Parkinson's Disease

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191 Substances Researched for Parkinson's Disease
NameACCKFocus
Coenzyme Q101160Locked
Mucuna pruriens (aka Velvet Beans)1339Locked
Melatonin635Locked
Curcumin2129Locked
Bee Venom627Locked
B-complex322Locked
Anthocyanins220Locked
Flavonoids920Locked
Palmitoylethanolamide 518Locked
Cannabidiol616Locked
Resveratrol1014Locked
Ginkgo biloba213Locked
Vitamin B-6312Locked
Delta-tetrahydrocannabinol (THC)511Locked
Probiotics211Locked
Thymoquinone911Locked
Vitamin B-12211Locked
Alpha-Lipoic Acid110Locked
Black Currant110Locked
Cholesterol 110Locked
Coconut Oil110Locked
Culinary Herbs and Spices110Locked
Fish Oil110Locked
Fruit: All110Locked
Olive Oil110Locked
Prebiotics110Locked
Puerarin510Locked
SAMe (S-adenosylmethionine)110Locked
Vegetables: All 110Locked
Vitamin B-3 (Niacin)110Locked
Vitamin D110Locked
Cannabinoids 69Locked
EGCG (Epigallocatechin gallate)79Locked
Fucoidan59Locked
Naringenin 59Locked
Baicalein58Locked
Gastrodin48Locked
Ginseng (Korean)48Locked
Polyphenols78Locked
Chrysin36Locked
Crocin36Locked
Gotu Kola56Locked
Holy Basil26Locked
Amurensin G15Locked
Asiatic Acid35Locked
Astaxanthin45Locked
Beta-Caryophyllene35Locked
Demethoxycurcumin35Locked
Ginsenosides55Locked
Green Tea45Locked
Gynostemma35Locked
Honokiol35Locked
Nobiletin 35Locked
Phloretin15Locked
Piperine35Locked
Vanillin35Locked
Ashwagandha34Locked
Bacopa34Locked
Carvacrol24Locked
Catechin 34Locked
Dopa bean24Locked
Fisetin34Locked
Lion's Mane (Hericium Erinaceus)34Locked
Long Pepper24Locked
Paeoniflorin24Locked
Passion Flower24Locked
Quercetin34Locked
Saffron24Locked
Sesamin24Locked
Spirulina24Locked
Ursolic Acid24Locked
Verbascoside24Locked
Walnut24Locked
Agaricus Blazei23Locked
Astragaloside33Locked
Carnosic Acid33Locked
Chaenomeles speciosa23Locked
Chinese Skullcap 23Locked
Chlorogenic Acid23Locked
Echinacea23Locked
Folic Acid 23Locked
Geraniol 23Locked
Melanin: Bacterial23Locked
Multivitamin13Locked
Oleuropein33Locked
Piceatannol 23Locked
Spikenard23Locked
Stilbenes23Locked
Sulforaphane33Locked
Syrian rue23Locked
Tangeretin 23Locked
Tanshinone IIA23Locked
Vitamin C33Locked
6-Shogaol12Locked
Amla Fruit22Locked
Arctigenin12Locked
Ayahuasca12Locked
Beet12Locked
Berberine12Locked
Black Tea22Locked
Blackberry12Locked
Brown Rice: Pre-Germinated12Locked
Butyrate12Locked
Caffeic acid phenethyl ester12Locked
Cannabis22Locked
Cashew12Locked
Celery12Locked
Coffee22Locked
Cordyceps sinensis12Locked
Creatine12Locked
DHA (Docosahexaenoic Acid)12Locked
Diosgenin12Locked
Essential Oils: Unspecified12Locked
Ferulic acid12Locked
Genistein12Locked
Glutathione22Locked
Gold (nanoparticles)12Locked
Hesperidin12Locked
Hydrogen Water12Locked
Isoflavones12Locked
Isothiocyanate12Locked
Lupeol12Locked
Luteolin12Locked
Moringa oleifera12Locked
Myricetin12Locked
Nettle12Locked
Nigella sativa (aka Black Seed)22Locked
Noni12Locked
Octacosanol12Locked
Olive leaf extract12Locked
Omega-3 Fatty Acids12Locked
Piperlongumine 12Locked
Polyunsaturated Fatty Acids (PUFAs)22Locked
Psyllium12Locked
Purslane12Locked
Red Wine Extract22Locked
Reishi Mushroom12Locked
Rosemary22Locked
Rutin22Locked
Safranal12Locked
Seaweed: Brown 12Locked
Sesamol12Locked
Silibinin12Locked
Soy Protein 12Locked
St. Johns Wort12Locked
Tetrahydrocurcumin12Locked
Theanine22Locked
Thymol12Locked
Tocotrienol: Delta12Locked
Ubiquinol12Locked
Vitamin E12Locked
Vitexins12Locked
18β-Glycyrrhetinic Acid11Locked
Apigenin11Locked
Avocado11Locked
Bamboo11Locked
Blueberry11Locked
Cannabinoids: Synthetic11Locked
Chrysanthemum Indicum11Locked
Cocoa11Locked
Cordyceps Militaris11Locked
Cucurbitacin E 11Locked
Cumin11Locked
Cysteine (see N-Acetylcysteine)11Locked
Daidzein11Locked
Elderberry11Locked
Fenugreek11Locked
Garlic: Aged11Locked
Genipin11Locked
Ginseng11Locked
Glycyrrhiza uralensis11Locked
Goji11Locked
Isoliquiritigenin11Locked
Lycopene11Locked
Magnolol11Locked
Mangosteen11Locked
Medicinal Mushrooms11Locked
Mulberry11Locked
Neem11Locked
Olive11Locked
Punicalagin11Locked
Red Sage11Locked
Riboflavin (Vitamin B-2)11Locked
Rosemaric Acid11Locked
Rosmarinic acid11Locked
Selenium11Locked
Tauroursodeoxycholic acid11Locked
Tea11Locked
Theaflavins11Locked
Turmeric11Locked
Wine11Locked
23 Problem Substances Researched for Parkinson's Disease
NameACCKFocus
Pesticides525Locked
Rotenone916Locked
Glyphosate413Locked
Antipsychotic Drugs110Locked
Bisphenol A 110Locked
Dental Amalgams110Locked
Mercury110Locked
Paraquat37Locked
Chlorpyrifos23Locked
Aluminum Chloride12Locked
Aspartame12Locked
Glyphosate formulations12Locked
Lead12Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)12Locked
Roundup (herbicide)12Locked
Tamoxifen12Locked
Aluminum11Locked
Cholinesterase Inhibitor Drugs11Locked
Dimethoate11Locked
Donepezil (trade name Aricept)11Locked
Galantamine11Locked
Rivastigmine11Locked
Zineb11Locked
18 Therapeutic Actions Researched for Parkinson's Disease
NameACCKFocus
Qigong340Locked
Tai Chi340Locked
Acupuncture431Locked
Ai-Chi Aquatic Exercise 330Locked
Dancing220Locked
Electroacupuncture416Locked
Dietary Modification: Low Carbohydrate/Ketogenic313Locked
Exercise413Locked
Music312Locked
Drumming 110Locked
Massage/Therapeutic Touch110Locked
Relaxation Therapy 110Locked
Melodic Intonation Therapy 22Locked
Exercise: Aerobic11Locked
Fasting/Caloric Restriction11Locked
Meditation 11Locked
Mind-Body Therapies11Locked
Yoga11Locked
1 Problematic Actions Researched for Parkinson's Disease
NameACCKFocus
Vaccination: All13Locked
Related Topics

Parkinson's Disease is a Sub of the following Topic

View the Evidence:
610 Abstracts with Parkinson's Disease Research

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A growing body of evidence supports qigong and tai chi performed as qigong as valid complementary or alternative therapeutic exercises.May 31, 2019

Pubmed Data : Altern Ther Health Med. 2019 Jun 1. Epub 2019 Jun 1. PMID: 31221939
Article Published Date : May 31, 2019
Study Type : Meta Analysis
Additional Links
Diseases : Cancers: All, Cardiovascular Diseases, Chronic Obstructive Pulmonary Disease, Parkinson's Disease
Therapeutic Actions : Qigong, Tai Chi
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Effectiveness of Tai Chi for health promotion for adults with health conditions: a scoping review of Meta-analyses.Feb 17, 2020

Pubmed Data : Disabil Rehabil. 2020 Feb 18:1-12. Epub 2020 Feb 18. PMID: 32070137
Article Published Date : Feb 17, 2020
Study Type : Meta Analysis
Additional Links
Diseases : Chronic Obstructive Pulmonary Disease, Coronary Artery Disease, Depression, Heart Failure, Hypertension, Osteoarthritis, Parkinson's Disease
Additional Keywords : Risk Reduction
[+]

Occupational exposure to pesticides appears to increases the risk of Parkinson's disease.Sep 30, 2012

Pubmed Data : Environ Int. 2012 Oct 1 ;46:30-43. Epub 2012 Jun 13. PMID: 22698719
Article Published Date : Sep 30, 2012
Study Type : Meta Analysis
Additional Links
Diseases : Parkinson's Disease
Problem Substances : Pesticides
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Reduced exposure to sunlight were significantly associated with an increased risk of Parkinson's disease.Jan 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2019 Jan 23 ;25:666-674. Epub 2019 Jan 23. PMID: 30672512
Article Published Date : Jan 22, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Vitamin D
Diseases : Parkinson's Disease, Vitamin D Deficiency
Therapeutic Actions : Sunlight exposure
Additional Keywords : Increased Risk
[+]

Tai Chi and Qigong is beneficial for improving motor function, depression and quality of life for individuals with Parkinson's disease.May 24, 2017

Pubmed Data : Parkinsonism Relat Disord. 2017 May 25. Epub 2017 May 25. PMID: 28602515
Article Published Date : May 24, 2017
Study Type : Meta Analysis, Review
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Qigong, Tai Chi
[+]

This meta-analysis provided some evidence that melatonin improves sleep quality in patients with AD and PD.Aug 08, 2015

Pubmed Data : Neurol Sci. 2015 Aug 9. Epub 2015 Aug 9. PMID: 26255301
Article Published Date : Aug 08, 2015
Study Type : Meta Analysis
Additional Links
Substances : Melatonin
Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease
[+]

"Tai chi training appears to reduce balance impairments in patients with mild-to-moderate Parkinson's disease, with additional benefits of improved functional capacity and reduced falls."Feb 09, 2012

Pubmed Data : N Engl J Med. 2012 Feb 9 ;366(6):511-9. PMID: 22316445
Article Published Date : Feb 09, 2012
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease, Posture Disorders
Therapeutic Actions : Tai Chi
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A ketogenic diet has anticonvulsant and neuroprotective effects. Jan 01, 2010

Pubmed Data : Przegl Lek. 2010;67(3):205-12. PMID: 20687386
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Anticonvulsants, Neuroprotective Agents
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A naturally occuring L-Dopa rich plant extract of Mucuna pruriens was found to be an effective treatment for patients with Parkinson's disease.Sep 01, 1995

Pubmed Data : J Altern Complement Med. 1995 Fall;1(3):249-55. PMID: 9395621
Article Published Date : Sep 01, 1995
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

A single bout of aerobic exercise improves motor skill consolidation in Parkinson's disease.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Aging Neurosci. 2018 ;10:328. Epub 2018 Oct 22. PMID: 30405397
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Exercise: Aerobic, Exercise: Cycling
Pharmacological Actions : Neuroprotective Agents
[+]

Acupuncture in combination with Madopa may improve cerebral glucose metabolism in Parkinson's disease.Oct 01, 2007

Pubmed Data : Cardiovasc Hematol Agents Med Chem. 2007 Oct;5(4):295-9. PMID: 19922349
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Acupuncture
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Acute cannabidiol administration at a dose of 300 mg decreased anxiety in patients with Parkinson's disease.Jan 06, 2020

Pubmed Data : J Psychopharmacol. 2020 Jan 7:269881119895536. Epub 2020 Jan 7. PMID: 31909680
Article Published Date : Jan 06, 2020
Study Type : Human Study
Additional Links
Substances : Cannabidiol
Diseases : Anxiety, Parkinson's Disease
Pharmacological Actions : Anti-Anxiety Agents
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Ai Chi exercises should be considered as a rehabilitation option for treatment of patients with mild or moderate Parkinson's disease.Mar 31, 2018

Pubmed Data : Disabil Rehabil. 2018 Apr ;40(7):791-797. Epub 2017 Jan 13. PMID: 28084851
Article Published Date : Mar 31, 2018
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Ai-Chi Aquatic Exercise
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Although hip bone mineral density is strongly related to hip fracture risk in elderly white women, other clinical risk factors also are independent predictors of long-term risk.Sep 01, 2004

Pubmed Data : J Am Geriatr Soc. 2004 Sep;52(9):1479-86. PMID: 15341549
Article Published Date : Sep 01, 2004
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Diabetes Mellitus: Type 2, Hip Fracture, Osteoporosis, Parkinson's Disease, Vision Loss
Additional Keywords : Diseases that are Linked
[+]

An aquatic ai chi program appears to be a valid treatment option for patients diagnosed with mild to moderate Parkinson's disease for the treatment of pain.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Phys Rehabil Med. 2017 Dec ;53(6):825-832. Epub 2017 Jun 19. PMID: 28627861
Article Published Date : Nov 30, 2017
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Ai-Chi Aquatic Exercise
Pharmacological Actions : Analgesics
[+]

Aquatic Ai Chi applied twice weekly may potentially reduce Parkinsonian symptoms.Jan 31, 2018

Pubmed Data : Complement Ther Med. 2018 Feb ;36:147-153. Epub 2017 Dec 8. PMID: 29458923
Article Published Date : Jan 31, 2018
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Ai-Chi Aquatic Exercise
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Ascorbate status was positively associated with cognitive function in Parkinson's disease.Sep 22, 2020

Pubmed Data : Antioxidants (Basel). 2020 Sep 23 ;9(10). Epub 2020 Sep 23. PMID: 32977491
Article Published Date : Sep 22, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Parkinson's Disease, Vitamin C Deficiency
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Risk Factors
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Association between anticholinergic medication use and risk of dementia among patients with Parkinson's disease.Jun 27, 2019

Pubmed Data : Pharmacotherapy. 2019 Jun 28. Epub 2019 Jun 28. PMID: 31251824
Article Published Date : Jun 27, 2019
Study Type : Human Study
Additional Links
Diseases : Dementia, Parkinson's Disease
Additional Keywords : Increased Risk
Problem Substances : Cholinesterase Inhibitor Drugs
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Associations between long-term exposure to ambient air pollution and Parkinson's disease prevalence.Nov 28, 2019

Pubmed Data : Neurochem Int. 2019 Nov 29 ;133:104615. Epub 2019 Nov 29. PMID: 31786292
Article Published Date : Nov 28, 2019
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Parkinson's Disease
Additional Keywords : Risk Factors
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Binaural-rhythmic sound may be a co-assistant tool in the treatment of Parkinson's disease.Nov 12, 2017

Pubmed Data : Int J Neural Syst. 2017 Nov 13:1750055. Epub 2017 Nov 13. PMID: 29297265
Article Published Date : Nov 12, 2017
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Music
Pharmacological Actions : Neuroprotective Agents
[+]

Blackcurrant anthocyanins has the potential to be developed to treat neurological conditions with IGF-1 deficiency.Jun 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jun 2 ;10(6). Epub 2018 Jun 2. PMID: 29865234
Article Published Date : Jun 01, 2018
Study Type : Human Study
Additional Links
Substances : Anthocyanins, Black Currant
Diseases : Parkinson's Disease
Pharmacological Actions : Insulin-Like Growth Factor Inhibition/Downregulation, Neuroprotective Agents
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BPA glucuronidation was decreased in patients with Parkinson disease.Sep 19, 2017

Pubmed Data : Neurotoxicology. 2017 Sep 20 ;63:90-96. Epub 2017 Sep 20. PMID: 28939238
Article Published Date : Sep 19, 2017
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Problem Substances : Bisphenol A
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CBD may be effective, safe and well tolerated for the treatment of the psychosis in Parkinson's disease.Oct 31, 2009

Pubmed Data : J Psychopharmacol. 2009 Nov ;23(8):979-83. Epub 2008 Sep 18. PMID: 18801821
Article Published Date : Oct 31, 2009
Study Type : Human Study
Additional Links
Substances : Cannabidiol
Diseases : Parkinson's Disease, Psychoses
[+]

Coenzyme Q10 appears to slow the progressive deterioration of function in Parkinson disease. Oct 01, 2002

Pubmed Data : Arch Neurol. 2002 Oct;59(10):1541-50. PMID: 12374491
Article Published Date : Oct 01, 2002
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants
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Coenzyme Q10 may contribute to the pathophysiology of Parkinson's disease. Dec 05, 2008

Pubmed Data : Neurosci Lett. 2008 Dec 5;447(1):17-9. Epub 2008 Sep 30. PMID: 18840506
Article Published Date : Dec 05, 2008
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Parkinson's Disease
[+]

Coenzyme Q10 supplementation provides mild symptomatic benefit in patients with Parkinson's disease.May 08, 2003

Pubmed Data : Neurosci Lett. 2003 May 8;341(3):201-4. PMID: 12697283
Article Published Date : May 08, 2003
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Parkinson's Disease
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Combined acupuncture and bee venom might be safe and useful adjunctive treatment for patients with idiopathic Parkinson's disease.Jul 27, 2017

Pubmed Data : J Altern Complement Med. 2017 Jul 28. Epub 2017 Jul 28. PMID: 28753030
Article Published Date : Jul 27, 2017
Study Type : Human Study
Additional Links
Substances : Bee Venom
Diseases : Parkinson's Disease
Therapeutic Actions : Acupuncture
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Combined treatment with acupuncture and bee venom acupuncture showed promising results as a safe adjunctive therapy for PD.Sep 30, 2015

Pubmed Data : J Altern Complement Med. 2015 Oct ;21(10):598-603. Epub 2015 Jul 31. PMID: 26230989
Article Published Date : Sep 30, 2015
Study Type : Human Study
Additional Links
Substances : Bee Venom
Diseases : Parkinson's Disease
Therapeutic Actions : Acupuncture
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Daily physical activity has beneficial effects on behaviour and cognitive function among adults with Parkinson's disease.May 31, 2017

Pubmed Data : Disabil Health J. 2017 Jun 1. Epub 2017 Jun 1. PMID: 28596093
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Exercise
Pharmacological Actions : Neuroprotective Agents
[+]

Dietary vitamin B6 consumption is inversely correlated to risk for Parkinsons disease.Jul 25, 2006

Pubmed Data : Neurology. 2006 Jul 25;67(2):315-8. PMID: 16864826
Article Published Date : Jul 25, 2006
Study Type : Human Study
Additional Links
Substances : Vitamin B-6
Diseases : Parkinson's Disease
Additional Keywords : Risk Reduction
[+]

Dysbiosis in Parkinson's disease might be triggered by certain antibiotics.Jan 08, 2020

Pubmed Data : Med Hypotheses. 2020 Jan 9 ;137:109564. Epub 2020 Jan 9. PMID: 31954994
Article Published Date : Jan 08, 2020
Study Type : Human Study
Additional Links
Diseases : Antibiotic Toxicity , Dysbiosis, Parkinson's Disease
Additional Keywords : Risk Factors
Problem Substances : Antibiotics
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Effect of home-based Tai Chi, Yoga or conventional balance exercise on functional balance and mobility among persons with idiopathic Parkinson’s disease.May 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Hong Kong Physiother J. 2020 Jun ;40(1):39-49. Epub 2020 Feb 20. PMID: 32489239
Article Published Date : May 31, 2020
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Tai Chi
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Electro-acupuncture add-on treatment markedly improves activity of daily living and quality of life of Parkinson's disease patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:692795. Epub 2015 Aug 13. PMID: 26351515
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease, Quality of Life: Poor
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Nitric Oxide Inhibitor
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Exposure to air pollution, especially PM2.5, was found to be related to incident Parkinson's disease in these results.Aug 15, 2018

Pubmed Data : Int J Epidemiol. 2018 Aug 16. Epub 2018 Aug 16. PMID: 30124852
Article Published Date : Aug 15, 2018
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Parkinson's Disease
Additional Keywords : Risk Factors
[+]

Fecal short chain fatty acids concentrations were significantly reduced in PD patients compared to controls.Oct 31, 2016

Pubmed Data : Parkinsonism Relat Disord. 2016 Nov ;32:66-72. Epub 2016 Aug 26. PMID: 27591074
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Diseases : Dysbiosis, Parkinson's Disease
Additional Keywords : Microbiota, Risk Factors
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Ginkgo biloba extract may attentuate the neurotoxic effects of levodopa in parkinson disease.Jan 01, 2003

Pubmed Data : J Huazhong Univ Sci Technolog Med Sci. 2003;23(2):151-3. PMID: 12973934
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Substances : Ginkgo biloba
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Glyphosate has shown to be associated with the odds of premature mortality from Parkinson's disease.Dec 15, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2018 Dec 16 ;15(12). Epub 2018 Dec 16. PMID: 30558363
Article Published Date : Dec 15, 2018
Study Type : Human Study
Additional Links
Diseases : Glyphosate Toxicity, Parkinson's Disease
Additional Keywords : Increased Risk, Mortality
Problem Substances : Glyphosate
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Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progression.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EBioMedicine. 2019 Jun ;44:691-707. Epub 2019 Jun 18. PMID: 31221587
Article Published Date : May 31, 2019
Study Type : Human Study
Additional Links
Diseases : Dysbiosis, Parkinson's Disease
Additional Keywords : Risk Factors
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High homocysteine levels are associated with neurodegenerative conditions such as Parkinson's disease, ALS and progressive supranuclear palsy.Jul 01, 2010

Pubmed Data : Dement Geriatr Cogn Disord. 2010 Jul;29(6):553-9. Epub 2010 Jul 3. PMID: 20606437
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Diseases : Amyotrophic Lateral Sclerosis, Hyperhomocysteinemia, Parkinson's Disease, Supranuclear Palsy: Progressive
Additional Keywords : Diseases that are Linked
[+]

High homocysteine levels may be associated with the pathogenesis of neurological disorders.Jan 01, 2010

Pubmed Data : Front Biosci (Schol Ed). 2010;2:359-72. Epub 2010 Jan 1. PMID: 20036953
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : B-complex
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Epilepsy, High Homocysteine, Hyperhomocysteinemia, Multiple Sclerosis, Parkinson's Disease, Stroke
Additional Keywords : Diseases that are Linked
[+]

Higher total serum cholesterol concentrations are associated with a modest slower clinical progression of Parkinson's disease.Jan 01, 2011

Pubmed Data : PLoS One. 2011 ;6(8):e22854. Epub 2011 Aug 11. PMID: 21853051
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Cholesterol
Diseases : Parkinson's Disease
[+]

Higher vitamin B12 level at Parkinson's disease diagnosis is associated with lower risk of future dementia.Mar 15, 2020

Pubmed Data : Parkinsonism Relat Disord. 2020 Mar 16 ;73:19-22. Epub 2020 Mar 16. PMID: 32203914
Article Published Date : Mar 15, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : Dementia, Parkinson's Disease, Vitamin B 12 Deficiency
Pharmacological Actions : Neuroprotective Agents
[+]

Homocysteine-lowering therapy may prevent bone loss in Parkinson's disease patients taking levodopa.Feb 15, 2010

Pubmed Data : Mov Disord. 2010 Feb 15;25(3):332-40. PMID: 19938151
Article Published Date : Feb 15, 2010
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid, Vitamin B-12
Diseases : Homocystinuria, Parkinson's Disease
Pharmacological Actions : Antioxidants
Additional Keywords : Diseases that are Linked
[+]

Improved cognition while cycling in Parkinson's disease patients and healthy adults.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain Cogn. 2017 04 ;113:23-31. Epub 2017 Jan 11. PMID: 28088064
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Exercise: Cycling
Pharmacological Actions : Neuroprotective Agents
[+]

L-dopa causes high homocysteine levels which may be prevented with B-vitamin supplementation.Sep 04, 2008

Pubmed Data : Biometals. 2008 Sep 4. [Epub ahead of print] PMID: 14994447
Article Published Date : Sep 04, 2008
Study Type : Human Study
Additional Links
Substances : B-complex
Diseases : High Homocysteine, Parkinson's Disease
Additional Keywords : Diseases that are Linked
[+]

Low dose niacin supplementation may be beneficial in Parkinson's disease.Jul 14, 2018

Pubmed Data : J Neuroimmunol. 2018 Jul 15 ;320:76-79. Epub 2018 May 4. PMID: 29759143
Article Published Date : Jul 14, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Lymphocyte vitamin C levels as potential biomarker for progression of Parkinson's disease.Jan 31, 2015

Pubmed Data : Nutrition. 2015 Feb ;31(2):406-8. Epub 2014 Aug 23. PMID: 25592020
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Oxidative Stress, Parkinson's Disease, Vitamin C Deficiency
Additional Keywords : Risk Factors
[+]

Medical cannabis is considered as a therapeutic option by many Parkinson's disease patients.Nov 10, 2020

Pubmed Data : J Parkinsons Dis. 2020 Nov 11. Epub 2020 Nov 11. PMID: 33216043
Article Published Date : Nov 10, 2020
Study Type : Human Study
Additional Links
Substances : Cannabis
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Melatonin levels are associated with hypothalamic gray matter volume loss and disease severity in PD patients. Mar 11, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mov Disord. 2016 Mar 12. Epub 2016 Mar 12. PMID: 26971528
Article Published Date : Mar 11, 2016
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Circadian Dysregulation, Parkinson's Disease
Additional Keywords : Risk Factors
[+]

Mucuna pruriens is effective in treating the symptoms of Parkinson's disease, without the concomitant increase in dyskinesias that occurs with conventional L-dopa preparations.Dec 01, 2004

Pubmed Data : J Neurol Neurosurg Psychiatry. 2004 Dec;75(12):1672-7. PMID: 15548480
Article Published Date : Dec 01, 2004
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

N-acetylcysteine is associated with dopaminergic improvement in Parkinson's disease.Sep 30, 2019

Pubmed Data : Clin Pharmacol Ther. 2019 Oct ;106(4):884-890. Epub 2019 Jul 17. PMID: 31206613
Article Published Date : Sep 30, 2019
Study Type : Human Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neurotoxicity from pertussis infection may be casually related to the pathogenesis of Parkinson's disease.Dec 01, 1996

Pubmed Data : Int J Epidemiol. 1996 Dec;25(6):1301-11. PMID: 9027539
Article Published Date : Dec 01, 1996
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease, Pertussis, Whooping Cough
Additional Keywords : Diseases that are Linked
[+]

Participation in drum circles improved the symptoms and signs of Parkinson's disease (PD).Apr 30, 2016

Pubmed Data : Mov Disord Clin Pract. 2016 May-Jun;3(3):243-249. Epub 2015 Dec 21. PMID: 27340683
Article Published Date : Apr 30, 2016
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Drumming
[+]

Particulate matter plays a significant role in the development of Parkinson’s disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(8):e0182834. Epub 2017 Aug 15. PMID: 28809934
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Parkinson's Disease
Additional Keywords : Risk Factors
[+]

Patients exposed to dental amalgam fillings were 1.583 times more likely to have Parkinson’s disease.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(12):e0166552. Epub 2016 Dec 1. PMID: 27906991
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Additional Keywords : Risk Factors
Problem Substances : Dental Amalgams, Mercury
[+]

Qigong exercise decreased TNF-α level in people with Parkinson's disease and helped improve sleep quality.Apr 22, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2017 Apr 23 ;4(2). Epub 2017 Apr 23. PMID: 28930237
Article Published Date : Apr 22, 2017
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Qigong
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Qigong exercises could reduce the symptoms of Parkinson's disease and improve the body functions in both the mild and moderate stages.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:5935782. Epub 2016 Nov 7. PMID: 27891159
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Qigong
[+]

Reflexology may limit further deteroration or maintain improvement of wellbeing in Parkinson's disease patients.May 01, 2010

Pubmed Data : Complement Ther Clin Pract. 2010 May;16(2):96-100. Epub 2009 Nov 4. PMID: 20347841
Article Published Date : May 01, 2010
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Massage/Therapeutic Touch
[+]

Relaxation guided imagery can dramatically reduce Parkinson's disease tremor. Oct 30, 2009

Pubmed Data : Mov Disord. 2009 Oct 30;24(14):2059-62. PMID: 19768725
Article Published Date : Oct 30, 2009
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease, Tremor
Therapeutic Actions : Relaxation Therapy
[+]

Relaxation guided imagery reduces motor fluctuations in Parkinson's disease.Dec 31, 2013

Pubmed Data : J Parkinsons Dis. 2014 ;4(3):431-6. PMID: 24685702
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Guided Imagery
[+]

Sam-e appears to be well tolerated and effect in the treatment of depression in Parkinson's disease.Nov 01, 2000

Pubmed Data : Mov Disord. 2000 Nov;15(6):1225-9. PMID: 11104210
Article Published Date : Nov 01, 2000
Study Type : Human Study
Additional Links
Substances : SAMe (S-adenosylmethionine)
Diseases : Parkinson's Disease
[+]

Separate or concurrent use of antiemetics and antipsychotics showed increased risks of Parkinson's disease.Dec 10, 2018

Pubmed Data : Int J Clin Pharmacol Ther. 2018 Dec 11. Epub 2018 Dec 11. PMID: 30526811
Article Published Date : Dec 10, 2018
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Additional Keywords : Increased Risk
Problem Substances : Antipsychotic Drugs
[+]

Serum levels of some carotenoids, α-carotene, β-carotene and lycopene, were lower in patients with Parkinson's disease.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2017 Apr ;11(2):114-120. Epub 2016 Dec 15. PMID: 28386384
Article Published Date : Mar 31, 2017
Study Type : Human Study
Additional Links
Diseases : Carotenoid Deficiency, Parkinson's Disease, Vitamin E Deficiency
[+]

Short duration, intensive tango dancing is an appropriate and effective treatment for patients with mild to moderately severe Parkinson disease. Oct 01, 1996

Pubmed Data : Planta Med. 1996 Oct;62(5):405-9. PMID: 19632547
Article Published Date : Oct 01, 1996
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Dancing
[+]

Structural changes of gut microbiota in Parkinson's disease and its correlation with clinical features.May 19, 2017

Pubmed Data : Sci China Life Sci. 2017 May 20. Epub 2017 May 20. PMID: 28536926
Article Published Date : May 19, 2017
Study Type : Human Study
Additional Links
Diseases : Dysbiosis, Parkinson's Disease
Additional Keywords : Microbiota
[+]

Supplementary management with Pycnogenol® in Parkinson's disease to prevent cognitive impairment.Jan 19, 2020

Pubmed Data : J Neurosurg Sci. 2020 Jan 20. Epub 2020 Jan 20. PMID: 31957998
Article Published Date : Jan 19, 2020
Study Type : Human Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Tai Chi appears to be an appropriate, safe and effective form of exercise for some individuals with mild-moderately severe Parkinson disease.Oct 01, 2008

Pubmed Data : Gait Posture. 2008 Oct;28(3):456-60. Epub 2008 Apr 18. PMID: 18378456
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Tai Chi
[+]

Tai Chi had the potential to slow down the progression of symptoms of Parkinson's disease and delayed the introduction of levodopa.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz J Med Biol Res. 2020 ;53(2):e9171. Epub 2020 Feb 10. PMID: 32049101
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Tai Chi
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Risk Reduction
[+]

Tai Chi plus routine exercise might be an alternative non-pharmacological approach for the motor and non-motor symptoms of Parkinson's disease patients.Oct 24, 2019

Pubmed Data : J Sports Med Phys Fitness. 2019 Oct 25. Epub 2019 Oct 25. PMID: 31665879
Article Published Date : Oct 24, 2019
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Tai Chi
[+]

Tango lessons improve balance, endurance, balance confidence, and quality of life in a participant with severe Parkinson disease.Jan 01, 2010

Pubmed Data : Disabil Rehabil. 2010;32(8):679-84. PMID: 20205582
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease, Quality of Life: Poor
Therapeutic Actions : Dancing
[+]

The aquatic exercise program induced functional improvement in individuals with Parkinson's disease.Aug 13, 2020

Pubmed Data : Physiol Behav. 2020 Aug 14 ;227:113135. Epub 2020 Aug 14. PMID: 32798568
Article Published Date : Aug 13, 2020
Study Type : Human Study
Additional Links
Substances : Grape
Diseases : Parkinson's Disease
Therapeutic Actions : Exercise
Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents
Additional Keywords : Epigenetic Modification
[+]

The combination of carvacrol and exercise could be an effective therapeutic tool for treatment of neurobehavioral deficits in Parkinson's disease patients.Jul 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arq Neuropsiquiatr. 2019 Jul 29 ;77(7):493-500. Epub 2019 Jul 29. PMID: 31365641
Article Published Date : Jul 28, 2019
Study Type : Human Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Therapeutic Actions : Exercise
Pharmacological Actions : Neuroprotective Agents
[+]

The consumption of a fermented milk containing multiple probiotic strains and prebiotic fiber could improve constipation in patients with PD.Aug 18, 2016

Pubmed Data : Neurology. 2016 Aug 19. Epub 2016 Aug 19. PMID: 27543643
Article Published Date : Aug 18, 2016
Study Type : Human Study
Additional Links
Substances : Prebiotics, Probiotics
Diseases : Constipation, Parkinson's Disease
Pharmacological Actions : Laxative
[+]

These are the first data to provide evidence that targeted nutrition is associated with the rate of Parkinson's disease progression.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:6405278. Epub 2017 Sep 10. PMID: 29081890
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Coconut Oil, Coenzyme Q10, Culinary Herbs and Spices, Fish Oil, Fruit: All, Olive Oil, Vegetables: All
Diseases : Parkinson's Disease
Additional Keywords : Increased Risk, Risk Reduction
[+]

These findings provide evidence of a possible association between endothelial dysfunction as assessed by FMD and low vitamin D status in patients with early PD.Sep 04, 2015

Pubmed Data : J Neural Transm. 2015 Sep 5. Epub 2015 Sep 5. PMID: 26343034
Article Published Date : Sep 04, 2015
Study Type : Human Study
Additional Links
Diseases : Endothelial Dysfunction, Parkinson's Disease, Vitamin D Deficiency
[+]

These findings suggest that the intake of some flavonoids may reduce Parkinson’s disease risk.Apr 09, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurology. 2012 Apr 10 ;78(15):1138-45. Epub 2012 Apr 4. PMID: 22491871
Article Published Date : Apr 09, 2012
Study Type : Human Study
Additional Links
Substances : Anthocyanins, Flavonoids
Diseases : Parkinson's Disease
Additional Keywords : Risk Reduction
[+]

These results provide fresh insights into the ambiguous association between T. gondii infection and Parkinson's disease.Jun 07, 2017

Pubmed Data : Acta Trop. 2017 Jun 8. Epub 2017 Jun 8. PMID: 28602836
Article Published Date : Jun 07, 2017
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease, Toxoplasma gondii Infection
Additional Keywords : Risk Factors
[+]

This is the first report showing that ubiquinol-10 may significantly improve Parkinson's disease.Jul 31, 2015

Pubmed Data : Parkinsonism Relat Disord. 2015 Aug ;21(8):911-6. Epub 2015 May 29. PMID: 26054881
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Ultra-micronized palmitoylethanolamide slowed down disease progression and disability in Parkinson's disease patients.Dec 31, 2016

Pubmed Data : CNS Neurol Disord Drug Targets. 2017 ;16(6):705-713. PMID: 28325153
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Unexpected dual task benefits on cycling in Parkinson disease and healthy adults: a neuro-behavioral model.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(5):e0125470. Epub 2015 May 13. PMID: 25970607
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Exercise: Cycling
Pharmacological Actions : Neuroprotective Agents
[+]

Vitamin D3 supplementation may stabilize PD for a short period in patients with FokI TT or CT genotypes without triggering hypercalcemia.Apr 30, 2013

Pubmed Data : Am J Clin Nutr. 2013 May ;97(5):1004-13. Epub 2013 Mar 13. PMID: 23485413
Article Published Date : Apr 30, 2013
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Parkinson's Disease
[+]

Yoga meditation enhances proprioception and balance in individuals diagnosed with Parkinson's disease.Aug 02, 2020

Pubmed Data : Percept Mot Skills. 2020 Aug 3:31512520945085. Epub 2020 Aug 3. PMID: 32746736
Article Published Date : Aug 02, 2020
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Yoga
[+]

Administration of O. sanctum ethanolic extract may stimulate and restore the expression of choline acetyltransferase on the deteriorating cells of HCMECs.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet World. 2016 Dec ;9(12):1348-1354. Epub 2016 Dec 3. PMID: 28096604
Article Published Date : Nov 30, 2016
Study Type : Human In Vitro
Additional Links
Substances : Holy Basil
Diseases : Alzheimer's Disease, Dementia, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Amurensin G induces autophagy and attenuates cellular toxicities in a rotenone model of Parkinson's disease.Mar 28, 2013

Pubmed Data : Biochem Biophys Res Commun. 2013 Mar 29 ;433(1):121-6. Epub 2013 Feb 26. PMID: 23485458
Article Published Date : Mar 28, 2013
Study Type : Human In Vitro
Additional Links
Substances : Amurensin G
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Phytotherapy
Problem Substances : Rotenone
[+]

Neurorescue activity, APP regulation and amyloid-beta peptide reduction by novel multi-functional brain permeable iron- chelating- antioxidants, M-30 and green tea polyphenol, EGCG.Sep 01, 2007

Pubmed Data : Curr Alzheimer Res. 2007 Sep ;4(4):403-11. PMID: 17908043
Article Published Date : Sep 01, 2007
Study Type : Human In Vitro
Additional Links
Substances : Catechin
Diseases : Amyotrophic Lateral Sclerosis, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Regenerative
Additional Keywords : Nerve Regeneration
[+]

Phloretin has neuroprotective effects on rotenone-induced toxicity in human SH-SY5Y neuronal-like cells.Jul 07, 2017

Pubmed Data : Biofactors. 2017 Jul 8 ;43(4):549-557. Epub 2017 Apr 12. PMID: 28401997
Article Published Date : Jul 07, 2017
Study Type : Human In Vitro
Additional Links
Substances : Phloretin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

THC exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.Sep 30, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropathol Appl Neurobiol. 2012 Oct ;38(6):535-47. PMID: 22236282
Article Published Date : Sep 30, 2012
Study Type : Human In Vitro
Additional Links
Substances : Delta-tetrahydrocannabinol (THC)
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Ginkgo biloba and/or a multivitamin-multimineral supplement effected remarkable improvement in symptoms in this case report. Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Glob Adv Health Med. 2014 Jul ;3(4):43-4. PMID: 25105077
Article Published Date : Jun 30, 2014
Study Type : Human: Case Report
Additional Links
Substances : Ginkgo biloba, Multivitamin
Diseases : Parkinson's Disease, Parkinsonian Disorders
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Parkinson's disease due to laboral exposition to paraquatOct 31, 2012

Pubmed Data : Rev Med Inst Mex Seguro Soc. 2012 Nov-Dec;50(6):665-72. PMID: 23331754
Article Published Date : Oct 31, 2012
Study Type : Human: Case Report
Additional Links
Diseases : Parkinson's Disease
Problem Substances : Paraquat
Adverse Pharmacological Actions : Neurotoxic
[+]

Three case studies of post-vaccinal parkinsonism.Nov 30, 2002

Pubmed Data : Med Hypotheses. 2002 Dec ;59(6):762-9. PMID: 12445523
Article Published Date : Nov 30, 2002
Study Type : Human: Case Report
Additional Links
Diseases : Parkinson's Disease
Anti Therapeutic Actions : Vaccination: All
[+]

Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides.Jul 15, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Anim. 2020 Jul 16. Epub 2020 Jul 16. PMID: 32669479
Article Published Date : Jul 15, 2020
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ellagic acid protects dopamine neurons from rotenone-induced neurotoxicity via activation of Nrf2 signalling Jul 11, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2020 Jul 12. Epub 2020 Jul 12. PMID: 32657027
Article Published Date : Jul 11, 2020
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents, Nrf2 activation
Problem Substances : Rotenone
[+]

"Fucoidan protects against dopaminergic neuron death in vivo and in vitro."Aug 31, 2009

Pubmed Data : Eur J Pharmacol. 2009 Sep 1 ;617(1-3):33-40. Epub 2009 Jun 21. PMID: 19545563
Article Published Date : Aug 31, 2009
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Dopamine Deficiency, Parkinson's Disease
Pharmacological Actions : Antioxidants, Apoptotic, Neuroprotective Agents
[+]

6-Shogaol exerts neuroprotective effects on dopaminergic neurons in vitro and in vivo parkinson's disease models.Aug 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Pharmacol Sin. 2013 Sep ;34(9):1131-9. Epub 2013 Jul 1. PMID: 23811724
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : 6-Shogaol
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

A compound extracted from Chinese skullcap known as baicalein has neuroprotective effects in experimental parkinsonianism in vivo and in vitro. Jun 01, 2009

Pubmed Data : Pharmacol Biochem Behav. 2009 Jun;92(4):642-8. Epub 2009 Mar 25. PMID: 19327378
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Parkinson's Disease, Parkinsonism
[+]

A dihydroflavonoid naringin extends the lifespan of C. elegans and delays the progression of aging-related diseases.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:6069354. Epub 2020 Jul 31. PMID: 32832002
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Aging, Alzheimer's Disease, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

A polysaccharide obtained from Spirulina platensis plays a protective role against the MPTP-induced loss of dopaminergic neurons in C57BL/6J mice.Jan 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2015 Feb ;10(2):308-13. PMID: 25883632
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

A relatively low dose berberine exhibited strong neuroprotective activity against 6-OHDA-induced neurotoxicity in PC12 cells.Nov 03, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Redox Biol. 2016 Nov 4 ;11:1-11. Epub 2016 Aug 4. PMID: 27835779
Article Published Date : Nov 03, 2016
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

A walnut extract has neuroprotective effects and may have potential for the prevention or treatment of Parkinson’s disease.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 ;17(1). Epub 2016 Jan 15. PMID: 26784178
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Walnut
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

A water extract of Mucuna pruriens provides long-term amelioration of parkinsonism with reduced risk for dyskinesias.Aug 01, 2010

Pubmed Data : Parkinsonism Relat Disord. 2010 Aug;16(7):458-65. Epub 2010 May 31. PMID: 20570206
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Dopa bean
Diseases : Dyskinesia Syndromes, Parkinson's Disease, Parkinsonian Disorders
[+]

A. blazei extract offers a promising and new therapeutic lead for treatment of Parkinson's disease.Jun 18, 2017

Pubmed Data : Nutr Neurosci. 2017 Jun 19:1-10. Epub 2017 Jun 19. PMID: 28628424
Article Published Date : Jun 18, 2017
Study Type : Animal Study
Additional Links
Substances : Agaricus Blazei
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Acteoside protects against 6-OHDA-induced dopaminergic neuron damage.Aug 31, 2018

Pubmed Data : Food Chem Toxicol. 2018 Sep ;119:6-13. Epub 2018 Jun 12. PMID: 29906474
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Verbascoside
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Acupuncture inhibits the increase in alpha-synuclein in substantia nigra in an MPTP-induced Parkinsonism.Dec 31, 2019

Pubmed Data : Adv Exp Med Biol. 2020 ;1232:401-408. PMID: 31893437
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Acupuncture
Pharmacological Actions : Neuroprotective Agents
[+]

An Echinacea compound exhibits neuroprotective effects n the mouse model of Parkinson's disease. Jun 14, 2007

Pubmed Data : Eur J Pharmacol. 2007 Jun 14;564(1-3):66-74. Epub 2007 Feb 16. PMID: 17359968
Article Published Date : Jun 14, 2007
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Parkinson's Disease
[+]

Anacardic acids in cashew nuts have promising neuroprotective action against degenerative changes in Parkinson's disease.Jul 31, 2018

Pubmed Data : Neurotox Res. 2018 Aug ;34(2):250-262. Epub 2018 Mar 8. PMID: 29520721
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Cashew
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Anti-inflammatory activity of ursolic acid in MPTP-induced parkinsonian mouse model.Apr 22, 2019

Pubmed Data : Neurotox Res. 2019 Apr 23. Epub 2019 Apr 23. PMID: 31016688
Article Published Date : Apr 22, 2019
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Anti-inflammatory and anti-oxidant activity of Hidroxin in rotenone-induced Parkinson's disease.Sep 02, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Sep 3 ;9(9). Epub 2020 Sep 3. PMID: 32899274
Article Published Date : Sep 02, 2020
Study Type : Animal Study
Additional Links
Substances : Hydroxytyrosol
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Antioxidants inhibit neuronal toxicity in leucine-rich repeat kinase-2-linked Parkinson's disease. Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Clin Transl Neurol. 2016 Apr ;3(4):288-94. Epub 2016 Mar 2. PMID: 27081659
Article Published Date : Mar 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Piceatannol , Thymoquinone
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Apium graveolens extracts could offer a novel approach to the treatment of Parkinsonism.Mar 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Mar 20 ;18(1):103. Epub 2018 Mar 20. PMID: 29558946
Article Published Date : Mar 19, 2018
Study Type : Animal Study
Additional Links
Substances : Celery
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Arctigenin effectively provides protection against learning and memory deficits.May 24, 2016

Pubmed Data : Planta Med. 2016 May 25. Epub 2016 May 25. PMID: 27224270
Article Published Date : May 24, 2016
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Learning disorders, Memory Disorders, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Ashwaganda attenuates 6-hydroxydopamine induced Parkinsonism in rats.Mar 01, 2005

Pubmed Data : Hum Exp Toxicol. 2005 Mar;24(3):137-47. PMID: 15901053
Article Published Date : Mar 01, 2005
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Parkinson's Disease
[+]

Asiatic acid is a potent nutraceutical agent against the progression of Parkinson's disease.Mar 31, 2016

Pubmed Data : Food Funct. 2016 Apr ;7(4):1999-2005. PMID: 26999333
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Asiatic acid prevents oxidative stress and apoptosis by inhibiting the translocation of α-synuclein into mitochondria.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2018 ;12:431. Epub 2018 Jun 28. PMID: 30002614
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Astaxanthin is neuroprotective in an aged mouse model of Parkinson's disease.Feb 12, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2018 Feb 13 ;9(12):10388-10401. Epub 2017 Dec 28. PMID: 29535814
Article Published Date : Feb 12, 2018
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Astragaloside -IV prevents dopaminergic neurodegeneration in Parkinson's disease.Apr 05, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2020 Apr 6 ;17(1):105. Epub 2020 Apr 6. PMID: 32252767
Article Published Date : Apr 05, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Astragaloside IV protects dopaminergic neuron from neuroinflammation and oxidative stress.Sep 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 Oct ;75:105651. Epub 2019 Aug 8. PMID: 31401385
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

B. vulgaris significantly reduced the symptoms of parkinson's disease in animals.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2015 Jul-Aug;47(4):403-8. PMID: 26288473
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Beet
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Bacopa monnieri alleviates paraquat induced toxicity in Drosophila.Nov 30, 2018

Pubmed Data : Neurochem Int. 2018 Dec ;121:98-107. Epub 2018 Oct 5. PMID: 30296463
Article Published Date : Nov 30, 2018
Study Type : Insect Study
Additional Links
Substances : Bacopa
Diseases : Parkinson's Disease, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Paraquat
[+]

Bacterial melanin increases electrical activity of neurons in Substantia Nigra pars compacta.Dec 31, 2013

Pubmed Data : J Neural Transm. 2014 ;121(3):259-65. PMID: 25006618
Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Substances : Melanin: Bacterial
Diseases : Parkinson's Disease, Substantia Nigra: Damage
Pharmacological Actions : Neurorestorative
[+]

Baicalein could prevent the progression of α-syn accumulation in a Parkinson’s disease mouse model.Sep 30, 2016

Pubmed Data : Biochim Biophys Acta. 2016 Oct ;1862(10):1883-90. Epub 2016 Jul 15. PMID: 27425033
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Baicalein may be effective in the treatment of Parkinson's disease through anti-neuroinflammation.Aug 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Sep ;50:38-47. Epub 2017 Jun 15. PMID: 28623717
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Baicalein possesses anti-inflammatory activities by inhibiting α-synuclein aggregation, inflammasome activation and cathepsin B production.Oct 10, 2016

Pubmed Data : J Ethnopharmacol. 2016 Oct 11. Epub 2016 Aug 11. PMID: 27742410
Article Published Date : Oct 10, 2016
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Bee venom could be considered a potential therapeutic or preventive agent for PD and other neuroinflammatory associated disorders.Jul 27, 2016

Pubmed Data : Arch Pharm Res. 2016 Jul 28. Epub 2016 Jul 28. PMID: 27469335
Article Published Date : Jul 27, 2016
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Alzheimer's Disease, Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Bee venom phospholipase A2 protects dopaminergic neurons by modulating neuro-inflammatory responses in a mouse model of Parkinson's disease.Nov 14, 2015

Pubmed Data : J Immunol. 2015 Nov 15 ;195(10):4853-60. Epub 2015 Oct 9. PMID: 26453752
Article Published Date : Nov 14, 2015
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Beta-caryophyllene may be viewed as a potential treatment or preventative agent for Parkinson's disease.Jul 05, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2017 Jul 6 ;10(3). Epub 2017 Jul 6. PMID: 28684694
Article Published Date : Jul 05, 2017
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Biochanin A exerts protective effects on lipopolysaccharide-induced Parkinson's disease.Jan 09, 2016

Pubmed Data : Neurotox Res. 2016 10 ;30(3):486-98. Epub 2016 Jul 14. PMID: 27417698
Article Published Date : Jan 09, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Biochanin A
Diseases : Lipopolysaccharide-Induced Toxicity, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Bisphenol A exposure is involved in the development of Parkinson like disease in Drosophila melanogaster.Jan 13, 2020

Pubmed Data : Food Chem Toxicol. 2020 Jan 14 ;137:111128. Epub 2020 Jan 14. PMID: 31952986
Article Published Date : Jan 13, 2020
Study Type : Insect Study
Additional Links
Diseases : Bisphenol Toxicity, Parkinson's Disease
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
[+]

Both curcumin and its metabolite tetrahydrocurcumin exert neuroprotection against chemically-induced neurotoxicity.Apr 01, 2008

Pubmed Data : Inflammopharmacology. 2008 Apr;16(2):96-9. PMID: 18408903
Article Published Date : Apr 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin, Flavonoids, Polyphenols, Tetrahydrocurcumin
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Caffeic acid phenethyl ester prevented the neurodegenerations in brain tissue in chlorpyrifos induced Parkinson's disease.Dec 31, 2017

Pubmed Data : Pestic Biochem Physiol. 2018 Jan ;144:36-41. Epub 2017 Nov 10. PMID: 29463406
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Parkinson's Disease, Pesticide Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Chlorpyrifos
[+]

Cannabidiol is able to attenuate motor and cognitive impairments induced by reserpine.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:343. Epub 2016 Aug 28. PMID: 27733830
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Memory Disorders: Drug-Induced, Parkinson's Disease, Tardive Dyskinesia
Pharmacological Actions : Neuroprotective Agents
[+]

Carvacrol promotes neuroprotection in the mouse hemiparkinsonian model.Jan 24, 2017

Pubmed Data : Neuroscience. 2017 07 25 ;356:176-181. Epub 2017 May 17. PMID: 28526576
Article Published Date : Jan 24, 2017
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Carvacrol protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro models of Parkinson's disease.Jul 29, 2019

Pubmed Data : Neurotox Res. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31364033
Article Published Date : Jul 29, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents
[+]

Celastrol may help to prevent and treat Parkinson's disease.Dec 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Dec 31 ;9(1). Epub 2019 Dec 31. PMID: 31906147
Article Published Date : Dec 30, 2019
Study Type : Animal Study
Additional Links
Substances : Celastrol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Chlorogenic acid supplementation shows its therapeutic ability by reducing the oxidative stress and neuroinflammation in MPTP-intoxicated mice.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:757. Epub 2018 Aug 6. PMID: 30127737
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Chronic treatment with carvacrol improves passive avoidance memory in a rat model of Parkinson's disease.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arq Neuropsiquiatr. 2018 Feb ;76(2):71-77. PMID: 29489959
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Chrysin exerts beneficial effects to Parkinson's disease.Jul 05, 2016

Pubmed Data : J Agric Food Chem. 2016 Jul 6 ;64(26):5324-33. Epub 2016 Jun 21. PMID: 27245668
Article Published Date : Jul 05, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chrysin
Diseases : Parkinson's Disease
Pharmacological Actions : Monoamine Oxidase Inhibitors, Neuroprotective Agents
[+]

Chrysin improved several behavioural, cognitive and neurochemical parameters in a relevant preclinical model of Parkinson's disease.Jan 26, 2019

Pubmed Data : Neurosci Lett. 2019 07 27 ;706:158-163. Epub 2019 May 20. PMID: 31121284
Article Published Date : Jan 26, 2019
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Chrysin restores MPTP induced neuroinflammation, oxidative stress and neurotrophic factors in an acute Parkinson's disease mouse model.Sep 13, 2019

Pubmed Data : Neurosci Lett. 2019 Sep 14 ;709:134382. Epub 2019 Jul 17. PMID: 31325581
Article Published Date : Sep 13, 2019
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Coenzyme Q10 has a neuroprotective effect in an experimental model of Parkinson's disease.Mar 01, 2008

Pubmed Data : J Neurochem. 2008 Mar;104(6):1613-21. Epub 2007 Oct 31. PMID: 17973981
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Coenzyme Q10 prevents paraquat-induced oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats.Jan 01, 2009

Pubmed Data : BMC Neurosci. 2009;10:88. Epub 2009 Jul 27. PMID: 19635141
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Oxidative Stress, Parkinson's Disease, Parkinsonian Disorders
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Combination therapy using CoQ(10) and creatine may be useful in the treatment of neurodegenerative diseases such as Parkinson's disease and Huntington Disease.Jun 01, 2009

Pubmed Data : J Neurochem. 2009 Jun;109(5):1427-39. Epub 2009 Mar 28. PMID: 19476553
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10, Creatine
Diseases : Huntington Disease, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
[+]

Common flowering quince, the fruit of Chaenomeles speciosa, may have therapeutic value in the treatment of Parkinson disease and Parkinsonian disorders. Sep 01, 2008

Pubmed Data : Pharmacol Biochem Behav. 2008 Sep;90(3):363-71. Epub 2008 Mar 30. PMID: 18485464
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Chaenomeles speciosa
Diseases : Parkinson's Disease
[+]

CoQ10 may be beneficial in slowing the progression of Parkinson's disease.Jan 31, 2018

Pubmed Data : Behav Pharmacol. 2018 Feb ;29(1):79-86. PMID: 28902670
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Cordycepin mitigates MPTP-induced Parkinson's disease through inhibiting TLR/NF-κB signaling pathway.Feb 17, 2019

Pubmed Data : Life Sci. 2019 Feb 18. Epub 2019 Feb 18. PMID: 30790609
Article Published Date : Feb 17, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps sinensis
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Crocin at a dose of 60 mg/kg for six weeks could be effective in preventing nitrosative stress in hemiparkinsonian rats.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Malays J Med Sci. 2016 Nov ;23(6):35-43. Epub 2016 Dec 7. PMID: 28090177
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Crocin inhibits beta amyloid induced apoptosis, which is possibly associated with its antioxidant properties.Nov 30, 2015

Pubmed Data : Pharmacol Biochem Behav. 2015 Dec ;139(Pt A):47-58. Epub 2015 Oct 17. PMID: 26484504
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Crocin reverses depression-like behaviour in Parkinson disease.Jun 02, 2020

Pubmed Data : Mol Neurobiol. 2020 Jun 3. Epub 2020 Jun 3. PMID: 32495180
Article Published Date : Jun 02, 2020
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Depression, Parkinson's Disease
Pharmacological Actions : Antidepressive Agents
[+]

Crocin showed promising neuroprotective effects in rotenone-induced Parkinson's disease.Dec 03, 2019

Pubmed Data : Neuropharmacology. 2019 Dec 4:107900. Epub 2019 Dec 4. PMID: 31811872
Article Published Date : Dec 03, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Parkinson's Disease
Pharmacological Actions : MicroRNA modulator, Neuroprotective Agents
Problem Substances : Rotenone
[+]

Crocus sativus can be used as a neuroprotective product for neurodegenerative disorders.Dec 16, 2018

Pubmed Data : Acta Histochem. 2018 Dec 17. Epub 2018 Dec 17. PMID: 30573341
Article Published Date : Dec 16, 2018
Study Type : Animal Study
Additional Links
Substances : Saffron
Diseases : Lead Poisoning, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Lead
[+]

Curcumin and naringenin exhibit neuroprotective properties in an animal model of Parkinson's disease.Oct 01, 2005

Pubmed Data : Free Radic Res. 2005 Oct;39(10):1119-25. PMID: 16298737
Article Published Date : Oct 01, 2005
Study Type : Animal Study
Additional Links
Substances : Curcumin, Naringenin
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Curcumin and piperine afforded a better neuroprotective effect compared to each of them alone.Nov 15, 2016

Pubmed Data : Inflammopharmacology. 2016 Nov 16. Epub 2016 Nov 16. PMID: 27853890
Article Published Date : Nov 15, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin, Piperine
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Brain Inflammation, CURCUMIN, Interleukin-1 beta downregulation, Natural Substance Synergy, Parkinson's disease, Piperine
[+]

Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease through suppressing mitochondria dysfunction.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Neurodegener. 2012 ;1(1):16. Epub 2012 Aug 20. PMID: 23210631
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin may be effective in preventing or slowing the progression of Parkinson's Disease.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol Pathol. 2015 Oct ;28(4):197-206. Epub 2015 Jul 27. PMID: 26538809
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo, indicating its value for Parkinson disease. Mar 01, 2008

Pubmed Data : Free Radic Biol Med. 2008 Mar 1;44(5):907-17. Epub 2007 Dec 4. PMID: 18166164
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antineoplastic Agents, Glutathione Upregulation , Neuroprotective Agents
[+]

Curcumin treatment improves motor behavior in α-synuclein transgenic mice.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(6):e0128510. Epub 2015 Jun 2. PMID: 26035833
Article Published Date : Dec 31, 2014
Study Type : Transgenic Animal Study
Additional Links
Substances : Curcumin
Diseases : Alzheimer's Disease, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin was able to significantly ameliorate ROT induced dopaminergic neuronal oxidative damage in the SNpc of rats.Dec 07, 2015

Pubmed Data : Mol Med Rep. 2015 Dec 8. Epub 2015 Dec 8. PMID: 26648392
Article Published Date : Dec 07, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain: Oxidative Stress, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Daidzein exhibits neuroprotective effects against neurotoxins induced toxicity in human neuroblastoma SH-SY5Y cells.Aug 04, 2020

Pubmed Data : Plant Foods Hum Nutr. 2020 Aug 5. Epub 2020 Aug 5. PMID: 32761299
Article Published Date : Aug 04, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Daidzein
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Demethoxycurcumin abrogates rotenone-induced dopamine depletion and motor deficits.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2018 Jan-Mar;14(53):9-16. Epub 2018 Feb 20. PMID: 29576695
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Demethoxycurcumin
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Demethoxycurcumin ameliorates rotenone-induced toxicity.Dec 31, 2018

Pubmed Data : Front Biosci (Elite Ed). 2019 01 1 ;11:1-11. Epub 2019 Jan 1. PMID: 30468633
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Demethoxycurcumin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Rotenone
[+]

Dietary supplementation of walnut attenuated MPTP-induced impairment in a mouse model of Parkinson's disease.May 05, 2015

Pubmed Data : Neurochem Res. 2015 May 6. Epub 2015 May 6. PMID: 25944473
Article Published Date : May 05, 2015
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Neurodegenerative Diseases, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antiparkinson Agents, Enzyme Activators, Neuroprotective Agents
Additional Keywords : Dietary Modification
[+]

Diosgenin attenuates lipopolysaccharide-induced Parkinson's disease.Dec 31, 2017

Pubmed Data : J Alzheimers Dis. 2018 ;64(3):943-955. PMID: 29966203
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Lipopolysaccharide-Induced Toxicity, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Docosahexaenoic acid protects motor function and increases dopamine synthesis.Jan 26, 2020

Pubmed Data : Neuropharmacology. 2020 Jan 27:107976. Epub 2020 Jan 27. PMID: 32001239
Article Published Date : Jan 26, 2020
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Echinacoside protects dopaminergic neurons.Aug 22, 2020

Pubmed Data : Brain Res Bull. 2020 Aug 23 ;164:55-64. Epub 2020 Aug 23. PMID: 32846198
Article Published Date : Aug 22, 2020
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Effects of Boswellia serrata resin extract on motor dysfunction and brain oxidative stress in an experimental model of Parkinson's disease.Apr 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2019 May-Jun;9(3):281-290. PMID: 31143695
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Effects of grape polyphenols on the Life span and neuroinflammatory alterations related to neurodegenerative disease-like disturbances.Nov 15, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Nov 16 ;25(22). Epub 2020 Nov 16. PMID: 33207644
Article Published Date : Nov 15, 2020
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract, Polyphenols
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Electroacupuncture at GV16 and LR3 can improve Parkinson's disease behavioural changes.Dec 24, 2019

Pubmed Data : Zhen Ci Yan Jiu. 2019 Dec 25 ;44(12):873-7. PMID: 31867905
Article Published Date : Dec 24, 2019
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Neuroprotective Agents
[+]

Electroacupuncture may represent an effective adjuvant therapy for motor deficits in patients with Parkinson's disease.Oct 22, 2019

Pubmed Data : J Gerontol A Biol Sci Med Sci. 2019 Oct 23. Epub 2019 Oct 23. PMID: 31644786
Article Published Date : Oct 22, 2019
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents
[+]

Electroacupuncture treatment reduces motor symptoms of Parkinson's disease and dopaminergic neurodegeneration in rodent models.Aug 23, 2017

Pubmed Data : Int J Mol Sci. 2017 Aug 24 ;18(9). Epub 2017 Aug 24. PMID: 28837077
Article Published Date : Aug 23, 2017
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Neuroprotective Agents
[+]

Enhanced oral bioavailability and neuroprotective effect of fisetin through its SNEDDS against rotenone-induced Parkinson's disease.Sep 30, 2020

Pubmed Data : Food Chem Toxicol. 2020 Oct ;144:111590. Epub 2020 Jul 23. PMID: 32710995
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Epigallocatechin gallate has a neurorescue effect in a mouse model of parkinson disease.Aug 22, 2017

Pubmed Data : J Nutr. 2017 Aug 23. Epub 2017 Aug 23. PMID: 28835392
Article Published Date : Aug 22, 2017
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Eplingiella fruticosa leaf essential oil complexed with β-cyclodextrin produces a superior neuroprotective and behavioral profile in Parkinson's disease.Nov 23, 2018

Pubmed Data : Food Chem Toxicol. 2018 Nov 24 ;124:17-29. Epub 2018 Nov 24. PMID: 30481574
Article Published Date : Nov 23, 2018
Study Type : Animal Study
Additional Links
Substances : Essential Oils: Unspecified
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Essential Oils
[+]

Ethanol extract from Gynostemma pentaphyllum ameliorates dopaminergic neuronal cell death in transgenic mice.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2020 Feb ;15(2):361-368. PMID: 31552910
Article Published Date : Jan 31, 2020
Study Type : Transgenic Animal Study
Additional Links
Substances : Gynostemma
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Extracts of Peganum harmala could prevent symptoms and reduced oxidative stress markers in rats with Parkinson’s disease.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2016 ;15(1):275-81. PMID: 27610168
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Syrian rue
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Antioxidants, Brain: Oxidative Stress, Neuroprotective Agents, Parkinson's disease, Plant Extracts, Syrian rue
[+]

Fisetin may improve the mitochondrial enzyme activity, thereby preventing the pathogenesis of Parkinson's disease.Jan 28, 2020

Pubmed Data : J Diet Suppl. 2020 Jan 29:1-15. Epub 2020 Jan 29. PMID: 31992104
Article Published Date : Jan 28, 2020
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Cognitive Decline/Dysfunction, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Rotenone
[+]

Fisetin may slow or prevent neurodegneration and can be utilised as neuroprotective agent against Alzheimer's and Parkinson's disease.Aug 07, 2015

Pubmed Data : J Nutr Biochem. 2015 Aug 8. Epub 2015 Aug 8. PMID: 26411262
Article Published Date : Aug 07, 2015
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Aluminum Toxicity , Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Problem Substances : Aluminum Chloride
Adverse Pharmacological Actions : Neurotoxic
[+]

Fucoidan-rich substances in E. cava could be a potential material for improving cognitive function.Oct 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Oct 17 ;17(10). Epub 2019 Oct 17. PMID: 31627432
Article Published Date : Oct 16, 2019
Study Type : Animal Study
Additional Links
Substances : Fucoidan, Seaweed: Brown
Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

fucoxanthin is a potential D3/D4 agonist for the management of neurodegenerative diseases.Jul 15, 2019

Pubmed Data : Chem Biol Interact. 2019 Jul 16 ;310:108757. Epub 2019 Jul 16. PMID: 31323226
Article Published Date : Jul 15, 2019
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Galangin has a role in protecting dopaminergic neurons by inhibiting microglial activation.Dec 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Dec 21 ;19(1). Epub 2017 Dec 21. PMID: 29267220
Article Published Date : Dec 20, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Lipopolysaccharide-Induced Toxicity, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gastrodin could be of importance for the treatment of Parkinson's disease.Aug 31, 2014

Pubmed Data : Neurochem Int. 2014 Sep ;75:79-88. Epub 2014 Jun 14. PMID: 24932697
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model.Feb 14, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2012 Feb 15 ;7(5):325-31. PMID: 25774170
Article Published Date : Feb 14, 2012
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Gastrodin prevents motor deficits and oxidative stress in model of Parkinson's diseaseOct 01, 2014

Pubmed Data : Life Sci. 2014 Oct 2 ;114(2):77-85. Epub 2014 Aug 14. PMID: 25132361
Article Published Date : Oct 01, 2014
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

Gastrodin protects apoptotic dopaminergic neurons in a toxin-induced Parkinson's disease model.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:514095. Epub 2013 Mar 3. PMID: 23533492
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Gastrodin protects dopaminergic neurons via insulin-like pathway in a Parkinson's disease model.Jun 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Neurosci. 2019 Jun 17 ;20(1):31. Epub 2019 Jun 17. PMID: 31208386
Article Published Date : Jun 16, 2019
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Geraniol is potent in reducing the Parkinson's disease symptoms in transgenic Drosophila model of Parkinson's disease.Mar 31, 2016

Pubmed Data : Environ Toxicol Pharmacol. 2016 Apr ;43:225-31. Epub 2016 Mar 22. PMID: 27026137
Article Published Date : Mar 31, 2016
Study Type : Insect Study
Additional Links
Substances : Geraniol
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Ginseng could be a promising treatment in Parkinson's disease.Dec 31, 2018

Pubmed Data : Curr Pharm Biotechnol. 2019 ;20(7):588-594. PMID: 31198107
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Ginsenoside Rb1 may serve as a potential candidate for the treatment of Parkinson's disease.Jul 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2019 Jul 17 ;11(14):5008-5034. PMID: 31314744
Article Published Date : Jul 16, 2019
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Ginsenoside Rb1 protects dopaminergic neurons from inflammatory injury induced by intranigral lipopolysaccharide injection.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2019 Oct ;14(10):1814-1822. PMID: 31169200
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Gold nanoparticles synthesized using Paeonia mountan alleviates the neuroinflammation and improves the motor coordination in Parkinson induced mice.Oct 15, 2019

Pubmed Data : J Photochem Photobiol B. 2019 Oct 16 ;200:111635. Epub 2019 Oct 16. PMID: 31671372
Article Published Date : Oct 15, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gold (nanoparticles), Peony
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Grape seed and skin extract acts at multiple levels to protect dopamine neurons from degeneration in a model of Parkinson's disease.May 24, 2019

Pubmed Data : Nutr Neurosci. 2019 May 25:1-15. Epub 2019 May 25. PMID: 31131731
Article Published Date : May 24, 2019
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Green tea extracts reversed the striatal oxidative stress and immunohistochemistry alterations in rats.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:161092. Epub 2015 Jun 18. PMID: 26167188
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Catechin , EGCG (Epigallocatechin gallate), Green Tea
Diseases : Neurodegenerative Diseases, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Gut bacteria regulate movement disorders in mice and suggest that alterations in the human microbiome represent a risk factor for PD.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell. 2016 Dec 1 ;167(6):1469-1480.e12. PMID: 27912057
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Dysbiosis, Parkinson's Disease
Additional Keywords : Microbiota, Risk Factors
[+]

Gypenosides attenuate the development of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rat model of Parkinson's disease.Apr 20, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Neurosci. 2015 Apr 21 ;16:23. Epub 2015 Apr 21. PMID: 25896846
Article Published Date : Apr 20, 2015
Study Type : Animal Study
Additional Links
Substances : Gynostemma
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Gypenosides may serve as an adjuvant therapeutic agent for memory deficits in patients with Parkinson's disease receiving L-DOPA.Sep 05, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Sep 6 ;17(1):449. Epub 2017 Sep 6. PMID: 28877690
Article Published Date : Sep 05, 2017
Study Type : Animal Study
Additional Links
Substances : Gynostemma
Diseases : Memory Disorders, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Hericium erinaceus may provide neuroprotective candidates for treating or preventing neurodegenerative diseases.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 Nov 1 ;17(11). Epub 2016 Nov 1. PMID: 27809277
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease, Dementia, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Dose Response
[+]

Hesperidin ameliorates anxiety-depressive-like behaviour.Jun 30, 2020

Pubmed Data : Mol Neurobiol. 2020 Jul ;57(7):3027-3041. Epub 2020 May 26. PMID: 32458386
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Depression, Parkinson's Disease
Pharmacological Actions : Antidepressive Agents
[+]

Hesperidin attenuates iron-induced oxidative damage and dopamine depletion in a model of Parkinson's disease.Jan 04, 2018

Pubmed Data : Chem Biol Interact. 2018 Jan 5 ;279:177-186. Epub 2017 Dec 2. PMID: 29191452
Article Published Date : Jan 04, 2018
Study Type : Insect Study
Additional Links
Substances : Hesperidin
Diseases : Iron Overload, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

High intake of folic acid or complex of B vitamins provides anti-Parkinsonism effect.Jul 31, 2012

Pubmed Data : Behav Brain Res. 2012 Aug 1 ;233(2):375-81. Epub 2012 May 17. PMID: 22610053
Article Published Date : Jul 31, 2012
Study Type : Animal Study
Additional Links
Substances : B-complex, Folic Acid
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Increased dopaminergic degeneration and complications with chronic aspartame consumption and more injury in male groups.Nov 01, 2017

Pubmed Data : Arch Physiol Biochem. 2017 Nov 2:1-8. Epub 2017 Nov 2. PMID: 29096532
Article Published Date : Nov 01, 2017
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Problem Substances : Aspartame
[+]

Insight into the molecular mechanism underlying the inhibition of α-synuclein aggregation by hydroxytyrosol.Nov 18, 2019

Pubmed Data : Biochem Pharmacol. 2019 Nov 19:113722. Epub 2019 Nov 19. PMID: 31756328
Article Published Date : Nov 18, 2019
Study Type : Animal Study
Additional Links
Substances : Hydroxytyrosol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Intestinal infection triggers Parkinson's disease-like symptoms in mice.Dec 31, 2018

Pubmed Data : Nature. 2019 07 ;571(7766):565-569. Epub 2019 Jul 17. PMID: 31316206
Article Published Date : Dec 31, 2018
Study Type : Transgenic Animal Study
Additional Links
Diseases : Enterobacteriaceae Infections, Parkinson's Disease
Additional Keywords : Gut-brain Axis, Risk Factors
[+]

Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson's disease.Jan 10, 2018

Pubmed Data : Mol Genet Metab. 2018 11 ;125(3):305-313. Epub 2018 Aug 10. PMID: 30146452
Article Published Date : Jan 10, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Korean Red Ginseng protects dopaminergic neurons in the ST by ameliorating MPTP-induced impairments in the animal model for PD.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(10):e0164906. Epub 2016 Oct 27. PMID: 27788166
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Lactobacillus plantarum PS128 alleviates neurodegenerative progression.Jul 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain Behav Immun. 2020 Jul 30. Epub 2020 Jul 30. PMID: 32739365
Article Published Date : Jul 29, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Long-term voluntary physical exercise exerts neuroprotective effects and motor disturbance alleviation in a rat model of Parkinson's disease.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Neurol. 2019 ;2019:4829572. Epub 2019 Dec 5. PMID: 31885725
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Exercise
Pharmacological Actions : Neuroprotective Agents
[+]

Lupeol inhibits LPS-induced neuroinflammation in cerebellar cultures and induces neuroprotection.Apr 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 May ;70:302-312. Epub 2019 Mar 7. PMID: 30852286
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Lupeol
Diseases : Alzheimer's Disease, Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

M. nigra fruit juice is effective to attenuate levodopa-induced dyskinesia in an MPTP-induced Parkinson mice model.Dec 31, 2017

Pubmed Data : J Exp Pharmacol. 2018 ;10:29-35. Epub 2018 Jul 4. PMID: 30013404
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Blackberry
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

MECHANISMS UNDERLYING THE NEUROTOXICITY INDUCED BY GLYPHOSATE-BASED HERBICIDE IN IMMATURE RAT HIPPOCAMPUS: INVOLVEMENT OF GLUTAMATE EXCITOTOXICITY.Mar 13, 2014

Pubmed Data : Toxicology. 2014 Mar 14. Epub 2014 Mar 14. PMID: 24636977
Article Published Date : Mar 13, 2014
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation , Neurotoxicity, Parkinson's Disease, Parkinsonism
Problem Substances : Glyphosate formulations, Roundup (herbicide)
Adverse Pharmacological Actions : Excitotoxic, Neurotoxic
[+]

Melatonin is a promising candidate for effective future therapeutic strategies for Parkinson's disease.Dec 31, 2017

Pubmed Data : J Environ Pathol Toxicol Oncol. 2018 ;37(2):139-150. PMID: 30055549
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Melatonin or knockdown of CDK5 reduced MPTP-induced SNCA/α-synuclein aggregation in mice, which is widely thought to trigger the pathogenesis of PD.Aug 19, 2015

Pubmed Data : Autophagy. 2015 Aug 20:0. Epub 2015 Aug 20. PMID: 26292069
Article Published Date : Aug 19, 2015
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Parkinson's Disease
Pharmacological Actions : Autophagy Inhibitors, Neuroprotective Agents
[+]

Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(9):e108034. Epub 2014 Sep 24. PMID: 25251220
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Alzheimer's Disease, Brain Injury: Traumatic, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Risk Reduction
[+]

Morinda citrifolia can be used to alleviate skeletal muscle damage induced by Parkinsonism.Dec 22, 2015

Pubmed Data : Food Funct. 2015 Dec 23. Epub 2015 Dec 23. PMID: 26697948
Article Published Date : Dec 22, 2015
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Mucuna pruriens can be an effective treatment for neurodegenerative diseases.Dec 31, 2013

Pubmed Data : Neurochem Int. 2014 Jan ;65:1-13. Epub 2013 Dec 11. PMID: 24333323
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Mucuna pruriens demonstrates antiparkinsonian activity superior to L-Dopa in a rodent model of Parkinson's disease. Feb 01, 2009

Pubmed Data : Neurotox Res. 2009 Feb;15(2):111-22. Epub 2009 Feb 20. PMID: 19384573
Article Published Date : Feb 01, 2009
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Additional Keywords : Natural Substances Versus Drugs
[+]

Mucuna pruriens efficacy in treating Parkinson's disease may be independent of its levodopa content.Feb 01, 2004

Pubmed Data : Phytother Res. 2004 Feb;18(2):97-101. PMID: 15022157
Article Published Date : Feb 01, 2004
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens is superior to levodopa as an antiparkinson and neurorestorative agent.Sep 01, 2004

Pubmed Data : Phytother Res. 2004 Sep;18(9):706-12. PMID: 15478206
Article Published Date : Sep 01, 2004
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens protects against MPTP intoxicated neuroinflammation in parkinson's disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Aging Neurosci. 2017 ;9:421. Epub 2017 Dec 19. PMID: 29311905
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Dopa bean
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Mucuna pruriens protects or prevents the progression of Parkinson's disease.Jun 18, 2017

Pubmed Data : J Chem Neuroanat. 2017 Jun 19 ;85:27-35. Epub 2017 Jun 19. PMID: 28642128
Article Published Date : Jun 18, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Mucuna pruriens reduces inducible nitric oxide synthase expression in Parkinsonian mice model.Feb 28, 2017

Pubmed Data : J Chem Neuroanat. 2017 Mar ;80:1-10. Epub 2016 Dec 2. PMID: 27919828
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Mucuna pruriens seed extract treatment significantly reduced the Paraquat induced neurotoxicity.May 31, 2013

Pubmed Data : Neurochem Int. 2013 Jun ;62(8):1039-47. Epub 2013 Apr 3. PMID: 23562769
Article Published Date : May 31, 2013
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Paraquat
[+]

Multitarget effects of Korean red ginseng in animal model of Parkinson's diseaseJun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2018 Jul ;42(3):379-388. Epub 2018 Jan 31. PMID: 29983619
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Nanoparticles mediating the sustained puerarin release facilitate improved brain delivery to treat parkinson's disease.Dec 03, 2019

Pubmed Data : ACS Appl Mater Interfaces. 2019 Dec 4 ;11(48):45276-45289. Epub 2019 Oct 29. PMID: 31638771
Article Published Date : Dec 03, 2019
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Naringenin decreases α-synuclein expression and neuroinflammation in Parkinson's disease model.Feb 08, 2018

Pubmed Data : Neurotox Res. 2018 Feb 9. Epub 2018 Feb 9. PMID: 29427283
Article Published Date : Feb 08, 2018
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Brain Inflammation, Naringenin, Parkinson's disease
[+]

Naringenin may act as a potential target in the management of Parkinson's disease.Nov 14, 2018

Pubmed Data : Int J Neurosci. 2018 Nov 15:1-7. Epub 2018 Nov 15. PMID: 30433834
Article Published Date : Nov 14, 2018
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Naringin could be an alternative option in the management of Parkinson's disease.Jan 07, 2020

Pubmed Data : Neuromolecular Med. 2020 Jan 8. Epub 2020 Jan 8. PMID: 31916219
Article Published Date : Jan 07, 2020
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Rotenone
[+]

Neuroprotection by paeoniflorin in the MPTP mouse model of Parkinson's disease.Dec 31, 2016

Pubmed Data : Neuropharmacology. 2017 04 ;116:412-420. Epub 2017 Jan 16. PMID: 28093210
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Parkinson's Disease
Pharmacological Actions : Bcl-2 protein down-regulation, Neuroprotective Agents
[+]

Neuroprotective activities of palmitoylethanolamide in an animal model of Parkinson's disease.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(8):e41880. Epub 2012 Aug 17. PMID: 22912680
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective and neurorescue effect of black tea extract in 6-hydroxydopamine-lesioned rat model of Parkinson's disease.May 01, 2006

Pubmed Data : Neurobiol Dis. 2006 May ;22(2):421-34. Epub 2006 Feb 9. PMID: 16480889
Article Published Date : May 01, 2006
Study Type : Animal Study
Additional Links
Substances : Black Tea, Tea
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Neuroprotective effect of a standardized extract of Centella asiatica ECa233 in rotenone-induced parkinsonism.May 14, 2018

Pubmed Data : Phytomedicine. 2018 May 15 ;44:65-73. Epub 2018 Apr 16. PMID: 29895494
Article Published Date : May 14, 2018
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation
Problem Substances : Rotenone
[+]

Neuroprotective effect of fucoidan from Turbinaria decurrens in MPTP intoxicated Parkinsonic mice.Apr 30, 2016

Pubmed Data : Int J Biol Macromol. 2016 May ;86:425-33. Epub 2016 Jan 29. PMID: 26828289
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Neuroprotective effect of gold nanoparticles composites in Parkinson's disease model.Feb 20, 2018

Pubmed Data : Nanomedicine. 2018 Feb 21. Epub 2018 Feb 21. PMID: 29474924
Article Published Date : Feb 20, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gold (nanoparticles)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective effect of quercetin in combination with piperine against rotenone-and iron supplement-induced Parkinson's disease.Oct 24, 2019

Pubmed Data : Neurotox Res. 2019 Oct 25. Epub 2019 Oct 25. PMID: 31654381
Article Published Date : Oct 24, 2019
Study Type : Animal Study
Additional Links
Substances : Piperine, Quercetin
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Neuroprotective effects of Astilbin on MPTP-induced Parkinson's disease.Dec 31, 2018

Pubmed Data : Int Immunopharmacol. 2019 Jan ;66:19-27. Epub 2018 Nov 9. PMID: 30419450
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective effects of Bacopa monnieri in Parkinson's disease model.Dec 12, 2019

Pubmed Data : Metab Brain Dis. 2019 Dec 13. Epub 2019 Dec 13. PMID: 31834548
Article Published Date : Dec 12, 2019
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Neuroprotective effects of germinated brown rice in rotenone-induced Parkinson's-like disease.Aug 31, 2016

Pubmed Data : Neuromolecular Med. 2016 Sep ;18(3):334-46. Epub 2016 Jul 18. PMID: 27430236
Article Published Date : Aug 31, 2016
Study Type : Animal Study
Additional Links
Substances : Brown Rice: Pre-Germinated
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective effects of pomegranate juice against Parkinson's disease.Dec 26, 2019

Pubmed Data : Int J Mol Sci. 2019 Dec 27 ;21(1). Epub 2019 Dec 27. PMID: 31892167
Article Published Date : Dec 26, 2019
Study Type : Animal Study
Additional Links
Substances : Pomegranate, Urolithin A
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Neuroprotective mechanisms of S-allyl-L-cysteine in neurological disease.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1565-1569. Epub 2019 Dec 27. PMID: 32010340
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective nechanisms of three natural antioxidants on a rat model of Parkinson's disease.Jan 05, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Jan 6 ;9(1). Epub 2020 Jan 6. PMID: 31935828
Article Published Date : Jan 05, 2020
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid, Ellagic Acid
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Nobiletin rescues motor and cognitive dysfunction in a MPTP-induced Parkinson model mice, in part by enhancing dopamine release.Feb 13, 2014

Pubmed Data : Neuroscience. 2014 Feb 14 ;259:126-41. Epub 2013 Dec 4. PMID: 24316474
Article Published Date : Feb 13, 2014
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Cognitive Decline/Dysfunction, Parkinson's Disease, Parkinsonian Disorders
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Octacosanol might be considered as a candidate agent for clinical application in treating Parkinson's disease.May 14, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2012 May 15 ;7(14):1080-7. PMID: 25722698
Article Published Date : May 14, 2012
Study Type : Animal Study
Additional Links
Substances : Octacosanol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Olive leaves extract might be useful for preventing the death of dopaminergic neurons in patients with Parkinson's disease.Jan 31, 2018

Pubmed Data : Metab Brain Dis. 2018 Feb ;33(1):79-88. Epub 2017 Oct 16. PMID: 29039078
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Olive leaf extract
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Oral delivery of puerarin nanocrystals to improve brain accumulation and anti-parkinsonian efficacy.Mar 31, 2019

Pubmed Data : Mol Pharm. 2019 Apr 1 ;16(4):1444-1455. Epub 2019 Mar 6. PMID: 30811206
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

P. cincinnata ethanolic extract exerted a neuroprotective effect in a progressive model of Parkinson's disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:8429290. Epub 2017 Aug 1. PMID: 28835767
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

P. incarnata flowers may be employed in treatment of dementia and parkinsonism.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anc Sci Life. 2017 Apr-Jun;36(4):200-206. PMID: 29269972
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Alzheimer's Disease, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

P. oleracea can be considered as potential strategy for treating Parkinson's disease. Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : An Acad Bras Cienc. 2016 Sep ;88(3):1439-50. Epub 2016 Aug 4. PMID: 27508995
Article Published Date : Aug 31, 2016
Study Type : Animal Study
Additional Links
Substances : Purslane
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Paeoniflorin might be a valuable neuroprotective agent for the treatment of Parkinson's disease.May 31, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2006 Jun ;148(3):314-25. PMID: 16582933
Article Published Date : May 31, 2006
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Inflammation, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Palmitoylethanolamide prevents Parkinsonian phenotypes in aged mice.Mar 18, 2018

Pubmed Data : Mol Neurobiol. 2018 Mar 19. Epub 2018 Mar 19. PMID: 29552727
Article Published Date : Mar 18, 2018
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Neuroprotective Agents, Palmitoylethanolamide, Parkinson's disease
[+]

Palmitoylethanolamide protects mice against 6-OHDA-induced neurotoxicity and endoplasmic reticulum stressOct 31, 2016

Pubmed Data : Pharmacol Res. 2016 Nov ;113(Pt A):276-289. Epub 2016 Sep 8. PMID: 27616549
Article Published Date : Oct 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Neurodegenerative Diseases, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Phloretin attenuates behavior deficits and neuroinflammatory response in MPTP induced Parkinson's disease in mice.Jun 24, 2019

Pubmed Data : Life Sci. 2019 Jun 25:116600. Epub 2019 Jun 25. PMID: 31251998
Article Published Date : Jun 24, 2019
Study Type : Animal Study
Additional Links
Substances : Phloretin
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Photobiomodulation has potential as therapeutic tool for reducing vascular dysfunction in neurological conditions.Jan 03, 2019

Pubmed Data : Biomolecules. 2019 10 4 ;9(10). Epub 2019 Oct 4. PMID: 31590236
Article Published Date : Jan 03, 2019
Study Type : Animal Study
Additional Links
Diseases : Neurologic Disorders, Parkinson's Disease
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Neuroprotective Agents
[+]

Piper longum possesses neuroprotective effects and has ameliorative properties in dopaminergic neurons.Sep 30, 2015

Pubmed Data : Pharm Biol. 2015 Oct ;53(10):1516-24. Epub 2015 Apr 10. PMID: 25857256
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Long Pepper
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

Piperine in combination with quercetin halt 6-OHDA induced neurodegeneration.Oct 18, 2017

Pubmed Data : Neurosci Res. 2017 Oct 19. Epub 2017 Oct 19. PMID: 29056550
Article Published Date : Oct 18, 2017
Study Type : Animal Study
Additional Links
Substances : Piperine, Quercetin
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
[+]

Piperlongumine restores the balance of autophagy and apoptosis in rotenone-induced Parkinson disease models.Feb 12, 2018

Pubmed Data : Autophagy. 2018 Feb 13:1-17. Epub 2018 Feb 13. PMID: 29433359
Article Published Date : Feb 12, 2018
Study Type : Animal Study
Additional Links
Substances : Piperlongumine
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Plantain husk (psyllium) improves the bioavailability of levodopa (with carbidopa).Aug 15, 2008

Pubmed Data : J Neurol Sci. 2008 Aug 15;271(1-2):15-20. Epub 2008 May 12.PMID:18474374
Article Published Date : Aug 15, 2008
Study Type : Animal Study
Additional Links
Substances : Psyllium
Diseases : Parkinson's Disease
[+]

Polyphenols from Toona sinensis seeds alleviate neuroinflammation in rats with Parkinson's disease.Aug 31, 2019

Pubmed Data : Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2019 Sep ;35(9):794-799. PMID: 31750820
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Polyphenols, Toona sinensis
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Polyphenols from Toona sinensiss seeds alleviate neuroinflammation induced by 6-hydroxydopamine.Jun 16, 2020

Pubmed Data : Neurochem Res. 2020 Jun 17. Epub 2020 Jun 17. PMID: 32556929
Article Published Date : Jun 16, 2020
Study Type : Animal Study
Additional Links
Substances : Polyphenols, Toona sinensis
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Present findings show that pistachio possesses neuroprotective effects and improves memory and motor deficits.Jun 10, 2020

Pubmed Data : Metab Brain Dis. 2020 Jun 11. Epub 2020 Jun 11. PMID: 32529399
Article Published Date : Jun 10, 2020
Study Type : Animal Study
Additional Links
Substances : Pistachio nut
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Rotenone
[+]

Pretreatment with spirulina showed an anti-parkinsonism effect on behavior and anti-oxidant parameters on 6-OHDA induced dopaminergic damage rats.Dec 31, 2014

Pubmed Data : BMC Complement Altern Med. 2015 ;15:296. Epub 2015 Aug 25. PMID: 26306668
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Probiotics could ameliorate neurodegeneration at least partially by increasing butyrate level.Jun 30, 2019

Pubmed Data : J Nutr Biochem. 2019 Jul ;69:73-86. Epub 2019 Apr 6. PMID: 31063918
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Probiotics
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Prophylactic neuroprotective propensity of crocin against rotenone induced neurotoxicity.Jun 17, 2019

Pubmed Data : Metab Brain Dis. 2019 Jun 18. Epub 2019 Jun 18. PMID: 31214956
Article Published Date : Jun 17, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Rotenone
[+]

Protective and therapeutic activity of honokiol in reversing motor deficits and neuronal degeneration in a model of Parkinson's disease.Jul 31, 2018

Pubmed Data : Pharmacol Rep. 2018 Aug ;70(4):668-676. Epub 2018 Jan 12. PMID: 29909247
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Honokiol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Protective effect of alpha mangostin on rotenone induced toxicity in rat model of Parkinson's disease.Jan 17, 2020

Pubmed Data : Neurosci Lett. 2020 Jan 18 ;716:134652. Epub 2019 Nov 25. PMID: 31778768
Article Published Date : Jan 17, 2020
Study Type : Animal Study
Additional Links
Substances : Mangosteen
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Rotenone
[+]

Protective effect of Indole-3-carbinol, an NF-κB inhibitor in experimental paradigm of Parkinson's disease.Oct 31, 2020

Pubmed Data : Brain Behav Immun. 2020 Nov ;90:108-137. Epub 2020 Aug 12. PMID: 32800927
Article Published Date : Oct 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in the MPTP-induced mouse model of Parkinson's disease.Nov 14, 2015

Pubmed Data : Eur J Pharmacol. 2015 Nov 15 ;767:175-82. Epub 2015 Oct 20. PMID: 26477638
Article Published Date : Nov 14, 2015
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Puerarin attenuates neuronal degeneration in the substantia nigra of 6-OHDA-lesioned rats.Jul 25, 2013

Pubmed Data : Brain Res. 2013 Jul 26 ;1523:1-9. Epub 2013 Jun 5. PMID: 23747813
Article Published Date : Jul 25, 2013
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Brain-derived neurotrophic factor modulator, Neuroprotective Agents, Nrf2 activation
[+]

Puerarin effectively exerts its neuroprotective action against 6-OHDA-induced Parkinsonian.Jun 22, 2013

Pubmed Data : Brain Res. 2013 Jun 23 ;1517:28-35. Epub 2013 Apr 17. PMID: 23603411
Article Published Date : Jun 22, 2013
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents
[+]

Puerarin mediates anti-apoptotic and anti-inflammatory activities and plays a neuroprotective role.Oct 04, 2016

Pubmed Data : Genet Mol Res. 2016 Oct 5 ;15(4). Epub 2016 Oct 5. PMID: 27808353
Article Published Date : Oct 04, 2016
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Puerarin promoted proliferation and differentiation of dopamine-producing cells in Parkinson's models.Sep 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Oct ;106:1236-1242. Epub 2018 Jul 20. PMID: 30119192
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotectionJan 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nat Commun. 2020 02 18 ;11(1):941. Epub 2020 Feb 18. PMID: 32071304
Article Published Date : Jan 17, 2020
Study Type : Animal Study
Additional Links
Substances : Vitamin B-6
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Glutathione Upregulation , Neuroprotective Agents
[+]

Reishi (Ganoderma Lucidum) protects dopaminergic cells in an animal model of Parkinson disease. Jun 01, 2005

Pubmed Data : Di Yi Jun Yi Da Xue Xue Bao. 2005 Jun;25(6):667-71. PMID:15958304
Article Published Date : Jun 01, 2005
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Resveratrol attenuates 6-hydroxydopamine-induced oxidative damage and dopamine depletion in rat model of Parkinson's disease.Apr 30, 2010

Pubmed Data : Brain Res. 2010 Apr 30;1328:139-51. Epub 2010 Feb 16. PMID: 20167206
Article Published Date : Apr 30, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Dopamine Deficiency, Lipid Peroxidation, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Dopaminergic
[+]

Resveratrol can elicit neuroprotective effects on rotenone-induced parkinsonism.May 02, 2017

Pubmed Data : Neuroreport. 2017 May 3. Epub 2017 May 3. PMID: 28471847
Article Published Date : May 02, 2017
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Rotenone
[+]

Resveratrol could be used as a neuroprotective therapeutic agent in Parkinson disease.Jan 18, 2018

Pubmed Data : Anat Rec (Hoboken). 2018 Jan 19. Epub 2018 Jan 19. PMID: 29350822
Article Published Date : Jan 18, 2018
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Resveratrol induces HO-1 expression and prevents dopaminergic cell death.Jan 21, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2014 Jan 22 ;15(1):1625-46. Epub 2014 Jan 22. PMID: 24451142
Article Published Date : Jan 21, 2014
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Heme oxygenase-1 up-regulation, Neuroprotective Agents
[+]

S. chinensis fruit extract is a potential herbal drug candidate for the amelioration and prevention of Parkinson's disease.Jul 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Jul 21 ;11(7). Epub 2019 Jul 21. PMID: 31330885
Article Published Date : Jul 20, 2019
Study Type : Animal Study
Additional Links
Substances : Schisandra
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Saffron may be exploited as a supplementary therapeutic agent in PD and other oxidative stress mediated neurodegenerative conditions.Dec 16, 2015

Pubmed Data : Neurotoxicology. 2015 Dec 17 ;52:230-242. Epub 2015 Dec 17. PMID: 26705857
Article Published Date : Dec 16, 2015
Study Type : Insect Study
Additional Links
Substances : Crocin, Saffron
Diseases : Neurodegenerative Diseases, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Safranal may serve as a potent and promising therapeutic drug for the treatment of Parkinson's disease.Dec 29, 2016

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2016 Dec 30 ;62(14):11-17. Epub 2016 Dec 30. PMID: 28145852
Article Published Date : Dec 29, 2016
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Sesamin may act as an adjuvant phytonutrient for motor and memory deficits in patients with Parkinson's disease receiving l-DOPA.Dec 16, 2016

Pubmed Data : Neuroscience. 2016 Dec 17 ;339:644-654. Epub 2016 Oct 24. PMID: 27789382
Article Published Date : Dec 16, 2016
Study Type : Animal Study
Additional Links
Substances : Sesamin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Silibinin protected dopaminergic neurons in an acute MPTP-induced mouse model of Parkinson's disease.Nov 18, 2015

Pubmed Data : Brain Res. 2015 Nov 19 ;1627:233-42. Epub 2015 Oct 3. PMID: 26434409
Article Published Date : Nov 18, 2015
Study Type : Animal Study
Additional Links
Substances : Silibinin
Diseases : Alzheimer's Disease, Brain Inflammation , Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Sodium butyrate exerts protective effect against Parkinson's disease in mice.Oct 14, 2017

Pubmed Data : J Neurol Sci. 2017 Oct 15 ;381:176-181. Epub 2017 Aug 24. PMID: 28991675
Article Published Date : Oct 14, 2017
Study Type : Animal Study
Additional Links
Substances : Butyrate
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Soy meal may have the potential neuroprotective effect against post-menopausal cognitive deficiency and weight gain.Oct 15, 2009

Pubmed Data : Pak J Biol Sci. 2009 Oct 15;12(20):1338-45. PMID: 20128500
Article Published Date : Oct 15, 2009
Study Type : Animal Study
Additional Links
Substances : Isoflavones, Soy Protein
Diseases : Neurodegenerative Diseases, Parkinson's Disease, Perimenopausal Syndrome, Postmenopausal Disorders: Weight Gain/Obesity
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Ovariectomy-Induced Changes
[+]

Standardized safflower flavonoid extract represents a potential therapeutic herbal treatment for Parkinson's disease.Aug 23, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 Aug 24 ;21(9). Epub 2016 Aug 24. PMID: 27563865
Article Published Date : Aug 23, 2016
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Study on Antrodia camphorata polysaccharide in alleviating the neuroethology of Parkinson's disease.Aug 31, 2019

Pubmed Data : Phytother Res. 2019 Sep ;33(9):2288-2297. Epub 2019 Jul 29. PMID: 31359520
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Antrodia camphorata
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Subchronic honokiol treatment extended the lifespan of these hemiparkinsonian mice.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2018 Dec ;108:254-262. Epub 2018 Sep 14. PMID: 30223096
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Honokiol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Supplementation with nobiletin may protect against the neurodegeneration involved in PD. Mar 31, 2015

Pubmed Data : J Med Food. 2015 Apr ;18(4):409-14. Epub 2014 Oct 17. PMID: 25325362
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Supplementation with ω-3 PUFAs prevents behavioural and neurochemical disturbances induced by 6-OHDA.Nov 23, 2016

Pubmed Data : Basic Clin Pharmacol Toxicol. 2016 Nov 24. Epub 2016 Nov 24. PMID: 27883274
Article Published Date : Nov 23, 2016
Study Type : Animal Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Tangeretin inhibits neurodegeneration and attenuates inflammatory responses and behavioural deficits in induced Parkinson's disease dementia.Jul 31, 2017

Pubmed Data : Inflammopharmacology. 2017 Aug ;25(4):471-484. Epub 2017 Jun 2. PMID: 28577132
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Tangeretin
Diseases : Brain Inflammation , Dementia, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation
[+]

Tanshinone IIA may possess anti-inflammatory and anti-oxidative properties and may have therapeutic value in the treatment of Parkinson's disease.Jan 14, 2015

Pubmed Data : J Neurol Sci. 2015 Jan 15 ;348(1-2):142-52. Epub 2014 Nov 28. PMID: 25491263
Article Published Date : Jan 14, 2015
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Tetrahydrocannabivarin could be used for delaying disease progression in PD and also for ameliorating parkinsonian symptoms.Jul 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2011 Aug ;163(7):1495-506. PMID: 21323909
Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : Cannabinoids
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

THC mediates neuroprotection via PPARγ-dependent restoration of mitochondrial content which may be beneficial for PD treatment.Jun 26, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Jun 27. Epub 2016 Jun 27. PMID: 27366949
Article Published Date : Jun 26, 2016
Study Type : Animal Study
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

The association of palmitoylethanolamide with luteolin decreases neuroinflammation and stimulates autophagy in Parkinson's disease.Dec 31, 2014

Pubmed Data : CNS Neurol Disord Drug Targets. 2015 ;14(10):1350-65. PMID: 26295827
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Luteolin, Palmitoylethanolamide
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : anti-inflammatory, Autophagy Up-regulation, Neuroprotective Agents
[+]

The effect of preventive exercise on the neuroprotection in 6-hydroxydopamine-lesioned rat brain.Nov 30, 2019

Pubmed Data : Appl Physiol Nutr Metab. 2019 Dec ;44(12):1267-1275. Epub 2019 Nov 6. PMID: 31691583
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Exercise
Pharmacological Actions : Neuroprotective Agents
[+]

The findings suggest that B. caapi alone has a mild antiparkinsonian effect.Jan 23, 2018

Pubmed Data : Phytother Res. 2018 Jan 24. Epub 2018 Jan 24. PMID: 29368409
Article Published Date : Jan 23, 2018
Study Type : Animal Study
Additional Links
Substances : Ayahuasca
Diseases : Parkinson's Disease
Additional Keywords : Ayahuasca, Parkinson's disease
[+]

The isothiocyanate isolated from Moringa oleifera shows potent anti-inflammatory activity in the treatment of murine sub-acute Parkinson's disease.May 31, 2016

Pubmed Data : Rejuvenation Res. 2016 Jun 1. Epub 2016 Jun 1. PMID: 27245199
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Isothiocyanate, Moringa oleifera
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The ketogenic diet was neuroprotective and anti-inflammatory against MPTP-neurotoxicity.Sep 30, 2010

Pubmed Data : J Mol Neurosci. 2010 Oct ;42(2):145-53. Epub 2010 Mar 24. PMID: 20333481
Article Published Date : Sep 30, 2010
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Brain: Microglial Activation, Parkinson's Disease
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

The models suggest possible bidirectional communication between the gut and the brain for the genesis of PD-like phenotype and pathology.Mar 08, 2017

Pubmed Data : Nutr Neurosci. 2017 Mar 9:1-12. Epub 2017 Mar 9. PMID: 28276272
Article Published Date : Mar 08, 2017
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Parkinson's Disease
Additional Keywords : Gut-brain Axis
[+]

The oral administration of delta tocotrienol may be useful in the treatment of Parkinson's disease patients.Oct 29, 2015

Pubmed Data : Neurosci Lett. 2015 Oct 30. Epub 2015 Oct 30. PMID: 26523792
Article Published Date : Oct 29, 2015
Study Type : Animal Study
Additional Links
Substances : Tocotrienol: Delta, Vitamin E
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Tamoxifen
[+]

The present study demonstrated that Parkinson's disease induces proteomic changes in the motor cortex, some of which are rescued by EA treatment.Jul 27, 2017

Pubmed Data : Brain Res. 2017 Jul 28. Epub 2017 Jul 28. PMID: 28760440
Article Published Date : Jul 27, 2017
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease
Therapeutic Actions : Electroacupuncture
[+]

The present study showed protective effects of thymol in rotenone-induced neurotoxicity and neurodegeneration.Mar 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Mar 27 ;20(7). Epub 2019 Mar 27. PMID: 30934738
Article Published Date : Mar 26, 2019
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

The present study shows that A. blazei extract act as potential neuroprotective agent in the management of Parkinsonism.Dec 31, 2018

Pubmed Data : Front Biosci (Elite Ed). 2019 01 1 ;11:12-19. Epub 2019 Jan 1. PMID: 30468634
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Agaricus Blazei
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

The results demonstrate that silymarin protects against MPTP-induced changes in autophagy leading to Parkinsonism.Nov 14, 2019

Pubmed Data : J Mol Neurosci. 2019 Nov 15. Epub 2019 Nov 15. PMID: 31732923
Article Published Date : Nov 14, 2019
Study Type : Animal Study
Additional Links
Substances : Silymarin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents

Copyright: designua / 123RF Stock Photo

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Testing a 2,500 Year-Old Hypothesis
Written by John Stuart Reid
If music breathes new life into old blood cells, play on!
Broccoli Can Stimulate Brain Regeneration, New Research Suggests
Written by Sayer Ji, Founder
For decades it was believed that brain regeneration was not possible. But an accumulating body of research now reveals that common foods such as broccoli contain compounds capable of stimulating the repair and renewal of nerve tissue
Red Clover Beats Inflammation and Oxidative Stress
Written by Dr. Diane Fulton
Brain Regeneration: Can Infrared Light Reverse Parkinson’s and Alzheimer’s?
Written by Ali Le Vere, B.S., B.S. - Senior Researcher-GreenMedInfo
Contrary to conventional wisdom, brain regeneration is possible. One promising therapy that promotes neurogenesis and is effective in pre-clinical studies of Alzheimer’s and Parkinson’s is near infrared light therapy, and it may improve other mental illnesses and neurodegenerative disorders including dementia, stroke, ALS, and traumatic brain injury as well
Measles: The New Red Scare
Written by Roman Bystrianyk
Irrational Measles Fear is being used as a Pretext for Infringing on Individual Rights
300+ Evidence-Based Longevity Promoting Natural Substances
Written by GreenMedInfo Research Group
Research has concluded that a healthy diet rich in antioxidants and anti-inflammatory natural substances can increase longevity and improve the aging process
A Natural Approach to Preventing and Overcoming Dementia
Written by Gary Null, PhD
Contrary to mainstream medical belief, safe, natural, and nontoxic treatments can alleviate the symptoms of senile dementia. Research has demonstrated how these remedies can aid in preventing the onset of senile dementia.
Parkinson's Disease: Critical Risk Factors and Treatment Alternatives
Written by GreenMedInfo Research Group
While Parkinson's disease has no known cause or cure, a number of critical risk factors have been identified and advances have been made in alternative treatment options. Ultimately, increasing quality of life for those with Parkinson's disease is the goal
Magnesium Chloride Health Benefits
Written by Dr. Mark Sircus
For purposes of cellular detoxification and tissue purification, the most effective form of magnesium is magnesium chloride, which has a strong excretory effect on toxins and stagnant energies stuck in the tissues of the body, drawing them out through the pores of the skin. Chloride is required to produce a large quantity of gastric acid each day and is also needed to stimulate starch-digesting enzymes
Eating Wheat & Cow's Milk Disrupt DNA Expression & Antioxidant Status
Written by Sayer Ji, Founder
Could two of the Western world's most popular foods - wheat and cow's dairy - be depleting you of your antioxidants and altering your DNA expression in a harmful way?
Highly-Fit Women 90% Less Likely to Develop Dementia Later
Written by GreenMedInfo Research Group
A new long-term study on dementia has highlighted the importance of staying as fit as possible, for as long as possible, to ensure not just a healthy body, but also a healthy mind
What If A Vitamin Could Have Saved Robin Williams?
Written by William Conder
Robin Williams' health history would have made him a perfect candidate for Hoffer's high-dose niacin therapy. But would this therapy been better than the "best" drugs available to Williams?
Vaccines' Dark Inferno: What Is Not on Insert Labels?
Written by Gary Null, PhD and Richard Gale
Do you know what's in a vaccine? Will the active, inert and hidden ingredients in a vaccine make you question if you want vaccines in your body?
Why I Kicked My Keurig to the Curb
Written by Erin Chamerlik, MS, MT(ASCP)
What I discovered in my own Keurig was shocking and sickening and why I am kicking my Keurig to the curb
Outlawed Berries Boost Brain Power and Mood
Written by Margie King, Health Coach
Over a hundred years ago Congress outlawed black currants. Today this forbidden fruit is making a comeback and may help improve your mood and brain power.
AutismOne Joins With Focus Autism For AutismOne/Focus Autism 2015 Conference
Written by GMI Reporter
AutismOne, Focus Autism and a diverse group of speakers will present important, up-to-date research and information on autism through innovative sessions "fighting the good fight to keep you and your family healthy."
May All Your Medicines Be Green
Written by Tracy Kolenchuk
Hippocrates - the father of medicine - said, "Let your food be your medicine, and let your medicine be your food." Medicines are a subset of foods, according to Hippocrates. I like that. What are medicines today? What are foods?
Top Five Health Benefits of Ginsenosides
Written by GreenMedInfo Research Group
Ginsenosides, the main compound in ginseng root, have been well-researched for their immune-boosting, antioxidant and anti-inflammatory benefits. Researchers believe this powerful compound could present an alternative treatment method for a variety of health issues, including neurological disorders, erectile dysfunction and fatigue
Vitamin D Deficiency in Pregnancy Linked to Higher ADHD Risk in Children
Written by GreenMedInfo Research Group
The value of optimal vitamin D levels in the body cannot be emphasized enough, especially among pregnant women. In a Finnish study, the risk of attention deficit hyperactivity disorder (ADHD) was 34% greater in children whose mother suffered from a vitamin D deficiency during pregnancy, compared to those whose mother’s vitamin D status was sufficient in the first and second trimesters
Green Tea May Have Brain Healing Properties
Written by Sayer Ji, Founder
Research reveals that green tea could be a powerful brain healer by stimulating the activity of a nerve growth factor known as BDNF
What's Inside an Ayurvedic Medicine Cabinet?
Written by GMI Reporter
Thanks to the preservation of some sacred texts, we have access to the wisdom of 5000 years of medical science. Find out what healing substances have stood the test of time, and are still some of the safest and most potent medicines available today
Bayer Needs More Than an Aspirin to Cure its Monsanto-Sized Headache
Written by Robert F. Kennedy, Jr.
Bayer is facing a cascade of new Roundup cases and a possible rash of shareholder lawsuits by its own investors alleging that Bayer failed to disclose its true liabilities

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