Lymphedema

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7 Substances Researched for Lymphedema
NameACCKFocus
Wobenzym110Locked
Yellow Sweet Clover (Melilotus officinalis)110Locked
Andrographolide13Locked
Diosmin 12Locked
Hesperidin12Locked
Horse Chestnut12Locked
Hydroxytyrosol11Locked
5 Therapeutic Actions Researched for Lymphedema
NameACCKFocus
Photobiomodulation23193Locked
Acupuncture230Locked
Thermal Therapy: Far-Infrared330Locked
Moxibustion120Locked
Laser Treatment 110Locked

View the Evidence:
35 Abstracts with Lymphedema Research

[+]

Effect of low-level laser therapy on pain and swelling in women with breast cancer-related lymphedema.May 31, 2015

Pubmed Data : J Cancer Surviv. 2015 Jun ;9(2):287-304. Epub 2014 Nov 29. PMID: 25432632
Article Published Date : May 31, 2015
Study Type : Meta Analysis, Review
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Analgesics
[+]

Comparison efficacy and safety of acupuncture and moxibustion therapies in breast cancer-related lymphedema.Dec 31, 2023

Pubmed Data : PLoS One. 2024 ;19(5):e0303513. Epub 2024 May 14. PMID: 38743748
Article Published Date : Dec 31, 2023
Study Type : Meta Analysis
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Acupuncture, Moxibustion
Pharmacological Actions : Chemotherapeutic
[+]

Effect of various photobiomodulation regimens on breast cancer-related lymphedema.Dec 21, 2023

Pubmed Data : Lasers Med Sci. 2023 Dec 22 ;39(1):11. Epub 2023 Dec 22. PMID: 38129368
Article Published Date : Dec 21, 2023
Study Type : Meta Analysis
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

A pilot randomized trial evaluating low-level laser therapy as an alternative treatment to manual lymphatic drainage for breast cancer-related lymphedema.Jun 30, 2013

Pubmed Data : Oncol Nurs Forum. 2013 Jul ;40(4):383-93. PMID: 23803270
Article Published Date : Jun 30, 2013
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Acupuncture may stabilise symptoms of lymphoedema in breast cancer patients and no major safety concerns were identified.Sep 30, 2014

Pubmed Data : Acupunct Med. 2014 Oct ;32(5):387-93. Epub 2014 Jul 2. PMID: 24990160
Article Published Date : Sep 30, 2014
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Acupuncture
Additional Keywords : Significant Treatment Outcome
[+]

Changes in tissue water and indentation resistance of lymphedematous limbs accompanying low level laser therapy (LLLT) of fibrotic skin.Nov 30, 2011

Pubmed Data : Lymphology. 2011 Dec ;44(4):168-77. PMID: 22458118
Article Published Date : Nov 30, 2011
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Complementary low-level laser therapy for breast cancer-related lymphedema.Jan 31, 2020

Pubmed Data : Lasers Med Sci. 2020 Feb ;35(1):95-105. Epub 2019 May 11. PMID: 31079232
Article Published Date : Jan 31, 2020
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemopreventive
[+]

Efficacy of pneumatic compression and low-level laser therapy in the treatment of postmastectomy lymphoedema.Jan 31, 2009

Pubmed Data : Clin Rehabil. 2009 Feb ;23(2):117-24. PMID: 19164399
Article Published Date : Jan 31, 2009
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Far infrared radiation therapy provides an effective treatment modality for patients with chronic lymphedema.May 31, 2017

Pubmed Data : Arch Gynecol Obstet. 2017 Jun ;295(6):1441-1450. Epub 2017 Apr 22. PMID: 28434105
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Thermal Therapy: Far-Infrared
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-18 down-regulation, Interleukin-2 Downregulation
[+]

Far infrared ray treatment should be considered as feasible and safe for the treatment of breast cancer related lymphedema patients.Jun 30, 2017

Pubmed Data : J Photochem Photobiol B. 2017 Jul ;172:95-101. Epub 2017 May 11. PMID: 28535427
Article Published Date : Jun 30, 2017
Study Type : Human In Vitro, Human Study
Additional Links
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Lymphedema
Therapeutic Actions : Thermal Therapy: Far-Infrared
[+]

Findings from this study suggested the potential benefits of PBM therapy in treatment of chronic head and neck lymphedema.Aug 31, 2023

Pubmed Data : J Palliat Med. 2023 Sep ;26(9):1225-1233. Epub 2023 Apr 28. PMID: 37116057
Article Published Date : Aug 31, 2023
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Infrared radiation treatment could be considered as an alternative monotherapy and a useful adjunctive to surgical lymphedema procedures.Mar 31, 2017

Pubmed Data : Lasers Med Sci. 2017 Apr ;32(3):485-494. Epub 2017 Jan 26. PMID: 28127644
Article Published Date : Mar 31, 2017
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Thermal Therapy: Far-Infrared
[+]

Investigation of the effect of low-level laser therapy on arm lymphedema in breast cancer patients.Apr 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Health Sci Rep. 2023 May ;6(5):e1261. Epub 2023 May 17. PMID: 37205934
Article Published Date : Apr 30, 2023
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Long-term effectiveness of combined intermittent pneumatic compression plus low-level laser therapy in patients with postmastectomy lymphedema.Mar 31, 2022

Pubmed Data : Lymphat Res Biol. 2022 Apr ;20(2):175-184. Epub 2021 Apr 7. PMID: 33826415
Article Published Date : Mar 31, 2022
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Low-level laser therapy in management of postmastectomy lymphedema.Jun 30, 2006

Pubmed Data : Lasers Med Sci. 2006 Jul ;21(2):90-4. Epub 2006 May 4. PMID: 16673054
Article Published Date : Jun 30, 2006
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Photobiomodulation
[+]

Managing postmastectomy lymphedema with low-level laser therapy.Sep 30, 2009

Pubmed Data : Photomed Laser Surg. 2009 Oct ;27(5):763-9. PMID: 19878027
Article Published Date : Sep 30, 2009
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Photobiomodulation therapy in head and neck cancer-related lymphedema.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2021 ;20:15347354211037938. PMID: 34387119
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Platelet-rich plasma, low-level laser therapy, and complex decongestive physiotherapy in patients with lower limb lymphedema.Sep 30, 2020

Pubmed Data : Lymphat Res Biol. 2020 Oct ;18(5):439-447. Epub 2020 Feb 19. PMID: 32073990
Article Published Date : Sep 30, 2020
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

The short-term effects of low-level laser therapy in the management of breast-cancer-related lymphedema.Apr 30, 2011

Pubmed Data : Support Care Cancer. 2011 May ;19(5):685-90. Epub 2010 May 6. PMID: 20445997
Article Published Date : Apr 30, 2011
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Treatment of chronic postmastectomy lymphedema with low level laser therapy.May 31, 1998

Pubmed Data : Lymphology. 1998 Jun ;31(2):74-86. PMID: 9664272
Article Published Date : May 31, 1998
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Photobiomodulation
[+]

Treatment of post-mastectomy lymphedema with laser therapy.Dec 31, 2010

Pubmed Data : J Surg Res. 2011 Jan ;165(1):82-90. Epub 2010 Apr 18. PMID: 20538293
Article Published Date : Dec 31, 2010
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Laser Treatment
Pharmacological Actions : Chemotherapeutic
[+]

Treatment of postmastectomy lymphedema with low-level laser therapy.Sep 14, 2003

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer. 2003 Sep 15 ;98(6):1114-22. PMID: 12973834
Article Published Date : Sep 14, 2003
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Wobenzym is effective in the treatment of lymphedema after breast operation.Jan 01, 1996

Pubmed Data : Wien Med Wochenschr. 1996;146(4):67-72; discussion 74. PMID: 8650941
Article Published Date : Jan 01, 1996
Study Type : Human Study
Additional Links
Substances : Wobenzym
Diseases : Lymphedema
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Yellow Sweet Clover (Melilotus officinalis) is has modest but statistically significant therapeutic value in Lymphedema. Nov 01, 1999

Pubmed Data : Clin Ter. 1999 Nov-Dec;150(6):403-8. PMID: 10756659
Article Published Date : Nov 01, 1999
Study Type : Human Study
Additional Links
Substances : Yellow Sweet Clover (Melilotus officinalis)
Diseases : Lymphedema
Pharmacological Actions : Anti-edemic
[+]

Andrographolide promotes lymphangiogenesis and lymphatic vessel remodeling to alleviate secondary lymphedema.Sep 02, 2024

Pubmed Data : Biochem Biophys Res Commun. 2024 Sep 3 ;723:150179. Epub 2024 May 25. PMID: 38820623
Article Published Date : Sep 02, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Andrographolide
Diseases : Lymphedema
[+]

Complex decongestive physical therapy and low-level laser therapy for the treatment of pediatric congenital lymphedema.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Phys Ther Sci. 2015 Jun ;27(6):2021-2. Epub 2015 Jun 30. PMID: 26180372
Article Published Date : May 31, 2015
Study Type : Human: Case Report
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Kinesio taping and low-level laser therapy in breast cancer-related lymphedema in an arm with arteriovenous fistula for hemodialysis.May 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk J Phys Med Rehabil. 2020 Jun ;66(2):214-218. Epub 2020 May 18. PMID: 32760900
Article Published Date : May 31, 2020
Study Type : Human: Case Report
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Photobiomodulation
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A combination of diosmin and hesperidin (Daflon) improves lymphatic flow indicating its therapeutic role in conditions like perivascular edema. Sep 01, 1995

Pubmed Data : Int Angiol. 1995 Sep;14(3 Suppl 1):36-8. PMID: 8919263
Article Published Date : Sep 01, 1995
Study Type : Animal Study
Additional Links
Substances : Diosmin , Hesperidin
Diseases : Lymphatic Diseases, Lymphatic Stasis, Lymphedema
Pharmacological Actions : Lymphagogue
[+]

Anti-inflammatory and lymphangiogenetic effects of low-level laser therapy on lymphedema in an experimental mouse tail model.Jan 31, 2016

Pubmed Data : Lasers Med Sci. 2016 Feb ;31(2):289-96. Epub 2015 Dec 29. PMID: 26714983
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The role of escin as a topical agent for lymphedema treatment.Aug 21, 2023

Pubmed Data : Int J Low Extrem Wounds. 2023 Aug 22:15347346231195944. Epub 2023 Aug 22. PMID: 37605640
Article Published Date : Aug 21, 2023
Study Type : Animal Study
Additional Links
Substances : Horse Chestnut
Diseases : Lymphedema
[+]

A systematic review of the effect of low-level laser therapy in the management of breast cancer-related lymphedema.Oct 31, 2012

Pubmed Data : Support Care Cancer. 2012 Nov ;20(11):2977-84. Epub 2012 Aug 9. PMID: 22875413
Article Published Date : Oct 31, 2012
Study Type : Review
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

Molecular pathways involved in lymphedema: Hydroxytyrosol as a candidate natural compound for treating the effects of lymph accumulation.Nov 29, 2019

Pubmed Data : J Biotechnol. 2019 Nov 30 ;308:82-86. Epub 2019 Nov 30. PMID: 31794783
Article Published Date : Nov 29, 2019
Study Type : Review
Additional Links
Substances : Hydroxytyrosol
Diseases : Lymphedema
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Photobiomodulation or low-level laser therapy in the management of cancer therapy-induced mucositis, dermatitis and lymphedema.Jun 30, 2018

Pubmed Data : Curr Opin Oncol. 2018 Jul ;30(4):226-232. PMID: 29794809
Article Published Date : Jun 30, 2018
Study Type : Review
Additional Links
Diseases : Lymphedema, Mucositis
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

The effectiveness and safety of low-level laser therapy on breast cancer-related lymphedema.Mar 31, 2022

Pubmed Data : Lasers Med Sci. 2022 Apr ;37(3):1389-1413. Epub 2021 Nov 15. PMID: 34779937
Article Published Date : Mar 31, 2022
Study Type : Review
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic
[+]

The findings of this comprehensive study demonstrated that LLLT (PBM) was successful in diminishing arm circumference and volume than improving shoulder mobility and pain.Aug 29, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cancer. 2022 Aug 30 ;22(1):937. Epub 2022 Aug 30. PMID: 36042421
Article Published Date : Aug 29, 2022
Study Type : Review
Additional Links
Diseases : Breast Cancer, Lymphedema
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemotherapeutic

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