Nonalcoholic fatty liver disease (NAFLD)

Name	AC	CK
Vitamin D	15	92
Curcumin	18	86
Vitamin E	9	83
Probiotics	14	64
Silymarin	7	56
Coffee	4	43
Omega-3 Fatty Acids	7	37
Yoghurt	4	32
Berberine	17	31
Polyunsaturated Fatty Acids (PUFAs)	2	30
Ginseng (Korean)	5	25
Hydroxytyrosol	5	25
Vitamin C	5	25
Nigella sativa (aka Black Seed)	4	23
DHA (Docosahexaenoic Acid)	3	22
Artichoke	2	20
Carotenoids	2	20
Flaxseed	2	20
Garlic	2	20
Green Tea	8	20
Tea: Black	1	20
Tea: Green	1	20
Ginsenosides	10	18
Polyphenols	6	18
Anthocyanins	5	17
Cryptoxanthin	6	17
Fucoidan	5	17
Turmeric	5	17
Black Currant	4	16
Pomegranate	5	16
Resveratrol	5	16
Genistein	4	15
Cannabinoids	3	14
Chlorogenic Acid	3	14
Licorice	3	14
Luteolin	3	14
Lycopene	8	14
Spirulina	3	14
Bilberry	3	13
Fucoxanthin	3	13
Prebiotics	3	13
Astaxanthin	8	12
Blue Honeysuckle	6	12
Cannabis	2	12
Chia	2	12
Chicory	2	12
Coenzyme Q10	2	12
Hydrogen Water	2	12
Silibinin	7	12
Thymoquinone	2	12
Chocolate	2	11
Lutein	2	11
Nuts	2	11
Alpha-Carotene	1	10
Barberry	1	10
Calcium	1	10
Chlorella (Algae)	1	10
Cocoa	1	10
Curcuminoids	1	10
Fermented Foods and Beverages	5	10
Fiber	1	10
Hesperidin	1	10
Hibiscus sabdariffa	1	10
Magnesium	1	10
Nuts: All	1	10
Orange	1	10
Piperine	1	10
Raisins	1	10
Selenium	1	10
Zataria multiflora	1	10
Zeaxanthin	1	10
beta-Carotene	1	10
Lactobacillus paracasei	4	8
Paeoniflorin	4	8
Betulinic acid	4	7
Blueberry	4	7
Flavonoids	4	7
Kefir	4	7
Lactobacillus rhamnosus GG	4	7
Astragaloside	2	6
Babchi	3	6
Beta Sitosterol	3	6
Carnosic Acid	3	6
FOS (Fructooligosaccharides)	3	6
Fisetin	3	6
Hawthorn	3	6
Lemon Balm	3	6
Mangiferin	3	6
Naringenin	4	6
Nobiletin	4	6
Rose	3	6
Chinese Skullcap	1	5
Chokeberry	3	5
Gynostemma	3	5
Loquat	3	5
Panax Notoginseng	3	5
Quercetin	3	5
Tomatidine	3	5
Cannabidiol	2	4
Chrysin	2	4
Citrulline	2	4
Citrus Peel	2	4
Cordyceps Militaris	2	4
Cranberry	2	4
Crocin	2	4
EGCG (Epigallocatechin gallate)	2	4
Flaxseed Oil	2	4
Gastrodin	2	4
Ginger	2	4
Gingerol	2	4
Ginkgo biloba	2	4
Ginseng	2	4
Glycyrrhizin	2	4
Honeysuckle	2	4
Honokiol	2	4
Kombucha Tea	2	4
Lactobacillus plantarum	2	4
Mulberry	2	4
Myricetin	2	4
Procyanidin B2	2	4
Rosmarinic acid	2	4
Saffron	2	4
Stigmasterol	2	4
Ursolic Acid	2	4
Avocado	2	3
Berbamine	2	3
Beta-Caryophyllene	2	3
Black Tea	2	3
L-Carnitine	2	3
Lotus	2	3
Milk Thistle	2	3
Moringa oleifera	2	3
Royal Jelly	2	3
Strawberry	2	3
Tetrahydrocurcumin	2	3
Vitamin E: alpha tocopherol	2	3
Xanthohumol	2	3
Acerola	1	2
Adlay	1	2
Algae	1	2
Aloe Vera	1	2
Alpha Linolenic Acid	1	2
Alpha-Lipoic Acid	1	2
Anise	1	2
Apigenin	1	2
Apple Cider Vinegar	1	2
Ashwagandha	1	2
Asiatic Acid	1	2
Banaba	1	2
Banana	1	2
Barley	1	2
Basil	1	2
Bee Pollen	1	2
Bee Venom	1	2
Bergamot	1	2
Bergamot orange	1	2
Bifidobacterium Lactis	1	2
Bisdemethoxycurcumin	1	2
Bitter Melon	1	2
Broccoli	1	2
Burdock	1	2
Caffeine	1	2
Camel Milk	1	2
Carnosine	1	2
Catechin	2	2
Cherry: All Varieties	1	2
Choline	1	2
Cinnamon	1	2
Citrus naringin	1	2
D-Limonene	1	2
Diosgenin	1	2
Diosmin	1	2
Dong Quai	1	2
Dragon Fruit	1	2
EPA (Eicosapentaenoic Acid)	1	2
Eucalyptus	1	2
Eugenol	1	2
Fenugreek	1	2
Ferulic acid	1	2
Feverfew	1	2
Formononetin	1	2
Fructose	1	2
Galacto-oligosaccharides	1	2
Genipin	1	2
Goji	1	2
Grapefruit	1	2
Green Coffee Bean	1	2
Hazelnut	1	2
Hops	1	2
Isoliquiritigenin	1	2
Isothiocyanates	1	2
Krill	1	2
Lactobacillus casei: Shirota	1	2
Lactobacillus fermentum	1	2
Lactobacillus probiotics	1	2
Maitake Mushroom	1	2
Mangosteen	1	2
Motherwort	1	2
Mung Bean	1	2
Oleanolic acid	1	2
Oleuropein	1	2
Olive Oil	2	2
Onion	1	2
Orange: Mandarin	1	2
Parthenolide	1	2
Patchouli	1	2
Phyllanthus emblica	1	2
Pomegranate Peel	1	2
Pomegranate flower	1	2
Pterostilbene	1	2
Puerarin	1	2
Pumpkin Seeds	1	2
Pycnogenol (Pine Bark)	1	2
Radish	1	2
Raspberry	1	2
Raspberry ketone	1	2
Red Cabbage	1	2
Red Sage	1	2
Reishi Mushroom	1	2
Rosemary	1	2
Rutin	1	2
Salvia miltiorrhiza	1	2
Seaweed: Brown	1	2
Sesamin	1	2
Shikonin	1	2
Spinach	1	2
Star Fruit	1	2
Sulforaphane	1	2
Sweet Potato	1	2
Tangeretin	1	2
Tomato	1	2
Virgin Coconut Oil	1	2
Vitamin B-3 (Niacin)	1	2
Vitamin E: Gamma-tocotrienol	1	2
Vitexins	1	2
Wogonin	1	2
Xanthones	1	2
Apple Polyphenols	1	1
Arctigenin	1	1
B-Carotene	1	1
Benzyl isothiocyanate	1	1
Blackberry	1	1
Carnosol	1	1
Crocetin	1	1
Dihydrocurcumin	1	1
Fish	1	1
Fish Oil	1	1
Mugwort	1	1
Nicotinamide adenine dinucleotide (NADH)	1	1
Punicalagin	1	1
Quinoa	1	1
Red Wine Extract	1	1
S-Adenosylmethionine (SAMe)	1	1
Safflower	1	1
Thistle	1	1
Toona sinensis	1	1
Walnut	1	1
Wormwood	1	1

Name	AC	CK
Bisphenol A	7	45
Sugar Sweetened Beverages	2	40
Fructose	16	33
High Fructose Corn Syrup	12	26
Artificially Sweetened Beverages	1	10
Insulin	1	10
Phthalates	1	10
Tamoxifen	1	10
Glyphosate	2	5
Trans Fatty Acids	3	5
Bisphenol S	2	4
Monosodium Glutamate (MSG)	2	4
Bisphenol F	1	2
Irinotecan	1	2
Roundup (herbicide)	1	2
Aluminum	1	1
Retinyl palmitate	1	1
Sugary soda	1	1

Name	AC	CK
Exercise	7	47
Dietary Modification: Mediterranean Diet	3	12
Dietary Modification: Low Carbohydrate/Ketogenic	1	10
Electroacupuncture	1	10
Exercise: Aerobic	1	10
Fasting/Caloric Restriction	1	10
Integrative Medicine	1	10
Lifestyle Changes: Positive	1	10
Dietary Modification: Vegetarian	1	3
Acupuncture	1	2
Dietary Modification: Low Glycemic Diet	1	1
Dietary Modification: Wheat/Gluten Free	1	1

Name	AC	CK	Focus
Western Diet	8	15

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Complement Ther Med. 2020 Jan ;48:102283. Epub 2019 Dec 17. PMID: 31987259

Article Published Date : Dec 31, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents, Hypolipidemic

[+]

Effect of green coffee bean extract supplementation on liver function and inflammatory biomarkers.Apr 30, 2021

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Pubmed Data : Complement Ther Clin Pract. 2021 May ;43:101349. Epub 2021 Mar 4. PMID: 33714861

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Pubmed Data : Clin Nutr. 2016 Dec 23. Epub 2016 Dec 23. PMID: 28040302

Article Published Date : Dec 22, 2016

Study Type : Meta Analysis, Review

Additional Links

Substances : Omega-3 Fatty Acids, Polyunsaturated Fatty Acids (PUFAs)

Diseases : Hepatic Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Silymarin has positive efficacy to reduce transaminases levels in NAFLD patients.Nov 30, 2017

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Pubmed Data : Medicine (Baltimore). 2015 May ;94(20):e758. PMID: 25997043

Article Published Date : Apr 30, 2015

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Bilberry, Black Currant

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypoglycemic Agents

Additional Keywords : Significant Treatment Outcome

[+]

A higher dietary vitamin C intake might help reduce the risk of non-alcoholic fatty liver disease.Dec 31, 2015

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Pubmed Data : Gastroenterology. 2018 Mar 28. Epub 2018 Mar 28. PMID: 29604292

[+]

Calcium plus calcitriol supplementation for 12 weeks may be potentially effective for biochemical parameters in NAFLD patients. Sep 27, 2016

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Pubmed Data : Clin Nutr. 2016 Sep 28. Epub 2016 Aug 28. PMID: 27720403

Article Published Date : Sep 27, 2016

Study Type : Human Study

Additional Links

Substances : Calcium, Vitamin D

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hypoglycemic Agents

[+]

Chia-supplemented diet ameliorates non-alcoholic fatty liver disease and its metabolic abnormalities in humans.May 18, 2020

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Curcumin prevented the development of immunological alterations in NAFLD.Dec 31, 2016

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Pubmed Data : BMJ Open. 2019 Sep 4 ;9(9):e028961. Epub 2019 Sep 4. PMID: 31488477

[+]

Exercise overcomes skeletal muscle insulin resistance. Aug 01, 2011

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Pubmed Data : Proc Natl Acad Sci U S A. 2011 Aug 1. Epub 2011 Aug 1. PMID: 21808028

Article Published Date : Aug 01, 2011

Study Type : Human Study

Additional Links

Diseases : Fatty Liver, Insulin Resistance, Metabolic Syndrome X, Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Exercise

Pharmacological Actions : Insulin Sensitizers

[+]

Flaxseed oil in the context of a weight loss program ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease.Jan 28, 2020

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Pubmed Data : Br J Nutr. 2020 Jan 29:1-24. Epub 2020 Jan 29. PMID: 31992372

Article Published Date : Jan 28, 2020

Study Type : Human Study

Additional Links

Substances : Flaxseed

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

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Pubmed Data : Int J Food Sci Nutr. 2016 Jun ;67(4):461-9. Epub 2016 Mar 17. PMID: 26983396

Article Published Date : May 31, 2016

Study Type : Human Study

Additional Links

Substances : Flaxseed

Diseases : Insulin Resistance, Liver Fibrosis, Liver Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Integrative Medicine, Lifestyle Changes: Positive

Pharmacological Actions : Anti-Fibrotic, Enzyme Inhibitors, Hepatoprotective

Additional Keywords : Significant Treatment Outcome

[+]

Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5.Feb 28, 2019

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Pubmed Data : Med Hypotheses. 2019 Mar ;124:40-41. Epub 2019 Feb 4. PMID: 30798914

Article Published Date : Feb 28, 2019

Study Type : Human Study

Additional Links

Diseases : Chemically-Induced Liver Damage, Nonalcoholic fatty liver disease (NAFLD)

Problem Substances : High Fructose Corn Syrup

[+]

Fucoidan and fucoxanthin attenuate hepatic steatosis and inflammation of NAFLD.Mar 11, 2021

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Pubmed Data : Mar Drugs. 2021 Mar 12 ;19(3). Epub 2021 Mar 12. PMID: 33809062

Article Published Date : Mar 11, 2021

Study Type : Human Study

Additional Links

Substances : Fucoidan, Fucoxanthin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Interleukin-6 Downregulation

[+]

Garlic may reduce the amount of fat in the liver and prevent or delay the progression of NAFLD.Dec 31, 2015

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Pubmed Data : Adv Biomed Res. 2016 ;5:2. Epub 2016 Jan 27. PMID: 26955623

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Pubmed Data : Pak J Med Sci. 2017 Jul-Aug;33(4):931-936. PMID: 29067068

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2018 Nov 18 ;10(11). Epub 2018 Nov 18. PMID: 30453660

Article Published Date : Nov 17, 2018

Study Type : Human Study

Additional Links

Substances : Fiber

Diseases : Insulin Resistance, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Gastroprotective

Problem Substances : Insulin

[+]

Intake of nuts and seeds is associated with a lower prevalence of nonalcoholic fatty liver disease.Sep 14, 2021

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Pubmed Data : J Nutr. 2021 Sep 15. Epub 2021 Sep 15. PMID: 34522969

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Pubmed Data : PLoS One. 2020 ;15(12):e0244514. Epub 2020 Dec 31. PMID: 33382757

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : Nuts

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Risk Reduction

[+]

Obese children with small intestinal bacterial overgrowth have an increased risk for developing NAFLD.Oct 08, 2017

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Pubmed Data : J Pediatr Endocrinol Metab. 2017 Oct 9. Epub 2017 Oct 9. PMID: 28988228

Article Published Date : Oct 08, 2017

Study Type : Human Study

Additional Links

Diseases : Dysbiosis, Nonalcoholic fatty liver disease (NAFLD)

Additional Keywords : Increased Risk

[+]

Observations from this study suggest that cannabis use is associated with lower prevalence of NAFLD.Dec 31, 2016

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Pubmed Data : PLoS One. 2017 ;12(4):e0176416. Epub 2017 Apr 25. PMID: 28441459

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Additional Keywords : Risk Reduction, Significant Treatment Outcome

[+]

Pomegranate peel extract ameliorates metabolic syndrome risk factors in patients with non-alcoholic fatty liver disease.Aug 21, 2023

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Pubmed Data : Nutr J. 2023 Aug 22 ;22(1):40. Epub 2023 Aug 22. PMID: 37605174

Article Published Date : Aug 21, 2023

Study Type : Human Study

Additional Links

Substances : Pomegranate Peel

Diseases : Insulin Resistance, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anticholesteremic Agents, Antihypertensive Agents, Hepatoprotective, Hypolipidemic

Additional Keywords : Plant Extracts

[+]

Pro- and prebiotic effects on oxidative stress and inflammatory markers in non-alcoholic fatty liver disease.Dec 31, 2017

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Pubmed Data : Food Funct. 2022 Nov 14 ;13(22):11568-11578. Epub 2022 Nov 14. PMID: 36263703

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Pubmed Data : PLoS One. 2016 ;11(6):e0157515. Epub 2016 Jun 10. PMID: 27284686

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Nonalcoholic fatty liver disease (NAFLD), Vitamin D Deficiency

Additional Keywords : Risk Factors, Risk Reduction

[+]

Serum carotenoids are inversely associated with prevalence of NAFLD in middle aged and elderly Chinese.Dec 31, 2014

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Pubmed Data : Clin Mol Hepatol. 2015 Dec ;21(4):379-86. Epub 2015 Dec 24. PMID: 26770927

Article Published Date : Nov 30, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin E

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Silymarin in non-cirrhotics with non-alcoholic steatohepatitis.Dec 31, 2018

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Pubmed Data : Ann Gastroenterol. 2014 ;27(4):387-394. PMID: 25331487

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Spirulina

Diseases : Nonalcoholic fatty liver disease (NAFLD), Quality of Life: Poor

Pharmacological Actions : Hepatoprotective, Hypolipidemic

Additional Keywords : Significant Treatment Outcome

[+]

Supplementation of 500 mg resveratrol, along with lifestyle modification, is superior to lifestyle modification alone.Sep 30, 2014

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Pubmed Data : Nutr Res. 2014 Oct ;34(10):837-43. Epub 2014 Sep 23. PMID: 25311610

Article Published Date : Sep 30, 2014

Study Type : Human Study

Additional Links

Substances : Resveratrol

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Plant Extracts, Significant Treatment Outcome

[+]

Supplementation of Lycium barbarum polysaccharide combined with aerobic exercise ameliorates high-fat-induced nonalcoholic steatohepatitis.Aug 07, 2022

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Pubmed Data : Nutrients. 2022 Aug 8 ;14(15). Epub 2022 Aug 8. PMID: 35956423

Article Published Date : Aug 07, 2022

Study Type : Human Study

Additional Links

Substances : Goji

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Exercise: Aerobic

Pharmacological Actions : Antioxidants, Hepatoprotective

Additional Keywords : Polysaccharides

[+]

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Turmeric effectively improved SIRT1 levels in patients with NAFLD compared with the placebo.Mar 30, 2022

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Pubmed Data : Prev Nutr Food Sci. 2022 Mar 31 ;27(1):37-44. PMID: 35465117

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Pubmed Data : J Assoc Physicians India. 2019 Aug ;67(8):52-56. PMID: 31562717

Article Published Date : Jul 31, 2019

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Inflammation, Nonalcoholic fatty liver disease (NAFLD), Vitamin D Deficiency

Additional Keywords : Increased Risk

[+]

Vitamin D levels are inversely associated with the severity of NAFLD.Dec 31, 2018

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Pubmed Data : Nutr Res. 2016 Jan ;36(1):57-64. Epub 2015 Oct 31. PMID: 26773781

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Pubmed Data : Nutr Res Pract. 2018 Apr ;12(2):110-117. Epub 2018 Mar 22. PMID: 29629027

Article Published Date : Mar 31, 2018

Study Type : Animal Study

Additional Links

Substances : Onion

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Plant Extracts

[+]

Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease.Sep 13, 2019

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Ameliorative effects of Compound K and ginsenoside Rh1 on non-alcoholic fatty liver disease in rats.Jan 19, 2017

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Pubmed Data : Sci Rep. 2017 Jan 20 ;7:41144. Epub 2017 Jan 20. PMID: 28106137

Article Published Date : Jan 19, 2017

Study Type : Animal Study

Additional Links

Substances : Ginsenosides, Panax Notoginseng

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Ginsenosides, Hepatoprotective, Nonalcoholic fatty liver disease (NAFLD), Panax Notoginseng

[+]

Ameliorative effects of high intensity interval training and Lactobacillus rhamnosus GG Protect against tetracycline-induced fatty liver.Dec 31, 2021

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Pubmed Data : EXCLI J. 2022 ;21:991-1006. Epub 2022 Jul 21. PMID: 36110559

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Lactobacillus rhamnosus GG

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor

Additional Keywords : Gene Expression Regulation

[+]

An anti-angiogenic compound from lemon balm leaves attenuates a high-fat diet-induced nonalcoholic fatty liver disease.Apr 17, 2017

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Pubmed Data : PLoS One. 2017 ;12(1):e0169685. Epub 2017 Jan 12. PMID: 28081181

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Chokeberry

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hypolipidemic, Superoxide Dismutase Up-regulation

Additional Keywords : Plant Extracts

[+]

Ascorbic acid inhibits visceral obesity and nonalcoholic fatty liver disease.Oct 02, 2018

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Pubmed Data : Int J Obes (Lond). 2018 Oct 3. Epub 2018 Oct 3. PMID: 30283077

Astaxanthin prevents diet-induced NASH progression by shaping intrahepatic immunity. Oct 12, 2021

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Pubmed Data : Food Funct. 2023 Feb 8. Epub 2023 Feb 8. PMID: 36752061

Article Published Date : Feb 07, 2023

Study Type : Animal Study

Additional Links

Substances : Baicalein, Flavonoids

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Baicalein enhances the effect of acarbose on the improvement of nonalcoholic fatty liver disease associated with prediabetes.Aug 31, 2021

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Pubmed Data : Gastroenterol Rep (Oxf). 2023 ;11:goad032. Epub 2023 Jun 6. PMID: 37293270

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, SIRT1 Activator

[+]

Berberine alleviates non-alcoholic steatohepatitis through modulating gut microbiota mediated intestinal FXR activation.Dec 31, 2020

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Pubmed Data : PLoS One. 2015 ;10(8):e0134172. Epub 2015 Aug 7. PMID: 26252777

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Metabolic Diseases, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Gene Expression Regulation

[+]

Berberine ameliorates nonalcoholic fatty liver disease by decreasing the liver lipid content.Sep 30, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Front Pharmacol. 2022 ;13:913378. Epub 2022 Jul 8. PMID: 35873595

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Gastrointestinal Agents, Hypolipidemic

[+]

Bergamot polyphenols boost therapeutic effects of the diet on non-alcoholic steatohepatitis induced by junk food.Oct 31, 2018

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Pubmed Data : Nutrients. 2018 Nov 1 ;10(11). Epub 2018 Nov 1. PMID: 30388763

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Pubmed Data : Int Immunopharmacol. 2021 Sep ;98:107915. Epub 2021 Jun 29. PMID: 34198236

Article Published Date : Aug 31, 2021

Study Type : Animal Study

Additional Links

Substances : Patchouli

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Hypolipidemic

[+]

Betaine alleviates high-fat diet-induced disruptionof hepatic lipid and iron homeostasis.Jun 02, 2022

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Black ginseng protects against Western diet-induced nonalcoholic steatohepatitis.Sep 30, 2022

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Pubmed Data : J Food Biochem. 2022 Oct 1:e14432. Epub 2022 Oct 1. PMID: 36183169

Article Published Date : Sep 30, 2022

Study Type : Animal Study

Additional Links

Substances : Ginseng

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

Anti Therapeutic Actions : Western Diet

[+]

Blackcurrant extract prevents dyslipidemia and hepatic steatosis.May 24, 2020

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Pubmed Data : Food Res Int. 2021 May ;143:110240. Epub 2021 Feb 25. PMID: 33992352

Article Published Date : Apr 30, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic Acid

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Hepatoprotective

[+]

Click here to read the entire abstract

Pubmed Data : Food Funct. 2022 Feb 25. Epub 2022 Feb 25. PMID: 35212695

Article Published Date : Feb 24, 2022

Study Type : Animal Study

Additional Links

Substances : Lemon

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Citrus peel extract ameliorates high-fat diet-induced NAFLD.Feb 29, 2020

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Pubmed Data : J Nutr Biochem. 2021 06 ;92:108618. Epub 2021 Mar 9. PMID: 33711421

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Cocoa

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Coffee prevents fatty liver disease induced by a high-fat diet by modulating pathways of the gut-liver axis.Dec 31, 2018

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Pubmed Data : J Nutr Sci. 2019 ;8:e15. Epub 2019 Apr 22. PMID: 31037218

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Coffee

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective

Additional Keywords : Gut-liver axis

[+]

Coix lacryma-jobi seed oil reduces fat accumulation in nonalcoholic fatty liver disease.Apr 30, 2021

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Pubmed Data : J Oleo Sci. 2021 May 1 ;70(5):685-696. Epub 2021 Apr 12. PMID: 33840662

Article Published Date : Apr 30, 2021

Study Type : Animal Study

Additional Links

Substances : Adlay

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

[+]

Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease.Oct 31, 2021

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Pubmed Data : Saudi Pharm J. 2021 Nov ;29(11):1303-1313. Epub 2021 Oct 6. PMID: 34819792

Article Published Date : Oct 31, 2021

Study Type : Animal Study

Additional Links

Substances : Raspberry

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

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View the Evidence: 823 Abstracts with Nonalcoholic fatty liver disease (NAFLD) Research

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Effects of artichoke supplementation on liver enzymes.Jun 30, 2022

Nigella sativa and health outcomes: An overview of systematic reviews and meta-analyses.Dec 31, 2022

Sulforaphane ameliorates lipid profile.Apr 07, 2021

Therapeutic potential of artichoke in the treatment of fatty liver.Sep 30, 2022

Acupuncture may be effective and safe for treatment of NAFLD.Sep 23, 2021

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

Effect of green coffee bean extract supplementation on liver function and inflammatory biomarkers.Apr 30, 2021

Effect of Nigella sativa in the treatment of nonalcoholic fatty liver disease/Mar 15, 2021

Impact of silymarin in individuals with nonalcoholic fatty liver disease.Dec 31, 2020

Med-Diet is a beneficial pharmaconutritional therapy in patients with NAFLD. Jun 18, 2021

Physical activity reduces intrahepatic lipid content and markers of hepatocellular injury in patients with NAFLD.May 03, 2016

Polyunsaturated fatty acids supplementation can improve liver steatosis and liver functions.Dec 22, 2016

Silymarin has positive efficacy to reduce transaminases levels in NAFLD patients.Nov 30, 2017

Studies on coffee and NAFLD suggest that coffee consumption could have a protective role on fibrosis.Mar 29, 2016

The consumption of sugar-sweetened beverages has a dose-dependent effect on the risk of NAFLD.Jun 20, 2019

The systematic review and meta-analysis support that probiotics are superior to placebo in NAFLD patients.Dec 31, 2018

These results found a significantly decreased risk of NAFLD among coffee drinkers and significantly decreased risk of liver fibrosis.Nov 06, 2016

This meta-analysis supports a positive significant association between higher consumption of sugar sweetened beverages and NAFLD.May 13, 2018

Vitamin E significantly improved liver function and histologic changes in patients with NAFLD/NASH.Jun 30, 2015

Vitamin E supplementation in the treatment on nonalcoholic fatty liver disease.Dec 31, 2022

8 weeks of provision of a diet low in free sugar content compared with usual diet resulted in significant improvement in hepatic steatosis.Jan 21, 2019

A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients. Apr 30, 2015

A higher dietary vitamin C intake might help reduce the risk of non-alcoholic fatty liver disease.Dec 31, 2015

Alternate-day fasting appears to be an effective diet therapy for individuals with NAFLD that can achieve weight loss and improvement of dyslipidaemia.Dec 17, 2019

Altilix supplementation was a beneficial approach in the management of hepatic and cardiometabolic alterations in metabolic syndrome subjects.Oct 24, 2019

An improved diet is particularly important for individuals with a high genetic risk for NAFLD.Mar 27, 2018

Antioxidant activity of hydroxytyrosol and vitamin E reduces systemic inflammation in children with paediatric NAFLD.Oct 11, 2020

Artichoke leaf extracts have benefits in the management of NASH.Dec 31, 2015

Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD.Nov 30, 2018

Beneficial effects of supplementation with microalgae Chlorella vulgaris in patients with non-alcoholic fatty liver disease.Jul 31, 2017

Berberis extract can be used as a supplementary medication in treating NAFLD.Jan 31, 2015

Calcium plus calcitriol supplementation for 12 weeks may be potentially effective for biochemical parameters in NAFLD patients. Sep 27, 2016

Chia-supplemented diet ameliorates non-alcoholic fatty liver disease and its metabolic abnormalities in humans.May 18, 2020

Chlorella vulgaris supplementation have therapeutic value in patients with non-alcoholic fatty liver disease.Oct 31, 2012

Cocoa polyphenols improve endothelial function via Nox2 down-regulation in NASH patients.Nov 12, 2017

Combined phthalates influence on glucose and lipid metabolism may increase the possibility for NAFLD and insulin resistance development.Dec 05, 2019

Consumption of fruits that are high in antioxidants could represent a useful means to improve the antioxidant status of NAFLD.Jul 13, 2016

Consumption of hibiscus sabdariffa extracts reduced obesity, abdominal fat, serum FFA and improved liver steatosis.Mar 31, 2014

Consumption of Nigella sativa can reduce the inflammatory biomarkers in patients with NAFLD.May 31, 2019

CoQ10 supplement at a dosage of 100 mg could be effective for improving the systemic inflammation and biochemical variables in NAFLD.Jul 08, 2015

Cranberry supplementation had a positive effect on some lipid profiles, insulin resistance, and hepatic steatosis in patients with NAFLD.Nov 18, 2021

Curcumin prevented the development of immunological alterations in NAFLD.Dec 31, 2016

curcumin supplementation can improve serum levels of inflammatory cytokines in subjects with NAFLD.Feb 29, 2020

Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease.Jul 31, 2020

Delta-tocotrienol was safe, and it effectively improved aminotransferase levels and inflammatory and oxidative stress markers in patients with NAFLD.Dec 31, 2017

DHA supplementation improves liver steatosis in children with NAFLD. Oct 31, 2013

Dietary vitamin C intake is associated with improved liver function and glucose metabolism in Chinese adults.Dec 31, 2020

Dietary Vitamin E intake is associated with a reduced risk of developing digestive diseases and NAFLD.Mar 13, 2022

Diets with a higher intake of nuts may be associated with a decreased risk of NAFLD.Sep 03, 2019

Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity.Mar 14, 2017

Effect of garlic powder supplementation on hepatic steatosis, liver enzymes and lipid profile in patients with non-alcoholic fatty liver disease.Jan 27, 2020

Effect of Korea red ginseng on nonalcoholic fatty liver disease.Feb 28, 2021

Effect of vitamin D supplementation on various parameters in non-alcoholic fatty liver disease patients.Apr 30, 2019

Effects of naringenin supplementation on cardiovascular risk factors in overweight/obese patients with nonalcoholic fatty liver disease.Dec 02, 2021

Effects of oral vitamin C supplementation on liver health and associated parameters.Dec 31, 2020

Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease.Jun 30, 2018

Electroacupuncture and aerobic interval training exercise are potent modalities that improve liver functions in people with Nonalcoholic fatty liver disease.Oct 28, 2019

Exercise in the management of metabolic-associated fatty liver disease. Sep 10, 2023

Exercise overcomes skeletal muscle insulin resistance. Aug 01, 2011

Flaxseed oil in the context of a weight loss program ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease.Jan 28, 2020

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5.Feb 28, 2019

Fucoidan and fucoxanthin attenuate hepatic steatosis and inflammation of NAFLD.Mar 11, 2021

Garlic may reduce the amount of fat in the liver and prevent or delay the progression of NAFLD.Dec 31, 2015

Garlic powder supplementation improved risk factors of NAFLD. May 31, 2020

Genistein can reduce insulin resistance, oxidative and inflammatory indices along with improvement in fat metabolism in patients with NAFLD.May 31, 2017

Green tea extract therapy resulted in significant improvement in metabolic, chemical, inflammatory and radiological parameters of NAFLD patients.Jun 30, 2017

Hesperidin supplementation accompanied with lifestyle modification is superior to lifestyle modification alone in management of NAFLD.Jun 30, 2019

High intake of magnesium may be associated with reduced risks of fatty liver disease and prediabetes.Apr 01, 2018

High levels of urinary BPA were associated with NAFLD in a nationally representative sample of adults in the US.Mar 28, 2019

Higher intake and serum levels of most carotenoids were associated with lower odds of having NAFLD.May 16, 2019

HIIT is safe, feasible and efficacious for improving exercise capacity and peripheral insulin sensitivity in people with NASH.Dec 19, 2022

Nonalcoholic fatty liver disease (NAFLD)

View the Evidence:
823 Abstracts with Nonalcoholic fatty liver disease (NAFLD) Research