Parkinson's Disease

Name	AC	CK
Flavonoids	49	101
Cannabidiol	22	64
Coenzyme Q10	13	63
Melatonin	14	63
Curcumin	41	59
Vitamin E	5	54
Vitamin C	11	51
Ginkgo biloba	17	46
Ginsenosides	21	45
Vitamin D	5	42
Mucuna pruriens (aka Velvet Beans)	13	39
Probiotics	9	39
Resveratrol	24	37
Baicalein	10	35
Anthocyanins	6	33
Bee Venom	8	30
Polyphenols	18	23
B-complex	3	22
Cannabis	4	22
Carvacrol	8	22
Pycnogenol (Pine Bark)	3	22
beta-Carotene	2	22
Bacopa	10	21
Vitamin B-12	3	21
5-HTP (5-Hydroxytryptophan)	2	20
EGCG (Epigallocatechin gallate)	15	20
Crocin	11	19
Hydrogen Water	6	19
Naringenin	13	19
Gastrodin	10	18
Hydrogen: Molecular	5	18
Palmitoylethanolamide	5	18
Puerarin	10	18
Alpha-Lipoic Acid	5	17
Thymoquinone	13	17
Berberine	5	16
Ashwagandha	11	15
Catechin	8	15
Omega-3 Fatty Acids	5	15
Safflower	8	15
Astaxanthin	12	14
Vitamin B-6	4	14
Chrysin	8	13
Echinacea	8	13
Fisetin	8	13
Fucoidan	8	13
Ginseng (Korean)	7	13
NAC (N-acetyl-L-cysteine)	3	13
Paeoniflorin	8	13
Cannabinoids	9	12
Lion's Mane (Hericium Erinaceus)	7	12
Quercetin	10	12
Delta-tetrahydrocannabinol (THC)	5	11
Piperine	7	11
Astragaloside	7	10
Black Currant	1	10
Black Tea	6	10
Cholesterol	1	10
Coconut Oil	1	10
Culinary Herbs and Spices	1	10
Fish Oil	1	10
Flavan-3-ols	1	10
Fruit: All	1	10
Gotu Kola	7	10
Grape	1	10
Hesperidin	6	10
Iberogast	1	10
Marjoram	1	10
Olive Oil	1	10
Prebiotics	1	10
SAMe (S-adenosylmethionine)	1	10
Theanine	6	10
Vegetables: All	1	10
Vitamin B-3 (Niacin)	1	10
Beta-Caryophyllene	5	9
Carnosic Acid	6	9
Citrus naringin	7	9
Ellagic Acid	7	9
Lactobacillus plantarum	5	9
Mangiferin	5	9
Peony	5	9
Phloretin	3	9
Cordyceps Militaris	5	8
Green Tea	7	8
Hydroxytyrosol	5	8
Saffron	5	8
Ursolic Acid	5	8
Asiatic Acid	5	7
Caffeic acid phenethyl ester	5	7
DHA (Docosahexaenoic Acid)	4	7
Gynostemma	4	7
Honokiol	5	7
Nobiletin	5	7
Pomegranate	4	7
Rosemaric Acid	5	7
Salvia miltiorrhiza	4	7
Silibinin	4	7
Spirulina	4	7
Thymol	3	7
Urolithin A	4	7
Verbascoside	4	7
6-Shogaol	4	6
Apigenin	4	6
Holy Basil	2	6
Luteolin	4	6
Lycopene	4	6
Mangosteen	4	6
Moringa oleifera	4	6
Mulberry	3	6
Myricetin	5	6
Oleuropein	5	6
Tangeretin	4	6
Tea	4	6
Agaricus Blazei	3	5
Amurensin G	1	5
Chlorogenic Acid	4	5
Cocoa	4	5
Demethoxycurcumin	3	5
Frankincense	3	5
Garcinia kola	3	5
Garlic	3	5
Guduchi	3	5
Isoflavones	3	5
Sesamin	3	5
Sesamol	3	5
Sulforaphane	5	5
Sumac	1	5
Theaflavins	3	5
Vanillin	3	5
Walnut	3	5
Apocynin	2	4
Blueberry	3	4
Carnosine	2	4
Carotenoids	4	4
Celastrol	3	4
Chicoric Acid	2	4
Coffee	3	4
Dopa bean	2	4
Ferulic acid	3	4
Fucoxanthin	3	4
Geraniol	3	4
Ginger	4	4
Gold (nanoparticles)	2	4
Grape Seed Extract	2	4
Icariin	3	4
Indole-3-Carbinol	2	4
Long Pepper	2	4
Nettle	2	4
Paeonol	3	4
Passion Flower	2	4
Punicalagin	3	4
Rosemary	4	4
Rutin	4	4
Seaweed: Brown	2	4
Tanshinone IIA	3	4
Toona sinensis	2	4
Ayahuasca	2	3
Betanin	2	3
Betulinic acid	2	3
Caffeine	2	3
Chaenomeles speciosa	2	3
Chinese Skullcap	2	3
Cinnamaldehyde	1	3
Citicoline	3	3
Coriandrum sativum	2	3
Daidzein	2	3
Dogwood	2	3
Fenugreek	3	3
Fermented Foods and Beverages	2	3
Folic Acid	2	3
Genistein	2	3
Gingerol	3	3
Goji	2	3
Horse Chestnut	2	3
Lactoferrin	3	3
Licorice	2	3
Lutein	2	3
Magnesium	2	3
Melanin: Bacterial	2	3
Multivitamin	1	3
Nigella sativa (aka Black Seed)	3	3
Noni	2	3
Piceatannol	2	3
Pistachio nut	2	3
Reishi Mushroom	2	3
Rosmarinic acid	3	3
Safranal	2	3
Selenium	3	3
Sesame Seeds	2	3
Shikonin	2	3
Spikenard	2	3
St. Johns Wort	2	3
Stilbenes	2	3
Syrian rue	2	3
Acai	1	2
Amla Fruit	2	2
Andrographis	2	2
Antrodia camphorata	1	2
Arctigenin	1	2
Artemisinin	1	2
Beet	1	2
Bifidobacterium Breve	1	2
Biochanin A	1	2
Black Tea Theaflavins	1	2
Blackberry	1	2
Brown Rice: Pre-Germinated	1	2
Butyrate	1	2
Carbon 60	1	2
Cashew	1	2
Celery	1	2
Celery Oil	1	2
Chia	2	2
Citrus Triterpenoids	1	2
Cordyceps sinensis	1	2
Creatine	1	2
Crocetin	1	2
Diosgenin	1	2
Diosmin	1	2
EPA (Eicosapentaenoic Acid)	2	2
Essential Oils: Unspecified	1	2
Evening Primrose Oil	1	2
Geranium	1	2
Glutathione	2	2
Histidine	1	2
Isothiocyanate	1	2
Lactobacillus fermentum	1	2
Lactobacillus reuteri	1	2
Lotus	1	2
Lupeol	1	2
Magnolol	2	2
Maitake Mushroom	2	2
Mango	1	2
Marigold	1	2
Medicinal Mushrooms	2	2
Niacin	1	2
Octacosanol	1	2
Olive leaf extract	1	2
Orange	1	2
Peppermint	1	2
Piperlongumine	1	2
Polyunsaturated Fatty Acids (PUFAs)	2	2
Propolis: Bee	1	2
Psyllium	1	2
Pumpkin Seeds	1	2
Purslane	1	2
Red Clover	1	2
Red Wine Extract	2	2
Rice Bran	1	2
Royal Jelly	2	2
Schisandra	1	2
Silymarin	1	2
Sinomenine	1	2
Soy Protein	1	2
Tetrahydrocurcumin	1	2
Tocotrienol: Delta	1	2
Tocotrienols	1	2
Turkey Tail Mushroom	1	2
Turmerones	1	2
Ubiquinol	1	2
Velvet antler	1	2
Vinpocetine	2	2
Vitamin K	2	2
Vitexins	1	2
Xanthones	2	2
Zinc	1	2
18β-Glycyrrhetinic Acid	1	1
Algae	1	1
Astragalus	1	1
Avocado	1	1
Bamboo	1	1
Basil	1	1
Bee Propolis	1	1
Bergamot	1	1
Bisdemethoxycurcumin	1	1
Bromelain	1	1
Cannabinoids: Synthetic	1	1
Capsaicin	1	1
Carnosol	1	1
Carrot	1	1
Chrysanthemum Indicum	1	1
Cucurbitacin E	1	1
Cumin	1	1
Cysteine (see N-Acetylcysteine)	1	1
Delphinidin	1	1
Elderberry	1	1
Essential Fatty Acids	1	1
Garlic: Aged	1	1
Genipin	1	1
Ginseng	1	1
Glycitein	1	1
Glycyrrhiza uralensis	1	1
Harmine	1	1
Herb Bennet	1	1
Honeysuckle	1	1
Isoliquiritigenin	1	1
Jujube	1	1
Kefir	1	1
Kimchi	1	1
Lactobacillus probiotics	1	1
Lemon	1	1
Neem	1	1
Nicotinamide Mononucleotide	1	1
Oleanolic acid	1	1
Olive	1	1
Onion	1	1
Perilla	1	1
Phlorotannins	1	1
Punicic acid	1	1
Raspberry	1	1
Red Sage	1	1
Riboflavin (Vitamin B-2)	1	1
Rose	1	1
Ruta Graveolens	1	1
Seaweed	1	1
Soursop	1	1
Tauroursodeoxycholic acid	1	1
Turmeric	1	1
Vitamin K2	1	1
Water: Deuterium Depleted	1	1
Wine	1	1

Name	AC	CK
Rotenone	22	39
Pesticides	6	26
Antibiotics	3	21
Paraquat	7	14
Glyphosate	4	13
Bisphenol A	2	12
Cholinesterase Inhibitor Drugs	2	11
Antipsychotic Drugs	1	10
Dental Amalgams	1	10
Mercury	1	10
Aluminum	3	4
Aspartame	2	3
Chlorpyrifos	2	3
Aluminum Chloride	1	2
Glyphosate formulations	1	2
Lead	1	2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	2
Roundup (herbicide)	1	2
Tamoxifen	1	2
Dimethoate	1	1
Donepezil (trade name Aricept)	1	1
Galantamine	1	1
Rivastigmine	1	1
Zineb	1	1

Name	AC	CK
Tai Chi	11	152
Qigong	6	90
Exercise	21	65
Acupuncture	9	59
Exercise: Cycling	4	50
Electroacupuncture	17	49
Photobiomodulation	16	46
Ai-Chi Aquatic Exercise	3	30
Dancing	3	30
Pulsed EMF field (PEMF)	3	30
Music	4	22
Sunlight exposure	1	20
Dietary Modification: Low Carbohydrate/Ketogenic	4	14
Exercise: Aerobic	3	13
Yoga	4	13
Dietary Modification: Mediterranean Diet	1	10
Drumming	1	10
Electric Stimulation	1	10
Guided Imagery	1	10
Massage/Therapeutic Touch	1	10
Placebo Effect	1	10
Relaxation Therapy	1	10
Infrared Light	5	7
Chiropractic treatment	1	3
Melodic Intonation Therapy	2	2
Fasting/Caloric Restriction	1	1
Light Therapy: Red Colored	1	1
Magnet Therapy	1	1
Meditation	1	1
Microbiota Transfer Therapy	1	1
Mind-Body Therapies	1	1

Name	AC	CK
Vaccination: All	2	4
Electromagnetic Field Harms	1	1
Mobile Phone Radiation	1	1

[+]

Efficacy of Tai Chi on lower limb function of Parkinson's disease patients.Dec 31, 2022

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Pubmed Data : Med Sci Monit. 2019 Jan 23 ;25:666-674. Epub 2019 Jan 23. PMID: 30672512

Article Published Date : Jan 22, 2019

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Pubmed Data : N Engl J Med. 2012 Feb 9 ;366(6):511-9. PMID: 22316445

Article Published Date : Feb 09, 2012

Study Type : Human Study

Additional Links

Diseases : Parkinson's Disease, Posture Disorders

Therapeutic Actions : Tai Chi

[+]

[+]

Aquatic Ai Chi applied twice weekly may potentially reduce Parkinsonian symptoms.Jan 31, 2018

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Pubmed Data : Complement Ther Med. 2018 Feb ;36:147-153. Epub 2017 Dec 8. PMID: 29458923

Article Published Date : Jan 31, 2018

Study Type : Human Study

Additional Links

Diseases : Parkinson's Disease

Therapeutic Actions : Ai-Chi Aquatic Exercise

[+]

Ascorbate status was positively associated with cognitive function in Parkinson's disease.Sep 22, 2020

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Pubmed Data : Antioxidants (Basel). 2020 Sep 23 ;9(10). Epub 2020 Sep 23. PMID: 32977491

Article Published Date : Sep 22, 2020

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Parkinson's Disease, Vitamin C Deficiency

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Factors

[+]

Association between anticholinergic medication use and risk of dementia among patients with Parkinson's disease.Jun 27, 2019

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Pubmed Data : Pharmacotherapy. 2019 Jun 28. Epub 2019 Jun 28. PMID: 31251824

Article Published Date : Jun 27, 2019

Study Type : Human Study

Additional Links

Diseases : Dementia, Parkinson's Disease

Additional Keywords : Increased Risk

Problem Substances : Cholinesterase Inhibitor Drugs

[+]

Associations between long-term exposure to ambient air pollution and Parkinson's disease prevalence.Nov 28, 2019

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Pubmed Data : Neurochem Int. 2019 Nov 29 ;133:104615. Epub 2019 Nov 29. PMID: 31786292

Article Published Date : Nov 28, 2019

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Parkinson's Disease

Additional Keywords : Risk Factors

[+]

B. monnieri extract can improve emotional function in Parkinson's disease patients.Jan 31, 2023

Combined treatment with acupuncture and bee venom acupuncture showed promising results as a safe adjunctive therapy for PD.Sep 30, 2015

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Pubmed Data : J Altern Complement Med. 2015 Oct ;21(10):598-603. Epub 2015 Jul 31. PMID: 26230989

Article Published Date : Sep 30, 2015

[+]

Effects of dance on motor functions, cognitive functions, and mental symptoms of Parkinson's disease.Mar 31, 2015

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Pubmed Data : Complement Ther Med. 2015 Apr ;23(2):210-9. Epub 2015 Jan 16. PMID: 25847558

Article Published Date : Mar 31, 2015

Study Type : Human Study

Additional Links

Diseases : Parkinson's Disease

Therapeutic Actions : Dancing

Pharmacological Actions : Neuroprotective Agents

[+]

Effects of melatonin prolonged-release on both sleep and motor symptoms in Parkinson's disease: a preliminary evidence.May 09, 2022

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Pubmed Data : Int J Epidemiol. 2018 Aug 16. Epub 2018 Aug 16. PMID: 30124852

Article Published Date : Aug 15, 2018

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Parkinson's Disease

Additional Keywords : Risk Factors

[+]

Exposure to certain types of oral antibiotics seems to be associated with an elevated risk of Parkinson's disease.Feb 29, 2020

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Pubmed Data : Mov Disord. 2020 Mar ;35(3):431-442. Epub 2019 Nov 18. PMID: 31737957

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Melatonin levels are associated with hypothalamic gray matter volume loss and disease severity in PD patients. Mar 11, 2016

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Pubmed Data : Mov Disord. 2016 Mar 12. Epub 2016 Mar 12. PMID: 26971528

Article Published Date : Mar 11, 2016

Study Type : Human Study

Additional Links

Substances : Melatonin

Diseases : Circadian Dysregulation, Parkinson's Disease

Additional Keywords : Risk Factors

[+]

Microbiome changes in humans with Parkinson's disease after photobiomodulation therapy: A retrospective study.Jan 04, 2022

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Pubmed Data : J Pers Med. 2022 Jan 5 ;12(1). Epub 2022 Jan 5. PMID: 35055364

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Pubmed Data : Int J Epidemiol. 1996 Dec;25(6):1301-11. PMID: 9027539

Article Published Date : Dec 01, 1996

Study Type : Human Study

Additional Links

Diseases : Parkinson's Disease, Pertussis, Whooping Cough

Additional Keywords : Diseases that are Linked

[+]

Omega-3 fatty acids and vitamin E co-supplementation for 12 weeks in PD patients significantly improved gene expression of TNF-α, PPAR-γ and LDLR.Dec 31, 2018

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Pubmed Data : Clin Neurol Neurosurg. 2019 Jan ;176:116-121. Epub 2018 Dec 8. PMID: 30554092

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Pubmed Data : Medicines (Basel). 2017 Apr 23 ;4(2). Epub 2017 Apr 23. PMID: 28930237

[+]

Safety and tolerability of cannabidiol in Parkinson disease.Dec 31, 2019

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Pubmed Data : Cannabis Cannabinoid Res. 2020 ;5(4):326-336. Epub 2020 Dec 15. PMID: 33381646

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Pubmed Data : Gait Posture. 2008 Oct;28(3):456-60. Epub 2008 Apr 18. PMID: 18378456

Article Published Date : Oct 01, 2008

Study Type : Human Study

Additional Links

Diseases : Parkinson's Disease

Therapeutic Actions : Tai Chi

[+]

Tai Chi had the potential to slow down the progression of symptoms of Parkinson's disease and delayed the introduction of levodopa.Dec 31, 2019

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Pubmed Data : Braz J Med Biol Res. 2020 ;53(2):e9171. Epub 2020 Feb 10. PMID: 32049101

Article Published Date : Dec 31, 2019

Pubmed Data : J Neural Transm. 2015 Sep 5. Epub 2015 Sep 5. PMID: 26343034

Article Published Date : Sep 04, 2015

Study Type : Human Study

Additional Links

Diseases : Endothelial Dysfunction, Parkinson's Disease, Vitamin D Deficiency

[+]

These findings suggest that the intake of some flavonoids may reduce Parkinson’s disease risk.Apr 09, 2012

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Pubmed Data : Neurology. 2012 Apr 10 ;78(15):1138-45. Epub 2012 Apr 4. PMID: 22491871

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Pubmed Data : Sleep Breath. 2022 09 ;26(3):1023-1031. Epub 2021 Aug 17. PMID: 34403081

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : 5-HTP (5-Hydroxytryptophan)

Diseases : Parkinson's Disease, Sleep Disorders

[+]

This study suggested that exercises as inexpensive, non-invasive and easy-to-implement strategies could be applied for Parkinson's disease patients.Apr 26, 2021

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Pubmed Data : BMC Pharmacol Toxicol. 2022 Jul 12 ;23(1):47. Epub 2022 Jul 12. PMID: 35820950

Article Published Date : Jul 11, 2022

Study Type : Human In Vitro

Additional Links

Substances : Resveratrol

Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Parkinson's Disease

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

Rhus coriaria L. extracts could represent a potential nutraceutical approach to Parkinson's disease.Oct 22, 2022

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[+]

Targeting the differentiation of astrocytes by Bilobalide in the treatment of Parkinson's disease model.Aug 28, 2022

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Pubmed Data : Int J Neurosci. 2022 Aug 29:1-18. Epub 2022 Aug 29. PMID: 36037147

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Pubmed Data : Cureus. 2021 Dec ;13(12):e20775. Epub 2021 Dec 28. PMID: 35111460

Article Published Date : Nov 30, 2021

Study Type : Human: Case Report

Additional Links

Substances : Ashwagandha

Diseases : Parkinson's Disease, Restless Legs Syndrome

[+]

Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides.Jul 15, 2020

Pubmed Data : Int J Mol Sci. 2016 ;17(1). Epub 2016 Jan 15. PMID: 26784178

Article Published Date : Dec 31, 2015

Pharmacological Actions : Neuroprotective Agents

[+]

Aerobic exercise improves motor dysfunction in Parkinson's model.May 26, 2024

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Antiparkinsonian activity of Cucurbita pepo seeds along with possible underlying mechanism.Mar 23, 2021

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Pubmed Data : Metab Brain Dis. 2021 Mar 24. Epub 2021 Mar 24. PMID: 33759084

Article Published Date : Mar 23, 2021

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seeds

Diseases : Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Apium graveolens extracts could offer a novel approach to the treatment of Parkinsonism.Mar 19, 2018

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Bacopa monnieri alleviates paraquat induced toxicity in Drosophila.Nov 30, 2018

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Pubmed Data : Neurochem Int. 2018 Dec ;121:98-107. Epub 2018 Oct 5. PMID: 30296463

Beneficial effect of rice bran extract against rotenone-induced experimental Parkinson's disease.Jan 24, 2021

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Pubmed Data : Curr Mol Pharmacol. 2021 Jan 25. Epub 2021 Jan 25. PMID: 33573588

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Pubmed Data : Inflammopharmacology. 2008 Apr;16(2):96-9. PMID: 18408903

Article Published Date : Apr 01, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin, Flavonoids, Polyphenols, Tetrahydrocurcumin

Diseases : Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Caffeic acid phenethyl ester prevented the neurodegenerations in brain tissue in chlorpyrifos induced Parkinson's disease.Dec 31, 2017

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Pubmed Data : Pestic Biochem Physiol. 2018 Jan ;144:36-41. Epub 2017 Nov 10. PMID: 29463406

Carnosic acid alleviates levodopa-induced dyskinesia and cell death.Dec 31, 2020

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Chlorogenic acid supplementation shows its therapeutic ability by reducing the oxidative stress and neuroinflammation in MPTP-intoxicated mice.Dec 31, 2017

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Pubmed Data : Acta Histochem. 2018 Dec 17. Epub 2018 Dec 17. PMID: 30573341

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Pubmed Data : Transl Neurodegener. 2012 ;1(1):16. Epub 2012 Aug 20. PMID: 23210631

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Curcumin may be effective in preventing or slowing the progression of Parkinson's Disease.Sep 30, 2015

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Pubmed Data : Brain Res Bull. 2020 Aug 23 ;164:55-64. Epub 2020 Aug 23. PMID: 32846198

Article Published Date : Aug 22, 2020

Study Type : Animal Study

Additional Links

Substances : Echinacea

Diseases : Brain Inflammation , Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents

[+]

Echinacoside protects dopaminergic neurons.Dec 31, 2021

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Pubmed Data : Heliyon. 2024 May 15 ;10(9):e30819. Epub 2024 May 7. PMID: 38774094

Article Published Date : May 14, 2024

Study Type : Animal Study

Additional Links

Diseases : Parkinson's Disease

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Neuroprotective Agents

[+]

Electroacupuncture improved intestinal motility in Parkinson's disease.Dec 31, 2021

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Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:8659462. Epub 2022 Oct 28. PMID: 36337584

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Diseases : Parkinson's Disease

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Neuroprotective Agents

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Electroacupuncture may represent an effective adjuvant therapy for motor deficits in patients with Parkinson's disease.Oct 22, 2019

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Pubmed Data : J Gerontol A Biol Sci Med Sci. 2019 Oct 23. Epub 2019 Oct 23. PMID: 31644786

Article Published Date : Oct 22, 2019

Study Type : Animal Study

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Diseases : Parkinson's Disease

Therapeutic Actions :

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