Liver Failure: Acute

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18 Substances Researched for Liver Failure: Acute
NameACCKFocus
Ginsenosides24Locked
NAC (N-acetyl-L-cysteine)13Locked
Acai12Locked
Apigenin12Locked
Bacopa12Locked
Bee Venom12Locked
Cannabidiol12Locked
Cannabis12Locked
Chrysin12Locked
Dandelion 12Locked
Diosmetin12Locked
Ginseng12Locked
Luteolin12Locked
Paeonol12Locked
Schisandra12Locked
Asiatic Acid11Locked
Curcumin11Locked
Sulforaphane11Locked

View the Evidence:
20 Abstracts with Liver Failure: Acute Research

[+]

NAC therapy should be considered early in the course of heat injury-mediated ischemic hepatitis.Feb 26, 2019

Pubmed Data : Mil Med. 2019 Feb 27. Epub 2019 Feb 27. PMID: 30811527
Article Published Date : Feb 26, 2019
Study Type : Human: Case Report
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Hepatitis, Liver Failure: Acute
Pharmacological Actions : Cytoprotective
[+]

Pinocembrin ameliorates acute liver failure via activating the Sirt1/PPARα pathway in vitro and in vivo.Jan 14, 2022

Pubmed Data : Eur J Pharmacol. 2022 Jan 15 ;915:174610. Epub 2021 Dec 21. PMID: 34951978
Article Published Date : Jan 14, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

Melittin ameliorates inflammation in mouse acute liver failure via inhibition of PKM2-mediated Warburg effect.Sep 15, 2020

Pubmed Data : Acta Pharmacol Sin. 2020 Sep 16. Epub 2020 Sep 16. PMID: 32939034
Article Published Date : Sep 15, 2020
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Liver Damage, Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
[+]

Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.Apr 30, 2017

Pubmed Data : Int Immunopharmacol. 2017 May ;46:124-132. Epub 2017 Mar 7. PMID: 28282576
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Failure: Acute
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor
[+]

Apigenin has good hepatoprotective effects and potential as a promising therapeutic agent for acute liver failure in clinical application.Jan 10, 2019

Pubmed Data : Int Immunopharmacol. 2019 Jan 11 ;68:171-178. Epub 2019 Jan 11. PMID: 30641432
Article Published Date : Jan 10, 2019
Study Type : Animal Study
Additional Links
Substances : Apigenin, Chrysin, Luteolin
Diseases : Liver Failure: Acute
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Malondialdehyde Down-regulation, Nrf2 activation, Superoxide Dismutase Up-regulation
[+]

Bacopa monnieri extract prevents the neurochemical alterations associated with hepatic encephalopathy.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:535013. Epub 2015 Aug 27. PMID: 26413124
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Hepatic Encephalopathy, Liver Failure: Acute
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice.Dec 23, 2010

Pubmed Data : Br J Pharmacol. 2010 Dec 23. Epub 2010 Dec 23. PMID: 21182490
Article Published Date : Dec 23, 2010
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Cannabis
Diseases : Fulminant Hepatic Failure, Hepatic Encephalopathy, Liver Failure: Acute
Pharmacological Actions : Hepatoprotective, Neuroprotective Agents
[+]

Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure.May 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 May 9 ;8(19):30723-30733. PMID: 28430612
Article Published Date : May 08, 2017
Study Type : Animal Study
Additional Links
Substances : Diosmetin
Diseases : Endotoxemia, Liver Damage, Liver Failure: Acute, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor
[+]

Ginsenoside Rg1 significantly reduces liver damage in an acute liver failure model.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2014 ;2014:538059. Epub 2014 Oct 28. PMID: 25431611
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gomisin A, a compound found within Schisandra, has a protective effect in fulminant liver failure. Jan 01, 2004

Pubmed Data : Asia Pac J Clin Nutr. 2004;13(2):210-6. PMID: 18270473
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Schisandra
Diseases : Fulminant Hepatic Failure, Liver Failure: Acute
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Hepatoprotective effect of diallyl trisulfide against lipopolysaccharide and D-galactosamine induced acute liver failure.Mar 31, 2022

Pubmed Data : Toxicol Res (Camb). 2022 Apr ;11(2):263-271. Epub 2022 Feb 19. PMID: 35510232
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Organosulfur Compounds
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Failure: Acute
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Hepatoprotective
[+]

Hepatoprotective effect of ultrasonicated ginseng berry extract on a rat mild bile duct ligation model.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2019 Oct ;43(4):606-617. Epub 2018 Aug 10. PMID: 31695567
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Ginseng, Ginsenosides
Diseases : Liver Failure: Acute, Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Lactobacillus reuteri improves function of the intestinal barrier in rats with acute liver failure.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrition. 2022 Jul-Aug;99-100:111673. Epub 2022 Apr 1. PMID: 35567844
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Inflammation, Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, NF-kappaB Inhibitor, Nrf2 activation
[+]

Naringenin affords protection against lipopolysaccharide/D-galactosamine-induced acute liver failure.Jan 18, 2022

Pubmed Data : Arch Biochem Biophys. 2022 Jan 19 ;717:109121. Epub 2022 Jan 19. PMID: 35065059
Article Published Date : Jan 18, 2022
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Failure: Acute
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective
[+]

Protective effects of dandelion root extract in experimental acute on chronic liver failure.Mar 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Mar 24 ;10(4). Epub 2021 Mar 24. PMID: 33804908
Article Published Date : Mar 23, 2021
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Liver Failure: Acute
Pharmacological Actions : Antioxidants, Hepatoprotective
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Subchronic treatment with acai frozen pulp prevents the brain oxidative damage in rats with acute liver failure.Jul 13, 2016

Pubmed Data : Metab Brain Dis. 2016 Jul 14. Epub 2016 Jul 14. PMID: 27418003
Article Published Date : Jul 13, 2016
Study Type : Animal Study
Additional Links
Substances : Acai
Diseases : Brain: Oxidative Stress, Liver Failure: Acute
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Asiatic acid exhibits anti-inflammatory and antioxidant activities against lipopolysaccharide and d-galactosamine-induced fulminant hepatic failure.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2017 ;8:785. Epub 2017 Jul 7. PMID: 28736552
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Asiatic Acid
Diseases : Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Curcumin as a therapeutic strategy in liver diseases.Oct 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Oct 17 ;11(10). Epub 2019 Oct 17. PMID: 31627369
Article Published Date : Oct 16, 2019
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Liver Disease, Liver Failure: Acute, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Hepatic protective effects of sulforaphane through the modulation of inflammatory pathways.Mar 31, 2020

Pubmed Data : J Asian Nat Prod Res. 2020 Apr ;22(4):386-396. Epub 2019 Mar 1. PMID: 30821482
Article Published Date : Mar 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage, Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
[+]

N-acetylcysteine for non-acetaminophen induced acute liver failure.Feb 06, 2022

Pubmed Data : Saudi J Gastroenterol. 2022 Feb 7. Epub 2022 Feb 7. PMID: 35142656
Article Published Date : Feb 06, 2022
Study Type : Review
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Liver Damage, Liver Failure: Acute
Pharmacological Actions : Hepatoprotective

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