Mitochondrial Myopathies

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1 Substances Researched for Mitochondrial Myopathies

Name	AC	CK	Focus
Schisandra	1	1

8 Problem Substances Researched for Mitochondrial Myopathies

Name	AC	CK
Statin Drugs	6	43
Simvastatin	5	15
Atorvastatin	2	12
Lovastatin	2	11
Cerivastatin	1	2
Fluvastatin	1	2
Fluoxetine (trade name Prozac)	1	1
Statin	1	1

Research Articles 11
Cumulative Knowledge Score 17
Overall Research Rating GOOD

View the Evidence:
11 Abstracts with Mitochondrial Myopathies Research

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Statin drugs impair mitochondrial function and decrease ubiquinone (coenzyme Q10) levels. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Toxicol Mech Methods. 2009 Jan;19(1):44-50. PMID: 19778232

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Diseases : Mitochondrial Myopathies, Statin-Induced Pathologies

Problem Substances : Lovastatin, Statin Drugs

[+]

Statin drugs lead to changes in statin sterol metabolism and aggressive statin treatment may adversely effect mitochondrial volume.Jul 01, 2005

Click here to read the entire abstract

Pubmed Data : Clin Pharmacol Ther. 2005 Jul;78(1):60-8. PMID: 16003294

Article Published Date : Jul 01, 2005

Study Type : Human Study

Additional Links

Diseases : Mitochondrial Dysfunction , Mitochondrial Myopathies, Myopathies

Problem Substances : Atorvastatin, Simvastatin, Statin Drugs

[+]

Statin-related myopathy is associated wtih low muscle levels of coenzyme Q10. Nov 01, 2005

Click here to read the entire abstract

Pubmed Data : Arch Neurol. 2005 Nov;62(11):1709-12. PMID: 16286544

Article Published Date : Nov 01, 2005

Study Type : Human Study

Additional Links

Diseases : Mitochondrial Myopathies, Myopathy, Statin-Induced Pathologies

Problem Substances : Statin Drugs

[+]

Statins appear to cause muscle damage and impair oxidative metabolism.Jan 01, 2004

Click here to read the entire abstract

Pubmed Data : J Submicrosc Cytol Pathol. 2004 Jan ;36(1):85-9. PMID: 15311678

Article Published Date : Jan 01, 2004

Study Type : Human Study

Additional Links

Diseases : Mitochondrial Dysfunction , Mitochondrial Myopathies, Myopathies, Statin-Induced Pathologies

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Myotoxicity

[+]

Lipophilic statin drugs are associated with impaired skeletal muscle mitochondria.Oct 01, 2006

Click here to read the entire abstract

Pubmed Data : Cell Mol Life Sci. 2006 Oct;63(19-20):2415-25. PMID: 17013560

Article Published Date : Oct 01, 2006

Study Type : Animal Study

Additional Links

Diseases : Mitochondrial Myopathies, Statin-Induced Pathologies

Problem Substances : Atorvastatin, Cerivastatin, Fluvastatin, Simvastatin, Statin Drugs

[+]

Fluoxetine may harm mitochondria.Jul 04, 2016

Click here to read the entire abstract

Pubmed Data : Toxicol Lett. 2016 Jul 5 ;258:185-191. Epub 2016 Jul 5. PMID: 27392437

Article Published Date : Jul 04, 2016

Study Type : Review

Additional Links

Diseases : Mitochondrial Diseases, Mitochondrial Dysfunction , Mitochondrial Myopathies

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Schisandra berry's reputation as "Qi-invigorating" has a biochemical basis in the fact that it improves mitochondrial antioxidant status. Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2006;34(2):171-6. PMID: 16552829

Article Published Date : Jan 01, 2006

Study Type : Commentary

Additional Links

Substances : Schisandra

Diseases : Mitochondrial Dysfunction , Mitochondrial Myopathies

Additional Keywords : Qi-Invigoration

[+]

Simvastatin-induced inhibition of mitochondrial respiration is likely associated myotoxicity. Aug 04, 2011

Click here to read the entire abstract

Pubmed Data : Biochim Biophys Acta. 2011 Aug 4. Epub 2011 Aug 4. PMID: 21839782

Article Published Date : Aug 04, 2011

Study Type : In Vitro Study

Additional Links

Diseases : Drug-Induced Nutrient Depletion: Statin Drugs, Mitochondrial Dysfunction , Mitochondrial Myopathies

Problem Substances : Simvastatin

Adverse Pharmacological Actions : Myotoxicity

[+]

Statin drugs can act directly on mitochondria either in vivo or in vitro inducing permeability transition, which is a process involved in cell death.Feb 15, 2006

Click here to read the entire abstract

Pubmed Data : Toxicology. 2006 Feb 15 ;219(1-3):124-32. Epub 2005 Dec 15. PMID: 16343726

Article Published Date : Feb 15, 2006

Study Type : Review

Additional Links

Diseases : Mitochondrial Dysfunction , Mitochondrial Myopathies

Problem Substances : Lovastatin, Simvastatin, Statin Drugs

Adverse Pharmacological Actions : Cytotoxic

[+]

Statins alter mitochondrial function which may be associated with myotoxicity in skeletal muscle.Apr 15, 2005

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2005 Apr 15 ;329(3):1067-75. PMID: 15752763

Article Published Date : Apr 15, 2005

Study Type : In Vitro Study

Additional Links

Diseases : Mitochondrial Dysfunction , Mitochondrial Myopathies, Statin-Induced Pathologies

Problem Substances : Simvastatin

Adverse Pharmacological Actions : Myotoxicity

[+]

Statins may have mitochondria and cardiac cell damaging properties. Feb 01, 2024

Click here to read the entire abstract

Pubmed Data : Basic Res Cardiol. 2024 Feb 2. Epub 2024 Feb 2. PMID: 38305903

Article Published Date : Feb 01, 2024

Study Type : In Vitro Study

Additional Links

Diseases : Cardiovascular Disease, Mitochondrial Myopathies

Problem Substances : Statin

Adverse Pharmacological Actions : Cardiotoxic

Research Articles 11
Cumulative Knowledge Score 17
Overall Research Rating GOOD

Mitochondrial Myopathies Related Articles

Exercise Stops The Mitochondrial Aging Process In Its Tracks

Written by Sayer Ji, Founder

As we age, mitochondrial density (the number of mitochondria per cell), and mitochondrial quality (its genetic and structural integrity) decline. This is largely due to stress, environmental radiation and chemical exposures, prescribed drugs, nutritional deficiencies, imbalances and/or incompatibilities, and mitochondrial DNA defects inherited maternally, but is also a natural part of getting older.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 11 Abstracts with Mitochondrial Myopathies Research

Limited to Members Only

Currently Available Sorting Options

Statin drugs impair mitochondrial function and decrease ubiquinone (coenzyme Q10) levels. Jan 01, 2009

Statin drugs lead to changes in statin sterol metabolism and aggressive statin treatment may adversely effect mitochondrial volume.Jul 01, 2005

Statin-related myopathy is associated wtih low muscle levels of coenzyme Q10. Nov 01, 2005

Statins appear to cause muscle damage and impair oxidative metabolism.Jan 01, 2004

Lipophilic statin drugs are associated with impaired skeletal muscle mitochondria.Oct 01, 2006

Fluoxetine may harm mitochondria.Jul 04, 2016

Schisandra berry's reputation as "Qi-invigorating" has a biochemical basis in the fact that it improves mitochondrial antioxidant status. Jan 01, 2006

Simvastatin-induced inhibition of mitochondrial respiration is likely associated myotoxicity. Aug 04, 2011

Statin drugs can act directly on mitochondria either in vivo or in vitro inducing permeability transition, which is a process involved in cell death.Feb 15, 2006

Statins alter mitochondrial function which may be associated with myotoxicity in skeletal muscle.Apr 15, 2005

Statins may have mitochondria and cardiac cell damaging properties. Feb 01, 2024

Mitochondrial Myopathies Related Articles

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Mitochondrial Myopathies

View the Evidence:
11 Abstracts with Mitochondrial Myopathies Research