Lung Damage

Name	AC	CK
Flavonoids	9	20
Vitamin D	2	12
Nicotinamide Mononucleotide	4	9
Salvia miltiorrhiza	4	9
Astaxanthin	4	8
Curcumin	3	6
Ginkgo biloba	2	6
Hydrogen: Molecular	3	6
Luteolin	3	6
Urolithin A	2	6
Vitamin C	3	6
Emodin	3	5
Honeysuckle	3	5
Piperlongumine	3	5
Puerarin	2	5
Vitamin E	3	5
Andrographolide	2	4
Astragaloside	2	4
Cordyceps sinensis	2	4
Fucoxanthin	2	4
Garlic	2	4
Hydrogen Water	2	4
Melatonin	2	4
Selenium	2	4
Biochanin A	2	3
Ginsenosides	3	3
Isoflavones	2	3
Licorice	1	3
Tanshinone IIA	2	3
Apigenin	1	2
Arginine	1	2
Artesunate	1	2
Blueberry	1	2
Caffeic acid phenethyl ester	1	2
Capsaicin	1	2
Carbon 60	1	2
Catechin	1	2
Chlorogenic Acid	1	2
Citrus Triterpenoids	1	2
Citrus naringin	1	2
Cordyceps Militaris	1	2
Diallyl sulfide	1	2
EGCG (Epigallocatechin gallate)	1	2
Elecampane	1	2
Fermented Foods and Beverages	1	2
Fucoidan	1	2
Hesperidin	1	2
Icariin	1	2
Indigo Naturalis	1	2
Jujube	1	2
Lutein	1	2
Nigella sativa (aka Black Seed)	1	2
Nobiletin	1	2
Oleuropein	1	2
Organosulfur Compounds	1	2
Paeoniflorin	1	2
Piperine	1	2
Poria cocos	1	2
Propolis: Bee	1	2
Pterostilbene	1	2
Punicalagin	1	2
Reishi Mushroom	1	2
Rose	1	2
Royal Jelly	1	2
Safflower	1	2
Sea Cucumber	1	2
Shikonin	1	2
Tangeretin	1	2
Turmeric	1	2
Vitamin A	1	2
Vitamin K2	1	2
White Tea	1	2
Zataria multiflora	1	2
Berberine	1	1
Bergamot	1	1
Bioflavonoids	1	1
Crocin	1	1
Diosmetin	1	1
Echinacea	1	1
Isoliquiritigenin	1	1
Kaempferol	1	1
Liquiritigenin	1	1
Patchouli	1	1
Perillaldehyde	1	1
Polyphenols	1	1
Procyanidin B2	1	1
Sinomenine	1	1
Thymoquinone	1	1
Vanillin	1	1
Verbascoside	1	1
Verbena officinalis	1	1
Wogonin	1	1

Name	AC	CK
Electronic Cigarettes	14	58
Glyphosate	1	10
Phthalates	1	10
Paraquat	5	9
Polystyrene nanoparticles	3	5
Aluminum	1	2
Benzo(a)pyrene	1	2
Bisphenol A	1	2
Cadmium	1	2
Chlorine	1	2
Lisinopril	1	2
Sodium Fluoride	1	2
Statin Drugs	1	2
Titanium Dioxide	1	2

Name	AC	CK	Focus
Electroacupuncture	4	9

Name	AC	CK	Focus
Nanotechnology	1	2

Diseases : Coronavirus Disease (Covid-19), Lung Damage, Lung Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine.Sep 03, 2019

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Pubmed Data : J Clin Invest. 2019 Sep 4. Epub 2019 Sep 4. PMID: 31483291

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Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:2765354. Epub 2022 Jun 24. PMID: 35783527

Article Published Date : Dec 31, 2021

Study Type : Animal Study, In Vitro Study

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Substances : Flavonoids

Diseases : Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Cryptotanshinone attenuates LPS-induced acute lung injury by regulating metabolic reprogramming of macrophage.Dec 31, 2021

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Pubmed Data : Front Med (Lausanne). 2022 ;9:1075465. Epub 2023 Jan 13. PMID: 36714100

Article Published Date : Dec 31, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Salvia miltiorrhiza

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents

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E-cigarette or vaping induced lung injury: A case series and literature review.Dec 31, 2019

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Pubmed Data : Biochim Biophys Acta Mol Basis Dis. 2024 Aug 30 ;1870(8):167480. Epub 2024 Aug 30. PMID: 39209235

Article Published Date : Aug 29, 2024

Study Type : Animal Study, In Vitro Study

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Diseases : Endotoxemia, Lung Damage

Therapeutic Actions : Electroacupuncture

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Ginkgolide B functions as a determinant constituent of Ginkgolides in alleviating lipopolysaccharide-induced lung injury.Jun 30, 2016

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Pubmed Data : Biomed Pharmacother. 2016 Jul ;81:71-78. Epub 2016 Apr 11. PMID: 27261579

Article Published Date : Jun 30, 2016

Study Type : Animal Study, In Vitro Study

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Substances : Ginkgo biloba

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor

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Ginkgolide C attenuates lipopolysaccharide‑induced acute lung injury.Mar 31, 2021

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Pubmed Data : Int J Mol Med. 2021 Apr ;47(4). Epub 2021 Mar 2. PMID: 33649807

Pubmed Data : Drug Metabol Personal Ther. 2016 Mar 1 ;31(1):47-54. PMID: 26943616

Article Published Date : Feb 29, 2016

Study Type : Animal Study

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Substances : Garlic, Selenium, Vitamin A, Vitamin C, Vitamin E

Diseases : Lung Damage, Lung Diseases

Pharmacological Actions : Antioxidants

Problem Substances : Lisinopril

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A pre-existing respiratory syncytial virus infection predisposes the lung to chlorine induced injury.Jul 31, 2015

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Pubmed Data : Am J Physiol Lung Cell Mol Physiol. 2015 Aug 1 ;309(3):L205-10. Epub 2015 Jun 12. PMID: 26071553

Article Published Date : Jul 31, 2015

Study Type : Animal Study

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Diseases : Lung Damage, Respiratory Syncytial Virus Infections

Additional Keywords : Risk Factors

Problem Substances : Chlorine

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Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Plant Extracts

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Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury.Apr 30, 2016

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Pubmed Data : Acta Pharm Sin B. 2016 May ;6(3):205-11. Epub 2016 Mar 22. PMID: 27175331

Article Published Date : Apr 30, 2016

Study Type : Animal Study

Additional Links

Substances : Andrographolide

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor

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Biochanin A protect against lipopolysaccharide-induced acute lung injury.Dec 31, 2019

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Pubmed Data : Microb Pathog. 2020 Jan ;138:103846. Epub 2019 Nov 4. PMID: 31698051

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Biochanin A

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Both C. longa and curcumin improved paraquat-induced systemic and lung inflammation and oxidative stress.Jun 30, 2022

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Pubmed Data : Avicenna J Phytomed. 2022 Jul-Aug;12(4):414-424. PMID: 35782772

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Pubmed Data : J Biochem Mol Toxicol. 2023 Apr 3:e23352. Epub 2023 Apr 3. PMID: 37010041

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Pubmed Data : Int J Toxicol. 2017 Mar/Apr;36(2):165-173. Epub 2016 Dec 29. PMID: 28033732

Article Published Date : Dec 31, 2016

Study Type : Animal Study

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Diseases : Air Pollution Linked Toxicity, Lung Damage, Lung Inflammation

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Fucoidan may attenuate hyperoxic lung injury via the ERK1/2 signaling pathway.Dec 31, 2017

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Pubmed Data : Mol Med Rep. 2018 Jan ;17(1):1813-1818. Epub 2017 Nov 10. PMID: 29138816

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Fucoidan

Diseases : Hyperoxia, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Fucoxanthin ameliorates oxidative injury and inflammation of human bronchial epithelial cells induced by cigarette smoke.Dec 31, 2022

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Pubmed Data : Oncotarget. 2017 Mar 21 ;8(12):18935-18942. PMID: 28039487

Article Published Date : Mar 20, 2017

Study Type : Animal Study

Additional Links

Substances : Isoflavones

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Green tea polyphenol catechins inhibit coronavirus replication and potentiate the adaptive immunity.Jun 06, 2021

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Pubmed Data : Antioxidants (Basel). 2021 Jun 7 ;10(6). Epub 2021 Jun 7. PMID: 34200327

Article Published Date : Jun 06, 2021

Problem Substances : Paraquat

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Inhaled tire-wear microplastic particles induced pulmonary fibrotic injury via epithelial cytoskeleton rearrangement.Dec 31, 2021

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Pubmed Data : Environ Int. 2022 06 ;164:107257. Epub 2022 Apr 26. PMID: 35486965

Article Published Date : Dec 31, 2021

Study Type : Animal Study

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Diseases : Air Pollution Linked Toxicity, Lung Damage

Additional Keywords : Epigenetic Modification, Microplastic

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Isoalantolactone is a potential therapeutic reagent against inflammation and acute lung injury.Dec 31, 2018

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Pubmed Data : Open Med (Wars). 2019 ;14:827-832. Epub 2019 Nov 7. PMID: 31737787

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Vitamin D

Diseases : Lung Damage, Lung Injury: Smoke-Induced, Pulmonary Emphysema

Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-4 downregulation

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Lung injury induced by bisphenol A is ameliorated by selenium supplementation.Feb 11, 2017

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Pubmed Data : Pathophysiology. 2017 Feb 12. Epub 2017 Feb 12. PMID: 28285737

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Pubmed Data : Biochem Biophys Res Commun. 2023 Jan 29 ;642:118-127. Epub 2022 Dec 5. PMID: 36566563

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Pubmed Data : J Adv Res. 2023 Mar 17. Epub 2023 Mar 17. PMID: 36933884

Article Published Date : Mar 16, 2023

Study Type : Animal Study

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Diseases : Lung Damage, Microplastic Toxicity

Problem Substances : Polystyrene nanoparticles

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Protective effect of Cordyceps sinensis extract on lipopolysaccharide-induced acute lung injury.Jun 27, 2019

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Pubmed Data : Chin J Integr Med. 2023 Feb 27. Epub 2023 Feb 27. PMID: 36843056

Article Published Date : Feb 26, 2023

Study Type : Animal Study

Additional Links

Substances : Cordyceps sinensis

Diseases : Kidney Damage, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents

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Pterostilbene pre-treatment reduces LPS-induced acute lung injury.Nov 30, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Additional Keywords : Natural Substance Synergy

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Tangeretin attenuates acute lung injury in septic mice.Dec 31, 2023

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Pubmed Data : Inflamm Res. 2024 Jan ;73(1):47-63. Epub 2023 Dec 26. PMID: 38147126

Article Published Date : Dec 31, 2023

Study Type : Animal Study

Additional Links

Substances : Tangeretin

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-18 down-regulation, Interleukin-1 beta downregulation

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Tanshinone IIA loaded bioactive nanoemulsion for alleviation of lipopolysaccharide induced acute lung injury.Sep 09, 2022

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Pubmed Data : Toxics. 2024 May 22 ;12(6). Epub 2024 May 22. PMID: 38922058

Article Published Date : May 21, 2024

Study Type : Animal Study

Additional Links

Substances : Reishi Mushroom

Diseases : Cadmium Poisoning , Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents

Problem Substances : Cadmium

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The results show for the first that DADS-induced anti-inflammatory effect in acute pancreatitis is regulated through PPAR-γ.Jan 31, 2022

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Pubmed Data : Inflammation. 2022 Feb ;45(1):45-58. Epub 2022 Jan 21. PMID: 35061151

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Pubmed Data : Toxics. 2023 Sep 4 ;11(9). Epub 2023 Sep 4. PMID: 37755759

Article Published Date : Sep 03, 2023

Study Type : Animal Study

Additional Links

Diseases : Lung Damage

Problem Substances : Electronic Cigarettes

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Titanium dioxide nanoparticles cause acute toxicity, thrombosis, liver, lung and kidney damage when injected into mice. May 01, 2009

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Pubmed Data : J Appl Toxicol. 2009 May;29(4):330-7. PMID: 19156710

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Pubmed Data : Food Chem Toxicol. 2019 Sep ;131:110551. Epub 2019 Jun 1. PMID: 31163217

Pubmed Data : Environ Res. 2016 May ;147:146-58. Epub 2016 Feb 11. PMID: 26874047

Article Published Date : Apr 30, 2016

Study Type : In Vitro Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Lung Damage, Oxidative Stress

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Inhalable textile microplastic fibers impair airway epithelial differentiation. Nov 15, 2023

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Pubmed Data : Am J Respir Crit Care Med. 2023 Nov 16. Epub 2023 Nov 16. PMID: 37971785

Article Published Date : Nov 15, 2023

Study Type : In Vitro Study

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Diseases : Lung Damage, Microplastic Toxicity

[+]

Isoliquiritigenin inhibited the inflammatory of LPS-induced lung injury by activating PPAR-γ and inhibiting NF-κB activation.Jul 31, 2018

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Pubmed Data : Inflammation. 2018 Aug ;41(4):1290-1296. PMID: 29654430

Article Published Date : Jul 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Isoliquiritigenin

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Isosinensetin alleviates the injury of human bronchial epithelial cells induced by PM2.5.Nov 30, 2021

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Protective effect of Lonicera japonica on PM2.5-induced pulmonary damage.Apr 19, 2023

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Pubmed Data : Int J Nanomedicine. 2021 ;16:5117-5131. Epub 2021 Jul 27. PMID: 34349511

Article Published Date : Dec 31, 2020

Study Type : Review

Additional Links

Substances : Thymoquinone

Diseases : Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

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View the Evidence: 173 Abstracts with Lung Damage Research

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A multi-omics investigation of the lung injury induced by PM2.5 at environmental levels via the lung-gut axis.Mar 26, 2024

A preliminary report on pulmonary illness related to E-Cigarette use in illinois and Wisconsin. Sep 05, 2019

Association of phthalate exposure with pulmonary function in adults.Aug 22, 2023

Dietary vitamin D mitigates coronavirus-induced lung inflammation and damage.Dec 14, 2023

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine.Sep 03, 2019

Exposure to glyphosate during glyphosate application had significant effects on oxidative stress and lung function in maize farmers.Jul 13, 2022

First evidence of microplastics isolated in European citizens' lower airway.Jun 22, 2022

The use of e-cigarettes significantly impaired various lung function parameters.Oct 14, 2018

Traffic-related air pollution, biomarkers of metabolic dysfunction, oxidative stress, and CC16 in children.Aug 19, 2021

E-cigarette vapour renders neutrophils dysfunctional due to filamentous actin accumulation.Sep 04, 2023

Electronic cigarette menthol flavoring is associated with increased inhaled micro and sub-micron particles and worse lung function in combustion cigarette smokers.Apr 10, 2023

Polystyrene microplastic particles induce autophagic cell death in BEAS-2B human bronchial epithelial cells.Jan 31, 2023

Baicalin ameliorates radiation-induced lung injury.Dec 31, 2021

Cryptotanshinone attenuates LPS-induced acute lung injury by regulating metabolic reprogramming of macrophage.Dec 31, 2021

E-cigarette or vaping induced lung injury: A case series and literature review.Dec 31, 2019

E-cigarette or vaping product use-associated lung injury (EVALI) in an active duty service member.Oct 02, 2020

E-cigarette or vaping product-use-associated lung injury (EVALI): A case report of a pneumonia mimic with severe leukocytosis and weight loss.Jan 31, 2020

Electroacupuncture pretreatment maintains mitochondrial quality control via HO-1/MIC60 signaling pathway to alleviate endotoxin-induced acute lung injury.Aug 29, 2024

Ginkgolide B functions as a determinant constituent of Ginkgolides in alleviating lipopolysaccharide-induced lung injury.Jun 30, 2016

Ginkgolide C attenuates lipopolysaccharide‑induced acute lung injury.Mar 31, 2021

Liquiritin exhibits anti-acute lung injury activities.Apr 02, 2023

Lung transplantation for the treatment of vaping induced, irreversible, end stage lung injury. Oct 28, 2020

Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury.Nov 30, 2024

Puerarin ameliorates acute lung injury by modulating NLRP3 inflammasome-induced pyroptosis.Aug 17, 2022

Urolithin A attenuates ferroptosis in lipopolysaccharide-induced acute lung injury.Dec 31, 2022

Urolithin A exerts a protective effect on lipopolysaccharide-induced acute lung injury.Feb 05, 2024

The regulation of circRNA_kif26b on alveolar epithelial cell senescence via miR-346-3p is involved in microplastics-induced lung injuries Jul 14, 2023

A combination of GAR and S-VACE can be a novel therapy for the management of lung diseases in humans.Feb 29, 2016

A pre-existing respiratory syncytial virus infection predisposes the lung to chlorine induced injury.Jul 31, 2015

A statin drug exhibits toxicity in the animal model. May 01, 1994

Ambient particle matter in the urban area of Hangzhou can significantly cause lung inflammatory injury in rats.Apr 07, 2018

Ameliorative effect of gossypin against acute lung injury in experimental sepsis.Mar 14, 2019

Analysis of the protective effects of Rosa roxburghii-fermented juice on lipopolysaccharide-induced acute lung injury.Apr 29, 2024

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury.Apr 30, 2016

Andrographolide sulfonate attenuates acute lung injury.Dec 31, 2017

Anti-inflammatory effects of anethole in lipopolysaccharide-induced acute lung injury.Dec 04, 2013

Antioxidant property of the Egyptian propolis extract on aluminum silicate intoxication.Dec 09, 2020

Apigenin suppresses innate immune responses and ameliorates lipopolysaccharide-induced inflammation.Dec 31, 2023

Artesunate reduces sepsis-mediated acute lung injury in a SIRT1-dependent manner.Dec 31, 2022

Assessment on the lung injury of mice posed by airborne PM 2.5 collected from developing area in China.Aug 16, 2021

Astaxanthin ameliorates lipopolysaccharide-induced acute lung injury.Oct 23, 2022

Astaxanthin attenuates cigarette smoke-induced small airway remodeling via the AKT1 signaling pathwayMar 29, 2024

Astaxanthin attenuates ferroptosis via Keap1-Nrf2/HO-1 signaling pathways in LPS-induced acute lung injury.Oct 13, 2022

Astaxanthin protects ochratoxin -induced lung injury in mice through the Nrf2/NF-κB pathway.Sep 16, 2019

Astragaloside IV pre-treatment attenuates PM2.5-induced lung injury.Dec 26, 2021

Baicalin ameliorates lung injury.Dec 31, 2022

Baicalin inhibits inflammation of lipopolysaccharide-induced acute lung injury.Dec 31, 2021

Beneficial effect of Indigo Naturalis on acute lung injury induced by influenza A virus.Dec 20, 2020

Biochanin A protect against lipopolysaccharide-induced acute lung injury.Dec 31, 2019

Both C. longa and curcumin improved paraquat-induced systemic and lung inflammation and oxidative stress.Jun 30, 2022

Caffeic acid phenethyl ester ameliorates pulmonary inflammation and apoptosis reducing Nf-κβ activation in blunt pulmonary contusion model.Jul 31, 2019

Capsaicin protects against lipopolysaccharide-induced acute lung injury.Dec 31, 2020

Chlorogenic acid protective effects on paraquat-induced pulmonary oxidative damage and fibrosis.Apr 02, 2023

Cordycepin induces M1/M2 macrophage polarization to attenuate the liver and lung damage and immunodeficiency in immature mice with sepsis.Nov 26, 2021

Cryptotanshinone alleviates radiation-induced lung fibrosis.Jul 09, 2023

Curcumin protects against cigarette smoke and ethanol-induced lipid alterations in rat lung and liver.Jun 01, 2009

Diallyl sulfide may have protective effect on acute lung injury induced by paraquat.Jun 19, 2021

Dihydrotanshinone attenuates LPS-induced acute lung injury.Jan 31, 2022

Effects of piperlonguminine on lung injury in severe acute pancreatitis. Mar 19, 2023

EGCG improved lung damage in P. aeruginosa infection by inhibiting the production.Dec 31, 2021

Electroacupuncture alleviates lung injury.Dec 31, 2022

Electroacupuncture preconditioning alleviates lipopolysaccharides-induced acute lung injury.Dec 31, 2021

Electroacupuncture pretreatment protects septic rats from acute lung injury.Aug 29, 2022

Emodin ameliorates severe acute pancreatitis-associated acute lung injury.Dec 31, 2022

Emodin protects against lipopolysaccharide-induced acute lung injury.Dec 31, 2021

Fine particulate matter and sulfur dioxide coexposures induce rat lung pathological injury and inflammatory responses.Dec 31, 2016

Fucoidan may attenuate hyperoxic lung injury via the ERK1/2 signaling pathway.Dec 31, 2017

Fucoxanthin ameliorates oxidative injury and inflammation of human bronchial epithelial cells induced by cigarette smoke.Dec 31, 2022

Fucoxanthin decreases lipopolysaccharide-induced acute lung injury.May 25, 2022

Fullerene C60 has strong biological activity that it might be an effective approach for lung damage.Aug 25, 2023

Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury.Apr 11, 2024

Glabridin attenuates lipopolysaccharide-induced acute lung injury.Mar 20, 2017

Lung Damage

View the Evidence:
173 Abstracts with Lung Damage Research