Peripheral Nerve Diseases

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29 Substances Researched for Peripheral Nerve Diseases
NameACCKFocus
Cannabidiol110Locked
Delta-tetrahydrocannabinol (THC)110Locked
Curcumin36Locked
Lion's Mane (Hericium Erinaceus)24Locked
Puerarin24Locked
Thiamine (B-1) 24Locked
Berberine12Locked
Bergamot12Locked
Blueberry12Locked
Citrus naringin12Locked
EGCG (Epigallocatechin gallate)12Locked
Fermented Foods and Beverages12Locked
Gastrodin22Locked
Ginkgo biloba12Locked
Goldenthread12Locked
Isoflavones12Locked
Natto 12Locked
Pantothenic Acid (Vitamin B-5)12Locked
Riboflavin (Vitamin B-2)12Locked
Thymoquinone12Locked
Velvet antler12Locked
Vitamin B-1212Locked
Vitamin B-3 (Niacin)12Locked
Vitamin B-612Locked
Vitamin B1212Locked
Vitamin B12: methylcobalamin 12Locked
Vitamin E: alpha tocopherol12Locked
Dogwood11Locked
Gotu Kola11Locked
6 Therapeutic Actions Researched for Peripheral Nerve Diseases
NameACCKFocus
Photobiomodulation611Locked
Mud therapy 110Locked
Laser Treatment 23Locked
Dietary Modification: Low Carbohydrate/Ketogenic12Locked
Electric Stimulation 12Locked
Exercise12Locked

View the Evidence:
37 Abstracts with Peripheral Nerve Diseases Research

[+]

Mud therapy may have therapeutic value in reducing inflammation and improving the immune status of patients with traumas of the peripheral nervous system.Mar 01, 2006

Pubmed Data : Georgian Med News. 2006 Mar(132):72-6. PMID: 16636386
Article Published Date : Mar 01, 2006
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Peripheral Nerve Diseases, Peripheral Nervous System Diseases
Therapeutic Actions : Mud therapy
[+]

Tai chi chuan exercise improves fasting blood glucose and peripheral nerve conduction velocities in type 2 diabetic patients. Nov 01, 2009

Pubmed Data : J Rehabil Med. 2009 Nov;41(11):924-9. PMID: 19841845
Article Published Date : Nov 01, 2009
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Peripheral Nerve Diseases, Peripheral Neuropathies
[+]

THC/CBD spray was beneficial for the majority of patients with PNP associated with diabetes or allodynia.Dec 31, 2014

Pubmed Data : J Neurol. 2015 Jan ;262(1):27-40. Epub 2014 Sep 30. PMID: 25270679
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)
Diseases : Neuropathic Pain, Peripheral Nerve Diseases
Pharmacological Actions : Analgesics
[+]

A nanofiber sheet incorporating vitamin B12 promotes nerve regeneration. Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plast Reconstr Surg Glob Open. 2019 Dec ;7(12):e2538. Epub 2019 Dec 12. PMID: 32537295
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Vitamin B12: methylcobalamin
Diseases : Nerve Injuries, Peripheral Nerve Diseases, Sciatic Nerve Crush Injury
Pharmacological Actions : Regenerative
Additional Keywords : Nerve Regeneration
[+]

Alpha-tocopherol and cyanocobalamin combination accelerates peripheral nerve healing.Jul 19, 2020

Pubmed Data : Turk Neurosurg. 2020 Jul 20. Epub 2020 Jul 20. PMID: 33575997
Article Published Date : Jul 19, 2020
Study Type : Animal Study
Additional Links
Substances : Vitamin B12, Vitamin E: alpha tocopherol
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Nerve Regeneration
[+]

B vitamins had the potential for treatment of neuroinflammation and neuroregeneration.Dec 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Dec 17 ;24(24). Epub 2019 Dec 17. PMID: 31861069
Article Published Date : Dec 16, 2019
Study Type : Animal Study
Additional Links
Substances : Pantothenic Acid (Vitamin B-5), Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin B-12, Vitamin B-3 (Niacin), Vitamin B-6
Diseases : Brain Inflammation , Nerve Injuries, Neurodegenerative Diseases, Peripheral Nerve Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Berberine promotes neurite extension and axonal regeneration in injured nerves of the peripheral nervous systemApr 01, 2012

Pubmed Data : J Med Food. 2012 Apr ;15(4):413-7. Epub 2012 Feb 8. PMID: 22316297
Article Published Date : Apr 01, 2012
Study Type : Animal Study
Additional Links
Substances : Berberine, Goldenthread
Diseases : Demyelinating Diseases, Peripheral Nerve Diseases, Peripheral Neuropathies
Pharmacological Actions : Neuritogenic
Additional Keywords : Nerve Regeneration, Remyelination, Sciatic Nerve
[+]

Curcumin and biodegradable membrane promote nerve regeneration and functional recovery after sciatic nerve transection.Dec 31, 2017

Pubmed Data : Ann Plast Surg. 2018 09 ;81(3):335-339. PMID: 30028754
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Peripheral Nerve Diseases, Sciatica
Pharmacological Actions : Neuroprotective Agents, Regenerative
Additional Keywords : Nerve Regeneration
[+]

Curcumin is capable of promoting nerve regeneration after sciatic nerve crush injury in diabetes mellitus,Nov 09, 2015

Pubmed Data : Neurosci Lett. 2015 Nov 10 ;610:139-143. Epub 2015 Nov 10. PMID: 26552010
Article Published Date : Nov 09, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Diabetic Complications, Peripheral Nerve Diseases, Sciatic Nerve Crush Injury
Pharmacological Actions : Neuroprotective Agents, Regenerative
[+]

Daily consumption of EGCG might be effective in the prevention and treatment of secondary damage related to peripheral nerve injury.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk Neurosurg. 2015 ;25(3):453-60. PMID: 26037187
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Lipid Peroxidation, Peripheral Nerve Diseases, Sciatica
Pharmacological Actions : Antioxidants
[+]

Effects of photobiomodulation with low-level laser therapy on muscle repair following a peripheral nerve injury.Mar 02, 2020

Pubmed Data : Photochem Photobiol. 2020 Mar 3. Epub 2020 Mar 3. PMID: 32125691
Article Published Date : Mar 02, 2020
Study Type : Animal Study
Additional Links
Diseases : Peripheral Nerve Diseases
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Regenerative
Additional Keywords : Muscle Regeneration
[+]

Exercise facilitates regeneration after severe nerve transection and further modulates neural plasticity.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain Behav Immun Health. 2022 Dec ;26:100556. Epub 2022 Nov 12. PMID: 36405423
Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Diseases : Nerve Injuries, Peripheral Nerve Diseases
Therapeutic Actions : Exercise
Pharmacological Actions : Neuroplasticity enhancement, Neuroprotective Agents
Additional Keywords : Nerve Regeneration
[+]

Ginkgo biloba extract has a dose dependant effect of promoting regeneration of injured peripheral nervesJan 01, 2007

Pubmed Data : Microsurgery. 2007 ;27(8):673-7. PMID: 17941104
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Neuritogenic
Additional Keywords : Nerve Regeneration, Plant Extracts
[+]

Laser treatment induces peripheral nerve regeneration.Jun 01, 2007

Pubmed Data : Photomed Laser Surg. 2007 Jun;25(3):137-43. PMID: 17603852
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Peripheral Nerve Diseases, Peripheral Neuropathies
Therapeutic Actions : Laser Treatment
Additional Keywords : Remyelination
[+]

Lion's Mane extract is capable of promoting peripheral nerve regeneration after injury in rats.Aug 25, 2014

Pubmed Data : Chin J Integr Med. 2014 Aug 26. Epub 2014 Aug 26. PMID: 25159861
Article Published Date : Aug 25, 2014
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Regenerative
Additional Keywords : Nerve Regeneration, Plant Extracts
[+]

Morphofunctional improvement of the facial nerve and muscles with repair using heterologous fibrin biopolymer and photobiomodulation.Apr 26, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2023 Apr 27 ;16(5). Epub 2023 Apr 27. PMID: 37242436
Article Published Date : Apr 26, 2023
Study Type : Animal Study
Additional Links
Diseases : Peripheral Nerve Diseases
Therapeutic Actions : Photobiomodulation
Additional Keywords : Nerve Regeneration
[+]

PBM has a positive influence on nerve regeneration results in immediate repair.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Venom Anim Toxins Incl Trop Dis. 2024 ;30:e20230093. Epub 2024 May 27. PMID: 38808073
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Peripheral Nerve Diseases
Therapeutic Actions : Photobiomodulation
Additional Keywords : Muscle Regeneration, Nerve Regeneration
[+]

Photobiomodulation triple treatment in peripheral nerve injury: Nerve and muscle response.Nov 30, 2016

Pubmed Data : Photomed Laser Surg. 2016 Dec ;34(12):638-645. PMID: 28001757
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Peripheral Nerve Diseases, Spinal Cord Injuries
Therapeutic Actions : Photobiomodulation
Additional Keywords : Nerve Regeneration
[+]

Possible involvement of the peripheral Mu-opioid system in antinociception induced by bergamot essential oil to allodynia after peripheral nerve injury.Dec 31, 2017

Pubmed Data : Neurosci Lett. 2018 11 1 ;686:127-132. Epub 2018 Sep 7. PMID: 30201308
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Bergamot
Diseases : Allodynia, Peripheral Nerve Diseases
Pharmacological Actions : Antinoceceptive
Additional Keywords : Essential Oils
[+]

Postoperative low-level laser irradiation was able to accelerate and potentialize the peripheral nerve regeneration process in rabbits within 14 days of irradiation.Sep 27, 2015

Pubmed Data : Lasers Med Sci. 2015 Sep 28. Epub 2015 Sep 28. PMID: 26415928
Article Published Date : Sep 27, 2015
Study Type : Animal Study
Additional Links
Diseases : Peripheral Nerve Diseases
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Regenerative
Additional Keywords : Significant Treatment Outcome
[+]

Puerarin ameliorates allodynia and hyperalgesia in rats with peripheral nerve injury.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2018 Jul ;13(7):1263-1268. PMID: 30028336
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Allodynia, Hyperalgesia, Peripheral Nerve Diseases
Pharmacological Actions : Analgesics
[+]

Puerarin in vitro and vivo has been shown to have a regenerative effect on damaged peripheral nerves.Jan 01, 2011

Pubmed Data : Am J Chin Med. 2011 ;39(6):1207-17. PMID: 22083991
Article Published Date : Jan 01, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Isoflavones, Puerarin
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Neuritogenic
Additional Keywords : Nerve Regeneration, Sciatic Nerve
[+]

Regenerative activity of Hericium erinaceus on axonal injury model using in vitro laser microdissection technique.Feb 28, 2019

Pubmed Data : Neurol Res. 2019 Mar ;41(3):265-274. Epub 2018 Dec 20. PMID: 30570422
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Neuritogenic, Neuroprotective Agents
Additional Keywords : Nerve Regeneration, Phytotherapy, Plant Extracts
[+]

Sciatic nerve regeneration by using collagen type I hydrogel containing naringin.Sep 10, 2019

Pubmed Data : J Mater Sci Mater Med. 2019 Sep 11 ;30(9):107. Epub 2019 Sep 11. PMID: 31512084
Article Published Date : Sep 10, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Peripheral Nerve Diseases, Sciatica
Additional Keywords : Nerve Regeneration
[+]

The effects of curcumin and blueberry on axonal regeneration after peripheral nerve injury.Jun 30, 2023

Pubmed Data : J Chem Neuroanat. 2023 Jul ;130:102260. Epub 2023 Mar 24. PMID: 36965643
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Blueberry, Curcumin
Diseases : Nerve Entrapments, Peripheral Nerve Diseases, Sciatic Nerve Crush Injury
Pharmacological Actions : Regenerative
Additional Keywords : Nerve Regeneration
[+]

The fermented soy product natto improves neurobehavioral deficits after sciatic nerve injury in rats. May 01, 2007

Pubmed Data : Phytother Res. 2007 May;21(5):401-5. PMID: 19309538
Article Published Date : May 01, 2007
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Natto
Diseases : Peripheral Nerve Diseases, Sciatica
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

These results establish that ketogenic diet and electrical stimulation promote peripheral nerve regeneration.Jan 07, 2020

Pubmed Data : Mol Nutr Food Res. 2020 Jan 8:e1900535. Epub 2020 Jan 8. PMID: 31914235
Article Published Date : Jan 07, 2020
Study Type : Animal Study
Additional Links
Diseases : Peripheral Nerve Diseases, Sciatic Nerve Crush Injury
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Electric Stimulation
Pharmacological Actions : Neuroprotective Agents
[+]

Thiamine as a peripheral neuro-protective agent in comparison with N-acetyl cysteine in axotomized rats.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2023 ;26(8):919-926. PMID: 37427326
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Thiamine (B-1)
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymoquinone exhibits a regenerative potential for the treatment of damaged peripheral nerves.Aug 07, 2018

Pubmed Data : Neurol Res. 2018 Aug 8:1-8. Epub 2018 Aug 8. PMID: 30088803
Article Published Date : Aug 07, 2018
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Neuroprotective Agents, Regenerative
Additional Keywords : Nerve Regeneration
[+]

Velvet antler polypeptide induce peripheral nerve regeneration.Dec 01, 2008

Pubmed Data : Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2008 Dec;22(12):1458-61. PMID: 19137890
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Velvet antler
Diseases : Peripheral Nerve Diseases, Peripheral Neuropathies
Pharmacological Actions : Neuritogenic
Additional Keywords : Nerve Regeneration
[+]

Blocking Smad2 signalling with loganin attenuates SW10 cell cycle arrest induced by TNF-α.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(5):e0176965. Epub 2017 May 5. PMID: 28475649
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Dogwood
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Anti-Apoptotic, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Nerve Regeneration
[+]

Centella asiatica neurodifferentiated mesenchymal stem cells promote the regeneration of peripheral nerve.Feb 07, 2020

Pubmed Data : Tissue Eng Regen Med. 2020 Feb 8. Epub 2020 Feb 8. PMID: 32036567
Article Published Date : Feb 07, 2020
Study Type : In Vitro Study
Additional Links
Substances : Gotu Kola
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Regenerative
Additional Keywords : Mesenchymal Stem Cells, Nerve Regeneration
[+]

Gastrodin modified polyurethane conduit promotes nerve repair via optimizing Schwann cells function.Jan 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioact Mater. 2022 Feb ;8:355-367. Epub 2021 Jul 2. PMID: 34541406
Article Published Date : Jan 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Gastrodin
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Regenerative
Additional Keywords : Nerve Regeneration
[+]

Gastrodin promotes the regeneration of peripheral nerves.Feb 17, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2022 Feb 18 ;22(1):45. Epub 2022 Feb 18. PMID: 35177060
Article Published Date : Feb 17, 2022
Study Type : In Vitro Study
Additional Links
Substances : Gastrodin
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Antioxidants, Brain-derived neurotrophic factor modulator, MicroRNA modulator
Additional Keywords : Nerve Regeneration
[+]

Laser phototherapy accelerates and enhances axonal growth and regeneration after injury or a reconstructive peripheral nerve procedure. Feb 01, 2009

Pubmed Data : Neurosurg Focus. 2009 Feb;26(2):E8. PMID: 19199510
Article Published Date : Feb 01, 2009
Study Type : Review
Additional Links
Diseases : Neurologic Disorders, Peripheral Nerve Diseases, Peripheral Neuropathies
Therapeutic Actions : Laser Treatment
[+]

Low-level laser effect on peripheral sciatic regeneration under the systemic inflammatory condition of periodontal disease.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Lasers Med Sci. 2020 ;11(1):56-64. Epub 2020 Jan 18. PMID: 32099628
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Periodontal Diseases, Peripheral Nerve Diseases
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Regenerative
Additional Keywords : Nerve Regeneration
[+]

Melatonin promotes peripheral nerve repair through Parkin-mediated mitophagy.Apr 29, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Free Radic Biol Med. 2022 Apr 30 ;185:52-66. Epub 2022 Apr 30. PMID: 35504358
Article Published Date : Apr 29, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Anti-Apoptotic
Additional Keywords : Nerve Regeneration

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