Liver Failure: Acute

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25 Substances Researched for Liver Failure: Acute
NameACCKFocus
Ginsenosides24Locked
NAC (N-acetyl-L-cysteine)24Locked
Flavonoids13Locked
Geraniol 13Locked
Sulforaphane23Locked
Acai12Locked
Apigenin12Locked
Bacopa12Locked
Bee Venom12Locked
Cannabidiol12Locked
Cannabis12Locked
Chrysin12Locked
Dandelion 12Locked
Diosmetin12Locked
Ginseng12Locked
Ketone Bodies12Locked
Lactobacillus reuteri12Locked
Luteolin12Locked
Naringenin 12Locked
Organosulfur Compounds12Locked
Paeonol12Locked
Schisandra12Locked
Tomatidine 12Locked
Asiatic Acid11Locked
Curcumin11Locked
1 Therapeutic Actions Researched for Liver Failure: Acute
NameACCKFocus
Photobiomodulation110Locked

View the Evidence:
25 Abstracts with Liver Failure: Acute Research

[+]

Effect of intravenous low-intensity laser irradiation of the blood on clinical and laboratory parameters of hepatocellular insufficiency.Aug 31, 2012

Pubmed Data : Bull Exp Biol Med. 2012 Sep ;153(5):754-7. PMID: 23113277
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Diseases : Liver Failure: Acute
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Hepatoprotective
[+]

Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine.Mar 31, 2023

Pubmed Data : Biochem Pharmacol. 2023 Apr ;210:115467. Epub 2023 Feb 26. PMID: 36849063
Article Published Date : Mar 31, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Geraniol
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
[+]

NAC therapy should be considered early in the course of heat injury-mediated ischemic hepatitis.Feb 26, 2019

Pubmed Data : Mil Med. 2019 Feb 27. Epub 2019 Feb 27. PMID: 30811527
Article Published Date : Feb 26, 2019
Study Type : Human: Case Report
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Hepatitis, Liver Failure: Acute
Pharmacological Actions : Cytoprotective
[+]

Pinocembrin ameliorates acute liver failure via activating the Sirt1/PPARα pathway in vitro and in vivo.Jan 14, 2022

Pubmed Data : Eur J Pharmacol. 2022 Jan 15 ;915:174610. Epub 2021 Dec 21. PMID: 34951978
Article Published Date : Jan 14, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

Melittin ameliorates inflammation in mouse acute liver failure via inhibition of PKM2-mediated Warburg effect.Sep 15, 2020

Pubmed Data : Acta Pharmacol Sin. 2020 Sep 16. Epub 2020 Sep 16. PMID: 32939034
Article Published Date : Sep 15, 2020
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Liver Damage, Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
[+]

Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.Apr 30, 2017

Pubmed Data : Int Immunopharmacol. 2017 May ;46:124-132. Epub 2017 Mar 7. PMID: 28282576
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Failure: Acute
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor
[+]

Apigenin has good hepatoprotective effects and potential as a promising therapeutic agent for acute liver failure in clinical application.Jan 10, 2019

Pubmed Data : Int Immunopharmacol. 2019 Jan 11 ;68:171-178. Epub 2019 Jan 11. PMID: 30641432
Article Published Date : Jan 10, 2019
Study Type : Animal Study
Additional Links
Substances : Apigenin, Chrysin, Luteolin
Diseases : Liver Failure: Acute
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Malondialdehyde Down-regulation, Nrf2 activation, Superoxide Dismutase Up-regulation
[+]

Bacopa monnieri extract prevents the neurochemical alterations associated with hepatic encephalopathy.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:535013. Epub 2015 Aug 27. PMID: 26413124
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Hepatic Encephalopathy, Liver Failure: Acute
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice.Dec 23, 2010

Pubmed Data : Br J Pharmacol. 2010 Dec 23. Epub 2010 Dec 23. PMID: 21182490
Article Published Date : Dec 23, 2010
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Cannabis
Diseases : Fulminant Hepatic Failure, Hepatic Encephalopathy, Liver Failure: Acute
Pharmacological Actions : Hepatoprotective, Neuroprotective Agents
[+]

Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure.May 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 May 9 ;8(19):30723-30733. PMID: 28430612
Article Published Date : May 08, 2017
Study Type : Animal Study
Additional Links
Substances : Diosmetin
Diseases : Endotoxemia, Liver Damage, Liver Failure: Acute, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor
[+]

Ginsenoside Rg1 significantly reduces liver damage in an acute liver failure model.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2014 ;2014:538059. Epub 2014 Oct 28. PMID: 25431611
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gomisin A, a compound found within Schisandra, has a protective effect in fulminant liver failure. Jan 01, 2004

Pubmed Data : Asia Pac J Clin Nutr. 2004;13(2):210-6. PMID: 18270473
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Schisandra
Diseases : Fulminant Hepatic Failure, Liver Failure: Acute
[+]

Hepatoprotective effect of diallyl trisulfide against lipopolysaccharide and D-galactosamine induced acute liver failure.Mar 31, 2022

Pubmed Data : Toxicol Res (Camb). 2022 Apr ;11(2):263-271. Epub 2022 Feb 19. PMID: 35510232
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Organosulfur Compounds
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Failure: Acute
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Hepatoprotective
[+]

Hepatoprotective effect of ultrasonicated ginseng berry extract on a rat mild bile duct ligation model.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2019 Oct ;43(4):606-617. Epub 2018 Aug 10. PMID: 31695567
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Ginseng, Ginsenosides
Diseases : Liver Failure: Acute, Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Lactobacillus reuteri improves function of the intestinal barrier in rats with acute liver failure.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrition. 2022 Jul-Aug;99-100:111673. Epub 2022 Apr 1. PMID: 35567844
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Inflammation, Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, NF-kappaB Inhibitor, Nrf2 activation
[+]

Naringenin affords protection against lipopolysaccharide/D-galactosamine-induced acute liver failure.Jan 18, 2022

Pubmed Data : Arch Biochem Biophys. 2022 Jan 19 ;717:109121. Epub 2022 Jan 19. PMID: 35065059
Article Published Date : Jan 18, 2022
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Failure: Acute
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective
[+]

Protective effects of dandelion root extract in experimental acute on chronic liver failure.Mar 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Mar 24 ;10(4). Epub 2021 Mar 24. PMID: 33804908
Article Published Date : Mar 23, 2021
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Liver Failure: Acute
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Subchronic treatment with acai frozen pulp prevents the brain oxidative damage in rats with acute liver failure.Jul 13, 2016

Pubmed Data : Metab Brain Dis. 2016 Jul 14. Epub 2016 Jul 14. PMID: 27418003
Article Published Date : Jul 13, 2016
Study Type : Animal Study
Additional Links
Substances : Acai
Diseases : Brain: Oxidative Stress, Liver Failure: Acute
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure.Aug 31, 2023

Pubmed Data : J Integr Med. 2023 Sep ;21(5):464-473. Epub 2023 Aug 9. PMID: 37620223
Article Published Date : Aug 31, 2023
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Liver Failure: Acute
Pharmacological Actions : Hepatoprotective
[+]

Tomatidine protects against inflammation/oxidative stress-driven fulminant hepatic failure.Mar 29, 2024

Pubmed Data : Int Immunopharmacol. 2024 Mar 30 ;130:111732. Epub 2024 Feb 24. PMID: 38402834
Article Published Date : Mar 29, 2024
Study Type : Animal Study
Additional Links
Substances : Tomatidine
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Liver Failure: Acute, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb.Dec 19, 2022

Pubmed Data : Cell Rep. 2022 Dec 20 ;41(12):111847. PMID: 36543135
Article Published Date : Dec 19, 2022
Study Type : Animal Study
Additional Links
Substances : Ketone Bodies
Diseases : Liver Failure: Acute, Pancreatitis
Pharmacological Actions : Pancreato Protective Agents
[+]

Asiatic acid exhibits anti-inflammatory and antioxidant activities against lipopolysaccharide and d-galactosamine-induced fulminant hepatic failure.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2017 ;8:785. Epub 2017 Jul 7. PMID: 28736552
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Asiatic Acid
Diseases : Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Curcumin as a therapeutic strategy in liver diseases.Oct 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Oct 17 ;11(10). Epub 2019 Oct 17. PMID: 31627369
Article Published Date : Oct 16, 2019
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Liver Disease, Liver Failure: Acute, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Hepatic protective effects of sulforaphane through the modulation of inflammatory pathways.Mar 31, 2020

Pubmed Data : J Asian Nat Prod Res. 2020 Apr ;22(4):386-396. Epub 2019 Mar 1. PMID: 30821482
Article Published Date : Mar 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage, Liver Failure: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
[+]

N-acetylcysteine for non-acetaminophen induced acute liver failure.Feb 06, 2022

Pubmed Data : Saudi J Gastroenterol. 2022 Feb 7. Epub 2022 Feb 7. PMID: 35142656
Article Published Date : Feb 06, 2022
Study Type : Review
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Liver Damage, Liver Failure: Acute
Pharmacological Actions : Hepatoprotective

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