Lupus Nephritis

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32 Substances Researched for Lupus Nephritis
NameACCKFocus
Tripterygium wilfordii333Locked
Flaxseed212Locked
Cordyceps sinensis110Locked
EPA (Eicosapentaenoic Acid)110Locked
Emodin110Locked
Turmeric110Locked
Ginsenosides13Locked
Honokiol13Locked
Luteolin13Locked
Peony23Locked
Antrodia camphorata12Locked
Astragalus12Locked
Citral12Locked
Cordyceps Militaris12Locked
Enterodiol12Locked
Enterolactone12Locked
Fish Oil12Locked
Green Tea12Locked
Lactobacillus plantarum12Locked
Lignans12Locked
Magnolol12Locked
Piperine12Locked
Procyanidin B2 12Locked
Secoisolariciresinol diglucoside (SDG)12Locked
Soy12Locked
Celastrol11Locked
Fisetin11Locked
Icariin11Locked
Paeonol11Locked
Probiotics11Locked
Punicalagin11Locked
Quercetin11Locked
1 Problematic Actions Researched for Lupus Nephritis
NameACCKFocus
Vaccination: COVID-1912Locked

View the Evidence:
33 Abstracts with Lupus Nephritis Research

[+]

Effectiveness and safety of tripterygium glycosides tablet for lupus nephritis.Sep 30, 2022

Pubmed Data : J Tradit Chin Med. 2022 Oct ;42(5):671-680. PMID: 36083472
Article Published Date : Sep 30, 2022
Study Type : Meta Analysis, Review
Additional Links
Substances : Tripterygium wilfordii
Diseases : Lupus Nephritis
Additional Keywords : Significant Treatment Outcome
[+]

Cordyceps and artemisinin prevent the recurrence of lupus nephritis.Mar 01, 2002

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Mar;22(3):169-71. PMID: 12585097
Article Published Date : Mar 01, 2002
Study Type : Human Study
Additional Links
Substances : Cordyceps sinensis
Diseases : Lupus Nephritis
[+]

Eicosapentaenoic acid (EPA) may exert beneficial effects on lupus nephritis by decreasing oxidative stress. Aug 01, 2006

Pubmed Data : Int J Obes (Lond). 2006 Aug;30(8):1298-307. Epub 2006 Feb 14. PMID: 16097442
Article Published Date : Aug 01, 2006
Study Type : Human Study
Additional Links
Substances : EPA (Eicosapentaenoic Acid)
Diseases : Lupus Nephritis
[+]

Emodin may improve interstitial fibrosis, thus improving prognosis of lupus nephritis. Mar 01, 2000

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Mar;20(3):196-8. PMID: 11789284
Article Published Date : Mar 01, 2000
Study Type : Human Study
Additional Links
Substances : Emodin
Diseases : Lupus Nephritis
[+]

Flaxseed supplementation appears to be renoprotective in lupus nephritis. Apr 01, 2001

Pubmed Data : J Am Coll Nutr. 2001 Apr;20(2 Suppl):143-8. PMID: 11349937
Article Published Date : Apr 01, 2001
Study Type : Human Study
Additional Links
Substances : Flaxseed
Diseases : Lupus Nephritis
[+]

Tripterygium has treatment value in patiens with lupus nephritis. May 01, 2008

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2008 May;33(9):1075-7. PMID: 18652362
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Substances : Tripterygium wilfordii
Diseases : Lupus Nephritis
[+]

Turmeric can decrease proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis.Dec 31, 2011

Pubmed Data : J Ren Nutr. 2012 Jan ;22(1):50-7. Epub 2011 Jul 13. PMID: 21742514
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Lupus Nephritis
Pharmacological Actions : Antihypertensive Agents
Additional Keywords : Phytotherapy
[+]

Honokiol suppresses the aberrant interactions between renal resident macrophages and tubular epithelial cells in lupus nephritis.Feb 28, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Dis. 2023 Mar 1 ;14(3):174. Epub 2023 Mar 1. PMID: 36859530
Article Published Date : Feb 28, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Luteolin attenuates lupus nephritis by regulating macrophage oxidative stress via HIF-1α pathway.Aug 14, 2023

Pubmed Data : Eur J Pharmacol. 2023 Aug 15 ;953:175823. Epub 2023 May 30. PMID: 37263402
Article Published Date : Aug 14, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Luteolin
Diseases : Lupus Nephritis, Oxidative Stress
Pharmacological Actions : Antioxidants, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
[+]

Protopanaxadiol improves lupus nephritis.May 31, 2024

Pubmed Data : J Nat Med. 2024 Jun ;78(3):474-487. Epub 2024 Mar 3. PMID: 38431911
Article Published Date : May 31, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Lupus Nephritis
Pharmacological Actions : Antiproliferative
[+]

A soy diet accelerates renal damage in mice with lupus. Apr 01, 2010

Pubmed Data : J Biol Rhythms. 2010 Apr;25(2):113-22. PMID: 16039550
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Soy
Diseases : Lupus Erythematosus: Systemic, Lupus Nephritis
[+]

Antrodia camphorata attenuates the progression of nephritis in systemic lupus erythematosus-prone mice. Sep 02, 2008

Pubmed Data : Evid Based Complement Alternat Med. 2008 Sep 2. PMID: 18955361
Article Published Date : Sep 02, 2008
Study Type : Animal Study
Additional Links
Substances : Antrodia camphorata
Diseases : Lupus Erythematosus: Systemic, Lupus Nephritis
[+]

Astragalus amplifies the therapeutic effects of cyclophosphamide in the treatmeant of Lupus Nephritis.May 01, 2007

Pubmed Data : Zhong Xi Yi Jie He Xue Bao. 2007 May;5(3):272-5. PMID: 17498486
Article Published Date : May 01, 2007
Study Type : Animal Study
Additional Links
Substances : Astragalus
Diseases : Lupus Nephritis
Additional Keywords : Chemotherapeutic Agent: Cyclophosphamide, Drug-Plant-Vitamin Synergies
[+]

Citral alleviates the mouse ASLN model by inhibition of the activation signal of NLRP3 inflammasome and enhanced activation of Nrf2 antioxidant signaling.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arthritis Res Ther. 2015 ;17:331. Epub 2015 Nov 19. PMID: 26584539
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Citral
Diseases : Lupus Nephritis
Pharmacological Actions : Antioxidants, Nrf2 activation, Renoprotective
[+]

Cordyceps protein alleviates renal injury by inhibiting T cell infiltration and Th1 cell differentiation in lupus nephritis mice.Sep 09, 2024

Pubmed Data : Int Immunopharmacol. 2024 Sep 10 ;138:112566. Epub 2024 Jun 28. PMID: 38943968
Article Published Date : Sep 09, 2024
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Kidney Damage, Lupus Nephritis
Pharmacological Actions : Immunomodulatory
[+]

Effects of Lactobacillus plantarum HFY15 on Lupus nephritis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2022 ;16:2851-2860. Epub 2022 Aug 26. PMID: 36051155
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Interleukin-6 Downregulation
[+]

Fish oil supplementation and energy restriction protect against renal deterioration and oxidative damage in lupus-prone mice. Sep 01, 2005

Pubmed Data : Biochem Pharmacol. 2005 Sep 1;70(5):700-13. PMID: 16022752
Article Published Date : Sep 01, 2005
Study Type : Animal Study
Additional Links
Substances : Fish Oil
Diseases : Lupus Erythematosus: Systemic, Lupus Nephritis
[+]

Green tea powder inhibits the progression of lupus-like syndrome and prolongs survival in mice. Nov 01, 2003

Pubmed Data : In Vivo. 2003 Nov-Dec;17(6):545-52. PMID: 14758719
Article Published Date : Nov 01, 2003
Study Type : Animal Study
Additional Links
Substances : Green Tea
Diseases : Lupus Erythematosus: Systemic, Lupus Nephritis
[+]

Magnolol has a beneficial effect on lupus nephritis.Aug 02, 2017

Pubmed Data : Mol Med Rep. 2017 Aug 3. Epub 2017 Aug 3. PMID: 28791390
Article Published Date : Aug 02, 2017
Study Type : Animal Study
Additional Links
Substances : Magnolol
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Piperine ameliorated lupus nephritis by targeting AMPK-mediated activation of NLRP3 inflammasome.Nov 30, 2018

Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:448-457. Epub 2018 Oct 30. PMID: 30388519
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Piperine
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Procyanidin B2 prevents lupus nephritis development in mice by inhibiting NLRP3 inflammasome activation.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Innate Immun. 2018 Jul ;24(5):307-315. Epub 2018 Jun 6. PMID: 29874961
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Procyanidin B2
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Radix Paeoniae rubra ameliorates lupus nephritis.May 16, 2020

Pubmed Data : Comb Chem High Throughput Screen. 2020 May 17. Epub 2020 May 17. PMID: 32416674
Article Published Date : May 16, 2020
Study Type : Animal Study
Additional Links
Substances : Peony
Diseases : Lupus Nephritis
Pharmacological Actions : Immunomodulatory
[+]

SARS-CoV-2 spike aggravates lupus nephritis and lung fibrosis in systemic lupus erythematosus.Sep 29, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lupus Sci Med. 2024 Sep 30 ;11(2). Epub 2024 Sep 30. PMID: 39349051
Article Published Date : Sep 29, 2024
Study Type : Animal Study
Additional Links
Diseases : Coronavirus Disease (Covid-19), Fibrosis, Lupus Nephritis, Systemic Lupus Erythematosus
Additional Keywords : Increased Risk, SARS-CoV-2 Spike Protein
Anti Therapeutic Actions : Vaccination: COVID-19
[+]

The lignan precursor from flaxseed known as secoisolariresinol diglucoside (SDG) may inhibit the progression of lupus nephritis. Jan 01, 2000

Pubmed Data : Lupus. 2000;9(6):429-36. PMID: 10981647
Article Published Date : Jan 01, 2000
Study Type : Animal Study
Additional Links
Substances : Enterodiol, Enterolactone, Flaxseed, Lignans, Secoisolariciresinol diglucoside (SDG)
Diseases : Lupus Nephritis
[+]

The principal active components of the Chinese herbal remedy Tripterygium wilfordii significantly ameliorated lupus nephritis in mice. Jun 01, 2008

Pubmed Data : Arthritis Rheum. 2008 Jun;58(6):1774-83. PMID: 18512813
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Tripterygium wilfordii
Diseases : Lupus Nephritis
[+]

Anti-inflammatory and immunoregulatory effects of icariin and icaritin.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Jul ;151:113180. Epub 2022 May 27. PMID: 35676785
Article Published Date : Jun 30, 2022
Study Type : Review
Additional Links
Substances : Icariin
Diseases : Asthma, Atherosclerosis, Inflammatory Bowel Diseases, Lupus Nephritis, Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

Celastrol alleviates murine lupus nephritis via inducting CD4+Foxp3+ regulatory T cells.Jul 05, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Folia Histochem Cytobiol. 2022 Jul 6. Epub 2022 Jul 6. PMID: 35792673
Article Published Date : Jul 05, 2022
Study Type : In Vitro Study
Additional Links
Substances : Celastrol
Diseases : Lupus Nephritis
Pharmacological Actions : Immunomodulatory
[+]

Fisetin reduces the senescent tubular epithelial cell burden and also inhibits proliferative fibroblasts in murine lupus nephritis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2022 ;13:960601. Epub 2022 Nov 17. PMID: 36466895
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Fisetin
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Renoprotective
[+]

Paeonol interferes with lupus nephritis by regulating M1/M2 polarization of macrophages.Apr 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Immunol. 2024 May ;169:66-77. Epub 2024 Mar 18. PMID: 38503139
Article Published Date : Apr 30, 2024
Study Type : In Vitro Study
Additional Links
Substances : Paeonol
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Renoprotective
[+]

Punicalagin ameliorates lupus nephritis via inhibition of PAR2.Jul 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Jul 14 ;21(14). Epub 2020 Jul 14. PMID: 32674502
Article Published Date : Jul 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : Punicalagin
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Quercetin is a potential therapeutic drug for lupus nephritis.Aug 31, 2019

Pubmed Data : Phytother Res. 2019 Sep ;33(9):2401-2408. Epub 2019 Jul 18. PMID: 31317585
Article Published Date : Aug 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

The consequences of altered microbiota in immune-related chronic kidney disease. May 20, 2020

Pubmed Data : Nephrol Dial Transplant. 2020 May 21. Epub 2020 May 21. PMID: 32437554
Article Published Date : May 20, 2020
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Diabetic Nephropathy, Dysbiosis, Kidney Diseases, Lupus Nephritis
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory
[+]

Total glucosides of paeony ameliorate pristane-induced Lupus nephritis.Dec 31, 2020

Pubmed Data : Front Immunol. 2021 ;12:683249. Epub 2021 Jul 5. PMID: 34290705
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Peony
Diseases : Lupus Nephritis
Pharmacological Actions : Interleukin-4 upregulation

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