Mitochondrial Diseases

Name	AC	CK
Coenzyme Q10	7	20
Resveratrol	7	20
Carnitine	4	16
Curcumin	8	14
Melatonin	7	13
Quercetin	7	13
Astaxanthin	9	11
Ubiquinol	1	10
Urolithin A	1	10
Alpha-Lipoic Acid	5	9
Ginsenosides	5	7
Flavonoids	5	6
Ginkgo biloba	5	6
Nicotinamide Mononucleotide	4	6
Rice Bran	3	6
Sulforaphane	4	6
Butyrate	1	5
Gingerol	2	5
Thymoquinone	3	5
Vitamin E	3	5
Acetyl-l-carnitine	1	4
Biotin	1	4
DHA (Docosahexaenoic Acid)	2	4
Honokiol	2	4
Hydrogen Water	2	4
Litchi	2	4
Niacin	1	4
Apigenin	2	3
Baicalein	2	3
EGCG (Epigallocatechin gallate)	2	3
Ginseng (Korean)	2	3
Gotu Kola	2	3
Huperzine	2	3
Lycopene	2	3
NAC (N-acetyl-L-cysteine)	2	3
Alpha Linolenic Acid	1	2
Amla Fruit	1	2
Anthocyanins	1	2
Apple Polyphenols	1	2
Arachidonic Acid	1	2
Astragaloside	2	2
Babchi	2	2
Bisdemethoxycurcumin	1	2
Blueberry	1	2
Caffeic acid phenethyl ester	1	2
Cannabidiol	1	2
Carnosine	1	2
Citrulline	1	2
Citrus naringin	1	2
Garlic	1	2
Genistein	1	2
Goji	1	2
Krill	1	2
Naringenin	2	2
Nettle	1	2
Oleuropein	1	2
Onion	1	2
Phloretin	1	2
Phlorotannins	2	2
Plantago	2	2
Polyphenols	2	2
Rooibos	2	2
Rosemaric Acid	1	2
Rutin	1	2
Selenium	2	2
Semecarpus anacardium	1	2
Sesamol	1	2
Spirulina	2	2
Thymol	1	2
Vitamin C	2	2
Vitamin K2	1	2
Vitexins	1	2
Bacopa	1	1
Bai Zhu	1	1
Bergamot	1	1
Beta-Caryophyllene	1	1
Catechin	1	1
Crocin	1	1
Cyanidin 3-glucoside	1	1
Elderberry	1	1
Emodin	1	1
Ferulic acid	1	1
Folic Acid	1	1
Fucoidan	1	1
Gastrodin	1	1
Grape Seed Extract	1	1
Hesperidin	1	1
Hydroxytyrosol	1	1
Icariin	1	1
Liquiritigenin	1	1
Luteolin	1	1
Mangiferin	1	1
Omega-3 Fatty Acids	1	1
Policosanol	1	1
Proanthocyanidins	1	1
Procyanidin B2	1	1
Pterostilbene	1	1
Puerarin	1	1
Schisandra	1	1
Seaweed: Brown	1	1
Tanshinone IIA	1	1
Tea	1	1
Vitamin B-12	1	1
Vitamin D	1	1

Name	AC	CK
Statin Drugs	12	63
Simvastatin	9	31
Atorvastatin	3	21
Sodium Fluoride	9	15
Thimerosal	2	15
Aspartame	1	12
Glucose	3	12
Aluminum	3	5
Chlorine	1	5
Fluoride	3	5
Gadolinium	1	5
Acetaminophen	2	4
Aluminum oxide	2	4
Cell Phone Exposure	2	4
Paracetamol	2	4
Pravastatin	2	4
Vaccine Adjuvants	2	4
Arsenic	2	3
Bisphenol A	2	3
Fructose	1	3
Glyphosate formulations	2	3
Lamivudine	1	3
Lovastatin	2	3
Tacrolimus	2	3
Bisphenol S	1	2
Clozapine	1	2
Fluoxetine (trade name Prozac)	1	2
Heavy Metals	1	2
Isoproterenol	1	2
Nanoparticles	1	2
Phthalates	1	2
Polystyrene nanoparticles	1	2
Rotenone	1	2
Antipsychotic Drugs	1	1
Chlorpyrifos	1	1
Dichloro-diphenyl-trichloroethane (DDT)	1	1
Dichlorodiphenyldichloroethylene (DDE)	1	1
Dioxins	1	1
Drug: Ciprofloxacin	1	1
Mercury	1	1
Roundup (herbicide)	1	1

Name	AC	CK
Exercise	9	32
Photobiomodulation	6	16
Dietary Modification: Low Carbohydrate/Ketogenic	3	14
Intravascular Laser Blood Irradiation	1	10
Infrared Light	2	2
Light Therapy	1	2
Light Therapy: Colored	1	1

Name	AC	CK
Electromagnetic Field Harms	7	26
Electromagnetic Radiation	7	26
Electromagnetic Radiation: 2.4 GHz	4	11
Microwave Radiation	4	11
Electromagnetic Radiation: 1.8 GHz	2	7
Mobile Phone Radiation	3	6
Vaccination: All	3	4
Wi-Fi Radiation	2	4
Blue Light (400−495 nm)	1	1

[+]

Mitochondrial dysfunction in autism spectrum disorders.Feb 29, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Psychiatry. 2012 Mar ;17(3):290-314. Epub 2011 Jan 25. PMID: 21263444

Article Published Date : Feb 29, 2012

Study Type : Meta Analysis, Review

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Diseases : Autism Spectrum Disorders, Mitochondrial Dysfunction

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Women preparing for pregnancy are suggested to reduce aspartame consumption and avoid oxidative stressors of the ovaries.Oct 21, 2022

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Pubmed Data : PLoS One. 2017 ;12(9):e0184832. Epub 2017 Sep 14. PMID: 28910366

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : DNA damage, Gulf War Syndrome, Mitochondrial Diseases

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Pubmed Data : Bioelectromagnetics. 2013 Dec ;34(8):618-29. Epub 2013 Sep 25. PMID: 24217848

Article Published Date : Dec 01, 2013

Study Type : Human In Vitro

Additional Links

Diseases : Mitochondrial Dysfunction

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Cytotoxic

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Radiofrequency-induced stress can damage mitochondria and induce elimination of damaged organelles via autophagy.Nov 01, 2014

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Pubmed Data : J Child Neurol. 2006 Feb ;21(2):170-2. PMID: 16566887

Article Published Date : Jan 31, 2006

Study Type : Human: Case Report

Additional Links

Diseases : Autism Spectrum Disorders, Mitochondrial Diseases

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Fatal exacerbation of peripheral neuropathy during lamivudine therapy has been reported.Aug 01, 2005

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Pubmed Data : Anaesthesia. 2005 Aug;60(8):806-10. PMID: 16029231

Article Published Date : Aug 01, 2005

Study Type : Human: Case Report

Additional Links

Diseases : Hepatitis B , Mitochondrial Diseases

Additional Keywords : Iatrogenic Disease

Problem Substances : Lamivudine

Adverse Pharmacological Actions : Cardiotoxic, Neurotoxic

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Fluoride exposure induces mitochondrial damage and mitophagy via activation of the IL-17A pathway in hepatocytes.Jan 14, 2022

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Pubmed Data : Sci Total Environ. 2022 Jan 15 ;804:150184. Epub 2021 Sep 8. PMID: 34517333

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Pubmed Data : Can J Cardiol. 2020 Apr 28. Epub 2020 Apr 28. PMID: 32360196

Article Published Date : Apr 27, 2020

Study Type : Human: Case Report

Additional Links

Diseases : Cardiomyopathy: Hypertrophic, Mitochondrial Diseases

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Antioxidants, Cardioprotective

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L-carnitine improves mitochondrial enzymes in heart and skeletal muscle of aged rats.Jan 01, 2005

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Pubmed Data : Exp Aging Res. 2005 Jan-Mar;31(1):55-67. PMID: 15842073

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Substances : Carnitine

Diseases : Aging, Mitochondrial Dysfunction

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3G cell phone exposure impacts brain function by inducing oxidative stress, DNA fragmentation, and apoptosis through the p38 MAPK pathway.Mar 01, 2014

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Pubmed Data : Cell Biochem Biophys. 2014 Mar ;68(2):347-58. PMID: 23949848

Article Published Date : Mar 01, 2014

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Pubmed Data : Neurochem Res. 2010 Feb 5. Epub 2010 Feb 5. PMID: 20131093

Article Published Date : Feb 05, 2010

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Mitochondrial Dysfunction , Prenatal Nutrition: Learning/Intelligence of Offspring

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Acacetin inhibits myocardial mitochondrial dysfunction.Feb 28, 2023

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Pubmed Data : J Nat Med. 2023 Mar ;77(2):262-275. Epub 2022 Dec 15. PMID: 36520340

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Pubmed Data : J Bioenerg Biomembr. 2020 Nov 6. Epub 2020 Nov 6. PMID: 33156468

Article Published Date : Nov 05, 2020

Study Type : Animal Study

Additional Links

Substances : Alpha Linolenic Acid

Diseases : Diabetes Mellitus: Type 2, Liver Damage, Mitochondrial Dysfunction

Additional Keywords : Risk Factors

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Aluminum nanoparticles are more neurotoxic than micrometer aluminum.Jun 01, 2018

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Pubmed Data : Biol Trace Elem Res. 2018 Jun ;183(2):261-269. Epub 2017 Aug 30. PMID: 28856594

Article Published Date : Jun 01, 2018

Study Type : Animal Study

Additional Links

Diseases : Lipid Peroxidation, Mitochondrial Dysfunction , Oxidative Stress

Additional Keywords : Vaccine Research

Problem Substances : Aluminum oxide, Vaccine Adjuvants

Adverse Pharmacological Actions : Glutathione Down-Regulation, Oxidant

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Amla prevents alcohol-induced brain mitochondrial dysfunction in rats.Jan 01, 2011

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Pubmed Data : J Med Food. 2011 Jan-Feb;14(1-2):62-8. Epub 2010 Dec 7. PMID: 21138366

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Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:9927864. Epub 2021 Nov 9. PMID: 34795844

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Mitochondrial Dysfunction

Pharmacological Actions : Antioxidants, Gastroprotective

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Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury.Mar 24, 2024

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Pubmed Data : J Transl Med. 2024 Mar 25 ;22(1):304. Epub 2024 Mar 25. PMID: 38528569

Article Published Date : Mar 24, 2024

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Inflammation, Mitochondrial Diseases, Oxidative Stress, Spinal Cord Injuries

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

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Citrulline/malate promotes aerobic energy production in human exercising muscle.Aug 01, 2002

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Pubmed Data : Br J Sports Med. 2002 Aug;36(4):282-9. PMID: 12145119

Article Published Date : Aug 01, 2002

Study Type : Animal Study

Additional Links

Substances : Citrulline

Diseases : Athletic Performance, Mitochondrial Dysfunction

[+]

Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle.Jan 31, 2019

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Exercise training can help minimize detrimental skeletal muscle aging deficits by improving mitochondrial protein quality control and biogenesis.May 09, 2012

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Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2012 May 9. Epub 2012 May 9. PMID: 22573103

Ginkgo biloba extract protects against aging-associated mitochondrial dysfunction in platelets and hippocampi of mice.Jan 01, 2010

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Pubmed Data : Platelets. 2010;21(5):373-9. PMID: 20459350

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Ginkgo biloba

Diseases : Aging, Aging: Brain , Mitochondrial Dysfunction

Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Neuroprotective Agents

Additional Keywords : Plant Extracts

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Ginseng extract reduces tacrolimus-induced oxidative stress by modulating autophagy in pancreatic beta cells.Jul 30, 2017

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Pubmed Data : Lab Invest. 2017 Jul 31. Epub 2017 Jul 31. PMID: 28759009

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Pubmed Data : Chin Herb Med. 2023 Apr ;15(2):231-239. Epub 2023 Mar 29. PMID: 37265773

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Pubmed Data : J Mol Neurosci. 2011 Mar ;43(3):284-9. Epub 2010 Aug 20. PMID: 20725867

Article Published Date : Mar 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Mitochondrial Dysfunction

Additional Keywords : brain health

Problem Substances : Aluminum, Heavy Metals

Adverse Pharmacological Actions : Neurotoxic, Oxidant

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Low dose of quercetin, both by itself or as a component in a red onion extract, increases energy expenditure and results in improvements in body composition and insulin sensitivity.Dec 31, 2014

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Pubmed Data : Genes Nutr. 2015 Jan ;10(1):451. Epub 2014 Dec 27. PMID: 25542303

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Pubmed Data : Food Funct. 2016 Jan ;7(1):508-15. PMID: 26569420

Article Published Date : Dec 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Litchi

Diseases : Liver Damage, Mitochondrial Dysfunction , Oxidative Stress

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Hepatoprotective, Superoxide Dismutase Up-regulation

Additional Keywords : Antioxidants, Catalase Up-Regulation, Litchi, liver damage, Mitochondrial Dysfunction, oxidative stress, Plant Extracts

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Lycopene prevents Di-(2-ethylhexyl) phthalate-induced mitophagy and oxidative stress in mice heart.Apr 30, 2023

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Pubmed Data : J Nutr Biochem. 2023 May ;115:109285. Epub 2023 Feb 14. PMID: 36796548

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Microwave exposure decreases mitochondrial membrane potential, increases DNA fragmentation, and induces apoptosis via a caspase-3-dependent pathway in vitro.Jan 01, 2014

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Pubmed Data : Int J Med Sci. 2014 ;11(5):426-35. Epub 2014 Mar 9. PMID: 24688304

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Pubmed Data : Nanomedicine. 2013 Feb ;9(2):212-21. Epub 2012 Jun 9. PMID: 22687898

Article Published Date : Feb 01, 2013

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Pubmed Data : J Transl Med. 2023 Dec 6 ;21(1):883. Epub 2023 Dec 6. PMID: 38057866

Article Published Date : Dec 05, 2023

Study Type : Animal Study

Additional Links

Substances : Nicotinamide Mononucleotide

Diseases : Inflammation, Mitochondrial Diseases, Sepsis

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents

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Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock.Sep 05, 2018

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Pubmed Data : Part Fibre Toxicol. 2023 Nov 22 ;20(1):44. Epub 2023 Nov 22. PMID: 37993864

Article Published Date : Nov 21, 2023

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Pubmed Data : Blood Press. 2010 Jun;19(3):196-205. PMID: 20429690

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Cardiomegaly, Hypertension, Mitochondrial Dysfunction

Additional Keywords : Mitochondrial Biogenesis, Stilbenes

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Rice bran extract is a promising candidate nutraceutical for the prevention of age-related neurodegenerative diseases.Aug 03, 2015

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Pubmed Data : Nutr Neurosci. 2015 Aug 4. Epub 2015 Aug 4. PMID: 26241203

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Pubmed Data : Chem Biol Interact. 2016 Jan 25 ;244:159-68. Epub 2015 Dec 22. PMID: 26721194

Article Published Date : Jan 24, 2016

Study Type : Animal Study

Additional Links

Substances : Thymol

Diseases : Mitochondrial Dysfunction , Myocardial Infarction, Oxidative Stress

Pharmacological Actions : Antioxidants

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Thymoquinone alleviates arsenic induced hippocampal toxicity and mitochondrial dysfunction.May 31, 2018

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Pubmed Data : J Ethnopharmacol. 2017 Feb 15. Epub 2017 Feb 15. PMID: 28214539

Article Published Date : Feb 14, 2017

Study Type : In Vitro Study

Additional Links

Substances : Elderberry

Diseases : Mitochondrial Dysfunction , Parkinson's Disease

Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation

Additional Keywords : Plant Extracts

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A subgroup of patients with mitochondrial disease may be at risk of autistic regression with fever.Apr 01, 2010

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Pubmed Data : J Child Neurol. 2010 Apr ;25(4):429-34. Epub 2009 Sep 22. PMID: 19773461

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Pubmed Data : J Cell Biochem. 2014 Aug ;115(8):1403-11. PMID: 24700636

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Pubmed Data : BMC Neurol. 2015 Mar 1 ;15:19. Epub 2015 Mar 1. PMID: 25884176

Article Published Date : Feb 28, 2015

Study Type : In Vitro Study

Additional Links

Substances : Nicotinamide Mononucleotide

Diseases : Alzheimer's Disease, Mitochondrial Dysfunction , Neurodegenerative Diseases

Pharmacological Actions : Neuroprotective Agents

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Effects of bergamot polyphenols on mitochondrial dysfunction and sarcoplasmic reticulum stress in diabetic cardiomyopathy.Jul 19, 2021

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Pubmed Data : Nutrients. 2021 Jul 20 ;13(7). Epub 2021 Jul 20. PMID: 34371986

Article Published Date : Jul 19, 2021

Study Type : Review

Additional Links

Substances : Bergamot, Polyphenols

Diseases : Cardiomyopathy, Diabetes: Cardiovascular Illness, Mitochondrial Dysfunction

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective

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Exercise has a protective effect in metabolic disorders. Nov 30, 2015

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Pubmed Data : Med Hypotheses. 2015 Dec ;85(6):707-9. Epub 2015 Oct 26. PMID: 26527493

Article Published Date : Nov 30, 2015

Study Type : Commentary, Review

Additional Links

Diseases : Inflammation, Metabolic Diseases, Mitochondrial Dysfunction

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents, Cytoprotective

[+]

Fluoride-induced mitochondrial dysfunction.Feb 29, 2024

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Pubmed Data : Biol Trace Elem Res. 2024 Mar ;202(3):835-849. Epub 2023 Jun 10. PMID: 37300595

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Pubmed Data : J Food Biochem. 2020 Jan 14:e13147. Epub 2020 Jan 14. PMID: 31943241

Article Published Date : Jan 13, 2020

Study Type : In Vitro Study

Additional Links

Substances : Grape Seed Extract, Proanthocyanidins

Diseases : Hydrogen Peroxide Induced Toxicity, Mitochondrial Dysfunction

Pharmacological Actions : Anti-Apoptotic, Antioxidants

[+]

Hesperidin alleviates insulin resistance by improving HG-induced oxidative stress and mitochondrial dysfunction by restoring miR-149.Apr 28, 2021

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Pubmed Data : J Pineal Res. 2012 Oct 12. Epub 2012 Oct 12. PMID: 23137057

Article Published Date : Oct 11, 2012

Study Type : Review

Additional Links

Substances : Melatonin

Diseases : Mitochondrial Diseases, Mitochondrial Dysfunction

Additional Keywords : Evolutionary Biology, Origin Of Melatonin

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Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation.May 31, 2020

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Pubmed Data : Transl Neurodegener. 2020 Jun 1 ;9(1):19. Epub 2020 Jun 1. PMID: 32475349

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Pubmed Data : Biol Pharm Bull. 2014 ;37(2):217-25. Epub 2013 Nov 12. PMID: 24225258

Article Published Date : Dec 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Ginkgo biloba

Diseases : Brain Ischemia, Mitochondrial Dysfunction , Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Neuroprotective mechanisms of dieckol against glutamate toxicity.Feb 28, 2019

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Pubmed Data : BMC Complement Altern Med. 2014 Oct 3 ;14:370. Epub 2014 Oct 3. PMID: 25277760

Article Published Date : Oct 02, 2014

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Pubmed Data : Metab Brain Dis. 2021 Dec ;36(8):2377-2391. Epub 2021 Aug 2. PMID: 34338973

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Pubmed Data : iScience. 2023 Jul 21 ;26(7):107113. Epub 2023 Jun 14. PMID: 37416477

Tanshinone IIa protects retinal endothelial cells against mitochondrial fission induced by methylglyoxal through glyoxalase 1.Aug 14, 2019

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Pubmed Data : Eur J Pharmacol. 2019 Aug 15 ;857:172419. Epub 2019 May 25. PMID: 31136758

Article Published Date : Aug 14, 2019

Study Type : In Vitro Study

Additional Links

Substances : Tanshinone IIA

Diseases : Advanced Glycation End products (AGE), Diabetic Retinopathy, Mitochondrial Dysfunction

Pharmacological Actions : Antioxidants

[+]

Targeting mitochondria with folic acid and vitamin B12 ameliorates nicotine mediated islet cell dysfunction.Aug 31, 2018

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Pubmed Data : Environ Toxicol. 2018 Sep ;33(9):988-1000. Epub 2018 Jul 4. PMID: 29972271

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Pubmed Data : Phytomedicine. 2018 Sep 19 ;54:224-230. Epub 2018 Sep 19. PMID: 30668372

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Pubmed Data : Mar Drugs. 2019 Sep 2 ;17(9). Epub 2019 Sep 2. PMID: 31480724

Article Published Date : Sep 01, 2019

Study Type : In Vitro Study

Additional Links

Substances : Fucoidan

Diseases : Mitochondrial Diseases, Parkinson's Disease

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

These findings might recommend the use of ginsenoside Rg1 in preventing and treating isoflurane-induced neurotoxicity.Jan 31, 2015

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Pubmed Data : Biomed Environ Sci. 2015 Feb ;28(2):116-26. PMID: 25716562

Article Published Date : Jan 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Mitochondrial Dysfunction , Surgery: Anesthesiology

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

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This article underpins the mechanisms of mitochondrial dysfunction in Alzheimer's disease. These include altered mitochondrial bioenergetics.Jan 11, 2016

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Pubmed Data : Mol Neurobiol. 2016 11 ;53(9):6078-6090. Epub 2015 Nov 4. PMID: 26537901

Article Published Date : Jan 11, 2016

Study Type : Review

Additional Links

Diseases : Mitochondrial Dysfunction , Oxidative Stress

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This evidence suggests that mercury may be either causal or contributory in the brain pathology in autism spectrum disorder.Jan 01, 2012

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Pubmed Data : Acta Neurobiol Exp (Wars). 2012 ;72(2):113-53. PMID: 22810216

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Pubmed Data : Nutrients. 2015;7(7):5764-5782. Epub 2015 Jul 15. PMID: 26184304

Article Published Date : Dec 31, 2014

Study Type : Review

Additional Links

Substances : Ferulic acid

Diseases : Alzheimer's Disease, Brain: Oxidative Stress, Mitochondrial Dysfunction

Pharmacological Actions : Antioxidants, Neuroprotective Agents

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Toxoplasma gondii infection is associated with mitochondrial dysfunction in-vitro.Dec 31, 2016

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Mitochondrial dysfunction in autism spectrum disorders.Feb 29, 2012

Women preparing for pregnancy are suggested to reduce aspartame consumption and avoid oxidative stressors of the ovaries.Oct 21, 2022

A subpopulation of eight individuals from four of the families showed thimerosal hypersensitivity.Dec 31, 2012

Amelioration of hypercholesterolemia and fatigue by ubiquinol-10 supplementation.Dec 31, 2012

Decreased skeletal muscle mitochondrial DNA in patients treated with high-dose simvastatin has been observed.May 01, 2007

Effects of intravascular laser irradiation of blood in mitochondria dysfunction and oxidative stress in adults with chronic spinal cord injury.Sep 30, 2012

Epidemiology of autism spectrum disorder in Portugal: prevalence, clinical characterization, and medical conditions.Sep 30, 2007

Mitochondrial disease is prevalent among children with autism spectrum disorder and may correlate with severity.Jan 01, 2015

Mitochondrial dysfunction caused by statin contributes to endothelial dysfunction in patients with coronary artery disease.Jun 01, 2010

Mitochrondrial dysfunction associated with carnitine deficiency may play a role in idiopathic inflammatory myopathy. Dec 01, 2007

Resveratrol and exercise combined to treat functional limitations in late life.Oct 13, 2020

Statin drugs lead to changes in statin sterol metabolism and aggressive statin treatment may adversely effect mitochondrial volume.Jul 01, 2005

Statin therapy can be associated with high blood lactate/ pyruvate ratio suggestive of mitochondrial dysfunction. Sep 01, 1996

Statins appear to cause muscle damage and impair oxidative metabolism.Jan 01, 2004

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans.May 31, 2019

There is increased mitochondrial oxidative damage in patients with sporadic amyotrophic lateral sclerosisApr 15, 2008

These results expand our understanding of human adaptation to a ketogenic diet combined with exercise.Sep 27, 2020

Veterans with gulf war illness exhibit greater mitochondrial DNA damage which is consistent with mitochondrial dysfunction.Dec 31, 2016

Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function.Nov 23, 2021

1950 MHz induces mitochondrial damage and apoptosis in astrocytes.Jan 01, 2012

2.1 GHz microwave radiation decreases cell viability, reduces mitochondrial membrane potential, and results in cell death in breast fibroblast cells in vitro.Jan 01, 2013

Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism.Jan 01, 2018

Chlorine induces bioenergetic dysfunction associated with lung inflammation.Jul 31, 2015

Findings suggest that the epidemiological link between environmental mercury exposure and an increased risk of developing autism may be mediated through mitochondrial dysfunction.Dec 31, 2014

High glucose levels spike reactive oxygen species production by mitochondria and neuron apoptosis.Nov 01, 2002

Hyperglycemia induces mitochondrial dysfunction by a O-GlcNAc-independent mechanism.Apr 01, 2015

Low intensity static magnetic fields increase cellular free radical content and decrease mitochondrial membrane potential.Dec 01, 2013

Radiofrequency-induced stress can damage mitochondria and induce elimination of damaged organelles via autophagy.Nov 01, 2014

These results demonstrate a toxic effect of gadolinium-containing MRI contrast agents on mitochondrial respiratory function and cell viability.Jul 31, 2019

6-Gingerol alleviates ectopic lipid deposition in skeletal muscle by regulating CD36 translocation and mitochondrial function.May 13, 2024

Developmental regression and mitochondrial dysfunction in a child with autism.Jan 31, 2006

Fatal exacerbation of peripheral neuropathy during lamivudine therapy has been reported.Aug 01, 2005

Fluoride exposure induces mitochondrial damage and mitophagy via activation of the IL-17A pathway in hepatocytes.Jan 14, 2022

Simvastatin-induced lactic acidosis has been reported.Oct 01, 2002

Statins-induced MELAS syndrome has been reported. Jan 01, 2007

This case report suggests that a ketogenic diet may improve hypertrophic cardiomyopathy in the context of mitochondrial disease. Apr 27, 2020

L-carnitine improves mitochondrial enzymes in heart and skeletal muscle of aged rats.Jan 01, 2005

3G cell phone exposure impacts brain function by inducing oxidative stress, DNA fragmentation, and apoptosis through the p38 MAPK pathway.Mar 01, 2014

6-Gingerol improves ectopic lipid accumulation, mitochondrial dysfunction, and insulin resistance in skeletal muscle of ageing rats.Dec 31, 2018

810-nm photobiomodulation evokes glutamate release in normal and rotenone-dysfunctional cortical nerve terminals by modulating mitochondrial energy metabolism.Jan 06, 2025

A combination of mitochondrial targeting nutrients may improve skeletal mitochondrial dysfunction and exert hypoglycemic effects, without causing weight gain.Jan 01, 2008

A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats.Dec 31, 2019

A wolfberry (goji) preparation prevents prenatal stress-induced cognitive impairment of offspring rats and inhibits oxidative damage and mitochondrial dysfunction. Feb 05, 2010

Acacetin inhibits myocardial mitochondrial dysfunction.Feb 28, 2023

Acetaminophen could cause transient mitochondrial dysfunction that may synergize with other stresses to promote liver damage and steatosis.Dec 30, 2015

Acetyl-L-carnitine and lipoic acid decrease age-related oxidative insult in the mitochondria of the rat heart. Apr 01, 2002

Administration of rutin could effectively improve aging-related metabolic dysfunction.Jan 24, 2016

Alpha-linolenic acid helped in controlling glycaemia in rats induced to T2DM.Nov 05, 2020

Aluminum nanoparticles are more neurotoxic than micrometer aluminum.Jun 01, 2018

Amla prevents alcohol-induced brain mitochondrial dysfunction in rats.Jan 01, 2011

Apigenin ameliorated the obesity-induced skeletal muscle atrophy by attenuating mitochondrial dysfunction.Oct 01, 2017

Apple peel polyphenols reduce mitochondrial dysfunction in mice with DSS-induced ulcerative colitis.Mar 20, 2018

Arachidonic Acid and docosahexaenoic acid prevent alcoholic fatty liver and mitochondrial dysfunction in the ratAug 01, 2008

Astaxanthin attenuates d-galactose-induced brain aging in rats.Apr 27, 2020

Astaxanthin positively modulates age-associated mitochondrial dysfunction in healthy dogs.Oct 15, 2012

Bisdemethoxycurcumin protects small intestine from lipopolysaccharide-induced mitochondrial dysfunction.Dec 31, 2020

Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury.Mar 24, 2024

Carnitine induces autophagy and restores high-fat diet-induced mitochondrial dysfunction.Sep 27, 2017

Cationic nanoplastic causes mitochondrial dysfunction in neural progenitor cells and impairs hippocampal neurogenesis.Oct 31, 2023

Centella asiatica attenuates hippocampal mitochondrial dysfunction and improves memory and executive function in β-amyloid overexpressing mice.Jan 11, 2018

Chronic treatment with baicalein alleviates behavioural disorders and improves cerebral blood flow.Feb 28, 2023

Citrulline/malate promotes aerobic energy production in human exercising muscle.Aug 01, 2002

Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle.Jan 31, 2019

CoQ10 ameliorates mitochondrial dysfunction in diabetic nephropathy through mitophagy.Dec 31, 2018

Curcumin attenuates indomethacin-induced oxidative stress and mitochondrial dysfunction.Jul 01, 2008

Curcumin micelles might be a suitable formulation for the prevention of mitochondrial dysfunction in brain aging and neurodegeneration.Aug 04, 2015

Curcumin treatment attenuates ischemic stroke-induced brain injury via activation of SIRT1.Nov 26, 2015

Diesel exhaust induces mitochondrial dysfunction, hyperlipidemia, and liver steatosis.Aug 31, 2019

Docosahexaenoic acid attenuates mitochondrial alterations and oxidative stress leading to cell death Induced by very long-chain fatty acids.Jan 17, 2020

Effect of glyphosate on rat liver mitochondria in vivo.May 31, 1979

Electromagnetic radiation 2450 MHz exposure causes cognition deficit with mitochondrial dysfunction and activation of intrinsic pathway of apoptosis in rats.May 31, 2018

Exercise training can help minimize detrimental skeletal muscle aging deficits by improving mitochondrial protein quality control and biogenesis.May 09, 2012

Mitochondrial Diseases

View the Evidence:
269 Abstracts with Mitochondrial Diseases Research