Osteopenia

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44 Substances Researched for Osteopenia
NameACCKFocus
Genistein636Locked
Vitamin K423Locked
Ipriflavone120Locked
Plum314Locked
Soy Protein 212Locked
Vitamin E212Locked
Vitamin K2: Menaquinone-7212Locked
Alpha Ketoglutarate110Locked
Black Tea110Locked
Fermented Foods and Beverages110Locked
Ginseng110Locked
Ginsenosides110Locked
Green Tea110Locked
Melatonin110Locked
Natto 110Locked
Oyster Mushroom110Locked
Polyphenols110Locked
Prune110Locked
Reishi Mushroom110Locked
Silica: Orthosilicic acid110Locked
Tocotrienols110Locked
Vitamin D110Locked
phytoestrogens110Locked
Catechin 15Locked
Tea15Locked
Cissus quadrangularis24Locked
FOS (Fructooligosaccharides)24Locked
Xylitol24Locked
Arginine12Locked
Astaxanthin12Locked
Cryptoxanthin22Locked
Curcumin12Locked
Equol12Locked
Guava12Locked
Horse Chestnut12Locked
Isoflavones12Locked
Nicotinamide Mononucleotide12Locked
Nigella sativa (aka Black Seed)12Locked
Soy12Locked
Vitamin E: Gamma-tocotrienol12Locked
Cinnamon11Locked
Fruit: All11Locked
Walnut11Locked
Zinc11Locked
11 Problem Substances Researched for Osteopenia
NameACCKFocus
Bumex110Locked
Diuretic Drugs110Locked
Diuretic: Loop110Locked
Sugar Sweetened Beverages110Locked
Rosiglitazone (trade name Avandia)24Locked
Wheat13Locked
Alendronate (trade name Fosamax) 11Locked
Bisphosphonates11Locked
Ibandronate11Locked
Risedronate11Locked
Zoledronic Acid11Locked
4 Therapeutic Actions Researched for Osteopenia
NameACCKFocus
Whole-Body Vibration 120Locked
Exercise110Locked
Pulsed EMF field (PEMF)110Locked
Tai Chi110Locked
2 Problematic Actions Researched for Osteopenia
NameACCKFocus
DXA Scans220Locked
Radiotherapy110Locked

View the Evidence:
61 Abstracts with Osteopenia Research

[+]

The efficacy and safety of ipriflavone in postmenopausal women with osteopenia or osteoporosis.Dec 31, 2019

Pubmed Data : Pharmacol Res. 2020 09 ;159:104860. Epub 2020 May 12. PMID: 32407952
Article Published Date : Dec 31, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Ipriflavone
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Whole body vibration treatments in elderly women can reduce bone mineral density decline.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(12):e0166774. Epub 2016 Dec 1. PMID: 27907000
Article Published Date : Dec 31, 2015
Study Type : Meta Analysis
Additional Links
Diseases : Osteopenia, Osteoporosis: Age-Related
Therapeutic Actions : Whole-Body Vibration
Additional Keywords : Menopause, mineral density, Osteopenia, Osteoporosis: Age-Related, Risk Reduction, whole-body vibration, women's health
[+]

Alpha-ketoglutarate has some effect on improving lumbar spine bone mineral density in women with osteopenia.Mar 01, 2007

Pubmed Data : Int J Vitam Nutr Res. 2007 Mar;77(2):89-97 PMID: 17896582
Article Published Date : Mar 01, 2007
Study Type : Human Study
Additional Links
Substances : Alpha Ketoglutarate
Diseases : Osteopenia
[+]

Daily consumption of 100 g dried plum for 12 months has modest bone-protective effects in men.Dec 31, 2021

Pubmed Data : J Med Food. 2022 Jan ;25(1):40-47. Epub 2021 Oct 29. PMID: 34714130
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Prune
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

DXA-generated Z-scores and T-scores may differ substantially and significantly in young adults.Oct 01, 2007

Pubmed Data : J Clin Densitom. 2007 Oct-Dec;10(4):351-8. Epub 2007 Jul 26. PMID: 17662630
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Additional Keywords : T-Score/Z-Score Mythology
Anti Therapeutic Actions : DXA Scans
[+]

Effect of ginseng extracts on the improvement of osteopathic and arthritis symptoms in women with osteopenia.Sep 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Sep 24 ;13(10). Epub 2021 Sep 24. PMID: 34684351
Article Published Date : Sep 23, 2021
Study Type : Human Study
Additional Links
Substances : Ginseng, Ginsenosides
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
[+]

Fermentation of Pleurotus ostreatus and Ganoderma lucidum mushrooms and their extracts by the gut microbiota of healthy and osteopenic women.Jan 31, 2021

Pubmed Data : Food Funct. 2021 Feb 1. Epub 2021 Feb 1. PMID: 33521800
Article Published Date : Jan 31, 2021
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Fermented Foods and Beverages, Oyster Mushroom, Reishi Mushroom
Diseases : Osteopenia
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

Genistein compares favorably to HRT in supporting bone health in early postmenopausal women.Oct 01, 2002

Pubmed Data : J Bone Miner Res. 2002 Oct;17(10):1904-12. PMID: 12369794
Article Published Date : Oct 01, 2002
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Osteopenia, Osteoporosis, Postmenopausal Disorders
Additional Keywords : HRT Alternatives, Natural Substances Versus Drugs
[+]

Genistein has favorable effects on some predictors of cardiovascular risk in osteopenic, postmenopausal women.Jan 18, 2010

Pubmed Data : Exp Gerontol. 2010 Jan 18. Epub 2010 Jan 18. PMID: 17682090
Article Published Date : Jan 18, 2010
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Cardiovascular Diseases, Osteopenia, Postmenopausal Disorders
Pharmacological Actions : Vascular Cell Adhesion Molecule-1 Inhibitor
[+]

Genistein is safe and effective in improving bone density without adverse responses in breast density or endometrium thickness in osteopenic, postmenopausal women. Dec 01, 2008

Pubmed Data : J Clin Endocrinol Metab. 2008 Dec;93(12):4787-96. Epub 2008 Sep 16. PMID: 18796517
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Osteopenia, Osteoporosis
[+]

Group exercise has a positive effect on postmenopausal osteoporosis and osteopenia.Aug 01, 2009

Pubmed Data : Acta Orthop Traumatol Turc. 2009 Aug-Oct;43(4):343-50. PMID: 19809232
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Therapeutic Actions : Exercise
[+]

High consumption of sugar-sweetened beverages Is associated with low bone mineral density in young people.Jan 08, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Jan 9 ;15(2). Epub 2023 Jan 9. PMID: 36678194
Article Published Date : Jan 08, 2023
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, High Sugar Diet, Osteopenia, Osteoporosis
Additional Keywords : Risk Factors
Problem Substances : Sugar Sweetened Beverages
[+]

In a healthy middle aged population with normal BMD, an increase in plant food consumption, either alone or in combination with a diet containing meat, is associated with improved bone mineralisation markers.Jan 01, 2020

Pubmed Data : J Nutr Health Aging. 2020 ;24(4):388-397. PMID: 32242206
Article Published Date : Jan 01, 2020
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
[+]

one-year treatment with melatonin increased bone mineral density at femoral neck in a dose-dependent manner, while high dose melatonin increased vBMD in the spine.Jun 02, 2015

Pubmed Data : J Pineal Res. 2015 Jun 3. Epub 2015 Jun 3. PMID: 26036434
Article Published Date : Jun 02, 2015
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Bone Fractures, Osteopenia, Osteoporosis
Pharmacological Actions : Osteogenic
Additional Keywords : Dose Response, Significant Treatment Outcome
[+]

Orthosilicic acid has therapeutic value in the treatment of osteopenia and osteoporosis. Jun 11, 2008

Pubmed Data : BMC Musculoskelet Disord. 2008 Jun 11;9:85. PMID: 18547426
Article Published Date : Jun 11, 2008
Study Type : Human Study
Additional Links
Substances : Silica: Orthosilicic acid
Diseases : Osteopenia, Osteoporosis
[+]

Patients with Gaucher disease living in England have a high frequency of vitamin D deficiency Mar 01, 2009

Pubmed Data : Mol Genet Metab. 2009 Mar ;96(3):113-20. Epub 2009 Jan 14. PMID: 19147383
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Gaucher Disease, Osteopenia, Osteoporosis, Vitamin D Deficiency
Additional Keywords : Bone Density, Lysosomal Storage Disorder
[+]

Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats.Jan 01, 2000

Pubmed Data : J Bone Miner Metab. 2000;18(2):71-6. PMID: 10701161
Article Published Date : Jan 01, 2000
Study Type : Human Study
Additional Links
Substances : Natto , Vitamin K
Diseases : Osteopenia, Osteoporosis
[+]

Prunes preserve hip bone mineral density in a 12-month randomized controlled trial.Oct 05, 2022

Pubmed Data : Am J Clin Nutr. 2022 Oct 6 ;116(4):897-910. PMID: 35798020
Article Published Date : Oct 05, 2022
Study Type : Human Study
Additional Links
Diseases : Hip Fracture, Osteopenia, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

Pulsed electromagnetic field is an effective physiotherapy in postmenopausal women.Dec 31, 2017

Pubmed Data : J Comput Assist Tomogr. 2018 ;42(5):792-797. PMID: 29901507
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Osteopenia
Therapeutic Actions : Pulsed EMF field (PEMF)
[+]

Radiotherapy may result in a wide range of destructive effects in the skeletal system. Sep 01, 1998

Pubmed Data : Radiographics. 1998 Sep-Oct;18(5):1125-36; quiz 1242-3. PMID: 9747611
Article Published Date : Sep 01, 1998
Study Type : Human Study
Additional Links
Diseases : Bone Cancer, Osteopenia
Additional Keywords : Radiation-Induced High Bone Density
Anti Therapeutic Actions : Radiotherapy
[+]

Soy phytoestrogen has a positive effect on bone turnover indicators in menopausal women with osteopenia. Dec 01, 1999

Pubmed Data : Hum Cell. 1999 Dec;12(4):189-96. PMID: 16255781
Article Published Date : Dec 01, 1999
Study Type : Human Study
Additional Links
Substances : phytoestrogens, Soy Protein
Diseases : Osteopenia, Osteoporosis, Postmenopausal Disorders
Pharmacological Actions : Insulin-Like Growth Factor Inhibition/Downregulation
[+]

Supplementation with 150 mg/day Oligopin® for 12 weeks exerts beneficial effects in postmenopausal osteopenia.Dec 31, 2020

Pubmed Data : Phytomedicine. 2021 Jan ;81:153417. Epub 2020 Nov 19. PMID: 33250314
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Polyphenols
Diseases : Osteopenia, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Tai Chi has a beneficial effect on bone formation and bone resorption in breast cancer survivors.Jun 01, 2010

Pubmed Data : Clin Breast Cancer. 2010 Jun;10(3):224-9. PMID: 20497921
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Diseases : Breast Cancer: Recovery , Osteopenia, Osteoporosis
Therapeutic Actions : Tai Chi
[+]

Tea drinking is associated with preservation of hip structure in elderly women. Mar 01, 1996

Pubmed Data : J Pediatr Endocrinol Metab. 1996 Mar;9 Suppl 1:101-11. PMID: 17921409
Article Published Date : Mar 01, 1996
Study Type : Human Study
Additional Links
Substances : Black Tea, Green Tea
Diseases : Hip Fracture, Osteopenia, Osteoporosis
[+]

The majority of those patients who will sustain a low-trauma fracture do not meet the T-score definition of osteoporosis. Conversely, younger individuals with BD in the osteoporotic range but no other risk factors have relatively low rates of fracture.Mar 01, 2012

Pubmed Data : Curr Osteoporos Rep. 2012 Mar ;10(1):28-41. PMID: 22274642
Article Published Date : Mar 01, 2012
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Osteopenia, Osteoporosis
Additional Keywords : T-Score/Z-Score Mythology
[+]

These results confirm the ability of dried plum to prevent the loss of total body BMD in older osteopenic postmenopausal women.Feb 21, 2016

Pubmed Data : Osteoporos Int. 2016 Feb 22. Epub 2016 Feb 22. PMID: 26902092
Article Published Date : Feb 21, 2016
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteopenia, Osteoporosis
[+]

Thirty-nine percent of Hologic (Hologic, Inc., Bedford, MA) subjects and 30% of Lunar (GE Lunar, GE Madison, WI) subjects diagnosed with "osteoporosis" by T-score were reclassified as either "normal" or "osteopenia" when their Z-score was used.Jan 01, 2009

Pubmed Data : J Clin Densitom. 2009 Jan-Mar;12(1):11-6. PMID: 19195620
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Additional Keywords : T-Score/Z-Score Mythology
Anti Therapeutic Actions : DXA Scans
[+]

Treatment with loop diuretics affects bone turnover and decreases bone mineral density.Jan 01, 2006

Pubmed Data : J Bone Miner Res. 2006 Jan;21(1):163-70. Epub 2005 Oct 10. PMID: 16355285
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Problem Substances : Bumex, Diuretic: Loop, Diuretic Drugs
[+]

Twelve-week annatto-extracted tocotrienol supplementation decreased bone resorption and improved bone turnover rate via suppressing bone remodeling regulators in postmenopausal women with osteopenia.Jan 01, 2018

Pubmed Data : Osteoporos Int. 2018 04 ;29(4):881-891. Epub 2018 Jan 12. PMID: 29330573
Article Published Date : Jan 01, 2018
Study Type : Human Study
Additional Links
Substances : Tocotrienols
Diseases : Osteopenia, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Vitamin E (mixed-tocopherol) supplementation in postmenopausal osteopenic women may have a preventive effect on bone loss through anti-resorptive activity.Nov 24, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Nov 25 ;13(12). Epub 2021 Nov 25. PMID: 34959779
Article Published Date : Nov 24, 2021
Study Type : Human Study
Additional Links
Substances : Vitamin E
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
[+]

Vitamin K supplementation in postmenopausal women wih osteopenia appears to protect against bone fractures and cancers. Oct 14, 2008

Pubmed Data : PLoS Med. 2008 Oct 14;5(10):e196. PMID: 18922041
Article Published Date : Oct 14, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin K
Diseases : Bone Fractures, Cancers: All, Osteopenia
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

Vitamin MK-7 preserves trabecular bone structure at the tibia.Nov 30, 2016

Pubmed Data : Eur J Endocrinol. 2016 Dec ;175(6):541-549. Epub 2016 Sep 13. PMID: 27625301
Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
[+]

Epigallocatechin-3-gallate enhances the osteoblastogenic differentiation of human adipose-derived stem cells.Jan 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2019 ;13:1311-1321. Epub 2019 Apr 23. PMID: 31114166
Article Published Date : Jan 01, 2019
Study Type : Human In Vitro
Additional Links
Substances : Catechin , Tea
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Regenerative
Additional Keywords : Bone Regeneration
[+]

Celiac disease presenting as severe osteopenia has been reported.Nov 01, 2011

Pubmed Data : Hawaii Med J. 2011 Nov ;70(11):242-4. PMID: 22162604
Article Published Date : Nov 01, 2011
Study Type : Human: Case Report
Additional Links
Diseases : Celiac Disease, Gluten Sensitivity, Osteopenia
Problem Substances : Wheat
[+]

Astaxanthin improves osteopenia caused by aldehyde-stress resulting from Aldh2 mutation due to impaired osteoblastogenesis. Jun 17, 2020

Pubmed Data : Biochem Biophys Res Commun. 2020 Jun 18 ;527(1):270-275. Epub 2020 May 4. PMID: 32446379
Article Published Date : Jun 17, 2020
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Beneficial effect of Cissus quadrangularis Linn. on osteopenia associated with streptozotocin-induced type 1 diabetes mellitus.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharmacol Sci. 2014 ;2014:483051. Epub 2014 Apr 7. PMID: 24803925
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Cissus quadrangularis
Diseases : Diabetes Mellitus: Type 1, Osteopenia
Pharmacological Actions : Osteoprotective
[+]

Curcumin improves bone microarchitecture and enhances mineral density in transgenic mice.Jan 15, 2011

Pubmed Data : Phytomedicine. 2011 Jan 15;18(2-3):205-13. Epub 2010 Jul 16. PMID: 20637579
Article Published Date : Jan 15, 2011
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Bone Fractures, Osteopenia, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dried plum reverses bone loss associated with osteopenia in rats. Nov 01, 2005

Pubmed Data : Menopause. 2005 Nov-Dec;12(6):755-62. Epub 2005 Nov 8. PMID: 16278620
Article Published Date : Nov 01, 2005
Study Type : Animal Study
Additional Links
Substances : Plum
Diseases : Osteopenia
[+]

Effect of Cissus quadrangularis Linn on the development of osteopenia induced by ovariectomy.Dec 31, 2010

Pubmed Data : Clin Ter. 2011 ;162(4):307-12. PMID: 21912817
Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Cissus quadrangularis
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
Additional Keywords : Natural Substances Versus Drugs, Ovariectomy-Induced Changes, Plant Extracts
[+]

Effects of alpha-Escin on mechanical features of the femoral bone in rats with experimental post-steroid osteopenia.Dec 31, 1999

Pubmed Data : Acta Pol Pharm. 2000 ;57(4):317-20. PMID: 11126622
Article Published Date : Dec 31, 1999
Study Type : Animal Study
Additional Links
Substances : Horse Chestnut
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
[+]

Equol and genistein compare favorably with hormone replacement therapy (estradiol) on bone quality in a rat osteopenia model. Dec 09, 2009

Pubmed Data : Phytother Res. 2009 Dec 9. PMID: 20013821
Article Published Date : Dec 09, 2009
Study Type : Animal Study
Additional Links
Substances : Equol, Genistein
Diseases : Osteopenia
Additional Keywords : Natural Substances Versus Drugs
[+]

Genistein is superior to the bone drugs alendronate, raloxifene and estradiol in osteoporotic, ovariectomized rats. Nov 01, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2008 Nov;155(6):896-905. Epub 2008 Aug 11. PMID: 18695641
Article Published Date : Nov 01, 2008
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Bone Fractures, Osteopenia, Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes, Superiority of Natural Substances versus Drugs
[+]

Guava fruit extract and its triterpene constituents have osteoanabolic effect.Mar 07, 2017

Pubmed Data : J Nutr Biochem. 2017 Mar 8 ;44:22-34. Epub 2017 Mar 8. PMID: 28343085
Article Published Date : Mar 07, 2017
Study Type : Animal Study
Additional Links
Substances : Guava
Diseases : Osteopenia
Pharmacological Actions : Osteogenic, Wnt/β-catenin signaling pathway modulation
[+]

L-arginine supplementation normalizes bone turnover and preserves bone mass in streptozotocin-induced diabetic rats.Jun 01, 2009

Pubmed Data : J Endocrinol Invest. 2009 Jun;32(6):546-51. Epub 2009 May 5. PMID: 19494718
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Diabetes Mellitus: Type 1: Prevention, Osteopenia, Osteoporosis
[+]

Menaquinone-7, a form of vitamin K2, has a stimulatory effect on bone formation in the femoral tissues of elderly female rats in vitro.Dec 01, 2002

Pubmed Data : Int J Mol Med. 2002 Dec;10(6):729-33. PMID: 12429999
Article Published Date : Dec 01, 2002
Study Type : Animal Study
Additional Links
Substances : Genistein, Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Aging, Osteopenia, Osteoporosis
[+]

Nicotinamide mononucleotide supplementation mitigates osteopenia induced by modeled microgravity in rats.Jun 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Stress Chaperones. 2023 Jul ;28(4):385-394. Epub 2023 May 17. PMID: 37195399
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Nicotinamide Mononucleotide
Diseases : Osteopenia, Space Flight Associated Adverse Changes
Pharmacological Actions : Antioxidants, Osteoprotective
Additional Keywords : Microgravity Induced Bone Loss
[+]

Nigella Sativa reverses osteoporosis in ovariectomized rats.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2014 ;14(1):22. Epub 2014 Jan 14. PMID: 24422662
Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Menopausal Syndrome, Osteopenia, Osteoporosis, Ovarian Failure
Additional Keywords : Ovariectomy-Induced Changes
[+]

Rosiglitazone causes bone loss in mice by suppressing osteoblast (bone-building cells) differentiation and bone formation.Mar 01, 2005

Pubmed Data : Endocrinology. 2005 Mar;146(3):1226-35. Epub 2004 Dec 9. PMID: 15591153
Article Published Date : Mar 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Aging, Osteopenia, Osteoporosis
Additional Keywords : Accelerated Aging
Problem Substances : Rosiglitazone (trade name Avandia)
[+]

Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone.Jun 01, 2007

Pubmed Data : Endocrinology. 2007 Jun;148(6):2669-80. Epub 2007 Mar 1. PMID: 17332064
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Aging, Osteopenia, Osteoporosis
Additional Keywords : Accelerated Aging
Problem Substances : Rosiglitazone (trade name Avandia)
[+]

Soy isoflavones and omega-3 fatty acids havea protective effect on bone mass in ovariectomized rats.Aug 01, 2005

Pubmed Data : J Nutr Biochem. 2005 Aug;16(8):479-88. PMID: 16043030
Article Published Date : Aug 01, 2005
Study Type : Animal Study
Additional Links
Substances : Isoflavones, Soy
Diseases : Osteopenia
[+]

The combination of FOS and dried plum is capable of reversing ovariectomy induced bone loss. Aug 01, 2009

Pubmed Data : Helicobacter. 2009 Aug;14(4):280-5. PMID: 20132045
Article Published Date : Aug 01, 2009
Study Type : Animal Study
Additional Links
Substances : FOS (Fructooligosaccharides), Plum
Diseases : Osteopenia, Osteoporosis
[+]

The combination of soy and FOS reverse the loss of certain microarchitectural parameters of the bone in osteopenic rats. Jul 01, 2006

Pubmed Data : Menopause. 2006 Jul-Aug;13(4):692-9. PMID: 16837891
Article Published Date : Jul 01, 2006
Study Type : Animal Study
Additional Links
Substances : FOS (Fructooligosaccharides), Soy Protein
Diseases : Osteopenia, Osteoporosis
[+]

Vitamin E, with gamma-tocotrienol, can promote bone formation in normal rats. Feb 10, 2010

Pubmed Data : J Bone Miner Metab. 2010 Feb 10. Epub 2010 Feb 10. PMID: 20145960
Article Published Date : Feb 10, 2010
Study Type : Animal Study
Additional Links
Substances : Vitamin E, Vitamin E: Gamma-tocotrienol
Diseases : Osteopenia, Osteoporosis
[+]

Xylitol improves bone biomechanical properties in xylitol-fed aged ratsJan 01, 2002

Pubmed Data : Metabolism. 2002 Jan;51(1):92-6. PMID: 11782878
Article Published Date : Jan 01, 2002
Study Type : Animal Study
Additional Links
Substances : Xylitol
Diseases : Osteopenia, Osteoporosis
[+]

Xylitol protects against aging-related osteoporotic changes in rats. Nov 01, 2001

Pubmed Data : Gerontology. 2001 Nov-Dec;47(6):300-5. PMID: 11721142
Article Published Date : Nov 01, 2001
Study Type : Animal Study
Additional Links
Substances : Xylitol
Diseases : Osteopenia, Osteoporosis
[+]

Beta-cryptoxanthin in combination with zinc have a unique anabolic effect on bone components. Nov 01, 2005

Pubmed Data : Biol Pharm Bull. 2005 Nov;28(11):2142-5. PMID: 16272706
Article Published Date : Nov 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Cryptoxanthin, Zinc
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Anabolic Agents
Additional Keywords : Natural Substance Synergy
[+]

Beta-cryptoxanthin, which is greatly present in fruits, stimulates bone formation and inhibits bone resorption in tissue culture in vitro.Mar 01, 2004

Pubmed Data : Mol Cell Biochem. 2004 Mar;258(1-2):137-44. PMID: 15030178
Article Published Date : Mar 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Cryptoxanthin, Fruit: All
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Anticarcinogenic Agents
[+]

Bisphosphonates are associated with a wide range of adverse health effects.Apr 01, 2009

Pubmed Data : Hormones (Athens). 2009 Apr-Jun;8(2):96-110. PMID: 19570737
Article Published Date : Apr 01, 2009
Study Type : Review
Additional Links
Diseases : Osteopenia, Osteoporosis
Problem Substances : Alendronate (trade name Fosamax) , Bisphosphonates, Ibandronate, Risedronate, Zoledronic Acid
[+]

Cinnamon bark extract suppresses osteoclastogenesis and inhibits bone resorption. Oct 15, 2008

Pubmed Data : Bioorg Med Chem. 2008 Oct 15;16(20):9176-83. Epub 2008 Sep 14. PMID: 18823786
Article Published Date : Oct 15, 2008
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon
Diseases : Osteopenia, Osteoporosis
[+]

Vitamin K may be effective in preventing and treating osteoporosis and arterial calcification.Aug 01, 2005

Pubmed Data : Am J Health Syst Pharm. 2005 Aug 1;62(15):1574-81. PMID: 16030366
Article Published Date : Aug 01, 2005
Study Type : Review
Additional Links
Substances : Vitamin K
Diseases : Arterial Calcification, Osteopenia, Osteoporosis
Additional Keywords : Calcification Paradox
[+]

Walnut extract (Juglans regia L.) demonstrates anti-inflammatory activity in human aorta endothelial cells and stimulates osteoblastic activity.Apr 01, 2008

Pubmed Data : Br J Nutr. 2008 Apr;99(4):715-22. Epub 2007 Oct 5. PMID: 17916277
Article Published Date : Apr 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Walnut
Diseases : Arteriosclerosis, Cardiovascular Diseases, Osteopenia, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents

Copyright: lightwise / 123RF Stock Photo

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