Muscle Disorders

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4 Substances Researched for Muscle Disorders

Name	AC	CK	Focus
Alpha-Lipoic Acid	1	2
Glycyrrhiza uralensis	1	1
Parthenolide	1	1
Tanshinone IIA	1	1

2 Problem Substances Researched for Muscle Disorders

Name	AC	CK	Focus
Statin Drugs	2	20
Pravastatin	1	3

2 Therapeutic Actions Researched for Muscle Disorders

Name	AC	CK	Focus
Pilates	1	10
Photobiomodulation	3	6

Research Articles 11
Cumulative Knowledge Score 17
Overall Research Rating GOOD

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11 Abstracts with Muscle Disorders Research

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Muscular symptoms were reported by 832 patients (10.5%), with a median time of onset of 1 month following initiation of statin therapy.Dec 01, 2005

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Pubmed Data : Cardiovasc Drugs Ther. 2005 Dec ;19(6):403-14. PMID: 16453090

Article Published Date : Dec 01, 2005

Study Type : Human Study

Additional Links

Diseases : Muscle Disorders, Myalgias, Statin-Induced Pathologies

Problem Substances : Statin Drugs

[+]

Pilates may improve muscle endurance, flexibility, balance, and posture.Mar 01, 2010

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Pubmed Data : J Strength Cond Res. 2010 Mar;24(3):661-7. PMID: 20145572

Article Published Date : Mar 01, 2010

Study Type : Human Study

Additional Links

Diseases : Muscle Disorders, Posture Disorders

Therapeutic Actions : Pilates

[+]

Review: muscle symptoms associated with lipid-lowering drugs.Sep 01, 2003

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Pubmed Data : Cardiovasc Drugs Ther. 2003 Sep-Nov;17(5-6):459-65. PMID: 15107601

Article Published Date : Sep 01, 2003

Study Type : Human Study

Additional Links

Diseases : Muscle Disorders, Muscle Fatigue, Myalgias, Statin-Induced Pathologies

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Myotoxicity

[+]

Pravastatin-associated polymyositis has been reported. Jan 01, 2004

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Pubmed Data : Rinsho Shinkeigaku. 2004 Jan ;44(1):25-7. PMID: 15199734

Article Published Date : Jan 01, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Muscle Disorders, Polymyositis

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Pravastatin

Adverse Pharmacological Actions : Myotoxicity

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Evaluation of inflammatory biomarkers associated with oxidative stress and histological assessment of low-level laser therapy in experimental myopathy.Jul 31, 2010

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Pubmed Data : Lasers Surg Med. 2010 Aug ;42(6):577-83. PMID: 20662035

Article Published Date : Jul 31, 2010

Study Type : Animal Study

Additional Links

Diseases : Muscle Disorders, Oxidative Stress

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Superoxide Dismutase Up-regulation

[+]

Low level laser therapy on experimental myopathy.Dec 31, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Laser Ther. 2011 ;20(4):287-92. PMID: 24155539

Article Published Date : Dec 31, 2010

Study Type : Animal Study

Additional Links

Diseases : Muscle Disorders

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Nitric Oxide Inhibitor

[+]

Low-level laser therapy prevents treadmill exercise-induced progression of arthrogenic joint contracture.May 31, 2019

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Pubmed Data : Inflammation. 2019 Jun ;42(3):857-873. PMID: 30506108

Article Published Date : May 31, 2019

Study Type : Animal Study

Additional Links

Diseases : Inflammation, Muscle Disorders

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Treatment with lipoic acid has shown effects on the redistribution of muscle fibers, and can prevent atrophy in slow and fast diabetic muscle.Jun 27, 2017

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Pubmed Data : J Endocrinol Invest. 2017 Jun 28. Epub 2017 Jun 28. PMID: 28660607

Article Published Date : Jun 27, 2017

Study Type : Animal Study

Additional Links

Substances : Alpha-Lipoic Acid

Diseases : Diabetes Mellitus: Type 1, Diabetic Complications, Muscle Disorders

Pharmacological Actions : Antioxidants

[+]

G. uralensis-extracted components might be useful therapeutic agents for the management of muscle-associated diseases.Jan 15, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2021 Jan 16 ;22(2). Epub 2021 Jan 16. PMID: 33467209

Article Published Date : Jan 15, 2021

Study Type : In Vitro Study

Additional Links

Substances : Glycyrrhiza uralensis

Diseases : Muscle Disorders

Pharmacological Actions : Regenerative

Additional Keywords : Muscle Regeneration, Plant Extracts

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Parthenolide regulates oxidative stress-induced mitophagy and suppresses apoptosis through p53 signaling pathway in C2C12 myoblasts.Aug 31, 2019

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Pubmed Data : J Cell Biochem. 2019 Sep ;120(9):15695-15708. Epub 2019 May 29. PMID: 31144365

Article Published Date : Aug 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Parthenolide

Diseases : Muscle Disorders

Pharmacological Actions : Anti-Apoptotic, Antioxidants

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Tanshinone IIA promotes the proliferation and differentiation ability of primary muscle stem cells via MAPK and Akt signaling.Nov 09, 2023

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Pubmed Data : Biochem Biophys Res Commun. 2023 Nov 10 ;689:149235. Epub 2023 Nov 10. PMID: 37976834

Article Published Date : Nov 09, 2023

Study Type : In Vitro Study

Additional Links

Substances : Tanshinone IIA

Diseases : Muscle Disorders

Additional Keywords : Muscle Regeneration

Copyright: elenabsl / 123RF Stock Photo

Research Articles 11
Cumulative Knowledge Score 17
Overall Research Rating GOOD

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