Melasma

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16 Substances Researched for Melasma

Name	AC	CK
Pycnogenol (Pine Bark)	3	21
Silymarin	2	11
Ellagic Acid	1	10
Melatonin	1	10
Milk Thistle	1	10
Pine Bark Extract	1	10
Tomato	1	10
Vitamin C	1	10
Astragalus	1	1
Ginseng (Korean)	1	1
Grape Seed Extract	1	1
Niacinamide	1	1
Parsley	1	1
Resveratrol	1	1
Sesamol	1	1
Zinc	1	1

2 Therapeutic Actions Researched for Melasma

Name	AC	CK	Focus
Photobiomodulation	8	62
Laser Treatment: Yellow	1	10

Research Articles 20
Cumulative Knowledge Score 32
Overall Research Rating GOOD

View the Evidence:
20 Abstracts with Melasma Research

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Focus Your Research

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View the Evidence: 20 Abstracts with Melasma Research

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T. chebula 5% cream could be as effective as hydroquinone 2% cream in treating melasma with fewer side effects.Dec 31, 2023

A randomized, double-blind, split-face study of topical silymarin vs 2% hydroquinone cream in melasmas.Nov 30, 2022

Efficacy and safety of topical silymarin versus low fluence 1064-nm Q switched Nd:YAG laser in the treatment of melasma.Nov 30, 2021

Efficacy of 577 nm pro-yellow laser in the treatment of melasma.Feb 16, 2020

Efficacy of microneedling with topical vitamin C in the treatment of melasma.Feb 14, 2019

Ellagic acid significantly decreases the level of melanin in patients with melasma.Sep 01, 2008

Low-level laser therapy for skin rejuvenation: A safe and effective solution baked by data and visual evidence.May 29, 2024

Melatonin and oxidative stress in melasma - an unexplored territory; a prospective study.Mar 04, 2020

Pycnogenol is well-tolerated and increases the effectiveness of broad-spectrum sunscreen and the triple combination in the treatment of facial melasma in women.Aug 24, 2020

Pycnogenol was judged safe and therapeutically effective in patients suffering from melasma. Sep 01, 2002

The 675-nm wavelength for treating facial melasma.Jul 31, 2023

The effectiveness of tomato extract on superoxide dismutase (SOD) and severity degree of patients with melasma.May 31, 2022

The management of melasma on skin types V and VI using light emitting diode treatment.Sep 30, 2018

This pilot study shows that dermal melasma can be significantly improved with pulsed photobiomodulation.Mar 31, 2018

590 nm LED irradiation improved erythema through inhibiting angiogenesis of human microvascular endothelial cells and ameliorated pigmentation in melasma.Dec 06, 2022

Astragalus contains a compound, calycosin, which inhibits melanin biosynthesis without apparent cytotoxicity. Sep 01, 2010

Photobiomodulation for melasma treatment: Integrative review and state of the art.Dec 31, 2023

Resveratrol as a multifunctional topical hypopigmenting agent.Feb 21, 2019

Sesamol represents a new skin-whitening agent for use in cosmetics.Sep 30, 2015

Treatment of melasma: a review of less commonly used antioxidants.Aug 19, 2020

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Melasma

View the Evidence:
20 Abstracts with Melasma Research