Pertussis

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12 Substances Researched for Pertussis
NameACCKFocus
Chinese Skullcap 24Locked
Caffeine13Locked
Black Tea12Locked
Catechin 12Locked
Coffee12Locked
Curcumin12Locked
Green Tea12Locked
Lactobacilius bulgaricus12Locked
Oak12Locked
Pine Buds12Locked
Skullcap: Chinese12Locked
St. Johns Wort12Locked
1 Problem Substances Researched for Pertussis
NameACCKFocus
Antibiotics120Locked
4 Problematic Actions Researched for Pertussis
NameACCKFocus
Vaccination: Pertussis1270Locked
Vaccination: All752Locked
Vaccination: Diphtheria-Pertussis-Tetanus743Locked
Vaccination: Tetanus110Locked

View the Evidence:
25 Abstracts with Pertussis Research

[+]

Antibiotics are effective in eliminating B. pertussis from patients with the disease, rendering them non-infectious, but do not alter the subsequent clinical course of the illness.Dec 31, 2004

Pubmed Data : Cochrane Database Syst Rev. 2005(1):CD004404. Epub 2005 Jan 25. PMID: 15674946
Article Published Date : Dec 31, 2004
Study Type : Meta Analysis
Additional Links
Diseases : Pertussis, Whooping Cough
Problem Substances : Antibiotics
[+]

Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Euro Surveill. 2019 Feb ;24(7). PMID: 30782265
Article Published Date : Jan 31, 2019
Study Type : Meta Analysis
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

DPT vaccines have been associated with recurrent seizures.Oct 01, 1984

Pubmed Data : Am J Dis Child. 1984 Oct;138(10):908-11. PMID: 6206715
Article Published Date : Oct 01, 1984
Study Type : Human Study
Additional Links
Diseases : Pertussis, Seizures, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus
[+]

In Kings County Washington, between 2002-2007, of the 176 confirmed cases of pertussis in infants under age 1 seventy-seven percent were age-appropriately vaccinated.Jul 01, 2011

Pubmed Data : Arch Pediatr Adolesc Med. 2011 Jul ;165(7):647-52. PMID: 21727277
Article Published Date : Jul 01, 2011
Study Type : Human Study
Additional Links
Diseases : Pertussis
Additional Keywords : Vaccine Resistance
Anti Therapeutic Actions : Vaccination: All, Vaccination: Pertussis
[+]

Neurotoxicity from pertussis infection may be casually related to the pathogenesis of Parkinson's disease.Dec 01, 1996

Pubmed Data : Int J Epidemiol. 1996 Dec;25(6):1301-11. PMID: 9027539
Article Published Date : Dec 01, 1996
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease, Pertussis, Whooping Cough
Additional Keywords : Diseases that are Linked
[+]

Pertussis epidemic despite high levels of vaccination coverage with acellular pertussis vaccine.Nov 07, 2013

Article Published Date : Nov 07, 2013
Study Type : Human Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus
[+]

Polymorphisms in the VDR gene may affect immune activation and the clinical outcome of B. pertussis infection.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(2):e0149576. Epub 2016 Feb 19. PMID: 26894582
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : Pertussis, Whooping Cough
Additional Keywords : Genomic Variation
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Since the 1993 pertussis epidemic in Cincinnati occurred primarily among children who had been appropriately immunized, it is clear that the whole-cell pertussis vaccine failed to give full protection against the disease.Jul 07, 1994

Pubmed Data : N Engl J Med. 1994 Jul 7;331(1):16-21. PMID: 8202096
Article Published Date : Jul 07, 1994
Study Type : Human Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis
[+]

Vaccinated children and adults may serve as reservoirs for silent pertussis infection and become potential transmitters to unprotected infants.Sep 01, 2000

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Emerg Infect Dis. 2000 Sep-Oct;6(5):526-9. PMID: 10998384
Article Published Date : Sep 01, 2000
Study Type : Human Study
Additional Links
Diseases : Pertussis, Vaccine-induced Toxicity , Whooping Cough
Additional Keywords : Reservoirs For Infection
Anti Therapeutic Actions : Vaccination: All, Vaccination: Pertussis
[+]

Vaccinating mothers with TdaP postpartum is not sufficient to protect infants younger than 6 months from pertussis illness.Nov 10, 2011

Pubmed Data : Clin Infect Dis. 2011 Nov 10. Epub 2011 Nov 10. PMID: 22075790
Article Published Date : Nov 10, 2011
Study Type : Human Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis, Vaccination: Tetanus
[+]

A case report of a 5-year-old, fully immunized boy with PCR proven consecutive B. pertussis and B. parapertussis infections.Jul 05, 2016

Pubmed Data : Pediatr Infect Dis J. 2016 Jul 6. Epub 2016 Jul 6. PMID: 27391699
Article Published Date : Jul 05, 2016
Study Type : Human: Case Report
Additional Links
Diseases : Parapertussis, Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Caffeine might improve outcomes in pertussis by preventing apnoea and decreasing pulmonary complications.Mar 27, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ Case Rep. 2018 Mar 28 ;2018. Epub 2018 Mar 28. PMID: 29592985
Article Published Date : Mar 27, 2018
Study Type : Human: Case Report
Additional Links
Substances : Caffeine
Diseases : Pertussis, Whooping Cough
Additional Keywords : Risk Reduction
[+]

Chinese skullcap contains a compound known as baicalin which has protective effects on infective brain edema in rats caused by the injfection of pertussis bacilli - Article 2. Aug 01, 1998

Pubmed Data : Zhonghua Yi Xue Za Zhi. 1998 Aug;78(8):630-2. PMID: 11038818
Article Published Date : Aug 01, 1998
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Pertussis
Pharmacological Actions : Anti-Bacterial Agents
[+]

Chinese skullcap contains a compound known as baicalin which has protective effects on infective brain edema in rats caused by the injfection of pertussis bacilli.Mar 01, 1985

Pubmed Data : Arch Pathol Lab Med. 1985 Mar;109(3):283-6. PMID: 12212190
Article Published Date : Mar 01, 1985
Study Type : Animal Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Pertussis
Pharmacological Actions : Neuroprotective Agents
[+]

Chinese skullcap contains a compound known as baicalin which reduces intracranial hypertension associated with pertussis infection in the brain of rabbits.Apr 01, 1999

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 1999 Apr;19(4):224-6. PMID: 11783272
Article Published Date : Apr 01, 1999
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Intracranial Hypertension: Infection-Caused, Pertussis
[+]

Curcumin reduces pertussis-induced infectious brain edema in rats.Dec 01, 2006

Pubmed Data : Biopharm Drug Dispos. 2006 Dec;27(9):407-20. PMID: 14723822
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Diseases, Brain Edema, Pertussis
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Green tea (EGCG), black tea and coffee may protect against Bordetella pertussis infection.Dec 01, 2006

Pubmed Data : Chem Biol Interact. 2006 Dec 1;164(1-2):102-14. Epub 2006 Sep 16. PMID: 1402092
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Black Tea, Catechin , Coffee, Green Tea
Diseases : Pertussis, Whooping Cough
Pharmacological Actions : Anti-Bacterial Agents
[+]

Lactobacillus bulgaricus contains a substance which may improve immunogenicity and reduce the toxicity of pertussis vaccination (whooping cough vaccine).Jan 01, 1986

Pubmed Data : Zh Mikrobiol Epidemiol Immunobiol. 1986 Jan;(1):62-5. PMID: 3705806
Article Published Date : Jan 01, 1986
Study Type : Animal Study
Additional Links
Substances : Lactobacilius bulgaricus
Diseases : Pertussis, Whooping Cough
Additional Keywords : Vaccine Side Effect Attenuation
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Natural plant extracts from oak bark, St. john's work leaves and pine buds may have therapeutic activity in supporting natural immunity from Staphylococcus aureus and Bordetella pertussis.Apr 01, 1986

Pubmed Data : Zh Mikrobiol Epidemiol Immunobiol. 1986 Apr(4):71-5. PMID: 3012909
Article Published Date : Apr 01, 1986
Study Type : Animal Study
Additional Links
Substances : Oak, Pine Buds, St. Johns Wort
Diseases : Pertussis, Whooping Cough
Pharmacological Actions : Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Despite high coverage rates for primary immunization in infants and children pertussis incidence rates are increasing.May 01, 2005

Pubmed Data : Pediatr Infect Dis J. 2005 May;24(5 Suppl):S10-8. PMID: 15876918
Article Published Date : May 01, 2005
Study Type : Review
Additional Links
Diseases : Pertussis
Additional Keywords : Vaccine Resistance
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis
[+]

Pathogen adaptation has contributed to the resurgence of pertussis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genome Announc. 2015;3(6). Epub 2015 Nov 25. PMID: 26607899
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Pertussis
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis
[+]

Substantial evidence supports the idea that pertussis toxin is a major contributor to pertussis pathology, including the severe respiratory symptoms associated with this disease.Oct 31, 2015

Pubmed Data : Pathog Dis. 2015 Nov ;73(8). Epub 2015 Sep 21. PMID: 26394801
Article Published Date : Oct 31, 2015
Study Type : Review
Additional Links
Diseases : Pertussis, Whooping Cough
[+]

The study results can be interpreted as a partial genetic escape of pathogenic strains of B. pertussis beyond the reach of the pertussis vaccines.Dec 31, 2014

Pubmed Data : Epidemiol Mikrobiol Imunol. 2015 ;64(3):130-8. PMID: 26448300
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

These results suggest that the immune pressure of vaccination is one major driving force for the evolution of B. pertussis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:12888. Epub 2015 Aug 18. PMID: 26283022
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Underestimation of central nervous system complications after pertussis immunization appears to be prevalent.Aug 01, 1991

Pubmed Data : Acta Paediatr Jpn. 1991 Aug;33(4):421-7. PMID: 1792899
Article Published Date : Aug 01, 1991
Study Type : Review
Additional Links
Diseases : Pertussis
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis

Copyright: ilona75 / 123RF Stock Photo

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