Oral Lichen Planus

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24 Substances Researched for Oral Lichen Planus
NameACCKFocus
Aloe Vera532Locked
Purslane220Locked
Vitamin C220Locked
homeopathic medicine: ignatia120Locked
Vitamin D316Locked
Turmeric312Locked
Curcumin211Locked
Chamomile110Locked
Coconut110Locked
Coenzyme Q10110Locked
Colostrum110Locked
Curcuminoids110Locked
Echinacea110Locked
Nigella sativa (aka Black Seed)110Locked
Selenium110Locked
Spirulina110Locked
Vitamin E110Locked
Astaxanthin15Locked
Black Pepper12Locked
Peony22Locked
Baicalein11Locked
Paeoniflorin11Locked
Probiotics11Locked
Quercetin11Locked
4 Problem Substances Researched for Oral Lichen Planus
NameACCKFocus
Statin Drugs213Locked
Gluten110Locked
Simvastatin13Locked
Thimerosal 13Locked
4 Therapeutic Actions Researched for Oral Lichen Planus
NameACCKFocus
Laser Treatment: Low-Level652Locked
Homeopathic Treatment120Locked
Photodynamic therapy120Locked
Integrative Medicine110Locked
1 Problematic Actions Researched for Oral Lichen Planus
NameACCKFocus
Vaccination: Hepatitis B13Locked

View the Evidence:
43 Abstracts with Oral Lichen Planus Research

[+]

Low-level laser therapy seems to be a reliable alternative to corticosteroids for treating the oral lichen planus without the adverse effects.Jul 09, 2018

Pubmed Data : Photodiagnosis Photodyn Ther. 2018 Jul 10. Epub 2018 Jul 10. PMID: 30006319
Article Published Date : Jul 09, 2018
Study Type : Meta Analysis, Review
Additional Links
Diseases : Oral Lichen Planus
Therapeutic Actions : Photobiomodulation, Photodynamic therapy
[+]

Aloe gel may provide a safe and effective alternative treatment for patients with oral lichen planus.Mar 01, 2008

Pubmed Data : Br J Dermatol. 2008 Mar;158(3):573-7. Epub 2007 Dec 17. PMID: 18093246
Article Published Date : Mar 01, 2008
Study Type : Human Study
Additional Links
Substances : Aloe Vera
Diseases : Lichen Planus
[+]

Aloe gel may provide a safe and effective alternative treatment for patients with vulval lichen planus.Oct 01, 2008

Pubmed Data : J Coll Physicians Surg Pak. 2008 Oct;18(10):612-4. PMID: 18940117
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Substances : Aloe Vera
Diseases : Lichen Planus
[+]

Bovine Colostrum has beneficial effects in Sjogren's syndrome and oral lichen planus.Mar 01, 2002

Pubmed Data : Clin Oral Investig. 2002 Mar;6(1):11-20. PMID: 11996158
Article Published Date : Mar 01, 2002
Study Type : Human Study
Additional Links
Substances : Colostrum
Diseases : Oral Lichen Planus, Sjogren's Syndrome
[+]

Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus.Sep 18, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Oral Health. 2023 Sep 19 ;23(1):678. Epub 2023 Sep 19. PMID: 37726676
Article Published Date : Sep 18, 2023
Study Type : Human Study
Additional Links
Substances : Purslane
Diseases : Oral Lichen Planus
Pharmacological Actions : Immunomodulatory
Additional Keywords : Significant Treatment Outcome
[+]

Curcuma Longa in the Treatment of Symptomatic oral lichen planus.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Dermatol. 2022 ;67(4):478. PMID: 36578734
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Oral Lichen Planus
[+]

Curcumin exhibits anti-pre-cancer activity by increasing levels of vitamins C and E, and preventing lipid peroxidation and DNA damage.Jan 01, 2010

Pubmed Data : J Oral Sci. 2010;52(2):251-6. PMID: 20587949
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Curcumin, Vitamin C, Vitamin E
Diseases : DNA damage, Leukoplakia, Lichen Planus, Oxidative Stress, Precancerous Conditions
Pharmacological Actions : Antioxidants
[+]

Curcumin oral gel can bring about clinical improvements in patients with oral lichen planus.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Diagn Res. 2017 Apr ;11(4):ZC89-ZC93. Epub 2017 Apr 1. PMID: 28571271
Article Published Date : Mar 31, 2017
Study Type : Human Study
Additional Links
Substances : Curcuminoids
Diseases : Oral Lichen Planus
Therapeutic Actions : Integrative Medicine
[+]

Echinacea is an effective and complementary therapy for oral lichen planus.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dent Res J (Isfahan). 2022 ;19:98. Epub 2022 Nov 17. PMID: 36605140
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Echinacea
Diseases : Oral Lichen Planus
[+]

Homeopathic Ignatia has value in the treatment of oral lichen planus.Jan 01, 2009

Pubmed Data : Homeopathy. 2009 Jan;98(1):40-4. PMID: 19135958
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Substances : homeopathic medicine: ignatia
Diseases : Lichen Planus, Oral Lichen Planus
Therapeutic Actions : Homeopathic Treatment
[+]

Increased prevalence of celiac disease in patients with oral lichen planus.Aug 04, 2014

Pubmed Data : Clin Oral Investig. 2014 Aug 5. Epub 2014 Aug 5. PMID: 25088620
Article Published Date : Aug 04, 2014
Study Type : Human Study
Additional Links
Diseases : Celiac Disease, Lichen Planus
Additional Keywords : Diseases that are Linked
Problem Substances : Gluten
[+]

Low level laser therapy is an effective and harmless modality for management of erosive-atrophic oral lichen planus.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Folia Med (Plovdiv). 2018 Sep 1 ;60(3):417-424. PMID: 30355837
Article Published Date : Aug 31, 2018
Study Type : Human Study
Additional Links
Diseases : Oral Lichen Planus
Therapeutic Actions : Photobiomodulation
[+]

Lupus erythematosus and other autoimmune diseases related to statin therapy have been reported. Jan 01, 2007

Pubmed Data : J Eur Acad Dermatol Venereol. 2007 Jan ;21(1):17-24. PMID: 17207162
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Diseases : Autoimmune Diseases, Dermatomyositis, Lichen Planus, Lupus Erythematosus: Cutaneous, Polymyositis, Statin-Induced Pathologies
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Immunotoxic
[+]

Photobiomodulation versus corticosteroid in the management of erosive oral lichen planus.Feb 16, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Oral Health. 2024 Feb 17 ;24(1):246. Epub 2024 Feb 17. PMID: 38365694
Article Published Date : Feb 16, 2024
Study Type : Human Study
Additional Links
Diseases : Oral Lichen Planus
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
[+]

Purslane is well-tolerated and efficacious in treating oral ichen planus. Jul 07, 2009

Pubmed Data : Phytother Res. 2009 Jul 7. PMID: 19585472
Article Published Date : Jul 07, 2009
Study Type : Human Study
Additional Links
Substances : Purslane
Diseases : Oral Lichen Planus
[+]

Selenium can be proposed as a treatment for oral lichen planus.Apr 30, 2020

Pubmed Data : Oral Dis. 2020 May ;26(4):789-804. Epub 2020 Feb 10. PMID: 31975475
Article Published Date : Apr 30, 2020
Study Type : Human Study
Additional Links
Substances : Selenium
Diseases : Oral Lichen Planus
[+]

Spirulina 500 mg supplementation twice daily could be effective adjunct therapy with steroids to treat oral lichen planus.Apr 30, 2022

Pubmed Data : J Contemp Dent Pract. 2022 May 1 ;23(5):552-557. Epub 2022 May 1. PMID: 35986466
Article Published Date : Apr 30, 2022
Study Type : Human Study
Additional Links
Substances : Spirulina
Diseases : Oral Lichen Planus
[+]

The Coconut cream showed a significant decrease in the size of the lesion and the burning sensation with no side effects.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2022 ;54(2):84-89. PMID: 35546458
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Coconut
Diseases : Oral Lichen Planus
Additional Keywords : Significant Treatment Outcome
[+]

The role of vitamin D in amelioration of oral lichen planus.Jul 16, 2024

Pubmed Data : BMC Oral Health. 2024 Jul 17 ;24(1):813. Epub 2024 Jul 17. PMID: 39020381
Article Published Date : Jul 16, 2024
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Oral Lichen Planus
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The topical application of 2% chamomile gel is an effective treatment for oral lichen planus.Sep 30, 2016

Pubmed Data : J Eur Acad Dermatol Venereol. 2016 Oct ;30(10):1783-1786. Epub 2016 Jun 21. PMID: 27324515
Article Published Date : Sep 30, 2016
Study Type : Human Study
Additional Links
Substances : Chamomile
Diseases : Oral Lichen Planus
Additional Keywords : Significant Treatment Outcome
[+]

The topical application of Nigella sativa cream was effective and comparable to clobetasol propionate 0.05% gel in the management of OLP.Dec 21, 2022

Pubmed Data : Oral Maxillofac Surg. 2022 Dec 22. Epub 2022 Dec 22. PMID: 36547822
Article Published Date : Dec 21, 2022
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Oral Lichen Planus
Additional Keywords : Natural Substances Versus Drugs
[+]

The topical use of CoQ10 mucoadhesive tablets was as effective as the topical use of triamcinolone acetonide.Jul 20, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Oral Health. 2023 Jul 21 ;23(1):506. Epub 2023 Jul 21. PMID: 37480004
Article Published Date : Jul 20, 2023
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Oral Lichen Planus
Additional Keywords : Natural Substance Synergy
[+]

The urinary concentrations of ascorbic acid were significantly lower in patients with lichen planus which was associated with infections. Apr 18, 2017

Pubmed Data : J Immunoassay Immunochem. 2017 Apr 19. Epub 2017 Apr 19. PMID: 28422565
Article Published Date : Apr 18, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Oral Lichen Planus, Vitamin C Deficiency
Additional Keywords : Risk Factors
[+]

These findings indicate that photobiomodulation twice a week is as effective as corticoid therapy in treating oral lichen planus.Jun 30, 2021

Pubmed Data : Oral Dis. 2021 Jul ;27(5):1205-1216. Epub 2020 Oct 26. PMID: 33012017
Article Published Date : Jun 30, 2021
Study Type : Human Study
Additional Links
Diseases : Oral Lichen Planus
Therapeutic Actions : Photobiomodulation
[+]

Topical aloe vera improves quality of life in patients with oral lichen planus.Nov 01, 2010

Pubmed Data : J Oral Pathol Med. 2010 Nov;39(10):735-40. Epub 2010 Oct 4. PMID: 20923446
Article Published Date : Nov 01, 2010
Study Type : Human Study
Additional Links
Substances : Aloe Vera
Diseases : Oral Lichen Planus
[+]

Astaxanthin could be useful for improving chronic inflammation such as that associated with oral lichen planus.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2015 May ;56(3):171-8. Epub 2015 Jan 29. PMID: 26060346
Article Published Date : Apr 30, 2015
Study Type : Human In Vitro
Additional Links
Substances : Astaxanthin
Diseases : Oral Lichen Planus
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitamin D supplement may be a potential strategy for the oral lichen planus management.Feb 22, 2017

Pubmed Data : Oral Dis. 2017 Feb 23. Epub 2017 Feb 23. PMID: 28231625
Article Published Date : Feb 22, 2017
Study Type : Human In Vitro
Additional Links
Substances : Vitamin D
Diseases : Oral Lichen Planus
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Simvastatin-induced lichen planus pemphigoides has been observed. Feb 01, 2003

Pubmed Data : Ann Dermatol Venereol. 2003 Feb ;130(2 Pt 1):187-90. PMID: 12671581
Article Published Date : Feb 01, 2003
Study Type : Human: Case Report
Additional Links
Diseases : Lichen Planus, Lichenoid Dermatitis, Statin-Induced Pathologies
Problem Substances : Simvastatin, Statin Drugs
[+]

This report provides further documentation for a causal association linking the HBV vaccine with lichen planus.Dec 31, 2001

Pubmed Data : Dermatology. 2002 ;205(2):166-8. PMID: 12218234
Article Published Date : Dec 31, 2001
Study Type : Human: Case Report
Additional Links
Diseases : Lichen Planus
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
[+]

Piperine may be a novel and effective therapeutic strategy for oral lichen planus.Oct 19, 2018

Pubmed Data : Inflammopharmacology. 2018 Oct 20. Epub 2018 Oct 20. PMID: 30343451
Article Published Date : Oct 19, 2018
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Lichen Planus
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

According to the results of the studies, vitamin D deficiency may be associated with an increased risk of oral lichen planus lesions.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ethiop J Health Sci. 2020 Jul 1 ;30(4):615-622. PMID: 33897222
Article Published Date : Jun 30, 2020
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Oral Lichen Planus, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Aloe barbadensis can play a significant role in dentistry in treatment of lichen planus, oral submucous fibrosis, recurrent aphthous stomatitis, alveolar osteitis, periodontitis.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Bioallied Sci. 2015 Apr ;7(Suppl 1):S255-9. PMID: 26015726
Article Published Date : Mar 31, 2015
Study Type : Review
Additional Links
Substances : Aloe Vera
Diseases : Gingivitis, Lichen Planus, Oral Submucous Fibrosis, Periodontal Diseases, Radiation Induced Illness: Mucositis, Stomatitis: Aphthous
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Immunomodulatory, Radioprotective
Additional Keywords : Aloe Barbadensis
[+]

Baicalein induces apoptosis and reduces inflammation in LPS-stimulated keratinocytes.Dec 31, 2015

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2016 ;62(7):55-60. Epub 2016 Jun 30. PMID: 27453273
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Baicalein
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oral Lichen Planus
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, NF-kappaB Inhibitor
[+]

Benefits of turmeric supplementation for skin health in chronic diseases.Jul 26, 2020

Pubmed Data : Crit Rev Food Sci Nutr. 2020 Jul 27:1-15. Epub 2020 Jul 27. PMID: 32713186
Article Published Date : Jul 26, 2020
Study Type : Review
Additional Links
Substances : Turmeric
Diseases : Oral Lichen Planus, Pruritus, Psoriasis, Skin Cancer, Skin Diseases
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Effect of photobiomodulation on atrophic-erosive clinical forms of oral lichen planus.Nov 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dent J (Basel). 2022 Nov 27 ;10(12). Epub 2022 Nov 27. PMID: 36547037
Article Published Date : Nov 26, 2022
Study Type : Review
Additional Links
Diseases : Oral Lichen Planus
Therapeutic Actions : Photobiomodulation
[+]

Low-level laser therapy in the treatment of recurrent aphthous stomatitis and oral lichen planus.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Postepy Dermatol Alergol. 2020 Aug ;37(4):475-481. Epub 2020 Sep 2. PMID: 32994766
Article Published Date : Jul 31, 2020
Study Type : Review
Additional Links
Diseases : Oral Lichen Planus, Stomatitis: Aphthous
Therapeutic Actions : Photobiomodulation
[+]

Most studies showed statistically significant result demonstrating the effectiveness of Aloe vera in treatment of oral diseases.Jul 31, 2016

Pubmed Data : J Clin Diagn Res. 2016 Aug ;10(8):ZE01-7. Epub 2016 Aug 1. PMID: 27656587
Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Aloe Vera
Diseases : Burning Mouth Syndrome, Oral Lichen Planus, Oral Mucositis, Oral Submucous Fibrosis, Radiation Induced Illness: Mucositis
[+]

Paeoniflorin drives the immunomodulatory effects of mesenchymal stem cells by regulating Th1/Th2 cytokines in oral lichen planus.Nov 03, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2022 Nov 4 ;12(1):18678. Epub 2022 Nov 4. PMID: 36333421
Article Published Date : Nov 03, 2022
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Oral Lichen Planus
Pharmacological Actions : Immunomodulatory
Additional Keywords : Mesenchymal Stem Cells
[+]

Probiotics as potential biological immunomodulators in the management of oral lichen planus.Mar 22, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Mar 23 ;23(7). Epub 2022 Mar 23. PMID: 35408849
Article Published Date : Mar 22, 2022
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Oral Lichen Planus
Pharmacological Actions : Immunomodulatory, NF-kappaB Inhibitor
[+]

Reveals of quercetin's therapeutic effects on oral lichen planus based on network pharmacology approach and experimental validation.Jan 20, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2022 Jan 21 ;12(1):1162. Epub 2022 Jan 21. PMID: 35064144
Article Published Date : Jan 20, 2022
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Oral Lichen Planus
Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Interleukin-6 Downregulation
[+]

There is early evidence that turmeric/curcumin products and supplements, both oral and topical, may provide therapeutic benefits for skin health.May 22, 2016

Pubmed Data : Phytother Res. 2016 May 23. Epub 2016 May 23. PMID: 27213821
Article Published Date : May 22, 2016
Study Type : Review
Additional Links
Substances : Curcumin, Turmeric
Diseases : Acne, Alopecia, Atopic Dermatitis, Oral Lichen Planus, Pruritus, Psoriasis, Radiodermatitis, Vitiligo
[+]

Total glucosides of paeony improves the immunomodulatory capacity of mesenchymal stem cells.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:151-158. Epub 2018 May 29. PMID: 29852392
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Peony
Diseases : Oral Lichen Planus
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-6 Downregulation, MicroRNA modulator
Additional Keywords : Mesenchymal Stem Cells
[+]

Total glucosides of paeony inhibits the production of inflammatory cytokines in oral lichen planusJun 30, 2016

Pubmed Data : Int Immunopharmacol. 2016 Jul ;36:67-72. Epub 2016 Apr 22. PMID: 27107800
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Peony
Diseases : Lipopolysaccharide-Induced Toxicity, Oral Lichen Planus
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts

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