Lupus Erythematosus: Systemic

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54 Substances Researched for Lupus Erythematosus: Systemic
NameACCKFocus
Vitamin D15135Locked
DHEA (Dehydroepiandrosterone)480Locked
Omega-3 Fatty Acids441Locked
DHA (Docosahexaenoic Acid)332Locked
Indole-3-Carbinol332Locked
EPA (Eicosapentaenoic Acid)230Locked
Fish Oil424Locked
Vitamin E221Locked
Vitamin B12120Locked
Green Tea212Locked
Apples110Locked
Astragalus110Locked
Calcium110Locked
Gentian110Locked
Oranges110Locked
Pine Bark Extract110Locked
Polyphenols110Locked
Red Wine Extract110Locked
Royal Jelly110Locked
Tea110Locked
Tryptophan110Locked
Paeoniflorin46Locked
Curcumin45Locked
Guduchi 13Locked
Melatonin33Locked
Antrodia camphorata12Locked
Apigenin12Locked
Ashwagandha12Locked
Bupleurum12Locked
Cordyceps sinensis12Locked
Coumestrol12Locked
Emodin12Locked
Fisetin12Locked
Flavonoids12Locked
Genistein12Locked
Gingerol 12Locked
Isoflavones12Locked
Lactobacillus fermentum12Locked
Lactobacillus paracasei12Locked
Lotus 12Locked
Mangosteen12Locked
Olive Oil12Locked
Probiotics22Locked
Reishi Mushroom12Locked
Resveratrol22Locked
Sophora Flavescens12Locked
Soy12Locked
Turmeric12Locked
Wormwood12Locked
phytoestrogens12Locked
Celastrol11Locked
Mussel: Green-lipped (Perna canaliculus)11Locked
Piperine11Locked
Polyunsaturated Fatty Acids (PUFAs)11Locked
14 Problem Substances Researched for Lupus Erythematosus: Systemic
NameACCKFocus
Statin Drugs220Locked
Bisphenol A 15Locked
Freund adjuvant24Locked
Pristane24Locked
Atorvastatin13Locked
Gliadin13Locked
Simvastatin13Locked
Wheat13Locked
Adjuvant12Locked
Aluminum Hydroxide12Locked
Hexadecane12Locked
Mineral Oil12Locked
Squalene12Locked
Squalene, Adjuvant12Locked
7 Therapeutic Actions Researched for Lupus Erythematosus: Systemic
NameACCKFocus
Light Therapy211Locked
Sunlight exposure211Locked
Exercise110Locked
Exercise: Aerobic110Locked
Exercise: Resistance Training110Locked
Hyperbaric Treatment13Locked
Microbiota Transfer Therapy11Locked
12 Problematic Actions Researched for Lupus Erythematosus: Systemic
NameACCKFocus
Vaccination: All747Locked
Vaccination: Hepatitis B636Locked
Vaccination: HPV (Gardasil)37Locked
Vaccination: Tetanus24Locked
Vaccination: Diphtheria-Pertussis-Tetanus11Locked
Vaccination: Haemophilus Influenzae11Locked
Vaccination: Influenza11Locked
Vaccination: Lyme disease11Locked
Vaccination: Mumps-Measles-Rubella (MMR)11Locked
Vaccination: Rabies11Locked
Vaccination: Rotavirus11Locked
Vaccination: Varicella (Chicken pox)11Locked
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View the Evidence:
121 Abstracts with Lupus Erythematosus: Systemic Research

[+]

Efficacy and safety of total glucosides of paeony in the treatment of systemic lupus erythematosus.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:932874. Epub 2022 Dec 7. PMID: 36569311
Article Published Date : Dec 31, 2021
Study Type : Meta Analysis, Review
Additional Links
Substances : Peony
Diseases : Systemic Lupus Erythematosus
Additional Keywords : Medication Reduction
[+]

Serum homocysteine levels were higher and vitamin B12 levels were lower among individuals with systemic lupus erythematosus.Jul 22, 2020

Pubmed Data : J Am Coll Nutr. 2020 Jul 23:1-11. Epub 2020 Jul 23. PMID: 32702250
Article Published Date : Jul 22, 2020
Study Type : Meta Analysis
Additional Links
Substances : Vitamin B12
Diseases : Homocysteine: Elevated, Lupus Erythematosus: Systemic, Vitamin B 12 Deficiency
Additional Keywords : Risk Factors
[+]

This study suggests that vaccinations are related to increased risks of systemic lupus erythematosus and rheumatoid arthritis.Jun 30, 2017

Pubmed Data : Autoimmun Rev. 2017 Jul ;16(7):756-765. Epub 2017 May 5. PMID: 28483543
Article Published Date : Jun 30, 2017
Study Type : Meta Analysis, Review
Additional Links
Diseases : Rheumatoid Arthritis, Systemic Lupus Erythematosus, Vaccine-induced Toxicity
[+]

Vitamin D supplementation reduced anti-dsDNA positivity on systemic lupus erythematosus and could possibly reduce rheumatoid arthritis recurrence.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2017 Jun ;96(23):e7024. PMID: 28591033
Article Published Date : May 31, 2017
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Rheumatoid Arthritis, Systemic Lupus Erythematosus
[+]

Astragalus injection may be a useful approach for enhancing the efficacy of system lupus erythematoosus treatment. May 01, 2006

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 May;26(5):443-5. PMID: 16883914
Article Published Date : May 01, 2006
Study Type : Human Study
Additional Links
Substances : Astragalus
Diseases : Lupus Erythematosus: Systemic
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Combined aerobic and resistance training improves physical and executive functions in women with systemic lupus erythematosus.Mar 02, 2021

Pubmed Data : Lupus. 2021 Mar 3:961203321998749. Epub 2021 Mar 3. PMID: 33657920
Article Published Date : Mar 02, 2021
Study Type : Human Study
Additional Links
Diseases : Systemic Lupus Erythematosus
Therapeutic Actions : Exercise: Aerobic, Exercise: Resistance Training
[+]

Daily consumption of green tea extracts for 12 weeks improves the systemic lupus erythematosus disease activity as well as some aspects of quality of life.Jul 01, 2017

Pubmed Data : Phytother Res. 2017 Jul ;31(7):1063-1071. Epub 2017 Jun 6. PMID: 28585735
Article Published Date : Jul 01, 2017
Study Type : Human Study
Additional Links
Substances : Green Tea, Tea
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Deficiency of 25(OH)D3, a potentially modifiable risk factor, independently predicted cognitive impairment in SLE patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(12):e0144149. Epub 2015 Dec 4. PMID: 26636681
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Systemic Lupus Erythematosus, Vitamin D Deficiency
Additional Keywords : Risk Factors, Risk Reduction, Supplementation
[+]

DHEA improves symptoms of systemic lupus erythematosus. Dec 01, 1998

Pubmed Data : J Rheumatol. 1998 Dec;25(12):2352-6. PMID: 9858429
Article Published Date : Dec 01, 1998
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

DHEA is well tolerated, clinically beneficial and reduces the need for prednisone in patients with systemic lupus erythematosus. Apr 18, 2007

Pubmed Data : J Agric Food Chem. 2007 Apr 18;55(8):2816-23. Epub 2007 Mar 24. PMID: 9489820
Article Published Date : Apr 18, 2007
Study Type : Human Study
Additional Links
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
Additional Keywords : Drug Sparing
[+]

DHEA is well-tolerated and significantly reduces the number of SLE flares in women with mild-to-moderate systemic lupus erythematosus. Nov 01, 2002

Pubmed Data : Arthritis Rheum. 2002 Nov;46(11):2924-7. PMID: 12428233
Article Published Date : Nov 01, 2002
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

DHEA significantly reduces serum levels of proinflammatory cytokines in women witih systemic lupus erythematosus. Dec 01, 2004

Pubmed Data : Ann Rheum Dis. 2004 Dec;63(12):1623-6. PMID: 15547086
Article Published Date : Dec 01, 2004
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

DHEA supplementation improves symptoms in patients with system lupus erythematosus. Sep 01, 1994

Pubmed Data : Arthritis Rheum. 1994 Sep;37(9):1305-10. PMID: 7945493
Article Published Date : Sep 01, 1994
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

EPA and DHA have therapeutic value in the treatment of systemic lupus erythmeatosus. Mar 01, 1997

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 1997 Mar;56(3):193-8. PMID: 9089797
Article Published Date : Mar 01, 1997
Study Type : Human Study
Additional Links
Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid)
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

EPA and DHA induces prolonged remission of systemic lupus erythematosus without side effects. Sep 01, 1994

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 1994 Sep;51(3):207-13. PMID: 7824535
Article Published Date : Sep 01, 1994
Study Type : Human Study
Additional Links
Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid)
Diseases : Lupus Erythematosus: Systemic
[+]

Exercise training can attenuate the inflammatory milieu in women with systemic lupus erythematosus.Sep 14, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Appl Physiol (1985). 2014 Sep 15 ;117(6):639-47. Epub 2014 Jul 18. PMID: 25038103
Article Published Date : Sep 14, 2014
Study Type : Human Study
Additional Links
Diseases : Systemic Lupus Erythematosus
Therapeutic Actions : Exercise
Pharmacological Actions : Immunomodulatory
[+]

Gentian improves outcome in patients with systemic lupus erythemaatous treated with prednisone. Mar 01, 1989

Pubmed Data : Zhong Xi Yi Jie He Za Zhi. 1989 Mar;9(3):156-7, 133-4. PMID: 2736700
Article Published Date : Mar 01, 1989
Study Type : Human Study
Additional Links
Substances : Gentian
Diseases : Lupus Erythematosus: Systemic
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Hepatitis B vaccination is associated with a wide range of autoimmune diseases.Feb 01, 2006

Pubmed Data : Clin Chim Acta. 2006 Feb;364(1-2):196-204. Epub 2005 Aug 10. PMID: 15638050
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Diseases : Arthritis, Arthritis: Rheumatoid, Autoimmune Diseases, Glomerulonephritis, Guillain-Barre Syndrome, Multiple Sclerosis, Myelitis, Optic Neuritis, Pancytopenia, Systemic Lupus Erythematosus, Thrombocytopenia
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

Hepatitis B vaccination significantly increases the risk of a wide range of autoimmune diseases.Jun 01, 2005

Pubmed Data : Autoimmunity. 2005 Jun;38(4):295-301. PMID: 16206512
Article Published Date : Jun 01, 2005
Study Type : Human Study
Additional Links
Diseases : Alopecia, Arthritis, Hepatitis B , Lupus Erythematosus: Systemic, Optic Neuritis, Rheumatoid Arthritis, Thrombocytopenia, Vasculitis
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

In patients with systemic lupus erythematosus low vitamin D was associated with a higher disease activity and an increase in serum vitamin D was associated with reduced disease activity over time.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lupus Sci Med. 2015 ;2(1):e000064. Epub 2015 Apr 8. PMID: 25893106
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Autoimmune Diseases, Systemic Lupus Erythematosus, Vitamin D Deficiency
Additional Keywords : Diseases that are Linked, Significant Treatment Outcome
[+]

Indole-3 carbinol may be beneficial in the treatment of systemic lupus erythematosus. Jan 01, 2001

Pubmed Data : Lupus. 2001;10(11):779-83. PMID: 11789487
Article Published Date : Jan 01, 2001
Study Type : Human Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

Indole-3-carbinol could modulate the gene expression involved in wound healing in systemic lupus erythematosus cases and healthy controls.Jun 30, 2020

Pubmed Data : Lupus. 2020 Jul ;29(8):954-963. Epub 2020 Jun 9. PMID: 32517571
Article Published Date : Jun 30, 2020
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Systemic Lupus Erythematosus, Wound Healing
Additional Keywords : Gene Expression Regulation
[+]

Omega-3 Fatty Acids improve symptoms of systemic lupus erythematosus and may improve cardiovascular function.Jun 01, 2008

Pubmed Data : Ann Rheum Dis. 2008 Jun;67(6):841-8. Epub 2007 Sep 17. PMID: 17875549
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

Omega-3 fish oil reduces the severity of symptoms in patients with systemic lupus erythematosus. Aug 01, 2004

Pubmed Data : J Rheumatol. 2004 Aug;31(8):1551-6. PMID: 15290734
Article Published Date : Aug 01, 2004
Study Type : Human Study
Additional Links
Substances : Fish Oil, Omega-3 Fatty Acids
Diseases : Lupus Erythematosus: Systemic
[+]

Pcynogenol significantly reduces severity of symptoms in patients with systemic lupus erythematosus. Dec 01, 2001

Pubmed Data : Phytother Res. 2001 Dec;15(8):698-704. PMID: 11746863
Article Published Date : Dec 01, 2001
Study Type : Human Study
Additional Links
Substances : Pine Bark Extract
Diseases : Lupus Erythematosus: Systemic
[+]

Proton pump inhibitors induce changes in the gut microbiome composition of systemic lupus erythematosus patients.Apr 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Microbiol. 2022 Apr 27 ;22(1):117. Epub 2022 Apr 27. PMID: 35477382
Article Published Date : Apr 26, 2022
Study Type : Human Study
Additional Links
Diseases : Systemic Lupus Erythematosus
[+]

Specific changes in vitamin D and calcium homeostasis in SLE patients may be responsible for the severity of symptoms. Aug 30, 2016

Pubmed Data : Clin Exp Rheumatol. 2016 Aug 31. Epub 2016 Aug 31. PMID: 27608168
Article Published Date : Aug 30, 2016
Study Type : Human Study
Additional Links
Substances : Calcium, Vitamin D
Diseases : Calcium Homeostasis: Impairment, Systemic Lupus Erythematosus, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Statin drug use is associated with a Lupus-Like syndrome. Aug 23, 2011

Pubmed Data : Semin Arthritis Rheum. 2011 Aug 23. Epub 2011 Aug 23. PMID: 21868063
Article Published Date : Aug 23, 2011
Study Type : Human Study
Additional Links
Diseases : Lupus-Like Syndrome, Statin-Induced Pathologies, Systemic Lupus Erythematosus
Problem Substances : Statin Drugs
[+]

Statin-induced lupus has been identified within a nationwide pharmacovigilance database.Feb 14, 2012

Pubmed Data : Lupus. 2012 Feb 14. Epub 2012 Feb 14. PMID: 22333565
Article Published Date : Feb 14, 2012
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Toxicity , Lupus Erythematosus: Systemic, Lupus-Like Syndrome
Problem Substances : Statin Drugs
[+]

Systemic lupus erythematosus patients given fish oil supplementation demonstrated improvement in their PGA, RAND SF-36, and circulating inflammatory markers.Dec 31, 2014

Pubmed Data : Nutr J. 2015 ;14(1):82. Epub 2015 Aug 18. PMID: 26283629
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Fish Oil, Omega-3 Fatty Acids
Diseases : Fatigue, Quality of Life: Poor, Systemic Lupus Erythematosus
Additional Keywords : Significant Treatment Outcome
[+]

Systemic lupus erythematosus patients may have lower serontin levels due to enhanced tryptophan degradation associated with their condition.Apr 01, 2000

Pubmed Data : Immunobiology. 2000 Apr;201(5):621-30. PMID: 10834318
Article Published Date : Apr 01, 2000
Study Type : Human Study
Additional Links
Substances : Tryptophan
Diseases : Systemic Lupus Erythematosus
[+]

Systemic lupus erythematosus related to hepatitis B vaccine has been reported.Nov 01, 2009

Pubmed Data : Lupus. 2009 Nov;18(13):1192-7. PMID: 19880567
Article Published Date : Nov 01, 2009
Study Type : Human Study
Additional Links
Diseases : Systemic Lupus Erythematosus
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

The association between common foods, such as oranges and apples, with specific microorganisms reported to be decreased in SLE could be of great importance for these patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 ;7(2):1301-17. Epub 2015 Feb 16. PMID: 25690419
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Apples, Oranges, Polyphenols, Red Wine Extract
Diseases : Dysbiosis, Systemic Lupus Erythematosus
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Microbiota
[+]

The decrease of vitamin D level is related to the disease activity of SLE patients.Oct 17, 2021

Pubmed Data : Beijing Da Xue Xue Bao Yi Xue Ban. 2021 Oct 18 ;53(5):938-941. PMID: 34650298
Article Published Date : Oct 17, 2021
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Systemic Lupus Erythematosus, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

These results showed improvements with 3-month royal jelly treatment in regard to the clinical severity score and laboratory markers for the disease.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2016 ;60:32963. Epub 2016 Nov 24. PMID: 27887663
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Royal Jelly
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory
[+]

These results suggest a potential role for vitamin D in systemic lupus erythematosus-related endothelial dysfunction.Sep 30, 2015

Pubmed Data : Am J Med Sci. 2015 Oct ;350(4):302-7. PMID: 26351776
Article Published Date : Sep 30, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Endothelial Dysfunction, Lupus Erythematosus: Systemic
[+]

Ultraviolet B decreases DNA methylation level of CD4+ T cells in patients with systemic lupus erythematosus.Mar 31, 2017

Pubmed Data : Inflammopharmacology. 2017 Apr ;25(2):203-210. Epub 2017 Feb 11. PMID: 28190128
Article Published Date : Mar 31, 2017
Study Type : Human In Vitro, Human Study
Additional Links
Diseases : Systemic Lupus Erythematosus
Therapeutic Actions : Light Therapy, Sunlight exposure
Additional Keywords : DNA Methylation
[+]

Vaccination can precipitate lupus erythematosus.Dec 01, 1999

Pubmed Data : Semin Arthritis Rheum. 1999 Dec;29(3):131-9. PMID: 10622677
Article Published Date : Dec 01, 1999
Study Type : Human Study
Additional Links
Diseases : Systemic Lupus Erythematosus, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
[+]

Vitamin D can positively modulate endothelial function in patients with stable SLE.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 ;6:22341. Epub 2016 Mar 1. PMID: 26930567
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Cardiovascular Disease: Prevention, Systemic Lupus Erythematosus
[+]

Vitamin D deficiency could have a significant impact on cognitive performance in patients with systemic lupus erythematosus.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Innov Clin Neurosci. 2018 Oct 1 ;15(9-10):25-29. PMID: 30588363
Article Published Date : Sep 30, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Cognitive Decline/Dysfunction, Systemic Lupus Erythematosus, Vitamin D Deficiency
Additional Keywords : Increased Risk
[+]

Vitamin D deficiency is common in juvenile systemic lupus erythematosus.Sep 12, 2020

Pubmed Data : Lupus. 2020 Sep 13:961203320957721. Epub 2020 Sep 13. PMID: 32924829
Article Published Date : Sep 12, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Systemic Lupus Erythematosus, Vitamin D Deficiency
Additional Keywords : Increased Risk
[+]

Vitamin D deficiency is highly prevalent in patients with SLE. Feb 24, 2016

Pubmed Data : Lupus. 2016 Feb 25. Epub 2016 Feb 25. PMID: 26921268
Article Published Date : Feb 24, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Lupus Erythematosus: Systemic, Vitamin D Deficiency
[+]

Vitamin D supplementation may be beneficial to patients with systemic lupus erythematosus. Feb 01, 2008

Pubmed Data : Am J Med Sci. 2008 Feb;335(2):99-104. PMID: 18277116
Article Published Date : Feb 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

Vitamin E supplementation may reduce oxidative DNA damage and autoantibody production in systemic lupus eryhematosus. Mar 20, 2008

Pubmed Data : Nat Prod Res. 2008 Mar 20;22(5):422-7. PMID: 17143589
Article Published Date : Mar 20, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin E
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

Winter lupus flares are associated with low vitamin D levels.Feb 28, 2015

Pubmed Data : Clin Exp Rheumatol. 2015 Mar-Apr;33(2):153-8. Epub 2015 Jan 29. PMID: 25664429
Article Published Date : Feb 28, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Systemic Lupus Erythematosus, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Structural alterations in DNA by BPA, generate neo-epitopes that may be a factor responsible for the induction of anti-DNA autoantibodies in SLE.Oct 25, 2019

Pubmed Data : Autoimmunity. 2019 Oct 26:1-9. Epub 2019 Oct 26. PMID: 31656085
Article Published Date : Oct 25, 2019
Study Type : Animal Study, Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity, Systemic Lupus Erythematosus
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
[+]

A temporal association between immunization with HPV vaccine and the appearance of a spectrum of systemic lupus erythematosus like conditions is reported.Aug 31, 2013

Pubmed Data : Clin Rheumatol. 2013 Sep ;32(9):1301-7. Epub 2013 Apr 28. PMID: 23624585
Article Published Date : Aug 31, 2013
Study Type : Human: Case Report
Additional Links
Diseases : Autoimmune Diseases, Systemic Lupus Erythematosus, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: HPV (Gardasil)
[+]

Ayurvedic management of systemic lupus erythematosus overlap vasculitis.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ayurveda Integr Med. 2019 Oct - Dec;10(4):294-298. Epub 2019 Aug 14. PMID: 31421962
Article Published Date : Nov 30, 2019
Study Type : Human: Case Report
Additional Links
Substances : Guduchi
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Ulcer Agents
[+]

Gluten sensitivity has been mistaken for Systemic Lupus Erythematosus. Nov 01, 2004

Pubmed Data : Ann Rheum Dis. 2004 Nov ;63(11):1501-3. PMID: 15479903
Article Published Date : Nov 01, 2004
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease, Gluten Sensitivity, Systemic Lupus Erythematosus
Additional Keywords : Diseases that are Linked
Problem Substances : Gliadin, Wheat
[+]

Hyperbaric oxygen therapy may have a therapeutic role in treating refractory vasculitic ulcer of the toe in an adolescent from systemic lupus erythematosus.Oct 31, 2010

Pubmed Data : Ital J Pediatr. 2010 Oct 31;36(1):72. Epub 2010 Oct 31. PMID: 21040521
Article Published Date : Oct 31, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Systemic Lupus Erythematosus, Vasculitis
Therapeutic Actions : Hyperbaric Treatment
[+]

Obsessive-compulsive symptoms may be a manifestation of neuropsychiatric systemic lupus erythematosus.Jan 01, 2008

Pubmed Data : J Formos Med Assoc. 2008 Jan;107(1):68-72. PMID: 18218580
Article Published Date : Jan 01, 2008
Study Type : Human: Case Report
Additional Links
Diseases : Obsessive-Compulsive Disorder, Systemic Lupus Erythematosus
Additional Keywords : Diseases that are Linked
[+]

Possible systemic lupus erythematosus following HPV immunization has been reported.Jan 01, 2012

Pubmed Data : Lupus. 2012 ;21(2):158-61. PMID: 22235047
Article Published Date : Jan 01, 2012
Study Type : Human: Case Report
Additional Links
Diseases : Lupus Erythematosus: Systemic, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: HPV (Gardasil)
[+]

Simvastatin-induced lupus erythematosus has been reported. Sep 01, 1998

Pubmed Data : South Med J. 1998 Sep ;91(9):873-4. PMID: 9743064
Article Published Date : Sep 01, 1998
Study Type : Human: Case Report
Additional Links
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
[+]

Statin drug induced lupus-like syndrome concomitant with a severe autoimmune hepatitis has been reported. Jan 01, 2003

Pubmed Data : Lupus. 2003 ;12(5):409-12. PMID: 12765306
Article Published Date : Jan 01, 2003
Study Type : Human: Case Report
Additional Links
Diseases : Hepatitis, Systemic Lupus Erythematosus
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Atorvastatin
[+]

Systemic lupus erythematosus has been triggered by hepatitis B vaccine.Aug 01, 2010

Pubmed Data : Clin Nephrol. 2010 Aug;74(2):150-3. PMID: 20630136
Article Published Date : Aug 01, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Systemic Lupus Erythematosus
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

This describes four cases of auto-immune reactions after tetanus vaccination. Jul 18, 2016

Pubmed Data : Immunol Res. 2016 Jul 19. Epub 2016 Jul 19. PMID: 27435706
Article Published Date : Jul 18, 2016
Study Type : Human: Case Report
Additional Links
Diseases : Antiphospholipid Syndrome, Autoimmune Diseases, Dermatomyositis, Diabetes Mellitus: Type 1, Systemic Lupus Erythematosus
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: Tetanus
[+]

A casein-free diet may be of benefit to patients with systemic lupus erythematosus. Jun 01, 1987

Pubmed Data : J Rheumatol Suppl. 1987 Jun;14 Suppl 13:158-65. PMID: 3497268
Article Published Date : Jun 01, 1987
Study Type : Animal Study
Additional Links
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
Additional Keywords : Casein-Free Diet
[+]

A compound found within Lotus flower may positively modulate immune function in autoimmune disease like systemic lupus erythematosus. Feb 15, 2006

Pubmed Data : Eur J Pharmacol. 2006 Feb 15;531(1-3):270-9. Epub 2006 Jan 17. PMID: 16413531
Article Published Date : Feb 15, 2006
Study Type : Animal Study
Additional Links
Substances : Lotus
Diseases : Lupus Erythematosus: Systemic
[+]

A soy diet accelerates renal damage in mice with lupus. Apr 01, 2010

Pubmed Data : J Biol Rhythms. 2010 Apr;25(2):113-22. PMID: 16039550
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Soy
Diseases : Lupus Erythematosus: Systemic, Lupus Nephritis
[+]

Antineutrophil properties of natural gingerols in models of lupus.Jan 07, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JCI Insight. 2021 02 8 ;6(3). Epub 2021 Feb 8. PMID: 33373329
Article Published Date : Jan 07, 2021
Study Type : Animal Study
Additional Links
Substances : Gingerol
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Phytotherapy
[+]

Antrodia camphorata attenuates the progression of nephritis in systemic lupus erythematosus-prone mice. Sep 02, 2008

Pubmed Data : Evid Based Complement Alternat Med. 2008 Sep 2. PMID: 18955361
Article Published Date : Sep 02, 2008
Study Type : Animal Study
Additional Links
Substances : Antrodia camphorata
Diseases : Lupus Erythematosus: Systemic, Lupus Nephritis
[+]

Apigenin, a dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation in mice. Jan 01, 2009

Pubmed Data : Arthritis Res Ther. 2009;11(2):R59. Epub 2009 Apr 30. PMID: 19405952
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Autoimmune Diseases, Lupus Erythematosus: Systemic
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
[+]

Ashwaganda has therapeutic properties in a pristane-induced model of systemic lupus erythematosus. Dec 13, 2011

Pubmed Data : Inflammopharmacology. 2011 Dec 13. Epub 2011 Dec 13. PMID: 22160928
Article Published Date : Dec 13, 2011
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Lupus Erythematosus: Systemic
[+]

Bupleurum polysaccharides have a beneficial effect on system lupus erythematosus-like syndrome in a mouse experimental model. Feb 01, 2005

Pubmed Data : Taehan Kanho Hakhoe Chi. 2005 Feb;35(1):135-42. PMID: 19467314
Article Published Date : Feb 01, 2005
Study Type : Animal Study
Additional Links
Substances : Bupleurum
Diseases : Lupus Erythematosus: Systemic
[+]

Cordyceps attenuates disease severity of lupus in mice. Jun 01, 2010

Pubmed Data : West Indian Med J. 2010 Jun;59(3):245-8. PMID: 19350364
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Cordyceps sinensis
Diseases : Lupus Erythematosus: Systemic
[+]

DHA supplementation impeded IFN and chemokine gene expression associated with lupus flaring and nephritis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2019 ;10:2851. Epub 2019 Dec 13. PMID: 31921124
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Autoimmune Diseases, Nephritis, Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory
[+]

Effects of Astragalus membranaceus on systemic lupus erythematosus in a mouse model of pregnancy.May 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Immun Inflamm Dis. 2022 Jun ;10(6):e624. PMID: 35634952
Article Published Date : May 31, 2022
Study Type : Animal Study
Additional Links
Substances : Astragalus
Diseases : Pregnancy Complications, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation
[+]

Emodin ameliorates renal injury in BXSB mice by modulating TNF-α/ICAM-1.Jan 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2020 09 30 ;40(9). PMID: 32910199
Article Published Date : Jan 29, 2020
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Kidney Damage, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Extra virgin olive oil is a beneficial functional food exerting a preventive/palliative role in the management of systemic lupus erythematosus.Dec 31, 2015

Pubmed Data : J Nutr Biochem. 2016 Jan ;27:278-88. Epub 2015 Oct 29. PMID: 26525667
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-3 (MMP-3) inhibitor, NF-kappaB Inhibitor, Prostaglandin PGE2 downregulation, Renoprotective
[+]

Fisetin inhibits pristine-induced systemic lupus erythematosus in a murine model through CXCLs regulation.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2018 Dec ;42(6):3220-3230. Epub 2018 Oct 1. PMID: 30272314
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Fisetin, Flavonoids
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fish oil supplementation and caloric restriction delay the onset of lupus disease and increase life span in mice. Sep 01, 2004

Pubmed Data : J Clin Immunol. 2004 Sep;24(5):471-80. PMID: 15359106
Article Published Date : Sep 01, 2004
Study Type : Animal Study
Additional Links
Substances : Fish Oil
Diseases : Lupus Erythematosus: Systemic
[+]

Fish oil supplementation and energy restriction protect against renal deterioration and oxidative damage in lupus-prone mice. Sep 01, 2005

Pubmed Data : Biochem Pharmacol. 2005 Sep 1;70(5):700-13. PMID: 16022752
Article Published Date : Sep 01, 2005
Study Type : Animal Study
Additional Links
Substances : Fish Oil
Diseases : Lupus Erythematosus: Systemic, Lupus Nephritis
[+]

Ganoderma lucidum and San-Miao-San supplements could be used in the treatment of systemic lupus erythematosus.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2016 ;11:23. Epub 2016 Apr 29. PMID: 27134645
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
Additional Keywords : Gene Expression Regulation
[+]

Green tea powder inhibits the progression of lupus-like syndrome and prolongs survival in mice. Nov 01, 2003

Pubmed Data : In Vivo. 2003 Nov-Dec;17(6):545-52. PMID: 14758719
Article Published Date : Nov 01, 2003
Study Type : Animal Study
Additional Links
Substances : Green Tea
Diseases : Lupus Erythematosus: Systemic, Lupus Nephritis
[+]

Immunization with hepatitis B vaccine accelerates SLE-like disease in a murine model.Oct 31, 2014

Pubmed Data : J Autoimmun. 2014 Nov ;54:21-32. Epub 2014 Jul 16. PMID: 25042822
Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Anxiety Disorders, Systemic Lupus Erythematosus, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Aluminum Hydroxide
[+]

Immunoregulatory effects of indole-3-carbinol on monocyte-derived macrophages in systemic lupus erythematosus.Jul 31, 2018

Pubmed Data : Autoimmunity. 2018 Aug ;51(5):199-209. Epub 2018 Oct 5. PMID: 30289282
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Autoimmune Diseases, Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory
[+]

Isogarcinol may be a potential therapeutic drug candidate for future treatment of systemic lupus erythematosus.Sep 29, 2015

Pubmed Data : J Agric Food Chem. 2015 Sep 30 ;63(38):8452-9. Epub 2015 Sep 22. PMID: 26330173
Article Published Date : Sep 29, 2015
Study Type : Animal Study
Additional Links
Substances : Mangosteen
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Lactobacillus fermentum CECT5716: a novel alternative for the prevention of vascular disorders in a mouse model of systemic lupus erythematosus.Jun 06, 2019

Pubmed Data : FASEB J. 2019 Jun 7:fj201900545RR. Epub 2019 Jun 7. PMID: 31173526
Article Published Date : Jun 06, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Gastrointestinal Agents
[+]

Lactobacillus paracasei GMNL-32 exerts a therapeutic effect on cardiac abnormalities in mice.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(9):e0185098. Epub 2017 Sep 21. PMID: 28934296
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lactobacillus paracasei
Diseases : Cardiovascular Disease, Lupus Erythematosus: Systemic
Pharmacological Actions : Anti-Apoptotic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]

Nigella sativa L. as immunomodulator and preventive effect on renal tissue damage of lupus mice induced by pristane.Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2022 Apr ;8(4):e09242. Epub 2022 Apr 6. PMID: 35450390
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory, Renoprotective
[+]

Paeoniflorin attenuates depressive behaviors in systemic lupus erythematosus.Jun 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Jul ;103:248-252. Epub 2018 Apr 24. PMID: 29655166
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Depression, Systemic Lupus Erythematosus
Pharmacological Actions : Antidepressive Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin may be beneficial for the prevention of lung injury in systemic lupus erythematosus.Apr 30, 2018

Pubmed Data : Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 May ;49(3):394-398. PMID: 30014641
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Lung Injury: Acute, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Paeoniflorin may have the potential to be used as a therapeutic agent to reduce the inflammatory activity of systemic lupus erythematosus.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:5161890. Epub 2022 Nov 23. PMID: 36467552
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Renoprotective
[+]

Panax notoginseng saponins reverse P-gp-mediated steroid resistance in lupus.Jan 11, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2022 Jan 12 ;22(1):13. Epub 2022 Jan 12. PMID: 35022006
Article Published Date : Jan 11, 2022
Study Type : Animal Study
Additional Links
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory
[+]

Probiotics prevent hypertension in a murine model of systemic lupus erythematosus.Jul 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Jul 31 ;13(8). Epub 2021 Jul 31. PMID: 34444829
Article Published Date : Jul 30, 2021
Study Type : Animal Study
Additional Links
Substances : Probiotics
Diseases : Hypertension, Oxidative Stress, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Sophorae radix reduces the severity of autoimmune response in a systemic lupus erythematosus mouse model. Jan 01, 2007

Pubmed Data : Lupus. 2007;16(5):335-41. PMID: 17576735
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Sophora Flavescens
Diseases : Lupus Erythematosus: Systemic
[+]

Soy isoflavones supplementation alleviates disease severity in autoimmune-prone mice with lupus. Sep 01, 2008

Pubmed Data : Lupus. 2008 Sep;17(9):814-21. PMID: 18755863
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Genistein, Isoflavones
Diseases : Autoimmune Diseases, Lupus Erythematosus: Systemic
[+]

Sulforaphane ameliorates the severity of psoriasis and systemic lupus erythematosus.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:805508. Epub 2022 Jan 21. PMID: 35126161
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Psoriasis, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory
[+]

The injection of n-hexadecane, pristane, incomplete Freund's adjuvant (IFA), or the adjuvant oil squalene results in lupus-related specific autoantibodies in an animal model. Feb 01, 2006

Pubmed Data : Toxicology. 2006 Feb 1;218(2-3):186-96. Epub 2005 Nov 23. PMID: 16309812
Article Published Date : Feb 01, 2006
Study Type : Animal Study
Additional Links
Diseases : Systemic Lupus Erythematosus
Problem Substances : Freund adjuvant, Hexadecane, Pristane, Squalene, Adjuvant
[+]

The phytoestrogen coumestrol decreases autoantibodies in a mouse model of systemic lupus. Dec 01, 2004

Pubmed Data : J Autoimmun. 2004 Dec;23(4):323-32 PMID: 15571926
Article Published Date : Dec 01, 2004
Study Type : Animal Study
Additional Links
Substances : Coumestrol, phytoestrogens
Diseases : Lupus Erythematosus: Systemic
[+]

These studies show that ultrasoluble curcumin and turmeric could prove useful as a therapeutic intervention in systemic lupus erythematosus and Sjogren's syndrome.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lupus Sci Med. 2015 ;2(1):e000114. Epub 2015 Sep 8. PMID: 26380101
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin, Turmeric
Diseases : Lupus Erythematosus: Systemic, Lymphadenopathy, Oxidative Stress, Proteinuria, Sjogren's Syndrome
Pharmacological Actions : Antioxidants, Renoprotective
Additional Keywords : Plant Extracts
[+]

Vaccine adjuvants can contribute to the pathogenesis of autoimmune diseases such as lupus. Aug 01, 2003

Pubmed Data : J Autoimmun. 2003 Aug;21(1):1-9. PMID: 12892730
Article Published Date : Aug 01, 2003
Study Type : Animal Study
Additional Links
Diseases : Autoimmune Diseases, Lupus Erythematosus: Systemic, Vaccine-induced Toxicity
Problem Substances : Adjuvant, Freund adjuvant, Mineral Oil, Pristane, Squalene
Adverse Pharmacological Actions : Immunotoxic
[+]

Vitamin D3 supplementation diminished the inflammatory conditions in systemic lupus erythematosus.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2016 Apr ;19(4):374-80. PMID: 27279980
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation
[+]

Wormwood suppresses the cellular and humoral response of mice in an experimental model of systemic lupus erythematosus. May 05, 2009

Pubmed Data : Immunopharmacol Immunotoxicol. 2009 May 5. PMID: 19555193
Article Published Date : May 05, 2009
Study Type : Animal Study
Additional Links
Substances : Wormwood
Diseases : Lupus Erythematosus: Systemic
[+]

Combinatorial therapeutic effect of resveratrol and piperine on murine model of systemic lupus erythematosus.Mar 31, 2020

Pubmed Data : Inflammopharmacology. 2020 Apr ;28(2):401-424. Epub 2019 Nov 15. PMID: 31732838
Article Published Date : Mar 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Piperine, Resveratrol
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A review of the role of gut microbiota in lupus systemic lupus erythematosus.Jan 09, 2018

Pubmed Data : Expert Rev Clin Immunol. 2018 10 ;14(10):787-792. Epub 2018 Sep 8. PMID: 30173572
Article Published Date : Jan 09, 2018
Study Type : Review
Additional Links
Diseases : Dysbiosis, Systemic Lupus Erythematosus
Therapeutic Actions : Microbiota Transfer Therapy
Pharmacological Actions : Gastrointestinal Agents
[+]

Curcumin can modulate Th17/Treg balance specifically on CD4+ T cells of SLE patients without affecting healthy subjects.Dec 31, 2015

Pubmed Data : Cent Eur J Immunol. 2016 ;40(4):461-9. Epub 2016 Jan 15. PMID: 26862311
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory: Th17 downregulation
[+]

Curcumin is a natural modulator of immune cells in systemic lupus erythematosus.Jan 31, 2018

Pubmed Data : Autoimmun Rev. 2018 Feb ;17(2):125-135. Epub 2017 Nov 24. PMID: 29180127
Article Published Date : Jan 31, 2018
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Emerging role of air pollution in autoimmune diseases.May 31, 2019

Pubmed Data : Autoimmun Rev. 2019 Jun ;18(6):607-614. Epub 2019 Apr 5. PMID: 30959217
Article Published Date : May 31, 2019
Study Type : Review
Additional Links
Diseases : Air Pollution Linked Toxicity, Autoimmune Diseases, Multiple Sclerosis, Rheumatoid Arthritis, Systemic Lupus Erythematosus
Additional Keywords : Risk Factors
[+]

Exploring the evidence for an immunomodulatory role of vitamin D in juvenile and adult rheumatic disease.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2020 ;11:616483. Epub 2021 Feb 18. PMID: 33679704
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Arthritis, Rheumatoid Arthritis, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

Extracts of Perna analiculus (green-lipped mussel) may reduce inflammation and immunoglobulins in autoimmune diseases like lupus and rheumatoid arthritis. Aug 01, 2008

Pubmed Data : Clin Exp Allergy. 2008 Aug;38(8):1282-9. Epub 2008 May 28. PMID: 16412227
Article Published Date : Aug 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Mussel: Green-lipped (Perna canaliculus)
Diseases : Arthritis: Rheumatoid, Lupus Erythematosus: Systemic
[+]

Heat-solubilized curry spice curcumin inhibits antibody-antigen interaction in in vitro studies indicating it may help to alleviate autoimmune diseases.Aug 01, 2010

Pubmed Data : Mol Nutr Food Res. 2010 Aug;54(8):1202-9. PMID: 20146265
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Autoimmune Diseases, Lupus Erythematosus: Systemic, Sjogren's Syndrome
Additional Keywords : Plant Extracts
[+]

Melatonin exerts beneficial effects in various inflammatory diseases, such as Type 1 diabetes, systemic lupus erythematosus and multiple sclerosis.Feb 01, 2017

Pubmed Data : J Pineal Res. 2017 Feb 2. Epub 2017 Feb 2. PMID: 28152213
Article Published Date : Feb 01, 2017
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Diabetes Mellitus: Type 1, Multiple Sclerosis, Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory
[+]

Melatonin prevents endothelial dysfunction in SLE by activating the nuclear receptor retinoic acid-related orphan receptor-α.Mar 11, 2020

Pubmed Data : Int Immunopharmacol. 2020 Mar 12 ;83:106365. Epub 2020 Mar 12. PMID: 32172204
Article Published Date : Mar 11, 2020
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Cardiovascular Diseases, Endothelial Dysfunction, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Modulation by melatonin of the pathogenesis of inflammatory autoimmune diseases.May 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2013 May 31 ;14(6):11742-66. Epub 2013 May 31. PMID: 23727938
Article Published Date : May 30, 2013
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Autoimmune Diseases, Diabetes Mellitus: Type 1, Inflammation, Inflammatory Bowel Diseases, Multiple Sclerosis, Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory
[+]

Molecular mechanism of celastrol in the treatment of systemic lupus erythematosus based on network pharmacology and molecular docking technology.Nov 13, 2019

Pubmed Data : Life Sci. 2019 Nov 14:117063. Epub 2019 Nov 14. PMID: 31734262
Article Published Date : Nov 13, 2019
Study Type : In Vitro Study
Additional Links
Substances : Celastrol
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin may be a potential therapy for systemic lupus erythematosus.Oct 31, 2018

Pubmed Data : Microb Pathog. 2018 Nov ;124:223-229. Epub 2018 Aug 24. PMID: 30149133
Article Published Date : Oct 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin reduces the inflammatory response of THP-1 cells.Mar 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genes Genomics. 2021 Mar 29. Epub 2021 Mar 29. PMID: 33779948
Article Published Date : Mar 28, 2021
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Inflammation, Lupus Erythematosus: Systemic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The effect of Omega-3 fatty acid supplementation in systemic lupus erythematosus patients.Jan 12, 2022

Pubmed Data : Lupus. 2022 Jan 13:9612033211067985. Epub 2022 Jan 13. PMID: 35023407
Article Published Date : Jan 12, 2022
Study Type : Review
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory
[+]

The effects of vitamin D in autoinflammatory diseases.Dec 31, 2016

Pubmed Data : Clin Calcium. 2017;27(11):1551-1559. PMID: 29074827
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Inflammation, Multiple Sclerosis, Rheumatoid Arthritis, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

The present review focuses on the role of resveratrol in the modulation of cancer as well as of several organ-specific or systemic autoimmune diseases.Jan 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Jan 22 ;9(2). Epub 2020 Jan 22. PMID: 31978952
Article Published Date : Jan 21, 2020
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Autoimmune Diseases, Cancers: All, Diabetes Mellitus: Type 1, Inflammatory Bowel Diseases, Multiple Sclerosis, Rheumatoid Arthritis, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Apoptotic, Chemopreventive, Immunomodulatory
[+]

Therapeutic potential of ω-3 polyunsaturated fatty acids in human autoimmune diseases.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2019 ;10:2241. Epub 2019 Sep 27. PMID: 31611873
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Omega-3 Fatty Acids, Polyunsaturated Fatty Acids (PUFAs)
Diseases : Autoimmune Diseases, Diabetes Mellitus: Type 1, Multiple Sclerosis, Rheumatoid Arthritis, Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

This review provides a general overview of studies describing gut microbiota perturbations in animal models of autoimmune diseases.May 28, 2017

Pubmed Data : Immunology. 2017 May 29. Epub 2017 May 29. PMID: 28556916
Article Published Date : May 28, 2017
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Autoimmune Diseases, Depression: Multiple Sclerosis, Diabetes Mellitus: Type 1, Dysbiosis, Rheumatoid Arthritis, Systemic Lupus Erythematosus
[+]

This review suggests a number of probiotic bacteria that are able to ameliorate immune responses.Dec 19, 2016

Pubmed Data : J Cell Physiol. 2016 Dec 20. Epub 2016 Dec 20. PMID: 27996081
Article Published Date : Dec 19, 2016
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory
Additional Keywords : Microbiota
[+]

This reviewed the current evidences regarding vitamin D role in the pathogenesis and management of different autoimmune diseases.Mar 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Mar 17 ;12(3). Epub 2020 Mar 17. PMID: 32192175
Article Published Date : Mar 16, 2020
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Autoimmune Diseases, Hashimoto's thyroiditis, Rheumatoid Arthritis, Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory
[+]

Ultraviolet-A1 irradiation therapy for systemic lupus erythematosus.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lupus. 2017 Oct ;26(12):1239-1251. Epub 2017 May 8. PMID: 28480786
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Systemic Lupus Erythematosus
Therapeutic Actions : Light Therapy, Sunlight exposure
[+]

Vaccination may contribute to causing a wide variety of autoimmune disorders. Feb 01, 2010

Pubmed Data : Discov Med. 2010 Feb;9(45):90-7. PMID: 20193633
Article Published Date : Feb 01, 2010
Study Type : Commentary
Additional Links
Diseases : Autoimmune Diseases, Guillain-Barre Syndrome, Human Papillomavirus (HPV), Inflammatory Myopathy, Macrophagic myofasciitis , Multiple Sclerosis, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Vaccine-induced Toxicity , Vasculitis
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Haemophilus Influenzae, Vaccination: Hepatitis B, Vaccination: HPV (Gardasil), Vaccination: Influenza, Vaccination: Lyme disease, Vaccination: Mumps-Measles-Rubella (MMR), Vaccination: Rabies, Vaccination: Rotavirus, Vaccination: Tetanus, Vaccination: Varicella (Chicken pox)
[+]

Vitamin D exerts important regulatory functions on cells from the innate as well as from the adaptive immune responseDec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2015 ;6:513. Epub 2015 Oct 12. PMID: 26528285
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Systemic Lupus Erythematosus, Vitamin D Deficiency
Pharmacological Actions : Immunomodulatory
[+]

Vitamin E many inhibit initiation of the autoimmune diseases such as scleroderma, discoid lupus erythematosus, porphyria cutanea tarda, several types of vasculitis, and polymyositis.Mar 01, 1978

Pubmed Data : Cutis. 1978 Mar;21(3):321-5. PMID: 343998
Article Published Date : Mar 01, 1978
Study Type : Commentary
Additional Links
Substances : Vitamin E
Diseases : Autoimmune Diseases, Polymyositis, Porphyrias, Scleroderma, Systemic Lupus Erythematosus, Vasculitis
[+]

Cordyceps improves systemic lupus erythematosus.Sep 01, 2001

Pubmed Data : Zhong Yao Cai. 2001 Sep;24(9):658-9. PMID: 11799778
Article Published Date : Sep 01, 2001
Additional Links
Diseases : Lupus Erythematosus: Systemic
[+]

Royal jelly inhibits autoimmunity in systemic lupus erythematosus prone rats.Nov 01, 2009

Pubmed Data : Br J Sports Med. 2009 Nov;43(11):840-4. Epub 2008 Apr 2. PMID: 19074168
Article Published Date : Nov 01, 2009
Additional Links
Diseases : Lupus Erythematosus: Systemic

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