Oral Mucositis

Name	AC	CK
Curcumin	5	51
Bee Propolis	3	40
Chamomile	4	31
Honey	4	31
Aloe Vera	3	21
Glutamine	1	20
Mulberry	2	20
Probiotics	1	20
Melatonin	2	12
Amla Fruit	1	10
Indigo Naturalis	1	10
Iodine	1	10
Olive	1	10
Sodium Bicarbonate	1	10
Turmeric	1	10
Yarrow	1	10
Zinc	1	10
Cannabidiol	4	7
Alpha-Lipoic Acid	1	2
Eucalyptus	1	2
Guava	1	2
Nattokinase	1	2
Nigella sativa (aka Black Seed)	1	2
Quercetin	1	2
Salvia miltiorrhiza	1	2
Sea buckthorn	1	2

Name	AC	CK	Focus
Methotrexate	1	10
Dioxins	1	1

Name	AC	CK
Photobiomodulation	111	949
Cryotherapy	9	93
Photodynamic therapy	6	81
Light-Emitting Diodes (LEDs) Therapy	2	12
Infrared Light	1	10
Intravascular Laser Blood Irradiation	1	10
Light Therapy: Red Colored	1	10
Ozone Therapy	1	2
Light Therapy: Colored	1	1

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A systematic review and meta-analysis of the effect of low-level laser therapy (LLLT) on chemotherapy-induced oral mucositis.Dec 31, 2017

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Pubmed Data : Eur J Pediatr. 2018 Jan ;177(1):7-17. Epub 2017 Nov 11. PMID: 29128883

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicina (Kaunas). 2023 Aug 3 ;59(8). Epub 2023 Aug 3. PMID: 37629703

Article Published Date : Aug 02, 2023

Study Type : Meta Analysis, Review

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Diseases : Oral Mucositis

Therapeutic Actions : Photobiomodulation

Additional Keywords : Hematopoietic Stem Cells

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Low-level laser therapy in the prevention and treatment of cancer therapy-induced mucositis.Jun 30, 2012

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Pubmed Data : Curr Opin Oncol. 2012 Jul ;24(4):363-70. PMID: 22450151

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Support Care Cancer. 2023 Oct 19 ;31(12):645. Epub 2023 Oct 19. PMID: 37853254

Article Published Date : Oct 18, 2023

Study Type : Meta Analysis, Review

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Diseases : Oral Mucositis

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Chemoprotective Agents, Chemotherapeutic

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Photodynamic therapy for oral mucositis in cancer patients- a systematic review and meta-analysis.Nov 30, 2024

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Pubmed Data : Photodiagnosis Photodyn Ther. 2024 Dec ;50:104424. Epub 2024 Nov 28. PMID: 39615560

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Pubmed Data : Nutr Cancer. 2021 ;73(5):740-749. Epub 2020 Jun 9. PMID: 32515617

Article Published Date : Dec 31, 2020

Study Type : Meta Analysis

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Substances : Curcumin

Diseases : Head and Neck Cancer, Oral Mucositis

Pharmacological Actions : Chemoprotective Agents, Radioprotective

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Laser therapy in the control of oral mucositis: a meta-analysis.Dec 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Oral Oncol. 2011 Feb ;47(2):125-30. Epub 2010 Dec 16. PMID: 21163686

Article Published Date : Jan 31, 2011

Study Type : Human Study

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Diseases : Oral Mucositis

Therapeutic Actions : Photobiomodulation

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A. millefolium distillate healed oral mucositis much more than the routine solution in this study.May 31, 2015

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Pubmed Data : Eur J Oncol Nurs. 2015 Jun ;19(3):207-13. Epub 2015 Feb 7. PMID: 25667123

Article Published Date : May 31, 2015

Study Type : Human Study

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Substances : Yarrow

Diseases : Chemotherapy and Radiation Toxicity, Oral Mucositis

Pharmacological Actions : Chemoprotective Agents

Additional Keywords : Mouthwash, Phytotherapy

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Adherence of head and neck cancer patients to laser photobiomodulation in a public health service.Apr 30, 2021

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Effect of laser phototherapy in the prevention and treatment of chemo-induced mucositis in hamsters.Dec 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Published Date : Oct 31, 2021

Study Type : Human Study

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Diseases : Oral Mucositis

Therapeutic Actions : Photobiomodulation

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Long-term survival of cancer patients after photobiomodulation therapy for prevention and treatment of oral mucositis.Jul 31, 2024

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Pubmed Data : Photodiagnosis Photodyn Ther. 2024 Aug ;48:104248. Epub 2024 Jun 27. PMID: 38944404

Low-level laser therapy in the management of oral mucositis induced by radiotherapy.Dec 31, 2021

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Pubmed Data : J Contemp Dent Pract. 2022 Jan 1 ;23(1):31-36. Epub 2022 Jan 1. PMID: 35656654

Article Published Date : Dec 31, 2021

Study Type : Human Study

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Diseases : Head and Neck Cancer, Oral Mucositis, Radiotherapy

Therapeutic Actions : Infrared Light, Light Therapy: Red Colored, Photobiomodulation

Pharmacological Actions : Radioprotective

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Low-level laser therapy may be useful to improve the symptoms of chemotherapy-induced oral mucositis.Dec 31, 2018

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Patterns of oral mucositis in advanced oral squamous cell carcinoma patients managed with prophylactic photobiomodulation therapy.Feb 28, 2021

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Pubmed Data : Lasers Med Sci. 2021 Mar ;36(2):429-436. Epub 2020 Jul 5. PMID: 32627112

Article Published Date : Feb 28, 2021

Study Type : Human Study

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Diseases : Oral Cancer, Oral Mucositis, Squamous cell carcinoma

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Analgesics, Chemotherapeutic

Additional Keywords : Medication Reduction

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PBM may have a role in decreasing complications related to RT and CRT for HNC, mainly mucositis severity.Dec 31, 2022

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Pubmed Data : Lasers Med Sci. 2023 Apr 15 ;38(1):101. Epub 2023 Apr 15. PMID: 37060370

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Pubmed Data : Photomed Laser Surg. 2015 Nov ;33(11):540-6. Epub 2015 Oct 26. PMID: 26501372

Article Published Date : Oct 31, 2015

Study Type : Human Study

Additional Links

Diseases : Oral Mucositis

Therapeutic Actions : Photobiomodulation

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Preventive versus curative photobiomodulation for oral mucositis in patients with multiple myeloma undergoing hematopoietic stem cell transplantation.Mar 04, 2024

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Pubmed Data : BMJ Support Palliat Care. 2022 Dec ;12(e6):e838-e845. Epub 2019 Sep 16. PMID: 31527154

Article Published Date : Nov 30, 2022

Study Type : Human Study

Additional Links

Diseases : Oral Mucositis, Radiotherapy, Squamous cell carcinoma

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Radioprotective

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Supportive care of cancer patients with a self-applied photobiomodulation device.Jul 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pharmacological Actions : Radioprotective

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Pubmed Data : Int J Mol Sci. 2022 Dec 9 ;23(24). Epub 2022 Dec 9. PMID: 36555260

Article Published Date : Dec 08, 2022

Study Type : Animal Study

Additional Links

Diseases : Chemotherapy and Radiation Toxicity, Oral Mucositis

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Chemotherapeutic

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Effect of class IV laser therapy on chemotherapy-induced oral mucositis.Nov 30, 2013

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Pubmed Data : Am J Pathol. 2013 Dec ;183(6):1747-1757. Epub 2013 Oct 3. PMID: 24096076

Article Published Date : Nov 30, 2013

Study Type : Animal Study

Additional Links

Diseases : Chemotherapy and Radiation Toxicity, Oral Mucositis

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic

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Investigation of the protective effect of Nigella sativa oil in cisplatin induced oral mucositis.Feb 29, 2020

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Pubmed Data : Turk Arch Otorhinolaryngol. 2020 Mar ;58(1):10-15. Epub 2019 Sep 2. PMID: 32313889

Article Published Date : Feb 29, 2020

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Oral Mucositis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents

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Nattokinase crude extract enhances oral mucositis healing.Oct 29, 2021

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PBM reduced the incidence of more severe grade of OM induced by chemoradiotherapy.Aug 31, 2023

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Pubmed Data : Gen Dent. 2022 ;70(2):22-26. PMID: 35225799

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View the Evidence: 162 Abstracts with Oral Mucositis Research

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A systematic review and meta-analysis of the effect of low-level laser therapy (LLLT) on chemotherapy-induced oral mucositis.Dec 31, 2017

Effectiveness of low level laser therapy versus cryotherapy in cancer patients with oral mucositis.Mar 31, 2021

Efficacy of photobiomodulation therapy in the management of oral mucositis in patients with head and neck cancer.Mar 31, 2024

Low-level laser therapy for the treatment of oral mucositis induced by hematopoietic stem cell transplantation.Aug 02, 2023

Low-level laser therapy in the prevention and treatment of cancer therapy-induced mucositis.Jun 30, 2012

Low-level laser therapy in the prevention and treatment of oral mucositis.Sep 30, 2020

Photobiomodulation in oral mucositis in patients with head and neck cancer.Nov 30, 2020

Photobiomodulation was effective in the treatment of oral mucositis.Oct 18, 2023

Photodynamic therapy for oral mucositis in cancer patients- a systematic review and meta-analysis.Nov 30, 2024

A systematic review and meta-analysis of the effect of photodynamic therapy for the treatment of oral mucositis.Apr 29, 2021

Cryotherapy could be a viable intervention that can significantly reduce the occurrence of severe oral mucositis.Sep 30, 2019

Curcumin is a safe, natural bioactive substance that can effectively prevent and treat oral mucositis.Dec 31, 2020

Laser therapy in the control of oral mucositis: a meta-analysis.Dec 31, 2012

Laser therapy was effective in preventing oral mucositis from the 15th to the 45th days of chemoradiotherapy.Feb 12, 2020

Probiotics may reduce the incidence and mitigate the severity of cancer therapy-induced oral mucositis.Jan 06, 2020

Propolis mouthwash is effective and safe in the treatment of severe oral mucositis.Nov 30, 2018

Role of glutamine in the management of oral mucositis in patients with cancer.Feb 18, 2021

A randomized controlled trial of visible-light therapy for the prevention of oral mucositis.Jan 31, 2011

A. millefolium distillate healed oral mucositis much more than the routine solution in this study.May 31, 2015

Adherence of head and neck cancer patients to laser photobiomodulation in a public health service.Apr 30, 2021

Adjunctive oral cryotherapy is effective for the prophylaxis and relief of oral mucositis and anorexia caused by chemotherapy.Dec 31, 2018

Aloe vera on the prevention and treatment of radiotherapy-induced oral mucositis in patients with head-and-neck cancer.Dec 31, 2023

applying natural honey on oral mucositis was effective among head and neck cancers patients receiving external beam radiation therapy.Dec 31, 2015

Both standard care and LLLT treatment improve the grade and pain of OM. Dec 31, 2021

Chamomile infusion cryotherapy to prevent oral mucositis induced by chemotherapy.Jan 09, 2016

Chemotherapy-induced oral mucositis is associated with detrimental bacterial dysbiosis.Apr 24, 2019

Clinical evaluation of intravascular blood irradiation with laser, photobiomodulation, and photodynamic therapy in cancer patients with mucositis.Oct 31, 2021

Clinical use of photobiomodulation for the prevention and treatment of oral mucositis.Jul 20, 2023

Conclusions: Daily delivery of external PBT and completion of OM evaluations is feasible in children undergoing HCT.Mar 31, 2016

Cost-effectiveness of low-level laser therapy (LLLT) in head and neck cancer patients receiving concurrent chemoradiation.Dec 31, 2015

Curcumin could result in faster recovery in comparison with mucosamin and chlorhexidine.May 01, 2022

Effect of laser phototherapy in the prevention and treatment of chemo-induced mucositis in hamsters.Dec 31, 2012

Effect of low level laser therapy in the reduction of oral complications in patients with cancer of the head and neck submitted to radiotherapy.Dec 31, 2012

Effect of low-level laser therapy on inflammatory mediator release during chemotherapy-induced oral mucositis.Dec 31, 2014

Effect of low-level laser therapy on patient reported measures of oral mucositis and quality of life in head and neck cancer patients.Apr 30, 2013

Effectiveness of black mulberry molasses in prevention of radiotherapy-induced oral mucositis.Nov 30, 2017

Effectiveness of curcumin mouthwash on radiation-induced oral mucositis among head and neck cancer patients.Dec 31, 2019

Effectiveness of photobiomodulation on treatment of oral mucositis.Feb 28, 2025

Efficacy of Aloe-Vera use for prevention of chemotherapy-induced oral mucositis.Feb 28, 2021

Efficacy of cryotherapy associated with laser therapy for decreasing severity of melphalan-induced oral mucositis.Aug 31, 2015

Efficacy of low-level laser therapy as an auxiliary tool for management of acute side effects of head and neck radiotherapy.Mar 31, 2018

Efficacy of low-level laser therapy for oral mucositis in hematologic patients undergoing transplantation.Nov 12, 2023

Evaluation of the effect of low level laser on prevention of chemotherapy-induced mucositis.Apr 05, 2013

Expression and degranulation of mast cells in laser photobiomodulated mucositis chemo-induced.Jan 02, 2023

High-power laser photobiomodulation therapy for immediate pain relief of refractory oral mucositis.May 18, 2023

Honey prevents oral mocositis in children undergoing chemotherapy, and also accelerates recovery.Nov 30, 2016

Intraoral versus extraoral photobiomodulation therapy in the prevention of oral mucositis in HSCT patients.Oct 31, 2021

Laser and photochemotherapy for the treatment of oral mucositis in young patients.May 31, 2017

Laser therapy as a preventive approach for oral mucositis in cancer patients undergoing chemotherapy.Sep 30, 2021

Laser therapy in the prevention and treatment of mucositis caused by anticancer chemotherapy.Dec 31, 1991

LLLT was effective in reducing the severity of chemoradiotherapy-induced OM.Mar 31, 2015

Long-term safety of photobiomodulation therapy for oral mucositis in hematopoietic cell transplantation patients.Oct 31, 2021

Long-term survival of cancer patients after photobiomodulation therapy for prevention and treatment of oral mucositis.Jul 31, 2024

Low energy Helium-Neon laser in the prevention of oral mucositis in patients undergoing bone marrow transplant.Jun 30, 1997

Low level laser therapy for concurrent chemoradiotherapy induced oral mucositis in head and neck cancer patients.Aug 31, 2012

Low-level laser in prevention and treatment of oral mucositis in pediatric patients with acute lymphoblastic leukemia.Nov 30, 2013

Low-level laser therapy for treatment of chemotherapy-induced oral mucositis in childhood.Jul 31, 2016

Low-level laser therapy has been shown to be an essential therapy in the prevention and treatment of oral mucositis.Apr 23, 2018

Low-level laser therapy in the management of oral mucositis induced by radiotherapy.Dec 31, 2021

Low-level laser therapy may be useful to improve the symptoms of chemotherapy-induced oral mucositis.Dec 31, 2018

Low-level laser therapy prevents severe oral mucositis in patients submitted to hematopoietic stem cell transplantation.Feb 29, 2016

Low-level laser therapy was clinically effective in reducing the severity of chemotherapy-induced oral mucositis. Jun 30, 2015

New photobiomodulation device for prevention and cure of radiotherapy-induced oral mucositis and dermatitis.Jan 31, 2022

New photobiomodulation protocol prevents oral mucositis in hematopoietic stem cell transplantation recipients-a retrospective study.Nov 30, 2017

Non-thermal CO2 laser therapy (NTCLT): A novel photobiomodulative approach for immediate pain relief of patchy oral mucositis.Dec 31, 2022

Oral care with black mulberry syrup accelerates mucositis healing and alleviates mucositis-related symptoms.Jan 07, 2021

Oral care with propolis as mouthwash for patients undergoing chemotherapy is an effective intervention to improve oral health.Dec 31, 2015

Oral cryotherapy prevents oral mucositis and pain among patients with colorectal cancer undergoing chemotherapy.Dec 31, 2017

Oral cryotherapy was effective for reducing oral mucositis, reactive oxygen series, and inflammatory cytokines in patients undergoing chemotherapy.Mar 31, 2019

Oral mucositis in pediatric patients undergoing hematopoietic stem cell transplantation.Apr 30, 2015

Patients receiving the herbal mouthwash experienced less complications and symptoms associated with oral mucositis.Nov 30, 2016

Patterns of oral mucositis in advanced oral squamous cell carcinoma patients managed with prophylactic photobiomodulation therapy.Feb 28, 2021

Oral Mucositis

View the Evidence:
162 Abstracts with Oral Mucositis Research