Pancreatic Cancer

Name	AC	CK
Vitamin C	10	85
Vitamin E	9	75
Curcumin	36	72
Vitamin D	8	65
Nuts	6	52
Mistletoe	5	34
Fruit: All	3	31
Vegetables: All	3	31
Vitamin B-12	2	30
Sulforaphane	17	28
Cruciferous Vegetables	2	25
Ginsenosides	4	25
Alpha-Lipoic Acid	2	20
Cryptoxanthin	1	20
Fiber	1	20
Flavonoids	7	20
Selenium	1	20
beta-Carotene	1	20
Omega-3 Fatty Acids	7	19
Quercetin	15	17
Oridonin	9	16
Resveratrol	14	16
Tocotrienol: Delta	5	15
Apigenin	8	14
EGCG (Epigallocatechin gallate)	11	13
Genistein	11	13
Aloe Vera	2	11
Emodin	7	11
Lycopene	2	11
Tomato	2	11
Beta-glucan	1	10
Burdock	1	10
Carotenoids	1	10
Cholesterol	1	10
Coffee	1	10
EPA (Eicosapentaenoic Acid)	1	10
Fish Oil	1	10
Folate: Dietary	1	10
Folic Acid	1	10
Garlic	1	10
L-Carnitine	1	10
Lentinan	1	10
Magnesium	1	10
Methionine	1	10
Stearic Acid (stearate)	1	10
Thymoquinone	5	9
Ginger	3	8
Naringenin	2	7
Polyphenols	5	7
Spirulina	2	6
Cucurbitacin B	3	5
Dandelion	1	5
Fisetin	5	5
Green Tea	4	5
Indole-3-Carbinol	4	5
Melatonin	4	5
Pterostilbene	4	5
Xanthohumol	4	5
Zerumbone	1	5
Zyflamend	3	5
6-Shogaol	2	4
Artemisinin	3	4
Bee Propolis	4	4
Broccoli	2	4
Cannabinoids	4	4
Capsaicin	2	4
Ellagic Acid	4	4
Pancreatic Enzymes	3	4
Piperlongumine	3	4
Shikonin	2	4
Viruses: Beneficial	4	4
Vitamin C: Intravenous	2	4
Ashwagandha	2	3
Baicalein	2	3
Benzyl isothiocyanate	2	3
Bitter Melon	2	3
Crocin	2	3
Deguelin	3	3
Ginkgo biloba	2	3
Grape Seed Extract	2	3
Nexrutine (Phellodendrom)	3	3
Paeoniflorin	3	3
Seaweed: Brown	2	3
Silibinin	2	3
Tocotrienol: Gamma	3	3
Wheat Germ	3	3
Astaxanthin	1	2
Basil	1	2
Bee Venom	2	2
Berbamine	2	2
Berberine	2	2
Berries: All	2	2
Betulinic acid	2	2
Bitter Apple	1	2
Black Tea	1	2
Boswellia	1	2
Calcium	1	2
Cannabidiol	2	2
Cannabis	2	2
Catechin	2	2
Cayenne	1	2
Citrus Peel	1	2
Cordyceps Militaris	1	2
Cucurbitacin D	2	2
Curcumin: Lipidated	1	2
Deuterium (heavy water)	2	2
Echinacea	2	2
Fermented Foods and Beverages	1	2
Frankincense	1	2
Gingerol	1	2
Gold (nanoparticles)	2	2
Graviola	2	2
Hesperidin	1	2
Honokiol	2	2
Inositol Hexaphosphate	2	2
Isoflavones	2	2
Kaempferol	2	2
Lactoferrin	1	2
Lichens	2	2
Lime: Key	2	2
Long Pepper	1	2
Luteolin	2	2
Mangosteen	1	2
Mimosa pudica	1	2
NAC (N-acetyl-L-cysteine)	2	2
Nigella sativa (aka Black Seed)	2	2
Orthosiphon	1	2
Palm Oil	2	2
Peony	1	2
Phenethyl isothiocyanate	2	2
Piceatannol	1	2
Pomegranate	2	2
Psychedelics:All	1	2
Saffron	2	2
Sea Cucumber	1	2
Seaweed	1	2
Sophora Flavescens	1	2
Sprouts	1	2
Tanshinone IIA	2	2
Triphala	1	2
Acai	1	1
Adlay	1	1
Agaricus Blazei	1	1
Anthocyanins	1	1
Apricot	1	1
Arctigenin	1	1
Arginine	1	1
Asparagus	1	1
Bael	1	1
Banana	1	1
Beet	1	1
Betel	1	1
Biochanin A	1	1
Bisdemethoxycurcumin	1	1
Black Raspberry	1	1
Blackberries	1	1
Blueberry	1	1
Bromelain	1	1
Caffeic acid phenethyl ester	1	1
Cannabinoids: Synthetic	1	1
Carnitine	1	1
Chinese Skullcap	1	1
Chlorogenic Acid	1	1
Chokeberry	1	1
Coptidis rhizoma	1	1
Corn Silk	1	1
Cranberry	1	1
Cucumber	1	1
DHA (Docosahexaenoic Acid)	1	1
DIM (3,3'-diindolylmethane)	1	1
Daidzein	1	1
Damnacanthal	1	1
Dates	1	1
Diosgenin	1	1
Dracaena draco	1	1
Eggplant	1	1
Elderberry	1	1
Ferulic acid	1	1
Feverfew	1	1
Fucoidan	1	1
Garcinia indica	1	1
Geraniol	1	1
Ginseng, unspecified species	1	1
Goji	1	1
Grapes	1	1
Haplophyllum perforatum	1	1
Harmine	1	1
Helenalin	1	1
Horsetail	1	1
Hydroxytyrosol	1	1
Icogenin	1	1
Indian Gooseberry	1	1
Isothiocyanates	1	1
Kimchi	1	1
Kiwifruit	1	1
Lysine	1	1
Moringa oleifera	1	1
Myricetin	1	1
Neem	1	1
Nobiletin	1	1
Noni	1	1
Nordihydroguaiaretic acid (NDGA)	1	1
Oat Bran	1	1
Oleocanthal	1	1
Oleuropein	1	1
Olive leaf extract	1	1
Oxygen Therapies	1	1
Paeonol	1	1
Parthenolide	1	1
Phellinus Linteus	1	1
Poria cocos	1	1
Proline	1	1
Pycnogenol (Pine Bark)	1	1
Raspberry	1	1
Reishi Mushroom	1	1
Rhubarb	1	1
Rice Bran	1	1
Sesame Seeds	1	1
Spinach	1	1
Stevia	1	1
Tocotrienol: Alpha	1	1
Triptolide	1	1
Ume (Japanese apricot)	1	1
Vitamin E: delta-tocopherol	1	1
Vitamin K	1	1
Wasabi	1	1
Watermelon	1	1
Wogonin	1	1
Wormwood	1	1
acetyl-11-keto-beta-boswellic acid	1	1
cottonseed oil (gossypol)	1	1
St. Johns Wort	1	0

Name	AC	CK
Insulin	1	20
Meat	2	20
Proton-Pump Inhibitors	1	20
Fructose	2	11
Dl-alpha-tocopherol acetate	1	10
Foods: High Glycemic Load	1	10
Meat: Cooked	1	10
Statin Drugs	1	10
Sugary soda	1	10
Tobacco: Smoking	1	10
High Fructose Corn Syrup	1	1
Hydrocarbons	1	1
Mineral Oil	1	1
N-Nitrosamines	1	1
Paraffin	1	1
Polycyclic aromatic hydrocarbon	1	1

Name	AC	CK
Sunlight exposure	1	20
Dietary Modification: Low Glycemic Diet	1	10
Integrative Medicine	1	10
Ultrasound therapy	1	10
Dietary Modification: Macrobiotic Diet	1	1
Electric Stimulation	1	1
Ozone Therapy	1	1
Qigong	1	1

Name	AC	CK
Chemotherapy	3	30
Overnutrition	1	2
Western Diet	1	2
Fine Needle Aspiration	1	1

[+]

A high intake of dietary fiber was associated with a reduced risk of pancreatic cancer.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Oncol. 2016 Jun 20. Epub 2016 Jun 20. PMID: 27325858

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : In Vivo. 2009 Jan-Feb;23(1):171-5. PMID: 19368145

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Substances : Aloe Vera

Diseases : Cancer Metastasis, Cancers: All, Colorectal Cancer, Gastric Cancer, Pancreatic Cancer

Additional Keywords : Drug-Plant-Vitamin Synergies

[+]

Alpha lipoic acid may provide an effective adjuvant in the treatment of metastatic and nonmetastatic pancreatic cancer.Dec 01, 2009

Click here to read the entire abstract

Pubmed Data : Integr Cancer Ther. 2009 Dec;8(4):416-22. PMID: 20042414

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2023 Jan 29 ;15(3). Epub 2023 Jan 29. PMID: 36771385

Article Published Date : Jan 28, 2023

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2008 Mar 5;116(2):325-32. Epub 2007 Dec 4. PMID: 18090127

Article Published Date : Mar 05, 2008

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Pancreatic Cancer

Additional Keywords : Risk Reduction

[+]

Combination chemotherapy and chemoradiation does not improve overall survival in inoperabe advanced pancreatic cancer over single chemotherapy alone.Jan 01, 2009

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Pubmed Data : Cochrane Database Syst Rev. 2009(4):CD002093. Epub 2009 Oct 7. PMID: 19821291

Pubmed Data : J Nutr. 2005 Mar;135(3):592-7. PMID: 15735099

Article Published Date : Mar 01, 2005

Study Type : Human Study

Additional Links

Substances : Lycopene, Tomato

Diseases : Pancreatic Cancer

[+]

Dl-alpha-tocopherol acetate supplementation is associated with increased mortality in pancreatic cancer patients. Jul 01, 1999

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Pubmed Data : Cancer. 1999 Jul 1;86(1):37-42. PMID: 10391561

Article Published Date : Jul 01, 1999

Study Type : Human Study

Additional Links

Diseases : Pancreatic Cancer, Smoking

Problem Substances : Dl-alpha-tocopherol acetate

[+]

Efficacy of Lentinula edodes mycelia extract on chemotherapy-related tasted disorders in pancreatic cancer patients.Dec 31, 2022

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Pubmed Data : Nutr Cancer. 2023 ;75(1):236-246. Epub 2022 Aug 11. PMID: 35950537

Article Published Date : Dec 31, 2022

Study Type : Human Study

Additional Links

Substances : Shiitake Mushroom

Diseases : Chemotherapy, Pancreatic Cancer, Taste Disorders

Pharmacological Actions : Chemoprotective Agents

Additional Keywords : Plant Extracts

[+]

Elevated neutrophil to lymphocyte ratio is linked poorer survival in advanced pancreatic cancer. Jul 05, 2010

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Pubmed Data : Biomarkers. 2010 Jul 5. Epub 2010 Jul 5. PMID: 20602543

Article Published Date : Jul 05, 2010

Study Type : Human Study

Additional Links

Diseases : Pancreatic Cancer

[+]

EPA (eicosapentaenoic acid) induces programmed cell death in human pancreatic cancer cells. Oct 01, 2005

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Pubmed Data : Nutrition. 2005 Oct;21(10):1010-7. PMID: 16157238

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Cancer. 2013 Nov 26 ;109(11):2911-6. Epub 2013 Oct 22. PMID: 24149179

Article Published Date : Nov 25, 2013

Study Type : Human Study

Additional Links

Substances : Nuts

Diseases : Pancreatic Cancer

Additional Keywords : Risk Reduction

[+]

High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.Jan 06, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2017 12 7 ;7(1):17188. Epub 2017 Dec 7. PMID: 29215048

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2012 ;11:52. Epub 2012 Jul 23. PMID: 22824168

[+]

Poorly controlled diabetes may be associated with a higher possibility of pancreatic cancer.May 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2016 Jun ;95(24):e3921. PMID: 27311001

Article Published Date : May 31, 2016

Study Type : Human Study

Additional Links

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Pancreatic Cancer

Additional Keywords : Risk Factors

[+]

Pretreatment C-reactive protein level predicts outcome and patterns of failure after chemoradiotherapy for locally advanced pancreatic cancer.Oct 31, 2015

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Pubmed Data : Pancreatology. 2015 Nov-Dec;15(6):694-700. Epub 2015 Oct 14. PMID: 26601881

Article Published Date : Oct 31, 2015

Study Type : Human Study

Additional Links

Diseases : C-Reactive Protein, Pancreatic Cancer

Additional Keywords : Risk Factors

[+]

Red and processed meats may be involved in pancreatic carcinogenesis.Apr 03, 2017

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2098-105. PMID: 16172216

Article Published Date : Sep 01, 2005

Study Type : Human Study

Additional Links

Diseases : Insulin Resistance, Pancreatic Cancer

Additional Keywords : Diseases that are Linked

Problem Substances : Sugary soda

[+]

The effects of self-acupressure on pain, fatigue, and sleep quality in colon and pancreatic cancer patients receiving chemotherapy.Jan 15, 2023

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Pubmed Data : Cancer Nurs. 2023 Jan 16. Epub 2023 Jan 16. PMID: 36728147

Article Published Date : Jan 15, 2023

Study Type : Human Study

Additional Links

Diseases : Cancer: Fatigue, Colon Cancer, Pancreatic Cancer, Sleep Disorders

Therapeutic Actions : Acupressure

Pharmacological Actions : Chemotherapeutic

[+]

The results of this study suggest that HIFU therapy is safe and has the potential to be a new method of combination therapy for unresectable pancreatic cancer.Jul 27, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : World J Gastroenterol. 2014 Jul 28 ;20(28):9570-7. PMID: 25071354

Article Published Date : Jul 27, 2014

Study Type : Human Study

Additional Links

Diseases : Pancreatic Cancer

Therapeutic Actions : Integrative Medicine, Ultrasound therapy

Pharmacological Actions : Analgesics, Chemotherapeutic

Additional Keywords : Significant Treatment Outcome

[+]

These findings provide evidence to support the hypothesis that poor oral hygiene plays an important role in the development of pancreatic cancer.Jul 31, 2015

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Pubmed Data : Int J Cancer. 2015 Aug 1. Epub 2015 Aug 1. PMID: 26235255

Article Published Date : Jul 31, 2015

Study Type : Human Study

Additional Links

Diseases : Dental Plaque, Pancreatic Cancer

Additional Keywords : Increased Risk

[+]

This study provides evidence for a preventive effect of flavonols on pancreatic cancer.Oct 14, 2007

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Am J Epidemiol. 2007 Oct 15 ;166(8):924-31. Epub 2007 Aug 9. PMID: 17690219

Article Published Date : Oct 14, 2007

Study Type : Human Study

Additional Links

Substances : Flavonoids

Diseases : Pancreatic Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Risk Reduction

[+]

Unsaturated fats, and not saturated ones like stearate, may promote pancreatic carcinogenesis. Jul 01, 2009

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Pubmed Data : Thromb Res. 2009 Jul;124(3):328-34. Epub 2009 Apr 5. PMID: 2572741

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Substances : Stearic Acid (stearate)

Diseases : Pancreatic Cancer

[+]

Vitamin C and vitamin E mitigate the risk of pancreatic ductal adenocarcinoma from meat-derived mutagen exposure.May 16, 2019

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Pubmed Data : J Nutr. 2019 May 17. Epub 2019 May 17. PMID: 31100111

Article Published Date : May 16, 2019

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Pubmed Data : EBioMedicine. 2015 Dec ;2(12):1987-95. Epub 2015 Nov 14. PMID: 26844278

Article Published Date : Nov 30, 2015

Study Type : Human Study

Additional Links

Substances : Tocotrienol: Delta, Vitamin E

Diseases : Pancreatic Cancer, Pancreatic Neoplasms

Pharmacological Actions : Apoptotic, Chemopreventive

Additional Keywords : Significant Treatment Outcome

[+]

A diet rich in sulforaphane and related mustard oils may be considered as a supportive nutritional strategy to enhance therapeutic efficacy in patients suffering from pancreatic cancer.Mar 29, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2014 Mar 30 ;5(6):1621-34. PMID: 24742583

Article Published Date : Mar 29, 2014

Study Type : Human In Vitro

Additional Links

Substances : Cruciferous Vegetables, Sulforaphane

Diseases : Cancers: Drug Resistant, Pancreatic Cancer

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemotherapeutic

Additional Keywords : Cancer Stem Cells, Dietary Concentrations

[+]

[+]

Zerumbone was able to induce apoptosis of pancreatic carcinoma cell lines Jan 01, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2012 ;2012:936030. Epub 2012 Jan 29. PMID: 22454691

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Pubmed Data : Anticancer Drugs. 2018 Feb 12. Epub 2018 Feb 12. PMID: 29438178

Article Published Date : Feb 11, 2018

Study Type : Human: Case Report

Additional Links

Substances : Vitamin C: Intravenous

Diseases : Pancreatic Cancer

Pharmacological Actions : Chemopreventive

[+]

Ursolic acid restores sensitivity to gemcitabine.Jan 14, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Surg Res. 2009 May 15. PMID: 19631339

Article Published Date : May 15, 2009

Study Type : Animal Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Pancreatic Cancer

[+]

A ketogenic diet in combination with gemcitabine mitigates pancreatic cancer-associated c.achexia.Jun 27, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Biomed Sci. 2015 ;22(1):28. Epub 2015 Apr 17. PMID: 25898131

Article Published Date : Dec 31, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Polyphenols, Seaweed

Diseases : Cancers: Drug Resistant, Cancers: Radiation-Resistant, Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Autophagy Inhibitors, Chemotherapeutic

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine, Gene Expression Regulation, Significant Treatment Outcome

[+]

Anticancer activity of aqueous fenugreek seed extract against pancreatic cancer, histological evidence.Aug 31, 2021

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Pubmed Data : J Gastrointest Cancer. 2021 Sep 1. Epub 2021 Sep 1. PMID: 34472011

Article Published Date : Aug 31, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Fenugreek

Diseases : Pancreatic Cancer

Pharmacological Actions : Chemotherapeutic

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Res. 2015 Jun 16. Epub 2015 Jun 16. PMID: 26081808

Article Published Date : Jun 15, 2015

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Pancreatic Cancer

Pharmacological Actions : Radioprotective, Radiosensitizer

Additional Keywords : Selective Cytotoxicity

[+]

Astaxanthin inhibits gemcitabine-resistant human pancreatic cancer progressionOct 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2011 ;6(10):e26943. Epub 2011 Oct 31. PMID: 22066019

Article Published Date : Jan 01, 2011

Study Type : Transgenic Animal Study

Additional Links

Substances : Boswellia

Diseases : Cancer Metastasis, Pancreatic Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

[+]

Bromelain and acetylcysteine alone and in combination with gemcitabine inhibit subcutaneous deposits of pancreatic cancer after intraperitoneal injection.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Am J Transl Res. 2021 ;13(12):13524-13539. Epub 2021 Dec 15. PMID: 35035694

Article Published Date : Dec 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bromelain, NAC (N-acetyl-L-cysteine)

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

Capsaicin is an effective inhibitor of in vitro and in vivo growth of pancreatic cancer cells. Dec 01, 2008

Click here to read the entire abstract

Pubmed Data : Cell Cycle. 2022 Jun ;21(12):1249-1266. Epub 2022 Mar 6. PMID: 35253605

Article Published Date : May 31, 2022

Study Type : Animal Study

Additional Links

Substances : Curcumol

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , MicroRNA modulator

[+]

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2011 Nov ;36(22):3167-71. PMID: 22375400

Article Published Date : Nov 01, 2011

Study Type : Animal Study

Additional Links

Substances : Emodin

Diseases : Cancer Metastasis, Pancreatic Cancer, Pancreatic Cancer: Metastatic

Pharmacological Actions : Anti-Angiogenic, Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor

[+]

Emodin reverses resistance to gemcitabine in pancreatic cancer.Dec 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2023 Jan ;25(1):7. Epub 2022 Nov 16. PMID: 36545274

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : Emodin

Diseases : Cancers: Drug Resistant, Pancreatic Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

Emodin sensitizes human pancreatic cancer cells to EGFR inhibitor through suppressing Stat3 signaling pathway.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Pancreas. 2008 May;36(4):353-62. PMID: 18437081

Article Published Date : May 01, 2008

Study Type : Animal Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Pancreatic Cancer

Additional Keywords : Omega 3/6 Ratio, Omega 6 Fatty Acids are Detrimental

[+]

Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Int J Cancer. 2009 Nov 11. PMID: 19908231

Article Published Date : Nov 11, 2009

Study Type : Transgenic Animal Study

Additional Links

Substances : Resveratrol

Diseases : Pancreatic Cancer

Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine, Drug-Plant-Vitamin Synergies

[+]

Sea cucumber contains a compound Frondoside A which has potent growth inhibitory effects against human pancreatic cancer cells.Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : Ann N Y Acad Sci. 2008 Sep;1138:181-98. PMID: 18837899

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Sea Cucumber

Diseases : Pancreatic Cancer

[+]

Seaweed polyphenols may inhibit pancreatic cancer relapse/recurrence by targeting therapy-orchestrated stem-cell signaling in residual cells.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Sulforaphane may do more than prevent cancer, but actively treat established pancreatic cancer.Oct 01, 2004

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Pubmed Data : Mol Cancer Ther. 2004 Oct;3(10):1239-48. PMID: 15486191

Article Published Date : Oct 01, 2004

Study Type : Animal Study

Additional Links

Substances : Broccoli

Diseases : Pancreatic Cancer

[+]

Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.Aug 01, 2010

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Pubmed Data : Mol Cancer Ther. 2010 Aug;9(8):2255-64. Epub 2010 Jul 20. PMID: 20647339

Article Published Date : Aug 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Pancreatic Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, NF-kappaB Inhibitor

Additional Keywords : Drug Synergy

[+]

The present results demonstrate that oridonin overcomes PANC-1/Gem cells gemcitabine reistance.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Onco Targets Ther. 2019 ;12:5751-5765. Epub 2019 Jul 17. PMID: 31410021

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Pubmed Data : Front Pharmacol. 2022 ;13:1068855. Epub 2022 Dec 23. PMID: 36618921

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Wogonin

Diseases : Pancreatic Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

[+]

A combination of lysine, proline, arginine, ascorbic acid and green tea extract inhibits a pancreatic cancer cell line. Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Int J Gastrointest Cancer. 2005;35(2):97-102. PMID: 15879623

Article Published Date : Jan 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Arginine, Green Tea, Lysine, Proline, Vitamin C

Diseases : Pancreatic Cancer

[+]

A combination of phenethyl isothiocyanate and TH588 has potential as a novel therapeutic strategy against pancreatic cancer.Feb 28, 2018

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Pubmed Data : Oncol Lett. 2018 Mar ;15(3):3240-3244. Epub 2017 Dec 29. PMID: 29435064

[+]

Acetyl-11-keto-β-boswellic acid suppresses invasion of pancreatic cancer cells.Jun 30, 2011

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Pubmed Data : Int J Cancer. 2011 Jul 1 ;129(1):23-33. Epub 2011 Mar 29. PMID: 21448932

Article Published Date : Jun 30, 2011

Study Type : In Vitro Study

Additional Links

Substances : acetyl-11-keto-beta-boswellic acid

Diseases : Pancreatic Cancer

Pharmacological Actions : Anti-metastatic

[+]

Active ingredients of Inula helenium L. exhibits similar anti-cancer effects as isoalantolactone in pancreatic cancer cells.Aug 31, 2020

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Pubmed Data : Nat Prod Res. 2020 Sep ;34(17):2539-2544. Epub 2019 Jan 19. PMID: 30661396

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Pubmed Data : Cancers (Basel). 2022 Jul 25 ;14(15). Epub 2022 Jul 25. PMID: 35892872

Article Published Date : Jul 24, 2022

Study Type : In Vitro Study

Additional Links

Substances : Apigenin

Diseases : Pancreatic Cancer

Pharmacological Actions : MicroRNA modulator

Additional Keywords : Tumor Microenvironment

[+]

Armed and targeted measles virus for chemovirotherapy of pancreatic cancer.Jul 31, 2011

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Pubmed Data : Mar Drugs. 2015 Jul ;13(7):4470-91. Epub 2015 Jul 20. PMID: 26204945

Article Published Date : Jun 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Seaweed: Brown

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Bee propolis is cytotoxic against a human pancreatic cancer cell line. Jul 02, 2009

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Pubmed Data : J Nat Prod.2009 Jul 2. PMID: 19572611

Article Published Date : Jul 02, 2009

Study Type : In Vitro Study

Additional Links

Substances : Bee Propolis

Diseases : Pancreatic Cancer

[+]

Berbamine enhances the efficacy of gefitinib by suppressing STAT3 signalling in pancreatic cancer cells.Dec 31, 2018

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Pubmed Data : Bioorg Med Chem. 2008 Jan 1;16(1):181-9. Epub 2007 Oct 5. PMID: 17950610

Article Published Date : Jan 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Bee Propolis

Diseases : Pancreatic Cancer

[+]

Cannabidiol and oxygen-ozone combination induce cytotoxicity in human pancreatic ductal adenocarcinoma cell lines.Sep 26, 2020

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Pubmed Data : Oncol Rep. 2017 Mar 21. Epub 2017 Mar 21. PMID: 28339071

Article Published Date : Mar 20, 2017

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative

[+]

Cardamonin promotes the apoptosis and chemotherapy sensitivity to gemcitabine of pancreatic cancer.Sep 30, 2021

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Pubmed Data : Dose Response. 2021 Oct-Dec;19(4):15593258211042163. Epub 2021 Dec 21. PMID: 34987330

Article Published Date : Sep 30, 2021

Study Type : In Vitro Study

Additional Links

Substances : Cardamonin

Diseases : Pancreatic Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

Carotenoids from red palm and green tea polyphenols exhibit chemopreventive effects on pancreatic cancer cell lines. Jan 01, 1998

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Pubmed Data : Pancreas. 1998 Jan;16(1):13-8. PMID: 9436857

Article Published Date : Jan 01, 1998

Study Type : In Vitro Study

Additional Links

Substances : Palm Oil

Diseases : Pancreatic Cancer

[+]

Carrot and carotene and multiple health outcomes: an umbrella review of the evidence.Mar 29, 2023

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Pubmed Data : J Sci Food Agric. 2023 Mar 30 ;103(5):2251-2261. Epub 2023 Jan 17. PMID: 36600678

Article Published Date : Mar 29, 2023

Study Type : Review

Additional Links

Substances : beta-Carotene, Carotenoids, Carrot

Diseases : Alzheimer's Disease, Breast Cancer, Cataract, Gastric Cancer, Head and Neck Cancer, Pancreatic Cancer, Prostate Cancer

Pharmacological Actions : Chemopreventive, Neuroprotective Agents

Additional Keywords : Risk Reduction

[+]

Catechin and inositol hexaphosphate (IP6) inhibit pancreatic cancer growth in vitro. Jul 01, 2007

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Pubmed Data : J Surg Res. 2007 Jul;141(1):115-9. PMID: 17574044

Article Published Date : Jul 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Catechin , Inositol Hexaphosphate

Diseases : Pancreatic Cancer

[+]

Chemovirotherapy of pancreatic adenocarcinoma by combining oncolytic vaccinia virus GLV-1h68 with nab-paclitaxel plus gemcitabine.Sep 14, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Ther Oncolytics. 2017 Sep 15 ;6:10-21. Epub 2017 Apr 19. PMID: 28607950

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Pathol. 2014 Sep 17. Epub 2014 Sep 17. PMID: 25232128

Article Published Date : Sep 16, 2014

Study Type : In Vitro Study

Additional Links

Substances : Anthocyanins, Chokeberry

Diseases : Pancreatic Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine, Natural Substance/Drug Synergy

[+]

Coix seed extract could augment the efficacy of gemcitabine therapy in pancreatic cancer cells.Oct 22, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2019 Oct 23 ;20(21). Epub 2019 Oct 23. PMID: 31652737

Article Published Date : May 05, 2009

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Pancreatic Cancer

Pharmacological Actions : Apoptotic

[+]

Curcumin could be candidate drug for targeting pancreatic cancer stem cells.Dec 27, 2015

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Pubmed Data : Cell Cycle. 2015 Dec 28:0. Epub 2015 Dec 28. PMID: 26709750

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2020 Jan ;121:109522. Epub 2019 Oct 29. PMID: 31675539

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Dates

Diseases : Pancreatic Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Plant Extracts

[+]

Deciphering the action mechanism of paeoniflorin in suppressing pancreatic cancer.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2022 ;13:1032282. Epub 2022 Oct 20. PMID: 36339551

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Paeoniflorin

Diseases : Pancreatic Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic

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A high intake of dietary fiber was associated with a reduced risk of pancreatic cancer.Dec 31, 2016

A high level of vitamin E might be a protective factor for populations at risk for pancreatic cancer.Dec 31, 2014

A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.Dec 31, 2018

Cruciferous vegetable intake might be inversely associated with the incidence of pancreatic cancer. Dec 31, 2014

Exposure to proton pump inhibitors and risk of pancreatic cancer.Jan 10, 2020

Higher dietary intakes of selenium, vitamin C, vitamin E, β-carotene and β-cryptoxanthin were associated with reduced pancreatic cancer risk.Jun 29, 2016

Meta-analysis: The use of insulin and insulin analogs increase the risk of various cancers.Oct 31, 2013

Nut consumption was significantly associated with a reduced risk of cancer incidence.Jun 30, 2015

Review: there is a consistently strong inverse correlations with solar UVB for 15 types of cancers.Jan 01, 2012

The present meta-analysis supports that fruit and vegetable intake is associated inversely with the risk of pancreatic cancer.Jun 10, 2015

The results from this meta-analysis suggested that the higher intake of vitamin C might reduce the risk of pancreatic cancer.Dec 31, 2014

This meta-analysis found that vitamin intake can decrease the risk of pancreatic cancer.Feb 28, 2018

A longer overall survival in patients with pancreatic cancer was found in those who had sufficient pre-diagnostic plasma levels of 25(OH)D.Jun 19, 2016

A superfine and dispersed form of beta-glucan (lentinan) is safe and effective for advanced patients' survival and improvement of quality of life. Feb 01, 1990

Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.Mar 01, 2006

Aloe significantly improves chemotherapy treatment coutcomes in patients with metastatic gastric, pancreatic and colorectal cancers. Jan 01, 2009

Alpha lipoic acid may provide an effective adjuvant in the treatment of metastatic and nonmetastatic pancreatic cancer.Dec 01, 2009

Alpha lipoic may have a profound therapeutic role in the treatment of pancreatic cancer. Mar 01, 2006

C-reactive protein is an indicator of the aggressiveness of advanced pancreatic cancer.Dec 31, 2015

Carrot intake and risk of developing cancer: A prospective cohort study. Jan 28, 2023

Chemotherapy for pancreatic cancer results in median survival and 1-year survival times of 4.9 months (95% CI, 4.5 to 5.6) and 16% for GEM, 6.2 months (95% CI, 5.4 to 6.9), and 21% for GEM FDR, and 5.7 months (95% CI, 4.9 to 6.5) and 21% for GEMOX.Aug 10, 2009

Chemotherapy with gemcitabine results in median progression-free survival (PFS) and overall survival (OS) times for the entire population were 4.4 months (95% confidence interval [CI], 3.5-5.1 months) and 7.7 months (95% CI, 6.3-8.8 months), respectively,Jan 01, 2010

Cigarette smoking is an independent risk factor for pancreatic cancer.Mar 01, 1992

Coffee consumption is associated with a reduced risk for pancreatic cancer. Mar 05, 2008

Combination chemotherapy and chemoradiation does not improve overall survival in inoperabe advanced pancreatic cancer over single chemotherapy alone.Jan 01, 2009

Cost-effectiveness of real-world administration of concomitant Viscum album L. therapy for the treatment of stage IV pancreatic cancer.Dec 31, 2019

Curcumin has significant therapeutic activity in patients with pancreatic cancer.Jul 15, 2008

Curcumin may enhance the therapeutic effect of gemcitabine in the treatment of advanced pancreatic cancer. Nov 24, 2009

Deuterium depletion inhibits cell proliferation, RNA and nuclear membrane turnover to enhance survival in pancreatic cancer.Dec 31, 2020

Dietary CML-AGE consumption was associated with modestly increased risk of pancreatic cancer in men and may partially explain the positive association between red meat and pancreatic cancer.Dec 31, 2014

Dietary intake of lycopene is associated with reduced pancreatic cancer risk.Mar 01, 2005

Dl-alpha-tocopherol acetate supplementation is associated with increased mortality in pancreatic cancer patients. Jul 01, 1999

Efficacy of Lentinula edodes mycelia extract on chemotherapy-related tasted disorders in pancreatic cancer patients.Dec 31, 2022

Elevated neutrophil to lymphocyte ratio is linked poorer survival in advanced pancreatic cancer. Jul 05, 2010

EPA (eicosapentaenoic acid) induces programmed cell death in human pancreatic cancer cells. Oct 01, 2005

Extended sitting time at work was associated with an increased risk of pancreas cancer in men and lung cancer in women.Jan 10, 2020

Fish oil improves weight loss in pancreatic cancer patients. Jan 01, 2001

Frequent nut consumption is inversely associated with risk of pancreatic cancer.Nov 25, 2013

High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.Jan 06, 2017

High fructose and sucrose intakes may play a role in pancreatic cancer etiology. Conditions such as overweight or obesity in which a degree of insulin resistance may be present may also be important.Nov 01, 2007

Higher methionine intake may reduce the risk of pancreatic cancer. Jan 01, 2007

Increasing vegetable and fruit consumption protects against developing pancreatic cancer. Sep 01, 2005

L-Carnitine supplementation reduces malnutrition, increases bodyweight, improves body composition and overall survival time.Dec 31, 2011

Low levels of serum cholesterol has been connected to increased types of mortality.Jul 01, 1992

Magnesium intake may be beneficial in terms of primary prevention of pancreatic cancer.Nov 30, 2015

Mean fasting serum fructose level was significantly higher at 5.7+/-2.5 mM in patients with pancreatic cancer than those with no pancreatic cancer. Aug 01, 2009

Mistletoe extract is superior to gemcitabine in patients with inoperable locally advanced pancreatic cancer. May 01, 2005

Mistletoe may act synergistically with chemotherapy against pancreatic cancer. Jun 01, 2010

Nut consumption reduces the risk of pancreatic cancer in women.Oct 21, 2013

nuts and peanut butter might reduce pancreatic cancer risk in men.Jan 21, 2018

Of the 15 patients, 1 showed confirmed partial response and 4 patients had stable disease.Sep 28, 2016

Omega-3 fatty acid supplementation in patients with unresectable pancreatic and bile duct cancer may improve cancer cachexia.Dec 31, 2017

Oral curcumin is safe and feasible in patients with pancreatic cancer.Sep 22, 2010