Neurodevelopmental Disorders

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11 Substances Researched for Neurodevelopmental Disorders
NameACCKFocus
Folic Acid 23Locked
Vitamin B-1223Locked
Alpha-Lipoic Acid12Locked
Probiotics12Locked
Quercetin12Locked
Vitamin B-612Locked
Vitamin C12Locked
Vitamin D12Locked
Astragaloside11Locked
Ferulic acid11Locked
Taurine11Locked
27 Problem Substances Researched for Neurodevelopmental Disorders
NameACCKFocus
Thimerosal 25207Locked
Bisphenol A 854Locked
Phthalates431Locked
Mercury230Locked
Pesticides322Locked
Bisphenol F212Locked
Bisphenol S212Locked
Chlorpyrifos212Locked
Endocrine Disrupting Chemicals (EDCs)312Locked
Acetaminophen211Locked
Paracetamol211Locked
Heavy Metals110Locked
Organophosphate Pesticides110Locked
Aluminum Chloride12Locked
Aluminum11Locked
Aspartame11Locked
Brilliant Blue FCF11Locked
Ethanol11Locked
Infant Formula11Locked
L-glutamic Acid11Locked
Lead11Locked
Organophosphates11Locked
Polybrominated diphenylethers (PBDEs)11Locked
Polychlorinated biphenyls (PCBs)11Locked
Quinoline Yellow11Locked
Statin Drugs11Locked
Triclosan11Locked
2 Therapeutic Actions Researched for Neurodevelopmental Disorders
NameACCKFocus
Breastfeeding11Locked
Melodic Intonation Therapy 11Locked
7 Problematic Actions Researched for Neurodevelopmental Disorders
NameACCKFocus
Vaccination: Haemophilus Influenzae220Locked
Vaccination: Hepatitis B110Locked
Mobile Phone Radiation24Locked
Vaccination: All12Locked
Vaccination: Animal Model12Locked
Vaccination: Diphtheria-Pertussis-Tetanus12Locked
Wi-Fi Radiation12Locked

View the Evidence:
74 Abstracts with Neurodevelopmental Disorders Research

[+]

As thimerosal was removed from childhood vaccines, the number of neurodevelopmental disorders decreased in the US.Jun 01, 2006

Pubmed Data : Med Sci Monit. 2006 Jun;12(6):CR231-9. Epub 2006 May 29. PMID: 16733480
Article Published Date : Jun 01, 2006
Study Type : Meta Analysis
Additional Links
Diseases : Childhood Chemical Exposures, Neurodevelopmental Disorders, Vaccine-induced Toxicity
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Exposure to mercury from thimerosal-containing vaccines was associcated with an increased risk of neurodevelopmental problems in infants from 1992-1997.Apr 01, 2005

Pubmed Data : Med Sci Monit. 2005 Apr;11(4):CR160-70. Epub 2005 Mar 24. PMID: 15795695
Article Published Date : Apr 01, 2005
Study Type : Meta Analysis
Additional Links
Diseases : Attention Deficit Disorder, Learning disorders, Neurodevelopmental Disorders, Seizures, Speech Disorders, Tic Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Rates of autism, speech disorders, mental retardation, infantile spasms, and thinking abnormalities were higher in children exposured to higher thimerosal levels.Aug 01, 2006

Pubmed Data : J Toxicol Environ Health A. 2006 Aug;69(15):1481-95. PMID: 16766480
Article Published Date : Aug 01, 2006
Study Type : Meta Analysis
Additional Links
Diseases : Autism, Cognitive Decline/Dysfunction, Infantile Spasms, Mental Retardation, Neurodevelopmental Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimersol exposure in infants significantly increases neurodevelopment disorders in infants, e.g. autism, autism spectrum disorders, tics, attention deficit disorder, and emotional disturbances.Aug 15, 2008

Pubmed Data : J Neurol Sci. 2008 Aug 15;271(1-2):110-8. Epub 2008 May 15. PMID: 18482737
Article Published Date : Aug 15, 2008
Study Type : Meta Analysis
Additional Links
Diseases : Attention Deficit Disorder, Autism, Autism Spectrum Disorders, Emotional Disorders, Neurodevelopmental Disorders
Problem Substances : Mercury, Thimerosal
[+]

Thimersol exposure is associated with tics and delayed language acquisition in infants.Nov 01, 2003

Pubmed Data : Pediatrics. 2003 Nov;112(5):1039-48. PMID: 14595043
Article Published Date : Nov 01, 2003
Study Type : Meta Analysis
Additional Links
Diseases : Learning disorders, Neurodevelopmental Disorders, Tic Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Administration of thimerosal-containing vaccines in the United States resulted in a significant number of children developing neurodevelopmental disorders.Nov 01, 2004

Pubmed Data : Int J Toxicol. 2004 Nov-Dec;23(6):369-76. PMID: 15764492
Article Published Date : Nov 01, 2004
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Neurodevelopmental Disorders
Problem Substances : Thimerosal
[+]

Adverse neurodevelopmental effects were associated with early childhood chlorpyrifos exposure.May 09, 2019

Pubmed Data : Environ Pollut. 2019 May 10 ;251:538-546. Epub 2019 May 10. PMID: 31108286
Article Published Date : May 09, 2019
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Pesticide Toxicity
Problem Substances : Chlorpyrifos
[+]

Children with autism have a diminished methylation capacity leading to higher sustained levels of oxidation stress, due to deficiencies in glutathioneNov 30, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2004 Dec ;80(6):1611-7. PMID: 15585776
Article Published Date : Nov 30, 2004
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Neurodevelopmental Disorders, Oxidative Stress
Additional Keywords : Genomic Variation, Impaired Methylation Capacity
[+]

Deficient maternal vitamin D status in pregnancy may have adverse effects on some measures of motor and social development in children under 4 years.Jul 11, 2017

Pubmed Data : Br J Nutr. 2017 Jul 12:1-11. Epub 2017 Jul 12. PMID: 28697816
Article Published Date : Jul 11, 2017
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Early life exposure to indoor air pollutants and the risk of neurodevelopmental delays.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2022 01 ;158:107004. Epub 2021 Nov 26. PMID: 34991264
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Neurodevelopmental Disorders
Additional Keywords : Risk Factors
[+]

Early prenatal exposure to suspected endocrine disruptor mixtures is associated with lower IQ at age seven.Oct 18, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 Oct 19:105185. Epub 2019 Oct 19. PMID: 31668669
Article Published Date : Oct 18, 2019
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A , Bisphenol F, Endocrine Disrupting Chemicals (EDCs)
[+]

Higher total DEP and total DAP metabolite levels from the mother at week 28 of gestation were significantly associated with reduced motor composite scores.May 26, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2017 May 27 ;14(6). Epub 2017 May 27. PMID: 28554999
Article Published Date : May 26, 2017
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Pesticide Toxicity , Prenatal Chemical Exposures
Problem Substances : Organophosphate Pesticides
[+]

Increasing organic Hg exposure from Thimerosal-containing vaccines increased the subsequent risk of pervasive developmental disorder diagnosis.Jan 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Trace Elem Res. 2015 Feb ;163(1-2):28-38. Epub 2014 Nov 11. PMID: 25382662
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Vaccination: Haemophilus Influenzae
Problem Substances : Thimerosal
[+]

Maternal exposure to several EDCs was associated with adverse neurodevelopmental performances among the children aged 1-2years.Dec 15, 2017

Pubmed Data : Sci Total Environ. 2017 Dec 16 ;624:377-384. Epub 2017 Dec 16. PMID: 29258038
Article Published Date : Dec 15, 2017
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders
Problem Substances : Bisphenol A , Heavy Metals, Pesticides, Phthalates
[+]

Mothers receiving thimerosal via Rho(D) immune globulin injection saw a significantly higher rate of autism in the children exposed to mercury in utero. Mar 31, 2008

Pubmed Data : Neuro Endocrinol Lett. 2008 Apr ;29(2):272-80. PMID: 18404135
Article Published Date : Mar 31, 2008
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Developmental Disorder: Children, Neurodevelopmental Disorders
Additional Keywords : Rh-negative, Risk Factors
Problem Substances : Thimerosal
[+]

Organic-Hg exposure from thimerosal-containing hepatitis B vaccine led to an increased risk of neurodevelopmental disorder diagnosis.Aug 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2014 Sep ;11(9):9156-70. Epub 2014 Sep 5. PMID: 25198681
Article Published Date : Aug 31, 2014
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Neurodevelopmental Disorders
Additional Keywords : Increased Risk
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Paternal and maternal preconception concentrations of some phthalate biomarkers were associated with specific aspects of child behaviour.Jul 20, 2017

Pubmed Data : Environ Res. 2017 Jul 21 ;158:720-728. Epub 2017 Jul 21. PMID: 28738300
Article Published Date : Jul 20, 2017
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Phthalate exposure and neurodevelopmental outcomes in early school age children from Poland.Nov 30, 2019

Pubmed Data : Environ Res. 2019 Dec ;179(Pt B):108829. Epub 2019 Oct 18. PMID: 31677502
Article Published Date : Nov 30, 2019
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Neurotoxic
[+]

Prenatal paracetamol exposure and child neurodevelopment.Nov 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Epidemiol. 2013 Dec ;42(6):1702-13. Epub 2013 Oct 24. PMID: 24163279
Article Published Date : Nov 30, 2013
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity , Neurodevelopmental Disorders, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Acetaminophen, Paracetamol
[+]

Prenatal urinary BPA concentration was associated with some aspects of child behavior in this cohort.Jun 15, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2017 Jun 16 ;125(6):067008. Epub 2017 Jun 16. PMID: 28657891
Article Published Date : Jun 15, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Neurodevelopmental Disorders, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
[+]

The occurrence of neurodevelopmental disorders following thimerosal-containing childhood vaccines does not appear to be coincidental.Mar 31, 2003

Pubmed Data : Pediatr Rehabil. 2003 Apr-Jun;6(2):97-102. PMID: 14534046
Article Published Date : Mar 31, 2003
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Neurodevelopmental Disorders
Problem Substances : Thimerosal
[+]

There is an association between neurodevelopmental disorders and thimerosal-containing vaccines.Jun 01, 2003

Pubmed Data : Exp Biol Med (Maywood). 2003 Jun;228(6):660-4. PMID: 12773696
Article Published Date : Jun 01, 2003
Study Type : Human Study
Additional Links
Diseases : Autism, Mental Retardation, Neurodevelopmental Disorders
Problem Substances : Thimerosal
[+]

These results provide evidence that prenatal exposure to BPA and BPS may affect child neurodevelopment.Nov 27, 2019

Pubmed Data : J Hazard Mater. 2019 Nov 28:121774. Epub 2019 Nov 28. PMID: 32001102
Article Published Date : Nov 27, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Neurodevelopmental Disorders, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Bisphenol S
[+]

This regional study identified higher rates of developmental delay diagnoses in an area with aerial pesticides application.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pediatr. 2017 ;5:116. Epub 2017 May 24. PMID: 28596952
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Pesticide Toxicity
Problem Substances : Pesticides
[+]

This study found a significant increase in neurodevelopmental delays related to the combined exposure to methylmercury and ethylmercury.Jan 06, 2016

Pubmed Data : Environ Res. 2016 Jan 7. Epub 2016 Jan 7. PMID: 26774584
Article Published Date : Jan 06, 2016
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders
Additional Keywords : Toxic Substance Synergy
Problem Substances : Mercury, Thimerosal
[+]

This study found potential impacts of prenatal BPA exposure on childhood neurodevelopment at 12 and 24 months of age, especially among girls.Apr 09, 2019

Pubmed Data : Int J Hyg Environ Health. 2019 Apr 10. Epub 2019 Apr 10. PMID: 30981646
Article Published Date : Apr 09, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Neurodevelopmental Disorders
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Neurotoxic
[+]

This study provides suggestive evidence of an association between thimerosal and neurodevelopmental outcomes.Mar 13, 2018

Pubmed Data : Int J Hyg Environ Health. 2018 Mar 14. Epub 2018 Mar 14. PMID: 29573974
Article Published Date : Mar 13, 2018
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders
Anti Therapeutic Actions : Vaccination: Haemophilus Influenzae
Problem Substances : Thimerosal
[+]

This study supports an association between increasing exposure from thimerosal containing childhood vaccines and the subsequent risk of specific delays in development among males and females.Sep 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : N Am J Med Sci. 2014 Oct ;6(10):519-31. PMID: 25489565
Article Published Date : Sep 30, 2014
Study Type : Human Study
Additional Links
Diseases : Autoimmune Diseases, Neurodevelopmental Disorders
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
[+]

Alcohol induced molecular dysregulation in human embryonic stem cell-derived neural Precursor cells.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016;11(9):e0163812. Epub 2016 Sep 28. PMID: 27682028
Article Published Date : Dec 31, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Alcohol Toxicity , Fetal Growth Retardation, Neurodevelopmental Disorders
[+]

Alpha lipoic acid may protect against mercurial-induced abnormal behaviours.Feb 22, 2018

Pubmed Data : Neurotoxicol Teratol. 2018 Feb 23. Epub 2018 Feb 23. PMID: 29481853
Article Published Date : Feb 22, 2018
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Autism, Neurodevelopmental Disorders
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Thimerosal
[+]

Alteration of adaptive behaviors of progeny after maternal mobile phone exposure.Mar 31, 2018

Pubmed Data : Environ Sci Pollut Res Int. 2018 Apr ;25(11):10894-10903. Epub 2018 Feb 3. PMID: 29397508
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Neurodevelopmental Disorders
Anti Therapeutic Actions : Mobile Phone Radiation
[+]

Aluminum chloride exposure may cause embryonic developmental disorder in zebrafish and ab-normal neurobehaviour in juvenile fish.Mar 19, 2017

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2017 Mar 20 ;35(3):166-170. PMID: 28511298
Article Published Date : Mar 19, 2017
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Neurodevelopmental Disorders
Problem Substances : Aluminum Chloride
[+]

Bisphenol F exposure impairs neurodevelopment in zebrafish larvae.Oct 31, 2019

Pubmed Data : Ecotoxicol Environ Saf. 2019 Nov 1 ;188:109870. Epub 2019 Nov 1. PMID: 31683046
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Neurodevelopmental Disorders
Problem Substances : Bisphenol F
Adverse Pharmacological Actions : Neurotoxic
[+]

Data demonstrates a negative neurodevelopmental impact of perinatal exposure to thimerosal.May 31, 2012

Pubmed Data : Cerebellum. 2012 Jun ;11(2):575-86. PMID: 22015705
Article Published Date : May 31, 2012
Study Type : Animal Study
Additional Links
Diseases : Learning disorders, Neurodevelopmental Disorders, Oxidative Stress
Additional Keywords : Ethylmercury
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Developmental exposures to ultrafine particle air pollution reduces early testosterone levels and adult male social novelty preference.Aug 22, 2018

Pubmed Data : Neurotoxicology. 2018 Aug 23 ;68:203-211. Epub 2018 Aug 23. PMID: 30144459
Article Published Date : Aug 22, 2018
Study Type : Animal Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Neurodevelopmental Disorders
Additional Keywords : Risk Factors
[+]

Embryonic atrazine exposure alters zebrafish and human miRNAs associated with angiogenesis, cancer, and neurodevelopment.Nov 30, 2016

Pubmed Data : Food Chem Toxicol. 2016 Dec ;98(Pt A):25-33. Epub 2016 Apr 1. PMID: 27046698
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Cancers: All, Neurodevelopmental Disorders, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Pesticides
[+]

Gestational B-vitamin supplementation alleviates PM2.5-induced autism-like behavior and hippocampal neurodevelopmental impairment in mice offspring.Dec 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2019 Dec 15 ;185:109686. Epub 2019 Sep 20. PMID: 31546205
Article Published Date : Dec 14, 2019
Study Type : Animal Study
Additional Links
Substances : Folic Acid , Vitamin B-12, Vitamin B-6
Diseases : Air Pollution Linked Toxicity, Autism Spectrum Disorders, Neurodevelopmental Disorders, Prenatal Chemical Exposures
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Risk Reduction
[+]

Impaired innate and conditioned social behavior in adult C57Bl6/J mice prenatally exposed to chlorpyrifos.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Brain Funct. 2019 Mar 1 ;15(1):2. Epub 2019 Mar 1. PMID: 30823929
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Diseases : Neurodevelopmental Disorders, Pesticide Toxicity , Prenatal Chemical Exposures
Problem Substances : Chlorpyrifos
[+]

Long-term exposure of zebrafish to bisphenol F: Adverse effects on parental reproduction and offspring neurodevelopment.May 08, 2022

Pubmed Data : Aquat Toxicol. 2022 May 9 ;248:106190. Epub 2022 May 9. PMID: 35561629
Article Published Date : May 08, 2022
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Neurodevelopmental Disorders, Prenatal Chemical Exposures
Problem Substances : Bisphenol F
Adverse Pharmacological Actions : Neurotoxic
[+]

Luteolin treatment ameliorates brain development and behavioral performance in a mouse model of CDKL5 deficiency disorder.Aug 04, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Aug 5 ;23(15). Epub 2022 Aug 5. PMID: 35955854
Article Published Date : Aug 04, 2022
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Neurodevelopmental Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Neurogenesis
[+]

Maturational changes in amygdala volume and the binding capacity of an opioid antagonist in the amygdala was significantly altered in infant macaques receiving the vaccine schedule. Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Neurobiol Exp (Wars). 2010 ;70(2):147-64. PMID: 20628439
Article Published Date : Dec 31, 2009
Study Type : Animal Study
Additional Links
Diseases : Amygdala: Damage/Abnormalities, Neurodevelopmental Disorders, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Animal Model
Problem Substances : Thimerosal
[+]

Perinatal exposure to glyphosate-based herbicides induced neurodevelopmental behaviors impairments.Jun 23, 2022

Pubmed Data : Int J Dev Neurosci. 2022 Jun 24. Epub 2022 Jun 24. PMID: 35750327
Article Published Date : Jun 23, 2022
Study Type : Animal Study
Additional Links
Diseases : Brain: Oxidative Stress, Glyphosate Toxicity, Neurodevelopmental Disorders, Prenatal Chemical Exposures
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Neurotoxic
[+]

Perinatal exposure to paracetamol: Dose and sex-dependent effects in behaviour and brain's oxidative stress markers in progeny.Jun 24, 2021

Pubmed Data : Behav Brain Res. 2021 Jun 25 ;408:113294. Epub 2021 Apr 6. PMID: 33836167
Article Published Date : Jun 24, 2021
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity , Neurodevelopmental Disorders, Oxidative Stress, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Acetaminophen, Paracetamol
Adverse Pharmacological Actions : Neurotoxic
[+]

Probiotic treatment may relieve specific behavioral abnormalities associated with neurodevelopmental disorders.Jun 15, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell. 2016 Jun 16 ;165(7):1762-75. PMID: 27315483
Article Published Date : Jun 15, 2016
Study Type : Animal Study
Additional Links
Substances : Probiotics
Diseases : Autism Spectrum Disorders, Dysbiosis, High Fat Diet, Neurodevelopmental Disorders
Additional Keywords : Transgenerational Epigenetic Modification
[+]

Quercetin and vitamin C have protective effects on the neurodevelopmental toxicity induced by maternal air pollution exposure.Sep 06, 2018

Pubmed Data : Chemosphere. 2018 Sep 7 ;213:182-196. Epub 2018 Sep 7. PMID: 30218877
Article Published Date : Sep 06, 2018
Study Type : Animal Study
Additional Links
Substances : Quercetin, Vitamin C
Diseases : Air Pollution Linked Toxicity, Neurodevelopmental Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

The current study revealed that maternal exposure to WiFi radiofrequencies led to various adverse neurological effects in the offspring of animals.May 31, 2017

Pubmed Data : Environ Toxicol Pharmacol. 2017 Jun ;52:239-247. Epub 2017 Apr 22. PMID: 28458069
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Brain: Oxidative Stress, Neurodevelopmental Disorders
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Mobile Phone Radiation, Wi-Fi Radiation
Adverse Pharmacological Actions : Neurotoxic
[+]

These findings implicate a genetic influence in autistic disorders and provides a model for investigating thimerosal related neurotoxicity.Aug 31, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Psychiatry. 2004 Sep ;9(9):833-45. PMID: 15184908
Article Published Date : Aug 31, 2004
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders, Autoimmune Diseases, Neurodevelopmental Disorders
Additional Keywords : Genomic Variation
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

These results show that BPA-free products are not necessarily safer and support the removal of all bisphenols from consumer merchandise.Feb 02, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2015 Feb 3 ;112(5):1475-80. Epub 2015 Jan 12. PMID: 25583509
Article Published Date : Feb 02, 2015
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Neurodevelopmental Disorders
Problem Substances : Bisphenol A , Bisphenol S
Adverse Pharmacological Actions : Neurotoxic
[+]

This study raised serious concerns about adverse neurodevelopmental disorders such as autism in humans after thimerosal containing vaccines.Oct 31, 2013

Pubmed Data : World J Pediatr. 2013 Nov ;9(4):356-60. Epub 2013 Nov 14. PMID: 24235069
Article Published Date : Oct 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Autism, Neurodevelopmental Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

VAERS had significantly higher ORs than autism following thimerosal containing DTaP vaccines in comparison to thimerosal free DTaP vaccines. Sep 29, 2011

Pubmed Data : Behav Brain Res. 2011 Sep 30 ;223(1):107-18. Epub 2011 Apr 28. PMID: 21549155
Article Published Date : Sep 29, 2011
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders, Neurodevelopmental Disorders
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus
Problem Substances : Thimerosal
[+]

Vitamin D treatment during pregnancy prevents autism-related phenotypes.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Autism. 2017 ;8:9. Epub 2017 Mar 7. PMID: 28316773
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Autism, Inflammation, Neurodevelopmental Disorders
[+]

Aspartame and L-glutamic acid work synergistically with food coloring agents to induce neurotoxicity.Mar 01, 2006

Pubmed Data : Toxicol Sci. 2006 Mar;90(1):178-87. Epub 2005 Dec 13. PMID: 16352620
Article Published Date : Mar 01, 2006
Study Type : In Vitro Study
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Excitotoxicity , Neurodevelopmental Disorders
Additional Keywords : Drug-Plant-Vitamin Synergies
Problem Substances : Aspartame, Brilliant Blue FCF, L-glutamic Acid, Quinoline Yellow
Adverse Pharmacological Actions : Neurotoxic
[+]

Astragaloside IV and ferulic acid synergistically promote neurite outgrowth through Nrf2 activation.Apr 08, 2019

Pubmed Data : Mech Ageing Dev. 2019 Apr 9. Epub 2019 Apr 9. PMID: 30978363
Article Published Date : Apr 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside, Ferulic acid
Diseases : Neurodevelopmental Disorders
Pharmacological Actions : Antioxidants, Neuritogenic, Nrf2 activation
Additional Keywords : Natural Substance Synergy
[+]

Culmination of the research that examines the effects of thimerosal in humans indicates that it is a poison at minute levels with a plethora of deleterious consequences.Apr 14, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Chim Acta. 2015 Apr 15 ;444:212-220. Epub 2015 Feb 21. PMID: 25708367
Article Published Date : Apr 14, 2015
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders, Neurodevelopmental Disorders, Tic Disorders
Problem Substances : Thimerosal
[+]

Early-life exposure to EDCs: role in childhood obesity and neurodevelopment.Nov 17, 2016

Pubmed Data : Nat Rev Endocrinol. 2016 Nov 18. Epub 2016 Nov 18. PMID: 27857130
Article Published Date : Nov 17, 2016
Study Type : Review
Additional Links
Diseases : Neurodevelopmental Disorders, Obesity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Phthalates, Triclosan
[+]

Effects of social isolation and loneliness in children with neurodevelopmental disabilities.Oct 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain Sci. 2020 Oct 28 ;10(11). Epub 2020 Oct 28. PMID: 33126519
Article Published Date : Oct 27, 2020
Study Type : Review
Additional Links
Diseases : Neurodevelopmental Disorders
Additional Keywords : Loneliness, Social Isolation
[+]

Folic acid supplementation in pregnancy may have beneficial effects on the neurodevelopment of children.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(11):e0165626. Epub 2016 Aug 22. PMID: 27875541
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Folic Acid
Diseases : Autism, Neurodevelopmental Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

Gestational exposure to common endocrine disrupting chemicals and their impact on neurodevelopment and behaviour.Nov 17, 2019

Pubmed Data : Annu Rev Physiol. 2019 Nov 18. Epub 2019 Nov 18. PMID: 31738670
Article Published Date : Nov 17, 2019
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Neurodevelopmental Disorders, Pesticide-Induced Toxicity: Organophosphates, Polychlorinated biphenyl toxicity , Prenatal Chemical Exposures
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Organophosphates, Polybrominated diphenylethers (PBDEs), Polychlorinated biphenyls (PCBs)
Adverse Pharmacological Actions : Neurotoxic
[+]

High susceptibility of neural stem cells to methylmercury toxicity: effects on cell survival and neuronal differentiation.Mar 31, 2006

Pubmed Data : J Neurochem. 2006 Apr ;97(1):69-78. Epub 2006 Mar 8. PMID: 16524380
Article Published Date : Mar 31, 2006
Study Type : In Vitro Study
Additional Links
Diseases : Neurodevelopmental Disorders
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Neural Stem Cell, Vaccine Adjuvant
Problem Substances : Thimerosal
[+]

Maternal acute and chronic inflammation in pregnancy is associated with common neurodevelopmental disorders.Jan 20, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Psychiatry. 2021 01 21 ;11(1):71. Epub 2021 Jan 21. PMID: 33479207
Article Published Date : Jan 20, 2021
Study Type : Review
Additional Links
Diseases : Fetal Origin of Adult Disease, Inflammation, Neurodevelopmental Disorders
Additional Keywords : Risk Factors
[+]

Melodic intonation therapy and related vocal techniques can improve expressive dysphasia and aid rehabilitation of neurologic disorders.Dec 15, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Tidsskr Nor Laegeforen. 2004 Dec 16 ;124(24):3229-30. PMID: 15608775
Article Published Date : Dec 15, 2004
Study Type : Review
Additional Links
Diseases : Dysphasia, Neurodevelopmental Disorders, Parkinson's Disease, Stroke: Attenuation/Recovery
Therapeutic Actions : Melodic Intonation Therapy
[+]

Microbial regulation of microRNA expression in the brain-gut axis.Oct 03, 2019

Pubmed Data : Curr Opin Pharmacol. 2019 Oct 4 ;48:120-126. Epub 2019 Oct 4. PMID: 31590111
Article Published Date : Oct 03, 2019
Study Type : Review
Additional Links
Diseases : Child Behavior Disorders, Cognitive Decline/Dysfunction, Neurodevelopmental Disorders
Additional Keywords : Gut-brain Axis
[+]

Postmortem analysis of Alzheimer brains reveals a loss in membrane cholesterol content, indicating that statin drugs may be contribute to neurodegenerative conditions. Apr 01, 2011

Pubmed Data : Neurol Sci. 2011 Apr ;32(2):195-201. Epub 2010 Oct 19. PMID: 20957505
Article Published Date : Apr 01, 2011
Study Type : Review
Additional Links
Diseases : Neurodevelopmental Disorders, Statin-Induced Pathologies
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]

Taurine can be directly used in clinical applications to improve brain development because it has no toxic effects on humans.Feb 22, 2016

Pubmed Data : Nutr Neurosci. 2016 Feb 23. Epub 2016 Feb 23. PMID: 26906683
Article Published Date : Feb 22, 2016
Study Type : Review
Additional Links
Substances : Taurine
Diseases : Neurodevelopmental Disorders
Pharmacological Actions : Neurogenesis, Neuroprotective Agents
[+]

The benefits of breastfeeding and associated risks of replacement with baby formulas.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rev Chil Pediatr. 2017 Feb ;88(1):7-14. PMID: 28288222
Article Published Date : Jan 31, 2017
Study Type : Review
Additional Links
Diseases : Attention Deficit Disorder, Neurodevelopmental Disorders, Sudden Infant Death Syndrome (SIDS)
Therapeutic Actions : Breastfeeding
Additional Keywords : Mortality, Risk Reduction
Problem Substances : Infant Formula
[+]

The collective works described here predominantly support the notion that gestational exposure to BPA should be regarded as a risk factor for neurodevelopmental disorders.Mar 06, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Mar 7 ;23(5). Epub 2022 Mar 7. PMID: 35270035
Article Published Date : Mar 06, 2022
Study Type : Review
Additional Links
Diseases : Anxiety, Bisphenol Toxicity, Learning disorders, Memory Disorders, Neurodevelopmental Disorders
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Neurotoxic
[+]

The contribution of the gut microbiome to neurodevelopment and neuropsychiatric disorders.Dec 31, 2018

Pubmed Data : Pediatr Res. 2019 Jan ;85(2):216-224. Epub 2018 Sep 25. PMID: 30283047
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders, Dysbiosis, Neurodevelopmental Disorders, Psychiatric Disorders
Additional Keywords : Gut-brain Axis
[+]

These nine studies suggest an increased risk of adverse neurodevelopmental outcomes following prenatal acetaminophen exposure.Apr 30, 2018

Pubmed Data : Horm Behav. 2018 May ;101:125-147. Epub 2018 Feb 3. PMID: 29341895
Article Published Date : Apr 30, 2018
Study Type : Review
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity , Attention Deficit Disorder with Hyperactivity, Autism Spectrum Disorders, Neurodevelopmental Disorders, Prenatal Chemical Exposures
Additional Keywords : Increased Risk
Problem Substances : Acetaminophen, Paracetamol
[+]

Thimerosal exposure is associated with adverse neurodevelopmental outcomes. Nov 02, 2016

Pubmed Data : Environ Res. 2016 Nov 3 ;152:280-293. Epub 2016 Aug 3. PMID: 27816865
Article Published Date : Nov 02, 2016
Study Type : Review
Additional Links
Diseases : Neurodevelopmental Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Thimerosal reduced SNAP-25 mRNA levels to 73% and 69% of the control levels. Sep 26, 2016

Pubmed Data : Toxicology. 2016 Sep 27. Epub 2016 Aug 27. PMID: 27693314
Article Published Date : Sep 26, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Neurodevelopmental Disorders
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

This review postulates that perturbations in the gut microbial-derived nutrient supply profoundly impacts upon normal brain development and function.Apr 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gut Microbes. 2014 May-Jun;5(3):369-80. Epub 2014 Mar 31. PMID: 24685620
Article Published Date : Apr 30, 2014
Study Type : Review
Additional Links
Diseases : Dysbiosis, Neurodevelopmental Disorders
Additional Keywords : Gut-brain Axis, Microbiota
[+]

This reviews the potential mechanisms by which the gut microbiota may regulate the brain-gut axis and influence behaviour.Mar 12, 2017

Pubmed Data : Eur Child Adolesc Psychiatry. 2017 Mar 13. Epub 2017 Mar 13. PMID: 28289903
Article Published Date : Mar 12, 2017
Study Type : Review
Additional Links
Diseases : Attention Deficit Hyperactivity Disorder, Dysbiosis, Neurodevelopmental Disorders
Additional Keywords : Gut-brain Axis, Microbiota
[+]

This study shows that inhibition of methionine synthase(MS) activity by ethanol, lead, mercury, aluminum and thimerosal suggesting that it may be an important target of neurodevelopmental toxins.Mar 31, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Psychiatry. 2004 Apr ;9(4):358-70. PMID: 14745455
Article Published Date : Mar 31, 2004
Study Type : In Vitro Study
Additional Links
Diseases : Attention Deficit Disorder, Autism Spectrum Disorders, Neurodevelopmental Disorders
Problem Substances : Aluminum, Ethanol, Lead, Thimerosal
Adverse Pharmacological Actions : Hypermethylation
[+]

Vitamin B12 regulates glial migration and synapse formation through isoform-specific control of PTP-3/LAR PRTP expression.Mar 23, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Rep. 2020 Mar 24 ;30(12):3981-3988.e3. PMID: 32209461
Article Published Date : Mar 23, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitamin B-12
Diseases : Neurodevelopmental Disorders, Vitamin B 12 Deficiency
Pharmacological Actions : Neuroprotective Agents

Copyright: pixologic / 123RF Stock Photo

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