Pancreatic Cancer

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269 Substances Researched for Pancreatic Cancer
NameACCKFocus
Vitamin C1397Locked
Vitamin E1076Locked
Curcumin3672Locked
Vitamin D865Locked
Nuts652Locked
Mistletoe534Locked
Fruit: All331Locked
Vegetables: All 331Locked
Vitamin B-12230Locked
Sulforaphane1728Locked
Ginsenosides526Locked
Cruciferous Vegetables225Locked
Flavonoids1124Locked
Alpha-Lipoic Acid322Locked
Selenium222Locked
beta-Carotene221Locked
Cryptoxanthin120Locked
Fiber120Locked
Omega-3 Fatty Acids719Locked
Quercetin1517Locked
Apigenin1016Locked
Oridonin916Locked
Resveratrol1416Locked
EGCG (Epigallocatechin gallate)1215Locked
Tocotrienol: Delta515Locked
Thymoquinone1014Locked
Carotenoids413Locked
Emodin813Locked
Genistein1113Locked
Aloe Vera211Locked
Anthocyanins211Locked
Carrot211Locked
Lycopene211Locked
Tomato211Locked
Beta-glucan110Locked
Burdock110Locked
Cholesterol 110Locked
Coffee110Locked
EPA (Eicosapentaenoic Acid)110Locked
Fish Oil110Locked
Folate: Dietary110Locked
Folic Acid 110Locked
Garlic110Locked
L-Carnitine110Locked
Lentinan110Locked
Magnesium110Locked
Methionine110Locked
Shiitake Mushroom 110Locked
Stearic Acid (stearate) 110Locked
Water: Deuterium Depleted110Locked
Ginger38Locked
Polyphenols68Locked
Cannabinoids 67Locked
Chrysin37Locked
Elecampane77Locked
Naringenin 27Locked
Xanthohumol67Locked
Berbamine46Locked
Fisetin66Locked
Pterostilbene56Locked
Spirulina26Locked
Cannabidiol35Locked
Cucurbitacin B 35Locked
Dandelion 15Locked
Ellagic Acid55Locked
Green Tea45Locked
Horse Chestnut35Locked
Indole-3-Carbinol45Locked
Melatonin45Locked
Shikonin35Locked
Zerumbone15Locked
Zyflamend35Locked
6-Shogaol24Locked
Artemisinin34Locked
Baicalein34Locked
Bee Propolis44Locked
Berberine44Locked
Broccoli24Locked
Capsaicin24Locked
Ginkgo biloba34Locked
NAC (N-acetyl-L-cysteine)34Locked
Neem44Locked
Noni24Locked
Paeoniflorin44Locked
Pancreatic Enzymes34Locked
Piperlongumine 34Locked
Viruses: Beneficial44Locked
Vitamin C: Intravenous 24Locked
Wogonin34Locked
Ashwagandha23Locked
Benzyl isothiocyanate 23Locked
Betulinic acid33Locked
Bitter Melon23Locked
Bromelain23Locked
Celastrol13Locked
Crocin23Locked
Deguelin33Locked
Frankincense23Locked
Fucoxanthin 23Locked
Gingerol 23Locked
Grape Seed Extract23Locked
Lactobacillus casei13Locked
Lactobacillus reuteri13Locked
Nexrutine (Phellodendrom)33Locked
Phenethyl isothiocyanate33Locked
Piceatannol 23Locked
Seaweed: Brown 23Locked
Silibinin23Locked
Tocotrienol: Gamma33Locked
Ursolic Acid13Locked
Wheat Germ33Locked
Adlay22Locked
Andrographolide22Locked
Astaxanthin12Locked
Basil12Locked
Bee Venom22Locked
Berries: All22Locked
Bitter Apple12Locked
Black Tea12Locked
Boswellia12Locked
Calcium12Locked
Cannabis22Locked
Catechin 22Locked
Cayenne12Locked
Citrus Peel 12Locked
Cordyceps Militaris12Locked
Cucurbitacin D22Locked
Curcumin: Lipidated12Locked
Curcumol12Locked
Dates22Locked
Deuterium (heavy water) 22Locked
Echinacea22Locked
Fenugreek12Locked
Fermented Foods and Beverages12Locked
Gallic Acid22Locked
Gold (nanoparticles)22Locked
Graviola 22Locked
Hesperidin12Locked
Honokiol22Locked
Inositol Hexaphosphate22Locked
Isoflavones22Locked
Isothiocyanates22Locked
Kaempferol22Locked
Lactoferrin12Locked
Lichens22Locked
Lime: Key22Locked
Long Pepper12Locked
Luteolin22Locked
Magnolol12Locked
Mangosteen12Locked
Mimosa pudica12Locked
Mulberry22Locked
Nigella sativa (aka Black Seed)22Locked
Orthosiphon12Locked
Palm Oil22Locked
Peony12Locked
Phlorotannins22Locked
Pomegranate22Locked
Poria cocos22Locked
Psychedelics:All 12Locked
Saffron22Locked
Salvia miltiorrhiza22Locked
Sea Cucumber12Locked
Seaweed12Locked
Silver (nanoparticles)12Locked
Sophora Flavescens12Locked
Sprouts12Locked
Tanshinone IIA22Locked
Tomatidine 12Locked
Triphala12Locked
Walnut22Locked
Acai11Locked
Agaricus Blazei11Locked
Agrimony11Locked
Apricot11Locked
Arctigenin11Locked
Arginine11Locked
Arugula11Locked
Asparagus11Locked
Bael 11Locked
Banana11Locked
Banana Peel11Locked
Beet11Locked
Beta Sitosterol11Locked
Beta-Elemene11Locked
Betel11Locked
Biochanin A11Locked
Bisdemethoxycurcumin11Locked
Black Raspberry11Locked
Blackberries11Locked
Blueberry11Locked
Buckwheat11Locked
Caffeic acid phenethyl ester11Locked
Cannabinoids: Synthetic11Locked
Cardamonin11Locked
Carnitine11Locked
Chia11Locked
Chinese Skullcap 11Locked
Chlorogenic Acid11Locked
Chokeberry11Locked
Coptidis rhizoma11Locked
Corn Silk11Locked
Cranberry11Locked
Cucumber11Locked
DHA (Docosahexaenoic Acid)11Locked
DIM (3,3'-diindolylmethane)11Locked
Daidzein11Locked
Damnacanthal11Locked
Diosgenin11Locked
Dracaena draco11Locked
Eggplant11Locked
Elderberry11Locked
Evening Primrose Oil11Locked
Ferulic acid11Locked
Feverfew11Locked
Fig11Locked
Fucoidan11Locked
Garcinia indica11Locked
Geraniol 11Locked
Ginseng, unspecified species11Locked
Glutamine11Locked
Goji11Locked
Grapes11Locked
Haplophyllum perforatum11Locked
Harmine11Locked
Helenalin11Locked
Horsetail11Locked
Hydroxytyrosol11Locked
Icogenin 11Locked
Indian Gooseberry11Locked
Kimchi11Locked
Kiwifruit11Locked
Lysine11Locked
Moringa oleifera11Locked
Myricetin11Locked
Nobiletin 11Locked
Nordihydroguaiaretic acid (NDGA)11Locked
Oat Bran11Locked
Oleocanthal11Locked
Oleuropein11Locked
Olive leaf extract11Locked
Oxygen Therapies11Locked
Paeonol11Locked
Panaxadiol11Locked
Parthenolide11Locked
Phellinus Linteus11Locked
Phloretin11Locked
Proline11Locked
Puerarin11Locked
Pycnogenol (Pine Bark)11Locked
Raspberry11Locked
Reishi Mushroom11Locked
Rhubarb11Locked
Rice Bran11Locked
Saikosaponin11Locked
Sesame Seeds11Locked
Spinach11Locked
Stevia11Locked
Tocotrienol: Alpha11Locked
Triptolide11Locked
Ume (Japanese apricot) 11Locked
Vitamin E: delta-tocopherol11Locked
Vitamin K11Locked
Wasabi11Locked
Watermelon11Locked
Wormwood11Locked
acetyl-11-keto-beta-boswellic acid11Locked
cottonseed oil (gossypol)11Locked
St. Johns Wort10Locked
18 Problem Substances Researched for Pancreatic Cancer
NameACCKFocus
Insulin 120Locked
Meat220Locked
Proton-Pump Inhibitors120Locked
Fructose211Locked
Dl-alpha-tocopherol acetate110Locked
Foods: High Glycemic Load110Locked
Meat: Cooked110Locked
Statin Drugs110Locked
Sugar Sweetened Beverages110Locked
Sugary soda110Locked
Tobacco: Smoking110Locked
Bisphenol A 11Locked
High Fructose Corn Syrup11Locked
Hydrocarbons11Locked
Mineral Oil11Locked
N-Nitrosamines11Locked
Paraffin11Locked
Polycyclic aromatic hydrocarbon11Locked
12 Therapeutic Actions Researched for Pancreatic Cancer
NameACCKFocus
Sunlight exposure120Locked
Acupressure110Locked
Dietary Modification: Low Glycemic Diet110Locked
Integrative Medicine110Locked
Ultrasound therapy110Locked
Dietary Modification: Low Carbohydrate/Ketogenic34Locked
Dietary Modification: Macrobiotic Diet11Locked
Electric Stimulation 11Locked
Infrared Light11Locked
Ozone Therapy 11Locked
Photobiomodulation11Locked
Qigong11Locked
4 Problematic Actions Researched for Pancreatic Cancer
NameACCKFocus
Chemotherapy330Locked
Overnutrition12Locked
Western Diet12Locked
Fine Needle Aspiration11Locked
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View the Evidence:
564 Abstracts with Pancreatic Cancer Research

[+]

Ultra-processed food consumption and cancer risk.May 31, 2023

Pubmed Data : Clin Nutr. 2023 Jun ;42(6):919-928. Epub 2023 Mar 30. PMID: 37087831
Article Published Date : May 31, 2023
Study Type : Meta Analysis, Review
Additional Links
Diseases : Colorectal Cancer, Leukemia: Chronic Lymphocytic Leukemia (CLL), Pancreatic Cancer
Additional Keywords : Ultra-Processed Food
[+]

A high intake of dietary fiber was associated with a reduced risk of pancreatic cancer.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asia Pac J Clin Nutr. 2017 Jan ;26(1):89-96. PMID: 28049267
Article Published Date : Dec 31, 2016
Study Type : Meta Analysis
Additional Links
Substances : Fiber
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

A high level of vitamin E might be a protective factor for populations at risk for pancreatic cancer.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2015 ;21:1249-55. Epub 2015 May 1. PMID: 25929754
Article Published Date : Dec 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Vitamin E
Diseases : Pancreatic Cancer
Additional Keywords : Risk Reduction
[+]

A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:2417418. Epub 2019 Dec 17. PMID: 31929811
Article Published Date : Dec 31, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Ginsenosides
Diseases : Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Liver Cancer, Pancreatic Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antiproliferative , Chemotherapeutic
[+]

Cruciferous vegetable intake might be inversely associated with the incidence of pancreatic cancer. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Surg Oncol. 2015 ;13:44. Epub 2015 Feb 12. PMID: 25889229
Article Published Date : Dec 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Cruciferous Vegetables
Diseases : Pancreatic Cancer
Additional Keywords : Risk Reduction
[+]

Exposure to proton pump inhibitors and risk of pancreatic cancer.Jan 10, 2020

Pubmed Data : Expert Opin Drug Saf. 2020 Jan 11. Epub 2020 Jan 11. PMID: 31928106
Article Published Date : Jan 10, 2020
Study Type : Meta Analysis
Additional Links
Diseases : Pancreatic Cancer
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Higher dietary intakes of selenium, vitamin C, vitamin E, β-carotene and β-cryptoxanthin were associated with reduced pancreatic cancer risk.Jun 29, 2016

Pubmed Data : Int J Food Sci Nutr. 2016 Jun 30:1-13. Epub 2016 Jun 30. PMID: 27356952
Article Published Date : Jun 29, 2016
Study Type : Meta Analysis
Additional Links
Substances : beta-Carotene, Cryptoxanthin, Selenium, Vitamin C, Vitamin E
Diseases : Pancreatic Cancer
Pharmacological Actions : Antioxidants
Additional Keywords : Risk Reduction
[+]

Meta-analysis: The use of insulin and insulin analogs increase the risk of various cancers.Oct 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Drug Saf. 2013 Nov ;8(5):333-48. PMID: 24215311
Article Published Date : Oct 31, 2013
Study Type : Meta Analysis
Additional Links
Diseases : Kidney Cancer, Liver Cancer, Lung Cancer, Pancreatic Cancer, Respiratory Cancers, Stomach Cancer
Problem Substances : Insulin
Adverse Pharmacological Actions : Carcinogenic
[+]

Nut consumption was significantly associated with a reduced risk of cancer incidence.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Rev. 2015 Jul ;73(7):409-25. PMID: 26081452
Article Published Date : Jun 30, 2015
Study Type : Meta Analysis, Review
Additional Links
Substances : Nuts
Diseases : Colon Cancer, Pancreatic Cancer
Additional Keywords : Risk Reduction
[+]

Review: there is a consistently strong inverse correlations with solar UVB for 15 types of cancers.Jan 01, 2012

Pubmed Data : Anticancer Res. 2012 Jan ;32(1):223-36. PMID: 22213311
Article Published Date : Jan 01, 2012
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Bladder Cancer, Breast Cancer, Cervical Cancer, Colon Cancer, Colorectal Cancer, Endometrial Cancer, Esophageal Cancer, Hodgkin Lymphoma, Lung Cancer, Non-Hodgkin Lymphoma, Ovarian Cancer, Pancreatic Cancer, Renal Cancer, Vulvar Cancer
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Chemopreventive
[+]

The present meta-analysis supports that fruit and vegetable intake is associated inversely with the risk of pancreatic cancer.Jun 10, 2015

Pubmed Data : Eur J Cancer Prev. 2015 Jun 11. Epub 2015 Jun 11. PMID: 26075658
Article Published Date : Jun 10, 2015
Study Type : Meta Analysis
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Pancreatic Cancer
Additional Keywords : Risk Reduction
[+]

The results from this meta-analysis suggested that the higher intake of vitamin C might reduce the risk of pancreatic cancer.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:13973. Epub 2015 Sep 11. PMID: 26360104
Article Published Date : Dec 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Vitamin C
Diseases : Pancreatic Cancer
Additional Keywords : Risk Reduction
[+]

This meta-analysis found that vitamin intake can decrease the risk of pancreatic cancer.Feb 28, 2018

Pubmed Data : Medicine (Baltimore). 2018 Mar ;97(13):e0114. PMID: 29595633
Article Published Date : Feb 28, 2018
Study Type : Meta Analysis
Additional Links
Substances : Vitamin B-12, Vitamin D
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

A longer overall survival in patients with pancreatic cancer was found in those who had sufficient pre-diagnostic plasma levels of 25(OH)D.Jun 19, 2016

Pubmed Data : J Clin Oncol. 2016 Jun 20. Epub 2016 Jun 20. PMID: 27325858
Article Published Date : Jun 19, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Pancreatic Cancer, Vitamin D Deficiency
Additional Keywords : Risk Reduction
[+]

A superfine and dispersed form of beta-glucan (lentinan) is safe and effective for advanced patients' survival and improvement of quality of life. Feb 01, 1990

Pubmed Data : Hepatogastroenterology. 1990 Feb;37(1):72-80. PMID: 19453066
Article Published Date : Feb 01, 1990
Study Type : Human Study
Additional Links
Substances : Beta-glucan, Lentinan
Diseases : Pancreatic Cancer
[+]

Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.Mar 01, 2006

Pubmed Data : J Nutr. 2006 Mar;136(3 Suppl):816S-820S. PMID: 16484572
Article Published Date : Mar 01, 2006
Study Type : Human Study
Additional Links
Substances : Garlic
Diseases : Colon Cancer, Liver Cancer, Low Immune Function: Natural Killer Cells, Pancreatic Cancer
Additional Keywords : Drug Side Effect Attenuation, Plant Extracts
[+]

Aloe significantly improves chemotherapy treatment coutcomes in patients with metastatic gastric, pancreatic and colorectal cancers. Jan 01, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : In Vivo. 2009 Jan-Feb;23(1):171-5. PMID: 19368145
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Substances : Aloe Vera
Diseases : Cancer Metastasis, Cancers: All, Colorectal Cancer, Gastric Cancer, Pancreatic Cancer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Alpha lipoic acid may provide an effective adjuvant in the treatment of metastatic and nonmetastatic pancreatic cancer.Dec 01, 2009

Pubmed Data : Integr Cancer Ther. 2009 Dec;8(4):416-22. PMID: 20042414
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Liver Cancer, Pancreatic Cancer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Alpha lipoic may have a profound therapeutic role in the treatment of pancreatic cancer. Mar 01, 2006

Pubmed Data : Integr Cancer Ther. 2006 Mar;5(1):83-9. PMID: 16484716
Article Published Date : Mar 01, 2006
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Pancreatic Cancer
[+]

C-reactive protein is an indicator of the aggressiveness of advanced pancreatic cancer.Dec 31, 2015

Pubmed Data : Pancreas. 2016 Jan ;45(1):110-6. PMID: 26566216
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Pancreatic Cancer
Additional Keywords : Increased Risk
[+]

Carrot intake and risk of developing cancer: A prospective cohort study. Jan 28, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Jan 29 ;15(3). Epub 2023 Jan 29. PMID: 36771385
Article Published Date : Jan 28, 2023
Study Type : Human Study
Additional Links
Substances : Carrot
Diseases : Colorectal Cancer, Leukemia, Pancreatic Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Risk Reduction
[+]

Chemotherapy for pancreatic cancer results in median survival and 1-year survival times of 4.9 months (95% CI, 4.5 to 5.6) and 16% for GEM, 6.2 months (95% CI, 5.4 to 6.9), and 21% for GEM FDR, and 5.7 months (95% CI, 4.9 to 6.5) and 21% for GEMOX.Aug 10, 2009

Pubmed Data : J Clin Oncol. 2009 Aug 10;27(23):3778-85. Epub 2009 Jul 6. PMID: 19581537
Article Published Date : Aug 10, 2009
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
Anti Therapeutic Actions : Chemotherapy
[+]

Chemotherapy with gemcitabine results in median progression-free survival (PFS) and overall survival (OS) times for the entire population were 4.4 months (95% confidence interval [CI], 3.5-5.1 months) and 7.7 months (95% CI, 6.3-8.8 months), respectively,Jan 01, 2010

Pubmed Data : Oncologist. 2010;15(2):e1-4. PMID: 20189980
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
Anti Therapeutic Actions : Chemotherapy
[+]

Cigarette smoking is an independent risk factor for pancreatic cancer.Mar 01, 1992

Pubmed Data : Epidemiology. 1992 Mar;3(2):164-70. PMID: 1576222
Article Published Date : Mar 01, 1992
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
Problem Substances : Tobacco: Smoking
Adverse Pharmacological Actions : Carcinogenic
[+]

Coffee consumption is associated with a reduced risk for pancreatic cancer. Mar 05, 2008

Pubmed Data : J Ethnopharmacol. 2008 Mar 5;116(2):325-32. Epub 2007 Dec 4. PMID: 18090127
Article Published Date : Mar 05, 2008
Study Type : Human Study
Additional Links
Substances : Coffee
Diseases : Pancreatic Cancer
Additional Keywords : Risk Reduction
[+]

Combination chemotherapy and chemoradiation does not improve overall survival in inoperabe advanced pancreatic cancer over single chemotherapy alone.Jan 01, 2009

Pubmed Data : Cochrane Database Syst Rev. 2009(4):CD002093. Epub 2009 Oct 7. PMID: 19821291
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents
Additional Keywords : Drug: 5-flourouracil, Drug: Gemcitabine
Anti Therapeutic Actions : Chemotherapy
[+]

Cost-effectiveness of real-world administration of concomitant Viscum album L. therapy for the treatment of stage IV pancreatic cancer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:3543568. Epub 2020 Mar 12. PMID: 32256640
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Mistletoe
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Curcumin has significant therapeutic activity in patients with pancreatic cancer.Jul 15, 2008

Pubmed Data : Clin Cancer Res. 2008 Jul 15;14(14):4491-9. PMID: 18628464
Article Published Date : Jul 15, 2008
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
[+]

Curcumin may enhance the therapeutic effect of gemcitabine in the treatment of advanced pancreatic cancer. Nov 24, 2009

Pubmed Data : Curr Med Chem. 2009 Nov 24. PMID: 20214562
Article Published Date : Nov 24, 2009
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Deuterium depletion inhibits cell proliferation, RNA and nuclear membrane turnover to enhance survival in pancreatic cancer.Dec 31, 2020

Pubmed Data : Cancer Control. 2021 Jan-Dec;28:1073274821999655. PMID: 33760674
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Water: Deuterium Depleted
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Dietary CML-AGE consumption was associated with modestly increased risk of pancreatic cancer in men and may partially explain the positive association between red meat and pancreatic cancer.Dec 31, 2014

Pubmed Data : Am J Clin Nutr. 2015 Jan ;101(1):126-34. Epub 2014 Nov 19. PMID: 25527756
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Advanced Glycation End products (AGE), Pancreatic Cancer
Additional Keywords : Increased Risk
Problem Substances : Meat
[+]

Dietary intake of lycopene is associated with reduced pancreatic cancer risk.Mar 01, 2005

Pubmed Data : J Nutr. 2005 Mar;135(3):592-7. PMID: 15735099
Article Published Date : Mar 01, 2005
Study Type : Human Study
Additional Links
Substances : Lycopene, Tomato
Diseases : Pancreatic Cancer
[+]

Dl-alpha-tocopherol acetate supplementation is associated with increased mortality in pancreatic cancer patients. Jul 01, 1999

Pubmed Data : Cancer. 1999 Jul 1;86(1):37-42. PMID: 10391561
Article Published Date : Jul 01, 1999
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer, Smoking
Problem Substances : Dl-alpha-tocopherol acetate
[+]

Efficacy of Lentinula edodes mycelia extract on chemotherapy-related tasted disorders in pancreatic cancer patients.Dec 31, 2022

Pubmed Data : Nutr Cancer. 2023 ;75(1):236-246. Epub 2022 Aug 11. PMID: 35950537
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Substances : Shiitake Mushroom
Diseases : Chemotherapy, Pancreatic Cancer, Taste Disorders
Pharmacological Actions : Chemoprotective Agents
Additional Keywords : Plant Extracts
[+]

Elevated neutrophil to lymphocyte ratio is linked poorer survival in advanced pancreatic cancer. Jul 05, 2010

Pubmed Data : Biomarkers. 2010 Jul 5. Epub 2010 Jul 5. PMID: 20602543
Article Published Date : Jul 05, 2010
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
[+]

EPA (eicosapentaenoic acid) induces programmed cell death in human pancreatic cancer cells. Oct 01, 2005

Pubmed Data : Nutrition. 2005 Oct;21(10):1010-7. PMID: 16157238
Article Published Date : Oct 01, 2005
Study Type : Human Study
Additional Links
Substances : EPA (Eicosapentaenoic Acid)
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
[+]

Extended sitting time at work was associated with an increased risk of pancreas cancer in men and lung cancer in women.Jan 10, 2020

Pubmed Data : Cancer Sci. 2020 Jan 11. Epub 2020 Jan 11. PMID: 31925977
Article Published Date : Jan 10, 2020
Study Type : Human Study
Additional Links
Diseases : Lung Cancer, Pancreatic Cancer, Sitting Sickness
Additional Keywords : Risk Factors
[+]

Fish oil improves weight loss in pancreatic cancer patients. Jan 01, 2001

Pubmed Data : 1 : Nutr Cancer. 2001;40(2):118-24. PMID: 11962246
Article Published Date : Jan 01, 2001
Study Type : Human Study
Additional Links
Substances : Fish Oil
Diseases : Cachexia, Pancreatic Cancer
[+]

Frequent nut consumption is inversely associated with risk of pancreatic cancer.Nov 25, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Cancer. 2013 Nov 26 ;109(11):2911-6. Epub 2013 Oct 22. PMID: 24149179
Article Published Date : Nov 25, 2013
Study Type : Human Study
Additional Links
Substances : Nuts
Diseases : Pancreatic Cancer
Additional Keywords : Risk Reduction
[+]

High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis.Jan 06, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 12 7 ;7(1):17188. Epub 2017 Dec 7. PMID: 29215048
Article Published Date : Jan 06, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Cancer Metastasis, Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

High fructose and sucrose intakes may play a role in pancreatic cancer etiology. Conditions such as overweight or obesity in which a degree of insulin resistance may be present may also be important.Nov 01, 2007

Pubmed Data : Am J Clin Nutr. 2007 Nov;86(5):1495-501. PMID: 17991664
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Obesity, Overweight , Pancreatic Cancer
Additional Keywords : Diseases that are Linked
[+]

Higher methionine intake may reduce the risk of pancreatic cancer. Jan 01, 2007

Pubmed Data : Gastroenterology. 2007 Jan;132(1):113-8. Epub 2006 Oct 12. PMID: 17241865
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Methionine
Diseases : Pancreatic Cancer
[+]

Increased vitamin C intake is associated with decreased pancreatic cancer risk.Jul 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Oncol. 2024 Aug ;15(4):543-549. Epub 2024 Jul 5. PMID: 38993260
Article Published Date : Jul 31, 2024
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
[+]

Increasing vegetable and fruit consumption protects against developing pancreatic cancer. Sep 01, 2005

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2093-7. PMID: 16172215
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Pancreatic Cancer
[+]

L-Carnitine supplementation reduces malnutrition, increases bodyweight, improves body composition and overall survival time.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2012 ;11:52. Epub 2012 Jul 23. PMID: 22824168
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : L-Carnitine
Diseases : Cachexia, Muscle Atrophy , Pancreatic Cancer
Additional Keywords : Nutrional Supplements
[+]

Low levels of serum cholesterol has been connected to increased types of mortality.Jul 01, 1992

Pubmed Data : Arch Intern Med. 1992 Jul ;152(7):1490-500. PMID: 1627030
Article Published Date : Jul 01, 1992
Study Type : Human Study
Additional Links
Substances : Cholesterol
Diseases : Alcohol Addiction, Cerebral Hemorrhage, Hepatic Cirrhosis, Liver Cancer, Pancreatic Cancer, Stroke: Hemorrhagic , Suicidal Behavior
[+]

Magnesium intake may be beneficial in terms of primary prevention of pancreatic cancer.Nov 30, 2015

Pubmed Data : Br J Cancer. 2015 Dec 1 ;113(11):1615-21. Epub 2015 Nov 10. PMID: 26554653
Article Published Date : Nov 30, 2015
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Pancreatic Cancer
Additional Keywords : Risk Reduction
[+]

Mean fasting serum fructose level was significantly higher at 5.7+/-2.5 mM in patients with pancreatic cancer than those with no pancreatic cancer. Aug 01, 2009

Pubmed Data : Pancreas. 2009 Aug;38(6):706-12. PMID: 19506535
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Diseases : Fructose-Induced Toxicity , Pancreatic Cancer
Problem Substances : Fructose
[+]

Mistletoe extract is superior to gemcitabine in patients with inoperable locally advanced pancreatic cancer. May 01, 2005

Pubmed Data : Anticancer Res. 2005 May-Jun;25(3B):1969-75. PMID: 16158932
Article Published Date : May 01, 2005
Study Type : Human Study
Additional Links
Substances : Mistletoe
Diseases : Pancreatic Cancer
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Mistletoe may act synergistically with chemotherapy against pancreatic cancer. Jun 01, 2010

Pubmed Data : Curr Mol Med. 2010 Jun;10(4):430-9. PMID: 20455850
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Mistletoe
Diseases : Pancreatic Cancer
Additional Keywords : Drug: Gemcitabine, Drug-Plant-Vitamin Synergies
[+]

Nut consumption reduces the risk of pancreatic cancer in women.Oct 21, 2013

Article Published Date : Oct 21, 2013
Study Type : Human Study
Additional Links
Substances : Nuts
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
[+]

nuts and peanut butter might reduce pancreatic cancer risk in men.Jan 21, 2018

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2018 Jan 22. Epub 2018 Jan 22. PMID: 29358224
Article Published Date : Jan 21, 2018
Study Type : Human Study
Additional Links
Substances : Nuts
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
[+]

Of the 15 patients, 1 showed confirmed partial response and 4 patients had stable disease.Sep 28, 2016

Pubmed Data : Cancer Sci. 2016 Sep 29. Epub 2016 Sep 29. PMID: 27685612
Article Published Date : Sep 28, 2016
Study Type : Human Study
Additional Links
Substances : Burdock
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Additional Keywords : Plant Extracts
[+]

Omega-3 fatty acid supplementation in patients with unresectable pancreatic and bile duct cancer may improve cancer cachexia.Dec 31, 2017

Pubmed Data : Anticancer Res. 2018 04 ;38(4):2369-2375. PMID: 29599363
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Bile Duct Cancer, Cachexia: Cancer, Pancreatic Cancer
Pharmacological Actions : Anti-Cachexic Agents
[+]

Oral curcumin is safe and feasible in patients with pancreatic cancer.Sep 22, 2010

Pubmed Data : Cancer Chemother Pharmacol. 2010 Sep 22. Epub 2010 Sep 22. PMID: 20859741
Article Published Date : Sep 22, 2010
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Additional Keywords : Drug Synergy
[+]

Pancreatic cancer risk may be associated with higher pesticide and herbicide exposure.Oct 01, 1998

Pubmed Data : Int J Epidemiol. 1998 Oct;27(5):781-7. PMID: 9839733
Article Published Date : Oct 01, 1998
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
[+]

Pancreatic disease may be caused by hepatic detoxification caused by excessive consumption of drugs, cigarettes, alcohol and coffee.Oct 29, 1983

Pubmed Data : Lancet. 1983 Oct 29;2(8357):1000-3. PMID: 6138545
Article Published Date : Oct 29, 1983
Study Type : Human Study
Additional Links
Diseases : Alcohol Toxicity , Pancreatic Cancer, Pancreatic Diseases, Tobacco Toxicity
[+]

Pharmacological ascorbate reduces radiation-induced normal tissue toxicity and enhances tumor radiosensitization in pancreatic cancer.Sep 24, 2018

Pubmed Data : Cancer Res. 2018 Sep 25. Epub 2018 Sep 25. PMID: 30254147
Article Published Date : Sep 24, 2018
Study Type : Human Study, In Vitro Study
Additional Links
Substances : Vitamin C
Diseases : Pancreatic Cancer
Pharmacological Actions : Radioprotective, Radiosensitizer
[+]

Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells.Jan 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2023 Feb ;158:114076. Epub 2022 Dec 13. PMID: 36516693
Article Published Date : Jan 31, 2023
Study Type : Human Study
Additional Links
Substances : Anthocyanins
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, NF-kappaB Inhibitor
[+]

Poorly controlled diabetes may be associated with a higher possibility of pancreatic cancer.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2016 Jun ;95(24):e3921. PMID: 27311001
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Pancreatic Cancer
Additional Keywords : Risk Factors
[+]

Pretreatment C-reactive protein level predicts outcome and patterns of failure after chemoradiotherapy for locally advanced pancreatic cancer.Oct 31, 2015

Pubmed Data : Pancreatology. 2015 Nov-Dec;15(6):694-700. Epub 2015 Oct 14. PMID: 26601881
Article Published Date : Oct 31, 2015
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Pancreatic Cancer
Additional Keywords : Risk Factors
[+]

Red and processed meats may be involved in pancreatic carcinogenesis.Apr 03, 2017

Pubmed Data : Pancreas. 2017 Apr 4. Epub 2017 Apr 4. PMID: 28375948
Article Published Date : Apr 03, 2017
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
Additional Keywords : Risk Factors
Problem Substances : Meat: Cooked
[+]

Reducing dietary sugar, glycemic load and insulin levels may reduce the risk of pancreatic cancer. Sep 04, 2002

Pubmed Data : J Natl Cancer Inst. 2002 Sep 4;94(17):1293-300. PMID: 12208894
Article Published Date : Sep 04, 2002
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
Therapeutic Actions : Dietary Modification: Low Glycemic Diet
Problem Substances : Foods: High Glycemic Load
[+]

Regular cola consumption is a modifiable lifestyle that may be associated with pancreatic cancer risk and mortality.Jan 04, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Jan 5 ;15(2). Epub 2023 Jan 5. PMID: 36678146
Article Published Date : Jan 04, 2023
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
Additional Keywords : Risk Factors
Problem Substances : Sugar Sweetened Beverages
[+]

Statin use may increase the risk of pancreatic cancer: Jul 01, 2011

Pubmed Data : Pancreas. 2011 Jul ;40(5):669-72. PMID: 21654539
Article Published Date : Jul 01, 2011
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
Problem Substances : Statin Drugs
[+]

The consumption of folate rich foods (not from supplements) is associated with reduced pancreatic cancer risk. Mar 15, 2006

Pubmed Data : J Natl Cancer Inst. 2006 Mar 15;98(6):407-13. PMID: 16537833
Article Published Date : Mar 15, 2006
Study Type : Human Study
Additional Links
Substances : Folic Acid
Diseases : Pancreatic Cancer
[+]

The consumption of sugar-sweetened soft drinks may be associated with a modest but significant increase in risk of pancreatic cancer among women who have an underlying degree of insulin resistance.Sep 01, 2005

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2098-105. PMID: 16172216
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Pancreatic Cancer
Additional Keywords : Diseases that are Linked
Problem Substances : Sugary soda
[+]

The effects of self-acupressure on pain, fatigue, and sleep quality in colon and pancreatic cancer patients receiving chemotherapy.Jan 15, 2023

Pubmed Data : Cancer Nurs. 2023 Jan 16. Epub 2023 Jan 16. PMID: 36728147
Article Published Date : Jan 15, 2023
Study Type : Human Study
Additional Links
Diseases : Cancer: Fatigue, Colon Cancer, Pancreatic Cancer, Sleep Disorders
Therapeutic Actions : Acupressure
Pharmacological Actions : Chemotherapeutic
[+]

The results of this study suggest that HIFU therapy is safe and has the potential to be a new method of combination therapy for unresectable pancreatic cancer.Jul 27, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2014 Jul 28 ;20(28):9570-7. PMID: 25071354
Article Published Date : Jul 27, 2014
Study Type : Human Study
Additional Links
Diseases : Pancreatic Cancer
Therapeutic Actions : Integrative Medicine, Ultrasound therapy
Pharmacological Actions : Analgesics, Chemotherapeutic
Additional Keywords : Significant Treatment Outcome
[+]

These findings highlight the link between elevated PM2.5 exposure and increased pancreatic cancer risk.Aug 08, 2024

Pubmed Data : Am J Epidemiol. 2024 Aug 9. Epub 2024 Aug 9. PMID: 39123098
Article Published Date : Aug 08, 2024
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Pancreatic Cancer
[+]

These findings provide evidence to support the hypothesis that poor oral hygiene plays an important role in the development of pancreatic cancer.Jul 31, 2015

Pubmed Data : Int J Cancer. 2015 Aug 1. Epub 2015 Aug 1. PMID: 26235255
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Diseases : Dental Plaque, Pancreatic Cancer
Additional Keywords : Increased Risk
[+]

This study provides evidence for a preventive effect of flavonols on pancreatic cancer.Oct 14, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Epidemiol. 2007 Oct 15 ;166(8):924-31. Epub 2007 Aug 9. PMID: 17690219
Article Published Date : Oct 14, 2007
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

Unsaturated fats, and not saturated ones like stearate, may promote pancreatic carcinogenesis. Jul 01, 2009

Pubmed Data : Thromb Res. 2009 Jul;124(3):328-34. Epub 2009 Apr 5. PMID: 2572741
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Substances : Stearic Acid (stearate)
Diseases : Pancreatic Cancer
[+]

Vitamin C and vitamin E mitigate the risk of pancreatic ductal adenocarcinoma from meat-derived mutagen exposure.May 16, 2019

Pubmed Data : J Nutr. 2019 May 17. Epub 2019 May 17. PMID: 31100111
Article Published Date : May 16, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin C, Vitamin E
Diseases : Pancreatic Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Problem Substances : Meat
[+]

Vitamin D may have significant value in the prevention and treatment of pancreatic cancer. - Article 2. Sep 01, 2006

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2006 Sep;15(9):1688-95. PMID: 16985031
Article Published Date : Sep 01, 2006
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Pancreatic Cancer
[+]

Vitamin E and C, selected carotenoids and folate intakes are correlated with a reduced risk for pancreatic cancer.Jun 07, 2010

Pubmed Data : Ann Oncol. 2010 Jun 7. Epub 2010 Jun 7. PMID: 20530201
Article Published Date : Jun 07, 2010
Study Type : Human Study
Additional Links
Substances : Carotenoids, Folate: Dietary, Vitamin C, Vitamin E
Diseases : Pancreatic Cancer
Additional Keywords : Risk Reduction
[+]

Vitamin E taken orally for 2 weeks before pancreatic surgery significantly induced apoptosis in the neoplastic cells of patients with pancreatic ductal neoplasia.Nov 30, 2015

Pubmed Data : EBioMedicine. 2015 Dec ;2(12):1987-95. Epub 2015 Nov 14. PMID: 26844278
Article Published Date : Nov 30, 2015
Study Type : Human Study
Additional Links
Substances : Tocotrienol: Delta, Vitamin E
Diseases : Pancreatic Cancer, Pancreatic Neoplasms
Pharmacological Actions : Apoptotic, Chemopreventive
Additional Keywords : Significant Treatment Outcome
[+]

A diet rich in sulforaphane and related mustard oils may be considered as a supportive nutritional strategy to enhance therapeutic efficacy in patients suffering from pancreatic cancer.Mar 29, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2014 Mar 30 ;5(6):1621-34. PMID: 24742583
Article Published Date : Mar 29, 2014
Study Type : Human In Vitro
Additional Links
Substances : Cruciferous Vegetables, Sulforaphane
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemotherapeutic
Additional Keywords : Cancer Stem Cells, Dietary Concentrations
[+]

Apigenin highly upregulated the expression of cytokine genes and induced apoptosis in human pancreatic cancer cells.Nov 30, 2013

Pubmed Data : Mol Nutr Food Res. 2013 Dec ;57(12):2112-27. Epub 2013 Aug 14. PMID: 23943362
Article Published Date : Nov 30, 2013
Study Type : Human In Vitro
Additional Links
Substances : Apigenin, Flavonoids
Diseases : Inflammation, Pancreatic Cancer
Pharmacological Actions : Anti Inflammatory, Antiproliferative , Apoptotic, Cell cycle arrest, Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor, NF-kappaB Inhibitor
Additional Keywords : Epigenetic Modification In Cancer
[+]

Dandelion root induces selective apoptosis and autophagy in human pancreatic cancer cells in a dose and time dependent manner.Sep 30, 2012

Pubmed Data : Pancreas. 2012 Oct ;41(7):1039-47. PMID: 22647733
Article Published Date : Sep 30, 2012
Study Type : Human In Vitro
Additional Links
Substances : Dandelion
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
Additional Keywords : Selective Cytotoxicity
[+]

Inhibition of oncoprotein cell division cycle 20 by curcumin could be useful for the treatment of pancreatic cancer.Feb 03, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Feb 4 ;9(2). Epub 2017 Feb 4. PMID: 28165402
Article Published Date : Feb 03, 2017
Study Type : Human In Vitro
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Naringenin causes ASK1-induced apoptosis via reactive oxygen species in human pancreatic cancer cells.Nov 08, 2016

Pubmed Data : Food Chem Toxicol. 2016 Nov 9. Epub 2016 Aug 9. PMID: 27838343
Article Published Date : Nov 08, 2016
Study Type : Human In Vitro
Additional Links
Substances : Naringenin
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Tumor Suppressor Protein p53 Upregulation
[+]

Spirulina platensis and related tetrapyrroles have potent antiproliferative effects on experimental human pancreatic cancer.Feb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Hepatol. 2014 Mar-Apr;13(2):273-83. PMID: 24552870
Article Published Date : Feb 28, 2014
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Spirulina
Diseases : Pancreatic Cancer
Pharmacological Actions : Antioxidant, Antiproliferative , Chemopreventive, MicroRNA modulator
Additional Keywords : Tetrapyrrolic Compounds
[+]

The results showed that 105 miRNAs were significantly differentially in oridonin-treated BxPC-3 human pancreatic cancer cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 ;15:117. Epub 2015 Apr 14. PMID: 25880988
Article Published Date : Dec 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Oridonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, MicroRNA modulator
[+]

Thymoquinone promotes pancreatic cancer cell death and reduction of tumor size.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Prev Med. 2016 ;2016:1407840. Epub 2016 Dec 26. PMID: 28105374
Article Published Date : Dec 31, 2015
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Thymoquinone
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest, Histone deacetylase inhibitor, P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Dose Response
[+]

Zerumbone was able to induce apoptosis of pancreatic carcinoma cell lines Jan 01, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2012 ;2012:936030. Epub 2012 Jan 29. PMID: 22454691
Article Published Date : Jan 01, 2012
Study Type : Human In Vitro
Additional Links
Substances : Ginger, Zerumbone
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Zerumbone
[+]

Berbamine exerts an anti-oncogenic effect on pancreatic cancer.May 08, 2022

Pubmed Data : Anticancer Agents Med Chem. 2022 May 9. Epub 2022 May 9. PMID: 35579129
Article Published Date : May 08, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Berbamine
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Betulinic acid-mediating miRNA-365 inhibited the progression of pancreatic cancer.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Res. 2023 ;31(4):505-514. Epub 2023 Jun 27. PMID: 37415745
Article Published Date : Dec 31, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Apoptotic, Interleukin-6 Downregulation
[+]

Cannabidiol's cytotoxicity in pancreatic cancer is induced via an upregulation of ceramide synthase 1 and ER stress.May 07, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cannabis Res. 2024 May 8 ;6(1):22. Epub 2024 May 8. PMID: 38720356
Article Published Date : May 07, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Chemotherapeutic
[+]

Celastrol suppresses human pancreatic cancer via m6A-YTHDF3-mediated downregulation of Claspin and Bcl-2.Dec 17, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Discov Oncol. 2023 Dec 18 ;14(1):233. Epub 2023 Dec 18. PMID: 38110764
Article Published Date : Dec 17, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Celastrol
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Chrysin induces autophagy-dependent ferroptosis to increase chemosensitivity to gemcitabine by targeting CBR1 in pancreatic cancer cells.Jan 10, 2021

Pubmed Data : Biochem Pharmacol. 2021 11 ;193:114813. Epub 2021 Oct 18. PMID: 34673014
Article Published Date : Jan 10, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chrysin
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Chrysin-induced G protein-coupled estrogen receptor activation suppresses pancreatic cancer.Aug 25, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Aug 26 ;23(17). Epub 2022 Aug 26. PMID: 36077069
Article Published Date : Aug 25, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chrysin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer.Apr 30, 2012

Pubmed Data : J Cancer Res Clin Oncol. 2012 May ;138(5):785-97. Epub 2012 Jan 24. PMID: 22270965
Article Published Date : Apr 30, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Horse Chestnut
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Apoptotic, Antiproliferative , NF-kappaB Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer.Oct 29, 2023

Pubmed Data : BMC Cancer. 2023 Oct 30 ;23(1):1044. Epub 2023 Oct 30. PMID: 37904102
Article Published Date : Oct 29, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lactobacillus casei, Lactobacillus reuteri
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]

Long-term survival of a patient with advanced pancreatic cancer under adjunct treatment with Viscum album extracts: A case report.Mar 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2019 Mar 28 ;25(12):1524-1530. PMID: 30948915
Article Published Date : Mar 27, 2019
Study Type : Human: Case Report
Additional Links
Substances : Mistletoe
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemotherapeutic, Immunostimulatory
Additional Keywords : Drug: 5-flourouracil., Plant Extracts
[+]

One of three enrolled patients with advanced stomach cancer had no evidence of disease progression for 36 months while taking noni.Dec 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diet Suppl. 2009 ;6(4):347-59. PMID: 22435516
Article Published Date : Dec 31, 2008
Study Type : Human: Case Report
Additional Links
Substances : Noni
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Tumor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Spontaneous regression in solid pseudopapillary neoplasm of pancreas.Jan 31, 2023

Pubmed Data : Clin J Gastroenterol. 2023 Feb ;16(1):105-109. Epub 2022 Oct 10. PMID: 36214971
Article Published Date : Jan 31, 2023
Study Type : Human: Case Report
Additional Links
Diseases : Pancreatic Cancer
Additional Keywords : Spontaneous Tumor Regression
[+]

Spontaneous regression of pancreatic cancer with liver metastases.May 30, 2019

Pubmed Data : BMJ Case Rep. 2019 May 31 ;12(5). Epub 2019 May 31. PMID: 31154349
Article Published Date : May 30, 2019
Study Type : Human: Case Report
Additional Links
Diseases : Cancer Metastasis, Pancreatic Cancer
Additional Keywords : Spontaneous Tumor Regression
[+]

Spontaneous regression of pancreatic cancer.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Surg Case Rep. 2018 ;42:55-59. Epub 2017 Dec 2. PMID: 29216532
Article Published Date : Dec 31, 2017
Study Type : Human: Case Report, Review
Additional Links
Diseases : Pancreatic Cancer
Additional Keywords : Spontaneous Regression
[+]

Treatment of pancreatic cancer with intravenous vitamin C.Feb 11, 2018

Pubmed Data : Anticancer Drugs. 2018 Feb 12. Epub 2018 Feb 12. PMID: 29438178
Article Published Date : Feb 11, 2018
Study Type : Human: Case Report
Additional Links
Substances : Vitamin C: Intravenous
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
[+]

Ursolic acid restores sensitivity to gemcitabine.Jan 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Food Drug Anal. 2021 06 15 ;29(2):262-274. Epub 2021 Jun 15. PMID: 35696208
Article Published Date : Jan 14, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ursolic Acid
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemosensitizer, NF-kappaB Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Oridonin inhibition and miR‑200b‑3p/ZEB1 axis in human pancreatic cancer.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2017 Jan ;50(1):111-120. Epub 2016 Nov 18. PMID: 27878247
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , MicroRNA modulator
[+]

A combination of cucurbitacin B and gemcitabine had profound anti-proliferative effects in vivo against pancreatic cancer cells.May 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2010 Jun ;160(4):998-1007. PMID: 20590594
Article Published Date : May 31, 2010
Study Type : Animal Study
Additional Links
Substances : Cucurbitacin B
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

A high omega-3 fatty acid diet mitigates pancreatic precancer development in a mouse experimental model. May 15, 2009

Pubmed Data : J Surg Res. 2009 May 15. PMID: 19631339
Article Published Date : May 15, 2009
Study Type : Animal Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Pancreatic Cancer
[+]

A ketogenic diet in combination with gemcitabine mitigates pancreatic cancer-associated c.achexia.Jun 27, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Jun 28 ;24(13). Epub 2023 Jun 28. PMID: 37445930
Article Published Date : Jun 27, 2023
Study Type : Animal Study
Additional Links
Diseases : Cachexia: Cancer, Pancreatic Cancer
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Anti-Cachexic Agents
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

A Western-style diet induced pancreatic epithelial cell hyperproliferation in mice, further suggesting that increased fat content and decreased calcium and vitamin D contribute to the development of pancreatic neoplasms.Nov 06, 1996

Pubmed Data : J Natl Cancer Inst. 1996 Nov 6;88(21):1586-90. PMID: 8901857
Article Published Date : Nov 06, 1996
Study Type : Animal Study
Additional Links
Substances : Calcium, Vitamin D
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
Anti Therapeutic Actions : Western Diet
[+]

Alpha-lipoic acid strongly reduced AgNP-induced side effects without weakening the therapeutic efficacy.Sep 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2021 Sep 24 ;13(19). Epub 2021 Sep 24. PMID: 34638256
Article Published Date : Sep 23, 2021
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid, Silver (nanoparticles)
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Chemotherapeutic
Additional Keywords : Natural Substance Synergy
[+]

An antioxidant-rich extract of seaweed polyphenols combined with current PC treatment modalities may inhibit tumor relapse by targeting therapy-orchestrated autophagy in residual cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biomed Sci. 2015 ;22(1):28. Epub 2015 Apr 17. PMID: 25898131
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Polyphenols, Seaweed
Diseases : Cancers: Drug Resistant, Cancers: Radiation-Resistant, Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Autophagy Inhibitors, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine, Gene Expression Regulation, Significant Treatment Outcome
[+]

Anticancer activity of aqueous fenugreek seed extract against pancreatic cancer, histological evidence.Aug 31, 2021

Pubmed Data : J Gastrointest Cancer. 2021 Sep 1. Epub 2021 Sep 1. PMID: 34472011
Article Published Date : Aug 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fenugreek
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Antitumor effect of human lactoferrin against newly established human pancreatic cancer cell line SPA.Jul 31, 1998

Pubmed Data : Gan To Kagaku Ryoho. 1998 Aug ;25(10):1557-63. PMID: 9725049
Article Published Date : Jul 31, 1998
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lactoferrin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative
[+]

Antitumor effects of cannabinoids in human pancreatic ductal adenocarcinoma cell line.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Vet Sci. 2022 ;9:867575. Epub 2022 Jul 22. PMID: 35937289
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Cannabinoids
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Apigenin enhances the anti-tumor effect of gemcitabine. Jan 18, 2008

Pubmed Data : Cancer Lett. 2008 Jan 18;259(1):39-49. Epub 2007 Oct 29. PMID: 17967505
Article Published Date : Jan 18, 2008
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, NF-kappaB Inhibitor
Additional Keywords : Drug: Gemcitabine, Drug-Plant-Vitamin Synergies
[+]

Apigenin may be a therapeutic agent for stabilizing Ikaros expression and function to maintain T cell homeostasis in murine pancreatic cancer.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(2):e0170197. Epub 2017 Feb 2. PMID: 28152014
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemotherapeutic, Immunomodulatory
[+]

Artesunate, a novel derivative of artemisin, has in vitro and in vivo anticancer activity against pancreatic cancer. It exhibits selective cytotoxicity and has in vivo antitumor activity similar to that of gemcitabine.Apr 01, 2010

Pubmed Data : Cancer Chemother Pharmacol. 2010 Apr;65(5):895-902. Epub 2009 Aug 19. PMID: 19690861
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Artemisinin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
Additional Keywords : Drug: Gemcitabine, Selective Cytotoxicity, Superiority of Natural Substances versus Drugs
[+]

Ascorbate combined with ionizing radiation decreased tumor growth and increased survival, without damaging the gastrointestinal tract.Jun 15, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Res. 2015 Jun 16. Epub 2015 Jun 16. PMID: 26081808
Article Published Date : Jun 15, 2015
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Pancreatic Cancer
Pharmacological Actions : Radioprotective, Radiosensitizer
Additional Keywords : Selective Cytotoxicity
[+]

Astaxanthin inhibits gemcitabine-resistant human pancreatic cancer progressionOct 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Nov ;14(5):5400-5408. Epub 2017 Aug 28. PMID: 29098031
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Baicalein could increase caspase-3 and Bax expression and decrease survivin and Bcl-2 to induce apoptosis.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pancreas. 2017 Sep ;46(8):1076-1081. PMID: 28787336
Article Published Date : Aug 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Baicalein
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Caspase-3 Activation, Survivin Down-Regulation
[+]

Benzyl isothiocyanate and sulforaphane protect against initiation of pancreatic carcinogenesis in hamsters.Sep 28, 2006

Pubmed Data : Cancer Lett. 2006 Sep 28;241(2):275-80. Epub 2006 Jan 4. PMID: 16386831
Article Published Date : Sep 28, 2006
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate , Sulforaphane
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive, Cyclooxygenase 2 Inhibitors
Additional Keywords : Isothiocyanates, Stilbenes
[+]

Boswellic acid suppresses growth and metastatis of human pancreatic tumors (nude mouse model). Jan 01, 2011

Pubmed Data : PLoS One. 2011 ;6(10):e26943. Epub 2011 Oct 31. PMID: 22066019
Article Published Date : Jan 01, 2011
Study Type : Transgenic Animal Study
Additional Links
Substances : Boswellia
Diseases : Cancer Metastasis, Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Bromelain and acetylcysteine alone and in combination with gemcitabine inhibit subcutaneous deposits of pancreatic cancer after intraperitoneal injection.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2021 ;13(12):13524-13539. Epub 2021 Dec 15. PMID: 35035694
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Bromelain, NAC (N-acetyl-L-cysteine)
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Capsaicin is an effective inhibitor of in vitro and in vivo growth of pancreatic cancer cells. Dec 01, 2008

Pubmed Data : Apoptosis. 2008 Dec;13(12):1465-78. PMID: 19002586
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Cayenne
Diseases : Pancreatic Cancer
[+]

Capsaicin significantly reduced the severity of chronic pancreatitis in mice. Oct 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Carcinogenesis. 2011 Nov ;32(11):1689-96. Epub 2011 Aug 22. PMID: 21859833
Article Published Date : Oct 31, 2011
Study Type : Animal Study
Additional Links
Substances : Capsaicin
Diseases : Pancreatic Cancer, Pancreatitis
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

Combination of two or three components showed striking synergetic effect with gemcitabine in vitro.Jan 11, 2017

Pubmed Data : Cancer Lett. 2017 Jan 12. Epub 2017 Jan 12. PMID: 28089829
Article Published Date : Jan 11, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Capsaicin, Piceatannol , Resveratrol, Sulforaphane
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine, Natural Substance Synergy
[+]

Combined treatment with naringenin and hesperetin might be a promising anti-cancer strategy for pancreatic cancers.Nov 19, 2018

Pubmed Data : Phytomedicine. 2018 Nov 20 ;58:152762. Epub 2018 Nov 20. PMID: 31005717
Article Published Date : Nov 19, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Hesperidin, Naringenin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Selective Antiproliferation
[+]

Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Dis. 2016 ;7(6):e2246. Epub 2016 Jun 2. PMID: 27253410
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Quercetin, Sulforaphane
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Cordycepin inhibits pancreatic cancer cell growth.Apr 30, 2020

Pubmed Data : Chin J Nat Med. 2020 May ;18(5):345-355. PMID: 32451092
Article Published Date : Apr 30, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Cucurbitacin B suppresses proliferation of pancreatic cancer cells.Sep 11, 2018

Pubmed Data : J Cell Physiol. 2018 Sep 12. Epub 2018 Sep 12. PMID: 30206930
Article Published Date : Sep 11, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , MicroRNA modulator
[+]

Cucurbitacin B, a compound found within plants such as Bitter Apple, potentials the effect of gemcitabine and has profound antiproliferative effects against pancreatic cancer cell lines, in vitro and in vivo. Jul 15, 2009

Pubmed Data : Cancer Res. 2009 Jul 15;69(14):5876-84. PMID: 19605406
Article Published Date : Jul 15, 2009
Study Type : Animal Study
Additional Links
Substances : Bitter Apple
Diseases : Pancreatic Cancer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Curcumin and omega-3 fatty acids provide synergistic pancreatic tumor inhibitory properties in a mouse experimental model. Jan 01, 2008

Pubmed Data : Nutr Cancer. 2008;60 Suppl 1:81-9. PMID: 19003584
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin, Omega-3 Fatty Acids
Diseases : Pancreatic Cancer
[+]

Curcumin inhibits the growth of pancreatic cancer in a mouse experimental model. Jun 01, 2009

Pubmed Data : Anticancer Res. 2009 Jun;29(6):1895-9. PMID: 19528445
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
[+]

Curcumin potentiates the activity of the chemotherapy agent gemcitabine in vitro and in vivo animal models of pancreatic cancer. Apr 15, 2007

Pubmed Data : Cancer Res. 2007 Apr 15;67(8):3853-61. PMID: 17440100
Article Published Date : Apr 15, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine, Drug-Plant-Vitamin Synergies
[+]

Curcumol inhibits the growth of xenograft-tumors in mice and the biological activities of pancreatic cancer cells.May 31, 2022

Pubmed Data : Cell Cycle. 2022 Jun ;21(12):1249-1266. Epub 2022 Mar 6. PMID: 35253605
Article Published Date : May 31, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumol
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , MicroRNA modulator
[+]

Dietary crocin is protective in pancreatic cancer while reducing radiation-induced hepatic oxidative damage.Jan 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 06 26 ;12(6). Epub 2020 Jun 26. PMID: 32604971
Article Published Date : Jan 25, 2020
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Liver Damage, Pancreatic Cancer, Radiation
Pharmacological Actions : Radioprotective
[+]

Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis.Aug 31, 2013

Pubmed Data : Anticancer Res. 2013 Sep ;33(9):3603-9. PMID: 24023285
Article Published Date : Aug 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin, Curcumin: Lipidated
Diseases : Pancreatic Cancer, Pancreatic Cancer: Metastatic
Pharmacological Actions : Anti-metastatic
[+]

EGCG is a strong combination partner of gemcitabine reducing pancreatic cancer cell growth by suppressing glycolysis.Oct 04, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2019 Oct 5 ;11(10). Epub 2019 Oct 5. PMID: 31590367
Article Published Date : Oct 04, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer
Additional Keywords : Cancer Glycolysis, Chemotherapeutic Synergy: Gemcitabine
[+]

EGCG, a green tea polyphenol, inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer in vivo. Jan 01, 2008

Pubmed Data : Front Biosci. 2008 Jan 1;13:440-52. PMID: 17981559
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Green Tea
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Angiogenic
[+]

Emodin alleviates gemcitabine resistance in pancreatic cancer.Oct 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2020 Nov ;20(5):167. Epub 2020 Aug 27. PMID: 32934734
Article Published Date : Oct 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Emodin
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Chemosensitizer
[+]

Emodin exerts anti-metastatic activity in pancreatic cancer both in vitro and in vivo. Nov 01, 2011

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2011 Nov ;36(22):3167-71. PMID: 22375400
Article Published Date : Nov 01, 2011
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Cancer Metastasis, Pancreatic Cancer, Pancreatic Cancer: Metastatic
Pharmacological Actions : Anti-Angiogenic, Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor
[+]

Emodin reverses resistance to gemcitabine in pancreatic cancer.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2023 Jan ;25(1):7. Epub 2022 Nov 16. PMID: 36545274
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Emodin sensitizes human pancreatic cancer cells to EGFR inhibitor through suppressing Stat3 signaling pathway.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Manag Res. 2019 ;11:8463-8473. Epub 2019 Sep 17. PMID: 31572001
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Emodin
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic
[+]

Epigallocatechin-3-gallate decreases hypoxia-inducible factor-1 in pancreatic cancer cells. Mar 02, 2023

Pubmed Data : Am J Chin Med. 2023 Mar 3:1-17. Epub 2023 Mar 3. PMID: 36867109
Article Published Date : Mar 02, 2023
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Pancreatic Cancer
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
[+]

Fermented extraction of citrus unshiu peel inhibits viability and migration of human pancreatic cancers.Dec 31, 2017

Pubmed Data : J Med Food. 2018 Jan ;21(1):5-12. PMID: 29346059
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Citrus Peel , Fermented Foods and Beverages
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

Frankincense essential oil from Boswellia sacra is capable of suppressing viability and inducing apoptosis in pancreatic cancer cell lines.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2012 ;12:253. Epub 2012 Dec 13. PMID: 23237355
Article Published Date : Dec 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

Fucoxanthin prevents pancreatic tumorigenesis in C57BL/6J mice.Dec 18, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Dec 19 ;22(24). Epub 2021 Dec 19. PMID: 34948416
Article Published Date : Dec 18, 2021
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
[+]

Genistein may act as a chemosensitizer and synergist in the treatment of pancreatic cancer with gemcitabine. Oct 01, 2005

Pubmed Data : Cancer Res. 2005 Oct 1;65(19):9064-72. PMID: 16204081
Article Published Date : Oct 01, 2005
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor
Additional Keywords : Drug: Gemcitabine, Drug-Plant-Vitamin Synergies
[+]

Ginger extract inhibited cell proliferation and subsequently induced the autotic death of pancreatic cancer Panc-1 cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(5):e0126605. Epub 2015 May 11. PMID: 25961833
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : 6-Shogaol, Ginger, Gingerol
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Autophagy Up-regulation
[+]

Ginkgolic acid reduced the expression of the key enzymes involved in lipogenesis and restrained the tumor growth.Mar 25, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2015 Mar 26. Epub 2015 Mar 26. PMID: 25895130
Article Published Date : Mar 25, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginkgo biloba
Diseases : Pancreatic Cancer, Pancreatic Cancer: Metastatic
Pharmacological Actions : Anti-metastatic, Anticarcinogenic Agents, Antiproliferative , Chemopreventive
[+]

Ginsenoside Rg3 could enhance the efficacy of erlotinib to inhibit the proliferation of pancreatic cancer cells.Oct 12, 2017

Pubmed Data : Biomed Pharmacother. 2017 Oct 13 ;96:619-625. Epub 2017 Oct 13. PMID: 29035827
Article Published Date : Oct 12, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Erlotinib
[+]

Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer.Aug 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2014 Sep ;45(3):1065-72. Epub 2014 Jun 16. PMID: 24938458
Article Published Date : Aug 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Grape proanthocyanidin inhibit pancreatic cancer cell growth in vitro and in vivo.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(8):e43064. Epub 2012 Aug 8. PMID: 22905202
Article Published Date : Dec 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Grape Seed Extract
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest
Additional Keywords : Plant Extracts, Proanthocyanidins
[+]

Harmines inhibit cancer cell growth through coordinated activation of apoptosis and inhibition of autophagy.Jan 24, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 03 25 ;498(1):99-104. Epub 2018 Mar 1. PMID: 29501493
Article Published Date : Jan 24, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Psychedelics:All
Diseases : Bone Cancer, Breast Cancer, Lung Cancer, Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Inhibitors, Cell cycle arrest
Additional Keywords : Selective Cytotoxicity
[+]

Indole-3-carbinol would be effective for enhancing sensitivity of pancreatic cancer cells to gemcitabine.Mar 31, 2013

Pubmed Data : Anticancer Res. 2013 Apr ;33(4):1473-81. PMID: 23564788
Article Published Date : Mar 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Leaf extracts of both M.charantia and O.basilicum will serve as a measure against induced pancreatic cancer.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2018 Apr ;8(2):282-288. Epub 2017 May 3. PMID: 29736383
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Basil, Bitter Melon
Diseases : Pancreatic Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

Magnolol suppresses pancreatic cancer development.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2020 ;10:597672. Epub 2020 Dec 2. PMID: 33344246
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Magnolol
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive, Transforming growth factor beta (TGF-β) inhibitor
[+]

Matrine, an alkaloid extracted from a Chinese herb, Sophora flavescens inhibits the proliferation of pancreatic cancer cells.Jan 01, 2010

Pubmed Data : Biol Pharm Bull. 2010;33(10):1740-5. PMID: 20930385
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Sophora Flavescens
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Proliferative, Apoptotic
[+]

Melatonin may offer an adjunct therapy in the treatment of pancreatic cancer.Oct 01, 2007

Pubmed Data : J Pineal Res. 2007 Oct;43(3):270-5. PMID: 17803524
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Pancreatic Cancer
[+]

Mimosine, an amino acid extracted from Mimosa pudica, induces programmed cell death and suppresses growth in human pancreatic cancer in animal model. Sep 01, 2003

Pubmed Data : Anticancer Res. 2003 Sep-Oct;23(5A):4007-9. PMID:14666710
Article Published Date : Sep 01, 2003
Study Type : Transgenic Animal Study
Additional Links
Substances : Mimosa pudica
Diseases : Pancreatic Cancer
[+]

Obesity potentiates the growth and dissemination of pancreatic cancer.Jul 31, 2009

Pubmed Data : Surgery. 2009 Aug ;146(2):258-63. PMID: 19628082
Article Published Date : Jul 31, 2009
Study Type : Animal Study
Additional Links
Diseases : Cancer Metastasis, Pancreatic Cancer
Anti Therapeutic Actions : Overnutrition
Adverse Pharmacological Actions : Carcinogenic
[+]

Omega 6 fatty acids stimulate tumor growth, whereas omega 3 fatty acids inhibit pancreatic tumor growth. May 01, 2008

Pubmed Data : Pancreas. 2008 May;36(4):353-62. PMID: 18437081
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Pancreatic Cancer
Additional Keywords : Omega 3/6 Ratio, Omega 6 Fatty Acids are Detrimental
[+]

Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Cell Int. 2016 ;16:57. Epub 2016 Jul 22. PMID: 27453691
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Wnt/β-catenin signaling pathway modulation
[+]

Our study represents the first comprehensive preclinical evaluation of the activity of natural vitamin E compounds in pancreatic cancer.Nov 30, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Cancer Ther. 2011 Dec ;10(12):2363-72. Epub 2011 Oct 4. PMID: 21971120
Article Published Date : Nov 30, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tocotrienol: Delta, Vitamin E
Diseases : Pancreatic Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , NF-kappaB Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.Jun 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Jun 28. Epub 2017 Jun 28. PMID: 28711943
Article Published Date : Jun 27, 2017
Study Type : Animal Study
Additional Links
Diseases : Cancer Metastasis, Pancreatic Cancer
Additional Keywords : Exosomes
[+]

Piperlongumine potentiates the effects of gemcitabine in in vitro and in vivo human pancreatic cancer models.Feb 12, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2018 Feb 13 ;9(12):10457-10469. Epub 2017 Dec 23. PMID: 29535819
Article Published Date : Feb 12, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Piperlongumine suppresses growth and sensitizes pancreatic tumors to gemcitabine in a xenograft mouse model.Dec 13, 2015

Pubmed Data : Cancer Prev Res (Phila). 2015 Dec 14. Epub 2015 Dec 14. PMID: 26667450
Article Published Date : Dec 13, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Long Pepper
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Bcl-2 protein down-regulation, Chemosensitizer, Cyclin D1 Down-Regulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor, Survivin Down-Regulation, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Porcine pancreatic extract has a potential to inhibit pancreatic cancer growthAug 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JOP. 2012 Sep ;13(5):482-7. Epub 2012 Sep 10. PMID: 22964954
Article Published Date : Aug 31, 2012
Study Type : Animal Study
Additional Links
Substances : Pancreatic Enzymes
Diseases : Pancreatic Cancer
[+]

Pretreatment with 6-shogaol resulted in an inhibition of constitutive and gemcitabine induced NF-κB activity and exerted its chemosensitization effects to gemcitabine.Feb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AAPS J. 2014 Mar ;16(2):246-57. Epub 2014 Jan 15. PMID: 24424498
Article Published Date : Feb 28, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : 6-Shogaol
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemotherapeutic, NF-kappaB Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Pterostilbene decreases the antioxidant defenses of aggressive cancer cells in vivoDec 08, 2015

Pubmed Data : Antioxid Redox Signal. 2015 Dec 9. Epub 2015 Dec 9. PMID: 26651028
Article Published Date : Dec 08, 2015
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Melanoma, Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Quercetin enhances the anti-tumor effects of BET inhibitors by suppressing hnRNPA1.Sep 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Sep 2 ;20(17). Epub 2019 Sep 2. PMID: 31480735
Article Published Date : Sep 01, 2019
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Resveratrol, a multi-targeted agent, can enhance antitumor activity of gemcitabine in a mouse model of human pancreatic cancer.Nov 11, 2009

Pubmed Data : Int J Cancer. 2009 Nov 11. PMID: 19908231
Article Published Date : Nov 11, 2009
Study Type : Transgenic Animal Study
Additional Links
Substances : Resveratrol
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine, Drug-Plant-Vitamin Synergies
[+]

Sea cucumber contains a compound Frondoside A which has potent growth inhibitory effects against human pancreatic cancer cells.Sep 01, 2008

Pubmed Data : Ann N Y Acad Sci. 2008 Sep;1138:181-98. PMID: 18837899
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Sea Cucumber
Diseases : Pancreatic Cancer
[+]

Seaweed polyphenols may inhibit pancreatic cancer relapse/recurrence by targeting therapy-orchestrated stem-cell signaling in residual cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Stem Cell Res Ther. 2015 ;6(1):182. Epub 2015 Sep 22. PMID: 26395574
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Polyphenols, Seaweed: Brown
Diseases : Pancreatic Cancer
Pharmacological Actions : Radiosensitizer
Additional Keywords : Cancer Stem Cells
[+]

Selenium induces pancreatic cancer cell death alone and in combination with gemcitabine.Jan 10, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicines. 2022 Jan 11 ;10(1). Epub 2022 Jan 11. PMID: 35052828
Article Published Date : Jan 10, 2022
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Shikonin inhibited immune evasion in pancreatic cancer by inhibiting PD-L1 glycosylation.Mar 31, 2021

Pubmed Data : Pancreatology. 2021 Apr ;21(3):630-641. Epub 2021 Feb 12. PMID: 33707115
Article Published Date : Mar 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Immunomodulatory
[+]

Silibinin-induced metabolic reprogramming diminishes cell growth and cachectic properties of pancreatic cancer cells and in animal models.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2015 Dec 1 ;6(38):41146-61. PMID: 26510913
Article Published Date : Nov 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Silibinin
Diseases : Cachexia: Cancer, Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Dose Response
[+]

Sulforaphane enhances the anticancer activity of a chemo-agent against pancreatic cancer. Aug 29, 2011

Pubmed Data : Nutr Cancer. 2011 Aug 29. Epub 2011 Aug 29. PMID: 21875325
Article Published Date : Aug 29, 2011
Study Type : Transgenic Animal Study
Additional Links
Substances : Broccoli, Sprouts, Sulforaphane
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Drug Synergy
[+]

Sulforaphane increases the effectiveness of various cytotoxic drugs against pancreatic cancer stem cells without inducing additional toxicity in mice.Jun 01, 2004

Pubmed Data : J Med Food. 2004 Summer;7(2):157-61. PMID: 20940707
Article Published Date : Jun 01, 2004
Study Type : Transgenic Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Cancers: Multi-Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Sulforaphane induces miR135b-5p and its target gene to inhibit the progression of pancreatic cancer.Sep 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Ther Oncolytics. 2019 Sep 27 ;14:74-81. Epub 2019 Apr 6. PMID: 31044154
Article Published Date : Sep 26, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , MicroRNA modulator
[+]

Sulforaphane inhibits pancreatic cancer proliferation through AMPK activation and Nrf2 translocation in vitro and in vivo.Jan 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2018 ;50(3):1201-1215. Epub 2018 Oct 24. PMID: 30355942
Article Published Date : Jan 01, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Tumor, Anticarcinogenic Agents, Antiproliferative , Apoptotic, Nrf2 activation
Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates
[+]

Sulforaphane may do more than prevent cancer, but actively treat established pancreatic cancer.Oct 01, 2004

Pubmed Data : Mol Cancer Ther. 2004 Oct;3(10):1239-48. PMID: 15486191
Article Published Date : Oct 01, 2004
Study Type : Animal Study
Additional Links
Substances : Broccoli
Diseases : Pancreatic Cancer
[+]

Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.Aug 01, 2010

Pubmed Data : Mol Cancer Ther. 2010 Aug;9(8):2255-64. Epub 2010 Jul 20. PMID: 20647339
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, NF-kappaB Inhibitor
Additional Keywords : Drug Synergy
[+]

The present results demonstrate that oridonin overcomes PANC-1/Gem cells gemcitabine reistance.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2019 ;12:5751-5765. Epub 2019 Jul 17. PMID: 31410021
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

The soy isoflavone genistein potentiates the antitumor activity of cisplatin against pancreatic tumors in an animal model. Mar 15, 2006

Pubmed Data : Cancer. 2006 Mar 15;106(6):1260-8. PMID: 16475211
Article Published Date : Mar 15, 2006
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Pancreatic Cancer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Drug-Plant-Vitamin Synergies
[+]

The synergic inhibitory effects of dark tea extract and p38 inhibition on the growth of pancreatic cancer cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer. 2019 ;10(26):6557-6569. Epub 2019 Oct 21. PMID: 31777585
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Black Tea
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Chemotherapeutic
[+]

The traditional Ayurvedic formula known as triphala inhibits pancreatic cancer cell growth in vitro and in vivo. Oct 10, 2008

Pubmed Data : BMC Cancer. 2008 Oct 10;8:294. PMID: 18847491
Article Published Date : Oct 10, 2008
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Pancreatic Cancer
[+]

These findings indicate that Paeonia suffruticosa may constitute a potential new alternative or complementary medicine for pancreatic cancer.Jul 14, 2018

Pubmed Data : Phytomedicine. 2018 Jul 15 ;46:184-192. Epub 2018 Mar 27. PMID: 30097117
Article Published Date : Jul 14, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Peony
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation
Additional Keywords : Plant Extracts
[+]

These results suggest that the combination of SK and gemcitabine may be a promising chemotherapy regimen for pancreatic cancer.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2017 ;9(12):5507-5517. Epub 2017 Dec 15. PMID: 29312502
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression.Aug 17, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : iScience. 2023 Aug 18 ;26(8):107408. Epub 2023 Jul 17. PMID: 37554459
Article Published Date : Aug 17, 2023
Study Type : Animal Study
Additional Links
Substances : Tomatidine
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Toxicological studies of Orthosiphon stamineus standardized ethanol extract in combination with gemcitabine.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Adv Res. 2019 Jan ;15:59-68. Epub 2018 May 9. PMID: 30581613
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Orthosiphon
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Treatment with emodin may repress angiogenesis in pancreatic cancer by altering the activities of the TGF-β/Smad pathway and angiogenesis-associated microRNAs. Jul 30, 2015

Pubmed Data : Mol Med Rep. 2015 Jul 31. Epub 2015 Jul 31. PMID: 26238071
Article Published Date : Jul 30, 2015
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Pancreatic Cancer
Pharmacological Actions : Angiogenesis Inhibitors, MicroRNA modulator
[+]

Treatment with pancreatic enzymes significantly prolongs the survival of mice with human pancreatic cancer xenografts and slows the tumor growth.May 01, 2004

Pubmed Data : Pancreas. 2004 May;28(4):401-12. PMID: 15097858
Article Published Date : May 01, 2004
Study Type : Animal Study
Additional Links
Substances : Pancreatic Enzymes
Diseases : Pancreatic Cancer
[+]

Withaferin-A, a compound found within Ashwaganda, exhibits in vivo anticancer activity against pancreatic cancer. Feb 15, 2010

Pubmed Data : Biochem Pharmacol. 2010 Feb 15;79(4):542-51. PMID: 19769945
Article Published Date : Feb 15, 2010
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Pancreatic Cancer
[+]

Wogonin increases gemcitabine sensitivity in pancreatic cancer by inhibiting Akt pathway.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:1068855. Epub 2022 Dec 23. PMID: 36618921
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Xanthohumol could be a promising therapeutic agent against human pancreatic cancer.Jun 30, 2015

Pubmed Data : Biomed Pharmacother. 2015 Jul ;73:40-7. Epub 2015 Jun 4. PMID: 26211581
Article Published Date : Jun 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, MicroRNA modulator
[+]

Zyflamend exhibits anticancer properties in mice bearing pancreatic cancer cells.Mar 01, 2012

Pubmed Data : Antioxid Redox Signal. 2012 Mar 1 ;16(5):413-27. Epub 2011 Dec 15. PMID: 22004570
Article Published Date : Mar 01, 2012
Study Type : Animal Study
Additional Links
Substances : Zyflamend
Diseases : Pancreatic Cancer
Pharmacological Actions : Death receptor up-regulation, Survival protein down-regulation, TRAIL sensitizer
[+]

Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model. Sep 20, 2011

Pubmed Data : Int J Cancer. 2011 Sep 20. Epub 2011 Sep 20. PMID: 21935918
Article Published Date : Sep 20, 2011
Study Type : Transgenic Animal Study
Additional Links
Substances : Zyflamend
Diseases : Pancreatic Cancer
[+]

α-mangostin suppressed the proliferation, migration, and invasion of pancreatic cancer cells.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2014 ;2014:546353. Epub 2014 Apr 10. PMID: 24812621
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Mangosteen
Diseases : Pancreatic Cancer, Pancreatic Cancer: Metastatic
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest, PI3K/Akt/signaling suppression
[+]

Chemovirotherapy for pancreatic cancer: Gemcitabine plus oncolytic measles vaccine virus.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2019 Nov ;18(5):5534-5542. Epub 2019 Sep 20. PMID: 31612061
Article Published Date : Oct 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Viruses: Beneficial
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemovirotherapy
[+]

Downregulation of lncRNA AFAP1-AS1 by oridonin inhibits the epithelial-to-mesenchymal transition and proliferation of pancreatic cancer cells.Aug 04, 2019

Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2019 Aug 5 ;51(8):814-825. PMID: 31314060
Article Published Date : Aug 04, 2019
Study Type : In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Ketogenic diet sensitizes murine pancreatic cancer tumors to cytotoxic chemotherapy.Feb 10, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med (N Y). 2022 Feb 11 ;3(2):119-136. PMID: 35425930
Article Published Date : Feb 10, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Pancreatic Cancer
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Antiproliferative , Chemosensitizer
[+]

Oridonin-loaded and GPC1-targeted gold nanoparticles for multimodal imaging and therapy in pancreatic cancer.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2018 ;13:6809-6827. Epub 2018 Oct 24. PMID: 30425490
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Gold (nanoparticles), Oridonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Cell cycle arrest
[+]

Overview of the anticancer activity of withaferin A, an active constituent of the Indian ginseng Withania somnifera.Jun 30, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Jul ;27(21):26025-26035. Epub 2020 May 13. PMID: 32405942
Article Published Date : Jun 30, 2020
Study Type : Review
Additional Links
Substances : Ashwagandha
Diseases : Breast Cancer, Colon Cancer, Lymphoma: B-Cell, Melanoma, Pancreatic Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts
[+]

Zyflamend induces apoptosis in pancreatic cancer cells via modulation of the JNK pathway,Aug 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Commun Signal. 2020 Aug 14 ;18(1):126. Epub 2020 Aug 14. PMID: 32795297
Article Published Date : Aug 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : Zyflamend
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Dose Response
[+]

"Genistein inhibits cell growth and induces apoptosis through up-regulation of miR-34a in pancreatic cancer cells."Nov 05, 2012

Pubmed Data : Curr Drug Targets. 2012 Nov 6. Epub 2012 Nov 6. PMID: 23140286
Article Published Date : Nov 05, 2012
Study Type : In Vitro Study
Additional Links
Substances : Genistein
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

"Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents."Jun 30, 2012

Pubmed Data : Gastroenterology. 2012 Jul ;143(1):234-45.e7. Epub 2012 Apr 14. PMID: 22510202
Article Published Date : Jun 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Cancer Stem Cells, Pancreatic Cancer, Pancreatic Stem Cell
Pharmacological Actions : Antineoplastic Agents, Proteasome Inhibitors
[+]

"Inhibitory effects of (-)-epigallocatechin-3-gallate and pterostilbene on pancreatic cancer growth in vitro."Sep 30, 2012

Pubmed Data : J Surg Res. 2012 Oct ;177(2):255-62. Epub 2012 May 3. PMID: 22583593
Article Published Date : Sep 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Pancreatic Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Cell cycle arrest
[+]

"Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90."Nov 30, 2012

Pubmed Data : J Nutr Biochem. 2012 Dec ;23(12):1617-26. Epub 2012 Mar 23. PMID: 22444872
Article Published Date : Nov 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Pancreatic Cancer
[+]

"Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells."Jan 01, 2011

Pubmed Data : Front Biosci (Elite Ed). 2011 ;3:515-28. Epub 2011 Jan 1. PMID: 21196331
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Quercetin, Sulforaphane
Diseases : Cancer Stem Cells, Pancreatic Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation
Additional Keywords : Cancer Stem Cells, Drug Synergy
[+]

(-)-Epigallocatechin 3-gallate inhibits pancreatic cancer cell growth. Dec 31, 2012

Pubmed Data : Int J Oncol. 2013 Jan ;42(1):349-58. Epub 2012 Nov 6. PMID: 23135610
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Pancreatic Cancer
[+]

A broad spectrum extract of turmeric (Turmeric Force) potentiates the anticancer activity of gemcitabine in pancreatic cancer cell lines.Jun 01, 2010

Pubmed Data : Oncol Rep. 2010 Jun;23(6):1529-35. PMID: 20428806
Article Published Date : Jun 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : NF-kappaB Inhibitor
Additional Keywords : Drug: Gemcitabine, Drug-Plant-Vitamin Synergies, New Chapter
[+]

A combination of benzyl isothiocyanate and sulforaphane have potent inhibitory activity in pancreatic cancer cells.Dec 01, 2002

Pubmed Data : Int J Cardiol. 2002 Dec;86(2-3):317-23. PMID: 19712481
Article Published Date : Dec 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Sulforaphane
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Natural Substance Synergy
[+]

A combination of lysine, proline, arginine, ascorbic acid and green tea extract inhibits a pancreatic cancer cell line. Jan 01, 2005

Pubmed Data : Int J Gastrointest Cancer. 2005;35(2):97-102. PMID: 15879623
Article Published Date : Jan 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Arginine, Green Tea, Lysine, Proline, Vitamin C
Diseases : Pancreatic Cancer
[+]

A combination of phenethyl isothiocyanate and TH588 has potential as a novel therapeutic strategy against pancreatic cancer.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Mar ;15(3):3240-3244. Epub 2017 Dec 29. PMID: 29435064
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Chemotherapeutic
[+]

A compound found within Prunus mume (Japanese apricot) inhibits the growth of pancreatic cancer cells. Mar 07, 2008

Pubmed Data : World J Gastroenterol. 2008 Mar 7;14(9):1378-82. PMID: 18322951
Article Published Date : Mar 07, 2008
Study Type : In Vitro Study
Additional Links
Substances : Ume (Japanese apricot)
Diseases : Pancreatic Cancer
[+]

A low-insulin response diet such as the macrobiotic diet may reduce pancreatic cancer morality. Aug 01, 2001

Pubmed Data : Med Hypotheses. 2001 Aug;57(2):146-50. PMID: 11461162
Article Published Date : Aug 01, 2001
Study Type : Commentary
Additional Links
Diseases : Pancreatic Cancer
Therapeutic Actions : Dietary Modification: Macrobiotic Diet
Additional Keywords : Insulin Associated Diseases
[+]

A review of the biological and therapeutic activities, and anticancer properties of curcumin.Oct 31, 2015

Pubmed Data : Exp Ther Med. 2015 Nov ;10(5):1615-1623. Epub 2015 Sep 17. PMID: 26640527
Article Published Date : Oct 31, 2015
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Arthritis, Head and Neck Cancer, Liver Cancer, Lung Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Skin Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antimutagenic Agents, Apoptotic, Cell cycle arrest
[+]

A review of the modulation of diverse oncogenic transcription factors by thymoquinone in cancers.Nov 20, 2017

Pubmed Data : Pharmacol Res. 2017 Nov 21. Epub 2017 Nov 21. PMID: 29162539
Article Published Date : Nov 20, 2017
Study Type : Review
Additional Links
Substances : Thymoquinone
Diseases : Breast Cancer, Colon Cancer, Lung Cancer, Pancreatic Cancer, Prostate Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

A study on the role of Taxifolin in inducing apoptosis of pancreatic cancer cells.Jan 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2024 Feb 1 ;16(3):2617-2637. Epub 2024 Feb 1. PMID: 38305809
Article Published Date : Jan 31, 2024
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
[+]

A water extract of olea europaea, corregiola variety had the highest cytotoxicity of the leaf extracts against the MiaPaCa-2 pancreatic cancer cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2015 ;20(7):12992-3004. Epub 2015 Jul 17. PMID: 26193251
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Olive leaf extract
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts
[+]

Acetyl-11-keto-β-boswellic acid suppresses invasion of pancreatic cancer cells.Jun 30, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Cancer. 2011 Jul 1 ;129(1):23-33. Epub 2011 Mar 29. PMID: 21448932
Article Published Date : Jun 30, 2011
Study Type : In Vitro Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic
[+]

Active ingredients of Inula helenium L. exhibits similar anti-cancer effects as isoalantolactone in pancreatic cancer cells.Aug 31, 2020

Pubmed Data : Nat Prod Res. 2020 Sep ;34(17):2539-2544. Epub 2019 Jan 19. PMID: 30661396
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Elecampane
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Natural Substances Versus Drugs, Plant Extracts
[+]

Acute/chronic exposure to bisphenol A induced immunotoxicity in zebrafish and its potential association with pancreatic cancer risk.Apr 30, 2023

Pubmed Data : Aquat Toxicol. 2023 May ;258:106514. Epub 2023 Mar 31. PMID: 37019016
Article Published Date : Apr 30, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Oxidative Stress, Pancreatic Cancer
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Immunotoxic
[+]

Advances in research on the relationship between thymoquinone and pancreatic cancer.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2022 ;12:1092020. Epub 2023 Jan 4. PMID: 36686732
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Thymoquinone
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Cell cycle arrest, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

After exposure to different oridonin concentrations, growth rates and cell cycle arrest of BxPC-3 cells were significantly reduced compared with untreated cells.Feb 28, 2015

Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2015 Mar ;47(3):164-73. Epub 2015 Feb 3. PMID: 25651847
Article Published Date : Feb 28, 2015
Study Type : In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-7 Activation , Cell cycle arrest
[+]

Agrimoniin sensitizes pancreatic cancer to apoptosis through ROS-mediated energy metabolism dysfunction.Jan 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2022 Feb ;96:153807. Epub 2021 Oct 19. PMID: 34785107
Article Published Date : Jan 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Agrimony, Polyphenols
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells.Dec 31, 2017

Pubmed Data : Toxicol Appl Pharmacol. 2018 10 1 ;356:159-171. Epub 2018 Aug 4. PMID: 30086361
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Elecampane
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Oxaliplatin
[+]

Alantolactone sensitizes human pancreatic cancer cells to EGFR inhibitors through the inhibition of STAT3 signaling.Dec 31, 2018

Pubmed Data : Mol Carcinog. 2019 04 ;58(4):565-576. Epub 2019 Jan 4. PMID: 30520143
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Elecampane
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, STAT3 Inhibitor
[+]

Algerian propolis may be an effective agent in a combined treatment with doxorubicin for increased therapeutic efficacy against pancreatic cancer.Dec 31, 2017

Pubmed Data : Anticancer Agents Med Chem. 2018 ;18(3):375-387. PMID: 29318976
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Bee Propolis
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin
[+]

Aloe emodin inhibits cancer cell growth in human pancreatic carcinoma cells.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J BUON. 2019 Mar-Apr;24(2):746-753. PMID: 31128032
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Emodin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Aloe polysaccharide induces autophagy in pancreatic carcinoma BxPC-3 cells both alone and in concert with radiation.Jun 30, 2016

Pubmed Data : Pak J Pharm Sci. 2016 Jul ;29(4):1123-6. PMID: 27393447
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Aloe Vera
Diseases : Pancreatic Cancer
Pharmacological Actions : Autophagy Up-regulation, MicroRNA modulator, Radiosensitizer
Additional Keywords : Polysaccharides
[+]

Andrographolide induces protective autophagy and targeting DJ-1 triggers reactive oxygen species-induced cell death in pancreatic cancer.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PeerJ. 2024 ;12:e17619. Epub 2024 Jun 28. PMID: 38952980
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Andrographolide
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
[+]

Andrographolide suppresses the malignancy of pancreatic cancer.Jul 03, 2024

Pubmed Data : Phytomedicine. 2024 Jul 4 ;132:155860. Epub 2024 Jul 4. PMID: 38991252
Article Published Date : Jul 03, 2024
Study Type : In Vitro Study
Additional Links
Substances : Andrographolide
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]

Anti-cancer properties of boswellic acids: mechanism of action as anti-cancerous agent.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2023 ;14:1187181. Epub 2023 Aug 3. PMID: 37601048
Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Substances : Frankincense
Diseases : Breast Cancer, Colon Cancer, Colorectal Cancer, Fibrosarcoma, Melanoma, Pancreatic Cancer, Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Anti-tumor and anti-metastasis effects of berbamine-loaded lipid nanoparticles on pancreatic cancer.Apr 30, 2022

Pubmed Data : Anticancer Agents Med Chem. 2022 May 1. Epub 2022 May 1. PMID: 35490430
Article Published Date : Apr 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Berbamine
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2019 Mar ;33(3):845-855. Epub 2019 Jan 10. PMID: 30632211
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Arugula, Isothiocyanates
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Antioxidant activity of banana flesh and antiproliferative effect on breast and pancreatic cancer cells.Feb 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2022 Mar ;10(3):740-750. Epub 2022 Jan 26. PMID: 35311172
Article Published Date : Feb 28, 2022
Study Type : In Vitro Study
Additional Links
Substances : Banana Peel
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Apigenin as tumor suppressor in cancers: biotherapeutic activity, nanodelivery, and mechanisms with emphasis on pancreatic cancer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Chem. 2020 ;8:829. Epub 2020 Oct 15. PMID: 33195038
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Cancers: All, Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Chemosensitizer, Hypoxia-inducible factor-1 (HIF-1) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Apigenin downregulates the tumor protein production (Geminin) contributing to its activity against pancreatic cancer cell lines. Nov 01, 2008

Pubmed Data : Mol Carcinog. 2008 Nov;47(11):835-44. PMID: 18404646
Article Published Date : Nov 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Pancreatic Cancer
[+]

Apigenin inhibits pancreatic cancer cell proliferation through cell cycle arrest. Feb 01, 2001

Pubmed Data : Diabetes Nutr Metab. 2001 Feb;14(1):37-42. PMID: 17196098
Article Published Date : Feb 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Pancreatic Cancer
[+]

Apigenin may inhibit pancreatic cancer through interfering with glucose uptake and transport. Nov 01, 2008

Pubmed Data : Pancreas. 2008 Nov;37(4):426-31. PMID: 18953257
Article Published Date : Nov 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents
[+]

Apigenin targets MicroRNA-155, enhances SHIP-1 expression, and augments anti-tumor responses in pancreatic cancer.Jul 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2022 Jul 25 ;14(15). Epub 2022 Jul 25. PMID: 35892872
Article Published Date : Jul 24, 2022
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Pancreatic Cancer
Pharmacological Actions : MicroRNA modulator
Additional Keywords : Tumor Microenvironment
[+]

Armed and targeted measles virus for chemovirotherapy of pancreatic cancer.Jul 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Gene Ther. 2011 Aug ;18(8):598-608. Epub 2011 Jun 24. PMID: 21701532
Article Published Date : Jul 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Viruses: Beneficial
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents
Additional Keywords : Chemovirotherapy
[+]

Artemisinin selectively induces apoptosis in pancreatic tumor cell line.Jul 31, 2014

Pubmed Data : Chin J Integr Med. 2014 Aug ;20(8):618-23. Epub 2013 Jun 15. PMID: 23771805
Article Published Date : Jul 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Selective Cytotoxicity
[+]

Attenuation of pancreatic cancer in vitro and in vivo.Jan 15, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2021 12 16 ;10(12). Epub 2021 Dec 16. PMID: 34944062
Article Published Date : Jan 15, 2021
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Phenethyl isothiocyanate, Xanthohumol
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
[+]

Autophagy is involved in Ficus carica fruit extract-induced anti-tumor effects on pancreatic cancer.May 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Jun ;150:112966. Epub 2022 Apr 12. PMID: 35427822
Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Baicalein flavone targets cisplatin resistant human pancreatic cancer cells.Jun 30, 2020

Pubmed Data : J BUON. 2020 Jul-Aug;25(4):1947-1953. PMID: 33099937
Article Published Date : Jun 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Baicalein
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Baicalein induces apoptosis of pancreatic cancer cells. Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2021 ;11:653061. Epub 2021 Apr 30. PMID: 33996574
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Baicalein
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, MicroRNA modulator
[+]

Baltic brown seaweed Fucus vesiculosus has strong anti-cancer activity as shown here under in vitro conditions.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2015 Jul ;13(7):4470-91. Epub 2015 Jul 20. PMID: 26204945
Article Published Date : Jun 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Seaweed: Brown
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Bee propolis is cytotoxic against a human pancreatic cancer cell line. Jul 02, 2009

Pubmed Data : J Nat Prod.2009 Jul 2. PMID: 19572611
Article Published Date : Jul 02, 2009
Study Type : In Vitro Study
Additional Links
Substances : Bee Propolis
Diseases : Pancreatic Cancer
[+]

Berbamine enhances the efficacy of gefitinib by suppressing STAT3 signalling in pancreatic cancer cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2019 ;12:11437-11451. Epub 2019 Dec 24. PMID: 31920333
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Berbamine
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer, STAT3 Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Gefitinib
[+]

Berbamine may be a promising candidate to be used in combination with gemcitabine for pancreatic cancer treatment.Apr 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Rec (Hoboken). 2014 May ;297(5):802-9. Epub 2014 Mar 12. PMID: 24619961
Article Published Date : Apr 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Berbamine
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Cyclin D1 Down-Regulation, P21 Activation
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Berberine exhibits preferential selectivity toward pancreatic cancer cells compared to normal ones.May 07, 2010

Pubmed Data : Planta Med. 2010 May 7. Epub 2010 May 7. PMID: 20455200
Article Published Date : May 07, 2010
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Pancreatic Cancer
Additional Keywords : Selective Cytotoxicity
[+]

Berberine overcomes gemcitabine-associated chemoresistance in pancreatic ductal adenocarcinoma.Sep 27, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2022 Sep 28 ;15(10). Epub 2022 Sep 28. PMID: 36297310
Article Published Date : Sep 27, 2022
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Berries are a plausible and potentially useful dietary strategy to reduce risk of cancer and help cancer patients with disease prognosis.Oct 18, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2016 Oct 19 ;5(4). Epub 2016 Aug 19. PMID: 27775562
Article Published Date : Oct 18, 2016
Study Type : Review
Additional Links
Substances : Berries: All
Diseases : Breast Cancer, Colon Cancer, Gastric Cancer, Lung Cancer, Pancreatic Cancer, Prostate Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

Betulinic acid acts as a chemosensitizer of gemcitabine.Jun 11, 2023

Pubmed Data : J Ethnopharmacol. 2023 Jun 12 ;309:116295. Epub 2023 Feb 21. PMID: 36813244
Article Published Date : Jun 11, 2023
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Betulinic acid inhibits stemness and EMT of pancreatic cancer cells via activation of AMPK signalingDec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2019 Jan ;54(1):98-110. Epub 2018 Oct 24. PMID: 30365057
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Chemosensitizer
Additional Keywords : Cancer Stem Cells, Chemotherapeutic Synergy: Gemcitabine
[+]

Biochanin A is effective in reducing pancreatic cancer cell survival by inhibiting their proliferation and inducing apoptosis.Feb 28, 2014

Pubmed Data : Anticancer Drugs. 2014 Mar ;25(3):296-302. PMID: 24201306
Article Published Date : Feb 28, 2014
Study Type : In Vitro Study
Additional Links
Substances : Biochanin A
Diseases : Cancer Metastasis, Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Dose Response
[+]

Bisdemethoxycurcumin partially offsets the chemoresistance induced by gemcitabine and produces apoptosis in PANC-1 cells.Nov 09, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Nov 10. Epub 2016 Nov 10. PMID: 27845899
Article Published Date : Nov 09, 2016
Study Type : In Vitro Study
Additional Links
Substances : Bisdemethoxycurcumin
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Bitter apricot ethanolic extract induces apoptosis in pancreatic cancer cells.Feb 04, 2020

Pubmed Data : Mol Biol Rep. 2020 Feb 5. Epub 2020 Feb 5. PMID: 32026321
Article Published Date : Feb 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Apricot
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
[+]

Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2015 Apr ;46(4):1849-57. Epub 2015 Feb 9. PMID: 25672620
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Bitter Melon
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents
Additional Keywords : Plant Extracts
[+]

Blockage of STAT3 signalling pathway by morusin induces apoptosis and inhibits invasion in human pancreatic tumor cells.Feb 29, 2016

Pubmed Data : Pancreas. 2016 Mar ;45(3):409-19. PMID: 26646273
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Cancer Metastasis, Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, STAT3 Inhibitor
[+]

Brazillian red propolis destroys pancreatic cancer cells in vitro. Jan 01, 2008

Pubmed Data : Bioorg Med Chem. 2008 Jan 1;16(1):181-9. Epub 2007 Oct 5. PMID: 17950610
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Bee Propolis
Diseases : Pancreatic Cancer
[+]

Cannabidiol and oxygen-ozone combination induce cytotoxicity in human pancreatic ductal adenocarcinoma cell lines.Sep 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2020 Sep 27 ;12(10). Epub 2020 Sep 27. PMID: 32992648
Article Published Date : Sep 26, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Pancreatic Cancer
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Chemotherapeutic
[+]

Cannabigerol induces autophagic cell death by inhibiting EGFR-RAS pathways in human pancreatic ductal adenocarcinoma cell lines.Feb 06, 2024

Pubmed Data : Int J Mol Sci. 2024 Feb 7 ;25(4). Epub 2024 Feb 7. PMID: 38396679
Article Published Date : Feb 06, 2024
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
[+]

Cannabinoids could be used for the inhibition of tumor growth in a clinical setting.Jan 14, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Res. 2008 Jan 15 ;68(2):339-42. PMID: 18199524
Article Published Date : Jan 14, 2008
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Breast Cancer, Cancers: All, Glioblastoma Multiforme, Lung Cancer, Lymphoma, Pancreatic Cancer, Prostate Cancer, Skin Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Higher Dose Better Than Lower Dose
[+]

Cannabinoids induce apoptosis of pancreatic tumor cells. Jul 01, 2006

Pubmed Data : Cancer Res. 2006 Jul 1;66(13):6748-55. PMID: 16818650
Article Published Date : Jul 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Cannabis
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
[+]

Cannabinoids inhibited pancreatic cancer.Oct 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Oct 28 ;21(21). Epub 2020 Oct 28. PMID: 33126623
Article Published Date : Oct 27, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Pancreatic Cancer
Pharmacological Actions : Immunomodulatory
[+]

Cannabinoids may be an effective adjunct for the treatment of pancreatic cancer.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pancreat Cancer. 2019 ;5(1):1-7. Epub 2019 Jan 25. PMID: 30706048
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemotherapeutic
[+]

CAPE is an effective inhibitor of neutrophil elastase via direct interaction whereby it inhibits the migration and growth of PANC-1 cells.Mar 20, 2017

Pubmed Data : Oncol Rep. 2017 Mar 21. Epub 2017 Mar 21. PMID: 28339071
Article Published Date : Mar 20, 2017
Study Type : In Vitro Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Cardamonin promotes the apoptosis and chemotherapy sensitivity to gemcitabine of pancreatic cancer.Sep 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dose Response. 2021 Oct-Dec;19(4):15593258211042163. Epub 2021 Dec 21. PMID: 34987330
Article Published Date : Sep 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Cardamonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Carotenoids from red palm and green tea polyphenols exhibit chemopreventive effects on pancreatic cancer cell lines. Jan 01, 1998

Pubmed Data : Pancreas. 1998 Jan;16(1):13-8. PMID: 9436857
Article Published Date : Jan 01, 1998
Study Type : In Vitro Study
Additional Links
Substances : Palm Oil
Diseases : Pancreatic Cancer
[+]

Carrot and carotene and multiple health outcomes: an umbrella review of the evidence.Mar 29, 2023

Pubmed Data : J Sci Food Agric. 2023 Mar 30 ;103(5):2251-2261. Epub 2023 Jan 17. PMID: 36600678
Article Published Date : Mar 29, 2023
Study Type : Review
Additional Links
Substances : beta-Carotene, Carotenoids, Carrot
Diseases : Alzheimer's Disease, Breast Cancer, Cataract, Gastric Cancer, Head and Neck Cancer, Pancreatic Cancer, Prostate Cancer
Pharmacological Actions : Chemopreventive, Neuroprotective Agents
Additional Keywords : Risk Reduction
[+]

Catechin and inositol hexaphosphate (IP6) inhibit pancreatic cancer growth in vitro. Jul 01, 2007

Pubmed Data : J Surg Res. 2007 Jul;141(1):115-9. PMID: 17574044
Article Published Date : Jul 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Catechin , Inositol Hexaphosphate
Diseases : Pancreatic Cancer
[+]

Chemovirotherapy of pancreatic adenocarcinoma by combining oncolytic vaccinia virus GLV-1h68 with nab-paclitaxel plus gemcitabine.Sep 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Ther Oncolytics. 2017 Sep 15 ;6:10-21. Epub 2017 Apr 19. PMID: 28607950
Article Published Date : Sep 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Viruses: Beneficial
Diseases : Pancreatic Cancer
Pharmacological Actions : Immunomodulatory
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Gemcitabine, Chemovirotherapy
[+]

Chia seeds ( Salvia hispanica L.): A therapeutic weapon in metabolic disorders.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2023 Jan ;11(1):3-16. Epub 2022 Dec 15. PMID: 36655089
Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Substances : Chia
Diseases : Cancers: All, Cardiovascular Diseases, Colorectal Cancer, Liver Cancer, Metabolic Diseases, Pancreatic Cancer
Pharmacological Actions : Antihypertensive Agents, Chemopreventive, Hypoglycemic Agents
[+]

Chinese skullcap contains compounds which inhibit human hepatoma and pancreatic cancer cell lines in vitro. Oct 28, 1994

Pubmed Data : Cancer Lett. 1994 Oct 28;86(1):91-5. PMID: 7954360
Article Published Date : Oct 28, 1994
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Hepatoma, Pancreatic Cancer
[+]

Chlorogenic acid depresses cellular bioenergetics to suppress pancreatic carcinoma.Nov 29, 2020

Pubmed Data : Phytother Res. 2020 Nov 30. Epub 2020 Nov 30. PMID: 33258205
Article Published Date : Nov 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Chloroquine potentiates the anticancer effect of pterostilbene on pancreatic cancer.Nov 07, 2021

Pubmed Data : Molecules. 2021 Nov 8 ;26(21). Epub 2021 Nov 8. PMID: 34771150
Article Published Date : Nov 07, 2021
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

Chokeberry extract in combination with gemcitabine was more effective than gemcitabine alone.Sep 16, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Pathol. 2014 Sep 17. Epub 2014 Sep 17. PMID: 25232128
Article Published Date : Sep 16, 2014
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins, Chokeberry
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine, Natural Substance/Drug Synergy
[+]

Coix seed extract could augment the efficacy of gemcitabine therapy in pancreatic cancer cells.Oct 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Oct 23 ;20(21). Epub 2019 Oct 23. PMID: 31652737
Article Published Date : Oct 22, 2019
Study Type : In Vitro Study
Additional Links
Substances : Adlay
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

Coix seed oil regulates mitochondrial functional damage to induce apoptosis of human pancreatic cancer.Jun 30, 2022

Pubmed Data : Mol Biol Rep. 2022 Jul ;49(7):5897-5909. Epub 2022 May 11. PMID: 35543827
Article Published Date : Jun 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Adlay
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
[+]

Combination of xanthohumol and phenethyl isothiocyanate inhibits NF-κB and activates Nrf2 in pancreatic cancer cells.Feb 14, 2020

Pubmed Data : Toxicol In Vitro. 2020 Feb 15:104799. Epub 2020 Feb 15. PMID: 32070777
Article Published Date : Feb 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate, Xanthohumol
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nrf2 activation
Additional Keywords : Natural Substance Synergy
[+]

Complications of percutaneous abdominal fine-needle biopsy. Review.Dec 31, 1990

Pubmed Data : Radiology. 1991 Jan ;178(1):253-8. PMID: 1984314
Article Published Date : Dec 31, 1990
Study Type : Review
Additional Links
Diseases : Liver Cancer, Pancreatic Cancer
Anti Therapeutic Actions : Fine Needle Aspiration
[+]

Constituents of propolis from Vietnamese Trigona minor have cytotoxicity activity against PANC-1 pancreatic cancer cells.Aug 06, 2017

Pubmed Data : J Nat Prod. 2017 Aug 7. Epub 2017 Aug 7. PMID: 28783356
Article Published Date : Aug 06, 2017
Study Type : In Vitro Study
Additional Links
Substances : Bee Propolis
Diseases : Pancreatic Cancer
Pharmacological Actions : Cytotoxic
[+]

Corn silk crude polysaccharide exerts anti-pancreatic cancer activity by blocking the EGFR/PI3K/AKT/CREB signaling pathway.Jul 31, 2020

Pubmed Data : Food Funct. 2020 Aug 1 ;11(8):6961-6970. Epub 2020 Jul 22. PMID: 32696775
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Corn Silk
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Polysaccharides
[+]

Crocetin, a compound found within saffron, inhibits the proliferation and tumor progression of pancreatic cancer in a xenograft mouse model. Feb 01, 2009

Pubmed Data : Mol Cancer Ther. 2009 Feb;8(2):315-23. Epub 2009 Feb 10. PMID: 19208826
Article Published Date : Feb 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Saffron
Diseases : Pancreatic Cancer
[+]

Crocin has therapeutic and preventive effects on cancer cell lines.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2020 Jan ;23(1):3-12. PMID: 32405344
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Crocin
Diseases : Breast Cancer, Colorectal Cancer, Leukemia: Chronic myelogenous leukemia (CML) , Pancreatic Cancer, Prostate Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest, Cyclin D1 Down-Regulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Telomerase Inhibitor
[+]

Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS‑activated pancreatic cancer cells.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2022 Sep ;61(3). Epub 2022 Jul 27. PMID: 35894141
Article Published Date : Aug 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Glutamine
Diseases : Colorectal Cancer, Pancreatic Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

Cucurbitacin B and SCH772984 exhibit synergistic anti-pancreatic cancer activitiesNov 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Nov 28 ;8(61):103167-103181. Epub 2017 Oct 9. PMID: 29262554
Article Published Date : Nov 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Survivin Down-Regulation
[+]

Cucurbitacin D is a promising candidate that should be explored further for its effectiveness as an anticancer agent against pancreatic cancer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:6571674. Epub 2020 Sep 22. PMID: 33029168
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin D
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Curcumin and L49H37 inhibit pancreatic stellate cells proliferation and induce apoptosis through downregulation of p21 and cell cycle arrest at the G0/G1 phase.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Gastroenterol. 2015 Jul-Sep;28(3):389-396. PMID: 26130500
Article Published Date : Jun 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Curcumin and soy isoflavones may work synergistically to prevent and treat pancreatic cancer.Aug 15, 2008

Pubmed Data : Life Sci. 2008 Aug 15;83(7-8):293-300. Epub 2008 Jun 28. PMID: 18640131
Article Published Date : Aug 15, 2008
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Isoflavones
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Curcumin augments gemcitabine cytotoxic effect on pancreatic cancer cell lines.Sep 01, 2007

Pubmed Data : Cancer Invest. 2007 Sep;25(6):411-8. PMID: 17882652
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer, Cyclooxygenase 2 Inhibitors
Additional Keywords : Drug: Gemcitabine, Drug Synergy
[+]

Curcumin causes cell cycle arrest and programmed cell death in human pancreatic cancer cells. May 05, 2009

Pubmed Data : Br J Cancer. 2009 May 5;100(9):1425-33. PMID: 19401701
Article Published Date : May 05, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
[+]

Curcumin could be candidate drug for targeting pancreatic cancer stem cells.Dec 27, 2015

Pubmed Data : Cell Cycle. 2015 Dec 28:0. Epub 2015 Dec 28. PMID: 26709750
Article Published Date : Dec 27, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Cancer Stem Cells
[+]

Curcumin could induce apoptosis in pancreatic cancer cells.Sep 30, 2015

Pubmed Data : Mol Med Rep. 2015 Oct ;12(4):5415-22. Epub 2015 Jul 8. PMID: 26166196
Article Published Date : Sep 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Bax/Bcl2 Ratio: Decrease, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest
[+]

Curcumin has anti-pancreatic and lung cancer activity.Nov 01, 2006

Pubmed Data : Anticancer Res. 2006 Nov-Dec;26(6B):4423-30. PMID: 17201164
Article Published Date : Nov 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Lung Cancer, Pancreatic Cancer
Pharmacological Actions : Apoptotic, Cyclooxygenase 2 Inhibitors, Epidermal growth factor receptor (EGFR) inhibitor
[+]

Curcumin inhibited cell proliferation and triggered cell cycle arrest and apoptosis in pancreatic cancer.May 19, 2017

Pubmed Data : Biochem Pharmacol. 2017 May 20. Epub 2017 May 20. PMID: 28535906
Article Published Date : May 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Curcumin inhibits cell growth and invasion through up-regulation of miR-7 in pancreatic cancer cells.Nov 17, 2014

Pubmed Data : Toxicol Lett. 2014 Nov 18 ;231(1):82-91. Epub 2014 Sep 23. PMID: 25256401
Article Published Date : Nov 17, 2014
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cancer Metastasis, Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, MicroRNA modulator
[+]

Curcumin inhibits human pancreatic cancer cell growth. Sep 15, 2002

Pubmed Data : Cancer. 2002 Sep 15;95(6):1206-14. PMID: 12216086
Article Published Date : Sep 15, 2002
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Interleukin-8 downregulation
[+]

Curcumin inhibits human pancreatic cancer cell growth. Nov 15, 2004

Pubmed Data : Cancer. 2004 Nov 15;101(10):2351-62. PMID: 15476283
Article Published Date : Nov 15, 2004
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Interleukin-8 downregulation, NF-kappaB Inhibitor, Prostaglandin PGE2 downregulation

Copyright: rob3000 / 123RF Stock Photo

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