Melanoma

Name	AC	CK
Coffee	4	60
Curcumin	38	46
Vitamin D	10	37
Vitamin C	17	22
Chlorogenic Acid	1	20
Ginsenosides	12	17
Sulforaphane	6	17
Apigenin	5	12
EGCG (Epigallocatechin gallate)	8	11
Quercetin	8	11
Resveratrol	9	11
Broccoli Sprouts	1	10
Caffeine	1	10
Flavonoids	7	9
Lichens	5	9
Mistletoe	4	9
Indole-3-Carbinol	7	8
Chaga Mushroom (Inonotus obliquus)	4	7
Phellinus Linteus	5	7
Phloretin	3	7
Tocotrienol: Delta	3	7
Berberine	6	6
Cannabinoids	4	6
Fucoidan	6	6
Green Tea	5	6
Parthenolide	5	6
Pterostilbene	4	6
Rosemary	2	6
Zerumbone	2	6
Anthocyanins	4	5
Betulinic acid	4	5
Chrysin	4	5
Fisetin	4	5
Homeopathic Medicine: All	3	5
Isoliquiritigenin	4	5
Licorice	5	5
Luteolin	3	5
Polyphenols	4	5
Thymoquinone	4	5
Ashwagandha	4	4
Emodin	4	4
Moringa oleifera	4	4
Antrodia camphorata	2	3
Bamboo	2	3
Beta-Elemene	3	3
Cannabinoids: Synthetic	2	3
Cannabis	3	3
Cashew	2	3
Catechin	2	3
Cinnamaldehyde	2	3
Cinnamon	2	3
Collagen	2	3
Ellagic Acid	2	3
Essential Oils: Unspecified	2	3
Fermented Foods and Beverages	2	3
Gallic Acid	2	3
Genistein	3	3
Ginkgo biloba	2	3
Grape	2	3
Nexrutine (Phellodendrom)	2	3
Oleuropein	2	3
Olive leaf extract	2	3
Raspberry	2	3
Reishi Mushroom	2	3
Tanshinone IIA	2	3
Turkey Tail Mushroom	2	3
Vitamin A	2	3
Whey	2	3
Xanthohumol	2	3
Acai	1	2
Aloe Vera	2	2
Angelica	1	2
Apple	1	2
Baicalein	2	2
Bee Propolis	2	2
Bee Venom	2	2
Benzyl isothiocyanate	2	2
Broccoli	1	2
Burdock	1	2
Cannabidiol	2	2
Carnosic Acid	2	2
Carnosol	2	2
Carrot	1	2
Celery	1	2
Cordyceps sinensis	1	2
Crocin	1	2
Cruciferous Vegetables	2	2
Cucurbitacin B	1	2
Delphinidin	1	2
Diosmin	1	2
Flaxseed	1	2
Frankincense	1	2
Ginseng	1	2
Hibiscus sabdariffa	2	2
Holy Basil	1	2
Kaempferol	1	2
Lemon Peel	1	2
Magnolol	2	2
Melatonin	2	2
Nicotinamide	1	2
Oleanolic acid	1	2
Olive Oil	2	2
Paeonol	1	2
Papaya: Fermented	1	2
Phenethyl isothiocyanate	2	2
Phyllanthus amarus	2	2
Phyllanthus niruri (Stonebreaker)	2	2
Phyllanthus urinaria	2	2
Piceatannol	2	2
Pomegranate	1	2
Prickly Pear Cactus	1	2
Red Wine	1	2
Red Wine Extract	1	2
Sage	2	2
Sandalwood	2	2
Shikonin	2	2
Soy Protein	1	2
Tea Tree	2	2
Thyme	2	2
Tocotrienol: Alpha	1	2
Triptolide	1	2
Vitamin E: Gamma-tocotrienol	2	2
Wheat Grass	1	2
Adlay	1	1
Allicin	1	1
Asiatic Acid	1	1
Astaxanthin	1	1
Bai Zhu	1	1
Banana Peel	1	1
Bay leaf	1	1
Beta Sitosterol	1	1
Bloodroot	1	1
Blueberry	1	1
Bromelain	1	1
Caffeic Acid	1	1
Caffeic acid phenethyl ester	1	1
Chokeberry	1	1
Citral	1	1
Curcumol	1	1
Daidzein	1	1
Damnacanthal	1	1
Dandelion	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Deuterium (heavy water)	1	1
Diosgenin	1	1
Eucalyptus	1	1
Evening Primrose Oil	1	1
Feverfew	1	1
Folic Acid	1	1
Garlic	1	1
Geum japonicum	1	1
Ginger	1	1
Ginseng (Korean)	1	1
Glycyrrhizin	1	1
Goldenseal	1	1
Gotu Kola	1	1
Grapefruit	1	1
Gymnema Sylvestre	1	1
Hibiscus rosa-sinensis	1	1
Honokiol	1	1
Huaier (Trametes robiniophila murr)	1	1
Hydroxytyrosol	1	1
Inositol Hexaphosphate	1	1
Kiwifruit	1	1
Lactoferrin	1	1
Loquat Leaves	1	1
Lotus	1	1
Lutein	1	1
Lycopene	1	1
Marigold	1	1
Medicinal Mushrooms	1	1
Modified Citrus Pectin	1	1
Naringenin	1	1
Nettle	1	1
Okra	1	1
Oleocanthal	1	1
Omega-3 Fatty Acids	1	1
Oridonin	1	1
P-Coumaric Acid	1	1
Pea	1	1
Pear	1	1
Piperidines	1	1
Polygonatum cyrtonema	1	1
Potato	1	1
Psychedelics:All	1	1
Rice Bran	1	1
S-Adenosylmethionine (SAMe)	1	1
Saffron	1	1
Seaweed: Brown	1	1
Sesame Seed Oil	1	1
Sesamol	1	1
Sophora Flavescens	1	1
Squash: Butternut	1	1
Sugar-apple	1	1
Syrian rue	1	1
Tocotrienol: Gamma	1	1
Tocotrienols	1	1
Ursolic Acid	1	1
Verbascoside	1	1
Viruses: Beneficial	1	1
Vitamin B-3 (Niacin)	1	1
Vitamin E	1	1
Vitamin K	1	1
Walnut	1	1
Wasabi	1	1
Wheat Germ	1	1
White Button Mushroom	1	1
Wormwood	1	1
Zeaxanthin	1	1
beta-Carotene	1	1

Name	AC	CK
Eszopiclone	1	20
Hypnotic Drugs	1	20
Ramelteon	1	20
Zaleplon	1	20
Zolpidem (trade name Ambien)	1	20
Pesticides	2	12
Dl-alpha-tocopherol acetate	1	10
Glyphosate	1	10
Meat	1	10
Mineral Oil	1	10
Statin Drugs	1	10
Acetaminophen	1	2
Cisplatin	1	2
Doxorubicin	1	2
Paclitaxel	1	2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	1

Name	AC	CK
Sunlight exposure	3	12
Dietary Modification: Mediterranean Diet	1	10
Gerson Therapy	1	10
Light-Emitting Diodes (LEDs) Therapy	1	5
Dietary Modification: Low Carbohydrate	1	2
Photodynamic therapy	1	2
Heat Therapy	1	1
Laser Treatment: Low-Level	1	1
Light Therapy	1	1

Name	AC	CK
Electromagnetic Field Harms	1	10
Electromagnetic Radiation	1	10
Biopsy Procedure: Sentinel Lymph-Node	1	1
Biopsy: Various Tissue	1	1

[+]

Hypnotic drugs increase the risk of skin cancer.Sep 01, 2008

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Pubmed Data : J Sleep Res. 2008 Sep;17(3):245-50. PMID: 18844818

Article Published Date : Sep 01, 2008

Study Type : Meta Analysis

Additional Links

Diseases : Melanoma, Skin Cancer

Problem Substances : Eszopiclone, Hypnotic Drugs, Ramelteon, Zaleplon, Zolpidem (trade name Ambien)

Adverse Pharmacological Actions : Carcinogenic

[+]

There is some evidence for the beneficial effects of regular coffee consumption on melanoma.Mar 31, 2016

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Pubmed Data : Am J Clin Dermatol. 2016 Apr ;17(2):113-23. PMID: 26547919

Pubmed Data : Melanoma Res. 2002 Feb;12(1):83-90. PMID: 11828262

Article Published Date : Feb 01, 2002

Study Type : Human Study

Additional Links

Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Melanoma

Problem Substances : Dl-alpha-tocopherol acetate

[+]

Evaluation of biodistribution of sulforaphane after administration of oral broccoli sprout extract in melanoma patients.Apr 23, 2018

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Pubmed Data : Cancer Prev Res (Phila). 2018 Apr 24. Epub 2018 Apr 24. PMID: 29691233

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Lett. 2017 May ;13(5):3787-3792. Epub 2017 Mar 23. PMID: 28521479

Article Published Date : Apr 30, 2017

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Melanoma, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Red and processed meat intake was inversely associated with melanoma risk in these two cohorts.Apr 22, 2018

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Pubmed Data : J Am Acad Dermatol. 2018 Apr 23. Epub 2018 Apr 23. PMID: 29698709

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Pubmed Data : Am J Clin Nutr. 2019 Aug 5. Epub 2019 Aug 5. PMID: 31380561

Article Published Date : Aug 05, 2019

Study Type : Human Study

Additional Links

Diseases : Basal Cell Carcinoma, Melanoma, Skin Cancer

Therapeutic Actions : Dietary Modification: Mediterranean Diet

Pharmacological Actions : Anti-cancer, Anticarcinogenic Agents

[+]

The study suggests an augmented risk of cutaneous melanoma among subjects with exposure to pesticides.Mar 31, 2016

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Pubmed Data : J Occup Environ Med. 2016 Apr ;58(4):370-5. PMID: 27058477

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Pubmed Data : Melanoma Res. 2022 10 1 ;32(5):384-387. Epub 2022 Aug 17. PMID: 35979670

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Melanoma, Skin Cancer, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

An extract of Rosmarinus officinals L. was able to efficiently reduce the proliferation of the human melanoma A375 cells.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(7):e0132439. Epub 2015 Jul 15. PMID: 26176704

Article Published Date : Dec 31, 2014

Study Type : Human In Vitro

Additional Links

Substances : Rosemary

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Dose Response, Plant Extracts

[+]

Antiproliferative and proapoptotic effects of erucin, a diet-derived H2S donor, on human melanoma cells.Dec 25, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Am J Cancer Res. 2021 ;11(9):4199-4219. Epub 2021 Sep 15. PMID: 34659883

Article Published Date : Dec 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Capsaicin

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Autophagy Inhibitors

[+]

Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells.Sep 30, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Homeopathy. 2016 Feb ;105(1):109-18. Epub 2015 Sep 26. PMID: 26828006

Article Published Date : Jan 31, 2016

Study Type : Animal Study

Additional Links

Substances : Homeopathic Medicine: All

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Chemopreventive, Chemotherapeutic

[+]

An isocaloric carbohydrate restriction diet and natural AMPK activating agents induce synergistic anticancer effects.Mar 18, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur J Cancer Prev. 2015 Mar 19. Epub 2015 Mar 19. PMID: 25747515

Article Published Date : Mar 18, 2015

Study Type : In Vitro Study, Transgenic Animal Study

Additional Links

Substances : Catechin , Curcumin, Quercetin, Resveratrol

Diseases : Liver Cancer, Melanoma

Therapeutic Actions : Dietary Modification: Low Carbohydrate

Pharmacological Actions : AMP-activated protein kinase modulation , Antiproliferative , Chemopreventive, Interleukin-6 Downregulation, SIRT1 Activator

Additional Keywords : Diet Induced Tumor Suppression

[+]

Angelica sinensis has therapeutic effect against melanoma cells in the mouse experimental model.Mar 01, 2007

Article Published Date : May 29, 2006

Study Type : Animal Study

Additional Links

Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Melanoma

Pharmacological Actions : Immunostimulatory

[+]

Arctium lappa extract suppresses inflammation and inhibits melanoma progression.Jul 28, 2019

Pubmed Data : Phytomedicine. 2021 Dec 22 ;99:153904. Epub 2021 Dec 22. PMID: 35231825

Article Published Date : Dec 21, 2021

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Cancers: All, Melanoma

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory

Additional Keywords : Tumor Microenvironment

[+]

Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells.Apr 18, 2004

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Cancer. 2004 Apr 19 ;90(8):1672-8. PMID: 15083202

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FASEB J. 2006 Dec ;20(14):2633-5. Epub 2006 Oct 25. PMID: 17065222

Article Published Date : Nov 30, 2006

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Cannabinoids , Cannabinoids: Synthetic

Diseases : Melanoma

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Chemotherapeutic

Additional Keywords : Cannabinoid Receptors, Selective Cytotoxicity

[+]

CARI III exerted anti-cancer activity that is comparable to doxorubicin against melanoma in vivo, as well as in vitro.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2014 ;19(9):14383-95. Epub 2014 Sep 12. PMID: 25221864

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2020 Jan 29 ;12(2). Epub 2020 Jan 29. PMID: 32013122

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Pubmed Data : Sci Rep. 2018 Oct 24 ;8(1):15726. Epub 2018 Oct 24. PMID: 30356079

Article Published Date : Oct 23, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Fisetin

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Antiproliferative

Additional Keywords : Natural Substances Versus Drugs

[+]

Cordyceps has significant therapeutic action against melanoma cell growth in mice with no adverse side effects.Dec 01, 2004

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Pubmed Data : Clin Exp Pharmacol Physiol. 2004 Dec;31 Suppl 2:S51-3 PMID: 15649290

Article Published Date : Dec 01, 2004

Study Type : Animal Study

Additional Links

Substances : Cordyceps sinensis

Diseases : Melanoma

[+]

Coupling to a cancer cell-specific antibody potentiates tumoricidal properties of curcumin.Aug 14, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Cancer. 2012 Aug 15 ;131(4):E569-78. Epub 2012 Jan 3. PMID: 21989768

Article Published Date : Aug 14, 2012

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Melanoma

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Crocin may exhibit significant melanoma tumor remission properties by positively modulating tumor growth related parameters.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Oncol Rep. 2015 Nov 12. Epub 2015 Nov 12. PMID: 26573768

Article Published Date : Nov 11, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Autophagy Up-regulation, Cell cycle arrest

[+]

Curcumin exerts its in vitro anti-angiogenic and in vivo anti-tumour properties through combined PDE2 and PDE4 inhibition.Jan 31, 2015

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Pubmed Data : Thromb Haemost. 2015 Feb ;113(2):319-28. Epub 2014 Sep 18. PMID: 25230992

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Pubmed Data : Oncotarget. 2017 Mar 31. Epub 2017 Mar 31. PMID: 28410190

Article Published Date : Mar 30, 2017

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : High Fat Diet, Melanoma

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor C Inhibitor, Vascular Endothelial Growth Factor D Inhibitor

[+]

Diosmin has a synergistic effect with interferon-alpha in inhibiting metastatic pulmonary melanoma. Jun 01, 2009

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Pubmed Data : Cancer Biother Radiopharm. 2009 Jun;24(3):347-52. PMID: 19538057

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2019 May 28 ;10(37):3472-3490. Epub 2019 May 28. PMID: 31191820

Article Published Date : May 27, 2019

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Pubmed Data : Oncol Res. 2006 ;16(5):211-6. PMID: 17294801

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Pubmed Data : Free Radic Biol Med. 2015 Jun 25. Epub 2015 Jun 25. PMID: 26119785

Article Published Date : Jun 24, 2015

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Melanoma, Melanoma: Metastatic

Pharmacological Actions : Antioxidants, Apoptotic, Chemotherapeutic, Cytotoxic

Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Piper nigrum extract suppresses tumor growth and enhances the antitumor immune response in murine models of breast cancer and melanoma.Sep 30, 2023

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Pubmed Data : Food Funct. 2015 Sep 2 ;6(9):3022-34. PMID: 26200777

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Cancer. 2011 Apr 15 ;128(8):1955-65. PMID: 20568104

Article Published Date : Apr 14, 2011

Pubmed Data : J Photochem Photobiol B. 2017 Jan ;166:301-310. Epub 2016 Dec 9. PMID: 28024281

Article Published Date : Dec 31, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Acai

Diseases : Melanoma

Therapeutic Actions : Photodynamic therapy

Pharmacological Actions : Antiproliferative , Photosensitizing Agents

Additional Keywords : Plant Oils

[+]

Tumor regression after intravenous administration of targeted vesicles entrapping the vitamin E α-tocotrienol.Jan 27, 2017

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Pubmed Data : J Control Release. 2017 Jan 28 ;246:79-87. Epub 2016 Dec 18. PMID: 27993600

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Pubmed Data : PLoS One. 2010 Jun 10 ;5(6):e11051. Epub 2010 Jun 10. PMID: 20548792

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Pubmed Data : Cancers (Basel). 2021 Jan 29 ;13(3). Epub 2021 Jan 29. PMID: 33572775

Article Published Date : Jan 28, 2021

Study Type : Animal Study

Additional Links

Substances : Xanthohumol

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Antiproliferative

[+]

Aloin promotes cell apoptosis by targeting HMGB1-TLR4-ERK axis in human melanoma cells.Dec 31, 2019

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Pubmed Data : Biosci Biotechnol Biochem. 2010;74(4):753-8. PMID: 20445320

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : White Button Mushroom

Diseases : Melanoma, Pigmentation Disorders

[+]

A comprehensive assessment of apigenin as an antiproliferative, proapoptotic, antiangiogenic and immunomodulatory phytocompound.Apr 15, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 Apr 16 ;11(4). Epub 2019 Apr 16. PMID: 30995771

[+]

Aloe-emodin significantly reduced the proliferation, stemness and invasive potential of melanospheres.Jun 02, 2015

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Pubmed Data : Eur J Pharmacol. 2015 Jun 3 ;762:283-292. Epub 2015 Jun 3. PMID: 26048310

Article Published Date : Jun 02, 2015

Study Type : In Vitro Study

Additional Links

Substances : Emodin

Diseases : Melanoma, Melanoma: Metastatic

Pharmacological Actions : Anti-metastatic, Antiproliferative , Chemotherapeutic, Immunomodulatory

Additional Keywords : Natural Substance/Drug Synergy

[+]

Aloin enhances cisplatin antineoplastic activity in B16-F10 melanoma cells by transglutaminase-induced differentiation.Dec 31, 2012

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Pubmed Data : Amino Acids. 2013 Jan ;44(1):293-300. Epub 2011 Dec 3. PMID: 22139409

Ankaferd hemostat made from five plants has growth inhibitory activity against melanoma cells. Dec 31, 2016

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Pubmed Data : SAGE Open Med. 2017 ;5:2050312116689519. Epub 2017 Feb 10. PMID: 28293423

Article Published Date : Dec 31, 2016

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Pubmed Data : J Agric Food Chem. 2012 Aug 15 ;60(32):7866-72. Epub 2012 Aug 6. PMID: 22838509

Article Published Date : Aug 14, 2012

Study Type : In Vitro Study

Additional Links

Substances : Eucalyptus

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Antiproliferative activity of walnut proteins and walnut protein hydrolysates.Sep 24, 2017

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Pubmed Data : J Med Food. 2017 Sep 25. Epub 2017 Sep 25. PMID: 28945497

Article Published Date : Sep 24, 2017

Study Type : In Vitro Study

Additional Links

Substances : Walnut

Diseases : Acute Myeloid Leukemia, Melanoma, Prostate Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Dose Response, Selective Antiproliferation

[+]

Antiproliferative sesquiterpene lactones from the roots of Inula helenium.Sep 30, 2002

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2002 Oct ;25(10):1370-2. PMID: 12392098

Article Published Date : Sep 30, 2002

Study Type : In Vitro Study

Additional Links

Substances : Elecampane

Diseases : Cervical Cancer, Melanoma

Pharmacological Actions : Antiproliferative

Additional Keywords : Plant Extracts

[+]

Antitumorigenic effect of damnacanthal on melanoma cell viability through p53 and NF-κB/caspase-3 signaling pathways.Oct 31, 2018

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Available data so far, justify the use of Fermented wheat germ extract as a non-prescription medical nutriment for cancer patients.Sep 04, 2011

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Pubmed Data : Planta Med. 2022 Jul 19. Epub 2022 Jul 19. PMID: 35853472

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Pubmed Data : Toxicol Appl Pharmacol. 2021 Mar 11 ;418:115484. Epub 2021 Mar 11. PMID: 33716044

Article Published Date : Mar 10, 2021

Study Type : In Vitro Study

Additional Links

Substances : Berberine

Diseases : Melanoma

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

Bergamottin induces DNA damage and inhibits malignant progression in melanoma.Dec 31, 2020

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Pubmed Data : Pharmaceutics. 2020 May 24 ;12(5). Epub 2020 May 24. PMID: 32456290

Article Published Date : May 23, 2020

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Melanoma

Pharmacological Actions : Cytotoxic

[+]

Cancer glycolytic dependence as a new target of olive leaf extract.Jan 28, 2020

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Pubmed Data : Oncol Lett. 2018 Feb ;15(2):2393-2400. Epub 2017 Dec 14. PMID: 29434949

Article Published Date : Jan 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Carnosic Acid

Diseases : Melanoma

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Natural Substance/Drug Synergy

[+]

Carnosic acid impedes cell growth and enhances anti-cancer effects of carmustine and lomustine in melanoma.May 21, 2018

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Pubmed Data : Biosci Rep. 2018 May 22. Epub 2018 May 22. PMID: 29789400

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Pubmed Data : Oncoimmunology. 2022 ;11(1):2019922. Epub 2022 Jan 4. PMID: 35003897

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Diseases : Melanoma

Therapeutic Actions : Thermal Therapy: Far-Infrared

Additional Keywords : Tumor Microenvironment

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Cell cycle regulation by berberine in human melanoma A375 cells.Jul 31, 2020

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Pubmed Data : Bull Exp Biol Med. 2020 Aug ;169(4):491-496. Epub 2020 Sep 11. PMID: 32915362

Article Published Date : Jul 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Berberine

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, MicroRNA modulator

[+]

Chaga Mushroom (Inonotus obliquus) exhibits anticancer potential against melanoma cell lines in vitro and in vivo. Jan 21, 2009

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Pubmed Data : J Ethnopharmacol. 2009 Jan 21;121(2):221-8. Epub 2008 Oct 25. PMID: 19041933

Article Published Date : Jan 21, 2009

Study Type : Review

Additional Links

Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Melanoma

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomedicines. 2022 Jun 21 ;10(7). Epub 2022 Jun 21. PMID: 35884773

Article Published Date : Jun 20, 2022

Study Type : In Vitro Study

Additional Links

Substances : Chrysin

Diseases : Melanoma

Pharmacological Actions : Apoptotic, Autophagy Up-regulation

[+]

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ceska Slov Farm. 2016 ;65(1):10-14. PMID: 27118499

Article Published Date : Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2019 Jan ;52:117-128. Epub 2018 Sep 28. PMID: 30599890

Click here to read the entire abstract

Pubmed Data : Mol Biol Rep. 2015 Jan ;42(1):267-75. Epub 2014 Sep 28. PMID: 25262359

[+]

Cytotoxic activity of high dose ascorbic acid is enhanced by 2-deoxy-d-glucose in glycolytic melanoma cells.Feb 08, 2021

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2021 Feb 9 ;546:90-96. Epub 2021 Feb 9. PMID: 33578294

Article Published Date : Feb 08, 2021

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Melanoma

Pharmacological Actions : Chemotherapeutic

[+]

Cytotoxic effect of Ginkgo biloba kernel extract on HCT116 and A2058 cancer cell lines.Aug 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2022 Apr 23 ;27(9). Epub 2022 Apr 23. PMID: 35566081

Article Published Date : Apr 22, 2022

Study Type : In Vitro Study

Additional Links

Substances : Pine Needle

Diseases : Melanoma

Pharmacological Actions : Cytotoxic

Additional Keywords : Plant Extracts

[+]

Click here to read the entire abstract

Pubmed Data : Cell Death Dis. 2018 Oct 10 ;9(10):1039. Epub 2018 Oct 10. PMID: 30305604

Article Published Date : Oct 09, 2018

Study Type : In Vitro Study

Additional Links

Substances : Diosgenin

Diseases : Melanoma

Pharmacological Actions : Chemotherapeutic, Immunomodulatory

[+]

Effect of sulforaphane and 5-Aza-2'-deoxycytidine on melanoma cell growth.Jun 26, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicines (Basel). 2019 Jun 27 ;6(3). Epub 2019 Jun 27. PMID: 31252639

[+]

EGCG exerts significant anti-proliferative effects against renal cell cancer and malignant melanoma cells in vitro.May 19, 2009

Click here to read the entire abstract

Pubmed Data : J Clin Oncol. 2009 May 20 ;27(15_suppl):e22101. PMID: 27963498

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Cancer. 2015 May 26 ;112(11):1772-81. Epub 2015 May 5. PMID: 25942396

Article Published Date : May 25, 2015

Study Type : In Vitro Study

Additional Links

Diseases : Melanoma, Melanoma: Metastasis

[+]

Fucoidan exhibits anti-tumor activity against breast cancer and melanoma cells.Mar 31, 2012

Click here to read the entire abstract

Pubmed Data : Chem Biodivers. 2012 Apr ;9(4):817-28. PMID: 22492498

Article Published Date : Mar 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Fucoidan

Diseases : Breast Cancer, Melanoma

Pharmacological Actions : Antineoplastic Agents

[+]

Fucoidan has been shown to synergize with standard anti-cancer agents and reduces their side effects.Mar 13, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2017 Mar 14 ;8(11):17887-17896. PMID: 28060735

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2009 Oct 7;181(2):175-84. Epub 2009 Jul 3. PMID: 19577552

Article Published Date : Oct 07, 2009

Study Type : In Vitro Study

Additional Links

Substances : Gallic Acid

Diseases : Melanoma

Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor

[+]

Gamma-tocotrienol has broad therapeutic activity against human melanoma cells. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2009;61(3):357-66. PMID: 19373609

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2017 Mar 28 ;8(13):21674-21691. PMID: 28423510

Article Published Date : Mar 27, 2017

Study Type : In Vitro Study

Additional Links

Substances : Genistein

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic

Additional Keywords : Anti-metastatic, Genistein, melanoma

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View the Evidence: 498 Abstracts with Melanoma Research

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Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.Sep 25, 2016

Hypnotic drugs increase the risk of skin cancer.Sep 01, 2008

There is some evidence for the beneficial effects of regular coffee consumption on melanoma.Mar 31, 2016

Mineral oil exposures also contribute to the incidence and mortality of lung, melanoma, and possibly esophageal and stomach cancers and of non-Hodgkin's lymphoma in aerospace workers.Oct 01, 2005

A high vitamin D status may benefit prognosis in patients diagnosed with primary melanoma.Mar 22, 2017

consumption of caffeinated coffee was inversely associated with melanoma risk among men.Feb 19, 2017

Decreased vitamin D serum levels at melanoma diagnosis are associated with tumor ulceration and high tumor mitotic rate.Aug 27, 2019

Dl-alpha-tocopherol acetate does not protect against chemotherapy-induced chromosome damage and reduces the level of plasma gamma tocopherol.Feb 01, 2002

Evaluation of biodistribution of sulforaphane after administration of oral broccoli sprout extract in melanoma patients.Apr 23, 2018

Gerson therapy may have therapeutic efficacy in the treatment of melanoma patients.Sep 01, 1995

Increased UVA exposures (indoor light) and decreased cutaneous Vitamin D(3) levels may be responsible for the increasing incidence of melanoma.Apr 01, 2009

Melanoma skin cancer rates increased with decreased levels of vitamin D.Apr 30, 2017

Red and processed meat intake was inversely associated with melanoma risk in these two cohorts.Apr 22, 2018

Statin drug use is associated with increased incidence of melanoma and non-melanoma skin cancers. Oct 01, 2008

The authors of this study concluded that melanoma is associated with exposure to FM broadcasting.Jan 01, 2002

The Mediterranean Diet is associated with lower risk of skin cancer, Aug 05, 2019

The study suggests an augmented risk of cutaneous melanoma among subjects with exposure to pesticides.Mar 31, 2016

The use of sildenafil may be associated with a higher risk of melanoma in men.May 31, 2014

These results suggest that coffee drinking may protect against liver, ovarian, thyroid and endometrial cancers and melanoma.May 17, 2018

Vitamin D deficiency in melanoma patients is associated with worse overall survival.Dec 31, 2021

An extract of Rosmarinus officinals L. was able to efficiently reduce the proliferation of the human melanoma A375 cells.Dec 31, 2014

Antiproliferative and proapoptotic effects of erucin, a diet-derived H2S donor, on human melanoma cells.Dec 25, 2022

Apigenin is a novel therapeutic candidate for melanoma.Feb 13, 2017

Blue LED irradiation induces apoptotic cell death by activating the mitochondria-mediated pathway and reduces the early growth rate of melanoma cells.Dec 31, 2014

Delta tocotrienol might represent an effective option for chemopreventive strategies for melanoma.Dec 31, 2015

The combination of HSP70 with phloretin could be a novel treatment for efficient immunotherapy of intractable cancers such as skin melanoma.Dec 31, 2015

The present study shows that lichen compounds demonstrated strong antioxidant, antimicrobial, and anticancer properties.Oct 14, 2012

Zerumbone has chemotherapeutic effects on human melanoma cells by altering mitochondrial function.Mar 31, 2017

3,3'-Diindolylmethane improves antitumor immune responses of PD-1 blockade via inhibiting myeloid-derived suppressor cells.Jun 29, 2022

Blue light promotes vitamin C-mediated ferroptosis of melanoma through specifically upregulating transporter SVCT2 and generating Fe2.May 30, 2023

Capsaicin exerts therapeutic effects by targeting tNOX-SIRT1 axis and augmenting ROS-dependent autophagy in melanoma cancer cells.Dec 31, 2020

Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells.Sep 30, 2022

Ginsenoside Re inhibits melanogenesis and melanoma growth.Aug 31, 2023

Long-term survival and spontaneous tumor regression in stage IV melanoma.May 31, 2010

Olive leaf extract inhibits metastatic melanoma spread through suppression of epithelial to mesenchymal transition.Sep 30, 2022

Spontaneous regression of a middle ear melanoma. Sep 29, 2021

The use of Iscador as the sole modality for the adjuvant treatment of metastatic melanoma was extremely effective and very well tolerated achieving complete response and absence of all complaints.Apr 30, 2007

Viscum album extracts seems to have a positive potential in malignant cutaneous melanoma.Oct 31, 2017

Restoration of ascorbate from adequate to optimal physiological levels reduced tumor growth rates and moderated HIF-1 pathway activityJan 31, 2015

A lipid-soluble ginseng extract potently inhibited invasion and migration of B16F10 mouse melanoma cells in a dose-dependent manner.Dec 31, 2014

Altogether these data suggest M1 is an efficient candidate for melanoma therapy.Jan 31, 2016

An isocaloric carbohydrate restriction diet and natural AMPK activating agents induce synergistic anticancer effects.Mar 18, 2015

Angelica sinensis has therapeutic effect against melanoma cells in the mouse experimental model.Mar 01, 2007

Antioxidant, anti-inflammatory and antiproliferative effects of the Vitis vinifera L. var. Fetească Neagră and pinot noir pomace extracts. Dec 31, 2019

Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.May 31, 2019

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM.Nov 30, 2020

Apigenin limited melanoma cell growth and migration and induced a reduced angiogenic reaction limiting melanoma cell development.Dec 31, 2020

Approximately 67% of the initial number of mice survived with no tumor incidence based on macroscopic examination.May 29, 2006

Arctium lappa extract suppresses inflammation and inhibits melanoma progression.Jul 28, 2019

Ascorbate supplementation hinders metastasis, tumor growth and inflammatory cytokine secretion as well as enhanced encapsulation of tumors elicited by melanoma and breast cancer.Dec 31, 2012

Ascorbate supplementation might help reduce the severe side effects that arise from BETi therapy by reducing the dosage necessary for treatment.Nov 26, 2017

Assessment of antihyperlipidemic and antitumor effect of isolated active phytoconstituents from Apium graveolens.Dec 31, 2018

Bamboo leaf extract has immunopotentiating, antioxidant and antitumor activity. Jan 01, 2010

Berberine mediates tumor cell death by skewing tumor-associated immunosuppressive macrophages to inflammatory macrophages.Dec 21, 2021

Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells.Apr 18, 2004

Both ginseng saponins, 20(R)- and 20(S)-ginsenoside-Rg3, possess an ability to inhibit the lung metastasis of tumor cells.Aug 31, 1995

Cannabinoids as a potential new and novel treatment for melanoma.Feb 28, 2019

Cannabinoids inhibit the growth of melanoma cells but not of normal melanocytes.Nov 30, 2006

CARI III exerted anti-cancer activity that is comparable to doxorubicin against melanoma in vivo, as well as in vitro.Dec 31, 2013

Chrysin could be a potentially good candidate for future use in alternative anti-melanoma treatments.Jan 14, 2018

Chrysin enhances anti-tumor immunity response through IL-12-STAT4 signal pathway in B16F10 melanoma.Apr 27, 2022

Cinnamaldehyde enhances antimelanoma activity through covalently binding ENO1 and exhibits a promoting effect with dacarbazine.Jan 28, 2020

Cinnamon extract induces melanoma tumor cell death in an in vivo model. Jun 03, 2010

Codonopsis pilosula polysaccharide in synergy with dacarbazine inhibits mouse melanoma by repolarizing M2-like tumor-associated macrophages into M1-like tumor-associated macrophages.Aug 08, 2021

Comparable efficacy of fisetin and vemurafenib for inhibiting melanoma growth was noted in this study.Oct 23, 2018

Cordyceps has significant therapeutic action against melanoma cell growth in mice with no adverse side effects.Dec 01, 2004

Coupling to a cancer cell-specific antibody potentiates tumoricidal properties of curcumin.Aug 14, 2012

Crocin may exhibit significant melanoma tumor remission properties by positively modulating tumor growth related parameters.Dec 31, 2016

Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma.Feb 21, 2022

Curcumin and apigenin showed growth-suppressive and pro-apoptotic effects on melanoma cells.Oct 28, 2018

Curcumin effectively inhibited the proliferation of melanoma cells in vitro and in vivo.Nov 11, 2015

Curcumin exerts its in vitro anti-angiogenic and in vivo anti-tumour properties through combined PDE2 and PDE4 inhibition.Jan 31, 2015

Melanoma

View the Evidence:
498 Abstracts with Melanoma Research