disease.Apr 01, 2008

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Liver Int. 2008 Apr;28(4):467-76. PMID: 18339073

Article Published Date : Apr 01, 2008

Study Type : Human Study

Additional Links

Diseases : Autoimmune Diseases, Celiac Disease, End-Stage Autoimmune Liver Disease (ESALD), Liver Disease, Organ Transplantation: Liver

Additional Keywords : Diseases that are Linked

Problem Substances : Gluten, Wheat

[+]

Fermented garlic extracts might be effective and safe management options for mild hepatic dysfunction.Jul 31, 2017

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2017 Aug ;56(5):1993-2002. Epub 2016 Oct 14. PMID: 27743130

Article Published Date : Jul 31, 2017

Study Type : Human Study

Additional Links

Substances : Fermented Foods and Beverages, Garlic

Diseases : Liver Disease

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

For every 100 mg increase in intake of magnesium a 49% reduction in the risk for mortality due to liver diseases was found. Dec 19, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2017 Dec 20 ;7(1):17913. Epub 2017 Dec 20. PMID: 29263344

Article Published Date : Dec 19, 2017

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Alcoholic Liver Disease, Liver Disease

Additional Keywords : Risk Reduction

[+]

Hepatitis B vaccine is associated with an increased risk of liver problems in U.S. children less than 6 years old, 1993 and 1994.May 01, 1999

Click here to read the entire abstract

Pubmed Data : Epidemiology. 1999 May;10(3):337-9. PMID: 10230847

Article Published Date : May 01, 1999

Study Type : Human Study

Additional Links

Diseases : Liver Disease, Vaccine-induced Toxicity

Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B

[+]

Higher coffee consumption was associated with lower risk of elevated aminotransferase concentration in Korean adults.Nov 30, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asia Pac J Clin Nutr. 2016 Dec ;25(4):767-775. PMID: 27702720

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Liver Disease

Pharmacological Actions : Enzyme Inhibitors, Hepatoprotective

[+]

Levothyroxine may be a risk factor for hypoglycaemia in patients with liver disease.Oct 01, 2003

Click here to read the entire abstract

Pubmed Data : J Clin Pharm Ther. 2003 Oct;28(5):355-61. PMID: 14632959

Article Published Date : Oct 01, 2003

Study Type : Human Study

Additional Links

Diseases : Hypoglycemia, Hypothyroidism, Liver Disease

Additional Keywords : Diseases that are Linked

Problem Substances : Levothyroxine

[+]

Levothyroxine use is associated with increased risk of hypoglycemia in patients with liver impairment.Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : Int J Clin Pharmacol Ther. 2008 Jan;46(1):1-13. PMID: 18218292

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Diseases : Hypoglycemia, Hypothyroidism, Liver Disease

Problem Substances : Levothyroxine

[+]

Liver failure and damage are rare but severe unintended consequences of statin drug use.Aug 31, 2011

Click here to read the entire abstract

Pubmed Data : J Hepatol. 2011 Aug 31. Epub 2011 Aug 31. PMID: 21889469

Article Published Date : Aug 31, 2011

Study Type : Human Study

Additional Links

Diseases : Chemically-Induced Liver Damage, Liver Damage, Liver Disease, Liver Failure: Drug Induced, Statin-Induced Pathologies

Problem Substances : Atorvastatin, Fluvastatin, Simvastatin, Statin Drugs

Adverse Pharmacological Actions : Hepatotoxic

[+]

National Health and Nutrition Examination Surveys data collected from 1988 to 2008 show that the prevalence of major causes of CLD remained stable, except for NAFLD, which increased steadily, along with the prevalence of metabolic conditions. Jun 01, 2011

Click here to read the entire abstract

Pubmed Data : Clin Gastroenterol Hepatol. 2011 Jun;9(6):524-530.e1. Epub 2011 Mar 25. PMID: 21440669

Article Published Date : Jun 01, 2011

Study Type : Human Study

Additional Links

Diseases : Liver Disease, Nonalcoholic fatty liver disease (NAFLD)

[+]

Patients with chronic liver disease have a high prevalence of anti-tTg antibodies, similar to patients with celiac disease.Jan 01, 2003

Click here to read the entire abstract

Pubmed Data : Scand J Gastroenterol. 2003 Jan;38(1):50-4. PMID: 12608464

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Diseases : Cirrhosis: Liver, Liver Disease

Additional Keywords : Anti-Endomysium Antibodies, Anti-tTG

Problem Substances : Gliadin, Gluten, Wheat

[+]

Proton pump inhibitor treatment is associated with the severity of liver disease and increased mortality in patients with cirrhosis.Dec 18, 2014

Click here to read the entire abstract

Pubmed Data : Aliment Pharmacol Ther. 2014 Dec 19. Epub 2014 Dec 19. PMID: 25523381

Article Published Date : Dec 18, 2014

Study Type : Human Study

Additional Links

Diseases : Liver Cirrhosis, Liver Disease

Problem Substances : Proton-Pump Inhibitors

[+]

Silymarin in high dose is a good choice for improvement of liver biochemical profile and QoL in chronic hepatitis C virus cirrhotic patients.Oct 31, 2017

Click here to read the entire abstract

Pubmed Data : J Interferon Cytokine Res. 2017 Nov ;37(11):480-487. PMID: 29135373

Article Published Date : Oct 31, 2017

Study Type : Human Study

Additional Links

Substances : Silymarin

Diseases : Hepatitis C, Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

A western-style diet increases liver inflammation in mice with experimentally-induced sepsis.Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : BMC Physiol. 2010;10:20. Epub 2010 Oct 19. PMID: 20958969

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Liver Disease, Sepsis

Anti Therapeutic Actions : Western Diet

[+]

Betulinic acid can be used as an effective agent in the prevention and treatment of acute liver diseases.Mar 27, 2021

Click here to read the entire abstract

Pubmed Data : Turk J Med Sci. 2021 Mar 28. Epub 2021 Mar 28. PMID: 33773522

Article Published Date : Mar 27, 2021

Study Type : Animal Study

Additional Links

Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced, Liver Disease

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

Problem Substances : Acetaminophen, Paracetamol

[+]

Blockage of CCL5 may promote liver regeneration.Sep 03, 2019

Click here to read the entire abstract

Pubmed Data : Cell Mol Immunol. 2019 Sep 3. Epub 2019 Sep 3. PMID: 31481754

Article Published Date : Sep 03, 2019

Study Type : Animal Study

Additional Links

Diseases : Liver Damage, Liver Damage: Drug-Induced, Liver Disease

[+]

Blueberry components could regulate histone acetylation and improve liver pathologic changes in rats with carbon tetrachloride-induced disease.Feb 15, 2017

Click here to read the entire abstract

Pubmed Data : Genet Mol Res. 2017 Feb 16 ;16(1). Epub 2017 Feb 16. PMID: 28218781

Article Published Date : Feb 15, 2017

Study Type : Animal Study

Additional Links

Substances : Blueberry

Diseases : Chemically-Induced Liver Damage, Liver Disease, Liver Fibrosis

Pharmacological Actions : Hepatoprotective

[+]

C. sempervirens and J. phoenicea leaf extracts show a remarkable effect in enhancing liver and kidney functions and may thus be of therapeutic potential in treatment hepatotoxicity and nephrotoxicity.Dec 06, 2010

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : World J Gastrointest Pharmacol Ther. 2010 Dec 6 ;1(6):123-31. PMID: 21577307

Article Published Date : Dec 06, 2010

Study Type : Animal Study

Additional Links

Substances : Flavonoids

Diseases : Liver Disease

Therapeutic Actions : antioxidant, Hepatoprotective

Additional Keywords : C. Sempervirens Extract, J. Phoenicea Extract, Liver Enzymes, Plant Extracts

[+]

Cannabidiol, a non-psychoactive component from Cannabis sativa, may have a therapeutic role in ameloriating cognitive and motor impairments associated with chronic liver disease. Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : J Hepatol. 2009 Sep;51(3):528-34. Epub 2009 May 27. PMID: 19596476

Article Published Date : Sep 01, 2009

Study Type : Animal Study

Additional Links

Substances : Marijuana

Diseases : Liver Disease

[+]

Carvacrol obtained from oregano oil significantly increases the liver regeneration rate in rats undergoing partial hepatectomy. Sep 01, 2007

Click here to read the entire abstract

Pubmed Data : Toxicol Sci. 2007 Sep;99(1):190-202. Epub 2007 Mar 30. PMID: 17689059

Article Published Date : Sep 01, 2007

Study Type : Animal Study

Additional Links

Substances : Carvacrol, Oregano

Diseases : Liver Disease

Additional Keywords : Liver Regeneration, Regenerative Substances

[+]

Celery leaves mixed with chicory leaves and barley grains have a liver protective property in hypercholesterolemic rats.Apr 01, 2011

Click here to read the entire abstract

Pubmed Data : Pharmacogn Mag. 2011 Apr ;7(26):151-6. PMID: 21716923

Article Published Date : Apr 01, 2011

Study Type : Animal Study

Additional Links

Substances : Barley, Celery, Chicory

Diseases : Hypercholesterolemia, Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Chlorella protects the liver from cadmium-induced toxicity in rats.Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : J Med Food. 2008 Sep;11(3):479-85. PMID: 18800895

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Chlorella (Algae)

Diseases : Cadmium Poisoning , Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Codonopsis lanceolata protects against stess-induced liver damage. Oct 01, 2009

Click here to read the entire abstract

Pubmed Data : Arch Pharm Res. 2009 Oct;32(10):1441-6. Epub 2009 Nov 8. PMID: 19898808

Article Published Date : Oct 01, 2009

Study Type : Animal Study

Additional Links

Substances : Codonopsis lanceolata

Diseases : Liver Disease

Pharmacological Actions : Antioxidants, Antiproliferative

[+]

Curcumin attenuates oxidative stress and inflammatory response in the early phase after partial hepatectomy with simultaneous intraabdominal infection in rats.Mar 01, 2010

Click here to read the entire abstract

Pubmed Data : J Surg Res. 2010 Mar;159(1):497-502. Epub 2008 Dec 31. PMID: 19321178

Article Published Date : Mar 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Inflammation, Liver Disease, Liver Surgery, Oxidative Stress

Pharmacological Actions : Hepatoprotective

[+]

Curcumin has protective effects against hepatic ischemia/reperfusion injury. Its mechanism might be related to the overexpression of heat shock protein 70 and antioxidant enzymes.Apr 07, 2007

Click here to read the entire abstract

Pubmed Data : World J Gastroenterol. 2007 Apr 7;13(13):1953-61. PMID: 17461496

Article Published Date : Apr 07, 2007

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Liver Disease

Pharmacological Actions : Antioxidants, Apoptotic, Enzyme Inhibitors, Heat Shock Protein Inducer

Additional Keywords : Heat Shock Protein Inducer

[+]

Curcumin works synergistically with erythropoietin to stimulate liver regeneration.May 01, 2008

Click here to read the entire abstract

Pubmed Data : Langenbecks Arch Surg. 2008 May;393(3):325-32. Epub 2008 Feb 27. PMID: 18301913

Article Published Date : May 01, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Liver Disease

Pharmacological Actions : Antioxidants, Antiproliferative

Additional Keywords : Drug Synergy, Liver Regeneration

[+]

Curcumin, capsaicin and garlic inhibit adverse blood and liver changes associated wtih a high-fat diet in rats.Sep 01, 2004

Click here to read the entire abstract

Pubmed Data : Ann Nutr Metab. 2004 Sep-Oct;48(5):314-20. Epub 2004 Oct 1. PMID: 15467281

Article Published Date : Sep 01, 2004

Study Type : Animal Study

Additional Links

Substances : Capsaicin, Curcumin, Garlic

Diseases : Hyperlipidemia, Liver Disease, Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Dibenzoylmethane protects against carbon tetrachloride induced acute liver injury.Oct 31, 2017

Click here to read the entire abstract

Pubmed Data : AAPS J. 2017 Nov ;19(6):1703-1714. Epub 2017 Aug 21. PMID: 28828752

Article Published Date : Oct 31, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Dibenzoylmethane (DBM)

Diseases : Chemically-Induced Liver Damage, Liver Disease

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Nrf2 activation

[+]

Dietary rosmarinic acid supplementation may be beneficial in terms of improving cholestasis-related liver injury.Aug 04, 2017

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2017 Aug 5 ;108(Pt A):214-223. Epub 2017 Aug 5. PMID: 28789951

Article Published Date : Aug 04, 2017

Study Type : Animal Study

Additional Links

Substances : Rosmarinic acid

Diseases : Cholestasis, Liver Disease

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor

[+]

Efficacy of a Peruvian botanical remedy (Sabell A4+) for treating liver disease and protecting gastric mucosal integrity.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:5486728. Epub 2019 Oct 24. PMID: 31781272

Article Published Date : Dec 31, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin, Soursop

Diseases : Liver Disease

Pharmacological Actions : Gastroprotective, Hepatoprotective

[+]

Eucalyptus and banaba inhibit NASH induced by high-fructose and high-glucose diet in rats.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2015 ;2015:296207. Epub 2015 Apr 27. PMID: 26000287

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Banaba, Eucalyptus

Diseases : High Fructose Diet, Liver Disease, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Fish oil (but not olive oil) improves liver regeneration in rats subjected to partial hepatectomy. Mar 01, 2006

Click here to read the entire abstract

Pubmed Data : Transplant Proc. 2006 Mar;38(2):564-7. PMID: 16549176

Article Published Date : Mar 01, 2006

Study Type : Animal Study

Additional Links

Substances : Fish Oil

Diseases : Liver Disease

[+]

G. frondosa may prevent the further development of NASH by improving the disorder of lipid metabolism in rats.Apr 30, 2015

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2015 May ;40(9):1808-11. PMID: 26323153

Article Published Date : Apr 30, 2015

Study Type : Animal Study

Additional Links

Substances : Maitake Mushroom

Diseases : Hepatic Steatosis, Liver Disease

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypolipidemic, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Grape juice has a liver protecting properties in rats. Mar 01, 2008

Click here to read the entire abstract

Pubmed Data : J Med Food. 2008 Mar;11(1):127-32. PMID: 18361748

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Grape

Diseases : Liver Disease

Pharmacological Actions : Antioxidants

[+]

High fat, high fructose, high cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile ossabaw swine.Sep 11, 2017

Click here to read the entire abstract

Pubmed Data : Am J Physiol Endocrinol Metab. 2017 Sep 12:ajpendo.00015.2017. Epub 2017 Sep 12. PMID: 28899857

Article Published Date : Sep 11, 2017

Study Type : Animal Study

Additional Links

Diseases : Dysbiosis, High Fat Diet, High Fructose Diet, Liver Disease, Obesity

Additional Keywords : Risk Factors

Problem Substances : High Fructose Corn Syrup

[+]

Kombucha tea exhibits anti-stress and liver protecting properties. Sep 01, 2001

Click here to read the entire abstract

Pubmed Data : Biomed Environ Sci. 2001 Sep;14(3):207-13. PMID: 11723720

Article Published Date : Sep 01, 2001

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Kombucha Tea

Diseases : Liver Disease

[+]

Korean ginseng accelerates the rate of liver regeneration and ameliorated the liver injury after partial hepatectomy in rats. Feb 01, 2004

Click here to read the entire abstract

Pubmed Data : J Vet Med Sci. 2004 Feb;66(2):193-5. PMID: 15031549

Article Published Date : Feb 01, 2004

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Liver Disease

Additional Keywords : Liver Regeneration

[+]

Lactobacillus rhamnosus GG reduces hepatic fibrosis in animals.Jan 04, 2017

Click here to read the entire abstract

Pubmed Data : Nutr Hosp. 2017 06 5 ;34(3):702-709. Epub 2017 Jun 5. PMID: 28627210

Article Published Date : Jan 04, 2017

Study Type : Animal Study

Additional Links

Substances : Lactobacillus rhamnosus GG

Diseases : Fibrosis, Liver Disease

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation

[+]

Lipid metabolism disorders contribute to hepatotoxicity of triclosan in mice.Sep 23, 2019

Click here to read the entire abstract

Pubmed Data : J Hazard Mater. 2019 Sep 24 ;384:121310. Epub 2019 Sep 24. PMID: 31586915

Article Published Date : Sep 23, 2019

Study Type : Animal Study

Additional Links

Diseases : Chemically-Induced Liver Damage, Liver Disease

Problem Substances : Triclosan

[+]

Melatonin restores liver mitochondrial physiology in old mice.Mar 01, 2003

Click here to read the entire abstract

Pubmed Data : Int J Biochem Cell Biol. 2003 Mar;35(3):367-75. PMID: 12531250

Article Published Date : Mar 01, 2003

Study Type : Animal Study

Additional Links

Substances : Melatonin

Diseases : Aging, Liver Disease

Pharmacological Actions : Antioxidants, Hepatoprotective, Regenerative

[+]

N-acetyl cysteine attenuates the sarcopenia and muscle apoptosis induced by chronic liver disease.Sep 16, 2019

Click here to read the entire abstract

Pubmed Data : Curr Mol Med. 2019 Sep 17. Epub 2019 Sep 17. PMID: 31530262

Article Published Date : Sep 16, 2019

Study Type : Animal Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Liver Disease, Sarcopenia

Pharmacological Actions : Anti-Apoptotic

[+]

Paeoniflorin is predicted to be a potential therapy for chronic hepatic diseases associated with fibrosis and angiogenesis.Jan 31, 2019

Click here to read the entire abstract

Pubmed Data : Exp Parasitol. 2019 Feb ;197:85-92. Epub 2018 Nov 8. PMID: 30414842

Article Published Date : Jan 31, 2019

Study Type : Animal Study

Additional Links

Substances : Paeoniflorin

Diseases : Liver Disease, Schistosomiasis

Pharmacological Actions : Anti-Angiogenic, Anti-Fibrotic, Vascular Endothelial Growth Factor Inhibitors

[+]

Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis.Mar 31, 2017

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2017 Apr ;61(4). Epub 2017 Feb 15. PMID: 27935258

Article Published Date : Mar 31, 2017

Study Type : Animal Study

Additional Links

Substances : Blue Honeysuckle

Diseases : Liver Disease, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation

[+]

Resveratrol supplementation considerably restored hepatic changes induced by high fructose corn syrup.Sep 10, 2014

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2014 Sep 11. Epub 2014 Sep 11. PMID: 25238689

Article Published Date : Sep 10, 2014

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Liver Disease

Pharmacological Actions : Hepatoprotective, SIRT1 Activator

Additional Keywords : Risk Reduction

Problem Substances : High Fructose Corn Syrup

[+]

Silybin was effective in preventing the methionine-choline deficient-induced increases in hepatic steatosis, fibrosis and inflammation.Sep 05, 2018

Click here to read the entire abstract

Pubmed Data : Dig Dis Sci. 2018 Sep 6. Epub 2018 Sep 6. PMID: 30191499

Article Published Date : Sep 05, 2018

Study Type : Animal Study

Additional Links

Substances : Silibinin

Diseases : Hepatic Steatosis, Liver Disease, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

Soy protein isolate reduces fatty liver in a mouse model of non-alchohlic liver disease. Nov 13, 2010

Click here to read the entire abstract

Pubmed Data : Neurotox Res. 2010 Nov 13. Epub 2010 Nov 13. PMID: 18791133

Article Published Date : Nov 13, 2010

Study Type : Animal Study

Additional Links

Substances : Genistein, Soy Protein

Diseases : Fatty Liver, Liver Disease

[+]

Stevia prevents experimental cirrhosis by reducing hepatic myofibroblasts and modulating molecular profibrotic pathways.Jan 31, 2019

Click here to read the entire abstract

Pubmed Data : Hepatol Res. 2019 Feb ;49(2):212-223. Epub 2018 Nov 19. PMID: 30338893

Article Published Date : Jan 31, 2019

Study Type : Animal Study

Additional Links

Substances : Stevia

Diseases : Liver Cirrhosis, Liver Disease

Pharmacological Actions : Hepatoprotective, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor, Transforming growth factor beta (TGF-β) inhibitor

[+]

Sulforaphane protects liver injury induced by intestinal ischemia in an animal model. Jun 28, 2010

Click here to read the entire abstract

Pubmed Data : World J Gastroenterol. 2010 Jun 28;16(24):3002-10. PMID: 20572303

Article Published Date : Jun 28, 2010

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Intestinal Diseases, Liver Disease

Pharmacological Actions : Anticarcinogenic Agents, Antioxidants

[+]

Taurine may be used in combination with silymarin as an additional adjunct therapy to cure liver diseases such as fibrosis, cirrhosis and viral hepatitis.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(12):e0144509. Epub 2015 Dec 11. PMID: 26659465

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Silymarin, Taurine

Diseases : Chemically-Induced Liver Damage, Liver Cirrhosis, Liver Disease, Liver Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

[+]

The compound found in Licorice known as glycyrrhizin accelerates liver regeneration and recovery from liver damaged in partially hepatectomized rats. Jan 28, 2008

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2008 Jan 28;579(1-3):357-64. Epub 2007 Nov 1. PMID: 18022618

Article Published Date : Jan 28, 2008

Study Type : Animal Study

Additional Links

Substances : Licorice

Diseases : Liver Disease

Additional Keywords : Liver Regeneration, Regenerative Substances

[+]

These findings suggest that thymoquinone, silymarin, and N-acetylcysteine have potential for the treatment of diseases causing liver injury.Jul 29, 2018

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2018 Jul 30 ;106:1705-1712. Epub 2018 Jul 30. PMID: 30119245

Article Published Date : Jul 29, 2018

Study Type : Animal Study

Additional Links

Substances : Cysteine (see N-Acetylcysteine), Silymarin, Thymoquinone

Diseases : Liver Damage, Liver Disease

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

[+]

Vitamin D-enriched Shiitake mushroom exerts a synergistic anti-inflammatory effect in an immune-mediated hepatitis model.Mar 29, 2016

Click here to read the entire abstract

Pubmed Data : J Med Food. 2016 Mar 30. Epub 2016 Mar 30. PMID: 27027234

Article Published Date : Mar 29, 2016

Study Type : Animal Study

Additional Links

Substances : Shiitake Mushroom , Vitamin D

Diseases : Chemically-Induced Liver Damage, Hepatitis C, Liver Disease

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

Additional Keywords : Natural Substance Synergy, Plant Extracts

Problem Substances : Concanavalin A

[+]

The effect of emodin on liver disease - comprehensive advances in molecular mechanisms.Sep 04, 2020

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2020 Sep 5 ;882:173269. Epub 2020 Jun 14. PMID: 32553811

Article Published Date : Sep 04, 2020

Study Type : Review

Additional Links

Substances : Emodin

Diseases : Liver Cancer, Liver Damage, Liver Disease, Liver Fibrosis, Organ Transplantation: Liver

Pharmacological Actions : Anti-Fibrotic, Antioxidants, Apoptotic, Hepatoprotective, Hypolipidemic, Immunomodulatory, Transforming growth factor beta (TGF-β) inhibitor

[+]

A review of the hepataprotective effects of ginsenoside Rg1.Apr 16, 2017

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2017 Apr 17. Epub 2017 Apr 17. PMID: 28427912

Article Published Date : Apr 16, 2017

Study Type : Review

Additional Links

Substances : Ginsenosides

Diseases : Liver Damage, Liver Disease

Pharmacological Actions : Hepatoprotective

Additional Keywords : Ginsenosides, Hepatoprotective, liver damage, Liver Disease

[+]

An overview of coenzyme Q10 and degenerative disorders affecting longevity.Feb 15, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2019 Feb 16 ;8(2). Epub 2019 Feb 16. PMID: 30781472

Article Published Date : Feb 15, 2019

Study Type : Review

Additional Links

Substances : Coenzyme Q10

Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2, Kidney Diseases, Liver Disease

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypoglycemic Agents, Renoprotective

[+]

Astaxanthin in liver health and disease: a potential therapeutic agent.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Drug Des Devel Ther. 2020 ;14:2275-2285. Epub 2020 Jun 9. PMID: 32606597

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Substances : Astaxanthin

Diseases : Liver Cancer, Liver Disease, Liver Fibrosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

[+]

Cirsium japonicum might be a preventative treatment of NAFLD.Jun 30, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2014 Jul ;8(1):79-84. Epub 2014 Apr 25. PMID: 24944601

Article Published Date : Jun 30, 2014

Study Type : In Vitro Study

Additional Links

Substances : Thistle

Diseases : Liver Disease, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Plant Extracts

[+]

Cocoa flavonoids may prevent oxidative-stress-induced damage to the liver.Mar 01, 2010

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2010 Mar;21(3):196-205. Epub 2009 Feb 5. PMID: 19195869

Article Published Date : Mar 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Liver Disease, Oxidative Stress

Pharmacological Actions : Antioxidants, Apoptotic, Hepatoprotective

Additional Keywords : Plant Extracts

[+]

Curcumin as a therapeutic strategy in liver diseases.Oct 16, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 Oct 17 ;11(10). Epub 2019 Oct 17. PMID: 31627369

Article Published Date : Oct 16, 2019

Study Type : Review

Additional Links

Substances : Curcumin

Diseases : Liver Disease, Liver Failure: Acute, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Cyanidin-3-glucoside enhances mitochondrial function and biogenesis in a human hepatocyte cell line.Nov 30, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cytotechnology. 2018 Dec ;70(6):1519-1528. Epub 2018 Aug 28. PMID: 30155610

Article Published Date : Nov 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Cyanidin 3-glucoside

Diseases : Liver Damage, Liver Disease, Mitochondrial Dysfunction

Pharmacological Actions : Hepatoprotective

[+]

Fucoidan: Biological Activity in Liver Diseases Nov 04, 2020

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2020 Nov 5:1-16. Epub 2020 Nov 5. PMID: 33148007

Article Published Date : Nov 04, 2020

Study Type : Review

Additional Links

Substances : Fucoidan

Diseases : Ischemia, Liver Cancer, Liver Damage: Drug-Induced, Liver Disease, Liver Fibrosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Polysaccharides

[+]

Hepatoprotective activity of aqueous-methanol extract of Artemisia vulgaris.Jan 31, 2005

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2005 Feb ;19(2):170-2. PMID: 15852491

Article Published Date : Jan 31, 2005

Study Type : In Vitro Study

Additional Links

Substances : Mugwort

Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage, Liver Disease

Pharmacological Actions : Hepatoprotective

Additional Keywords : Phytotherapy, Plant Extracts

[+]

In a pooled analysis of trials in patients with cirrhosis, silymarin treatment was associated with a significant reduction in liver-related deaths.Feb 17, 2020

Click here to read the entire abstract

Pubmed Data : Adv Ther. 2020 Feb 17. Epub 2020 Feb 17. PMID: 32065376

Article Published Date : Feb 17, 2020

Study Type : Review

Additional Links

Substances : Milk Thistle, Silymarin

Diseases : Liver Disease

Pharmacological Actions : Hepatoprotective, Regenerative

Additional Keywords : Liver Regeneration

[+]

Indole-3-carbinol and its major derivatives: Their pharmacokinetics and important roles in hepatic protection.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Curr Drug Metab. 2016 ;17(4):401-9. PMID: 26651978

Article Published Date : Dec 31, 2015

Study Type : Review

Additional Links

Substances : Indole-3-Carbinol

Diseases : Liver Damage, Liver Disease, Liver Fibrosis, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic, Hepatoprotective

[+]

Mesenchymal stem cell therapies for liver cirrhosis: MSCs as "conducting cells" for improvement of liver fibrosis and regeneration.Jan 01, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Inflamm Regen. 2019 ;39:18. Epub 2019 Sep 9. PMID: 31516638

Article Published Date : Jan 01, 2019

Study Type : Review

Additional Links

Diseases : Liver Cirrhosis, Liver Cirrhosis: Alcoholic , Liver Damage, Liver Disease

Therapeutic Actions : Stem Cell Related Therapy

Additional Keywords : Liver Regeneration

[+]

Molecular updates on berberine in liver diseases: Bench to bedside.May 30, 2021

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2021 May 31. Epub 2021 May 31. PMID: 34056769

Article Published Date : May 30, 2021

Study Type : Review

Additional Links

Substances : Berberine

Diseases : Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Natural products in licorice for the therapy of liver diseases.Dec 31, 2018

Click here to read the entire abstract

Pubmed Data : Pharmacol Res. 2019 06 ;144:210-226. Epub 2019 Apr 22. PMID: 31022523

Article Published Date : Dec 31, 2018

Study Type : Review

Additional Links

Substances : Licorice

Diseases : Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Need for serological tests to exclude celiac disease when TSH and CK values non-indicative.Jul 18, 2007

Click here to read the entire abstract

Pubmed Data : MMW Fortschr Med. 2007 Jul 19 ;149(29-30):44-8; quiz 49. PMID: 17703692

Article Published Date : Jul 18, 2007

Study Type : Review

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations, Hepatitis, Liver Disease

[+]

Oligo-fucoidan enhances the immune system and protects hepatocytes.Jun 11, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomolecules. 2020 Jun 12 ;10(6). Epub 2020 Jun 12. PMID: 32545625

Article Published Date : Jun 11, 2020

Study Type : In Vitro Study

Additional Links

Substances : Fucoidan

Diseases : Liver Disease

Pharmacological Actions : Antiviral Agents, Immunomodulatory

[+]

Paeoniflorin is a natural product with multiple targets in liver diseases.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:531. Epub 2020 Apr 28. PMID: 32410996

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Substances : Paeoniflorin

Diseases : Liver Cancer, Liver Disease, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Anti-metastatic, Antioxidants, Apoptotic, Hepatoprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Immunomodulatory, NF-kappaB Inhibitor, Nrf2 activation, Transforming growth factor beta (TGF-β) inhibitor

[+]

Patients with NASH was observed have a distinct gut microbiota when compared to control groups.Sep 04, 2017

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2017 Sep 5. Epub 2017 Sep 5. PMID: 28875318

Article Published Date : Sep 04, 2017

Study Type : Review

Additional Links

Diseases : Liver Disease, Nonalcoholic fatty liver disease (NAFLD)

Additional Keywords : Microbiota

[+]

Preventive and therapeutic role of Tanshinone ⅡA in hepatology.Mar 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2019 Apr ;112:108676. Epub 2019 Feb 21. PMID: 30797157

Article Published Date : Mar 31, 2019

Study Type : Review

Additional Links

Substances : Tanshinone IIA

Diseases : Fatty Liver, Liver Cancer, Liver Damage, Liver Disease, Liver Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemotherapeutic, Hepatoprotective

[+]

Probiotics have demonstrated some benefit in several specific gastrointestinal and liver diseases.Dec 31, 2018

Click here to read the entire abstract

Pubmed Data : Endocr Metab Immune Disord Drug Targets. 2019 ;19(5):549-570. PMID: 30360751

Article Published Date : Dec 31, 2018

Study Type : Review

Additional Links

Substances : Probiotics

Diseases : Gastrointestinal Diseases, Liver Disease

Pharmacological Actions : Gastrointestinal Agents

[+]

Quercetin protects human liver cells from ethanol-induced oxidative stress. Aug 01, 2007

Click here to read the entire abstract

Pubmed Data : J Hepatol. 2007 Aug;47(2):253-61. Epub 2007 Mar 7. PMID: 17433488

Article Published Date : Aug 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Quercetin

Diseases : Liver Disease, Oxidative Stress

Pharmacological Actions : Hepatoprotective

[+]

Resveratrol may have therapeutic value in liver disease. Sep 01, 2010

Click here to read the entire abstract

Pubmed Data : Liver Int. 2010 Sep;30(8):1103-14. Epub 2010 Jun 14. PMID: 20557453

Article Published Date : Sep 01, 2010

Study Type : Review

Additional Links

Substances : Resveratrol

Diseases : Acetaminophen (Tylenol) Toxicity , Alcohol Toxicity , Liver Disease

Pharmacological Actions : Antioxidants, Hepatoprotective, NF-kappaB Inhibitor

Additional Keywords : Stilbenes

[+]

Review: Drug-induced liver injury associated with statins.Nov 01, 2009

Click here to read the entire abstract

Pubmed Data : Semin Liver Dis. 2009 Nov ;29(4):412-22. Epub 2009 Oct 13. PMID: 19826975

Article Published Date : Nov 01, 2009

Study Type : Review

Additional Links

Diseases : Chemically-Induced Liver Damage, Hepatitis: Autoimmune , Hepatitis: Cholestatic, Liver Damage, Liver Disease, Statin-Induced Pathologies

Problem Substances : Atorvastatin, Statin Drugs

Adverse Pharmacological Actions : Hepatotoxic

[+]

Rosmarinic acid stimulates liver regeneration through the mTOR pathway.Nov 30, 2016

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2016 Dec 1 ;23(13):1574-1582. Epub 2016 Sep 30. PMID: 27823621

Article Published Date : Nov 30, 2016

Study Type : In Vitro Study

Additional Links

Substances : Rosemaric Acid

Diseases : Liver Disease

Pharmacological Actions : mTOR/S6K pathway Activator

Additional Keywords : Regenerative Substances

[+]

The endocannabinoid system may play an important role in liver diseases.Oct 07, 2010

Click here to read the entire abstract

Pubmed Data : Dig Liver Dis. 2010 Oct 7. Epub 2010 Oct 7. PMID: 20934397

Article Published Date : Oct 07, 2010

Study Type : Commentary

Additional Links

Diseases : Endocannabinoid System, Liver Disease

[+]

The information presented in this paper identifies curcumin as a promising renoprotective molecule against renal injury. Dec 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Redox Biol. 2013 ;1:448-56. Epub 2013 Sep 17. PMID: 24191240

Article Published Date : Dec 31, 2012

Study Type : Review

Additional Links

Substances : Curcumin

Diseases : Liver Damage, Liver Damage: Drug-Induced, Liver Disease, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Renoprotective

[+]

The mechanisms by which N. sativa impede progression in chronic liver diseases should be used as a preventive medicine in patients with hepatic disorders.Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Curr Pharm Biotechnol. 2018 ;19(1):43-67. PMID: 29701149

Article Published Date : Dec 31, 2017

Study Type : Review

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : Lipid Peroxidation, Liver Damage, Liver Disease

Pharmacological Actions : Antioxidants, Hepatoprotective, Superoxide Dismutase Up-regulation

Additional Keywords : Plant Extracts

[+]

The therapeutic effects of Portulaca oleracea L. in hepatogastric disorders.Jan 31, 2019

Click here to read the entire abstract

Pubmed Data : Gastroenterol Hepatol. 2019 Feb ;42(2):127-132. Epub 2018 Oct 13. PMID: 30327154

Article Published Date : Jan 31, 2019

Study Type : Review

Additional Links

Substances : Purslane

Diseases : Gastrointestinal Complaints, Liver Disease

Pharmacological Actions : Gastroprotective, Hepatoprotective

[+]

This paper summarizes the current knowledge on the beneficial effects of Korean red ginseng on chronic liver disease.Sep 30, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Ginseng Res. 2017 Oct ;41(4):450-455. Epub 2017 Jan 5. PMID: 29021690

Article Published Date : Sep 30, 2017

Study Type : Review

Additional Links

Substances : Ginseng (Korean)

Diseases : Hepatitis C, Liver Cancer, Liver Disease, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

This review article aims to present different aspects of Silybum marianum, especially the data in recently published articles about its effects on different diseases.Sep 30, 2015

Click here to read the entire abstract

Pubmed Data : J Evid Based Complementary Altern Med. 2015 Oct ;20(4):292-301. Epub 2015 Feb 16. PMID: 25686616

Article Published Date : Sep 30, 2015

Study Type : Review

Additional Links

Substances : Milk Thistle

Diseases : Alzheimer's Disease, Cancers: All, Insulin Resistance, Liver Cirrhosis, Liver Disease

Pharmacological Actions : Anti-atherogenic, Antioxidants, Cardiovascular Agents, Hepatoprotective, Hypolipidemic, Regenerative

[+]

This reviews the potential roles of melatonin in liver injuries and diseases, paying special attention to the mechanisms of action.Mar 22, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2017 Mar 23 ;18(4). Epub 2017 Mar 23. PMID: 28333073

Article Published Date : Mar 22, 2017

Study Type : Review

Additional Links

Substances : Melatonin

Diseases : Liver Damage, Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Two purified proteins from royal jelly with in vitro dual anti-hepatic damage potency.Jan 31, 2019

Click here to read the entire abstract

Pubmed Data : Int J Biol Macromol. 2019 Feb 1 ;128:782-795. Epub 2019 Feb 1. PMID: 30711561

Article Published Date : Jan 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Royal Jelly

Diseases : Liver Disease

Pharmacological Actions : Hepatoprotective

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View the Evidence: 86 Abstracts with Liver Disease Research

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Effect of L-carnitine supplementation on lipid profiles of patients with liver disease.Jun 29, 2020

This study determines the positive efficacy of vitamin D supplementation for chronic liver disease.Apr 30, 2020

Celiac disease is found in a far higher percentage of patients with end-stage autoimmune liver disease.Apr 01, 2008

Fermented garlic extracts might be effective and safe management options for mild hepatic dysfunction.Jul 31, 2017

For every 100 mg increase in intake of magnesium a 49% reduction in the risk for mortality due to liver diseases was found. Dec 19, 2017

Hepatitis B vaccine is associated with an increased risk of liver problems in U.S. children less than 6 years old, 1993 and 1994.May 01, 1999

Higher coffee consumption was associated with lower risk of elevated aminotransferase concentration in Korean adults.Nov 30, 2016

Levothyroxine may be a risk factor for hypoglycaemia in patients with liver disease.Oct 01, 2003

Levothyroxine use is associated with increased risk of hypoglycemia in patients with liver impairment.Jan 01, 2008

Liver failure and damage are rare but severe unintended consequences of statin drug use.Aug 31, 2011

National Health and Nutrition Examination Surveys data collected from 1988 to 2008 show that the prevalence of major causes of CLD remained stable, except for NAFLD, which increased steadily, along with the prevalence of metabolic conditions. Jun 01, 2011

Patients with chronic liver disease have a high prevalence of anti-tTg antibodies, similar to patients with celiac disease.Jan 01, 2003

Proton pump inhibitor treatment is associated with the severity of liver disease and increased mortality in patients with cirrhosis.Dec 18, 2014

Silymarin in high dose is a good choice for improvement of liver biochemical profile and QoL in chronic hepatitis C virus cirrhotic patients.Oct 31, 2017

A western-style diet increases liver inflammation in mice with experimentally-induced sepsis.Jan 01, 2010

Betulinic acid can be used as an effective agent in the prevention and treatment of acute liver diseases.Mar 27, 2021

Blockage of CCL5 may promote liver regeneration.Sep 03, 2019

Blueberry components could regulate histone acetylation and improve liver pathologic changes in rats with carbon tetrachloride-induced disease.Feb 15, 2017

C. sempervirens and J. phoenicea leaf extracts show a remarkable effect in enhancing liver and kidney functions and may thus be of therapeutic potential in treatment hepatotoxicity and nephrotoxicity.Dec 06, 2010

Cannabidiol, a non-psychoactive component from Cannabis sativa, may have a therapeutic role in ameloriating cognitive and motor impairments associated with chronic liver disease. Sep 01, 2009

Carvacrol obtained from oregano oil significantly increases the liver regeneration rate in rats undergoing partial hepatectomy. Sep 01, 2007

Celery leaves mixed with chicory leaves and barley grains have a liver protective property in hypercholesterolemic rats.Apr 01, 2011

Chlorella protects the liver from cadmium-induced toxicity in rats.Sep 01, 2008

Codonopsis lanceolata protects against stess-induced liver damage. Oct 01, 2009

Curcumin attenuates oxidative stress and inflammatory response in the early phase after partial hepatectomy with simultaneous intraabdominal infection in rats.Mar 01, 2010

Curcumin has protective effects against hepatic ischemia/reperfusion injury. Its mechanism might be related to the overexpression of heat shock protein 70 and antioxidant enzymes.Apr 07, 2007

Curcumin works synergistically with erythropoietin to stimulate liver regeneration.May 01, 2008

Curcumin, capsaicin and garlic inhibit adverse blood and liver changes associated wtih a high-fat diet in rats.Sep 01, 2004

Dibenzoylmethane protects against carbon tetrachloride induced acute liver injury.Oct 31, 2017

Dietary rosmarinic acid supplementation may be beneficial in terms of improving cholestasis-related liver injury.Aug 04, 2017

Efficacy of a Peruvian botanical remedy (Sabell A4+) for treating liver disease and protecting gastric mucosal integrity.Dec 31, 2018

Eucalyptus and banaba inhibit NASH induced by high-fructose and high-glucose diet in rats.Dec 31, 2014

Fish oil (but not olive oil) improves liver regeneration in rats subjected to partial hepatectomy. Mar 01, 2006

G. frondosa may prevent the further development of NASH by improving the disorder of lipid metabolism in rats.Apr 30, 2015

Grape juice has a liver protecting properties in rats. Mar 01, 2008

High fat, high fructose, high cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile ossabaw swine.Sep 11, 2017

Kombucha tea exhibits anti-stress and liver protecting properties. Sep 01, 2001

Korean ginseng accelerates the rate of liver regeneration and ameliorated the liver injury after partial hepatectomy in rats. Feb 01, 2004

Lactobacillus rhamnosus GG reduces hepatic fibrosis in animals.Jan 04, 2017

Lipid metabolism disorders contribute to hepatotoxicity of triclosan in mice.Sep 23, 2019

Melatonin restores liver mitochondrial physiology in old mice.Mar 01, 2003

N-acetyl cysteine attenuates the sarcopenia and muscle apoptosis induced by chronic liver disease.Sep 16, 2019

Paeoniflorin is predicted to be a potential therapy for chronic hepatic diseases associated with fibrosis and angiogenesis.Jan 31, 2019

Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis.Mar 31, 2017

Resveratrol supplementation considerably restored hepatic changes induced by high fructose corn syrup.Sep 10, 2014

Silybin was effective in preventing the methionine-choline deficient-induced increases in hepatic steatosis, fibrosis and inflammation.Sep 05, 2018

Soy protein isolate reduces fatty liver in a mouse model of non-alchohlic liver disease. Nov 13, 2010

Stevia prevents experimental cirrhosis by reducing hepatic myofibroblasts and modulating molecular profibrotic pathways.Jan 31, 2019

Sulforaphane protects liver injury induced by intestinal ischemia in an animal model. Jun 28, 2010

Taurine may be used in combination with silymarin as an additional adjunct therapy to cure liver diseases such as fibrosis, cirrhosis and viral hepatitis.Dec 31, 2014

The compound found in Licorice known as glycyrrhizin accelerates liver regeneration and recovery from liver damaged in partially hepatectomized rats. Jan 28, 2008

These findings suggest that thymoquinone, silymarin, and N-acetylcysteine have potential for the treatment of diseases causing liver injury.Jul 29, 2018

Vitamin D-enriched Shiitake mushroom exerts a synergistic anti-inflammatory effect in an immune-mediated hepatitis model.Mar 29, 2016

The effect of emodin on liver disease - comprehensive advances in molecular mechanisms.Sep 04, 2020

A review of the hepataprotective effects of ginsenoside Rg1.Apr 16, 2017

An overview of coenzyme Q10 and degenerative disorders affecting longevity.Feb 15, 2019

Astaxanthin in liver health and disease: a potential therapeutic agent.Dec 31, 2019

Cirsium japonicum might be a preventative treatment of NAFLD.Jun 30, 2014

Cocoa flavonoids may prevent oxidative-stress-induced damage to the liver.Mar 01, 2010

Curcumin as a therapeutic strategy in liver diseases.Oct 16, 2019

Cyanidin-3-glucoside enhances mitochondrial function and biogenesis in a human hepatocyte cell line.Nov 30, 2018

Fucoidan: Biological Activity in Liver Diseases Nov 04, 2020

Hepatoprotective activity of aqueous-methanol extract of Artemisia vulgaris.Jan 31, 2005

In a pooled analysis of trials in patients with cirrhosis, silymarin treatment was associated with a significant reduction in liver-related deaths.Feb 17, 2020

Indole-3-carbinol and its major derivatives: Their pharmacokinetics and important roles in hepatic protection.Dec 31, 2015

Mesenchymal stem cell therapies for liver cirrhosis: MSCs as "conducting cells" for improvement of liver fibrosis and regeneration.Jan 01, 2019

Molecular updates on berberine in liver diseases: Bench to bedside.May 30, 2021

Natural products in licorice for the therapy of liver diseases.Dec 31, 2018

Need for serological tests to exclude celiac disease when TSH and CK values non-indicative.Jul 18, 2007

Oligo-fucoidan enhances the immune system and protects hepatocytes.Jun 11, 2020

Paeoniflorin is a natural product with multiple targets in liver diseases.Dec 31, 2019

Patients with NASH was observed have a distinct gut microbiota when compared to control groups.Sep 04, 2017

Liver Disease

View the Evidence:
86 Abstracts with Liver Disease Research