Necrotising enterocolitis

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17 Substances Researched for Necrotising enterocolitis
NameACCKFocus
Probiotics771Locked
Lactoferrin441Locked
Arginine212Locked
Lactobacillus rhamnosus GG212Locked
DHA (Docosahexaenoic Acid)110Locked
Lactobacillus Acidophilus110Locked
Lactobacillus paracasei110Locked
Lactobacillus rhamnosus 110Locked
Zinc110Locked
Astaxanthin12Locked
Curcumin12Locked
Ginger12Locked
Glutamine12Locked
Lactobacillus reuteri12Locked
Melatonin12Locked
Astragaloside11Locked
Breast Milk 11Locked
1 Problem Substances Researched for Necrotising enterocolitis
NameACCKFocus
Infant Formula846Locked
1 Therapeutic Actions Researched for Necrotising enterocolitis
NameACCKFocus
Breastfeeding11Locked

View the Evidence:
37 Abstracts with Necrotising enterocolitis Research

[+]

Enteral lactoferrin supplementation for preventing sepsis and necrotizing enterocolitis in preterm infants.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:1186. Epub 2020 Aug 7. PMID: 32848789
Article Published Date : Dec 31, 2019
Study Type : Meta Analysis
Additional Links
Substances : Lactoferrin
Diseases : Necrotising enterocolitis, Sepsis
Pharmacological Actions : Gastrointestinal Agents
[+]

Probiotics significantly reduced necrotizing enterocolitis. Sep 25, 2017

Pubmed Data : Pediatr Res. 2017 Sep 26. Epub 2017 Sep 26. PMID: 28949953
Article Published Date : Sep 25, 2017
Study Type : Meta Analysis
Additional Links
Substances : Probiotics
Diseases : Necrotising enterocolitis
Pharmacological Actions : Gastrointestinal Agents
[+]

A daily dose of docosahexaenoic acid for 14 days starting with the first enteral feed may prevent necrotizing enterocolitis in preterm infants.Feb 16, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Feb 17 ;13(2). Epub 2021 Feb 17. PMID: 33671220
Article Published Date : Feb 16, 2021
Study Type : Human Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Necrotising enterocolitis
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Risk Reduction
[+]

Bovine lactoferrin supplementation for prevention of necrotizing enterocolitis in very-low-birth-weight neonates.Feb 28, 2014

Pubmed Data : Early Hum Dev. 2014 Mar ;90 Suppl 1:S60-5. PMID: 24709463
Article Published Date : Feb 28, 2014
Study Type : Human Study
Additional Links
Substances : Lactobacillus rhamnosus , Lactoferrin
Diseases : Necrotising enterocolitis
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Risk Reduction
[+]

Current evidence indicates that lactoferrin could significantly reduce the incidence of necrotizing enterocolitis and late-onset sepsis.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2018 Aug ;97(35):e11976. PMID: 30170397
Article Published Date : Jul 31, 2018
Study Type : Human Study
Additional Links
Substances : Lactoferrin
Diseases : Necrotising enterocolitis, Sepsis
Pharmacological Actions : Prophylactic Agents
Additional Keywords : Risk Reduction
[+]

Electrical grounding improves vagal tone in preterm infants. Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neonatology. 2017 ;112(2):187-192. Epub 2017 Jun 10. PMID: 28601861
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Necrotising enterocolitis, Premature Birth
Therapeutic Actions : Grounding: Contact with the Earth
Pharmacological Actions : Prophylactic Agents
Additional Keywords : Risk Reduction
[+]

Enteral supplementation of probiotics prevents severe necrotizing enterocolitis and all-cause mortality in preterm infants.Mar 15, 2011

Pubmed Data : Cochrane Database Syst Rev. 2011 Mar 16(3):CD005496. Epub 2011 Mar 16. PMID: 21412889
Article Published Date : Mar 15, 2011
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Necrotising enterocolitis, Premature Birth
[+]

Enterobacter sakazakii (ES) is an emerging pathogen associated with the ingestion of contaminated reconstituted formula that causes necrotizing enterocolitis, sepsis, and meningitis in low-birth-weight preterm neonatal infants.Oct 01, 2008

Pubmed Data : Surg Infect (Larchmt). 2008 Oct;9(5):533-9. PMID: 18687047
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Diseases : Bacterial Meningitis, Enterobacteriaceae Infections, Infant Nutrition: Infant Formula, Infants: Low Birth Weight, Necrotising enterocolitis, Premature Birth, Sepsis
Problem Substances : Infant Formula
[+]

Infant formula use is associated with an increased risk for necrotising entercolitis in preterm and low birth weight infants. Jan 01, 2007

Pubmed Data : Cochrane Database Syst Rev. 2007(4):CD002971. Epub 2007 Oct 17. PMID: 17943776
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Diseases : Infant Nutrition: Infant Formula, Infants: Low Birth Weight, Necrotising enterocolitis, Preterm Infant Care
Problem Substances : Infant Formula
[+]

Intravenous nutrition given to at-risk premature infants may result in zinc deficiency and consequent adverse health effects.Jul 01, 2010

Pubmed Data : Pediatr Dermatol. 2010 Jul-Aug;27(4):380-3. PMID: 20653858
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Substances : Zinc
Diseases : Enteropathy, Necrotising enterocolitis, Premature Birth, Zinc Deficiency
[+]

Lactobacillus paracasei subsp. paracasei F19 in Bell's stage 2 of necrotizing enterocolitis.Jul 31, 2013

Pubmed Data : Minerva Pediatr. 2013 Aug ;65(4):353-60. PMID: 24051968
Article Published Date : Jul 31, 2013
Study Type : Human Study
Additional Links
Substances : Lactobacillus paracasei
Diseases : Necrotising enterocolitis
[+]

Necrotising enterocolitis during the first week of life can be prevented through exclusive breastfeeding. Aug 01, 2008

Pubmed Data : J Perinatol. 2008 Aug;28(8):556-60. Epub 2008 Mar 27. PMID: 18368057
Article Published Date : Aug 01, 2008
Study Type : Human Study
Additional Links
Diseases : Necrotising enterocolitis
Problem Substances : Infant Formula
[+]

Probiotic supplementation reduces the frequency of necrotising enterocolitis in preterm neonates with very low birth weight.Aug 31, 2016

Pubmed Data : J Coll Physicians Surg Pak. 2016 Sep ;26(9):770-4. PMID: 27671183
Article Published Date : Aug 31, 2016
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Necrotising enterocolitis
Additional Keywords : Risk Reduction
[+]

Probiotics can be used to prevent necrotising enterocolitis and nosocomial infection in very low birth weight preterm infants.Mar 31, 2017

Pubmed Data : Br J Nutr. 2017 Apr ;117(7):994-1000. Epub 2017 Apr 26. PMID: 28443531
Article Published Date : Mar 31, 2017
Study Type : Human Study
Additional Links
Substances : Lactobacillus Acidophilus, Lactobacillus rhamnosus GG, Probiotics
Diseases : Infants: Low Birth Weight, Necrotising enterocolitis, Sepsis
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Gastrointestinal Agents, Infants: Low Birth Weight, Lactobacillus Acidophilus, Lactobacillus rhamnosus GG, Necrotising enterocolitis, probiotics, Risk Reduction, sepsis
[+]

Probiotics contribute to the prevention of necrotising enterocolitis in preterm neonates with very low birthweight. May 12, 2007

Pubmed Data : Lancet. 2007 May 12;369(9573):1614-20. PMID: 17499603
Article Published Date : May 12, 2007
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Infants: Very Low Birth Weight/Low Birth Weight, Necrotising enterocolitis, Premature Birth
[+]

Probiotics to prevent necrotising enterocolitis in very preterm infants.Feb 29, 2016

Pubmed Data : Dan Med J. 2016 Mar ;63(3). PMID: 26931192
Article Published Date : Feb 29, 2016
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Necrotising enterocolitis, Premature Birth
[+]

Safety Study: There is no increase in neurodevelopmental disability in preterm infants who received L-arginine supplementation.Apr 01, 2009

Pubmed Data : J Paediatr Child Health. 2009 Apr;45(4):219-23. Epub 2009 Mar 23. PMID: 19320804
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Substances : Arginine
Diseases : Necrotising enterocolitis
[+]

The use of hydrolyzed formula may be associated with enterocolitis syndrome in infants. Dec 01, 2007

Pubmed Data : Allergol Int. 2007 Dec;56(4):473-6. Epub 2007 Nov 1. PMID: 17965587
Article Published Date : Dec 01, 2007
Study Type : Human Study
Additional Links
Diseases : Infant Nutrition: Infant Formula, Necrotising enterocolitis
Problem Substances : Infant Formula
[+]

Astaxanthin reduces the severity of intestinal damage in a neonatal rat model of necrotizing enterocolitis.Apr 13, 2021

Pubmed Data : Am J Perinatol. 2021 Apr 14. Epub 2021 Apr 14. PMID: 33853144
Article Published Date : Apr 13, 2021
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Necrotising enterocolitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin protects against necrotizing enterocolitis in neonatal rats.Feb 01, 2010

Pubmed Data : Zhongguo Dang Dai Er Ke Za Zhi. 2010 Feb;12(2):132-6. PMID: 20199731
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Infant Infections, Necrotising enterocolitis
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-10 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginger therapy efficiently ameliorated the severity of intestinal damage in necrotizing enterocolitis and may be a promising treatment option.Jul 09, 2018

Pubmed Data : J Ethnopharmacol. 2018 Jul 10. Epub 2018 Jul 10. PMID: 30005955
Article Published Date : Jul 09, 2018
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Necrotising enterocolitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Glutamine and arginine supplementation may help prevent necrotizing enterocolitis.Jul 01, 2009

Pubmed Data : J Pediatr Gastroenterol Nutr. 2009 Jul;49(1):85-9. PMID: 19503000
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Arginine, Glutamine
Diseases : Necrotising enterocolitis
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
[+]

Infant formula induces mucosal dysfunction, bacterial proliferation, and necrotizing enterocolitis in preterm pigsNov 01, 2008

Pubmed Data : Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G1092-103. Epub 2008 Sep 25. PMID: 18818317
Article Published Date : Nov 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Infant Nutrition: Infant Formula, Intestinal Permeability , Necrotising enterocolitis, Premature Birth
Problem Substances : Infant Formula
[+]

Melatonin alleviates neonatal necrotizing enterocolitis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gastroenterol Res Pract. 2022 ;2022:6920577. Epub 2022 Mar 17. PMID: 35340691
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Necrotising enterocolitis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Necrotising enterocolitis-like intestinal injury is ameliorated by Lactobacillus rhamnosus GG in parallel with SIGIRR and A20 induction in neonatal mice.Feb 12, 2020

Pubmed Data : Pediatr Res. 2020 Feb 13. Epub 2020 Feb 13. PMID: 32053825
Article Published Date : Feb 12, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG
Diseases : Necrotising enterocolitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Preterm birth makes the intestine sensitive to infant-formula induced intestinal atrophy in a pig experimental model. Oct 01, 2005

Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2005 Oct;289(4):R1212-22. Epub 2005 Jun 16. PMID: 15961526
Article Published Date : Oct 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Infant Nutrition: Infant Formula, Necrotising enterocolitis, Premature Birth
Problem Substances : Infant Formula
[+]

Protective effect of Lactobacillus reuteri against oxidative stress in neonatal mice with necrotizing enterocolitis.Oct 29, 2019

Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2019 Oct 30 ;39(10):1221-1226. PMID: 31801706
Article Published Date : Oct 29, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Necrotising enterocolitis, Oxidative Stress
Pharmacological Actions : Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sulforaphane ameliorates the intestinal injury in necrotizing enterocolitis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Can J Gastroenterol Hepatol. 2022 ;2022:6529842. Epub 2022 May 11. PMID: 35600210
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Necrotising enterocolitis
Pharmacological Actions : anti-inflammatory, Gastroprotective, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sumac for the prevention and treatment of necrotizing enterocolitis.Nov 30, 2019

Pubmed Data : J Food Biochem. 2019 Dec ;43(12):e13068. Epub 2019 Oct 3. PMID: 31583737
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Sumac
Diseases : Necrotising enterocolitis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

The protective effect of sulforaphane on ER-induced apoptosis and inflamamiton in necrotizing enterocolitis.Jul 04, 2022

Pubmed Data : Comb Chem High Throughput Screen. 2022 Jul 5. Epub 2022 Jul 5. PMID: 35792122
Article Published Date : Jul 04, 2022
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Necrotising enterocolitis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antibacterial and anti-inflammatory effects of Lactobacillus reuteri in its biofilm state.Jun 30, 2022

Pubmed Data : J Pediatr Surg. 2022 Jul ;57(7):1382-1390. Epub 2021 Sep 20. PMID: 34657737
Article Published Date : Jun 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Necrotising enterocolitis
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents
[+]

Astragaloside IV ameliorates necrotizing enterocolitis.Sep 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 Oct ;12(4):2702-2708. Epub 2016 Aug 30. PMID: 27698775
Article Published Date : Sep 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Necrotising enterocolitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, NF-kappaB Inhibitor
[+]

Digested formula but not digested fresh human milk causes death of intestinal cells in vitro: implications for necrotizing enterocolitis.Nov 30, 2012

Pubmed Data : Pediatr Res. 2012 Dec ;72(6):560-7. Epub 2012 Sep 24. PMID: 23007028
Article Published Date : Nov 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Breast Milk
Diseases : Infant Chemical Exposures, Infant Nutrition: Infant Formula, Necrotising enterocolitis
Therapeutic Actions : Breastfeeding
Problem Substances : Infant Formula
Adverse Pharmacological Actions : Cytotoxic
[+]

Infant formual may contain the bacteria Enterobacter sakazakii which has been associated with cases of meningitis, necrotizing enterocolitis and sepsis in premature and full-term infants.May 01, 2008

Pubmed Data : J Int Med Res. 2008 May-Jun;36(3):394-9. PMID: 18534120
Article Published Date : May 01, 2008
Study Type : Commentary
Additional Links
Diseases : Bacterial Meningitis, Infant Infections, Infant Nutrition: Infant Formula, Necrotising enterocolitis, Premature Birth, Sepsis
Problem Substances : Infant Formula
[+]

Lactoferrin and necrotizing enterocolitis.Mar 31, 2014

Pubmed Data : Curr Opin Pediatr. 2014 Apr ;26(2):146-50. PMID: 24503532
Article Published Date : Mar 31, 2014
Study Type : Review
Additional Links
Substances : Lactoferrin
Diseases : Inflammation, Necrotising enterocolitis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Probiotics and the prevention of necrotizing enterocolitis.Feb 28, 2019

Pubmed Data : J Pediatr Surg. 2019 Mar ;54(3):405-412. Epub 2018 Sep 6. PMID: 30241961
Article Published Date : Feb 28, 2019
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Necrotising enterocolitis, Premature Birth
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The emerging role of exosomes in the pathogenesis, prognosis and treatment of necrotizing enterocolitis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2020 ;12(11):7020-7033. Epub 2020 Nov 15. PMID: 33312348
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Necrotising enterocolitis
Additional Keywords : Exosomes

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