Parkinson's Disease

Name	AC	CK
Coenzyme Q10	12	61
Cannabidiol	14	51
Melatonin	10	40
Mucuna pruriens (aka Velvet Beans)	13	39
Curcumin	30	38
Ginsenosides	11	32
Bee Venom	8	30
Vitamin D	2	30
Flavonoids	15	29
Baicalein	6	28
Vitamin C	7	26
B-complex	3	22
Anthocyanins	3	21
Vitamin B-12	3	21
Polyphenols	14	19
Carvacrol	5	18
Palmitoylethanolamide	5	18
Probiotics	7	18
Resveratrol	14	18
Puerarin	9	17
Crocin	9	16
EGCG (Epigallocatechin gallate)	11	15
Ginkgo biloba	3	14
Vitamin B-6	4	14
Alpha-Lipoic Acid	3	13
Catechin	6	13
Fucoidan	8	13
Ginseng (Korean)	7	13
Thymoquinone	10	13
Cannabis	3	12
Naringenin	7	12
Cannabinoids	8	11
Chrysin	6	11
Delta-tetrahydrocannabinol (THC)	5	11
Safflower	6	11
Astaxanthin	9	10
Black Currant	1	10
Cholesterol	1	10
Coconut Oil	1	10
Culinary Herbs and Spices	1	10
Fisetin	6	10
Fish Oil	1	10
Fruit: All	1	10
Gastrodin	5	10
Grape	1	10
NAC (N-acetyl-L-cysteine)	1	10
Olive Oil	1	10
Prebiotics	1	10
Pycnogenol (Pine Bark)	1	10
SAMe (S-adenosylmethionine)	1	10
Vegetables: All	1	10
Vitamin B-3 (Niacin)	1	10
Quercetin	7	9
Black Tea	5	8
Piperine	5	8
Astragaloside	5	7
Green Tea	6	7
Gynostemma	4	7
Paeoniflorin	4	7
Peony	4	7
Phloretin	2	7
Asiatic Acid	4	6
Bacopa	4	6
Gotu Kola	5	6
Holy Basil	2	6
Nobiletin	4	6
Tea	4	6
Agaricus Blazei	3	5
Amurensin G	1	5
Ashwagandha	4	5
Beta-Caryophyllene	3	5
Citrus naringin	3	5
DHA (Docosahexaenoic Acid)	3	5
Demethoxycurcumin	3	5
Echinacea	3	5
Hesperidin	3	5
Honokiol	3	5
Hydroxytyrosol	3	5
Omega-3 Fatty Acids	4	5
Saffron	3	5
Tangeretin	3	5
Theaflavins	3	5
Vanillin	3	5
Walnut	3	5
6-Shogaol	3	4
Carnosic Acid	4	4
Chlorogenic Acid	3	4
Dopa bean	2	4
Ellagic Acid	2	4
Gold (nanoparticles)	2	4
Grape Seed Extract	2	4
Lion's Mane (Hericium Erinaceus)	3	4
Long Pepper	2	4
Mangosteen	3	4
Passion Flower	2	4
Seaweed: Brown	2	4
Sesamin	2	4
Spirulina	2	4
Sulforaphane	4	4
Toona sinensis	2	4
Ursolic Acid	2	4
Verbascoside	2	4
Ayahuasca	2	3
Blueberry	2	3
Caffeic acid phenethyl ester	2	3
Carotenoids	3	3
Chaenomeles speciosa	2	3
Chinese Skullcap	2	3
Daidzein	2	3
Folic Acid	2	3
Fucoxanthin	2	3
Genistein	2	3
Geraniol	2	3
Guduchi	2	3
Lactobacillus plantarum	2	3
Licorice	2	3
Lutein	2	3
Luteolin	2	3
Lycopene	3	3
Magnesium	2	3
Mangiferin	3	3
Melanin: Bacterial	2	3
Multivitamin	1	3
Myricetin	2	3
Nigella sativa (aka Black Seed)	3	3
Noni	2	3
Oleuropein	3	3
Piceatannol	2	3
Pistachio nut	2	3
Reishi Mushroom	2	3
Rosemary	3	3
Rutin	3	3
Spikenard	2	3
Stilbenes	2	3
Syrian rue	2	3
Tanshinone IIA	2	3
Vitamin E	2	3
Amla Fruit	2	2
Antrodia camphorata	1	2
Arctigenin	1	2
Beet	1	2
Berberine	1	2
Bifidobacterium Breve	1	2
Biochanin A	1	2
Black Tea Theaflavins	1	2
Blackberry	1	2
Brown Rice: Pre-Germinated	1	2
Butyrate	1	2
Carnosine	1	2
Cashew	1	2
Celastrol	1	2
Celery	1	2
Chia	2	2
Coffee	2	2
Cordyceps sinensis	1	2
Creatine	1	2
Crocetin	1	2
Diosgenin	1	2
Dogwood	1	2
Essential Oils: Unspecified	1	2
Ferulic acid	1	2
Frankincense	1	2
Garlic	1	2
Ginger	2	2
Gingerol	2	2
Glutathione	2	2
Hydrogen Water	1	2
Indole-3-Carbinol	1	2
Isoflavones	1	2
Isothiocyanate	1	2
Lupeol	1	2
Moringa oleifera	1	2
Nettle	1	2
Octacosanol	1	2
Olive leaf extract	1	2
Paeonol	2	2
Piperlongumine	1	2
Polyunsaturated Fatty Acids (PUFAs)	2	2
Pomegranate	1	2
Psyllium	1	2
Pumpkin Seeds	1	2
Purslane	1	2
Red Wine Extract	2	2
Rosmarinic acid	2	2
Safranal	1	2
Schisandra	1	2
Selenium	2	2
Sesamol	1	2
Silibinin	1	2
Silymarin	1	2
Soy Protein	1	2
St. Johns Wort	1	2
Tetrahydrocurcumin	1	2
Theanine	2	2
Thymol	1	2
Tocotrienol: Delta	1	2
Ubiquinol	1	2
Urolithin A	1	2
Vitexins	1	2
18β-Glycyrrhetinic Acid	1	1
Algae	1	1
Apigenin	1	1
Astragalus	1	1
Avocado	1	1
Bamboo	1	1
Basil	1	1
Bee Propolis	1	1
Betanin	1	1
Bisdemethoxycurcumin	1	1
Cannabinoids: Synthetic	1	1
Carnosol	1	1
Chrysanthemum Indicum	1	1
Cocoa	1	1
Cordyceps Militaris	1	1
Cucurbitacin E	1	1
Cumin	1	1
Cysteine (see N-Acetylcysteine)	1	1
EPA (Eicosapentaenoic Acid)	1	1
Elderberry	1	1
Essential Fatty Acids	1	1
Fenugreek	1	1
Fermented Foods and Beverages	1	1
Garlic: Aged	1	1
Genipin	1	1
Ginseng	1	1
Glycyrrhiza uralensis	1	1
Goji	1	1
Harmine	1	1
Honeysuckle	1	1
Isoliquiritigenin	1	1
Kimchi	1	1
Lactobacillus probiotics	1	1
Magnolol	1	1
Medicinal Mushrooms	1	1
Mulberry	1	1
Neem	1	1
Olive	1	1
Onion	1	1
Punicalagin	1	1
Red Sage	1	1
Riboflavin (Vitamin B-2)	1	1
Rose	1	1
Rosemaric Acid	1	1
Royal Jelly	1	1
Ruta Graveolens	1	1
Seaweed	1	1
Soursop	1	1
Tauroursodeoxycholic acid	1	1
Turmeric	1	1
Vitamin K2	1	1
Water: Deuterium Depleted	1	1
Wine	1	1
Xanthones	1	1
beta-Carotene	1	1

Name	AC	CK
Rotenone	19	34
Pesticides	5	25
Glyphosate	4	13
Bisphenol A	2	12
Antibiotics	2	11
Cholinesterase Inhibitor Drugs	2	11
Antipsychotic Drugs	1	10
Dental Amalgams	1	10
Mercury	1	10
Paraquat	3	7
Chlorpyrifos	2	3
Aluminum	2	2
Aluminum Chloride	1	2
Aspartame	1	2
Glyphosate formulations	1	2
Lead	1	2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	2
Roundup (herbicide)	1	2
Tamoxifen	1	2
Dimethoate	1	1
Donepezil (trade name Aricept)	1	1
Galantamine	1	1
Rivastigmine	1	1
Zineb	1	1

Name	AC	CK
Qigong	6	90
Tai Chi	7	90
Exercise	14	44
Acupuncture	5	33
Ai-Chi Aquatic Exercise	3	30
Exercise: Cycling	3	30
Electroacupuncture	7	22
Dancing	2	20
Sunlight exposure	1	20
Dietary Modification: Low Carbohydrate/Ketogenic	3	13
Music	3	12
Yoga	3	12
Exercise: Aerobic	2	11
Drumming	1	10
Guided Imagery	1	10
Massage/Therapeutic Touch	1	10
Relaxation Therapy	1	10
Laser Treatment: Low-Level	3	5
Melodic Intonation Therapy	2	2
Fasting/Caloric Restriction	1	1
Meditation	1	1
Microbiota Transfer Therapy	1	1
Mind-Body Therapies	1	1

Name	AC	CK
Vaccination: All	2	4
Electromagnetic Field Harms	1	1
Mobile Phone Radiation	1	1

[+]

Baicalein exerts potential neuroprotective effects through multiple signaling pathways in animal models of Parkinson's disease.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Aging Neurosci. 2020 ;12:277. Epub 2020 Sep 25. PMID: 33101006

Article Published Date : Dec 31, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : Baicalein

Diseases : Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Effect of ginsenoside-Rg1 on experimental Parkinson's disease.May 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2021 Jun ;21(6):552. Epub 2021 Mar 25. PMID: 33850524

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Pubmed Data : Clin Rehabil. 2020 Dec ;34(12):1436-1448. Epub 2020 Jul 29. PMID: 32727214

Article Published Date : Nov 30, 2020

Study Type : Meta Analysis, Review

Additional Links

Diseases : Parkinson's Disease

Therapeutic Actions : Qigong

Pharmacological Actions : Neuroprotective Agents

[+]

Reduced exposure to sunlight were significantly associated with an increased risk of Parkinson's disease.Jan 22, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Med Sci Monit. 2019 Jan 23 ;25:666-674. Epub 2019 Jan 23. PMID: 30672512

Article Published Date : Jan 22, 2019

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Pubmed Data : Neurol Sci. 2015 Aug 9. Epub 2015 Aug 9. PMID: 26255301

Article Published Date : Aug 08, 2015

Study Type : Meta Analysis

Additional Links

Substances : Melatonin

Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease

[+]

Vitamin E might have a protective effect against Parkinson's disease.May 20, 2021

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Pubmed Data : Clin Nutr. 2021 May 21 ;40(6):3922-3930. Epub 2021 May 21. PMID: 34139465

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 1995 Fall;1(3):249-55. PMID: 9395621

Article Published Date : Sep 01, 1995

Study Type : Human Study

Additional Links

Substances : Mucuna pruriens (aka Velvet Beans)

Diseases : Parkinson's Disease

[+]

A single bout of aerobic exercise improves motor skill consolidation in Parkinson's disease.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Aging Neurosci. 2018 ;10:328. Epub 2018 Oct 22. PMID: 30405397

[+]

Aquatic Ai Chi applied twice weekly may potentially reduce Parkinsonian symptoms.Jan 31, 2018

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Pubmed Data : Complement Ther Med. 2018 Feb ;36:147-153. Epub 2017 Dec 8. PMID: 29458923

Article Published Date : Jan 31, 2018

Study Type : Human Study

Additional Links

Diseases : Parkinson's Disease

Therapeutic Actions : Ai-Chi Aquatic Exercise

[+]

Ascorbate status was positively associated with cognitive function in Parkinson's disease.Sep 22, 2020

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Pubmed Data : Antioxidants (Basel). 2020 Sep 23 ;9(10). Epub 2020 Sep 23. PMID: 32977491

Article Published Date : Sep 22, 2020

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Parkinson's Disease, Vitamin C Deficiency

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Factors

[+]

Association between anticholinergic medication use and risk of dementia among patients with Parkinson's disease.Jun 27, 2019

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Pubmed Data : Pharmacotherapy. 2019 Jun 28. Epub 2019 Jun 28. PMID: 31251824

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Pubmed Data : Nutrients. 2018 Jun 2 ;10(6). Epub 2018 Jun 2. PMID: 29865234

Combined treatment with acupuncture and bee venom acupuncture showed promising results as a safe adjunctive therapy for PD.Sep 30, 2015

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Pubmed Data : J Altern Complement Med. 2015 Oct ;21(10):598-603. Epub 2015 Jul 31. PMID: 26230989

Article Published Date : Sep 30, 2015

Pubmed Data : Parkinsonism Relat Disord. 2016 Nov ;32:66-72. Epub 2016 Aug 26. PMID: 27591074

Article Published Date : Oct 31, 2016

Study Type : Human Study

Additional Links

Diseases : Dysbiosis, Parkinson's Disease

Additional Keywords : Microbiota, Risk Factors

[+]

Ginkgo biloba extract may attentuate the neurotoxic effects of levodopa in parkinson disease.Jan 01, 2003

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Pubmed Data : J Huazhong Univ Sci Technolog Med Sci. 2003;23(2):151-3. PMID: 12973934

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : Ginkgo biloba

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Glyphosate has shown to be associated with the odds of premature mortality from Parkinson's disease.Dec 15, 2018

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Pubmed Data : Int J Environ Res Public Health. 2018 Dec 16 ;15(12). Epub 2018 Dec 16. PMID: 30558363

Article Published Date : Dec 15, 2018

Study Type : Human Study

Additional Links

Diseases : Glyphosate Toxicity, Parkinson's Disease

Additional Keywords : Increased Risk, Mortality

Problem Substances : Glyphosate

[+]

Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progression.May 31, 2019

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Pubmed Data : PLoS One. 2011 ;6(8):e22854. Epub 2011 Aug 11. PMID: 21853051

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Substances : Cholesterol

Diseases : Parkinson's Disease

[+]

Click here to read the entire abstract

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Pubmed Data : PLoS One. 2016 ;11(12):e0166552. Epub 2016 Dec 1. PMID: 27906991

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Diseases : Parkinson's Disease

Additional Keywords : Risk Factors

Problem Substances : Dental Amalgams, Mercury

[+]

Qigong exercise decreased TNF-α level in people with Parkinson's disease and helped improve sleep quality.Apr 22, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicines (Basel). 2017 Apr 23 ;4(2). Epub 2017 Apr 23. PMID: 28930237

[+]

Sam-e appears to be well tolerated and effect in the treatment of depression in Parkinson's disease.Nov 01, 2000

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Pubmed Data : Mov Disord. 2000 Nov;15(6):1225-9. PMID: 11104210

Article Published Date : Nov 01, 2000

Study Type : Human Study

Additional Links

Substances : SAMe (S-adenosylmethionine)

Diseases : Parkinson's Disease

[+]

Separate or concurrent use of antiemetics and antipsychotics showed increased risks of Parkinson's disease.Dec 10, 2018

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Pubmed Data : Int J Clin Pharmacol Ther. 2018 Dec 11. Epub 2018 Dec 11. PMID: 30526811

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Pubmed Data : Gait Posture. 2008 Oct;28(3):456-60. Epub 2008 Apr 18. PMID: 18378456

Article Published Date : Oct 01, 2008

Study Type : Human Study

Additional Links

Diseases : Parkinson's Disease

Therapeutic Actions : Tai Chi

[+]

Tai Chi had the potential to slow down the progression of symptoms of Parkinson's disease and delayed the introduction of levodopa.Dec 31, 2019

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Pubmed Data : Braz J Med Biol Res. 2020 ;53(2):e9171. Epub 2020 Feb 10. PMID: 32049101

Article Published Date : Dec 31, 2019

Pubmed Data : Physiol Behav. 2020 Aug 14 ;227:113135. Epub 2020 Aug 14. PMID: 32798568

Article Published Date : Aug 13, 2020

Study Type : Human Study

Additional Links

Substances : Grape

Diseases : Parkinson's Disease

Therapeutic Actions : Exercise

Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents

Additional Keywords : Epigenetic Modification

[+]

The combination of carvacrol and exercise could be an effective therapeutic tool for treatment of neurobehavioral deficits in Parkinson's disease patients.Jul 28, 2019

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Pubmed Data : Arq Neuropsiquiatr. 2019 Jul 29 ;77(7):493-500. Epub 2019 Jul 29. PMID: 31365641

Click here to read the entire abstract

Pubmed Data : J Neural Transm. 2015 Sep 5. Epub 2015 Sep 5. PMID: 26343034

Article Published Date : Sep 04, 2015

Study Type : Human Study

Additional Links

Diseases : Endothelial Dysfunction, Parkinson's Disease, Vitamin D Deficiency

[+]

These findings suggest that the intake of some flavonoids may reduce Parkinson’s disease risk.Apr 09, 2012

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Pubmed Data : Neurology. 2012 Apr 10 ;78(15):1138-45. Epub 2012 Apr 4. PMID: 22491871

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Pubmed Data : Vet World. 2016 Dec ;9(12):1348-1354. Epub 2016 Dec 3. PMID: 28096604

Article Published Date : Nov 30, 2016

Study Type : Human In Vitro

Additional Links

Substances : Holy Basil

Diseases : Alzheimer's Disease, Dementia, Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Plant Extracts

[+]

Amurensin G induces autophagy and attenuates cellular toxicities in a rotenone model of Parkinson's disease.Mar 28, 2013

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Pubmed Data : Biochem Biophys Res Commun. 2013 Mar 29 ;433(1):121-6. Epub 2013 Feb 26. PMID: 23485458

Article Published Date : Mar 28, 2013

Study Type : Human In Vitro

Additional Links

Substances : Amurensin G

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Phytotherapy

Problem Substances : Rotenone

[+]

Neurorescue activity, APP regulation and amyloid-beta peptide reduction by novel multi-functional brain permeable iron- chelating- antioxidants, M-30 and green tea polyphenol, EGCG.Sep 01, 2007

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Pubmed Data : Curr Alzheimer Res. 2007 Sep ;4(4):403-11. PMID: 17908043

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Pubmed Data : Glob Adv Health Med. 2014 Jul ;3(4):43-4. PMID: 25105077

Article Published Date : Jun 30, 2014

Study Type : Human: Case Report

Additional Links

Substances : Ginkgo biloba, Multivitamin

Diseases : Parkinson's Disease, Parkinsonian Disorders

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Significant Treatment Outcome

[+]

Parkinson's disease due to laboral exposition to paraquatOct 31, 2012

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Pubmed Data : Rev Med Inst Mex Seguro Soc. 2012 Nov-Dec;50(6):665-72. PMID: 23331754

Article Published Date : Oct 31, 2012

Study Type : Human: Case Report

Additional Links

Diseases : Parkinson's Disease

Problem Substances : Paraquat

Adverse Pharmacological Actions : Neurotoxic

[+]

Three case studies of post-vaccinal parkinsonism.Nov 30, 2002

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Pubmed Data : Med Hypotheses. 2002 Dec ;59(6):762-9. PMID: 12445523

Article Published Date : Nov 30, 2002

Study Type : Human: Case Report

Additional Links

Diseases : Parkinson's Disease

Anti Therapeutic Actions : Vaccination: All

[+]

Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides.Jul 15, 2020

Pubmed Data : Int J Mol Sci. 2016 ;17(1). Epub 2016 Jan 15. PMID: 26784178

Article Published Date : Dec 31, 2015

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Pubmed Data : Food Chem Toxicol. 2018 Sep ;119:6-13. Epub 2018 Jun 12. PMID: 29906474

Article Published Date : Aug 31, 2018

Study Type : Animal Study

Additional Links

Substances : Verbascoside

Diseases : Parkinson's Disease

Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation

[+]

Acupuncture inhibits the increase in alpha-synuclein in substantia nigra in an MPTP-induced Parkinsonism.Dec 31, 2019

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Pubmed Data : Adv Exp Med Biol. 2020 ;1232:401-408. PMID: 31893437

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Pubmed Data : Planta Med. 2016 May 25. Epub 2016 May 25. PMID: 27224270

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Pubmed Data : Neurochem Int. 2018 Dec ;121:98-107. Epub 2018 Oct 5. PMID: 30296463

Beneficial effect of rice bran extract against rotenone-induced experimental Parkinson's disease.Jan 24, 2021

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Pubmed Data : Curr Mol Pharmacol. 2021 Jan 25. Epub 2021 Jan 25. PMID: 33573588

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Pubmed Data : Biol Trace Elem Res. 2022 Jan 4. Epub 2022 Jan 4. PMID: 34984596

Article Published Date : Jan 03, 2022

Study Type : Animal Study

Additional Links

Substances : Gotu Kola

Diseases : Aluminum Toxicity , Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Problem Substances : Aluminum

[+]

Chlorogenic acid supplementation shows its therapeutic ability by reducing the oxidative stress and neuroinflammation in MPTP-intoxicated mice.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Exp Aging Res. 2021 Aug 12:1-20. Epub 2021 Aug 12. PMID: 34384037

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Pubmed Data : Acta Histochem. 2018 Dec 17. Epub 2018 Dec 17. PMID: 30573341

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Pubmed Data : Transl Neurodegener. 2012 ;1(1):16. Epub 2012 Aug 20. PMID: 23210631

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Curcumin may be effective in preventing or slowing the progression of Parkinson's Disease.Sep 30, 2015

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Demethoxycurcumin ameliorates rotenone-induced toxicity.Dec 31, 2018

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Pubmed Data : Front Biosci (Elite Ed). 2019 01 1 ;11:1-11. Epub 2019 Jan 1. PMID: 30468633

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Demethoxycurcumin

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Rotenone

[+]

Dietary supplementation of walnut attenuated MPTP-induced impairment in a mouse model of Parkinson's disease.May 05, 2015

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Pubmed Data : Neurochem Res. 2015 May 6. Epub 2015 May 6. PMID: 25944473

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Fucoidan-rich substances in E. cava could be a potential material for improving cognitive function.Oct 16, 2019

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Pubmed Data : An Acad Bras Cienc. 2021 ;93(suppl 4):e20210481. Epub 2021 Nov 1. PMID: 34730624

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Coffee

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Plant Extracts

[+]

[+]

Hericium erinaceus and Coriolus versicolor modulate molecular and biochemical changes after traumatic brain injury.Jun 01, 2021

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Pubmed Data : Antioxidants (Basel). 2021 Jun 2 ;10(6). Epub 2021 Jun 2. PMID: 34199629

Article Published Date : Jun 01, 2021

Study Type : Animal Study

Additional Links

Substances : Lion's Mane (Hericium Erinaceus), Turkey Tail Mushroom

Diseases : Brain Injury: Traumatic, Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Hericium erinaceus may provide neuroprotective candidates for treating or preventing neurodegenerative diseases.Oct 31, 2016

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Pubmed Data : Int J Mol Sci. 2016 Nov 1 ;17(11). Epub 2016 Nov 1. PMID: 27809277

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Pubmed Data : Biomed Pharmacother. 2021 Apr 18 ;139:111525. Epub 2021 Apr 18. PMID: 33882412

Pubmed Data : Psychopharmacology (Berl). 2020 Nov ;237(11):3225-3236. Epub 2020 Jul 10. PMID: 32651640

Article Published Date : Oct 31, 2020

Study Type : Animal Study

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Substances : Flavonoids

Diseases : Parkinson's Disease

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Additional Keywords : Plant Extracts

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Korean Red Ginseng protects dopaminergic neurons in the ST by ameliorating MPTP-induced impairments in the animal model for PD.Dec 31, 2015

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Pubmed Data : PLoS One. 2014 ;9(9):e108034. Epub 2014 Sep 24. PMID: 25251220

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Pubmed Data : Neurotox Res. 2009 Feb;15(2):111-22. Epub 2009 Feb 20. PMID: 19384573

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Pubmed Data : Neurochem Int. 2013 Jun ;62(8):1039-47. Epub 2013 Apr 3. PMID: 23562769

Article Published Date : May 31, 2013

Study Type : Animal Study

Additional Links

Substances : Mucuna pruriens (aka Velvet Beans)

Diseases : Brain: Oxidative Stress, Parkinson's Disease

Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents

Additional Keywords : Plant Extracts

Problem Substances : Paraquat

[+]

Multitarget effects of Korean red ginseng in animal model of Parkinson's diseaseJun 30, 2018

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Pubmed Data : Int J Neurosci. 2018 Nov 15:1-7. Epub 2018 Nov 15. PMID: 30433834

Article Published Date : Nov 14, 2018

Study Type : Animal Study

Additional Links

Substances : Naringenin

Diseases : Brain: Oxidative Stress, Parkinson's Disease

Pharmacological Actions : Antioxidants, Neuroprotective Agents

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Naringin could be an alternative option in the management of Parkinson's disease.Jan 07, 2020

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Pubmed Data : Neuromolecular Med. 2020 Jan 8. Epub 2020 Jan 8. PMID: 31916219

Article Published Date : Jan 07, 2020

Study Type : Animal Study

Additional Links

Substances : Citrus naringin

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Rotenone

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Neuroprotective mechanisms of S-allyl-L-cysteine in neurological disease.Jan 31, 2020

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Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1565-1569. Epub 2019 Dec 27. PMID: 32010340

Article Published Date : Jan 31, 2020

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

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Neuroprotective nechanisms of three natural antioxidants on a rat model of Parkinson's disease.Jan 05, 2020

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Pubmed Data : Pharmacol Res. 2016 Nov ;113(Pt A):276-289. Epub 2016 Sep 8. PMID: 27616549

Article Published Date : Oct 31, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Palmitoylethanolamide

Diseases : Neurodegenerative Diseases, Oxidative Stress, Parkinson's Disease

Pharmacological Actions : Anti-Apoptotic, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation

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Phloretin attenuates behavior deficits and neuroinflammatory response in MPTP induced Parkinson's disease in mice.Jun 24, 2019

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Pubmed Data : Life Sci. 2019 Jun 25:116600. Epub 2019 Jun 25. PMID: 31251998

Article Published Date : Jun 24, 2019

Study Type : Animal Study

Additional Links

Substances : Phloretin

Diseases : Brain Inflammation , Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Photobiomodulation has potential as therapeutic tool for reducing vascular dysfunction in neurological conditions.Jan 03, 2019

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Pubmed Data : Biomolecules. 2019 10 4 ;9(10). Epub 2019 Oct 4. PMID: 31590236

Article Published Date : Jan 03, 2019

Study Type : Animal Study

Additional Links

Diseases : Neurologic Disorders, Parkinson's Disease

Therapeutic Actions : Laser Treatment: Low-Level

Pharmacological Actions : Neuroprotective Agents

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View the Evidence: 751 Abstracts with Parkinson's Disease Research

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A growing body of evidence supports qigong and tai chi performed as qigong as valid complementary or alternative therapeutic exercises.May 31, 2019

Baicalein exerts potential neuroprotective effects through multiple signaling pathways in animal models of Parkinson's disease.Dec 31, 2019

Effect of ginsenoside-Rg1 on experimental Parkinson's disease.May 31, 2021

Effectiveness of Tai Chi for health promotion for adults with health conditions: a scoping review of Meta-analyses.Feb 17, 2020

Occupational exposure to pesticides appears to increases the risk of Parkinson's disease.Sep 30, 2012

Parkinson's disease patients benefit from bicycling - a systematic review and meta-analysis.Sep 23, 2021

Qigong is a beneficial alternative therapy contributing to increasing motor function, walking ability, and balance for patients with Parkinson's disease.Nov 30, 2020

Reduced exposure to sunlight were significantly associated with an increased risk of Parkinson's disease.Jan 22, 2019

Tai Chi and Qigong is beneficial for improving motor function, depression and quality of life for individuals with Parkinson's disease.May 24, 2017

The impact of tai chi on motor function, balance, and quality of life in Parkinson's disease.Dec 31, 2020

This meta-analysis provided some evidence that melatonin improves sleep quality in patients with AD and PD.Aug 08, 2015

Vitamin E might have a protective effect against Parkinson's disease.May 20, 2021

"Tai chi training appears to reduce balance impairments in patients with mild-to-moderate Parkinson's disease, with additional benefits of improved functional capacity and reduced falls."Feb 09, 2012

A ketogenic diet has anticonvulsant and neuroprotective effects. Jan 01, 2010

A naturally occuring L-Dopa rich plant extract of Mucuna pruriens was found to be an effective treatment for patients with Parkinson's disease.Sep 01, 1995

A single bout of aerobic exercise improves motor skill consolidation in Parkinson's disease.Dec 31, 2017

Acupuncture in combination with Madopa may improve cerebral glucose metabolism in Parkinson's disease.Oct 01, 2007

Acute cannabidiol administration at a dose of 300 mg decreased anxiety in patients with Parkinson's disease.Jan 06, 2020

Ai Chi exercises should be considered as a rehabilitation option for treatment of patients with mild or moderate Parkinson's disease.Mar 31, 2018

Although hip bone mineral density is strongly related to hip fracture risk in elderly white women, other clinical risk factors also are independent predictors of long-term risk.Sep 01, 2004

An aquatic ai chi program appears to be a valid treatment option for patients diagnosed with mild to moderate Parkinson's disease for the treatment of pain.Nov 30, 2017

Aquatic Ai Chi applied twice weekly may potentially reduce Parkinsonian symptoms.Jan 31, 2018

Ascorbate status was positively associated with cognitive function in Parkinson's disease.Sep 22, 2020

Association between anticholinergic medication use and risk of dementia among patients with Parkinson's disease.Jun 27, 2019

Associations between long-term exposure to ambient air pollution and Parkinson's disease prevalence.Nov 28, 2019

Binaural-rhythmic sound may be a co-assistant tool in the treatment of Parkinson's disease.Nov 12, 2017

Blackcurrant anthocyanins has the potential to be developed to treat neurological conditions with IGF-1 deficiency.Jun 01, 2018

BPA glucuronidation was decreased in patients with Parkinson disease.Sep 19, 2017

Cannabidiol for rapid eye movement sleep behavior disorder. Mar 21, 2021

CBD may be effective, safe and well tolerated for the treatment of the psychosis in Parkinson's disease.Oct 31, 2009

Coenzyme Q10 appears to slow the progressive deterioration of function in Parkinson disease. Oct 01, 2002

Coenzyme Q10 may contribute to the pathophysiology of Parkinson's disease. Dec 05, 2008

Coenzyme Q10 supplementation provides mild symptomatic benefit in patients with Parkinson's disease.May 08, 2003

Combined acupuncture and bee venom might be safe and useful adjunctive treatment for patients with idiopathic Parkinson's disease.Jul 27, 2017

Combined treatment with acupuncture and bee venom acupuncture showed promising results as a safe adjunctive therapy for PD.Sep 30, 2015

Daily physical activity has beneficial effects on behaviour and cognitive function among adults with Parkinson's disease.May 31, 2017

Dietary vitamin B6 consumption is inversely correlated to risk for Parkinsons disease.Jul 25, 2006

Dysbiosis in Parkinson's disease might be triggered by certain antibiotics.Jan 08, 2020

Effect of home-based Tai Chi, Yoga or conventional balance exercise on functional balance and mobility among persons with idiopathic Parkinson’s disease.May 31, 2020

Electro-acupuncture add-on treatment markedly improves activity of daily living and quality of life of Parkinson's disease patients.Dec 31, 2014

Exposure to air pollution, especially PM2.5, was found to be related to incident Parkinson's disease in these results.Aug 15, 2018

Fecal short chain fatty acids concentrations were significantly reduced in PD patients compared to controls.Oct 31, 2016

Ginkgo biloba extract may attentuate the neurotoxic effects of levodopa in parkinson disease.Jan 01, 2003

Glyphosate has shown to be associated with the odds of premature mortality from Parkinson's disease.Dec 15, 2018

Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progression.May 31, 2019

High homocysteine levels are associated with neurodegenerative conditions such as Parkinson's disease, ALS and progressive supranuclear palsy.Jul 01, 2010

High homocysteine levels may be associated with the pathogenesis of neurological disorders.Jan 01, 2010

Higher total serum cholesterol concentrations are associated with a modest slower clinical progression of Parkinson's disease.Jan 01, 2011

Higher vitamin B12 level at Parkinson's disease diagnosis is associated with lower risk of future dementia.Mar 15, 2020

Homocysteine-lowering therapy may prevent bone loss in Parkinson's disease patients taking levodopa.Feb 15, 2010

Improved cognition while cycling in Parkinson's disease patients and healthy adults.Dec 31, 2016

L-dopa causes high homocysteine levels which may be prevented with B-vitamin supplementation.Sep 04, 2008

Low dose niacin supplementation may be beneficial in Parkinson's disease.Jul 14, 2018

Lymphocyte vitamin C levels as potential biomarker for progression of Parkinson's disease.Jan 31, 2015

Medical cannabis is considered as a therapeutic option by many Parkinson's disease patients.Nov 10, 2020

Melatonin levels are associated with hypothalamic gray matter volume loss and disease severity in PD patients. Mar 11, 2016

Mucuna pruriens is effective in treating the symptoms of Parkinson's disease, without the concomitant increase in dyskinesias that occurs with conventional L-dopa preparations.Dec 01, 2004

N-acetylcysteine is associated with dopaminergic improvement in Parkinson's disease.Sep 30, 2019

Neurotoxicity from pertussis infection may be casually related to the pathogenesis of Parkinson's disease.Dec 01, 1996

Participation in drum circles improved the symptoms and signs of Parkinson's disease (PD).Apr 30, 2016

Particulate matter plays a significant role in the development of Parkinson’s disease.Dec 31, 2016

Patients exposed to dental amalgam fillings were 1.583 times more likely to have Parkinson’s disease.Dec 31, 2015

Qigong exercise decreased TNF-α level in people with Parkinson's disease and helped improve sleep quality.Apr 22, 2017

Qigong exercise has the potential as a rehabilitation method for people with Parkinson's disease.Apr 30, 2020

Qigong exercises could reduce the symptoms of Parkinson's disease and improve the body functions in both the mild and moderate stages.Dec 31, 2015

Reflexology may limit further deteroration or maintain improvement of wellbeing in Parkinson's disease patients.May 01, 2010

Relaxation guided imagery can dramatically reduce Parkinson's disease tremor. Oct 30, 2009

Relaxation guided imagery reduces motor fluctuations in Parkinson's disease.Dec 31, 2013

Safety and tolerability of cannabidiol in Parkinson disease.Dec 31, 2019

Sam-e appears to be well tolerated and effect in the treatment of depression in Parkinson's disease.Nov 01, 2000

Separate or concurrent use of antiemetics and antipsychotics showed increased risks of Parkinson's disease.Dec 10, 2018

Serum levels of some carotenoids, α-carotene, β-carotene and lycopene, were lower in patients with Parkinson's disease.Mar 31, 2017

Parkinson's Disease

View the Evidence:
751 Abstracts with Parkinson's Disease Research