Nicotine/Tobacco Toxicity

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56 Substances Researched for Nicotine/Tobacco Toxicity
NameACCKFocus
Curcumin1118Locked
Noni212Locked
Vitamin B-12312Locked
Vitamin B-12: Hydroxocobalamin211Locked
Vitamin E611Locked
Aloe Vera110Locked
Bee Propolis110Locked
Licorice110Locked
Pomegranate110Locked
Turmeric110Locked
Vitamin C69Locked
Garlic47Locked
Onion36Locked
Caffeic acid phenethyl ester15Locked
Sulforaphane35Locked
Crocin24Locked
EGCG (Epigallocatechin gallate)24Locked
Harmine24Locked
Melatonin34Locked
Spirulina24Locked
Royal Jelly23Locked
Achiote12Locked
Antioxidant formulas12Locked
Artichoke12Locked
Carotenoids12Locked
Cryptoxanthin12Locked
Cucurbitacin E 12Locked
Dates12Locked
Ellagic Acid12Locked
Fish Oil12Locked
Genistein12Locked
Green Tea12Locked
Lignans12Locked
Lotus 12Locked
Moringa oleifera12Locked
NAC (N-acetyl-L-cysteine)12Locked
Nettle12Locked
Nigella sativa (aka Black Seed)12Locked
Peach12Locked
Phenethyl isothiocyanate12Locked
Quercetin12Locked
Rosmarinic acid12Locked
Sage12Locked
Selenium12Locked
Spearmint12Locked
Theanine12Locked
Zeolite12Locked
Anthocyanins11Locked
Coenzyme Q1011Locked
Folic Acid 11Locked
Grape Seed Extract11Locked
Parthenolide11Locked
Proanthocyanidins11Locked
Rooibos11Locked
Tea11Locked
Vitamin E: alpha tocopherol11Locked
8 Problem Substances Researched for Nicotine/Tobacco Toxicity
NameACCKFocus
Electronic Cigarettes1950Locked
Nicotine1435Locked
Tobacco: Smoking211Locked
Tobacco110Locked
Lead12Locked
Benzo(a)pyrene11Locked
Cyanocobalamin 11Locked
Propylene Glycol11Locked
Related Topics

Nicotine/Tobacco Toxicity is a Sub of the following Topic

View the Evidence:
108 Abstracts with Nicotine/Tobacco Toxicity Research

[+]

Detoxification effects of aloe polysaccharide and propolis on the urinary excretion of metabolites in smokers.Jul 31, 2019

Pubmed Data : Food Chem Toxicol. 2019 Aug ;130:99-108. Epub 2019 May 18. PMID: 31112706
Article Published Date : Jul 31, 2019
Study Type : Human Study
Additional Links
Substances : Aloe Vera, Bee Propolis
Diseases : Lung Cancer, Nicotine/Tobacco Toxicity , Smoking
Pharmacological Actions : Anticarcinogenic Agents, Detoxifier
Additional Keywords : Polysaccharides
[+]

Electronic cigarettes increase endothelial progenitor cells in the blood of healthy volunteers.Jan 11, 2016

Pubmed Data : Atherosclerosis. 2016 12 ;255:179-185. Epub 2016 Sep 22. PMID: 27693003
Article Published Date : Jan 11, 2016
Study Type : Human Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity , Smoking
Additional Keywords : Risk Factors
Problem Substances : Electronic Cigarettes
[+]

Hydroxocobalamin is a cyanide antidote.Jan 01, 1993

Pubmed Data : J Toxicol Clin Toxicol. 1993;31(2):277-94. PMID: 8492341
Article Published Date : Jan 01, 1993
Study Type : Human Study
Additional Links
Substances : Vitamin B-12, Vitamin B-12: Hydroxocobalamin
Diseases : Cyanide Poisoning, Hypertension, Nicotine/Tobacco Toxicity , Smoking
[+]

Noni juice improves serum lipid profiles and other risk markers in cigarette smokers.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2012 ;2012:594657. Epub 2012 Oct 11. PMID: 23097636
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Noni
Diseases : C-Reactive Protein, Dyslipidemias, Nicotine/Tobacco Toxicity , Oxidative Stress, Smoking
Pharmacological Actions : Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Pomegranate and licorice drinks could increase the metabolism rate for nicotine.Sep 27, 2016

Pubmed Data : J Pharm Biomed Anal. 2016 Sep 28 ;132:60-65. Epub 2016 Aug 28. PMID: 27693954
Article Published Date : Sep 27, 2016
Study Type : Human Study
Additional Links
Substances : Licorice, Pomegranate
Diseases : Nicotine/Tobacco Toxicity , Smoking Cessation: Nicotine Addiction
[+]

Prenatal exposure to cigarette smoke and second-hand smoke affect infant cognitive development, especially language abilities.Dec 31, 2016

Pubmed Data : Matern Child Health J. 2017 04 ;21(4):734-744. PMID: 27465062
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity
[+]

Rapid brain nicotine uptake from electronic cigarettes.Oct 31, 2019

Pubmed Data : J Nucl Med. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31676729
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity , Smoking Cessation: Nicotine Addiction
Problem Substances : Electronic Cigarettes
[+]

Smoking cessation improves skin quality. Jan 01, 2010

Pubmed Data : Skinmed. 2010 Jan-Feb;8(1):23-9. PMID: 20839421
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Aging Skin, Nicotine/Tobacco Toxicity , Wrinkles, Aging Skin
Problem Substances : Tobacco: Smoking
[+]

The present study indicates that inhaled e-cigarette aerosol with nicotine has an acute impact on vascular and pulmonary function.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc Toxicol. 2019 Oct ;19(5):441-450. PMID: 30963443
Article Published Date : Sep 30, 2019
Study Type : Human Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

Tobacco consumption is associated with increased risk for ALS. Jan 15, 2000

Pubmed Data : Am J Epidemiol. 2000 Jan 15;151(2):156-63. PMID: 10645818
Article Published Date : Jan 15, 2000
Study Type : Human Study
Additional Links
Diseases : Amyotrophic Lateral Sclerosis, Nicotine/Tobacco Toxicity , Smoking
Problem Substances : Nicotine, Tobacco
Adverse Pharmacological Actions : Neurotoxic
[+]

Tumeric has an anti-mutagenic activity on urinary mutagens in smokers.Mar 01, 1992

Pubmed Data : Mutagenesis. 1992 Mar;7(2):107-9. PMID: 1579064
Article Published Date : Mar 01, 1992
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Nicotine/Tobacco Toxicity , Smoking
Pharmacological Actions : Antimutagenic Agents
Additional Keywords : Plant Extracts
[+]

Caffeic acid phenethyl ester reduces the adverse effects of nicotine on the endometrium.Aug 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Med Sci. 2023 Sep ;48(5):493-500. PMID: 37786469
Article Published Date : Aug 31, 2023
Study Type : Human In Vitro
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Nicotine/Tobacco Toxicity
[+]

Tobacco smoke and nicotine suppress expression of activating signaling molecules in human dendritic cells.Dec 14, 2018

Pubmed Data : Toxicol Lett. 2018 Dec 15 ;299:40-46. Epub 2018 Sep 15. PMID: 30227238
Article Published Date : Dec 14, 2018
Study Type : Human In Vitro
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Problem Substances : Nicotine
Adverse Pharmacological Actions : Immunosuppressive
[+]

A diet rich in vitamin C and quercetin could prevent nicotine-induced toxicity.Nov 30, 2016

Pubmed Data : Arh Hig Rada Toksikol. 2016 Dec 1 ;67(4):304-310. PMID: 28033106
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Quercetin, Vitamin C
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

"Chronic nicotine toxicity is prevented by aqueous garlic extract."Jun 01, 2005

Pubmed Data : Plant Foods Hum Nutr. 2005 Jun ;60(2):77-86. PMID: 16021835
Article Published Date : Jun 01, 2005
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Additional Keywords : Plant Extracts
Problem Substances : Nicotine
Adverse Pharmacological Actions : Oxidant
[+]

"Garlic and vitamin E provides antioxidant defence in tissues of female rats treated with nicotine."Jan 01, 2011

Pubmed Data : Niger J Physiol Sci. 2011 ;26(1):103-7. Epub 2011 Nov 23. PMID: 22314996
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Garlic, Vitamin E
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

A hydro-alcoholic extract of Nettle could increase the quality of spermatozoa and inhibits nicotine-induced effects on sperm parameters.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Reprod Med. 2014 Jun ;12(6):401-8. PMID: 25071848
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Nettle
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Cytoprotective, Spermatogenic
Additional Keywords : Plant Extracts
[+]

A low-dose nicotine exposure at 0.6 mg/kg caused detrimental effects on sperm characteristics and induced oxidative stress in the testes and prostate.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Malays J Med Sci. 2017 Dec ;24(6):50-57. Epub 2017 Dec 29. PMID: 29379386
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress
[+]

Annatto supplementation protected against embryonic DNA damages.Jan 31, 2018

Pubmed Data : Int J Vitam Nutr Res. 2018 Feb ;88(1-2):16-26. Epub 2019 Mar 20. PMID: 30907699
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Achiote, Carotenoids, Vitamin E
Diseases : DNA damage, Nicotine/Tobacco Toxicity , Prenatal Chemical Exposures
Pharmacological Actions : Genoprotective
Additional Keywords : Plant Extracts
[+]

Chronic exposure to e-cig aerosols during early development causes vascular dysfunction and offspring growth deficits.Jan 06, 2019

Pubmed Data : Transl Res. 2019 Jan 7. Epub 2019 Jan 7. PMID: 30653941
Article Published Date : Jan 06, 2019
Study Type : Animal Study
Additional Links
Diseases : Fetal Origin of Adult Disease, Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

Crocin improves nicotine-induced adverse effects on reproductive parameters in male mice.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Fertil Steril. 2016 Apr-Jun;10(1):71-8. Epub 2016 Apr 5. PMID: 27123203
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Cytoprotective, Fertility Agents: Male
[+]

Cucurbitacin E ameliorates airway remodelling by inhibiting nerve growth factor expression in nicotine-treated bronchial epithelial cells.Jun 30, 2022

Pubmed Data : Basic Clin Pharmacol Toxicol. 2022 Jul ;131(1):34-44. Epub 2022 May 28. PMID: 35560511
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Cucurbitacin E
Diseases : Inflammation, Nicotine/Tobacco Toxicity
Pharmacological Actions : MicroRNA modulator, Neuritogenic
[+]

Curcumin ameliorates oxidative stress during nicotine-induced lung toxicity in rats.Jul 01, 2004

Pubmed Data : Ital J Biochem. 2004 Jul;53(2):82-6. PMID: 15646012
Article Published Date : Jul 01, 2004
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Curcumin could be useful to protect the liver from nicotine toxicity.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2016 Apr ;6(2):176-83. Epub 2015 Jan 31. PMID: 27114942
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Curcumin has a protective effect against nicotine-induced genotoxicity on rat liver. Jul 07, 2008

Pubmed Data : Eur J Pharmacol. 2008 Jul 7;588(2-3):151-7. Epub 2008 Apr 15. PMID: 18508046
Article Published Date : Jul 07, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemically-Induced Liver Damage, DNA damage, Nicotine/Tobacco Toxicity
Pharmacological Actions : Hepatoprotective
[+]

Curcumin protects against cigarette smoke and ethanol-induced lipid alterations in rat lung and liver.Jun 01, 2009

Pubmed Data : J Appl Microbiol. 2009 Jun;106(6):2086-95. Epub 2009 Mar 9. PMID: 16691314
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Alcohol Toxicity , Chemically-Induced Liver Damage, Lung Damage, Nicotine/Tobacco Toxicity , Oxidative Stress, Smoking
Pharmacological Actions : Hepatoprotective
[+]

Curcumin protects against lipid peroxidation and oxidative stress during nicotine-induced toxicity. Jan 01, 2004

Pubmed Data : Toxicol Mech Methods. 2004;14(6):339-43. PMID: 20021100
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Lipid Peroxidation, Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants
[+]

Curcumin protects against nicotine-induced lung toxicity by modulating the extent of lipid peroxidation and augmenting antioxidant defense system.Sep 01, 2004

Pubmed Data : Pol J Pharmacol. 2004 Sep-Oct;56(5):581-6. PMID: 15591646
Article Published Date : Sep 01, 2004
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Lipid Peroxidation, Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Effect of phoenix dactyliferia (date palm) pit powder on nicotine induced spermatotoxicty in adult albino mice.Dec 31, 2014

Pubmed Data : J Pak Med Assoc. 2015 Jan ;65(1):43-8. PMID: 25831673
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Dates
Diseases : DNA damage, Nicotine/Tobacco Toxicity , Smoking, Sperm Quality: Low
Pharmacological Actions : Genoprotective
Additional Keywords : Plant Extracts
Problem Substances : Nicotine
[+]

EGCG can be developed into a potential agent for the prevention and treatment of smoking‑associated NSCLC.May 31, 2015

Pubmed Data : Oncol Rep. 2015 Jun ;33(6):2972-80. Epub 2015 Mar 31. PMID: 25845434
Article Published Date : May 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Carcinoma: Small Cell Lung, Nicotine/Tobacco Toxicity
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Hypoxia-inducible factor-1 (HIF-1) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Ellagic acid played a protective role against nicotine-induced nephrotoxicity and oxidative stress.Dec 31, 2015

Pubmed Data : Biotech Histochem. 2016 ;91(2):108-15. Epub 2015 Nov 3. PMID: 26529089
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Lipid Peroxidation, Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Renoprotective
[+]

Epigallocatechin gallate ameliorates nicotine withdrawal conditions-induced somatic and affective behavior changes.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Neurol. 2023 ;2023:5581893. Epub 2023 Jun 13. PMID: 37346971
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : MicroRNA modulator
[+]

Fish oil might help prevent the development of abdominal aortic aneurysms.Jul 31, 2017

Pubmed Data : Food Funct. 2017 Aug 1 ;8(8):2829-2835. Epub 2017 Jul 20. PMID: 28725903
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fish Oil
Diseases : Aneurysm: Aortic, Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Matrix Metalloproteinase-12 (MMP-12) Inhibitor
[+]

Garlic and onion protect against nicotine-induced lipid peroxidation. Oct 01, 1999

Pubmed Data : Vet Hum Toxicol. 1999 Oct;41(5):316-9. PMID: 10509436
Article Published Date : Oct 01, 1999
Study Type : Animal Study
Additional Links
Substances : Garlic, Onion
Diseases : Nicotine/Tobacco Toxicity , Smoking, Tobacco Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Genistein improve nicotine toxicity on male mice pancreas.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Cell Biol. 2019 Jun ;52(2):183-190. Epub 2019 Jun 30. PMID: 31338235
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Pancreato Protective Agents
[+]

Harmine shows therapeutic activity on nicotine-induced liver failure in mice.May 02, 2019

Pubmed Data : Histol Histopathol. 2019 May 3:18122. Epub 2019 May 3. PMID: 31049922
Article Published Date : May 02, 2019
Study Type : Animal Study
Additional Links
Substances : Harmine
Diseases : Chemically-Induced Liver Damage, Nicotine/Tobacco Toxicity
Pharmacological Actions : Hepatoprotective
[+]

inhalation of e-cig vapor causes airway mucociliary dysfunction in vitro and in vivo.Jun 06, 2019

Pubmed Data : Am J Respir Crit Care Med. 2019 Jun 7. Epub 2019 Jun 7. PMID: 31170808
Article Published Date : Jun 06, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes, Nicotine
[+]

It seems that harmine administration improved kidney injury induced by nicotine.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Prev Med. 2019 ;10:97. Epub 2019 Jun 7. PMID: 31360344
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Harmine
Diseases : Kidney Damage: Chemically-Induced, Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Renoprotective
[+]

L-theanine attenuates nicotine reward and withdrawal signs.Jun 10, 2023

Pubmed Data : Neurosci Lett. 2023 Jun 11 ;807:137279. Epub 2023 Apr 25. PMID: 37105354
Article Published Date : Jun 10, 2023
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Anxiety Agents
[+]

M. spicata compounds have important antioxidant potential and protected liver and erythrocytes against nicotine-induced damage.Dec 31, 2017

Pubmed Data : Appl Physiol Nutr Metab. 2018 Jan ;43(1):77-83. Epub 2017 Sep 11. PMID: 28892646
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Spearmint
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Melatonin protects against nicotine-induced myocardial injry in newborn rats whose mothers received nicotine. Aug 01, 2008

Pubmed Data : Anadolu Kardiyol Derg. 2008 Aug;8(4):243-8. PMID: 18676298
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Nicotine/Tobacco Toxicity
[+]

Moringa oleifera could prevent nicotine-induced cerebellar injury Jan 03, 2018

Pubmed Data : Pathophysiology. 2018 Jan 4. Epub 2018 Jan 4. PMID: 29307662
Article Published Date : Jan 03, 2018
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Neuroprotective Agents
[+]

Nanozeolites and artichoke leaf extract has the synergetic effect on increasing the urinary excretion of nicotine.Nov 28, 2012

Pubmed Data : Arzneimittelforschung. 2012 Nov 29. Epub 2012 Nov 29. PMID: 23196970
Article Published Date : Nov 28, 2012
Study Type : Animal Study
Additional Links
Substances : Artichoke, Zeolite
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Detoxifier
Additional Keywords : Natural Substance Synergy
Problem Substances : Nicotine
[+]

Nephroprotective and antioxidant effect of green tea against nicotine-induced nephrotoxicity Feb 24, 2019

Pubmed Data : Appl Physiol Nutr Metab. 2019 Feb 25. Epub 2019 Feb 25. PMID: 30802143
Article Published Date : Feb 24, 2019
Study Type : Animal Study
Additional Links
Substances : Green Tea
Diseases : Kidney Damage: Chemically-Induced, Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants, Renoprotective
Problem Substances : Nicotine
[+]

Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5.Dec 31, 2017

Pubmed Data : Arch Biochem Biophys. 2018 11 1 ;657:65-73. Epub 2018 Sep 15. PMID: 30222954
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Alcohol Toxicity , Alcoholic Liver Disease, Nicotine/Tobacco Toxicity , Oxidative Stress
Additional Keywords : Increased Risk
Problem Substances : Nicotine
[+]

Nicotine impairs T cell responsiveness in a rat model. Sep 01, 2002

Pubmed Data : J Pharmacol Exp Ther. 2002 Sep;302(3):935-9. PMID: 12183649
Article Published Date : Sep 01, 2002
Study Type : Animal Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity , Smoking
Pharmacological Actions : Antiproliferative
[+]

Nigella sativa and onion extract attenuate the pathological effect of nicotine in the lung.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Folia Morphol (Warsz). 2019 ;78(3):554-563. Epub 2018 Dec 21. PMID: 30575005
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed), Onion
Diseases : Lung Injury: Smoke-Induced, Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Noni (Morinda citrifolia) reduces cancer risk in current smokers by decreasing aromatic DNA adducts.Jan 01, 2009

Pubmed Data : Nutr Cancer. 2009;61(5):634-9. PMID: 19838937
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : DNA damage, Nicotine/Tobacco Toxicity , Smoking
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Risk Reduction
[+]

Nuciferine not only inhibited the growth of NSCLC cells, but also remarkably alleviated the injury induced by nicotine in liver function.May 12, 2015

Pubmed Data : J Ethnopharmacol. 2015 May 13 ;165:83-93. Epub 2015 Feb 16. PMID: 25698245
Article Published Date : May 12, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lotus
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer, Nicotine/Tobacco Toxicity
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 Ratio: Decrease, Hepatoprotective, Wnt/β-catenin pathway down-regulation
[+]

Onion compares favorably to vitamin E in ameliorating the oxidative effects of nicotine in rats. Jul 27, 2000

Pubmed Data : Toxicol Lett. 2000 Jul 27;116(1-2):61-8. PMID: 10906423
Article Published Date : Jul 27, 2000
Study Type : Animal Study
Additional Links
Substances : Onion, Vitamin E
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress, Smoking
Pharmacological Actions : Antioxidants
[+]

Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.Sep 15, 2005

Pubmed Data : Cancer Res. 2005 Sep 15;65(18):8548-57. PMID: 16166336
Article Published Date : Sep 15, 2005
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine), Phenethyl isothiocyanate, Sulforaphane
Diseases : Lung Cancer, Nicotine/Tobacco Toxicity , Smoking
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Isothiocyanates
[+]

Pulmonary immune response regulation, genotoxicity, and metabolic reprogramming by menthol- and tobacco-flavored e-cigarette exposures.May 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Sci. 2023 May 31 ;193(2):146-165. PMID: 37052522
Article Published Date : May 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

Renoprotective effect of Spirulina platensis extract against nicotine-induced oxidative stress-mediated inflammation.Sep 30, 2018

Pubmed Data : Phytomedicine. 2018 Oct 1 ;49:106-110. Epub 2018 Jul 19. PMID: 30217256
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Inflammation, Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

Rosmarinic acid inhibits nicotine-induced C-reactive protein generation.Aug 25, 2018

Pubmed Data : J Cell Physiol. 2018 Aug 26. Epub 2018 Aug 26. PMID: 30146678
Article Published Date : Aug 25, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Atherosclerosis, C-Reactive Protein, Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Royal-jelly-based apitherapy can attenuate damages to male reproductive parameter following nicotine administration.Mar 10, 2022

Pubmed Data : Animal Model Exp Med. 2022 Mar 11. Epub 2022 Mar 11. PMID: 35274495
Article Published Date : Mar 10, 2022
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation
[+]

Salvia officinalis methanolic extract reduces lead and nicotine-induced sperm quality degeneration.Jun 30, 2023

Pubmed Data : Chem Biodivers. 2023 Jul ;20(7):e202300115. Epub 2023 Jun 15. PMID: 37236909
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Nicotine/Tobacco Toxicity , Sperm Quality: Low
Pharmacological Actions : Fertility Agents: Male
Additional Keywords : Plant Extracts
Problem Substances : Lead
[+]

Selenium reduces the adverse effects of cigarette smoke exposure to the brain and lungs of rats. Mar 01, 2009

Pubmed Data : Pharmacol Res. 2009 Mar;59(3):194-201. Epub 2008 Nov 28. PMID: 19095064
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Nicotine/Tobacco Toxicity , Tobacco Toxicity
Pharmacological Actions : Antioxidants
[+]

Sesame extract may be effective in preventing abdominal aortic aneurysm development.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Oleo Sci. 2019 ;68(1):79-85. PMID: 30606956
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Lignans
Diseases : Aortic Aneurysm, Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants, Matrix Metalloproteinase-12 (MMP-12) Inhibitor
Additional Keywords : Plant Extracts
[+]

Several genes associated with bone metabolism and genes in the Hedgehog and Notch signalling pathways were downregulated significantly by nicotine.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 Jun ;17(6):8269-8281. Epub 2018 Apr 13. PMID: 29658611
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Additional Keywords : Gene Expression
[+]

Short-term exposure to e-cigarette aerosol promotes neutrophil recruitment and enhances neutrophil-platelet aggregation in pulmonary microvasculature.Apr 17, 2023

Pubmed Data : J Toxicol Environ Health A. 2023 Apr 18 ;86(8):246-262. Epub 2023 Mar 1. PMID: 36859793
Article Published Date : Apr 17, 2023
Study Type : Animal Study
Additional Links
Diseases : Lung Inflammation, Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

Spirulina platensis-lipopolysaccharides mitigate the oxidative stress and impairment of rats' brain induced by nicotine.Apr 24, 2020

Pubmed Data : Arch Biochem Biophys. 2020 Apr 25:108382. Epub 2020 Apr 25. PMID: 32343976
Article Published Date : Apr 24, 2020
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Sulforaphane inhibits the acquisition of tobacco smoke-induced lung cancer stem cell-like properties.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Theranostics. 2019 ;9(16):4827-4840. Epub 2019 Jul 9. PMID: 31367260
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Lung Cancer, Nicotine/Tobacco Toxicity
Pharmacological Actions : Chemopreventive
Additional Keywords : Cancer Stem Cells
[+]

Supplementation with Vitamin C and E improve lung repair aftery emphysema induced by long-term cigarette smoke exposure in mice. Sep 01, 2008

Pubmed Data : J Nutr Biochem. 2008 Sep;19(9):604-11. Epub 2007 Dec 21. PMID: 18155509
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Antioxidant formulas, Vitamin C, Vitamin E
Diseases : Emphysema: Pulmonary, Nicotine/Tobacco Toxicity , Smoking: Pulmonary
Additional Keywords : Smoking
[+]

The present study indicates that BCX is a preventive agent against emphysema and lung cancer with SIRT1 as a potential target.Mar 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Prev Res (Phila). 2013 Apr ;6(4):309-20. Epub 2012 Dec 28. PMID: 23275008
Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Substances : Cryptoxanthin
Diseases : Lung Cancer, Nicotine/Tobacco Toxicity , Pulmonary Emphysema
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, SIRT1 Activator
Additional Keywords : Gene Expression Regulation, Risk Reduction
[+]

The study demonstrated that curcumin was a potent protective compound against the nicotine-induced stress.Nov 30, 2015

Pubmed Data : Mol Biol Rep. 2015 Dec ;42(12):1623-37. Epub 2015 Nov 11. PMID: 26559197
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Immunomodulatory
[+]

These results demonstrate that crocin can mitigate nicotine‑induced neurodegeneration by reducing oxidative stress.Mar 27, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Neurobiol Exp (Wars). 2024 Mar 28 ;84(1):59-69. Epub 2024 Mar 28. PMID: 38587323
Article Published Date : Mar 27, 2024
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

These results indicate that chronic paternal nicotine exposure can impact the behavior of offspring.Jul 31, 2019

Pubmed Data : Neurotoxicol Teratol. 2019 Jul - Aug;74:106808. Epub 2019 May 16. PMID: 31103693
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity , Prenatal Chemical Exposures
Problem Substances : Nicotine
Adverse Pharmacological Actions : Neurotoxic
[+]

This study demonstrates a sex-dependent effect of nicotine on gut microbiome community composition, functional bacterial genes, and the fecal metabolome.Jan 17, 2017

Pubmed Data : Chem Res Toxicol. 2017 12 18 ;30(12):2110-2119. Epub 2017 Nov 16. PMID: 29035044
Article Published Date : Jan 17, 2017
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Nicotine/Tobacco Toxicity , Oxidative Stress
Additional Keywords : Microbiota
[+]

Vitamin C mitigates the genotoxic properties of nicotine in mice. Feb 06, 2012

Pubmed Data : Mutat Res. 2012 Feb 6. Epub 2012 Feb 6. PMID: 22331007
Article Published Date : Feb 06, 2012
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Genoprotective
Problem Substances : Nicotine
Adverse Pharmacological Actions : Genotoxic
[+]

Vitamin E attenuates nicotine and noise-induced reproductive impairment in male albino Wistar rats.May 27, 2018

Pubmed Data : Andrologia. 2018 May 28:e13050. Epub 2018 May 28. PMID: 29806220
Article Published Date : May 27, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin E
Diseases : Infertility: Male, Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants
[+]

White-fleshed peaches may increase the metabolism of toxic components in tobacco smoke in smokers and protect normal tissues against nicotine toxicity.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer Prev. 2017 Mar ;22(1):22-32. Epub 2017 Mar 30. PMID: 28382283
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Peach
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Cytoprotective
[+]

A review of e-cigarettes and cancer risk.Oct 15, 2019

Pubmed Data : Cancer Prev Res (Phila). 2019 Oct 16. Epub 2019 Oct 16. PMID: 31619443
Article Published Date : Oct 15, 2019
Study Type : Review
Additional Links
Diseases : Cancers: All, Nicotine/Tobacco Toxicity
Additional Keywords : Risk Factors
Problem Substances : Electronic Cigarettes
[+]

Aerosols of e-liquids consisting only of PG/VG solvents can cause severe cytotoxicity depending on the concentration of propylene glycol.Feb 04, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Respir Res. 2024 Feb 5 ;25(1):75. Epub 2024 Feb 5. PMID: 38317149
Article Published Date : Feb 04, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Inflammation, Nicotine/Tobacco Toxicity , Oxidative Stress
Problem Substances : Electronic Cigarettes, Propylene Glycol
[+]

Ascorbic acid mitigates the deleterious effects of nicotine on tendon stem cells.Sep 04, 2019

Pubmed Data : Connect Tissue Res. 2019 Sep 5:1-11. Epub 2019 Sep 5. PMID: 31488012
Article Published Date : Sep 04, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Apoptotic, Cytoprotective
[+]

Coenzyme Q10 strongly inhibits nicotine-mediated production of reactive oxygen species and consequent apoptosis.Oct 21, 2016

Pubmed Data : Apoptosis. 2016 Oct 22. Epub 2016 Oct 22. PMID: 27770269
Article Published Date : Oct 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Coenzyme Q10
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Problem Substances : Electronic Cigarettes
[+]

Curcumin has anti-mutagenic properties against environmental mutagens.Jul 01, 1987

Pubmed Data : Food Chem Toxicol. 1987 Jul;25(7):545-7. PMID: 3623345
Article Published Date : Jul 01, 1987
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Benzo[a]pyrene-induced Toxicity , Nicotine/Tobacco Toxicity
Pharmacological Actions : Detoxifier
Additional Keywords : Plant Extracts
[+]

Curcumin has chemopreventive properties in nicotine-induced proliferation and angiogenesis in llung cancer cells.Jan 01, 2010

Pubmed Data : Mol Cancer. 2010;9:220. Epub 2010 Aug 20. PMID: 20727180
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Lung Cancer, Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Angiogenic, Antiproliferative , Chemopreventive, Cyclooxygenase 2 Inhibitors, Tumor Suppressor Protein p53 Upregulation
[+]

Curcumin inhibits nicotine-induced toxicity. Jan 01, 2004

Pubmed Data : J Med Food. 2004;7(4):467-71. PMID: 15671691
Article Published Date : Jan 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Cyanocobalamin--a case for withdrawal: discussion paper.Nov 01, 1992

Pubmed Data : J R Soc Med. 1992 Nov;85(11):686-7. PMID: 1474554
Article Published Date : Nov 01, 1992
Study Type : Commentary
Additional Links
Substances : Vitamin B-12, Vitamin B-12: Hydroxocobalamin
Diseases : Cyanide Poisoning, Nicotine/Tobacco Toxicity , Smoking, Tobacco Toxicity , Vitamin B 12 Deficiency
Additional Keywords : Vitamin B12 Differences
Problem Substances : Cyanocobalamin
[+]

E-cigarette aerosol condensate leads to impaired coronary endothelial cell health and restricted angiogenesis.Mar 27, 2023

Pubmed Data : Int J Mol Sci. 2023 Mar 28 ;24(7). Epub 2023 Mar 28. PMID: 37047355
Article Published Date : Mar 27, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Cardiovascular Diseases, Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

Exposure to nicotine might negatively impact the apoptotic potential of chemotherapeutics.Feb 29, 2012

Pubmed Data : Med Oncol. 2012 Mar ;29(1):364-73. Epub 2011 Jan 26. PMID: 21267677
Article Published Date : Feb 29, 2012
Study Type : In Vitro Study
Additional Links
Diseases : Cancers: Drug Resistant, Lung Cancer, Nicotine/Tobacco Toxicity
Problem Substances : Nicotine
[+]

Financial ties and conflicts of interest between pharmaceutical and tobacco companies.Aug 13, 2002

Pubmed Data : JAMA. 2002 Aug 14 ;288(6):738-44. PMID: 12169078
Article Published Date : Aug 13, 2002
Study Type : Review
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Additional Keywords : Conflict Of Interest (COI)
[+]

Flavored E-cigarette product aerosols induce transformation of human bronchial epithelial cells.Apr 30, 2023

Pubmed Data : Lung Cancer. 2023 May ;179:107180. Epub 2023 Mar 22. PMID: 36989612
Article Published Date : Apr 30, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Lung Cancer, Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin.Jan 15, 2018

Pubmed Data : J Pineal Res. 2018 Jan 16. Epub 2018 Jan 16. PMID: 29338098
Article Published Date : Jan 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Breast Cancer, Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-metastatic
Additional Keywords : Anti-metastatic, Breast Cancer, melatonin, Nicotine/Tobacco Toxicity
[+]

Insights into the mechanisms of action of proanthocyanidins and anthocyanins in the treatment of nicotine-induced non-small cell lung cancer.Jul 17, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Jul 18 ;23(14). Epub 2022 Jul 18. PMID: 35887251
Article Published Date : Jul 17, 2022
Study Type : Review
Additional Links
Substances : Anthocyanins, Proanthocyanidins
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer, Nicotine/Tobacco Toxicity
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antiproliferative , Apoptotic
[+]

Interplay between proteasome function and inflammatory responses in e-cig vapor condensate-challenged lung epithelial cells.Jul 31, 2023

Pubmed Data : Arch Toxicol. 2023 Aug ;97(8):2193-2208. Epub 2023 Jun 22. PMID: 37344694
Article Published Date : Jul 31, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Inflammation, Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

Long term effects of cigarette smoke extract or nicotine on nerve growth factor and its receptors in a bronchial epithelial cell line.Nov 30, 2018

Pubmed Data : Toxicol In Vitro. 2018 Dec ;53:29-36. Epub 2018 Aug 1. PMID: 30076938
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

Melatonin attenuates nicotine-induced autophagy and neurological changes by decreasing the production of reactive oxygen species.Nov 25, 2019

Pubmed Data : Int J Neurosci. 2019 Nov 26:1-7. Epub 2019 Nov 26. PMID: 31721620
Article Published Date : Nov 25, 2019
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Neuroprotective Agents
[+]

Menthol flavoring in e-cigarette condensate causes pulmonary dysfunction and cytotoxicity.Feb 28, 2023

Pubmed Data : Am J Physiol Lung Cell Mol Physiol. 2023 Mar 1 ;324(3):L345-L357. Epub 2023 Jan 24. PMID: 36692165
Article Published Date : Feb 28, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

Nicotine could achieve α7 nAChR-mediated proliferation and anti-apoptotic effects in cisplatin treated cells. Feb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Rep. 2014 Mar ;31(3):1480-8. Epub 2013 Dec 31. PMID: 24399025
Article Published Date : Feb 28, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Cancers: Drug Resistant, Lymphoma, Nicotine/Tobacco Toxicity
Problem Substances : Nicotine
[+]

Nicotine increases the resistance of lung cancer cells to cisplatin through enhancing Bcl-2 stability.Apr 01, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Cancer. 2014 Apr 2 ;110(7):1785-92. Epub 2014 Feb 18. PMID: 24548862
Article Published Date : Apr 01, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Cancers: Drug Resistant, Lung Cancer, Nicotine/Tobacco Toxicity
Problem Substances : Nicotine
[+]

Nicotine induces aberrant hypermethylation of tumor suppressor genes in pancreatic epithelial ductal cells.May 22, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 May 23 ;499(4):934-940. Epub 2018 Apr 11. PMID: 29626481
Article Published Date : May 22, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity , Pancreatic Cancer
[+]

Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations.May 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Respir J. 2023 Jun ;61(6). Epub 2023 Jun 22. PMID: 37105573
Article Published Date : May 31, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Lung Inflammation, Nicotine/Tobacco Toxicity
Additional Keywords : Plant Extracts
Problem Substances : Electronic Cigarettes
[+]

Nicotine upregulates FGFR3 and RB1 expression and promotes non-small cell lung cancer cell proliferation.Apr 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 May ;101:656-662. Epub 2018 Mar 22. PMID: 29518612
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Carcinoma: Non-Small-Cell Lung, Nicotine/Tobacco Toxicity
Additional Keywords : Increased Risk
[+]

Nicotine-induced oxidative stress contributes to EMT and stemness during neoplastic transformation in human kidney epithelial cells.Jun 30, 2019

Pubmed Data : Toxicol Appl Pharmacol. 2019 Jul 1 ;374:65-76. Epub 2019 Apr 29. PMID: 31047982
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Kidney Cancer, Kidney Damage: Chemically-Induced, Nicotine/Tobacco Toxicity
Problem Substances : Nicotine
[+]

Orally administered nicotine effects on rat urinary bladder proliferation and carcinogenesis.Mar 31, 2018

Pubmed Data : Toxicology. 2018 Apr 1 ;398-399:31-40. Epub 2018 Mar 6. PMID: 29501575
Article Published Date : Mar 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Bladder Cancer, Nicotine/Tobacco Toxicity
[+]

Parthenolide is a promising natural product for inhibiting and treating nicotine-associated lung cancer. Oct 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:1488-1495. Epub 2018 Sep 4. PMID: 30257366
Article Published Date : Oct 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Parthenolide
Diseases : Lung Cancer, Nicotine/Tobacco Toxicity
Pharmacological Actions : Apoptotic, Tumor Suppressor Protein p53 Upregulation, Vascular Endothelial Growth Factor Inhibitors
[+]

Rooibos protects against nicotine induced vascular injury and oxidative stress.Feb 06, 2020

Pubmed Data : Cardiovasc J Afr. 2020 Feb 7 ;31:1-10. Epub 2020 Feb 7. PMID: 32031565
Article Published Date : Feb 06, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Endothelial Dysfunction, Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants
[+]

Royal jelly protects male mice against nicotine-induced reproductive failure.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet Res Forum. 2018 ;9(3):231-238. Epub 2018 Sep 15. PMID: 30357078
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Royal Jelly
Diseases : Infertility: Male, Nicotine/Tobacco Toxicity , Testicular Injury: Nicotine-Induced
Pharmacological Actions : Antioxidants, Fertility Agents: Male
[+]

Six dietary constituents inhibit nicotine-DNA adduct formation. Jul 01, 2003

Pubmed Data : Food Chem Toxicol. 2003 Jul;41(7):1045-50. PMID: 12804663
Article Published Date : Jul 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Garlic, Grape Seed Extract, Tea, Vitamin C, Vitamin E
Diseases : DNA damage, Nicotine/Tobacco Toxicity
Pharmacological Actions : Genoprotective
Additional Keywords : Plant Extracts
[+]

Targeting mitochondria with folic acid and vitamin B12 ameliorates nicotine mediated islet cell dysfunction.Aug 31, 2018

Pubmed Data : Environ Toxicol. 2018 Sep ;33(9):988-1000. Epub 2018 Jul 4. PMID: 29972271
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid , Vitamin B-12
Diseases : Mitochondrial Dysfunction , Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants
[+]

The current study provides valuable evidence for developing sulforaphane as a new anti-invasion strategy for human gastric cancer therapy.May 04, 2022

Pubmed Data : Int J Mol Sci. 2022 May 5 ;23(9). Epub 2022 May 5. PMID: 35563563
Article Published Date : May 04, 2022
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Gastric Cancer, Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor
[+]

There are 4000 toxic substances and 600 additives used in tobacco. Jan 01, 2007

Pubmed Data : Pneumologia. 2007 Jan-Mar;56(1):41, 43-6. PMID: 17491209
Article Published Date : Jan 01, 2007
Study Type : Review
Additional Links
Diseases : Inflammation, Lung Cancer, Nicotine/Tobacco Toxicity , Smoking
Problem Substances : Tobacco: Smoking
[+]

These results show that the nicotine content of electronic cigarettes may have adverse pulmonary and systemic effects.Oct 24, 2018

Pubmed Data : Am J Physiol Lung Cell Mol Physiol. 2018 Oct 25. Epub 2018 Oct 25. PMID: 30358437
Article Published Date : Oct 24, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Problem Substances : Electronic Cigarettes
[+]

This is first report demonstrating that e-cigarettes can potentiate the genotoxic effects of a tobacco smoke carcinogen.Jan 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2019 07 11 ;16(14). Epub 2019 Jul 11. PMID: 31373329
Article Published Date : Jan 10, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Benzo[a]pyrene-induced Toxicity , Nicotine/Tobacco Toxicity , Smoking
Additional Keywords : Increased Risk, Synergistic Toxicity
Problem Substances : Benzo(a)pyrene, Electronic Cigarettes
[+]

Toxicity of electronic cigarettes: A general review of the origins, health hazards, and toxicity mechanisms.Jun 09, 2021

Pubmed Data : Sci Total Environ. 2021 Jun 10 ;772:145475. Epub 2021 Jan 30. PMID: 33770885
Article Published Date : Jun 09, 2021
Study Type : Review
Additional Links
Diseases : Nicotine/Tobacco Toxicity , Smoking
Problem Substances : Electronic Cigarettes
[+]

Vitamin C and especially vitamin E may be useful in the repair and regeneration of oral hard and soft tissues in smokers.Oct 11, 2017

Pubmed Data : Eur J Oral Sci. 2017 Oct 12. Epub 2017 Oct 12. PMID: 29024129
Article Published Date : Oct 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: alpha tocopherol
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Regenerative
[+]

Vitamin C inhibits glycidamide-induced genotoxicity and apoptosis in sertoli cells. Jul 06, 2020

Pubmed Data : J Biochem Mol Toxicol. 2020 Jul 7:e22545. Epub 2020 Jul 7. PMID: 32632975
Article Published Date : Jul 06, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Apoptotic, Genoprotective

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