Parkinsonian Disorders

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10 Substances Researched for Parkinsonian Disorders

Name	AC	CK
Ginkgo biloba	1	3
Multivitamin	1	3
Coenzyme Q10	1	2
Dopa bean	1	2
Nobiletin	1	2
Pantothenic Acid (Vitamin B-5)	1	2
18β-Glycyrrhetinic Acid	1	1
Fucoidan	1	1
Mulberry	1	1
Resveratrol	1	1

3 Problem Substances Researched for Parkinsonian Disorders

Name	AC	CK
Glyphosate	4	8
Gluten	1	3
Wheat	1	3

1 Therapeutic Actions Researched for Parkinsonian Disorders

Name	AC	CK	Focus
Dietary Modification: Wheat/Gluten Free	1	3

1 Problematic Actions Researched for Parkinsonian Disorders

Name	AC	CK	Focus
Vaccination: Measles	1	3

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

View the Evidence:
14 Abstracts with Parkinsonian Disorders Research

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[+]

Dramatic improvement of parkinsonian symptoms after gluten-free diet introduction in a patient with silent celiac disease.Jan 31, 2014

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Pubmed Data : J Neurol. 2014 Feb ;261(2):443-5. Epub 2014 Jan 25. PMID: 24464413

Article Published Date : Jan 31, 2014

Study Type : Human: Case Report

Additional Links

Diseases : Idiopathic Parkinson Disease, Parkinson's, Parkinsonian Disorders, Parkinsonism

Therapeutic Actions : Dietary Modification: Wheat/Gluten Free

Problem Substances : Gluten, Wheat

[+]

Ginkgo biloba and/or a multivitamin-multimineral supplement effected remarkable improvement in symptoms in this case report. Jun 30, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Glob Adv Health Med. 2014 Jul ;3(4):43-4. PMID: 25105077

Article Published Date : Jun 30, 2014

Study Type : Human: Case Report

Additional Links

Substances : Ginkgo biloba, Multivitamin

Diseases : Parkinson's Disease, Parkinsonian Disorders

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Significant Treatment Outcome

[+]

Glyphosate-induced parkinsonism has been reported. May 01, 2001

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Pubmed Data : Mov Disord. 2001 May ;16(3):565-8. PMID: 11391760

Article Published Date : May 01, 2001

Study Type : Human: Case Report

Additional Links

Diseases : Dopamine Levels: Low, Glyphosate Toxicity, Neurotoxicity, Parkinsonian Disorders, Substantia Nigra: Damage

Problem Substances : Glyphosate

Adverse Pharmacological Actions : Neurotoxic

[+]

Measles vaccine and glyphosate-induced parkinsonism has been reported. Jun 01, 2003

Click here to read the entire abstract

Pubmed Data : Arq Neuropsiquiatr. 2003 Jun ;61(2B):381-6. Epub 2003 Jul 28. PMID: 12894271

Article Published Date : Jun 01, 2003

Study Type : Human: Case Report

Additional Links

Diseases : Glyphosate Toxicity, Parkinsonian Disorders, Vaccine-induced Toxicity

Anti Therapeutic Actions : Vaccination: Measles

Problem Substances : Glyphosate

Adverse Pharmacological Actions : Neurotoxic

[+]

A water extract of Mucuna pruriens provides long-term amelioration of parkinsonism with reduced risk for dyskinesias.Aug 01, 2010

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Pubmed Data : Parkinsonism Relat Disord. 2010 Aug;16(7):458-65. Epub 2010 May 31. PMID: 20570206

Article Published Date : Aug 01, 2010

Study Type : Animal Study

Additional Links

Substances : Dopa bean

Diseases : Dyskinesia Syndromes, Parkinson's Disease, Parkinsonian Disorders

[+]

Coenzyme Q10 prevents paraquat-induced oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats.Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : BMC Neurosci. 2009;10:88. Epub 2009 Jul 27. PMID: 19635141

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Coenzyme Q10

Diseases : Oxidative Stress, Parkinson's Disease, Parkinsonian Disorders

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Deltamethrin intranasal administration induces memory, emotional and tyrosine hydroxylase immunoreactivity alterations in rats.Aug 31, 2018

Click here to read the entire abstract

Pubmed Data : Brain Res Bull. 2018 Sep ;142:297-303. Epub 2018 Aug 15. PMID: 30118749

Article Published Date : Aug 31, 2018

Study Type : Animal Study

Additional Links

Diseases : Parkinsonian Disorders, Pesticide Toxicity

Problem Substances : Deltamethrin, Pesticides

Adverse Pharmacological Actions : Neurotoxic

[+]

Nobiletin rescues motor and cognitive dysfunction in a MPTP-induced Parkinson model mice, in part by enhancing dopamine release.Feb 13, 2014

Click here to read the entire abstract

Pubmed Data : Neuroscience. 2014 Feb 14 ;259:126-41. Epub 2013 Dec 4. PMID: 24316474

Article Published Date : Feb 13, 2014

Study Type : Animal Study

Additional Links

Substances : Nobiletin

Diseases : Cognitive Decline/Dysfunction, Parkinson's Disease, Parkinsonian Disorders

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Additional Keywords : Significant Treatment Outcome

[+]

Pantothenic acid may have a therapeutic and restorative role in the movement disorder known as Hallervorden-Spatzy syndrome. Jun 01, 2007

Click here to read the entire abstract

Pubmed Data : J Inherit Metab Dis. 2007 Jun;30(3):310-7. Epub 2007 Apr 12. PMID: 17429753

Article Published Date : Jun 01, 2007

Study Type : Animal Study

Additional Links

Substances : Pantothenic Acid (Vitamin B-5)

Diseases : Hallervorden-Spatz Syndrome, Parkinsonian Disorders

[+]

A form of reseveratrol from Mulbery protects against parkinsonian mimetic 6-hydroxydopamine.Oct 01, 2008

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Pubmed Data : Free Radic Biol Med. 2008 Oct 1;45(7):1019-26. Epub 2008 Jul 16. PMID: 18675900

Article Published Date : Oct 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Mulberry, Resveratrol

Diseases : Neurodegenerative Diseases, Parkinson's Disease, Parkinsonian Disorders

Pharmacological Actions : Neuroprotective Agents

[+]

Exposure to glyphosate- and/or Mn/Zn-ethylene-bis-dithiocarbamate-containing pesticides leads to degeneration ofγ-aminobutyric acid and dopamine neurons in Caenorhabditis elegans.Apr 01, 2012

Click here to read the entire abstract

Pubmed Data : Neurotox Res. 2012 Apr ;21(3):281-90. Epub 2011 Sep 16. PMID: 21922334

Article Published Date : Apr 01, 2012

Study Type : In Vitro Study

Additional Links

Diseases : Dopamine Levels: Low, Glyphosate Toxicity, Neurodegenerative Diseases, Neurotoxicity, Parkinson's Disease, Parkinsonian Disorders, Substantia Nigra: Damage

Problem Substances : Glyphosate

Adverse Pharmacological Actions : Neurotoxic

[+]

Fucoidan protects against lipopolysaccharide-induced rat neuronal damage and inhibits the production of proinflammatory mediators in primary microglia.Sep 30, 2012

Click here to read the entire abstract

Pubmed Data : CNS Neurosci Ther. 2012 Oct ;18(10):827-33. PMID: 23006515

Article Published Date : Sep 30, 2012

Study Type : In Vitro Study

Additional Links

Substances : Fucoidan

Diseases : Brain: Microglial Activation, Lipopolysaccharide-Induced Toxicity, Parkinsonian Disorders

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Glycyrrhetinic acid and E.resveratroloside are potent compounds having high binding energies which should be considered as potential lead compounds for drug development against PD.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Drug Des Devel Ther. 2015 ;9:187-98. Epub 2014 Dec 18. PMID: 25565772

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : 18β-Glycyrrhetinic Acid

Diseases : Neurodegenerative Diseases, Parkinson's Disease, Parkinsonian Disorders

Pharmacological Actions : Dopamine Antagonists, Dopamine Receptor D3 Antagonist, Neuroprotective Agents

[+]

Glyphosate induces cell death through apoptotic and autophagic mechanisms, indicating a mechanism behind the association between glyphosate exposure and Parkinsonism. Apr 04, 2012

Click here to read the entire abstract

Pubmed Data : Neurotoxicol Teratol. 2012 Apr 4. Epub 2012 Apr 4. PMID: 22504123

Article Published Date : Apr 04, 2012

Study Type : In Vitro Study

Additional Links

Diseases : Parkinson's Disease, Parkinsonian Disorders

Problem Substances : Glyphosate

Adverse Pharmacological Actions : Neurotoxic

Parkinsonian Disorders Related Articles

Dramatic Recovery In Parkinson’s Patient with Gluten Free Diet

Written by Sayer Ji, Founder

Could gluten's toxicity extend to the nervous system, producing symptoms identical to classical Parkinson's disease? A compelling case study adds to a growing body of research indicating that wheat's neurotoxicity is greatly underestimated.

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 14 Abstracts with Parkinsonian Disorders Research

Limited to Members Only

Currently Available Sorting Options

Dramatic improvement of parkinsonian symptoms after gluten-free diet introduction in a patient with silent celiac disease.Jan 31, 2014

Ginkgo biloba and/or a multivitamin-multimineral supplement effected remarkable improvement in symptoms in this case report. Jun 30, 2014

Glyphosate-induced parkinsonism has been reported. May 01, 2001

Measles vaccine and glyphosate-induced parkinsonism has been reported. Jun 01, 2003

A water extract of Mucuna pruriens provides long-term amelioration of parkinsonism with reduced risk for dyskinesias.Aug 01, 2010

Coenzyme Q10 prevents paraquat-induced oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats.Jan 01, 2009

Deltamethrin intranasal administration induces memory, emotional and tyrosine hydroxylase immunoreactivity alterations in rats.Aug 31, 2018

Nobiletin rescues motor and cognitive dysfunction in a MPTP-induced Parkinson model mice, in part by enhancing dopamine release.Feb 13, 2014

Pantothenic acid may have a therapeutic and restorative role in the movement disorder known as Hallervorden-Spatzy syndrome. Jun 01, 2007

A form of reseveratrol from Mulbery protects against parkinsonian mimetic 6-hydroxydopamine.Oct 01, 2008

Exposure to glyphosate- and/or Mn/Zn-ethylene-bis-dithiocarbamate-containing pesticides leads to degeneration ofγ-aminobutyric acid and dopamine neurons in Caenorhabditis elegans.Apr 01, 2012

Fucoidan protects against lipopolysaccharide-induced rat neuronal damage and inhibits the production of proinflammatory mediators in primary microglia.Sep 30, 2012

Glycyrrhetinic acid and E.resveratroloside are potent compounds having high binding energies which should be considered as potential lead compounds for drug development against PD.Dec 31, 2014

Glyphosate induces cell death through apoptotic and autophagic mechanisms, indicating a mechanism behind the association between glyphosate exposure and Parkinsonism. Apr 04, 2012

Parkinsonian Disorders Related Articles

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Parkinsonian Disorders

View the Evidence:
14 Abstracts with Parkinsonian Disorders Research