Obsessive-Compulsive Disorder

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28 Substances Researched for Obsessive-Compulsive Disorder
2 Problem Substances Researched for Obsessive-Compulsive Disorder
5 Therapeutic Actions Researched for Obsessive-Compulsive Disorder

View the Evidence:
70 Abstracts with Obsessive-Compulsive Disorder Research

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Pubmed Data : J Agric Food Chem. 2008 Sep 24;56(18):8601-8. Epub 2008 Aug 30. PMID: 11951146
Study Type : Human Study
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Pubmed Data : J Clin Psychiatry. 2009 Nov;70(11):1530-5. Epub 2009 Jun 30. PMID: 19573497
Study Type : Human Study
Additional Links
Substances : Caffeine
Additional Keywords : Natural Substances Versus Drugs
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Pubmed Data : Acta Psychiatr Scand. 1998 Dec;98(6):502-6. PMID: 9879795
Study Type : Human Study
Additional Links
Substances : Cannabinoids , Cannabis
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Pubmed Data : Hum Psychopharmacol. 2021 Feb 18:e2780. Epub 2021 Feb 18. PMID: 33599345
Study Type : Human Study
Additional Links
Substances : Crocin
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Natural Substances Versus Drugs
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Pubmed Data : Integr Cancer Ther. 2006 Dec;5(4):362-72. PMID: 19737592
Study Type : Human Study
Additional Links
Substances : Echium amoenum
Pharmacological Actions : Anxiolytic
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Pubmed Data : J Nerv Ment Dis. 2009 Aug;197(8):619-22. PMID: 19684500
Study Type : Human Study
Additional Links
Therapeutic Actions : Electroacupuncture
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Pubmed Data : Am J Psychiatry. 1996 Sep;153(9):1219-21. PMID: 8780431
Study Type : Human Study
Additional Links
Substances : Inositol
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Psychiatry. 2022 Jul-Aug;64(4):349-353. Epub 2022 Jul 13. PMID: 36060722
Study Type : Human Study
Additional Links
Substances : Vitamin D
Additional Keywords : Increased Risk
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Psychiatry. 2019 ;10:793. Epub 2019 Nov 11. PMID: 31780963
Study Type : Human Study
Additional Links
Therapeutic Actions : Kundalini Yoga
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Pubmed Data : CNS Spectr. 1999 Dec;4(12):34-47. PMID: 18311106
Study Type : Human Study
Additional Links
Therapeutic Actions : Yoga
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Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2010 Mar 17;34(2):362-365. Epub 2009 Dec 24. PMID: 20035818
Study Type : Human Study
Additional Links
Substances : Milk Thistle
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Pubmed Data : J Nerv Ment Dis. 2008 Oct;196(10):776-9. PMID: 18852623
Study Type : Human Study
Additional Links
Therapeutic Actions : Mindfullness Training
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Pubmed Data : Eur Arch Psychiatry Clin Neurosci. 2018 Nov 16. Epub 2018 Nov 16. PMID: 30446822
Study Type : Human Study
Additional Links
Therapeutic Actions : Mindfullness Training
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Pubmed Data : J Clin Psychopharmacol. 2012 Dec ;32(6):797-803. PMID: 23131885
Study Type : Human Study
Additional Links
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Pubmed Data : Digestion. 2008;78(4):224-8. Epub 2009 Jan 13. PMID: 16374600
Study Type : Human Study
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Pubmed Data : Am J Psychother. 2009;63(2):133-46. PMID: 19711767
Study Type : Human Study
Additional Links
Therapeutic Actions : Hypnosis
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Pubmed Data : Psychiatry Clin Neurosci. 2005 Oct;59(5):616-20. PMID: 16194269
Study Type : Human Study
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Pubmed Data : Turk J Med Sci. 2016 ;46(3):775-82. Epub 2016 Apr 19. PMID: 27513255
Study Type : Human Study
Additional Links
Substances : Arginine
Additional Keywords : Risk Factors
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Pubmed Data : J Clin Psychiatry. 2006 Nov ;67(11):1735-40. PMID: 17196053
Study Type : Human Study
Additional Links
Substances : Psilocybin
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Psychiatry. 2017 Jul ;12(3):154-162. PMID: 29062366
Study Type : Human Study
Additional Links
Additional Keywords : Natural Substances Versus Drugs
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Pubmed Data : Psychiatry Res. 2017 08 ;254:232-237. Epub 2017 Apr 21. PMID: 28477545
Study Type : Human Study
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2014 ;10:1671-5. Epub 2014 Sep 9. PMID: 25228807
Study Type : Human Study
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2018 ;9:675. Epub 2018 Apr 6. PMID: 29686658
Study Type : Human Study
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Pubmed Data : Psychiatry Clin Neurosci. 2023 Dec ;77(12):646-652. Epub 2023 Sep 27. PMID: 37646189
Study Type : Human Study
Additional Links
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Child Adolesc Psychopharmacol. 2019 Dec 3. Epub 2019 Dec 3. PMID: 31800306
Study Type : Human Study
Additional Links
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Pubmed Data : Eur Psychiatry. 2016 Dec 16 ;40:82-87. Epub 2016 Dec 16. PMID: 27992837
Study Type : Human Study
Additional Links
Additional Keywords : Risk Factors
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Pubmed Data : J Complement Integr Med. 2011 Oct 11 ;8. Epub 2011 Oct 11. PMID: 22718671
Study Type : Human Study
Additional Links
Substances : Valerian
Pharmacological Actions : GABA Modulators
Additional Keywords : Plant Extracts
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Pubmed Data : JAMA Psychiatry. 2017 Aug 1 ;74(8):833-840. PMID: 28636705
Study Type : Human Study
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Noro Psikiyatr Ars. 2016 Mar ;53(1):33-37. Epub 2016 Mar 1. PMID: 28360763
Study Type : Human Study
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Pubmed Data : Acta Psychiatr Scand. 1988 Jul;78(1):8-10. PMID: 3176999
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
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Pubmed Data : Complement Ther Med. 2016 Aug ;27:25-9. Epub 2016 Apr 9. PMID: 27515872
Study Type : Human Study
Additional Links
Substances : Ashwagandha
Additional Keywords : Plant Extracts
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Pubmed Data : Int J Neurosci. 1996 Mar;85(1-2):1-17. PMID: 8727678
Study Type : Human Study
Additional Links
Therapeutic Actions : Yoga
Additional Keywords : Drug Sparing
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Pubmed Data : Gen Hosp Psychiatry. 2012 Sep-Oct;34(5):578.e7-8. Epub 2012 Jan 9. PMID: 22227032
Study Type : Human: Case Report
Additional Links
Substances : Vitamin B-12
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Pubmed Data : J Anxiety Disord. 2009 Aug;23(6):836-40. Epub 2009 Mar 9. PMID: 19329277
Study Type : Human: Case Report
Additional Links
Substances : Multivitamin
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Pubmed Data : J Psychoactive Drugs. 2014 Nov-Dec;46(5):393-5. PMID: 25364991
Study Type : Human: Case Report
Additional Links
Substances : Psilocybin
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Pubmed Data : J Psychoactive Drugs. 2021 Apr-Jun;53(2):146-148. Epub 2020 Nov 22. PMID: 33225874
Study Type : Human: Case Report
Additional Links
Substances : Psilocybin
Additional Keywords : Significant Treatment Outcome
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Pubmed Data : J Formos Med Assoc. 2008 Jan;107(1):68-72. PMID: 18218580
Study Type : Human: Case Report
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Pubmed Data : Integr Med (Encinitas). 2018 Dec ;17(6):38-41. PMID: 31043927
Study Type : Human: Case Report
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Pubmed Data : Heliyon. 2022 Dec ;8(12):e12135. Epub 2022 Dec 6. PMID: 36536916
Study Type : Human: Case Report
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Pubmed Data : Pediatr Int. 2016 Jul ;58(7):646-8. Epub 2016 Jul 7. PMID: 27388777
Study Type : Human: Case Report
Additional Links
Substances : Vitamin D
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Pubmed Data : Neurotoxicology. 2023 Aug 5 ;98:61-85. Epub 2023 Aug 5. PMID: 37549874
Study Type : Animal Study
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Pubmed Data : Platelets. 2006 Feb;17(1):37-41. PMID: 20695034
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Cannabis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : N Am J Med Sci. 2010 Feb ;2(2):81-6. PMID: 22624119
Study Type : Animal Study
Additional Links
Substances : Curcumin
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : Life Sci. 2006 Mar 6 ;78(15):1720-5. Epub 2005 Oct 25. PMID: 16253279
Study Type : Animal Study
Additional Links
Substances : Bitter Orange
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Essential Oils
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Pubmed Data : J Basic Clin Physiol Pharmacol. 2018 Mar 21. Epub 2018 Mar 21. PMID: 29561730
Study Type : Animal Study
Additional Links
Substances : Genistein
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : Pharmacol Biochem Behav. 2023 Oct 5 ;232:173652. Epub 2023 Oct 5. PMID: 37804865
Study Type : Animal Study
Additional Links
Substances : Probiotics
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:993927. Epub 2022 Sep 16. PMID: 36188588
Study Type : Animal Study
Additional Links
Substances : Noni
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Pubmed Data : Eur Rev Med Pharmacol Sci. 2010 Jun;14(6):507-12. PMID: 20712257
Study Type : Animal Study
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Pubmed Data : Neurosci Lett. 2012 Oct 18 ;528(1):27-30. Epub 2012 Sep 7. PMID: 22985509
Study Type : Animal Study
Additional Links
Substances : Carotenoids, Crocin, Saffron
Additional Keywords : Phytotherapy, Plant Extracts
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Pubmed Data : Biosci Biotechnol Biochem. 2009 Aug;73(8):1866-8. Epub 2009 Aug 7. PMID: 19661714
Study Type : Animal Study
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Pubmed Data : Behav Pharmacol. 2018 Apr ;29(2 and 3 - Special Issue):211-224. PMID: 29194070
Study Type : Animal Study
Additional Links
Additional Keywords : Microbiota
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Pubmed Data : Behav Neurosci. 2018 Jul 9. Epub 2018 Jul 9. PMID: 29985009
Study Type : Animal Study
Additional Links
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Pubmed Data : Med Hypotheses. 2014 Feb ;82(2):163-6. Epub 2013 Dec 1. PMID: 24332563
Study Type : Review
Additional Links
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Gut-brain Axis
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Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jun 1 ;35(4):887-95. Epub 2011 Feb 23. PMID: 21352883
Study Type : Review
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Pubmed Data : Depress Anxiety. 2016 Mar ;33(3):171-8. Epub 2015 Dec 2. PMID: 26629974
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2016 Jul 27 ;5(8). Epub 2016 Jul 27. PMID: 27472373
Study Type : Review
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Pubmed Data : J Psychopharmacol. 2017 Mar ;31(3):287-302. Epub 2017 Jan 30. PMID: 28135888
Study Type : Review
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Pubmed Data : Neurotherapeutics. 2015 Sep 4. Epub 2015 Sep 4. PMID: 26341731
Study Type : Review
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Pubmed Data : Eur J Pharmacol. 2023 Oct 15 ;957:176014. Epub 2023 Aug 22. PMID: 37619786
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Jul 26 ;24(15). Epub 2023 Jul 26. PMID: 37569349
Study Type : Review
Additional Links
Substances : Probiotics
Therapeutic Actions : Microbiota Transfer Therapy
Additional Keywords : Gut-brain Axis
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Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2002 Jan;26(1):21-32. PMID: 11853115
Study Type : Review
Additional Links
Substances : Myo-inositol
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Pubmed Data : Curr Pharm Des. 2018 04 17. Epub 2018 Apr 17. PMID: 29663874
Study Type : Review
Additional Links
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : Ann Pharmacother. 2022 Nov 16:10600280221138092. Epub 2022 Nov 16. PMID: 36384314
Study Type : Review
Additional Links
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Pubmed Data : Psychiatry Res. 2015 Sep 30 ;229(1-2):37-48. Epub 2015 Jun 6. PMID: 26296951
Study Type : Review
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Pubmed Data : Curr Top Behav Neurosci. 2021 Nov 17. Epub 2021 Nov 17. PMID: 34784024
Study Type : Review
Additional Links
Substances : Psilocybin
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Pubmed Data : Iran J Microbiol. 2023 Feb ;15(1):1-9. PMID: 37069911
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Pubmed Data : Curr Neuropharmacol. 2023 Feb 22. Epub 2023 Feb 22. PMID: 36815632
Study Type : Review
Additional Links
Substances : Prebiotics, Probiotics
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2023 Mar 24 ;15(4). Epub 2023 Mar 24. PMID: 37111543
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Porto Biomed J. 2021 Jan-Feb;6(1):e128. Epub 2021 Feb 11. PMID: 33884324
Study Type : Review
Additional Links
Substances : Psilocybin
Pharmacological Actions : Antidepressive Agents
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Pubmed Data : Psychiatr Pol. 2012 May-Jun;46(3):441-50. PMID: 23045897
Study Type : Review
Additional Links
Additional Keywords : Health Food

Obsessive-Compulsive Disorder Related Articles

Written by Sayer Ji, Founder
While millions practice yoga daily because they claim to experience tangible health benefits from it, skeptic holdouts claim only scientific evidence can separate out the placebo effect from reality. So, what does the Science say?
In research from Washington State University, cannabis led to reductions in compulsions by 60% and anxiety by 52%, with higher doses and greater CBD concentrations associated with greater benefits for obsessive-compulsive disorder
Written by Sayer Ji, Founder
While millions practice yoga daily because they claim to experience tangible health benefits from it, skeptic holdouts claim only scientific evidence can separate out the placebo effect from reality. So, what does the Science say?
Tests conducted by the FDA in 2008 found small amounts of ethylene glycol (EG) and diethylene glycol (DEG), also ingredients in antifreeze, in all batches of MiraLAX that were tested
Tests conducted by the FDA in 2008 found small amounts of ethylene glycol (EG) and diethylene glycol (DEG), also ingredients in antifreeze, in all batches of MiraLAX that were tested
In research from Washington State University, cannabis led to reductions in compulsions by 60% and anxiety by 52%, with higher doses and greater CBD concentrations associated with greater benefits for obsessive-compulsive disorder
According to a 2017 study, a staggering 12.7 percent of all US citizens over the age of 12 were taking antidepressants
Obsessive-compulsive disorder (OCD) is often treated with drugs that are ineffective and unsafe. Natural treatments, from saffron and milk thistle to B vitamins and electroacupuncture, have shown promise for improving symptoms
According to a 2017 study, a staggering 12.7 percent of all US citizens over the age of 12 were taking antidepressants
What if a common, affordable spice worked as well or better than antidepressants for mood disorders and anxiety--minus the dangerous side effects? Emerging research on saffron challenges pharmaceutical dominance over psychiatry
Written by Kelly Brogan, M.D.
Every functional medicine psychiatrist has case stories of the 'probiotic cure' – of a patient whose debilitating symptoms remitted completely with dietary change and probiotic supplementation
Obsessive-compulsive disorder (OCD) is often treated with drugs that are ineffective and unsafe. Natural treatments, from saffron and milk thistle to B vitamins and electroacupuncture, have shown promise for improving symptoms
What if a common, affordable spice worked as well or better than antidepressants for mood disorders and anxiety--minus the dangerous side effects? Emerging research on saffron challenges pharmaceutical dominance over psychiatry
Written by Kelly Brogan, M.D.
Every functional medicine psychiatrist has case stories of the 'probiotic cure' – of a patient whose debilitating symptoms remitted completely with dietary change and probiotic supplementation

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