Polycystic Ovary Syndrome

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28 Substances Researched for Polycystic Ovary Syndrome
NameACCKFocus
Inositol440Locked
Folic Acid 330Locked
Buckwheat220Locked
D-Chiro-Inositol220Locked
Licorice220Locked
Vitamin D120Locked
Almond110Locked
Alpha-Lipoic Acid110Locked
Arginine110Locked
B-complex110Locked
Chinense Herbal Formula: Jinqi Jiangtang 110Locked
Chinese Herbal Formula: Tiangui Fang110Locked
Cinnamon110Locked
Fenugreek110Locked
Myo-inositol110Locked
Omega-3 Fatty Acids110Locked
Selenium110Locked
Spearmint110Locked
Testosterone110Locked
Vinegar110Locked
Walnut110Locked
Ginseng (Korean)24Locked
Lactobacillus probiotics12Locked
Resveratrol22Locked
Thymoquinone12Locked
Tribulus12Locked
Berberine11Locked
Puerarin11Locked
2 Problem Substances Researched for Polycystic Ovary Syndrome
NameACCKFocus
Insulin 110Locked
Octylphenol 110Locked
4 Therapeutic Actions Researched for Polycystic Ovary Syndrome
NameACCKFocus
Acupuncture541Locked
Dietary Modification: Low Starch/Low Dairy 110Locked
Integrative Medicine110Locked
Moxibustion110Locked

View the Evidence:
143 Abstracts with Polycystic Ovary Syndrome Research

[+]

Berberine showed a promising prospect in treating polycystic ovary syndrome patients with insulin resistance.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:2532935. Epub 2018 Nov 14. PMID: 30538756
Article Published Date : Dec 31, 2017
Study Type : Meta Analysis, Review
Additional Links
Substances : Berberine
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
[+]

BPA might be involved in the insulin-resistance and hyperandrogenism of polycystic ovary syndrome.Nov 29, 2017

Pubmed Data : Gynecol Endocrinol. 2017 Nov 30:1-8. Epub 2017 Nov 30. PMID: 29191127
Article Published Date : Nov 29, 2017
Study Type : Meta Analysis, Review
Additional Links
Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome
Problem Substances : Bisphenol A
[+]

N-acetyl-cysteine may be considered as an alternative supplement to metformin in PCOS patients.Nov 20, 2019

Pubmed Data : Gynecol Endocrinol. 2019 Nov 21:1-7. Epub 2019 Nov 21. PMID: 31749393
Article Published Date : Nov 20, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Polycystic Ovary Syndrome
[+]

Serum 25-hydroxyvitamin D, follicle stimulating hormone and sex hormone-binding globulin were significantly lower in PCOS patients than controls.Aug 09, 2017

Pubmed Data : Eur J Clin Invest. 2017 Aug 10. Epub 2017 Aug 10. PMID: 28795765
Article Published Date : Aug 09, 2017
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Polycystic Ovary Syndrome, Vitamin D Deficiency
[+]

Serum level of vitamin D was associated with the risk of polycystic ovary syndrome.Sep 13, 2015

Pubmed Data : J Obstet Gynaecol Res. 2015 Sep 14. Epub 2015 Sep 14. PMID: 26370491
Article Published Date : Sep 13, 2015
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Polycystic Ovary Syndrome, Vitamin D Deficiency
Additional Keywords : Risk Factors, Risk Reduction
[+]

Vitamin D supplementation had beneficial on biomarkers of inflammation and oxidative stress among women with polycystic ovary syndrome.Feb 22, 2018

Pubmed Data : Horm Metab Res. 2018 Feb 23. Epub 2018 Feb 23. PMID: 29475212
Article Published Date : Feb 22, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Vitamin D
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Vitamin D supplementation improves markers of polycystic ovarian syndrome.Apr 01, 2020

Pubmed Data : Exp Ther Med. 2020 Apr ;19(4):2641-2649. Epub 2020 Feb 11. PMID: 32256745
Article Published Date : Apr 01, 2020
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Androgen, Hypolipidemic, Insulin Sensitizers
[+]

Vitamin D supplementation is sufficient for decreasing serum triglyceride.Dec 08, 2016

Pubmed Data : Arch Gynecol Obstet. 2016 Dec 9. Epub 2016 Dec 9. PMID: 27933387
Article Published Date : Dec 08, 2016
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Hypolipidemic
[+]

"Hyperandrogenism in women with polycystic ovary syndrome persists after menopause."Mar 01, 2011

Pubmed Data : J Clin Endocrinol Metab. 2011 Mar ;96(3):623-31. Epub 2010 Dec 22. PMID: 21177795
Article Published Date : Mar 01, 2011
Study Type : Human Study
Additional Links
Diseases : Adrenal Hyperandrogenism, Polycystic Ovary Syndrome
Additional Keywords : Diseases that are Linked
[+]

A single bout of electroacupuncture remodels epigenetic and transcriptional changes in adipose tissue in polycystic ovary syndrome.Jan 29, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Jan 30 ;8(1):1878. Epub 2018 Jan 30. PMID: 29382850
Article Published Date : Jan 29, 2018
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Electroacupuncture
Additional Keywords : Epigenetic Modification
[+]

Abdominal acupuncture treatment can improve the endocrine and metabolic function of patients with obesity-type polycystic ovarian syndrome. Aug 01, 2010

Pubmed Data : Zhen Ci Yan Jiu. 2010 Aug;35(4):298-302. PMID: 21090334
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Diseases : Obesity, Polycystic Ovary Syndrome
Therapeutic Actions : Acupuncture
[+]

Acupuncture at Zhibian through Shuidao could significantly improve the basic temperature of patients with polycystic ovary syndrome, and regulate hormone level of reproductive endocrine.Apr 30, 2015

Pubmed Data : Zhongguo Zhen Jiu. 2015 May ;35(5):461-4. PMID: 26255520
Article Published Date : Apr 30, 2015
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Acupuncture
Additional Keywords : Significant Treatment Outcome
[+]

Acupuncture can effectively reduce FINS, HOMA-IR and WC levels in PCOS patients with abdominal obesity.Apr 24, 2018

Pubmed Data : Zhen Ci Yan Jiu. 2018 Apr 25 ;43(4):255-9. PMID: 29888581
Article Published Date : Apr 24, 2018
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Acupuncture
[+]

Administration of B-group vitamins reduces circulating homocysteine in polycystic ovarian syndrome patients treated with metformin. Jun 01, 2005

Pubmed Data : Hum Reprod. 2005 Jun;20(6):1521-8. Epub 2005 Mar 24. PMID: 15790610
Article Published Date : Jun 01, 2005
Study Type : Human Study
Additional Links
Substances : B-complex, Folic Acid
Diseases : Polycystic Ovary Syndrome
Additional Keywords : Drug Side Effect Attenuation
[+]

Adrenal androgen excess in the polycystic ovary syndrome patients is related to an exaggerated secretory response of the adrenal cortex for DHEA and androstenedione (A4).Jul 01, 1998

Pubmed Data : J Clin Endocrinol Metab. 1998 Jul ;83(7):2317-23. PMID: 9661602
Article Published Date : Jul 01, 1998
Study Type : Human Study
Additional Links
Diseases : Adrenal Hyperandrogenism, Androstenedione (A4): High, DHEA: High, Polycystic Ovary Syndrome
[+]

An 8-week low-starch/low-dairy diet resulted in weight loss, improved insulin sensitivity and reduced testosterone in women with PCOS.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Obes Weight Loss Ther. 2015 Apr ;5(2). PMID: 26225266
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Dietary Modification: Low Starch/Low Dairy
Additional Keywords : Risk Reduction
[+]

Bisphenol A may play a role in the aetiopathogenesis of polycystic ovary syndrome in adolescent girls.Mar 31, 2015

Pubmed Data : Acta Paediatr. 2015 Apr ;104(4):e171-7. Epub 2015 Feb 3. PMID: 25469562
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome
Problem Substances : Bisphenol A
[+]

Bodily retention of environmental organic pollutants-including PCBs, pesticides and PAHs-was associated with PCOS.Jul 31, 2015

Pubmed Data : Hum Reprod. 2015 Aug ;30(8):1964-73. Epub 2015 Jun 3. PMID: 26040477
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Additional Keywords : Risk Factors
Problem Substances : Organochlorine pesticides, Pesticides, Polychlorinated biphenyls (PCBs)
[+]

BPA may play a major role in the pathogenesis of polycystic ovarian syndrome.Nov 30, 2017

Pubmed Data : Acta Med Iran. 2017 Dec ;55(12):759-764. PMID: 29373882
Article Published Date : Nov 30, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Increased Risk, Polycystic Ovary Syndrome
Problem Substances : Bisphenol A
[+]

Cinnamon reduces insulin resistance parameters in polycystic ovary syndrome.Apr 01, 2001

Pubmed Data : Nutrition. 2001 Apr;17(4):315-21. PMID: 17296187
Article Published Date : Apr 01, 2001
Study Type : Human Study
Additional Links
Substances : Cinnamon
Diseases : Polycystic Ovary Syndrome
[+]

Cinnamon supplementation improved antioxidant status and serum lipid profile in women with PCOS.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2018 Jan ;8(1):128-133. Epub 2017 May 19. PMID: 29322000
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Cinnamon
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants, Hypolipidemic
[+]

Co-administration of vitamin D and probiotic for 12 weeks to women with polycystic ovary syndrome had beneficial effects.Jan 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ovarian Res. 2019 Jan 21 ;12(1):5. Epub 2019 Jan 21. PMID: 30665436
Article Published Date : Jan 20, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : C-Reactive Protein, Inflammation, Oxidative Stress, Polycystic Ovary Syndrome
Pharmacological Actions : Malondialdehyde Down-regulation
[+]

Coenzyme Q10 and vitamin E had beneficial effects on cardiometabolic outcomes among women with polycystic ovary syndrome.Jan 31, 2019

Pubmed Data : Arch Med Res. 2019 Feb ;50(2):1-10. Epub 2019 May 21. PMID: 31349945
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Vitamin E
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Hypolipidemic
Additional Keywords : Natural Substance Synergy
[+]

Consuming daily synbiotic pomegranate juice improved metabolic, oxidative, inflammatory, and blood pressure outcomes in females with PCOS.Nov 10, 2019

Pubmed Data : J Endocrinol Invest. 2019 Nov 11. Epub 2019 Nov 11. PMID: 31713129
Article Published Date : Nov 10, 2019
Study Type : Human Study
Additional Links
Substances : Pomegranate
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Cardioprotective
[+]

Controlled-release alpha lipoic acid has a therapeutic effect in lean, nondiabetic patients with polycystic ovary syndrome.Mar 01, 2010

Pubmed Data : J Diabetes Sci Technol. 2010 Mar;4(2):359-64. Epub 2010 Mar 1. PMID: 20307398
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Hyperinsulinism, Insulin Resistance, Oxidative Stress, Polycystic Ovary Syndrome
[+]

CoQ10 and vitamin E supplementation had beneficial effects on serum FBS and insulin levels as well as HOMA-IR and total testosterone levels.Sep 06, 2018

Pubmed Data : J Clin Endocrinol Metab. 2018 Sep 7. Epub 2018 Sep 7. PMID: 30202998
Article Published Date : Sep 06, 2018
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Vitamin E
Diseases : Polycystic Ovary Syndrome
Additional Keywords : Natural Substance Synergy
[+]

CoQ10 intake for 12 weeks in PCOS women significantly improved gene expression of LDLR, PPAR-γ, IL-1, IL-8 and TNF-α.Sep 25, 2017

Pubmed Data : Gynecol Endocrinol. 2017 Sep 26:1-6. Epub 2017 Sep 26. PMID: 28949260
Article Published Date : Sep 25, 2017
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

CoQ10 supplementation had beneficial effects in subjects with PCOS, involving glucose metabolism, serum total and LDL-cholesterol levels.Dec 01, 2016

Pubmed Data : Clin Endocrinol (Oxf). 2016 Dec 2. Epub 2016 Dec 2. PMID: 27911471
Article Published Date : Dec 01, 2016
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anticholesteremic Agents
[+]

Curcumin seems to be an efficient reducer of oxidative stress related complications in patients with PCOS.Jan 07, 2020

Pubmed Data : Diabetes Metab Syndr. 2020 Jan 8 ;14(2):77-82. Epub 2020 Jan 8. PMID: 31991296
Article Published Date : Jan 07, 2020
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants, SIRT1 Activator, Superoxide Dismutase Up-regulation
[+]

D-chiro-inositol has a therapeutic effect in lean women with the polycystic ovary syndrome.Nov 01, 2002

Pubmed Data : Endocr Pract. 2002 Nov-Dec;8(6):417-23. PMID: 15251831
Article Published Date : Nov 01, 2002
Study Type : Human Study
Additional Links
Substances : Buckwheat, D-Chiro-Inositol, Inositol
Diseases : Hypertension, Metabolic Syndrome X, Polycystic Ovary Syndrome
[+]

Electroacupuncture improves oocytes' growth in patients with polycystic ovary syndrome.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Acupunct. 2019 Dec 1 ;31(6):379-383. Epub 2019 Dec 13. PMID: 31871526
Article Published Date : Nov 30, 2019
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Electroacupuncture
[+]

Endocrine disruptors such as BPA could modify neuroendocrine, reproductive, and metabolic regulation favouring PCOS development in adolescents.Jun 19, 2019

Pubmed Data : Gynecol Endocrinol. 2019 Jun 20:1-4. Epub 2019 Jun 20. PMID: 31219355
Article Published Date : Jun 19, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A , Phthalates
[+]

Exercise improves psychological well-being in women with polycystic ovary syndrome.Dec 31, 2019

Pubmed Data : Adv Exp Med Biol. 2020 ;1228:123-136. PMID: 32342454
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Exercise
[+]

Flaxseed oil omega-3 supplementation for 12 weeks in women with PCOS had beneficial effects.Mar 31, 2018

Pubmed Data : Exp Clin Endocrinol Diabetes. 2018 Apr ;126(4):222-228. Epub 2017 Nov 8. PMID: 29117618
Article Published Date : Mar 31, 2018
Study Type : Human Study
Additional Links
Substances : Flaxseed
Diseases : Inflammation, Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Hypolipidemic
[+]

Folate improves the effect of metformin treatment on vascular endothelial function in women with polycystic ovary sydrome. Feb 01, 2010

Pubmed Data : Diabetes Care. 2010 Feb;33(2):246-51. Epub 2009 Nov 23. PMID: 19933994
Article Published Date : Feb 01, 2010
Study Type : Human Study
Additional Links
Substances : Folic Acid
Diseases : Drug Induced Toxicity: Metformin, Polycystic Ovary Syndrome
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Folate supplementation for 8 weeks among women with PCOS had beneficial effects on metabolic profiles.Jun 30, 2014

Pubmed Data : Mol Nutr Food Res. 2014 Jul ;58(7):1465-73. Epub 2014 May 15. PMID: 24828019
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Substances : Folate, Folic Acid
Diseases : Polycystic Ovary Syndrome
[+]

Furocyst was efficacious in ameliorating the symptoms of polycystic ovary syndrome.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Med Sci. 2015 ;12(10):825-31. Epub 2015 Oct 3. PMID: 26516311
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Fenugreek
Diseases : Polycystic Ovary Syndrome
Additional Keywords : Plant Extracts
[+]

Girls with PCOS and IR more hirsute, more AN, lower SHBG and higher fasting insulin levelsMay 31, 2010

Pubmed Data : J Pediatr Adolesc Gynecol. 2010 Jun ;23(3):158-61. Epub 2009 Dec 5. PMID: 19963413
Article Published Date : May 31, 2010
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Problem Substances : Insulin
[+]

in the form of a new beverage can improve insulin resistance, insulin, testosterone level, BMI, weight and waist circumference in PCOS. Dec 31, 2018

Pubmed Data : Nutr Metab Cardiovasc Dis. 2019 02 ;29(2):201-208. Epub 2018 Jul 17. PMID: 30538082
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Pomegranate, Probiotics
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers
[+]

Increasing protein intake and restricting simple sugar intake may be therapeutic in polycystic ovary syndrome (PCOS)Mar 01, 2007

Pubmed Data : Am J Clin Nutr. 2007 Mar;85(3):688-94. PMID: 17344488
Article Published Date : Mar 01, 2007
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
[+]

Inositol improves ovarian function in women with oligomenorrhea and polycystic ovaries.Nov 01, 2003

Pubmed Data : Eur Rev Med Pharmacol Sci. 2003 Nov-Dec;7(6):151-9. PMID: 15206484
Article Published Date : Nov 01, 2003
Study Type : Human Study
Additional Links
Substances : Inositol
Diseases : Oligomenorrhea, Polycystic Ovary Syndrome
[+]

L-arginine appears to counteract the hypertensive properties of estradiol in patients with PCOS.Dec 01, 2010

Pubmed Data : Gynecol Endocrinol. 2010 Dec;26(12):861-8. Epub 2010 Jul 20. PMID: 20642382
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Substances : Arginine, Testosterone
Diseases : Drug-Induced Toxicity , Estrogen Toxicity, Polycystic Ovary Syndrome
Pharmacological Actions : Antihypertensive Agents
Additional Keywords : Sex Hormone-Binding Globulin
[+]

Licorice reduces serum testosterone in healthy women. Oct 01, 2004

Pubmed Data : Steroids. 2004 Oct-Nov;69(11-12):763-6. PMID: 15579328
Article Published Date : Oct 01, 2004
Study Type : Human Study
Additional Links
Substances : Licorice
Diseases : Hirsutism, Polycystic Ovary Syndrome, Testosterone: Too High
[+]

Licorice reduces the side effects of spironolactone in the treatment of polycystic ovary syndrome. Mar 01, 2007

Pubmed Data : Eur J Obstet Gynecol Reprod Biol. 2007 Mar;131(1):61-7. Epub 2006 Nov 17. PMID: 17113210
Article Published Date : Mar 01, 2007
Study Type : Human Study
Additional Links
Substances : Licorice
Diseases : Polycystic Ovary Syndrome
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Low intakes of dietary fiber and magnesium are associated with insulin resistance and hyperandrogenism in polycystic ovary syndrome.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2019 Apr ;7(4):1426-1437. Epub 2019 Feb 27. PMID: 31024716
Article Published Date : Mar 31, 2019
Study Type : Human Study
Additional Links
Substances : Magnesium Sulfate
Diseases : Hyperandrogenemia, Insulin Resistance, Polycystic Ovary Syndrome
[+]

Magnesium and zinc co-supplementation for 12 weeks among women with PCOS had beneficial effects on inflammation and oxidative stress. Nov 09, 2017

Pubmed Data : Biol Trace Elem Res. 2017 Nov 10. Epub 2017 Nov 10. PMID: 29127547
Article Published Date : Nov 09, 2017
Study Type : Human Study
Additional Links
Substances : Magnesium, Zinc
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Magnesium-zinc-calcium-vitamin D supplementation in patients with PCOS had beneficial effects on insulin metabolism and markers of cardio-metabolic risk.Sep 30, 2017

Pubmed Data : Arch Iran Med. 2017 Oct ;20(10):640-645. PMID: 29137465
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Substances : Calcium, Magnesium, Vitamin D, Zinc
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Additional Keywords : Risk Reduction
[+]

Myo-inositol decreases circulating insulin and serum testosterone as well as improvement in metabolic factors in women with polycystic ovary syndrome. Mar 01, 2009

Pubmed Data : Eur Rev Med Pharmacol Sci. 2009 Mar-Apr;13(2):105-10. PMID: 19499845
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Inositol
Diseases : Polycystic Ovary Syndrome
[+]

Myo-inositol plus folic acid has a beneficial effect in improving ovarian function in women with oligomenorrhea and polycystic ovaries. Sep 01, 2007

Pubmed Data : Eur Rev Med Pharmacol Sci. 2007 Sep-Oct;11(5):347-54. PMID: 18074942
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Folic Acid , Myo-inositol
Diseases : Oligomenorrhea, Polycystic Ovary Syndrome
[+]

Myo-inositol was useful in PCOS women in lowering BMI and ameliorating insulin sensitivity, and improving menstrual cycle.Dec 31, 2016

Pubmed Data : Gynecol Endocrinol. 2017 Jan ;33(1):39-42. Epub 2016 Nov 3. PMID: 27808588
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Myo-inositol
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Pharmacological Actions : Hypoglycemic Agents
[+]

NAC can be used as a substitute for insulin-sensitizing agent in treatment of polycystic ovarian syndrome.Jan 31, 2019

Pubmed Data : J Obstet Gynaecol India. 2019 Feb ;69(1):77-81. Epub 2018 May 28. PMID: 30814814
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Insulin Sensitizers
Additional Keywords : Superiority of Natural Substances versus Drugs
Problem Substances : Metformin
[+]

NAC improves oocyte and embryo quality and could be administered as an alternative to metformin.Mar 31, 2016

Pubmed Data : Reprod Fertil Dev. 2016 Apr ;28(6):723-31. PMID: 25482371
Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
[+]

Octylphenol may play a role in insulin resistance in PCOS patients.Oct 01, 2011

Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct ;31(10):1753-6. PMID: 22027783
Article Published Date : Oct 01, 2011
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Problem Substances : Octylphenol
[+]

Omega-3 fatty acids supplementation for 12 weeks in PCOS women significantly improved gene expression of PPAR-γ and LDLR.Feb 23, 2017

Pubmed Data : Horm Metab Res. 2017 Feb 24. Epub 2017 Feb 24. PMID: 28235206
Article Published Date : Feb 23, 2017
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Polycystic Ovary Syndrome
Additional Keywords : Gene Expression Regulation
[+]

Oral administration of chamomile capsule caused a significant decrease in total testosterone in patients with polycystic ovary syndrome.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Res Med Sci. 2018 ;23:33. Epub 2018 Apr 26. PMID: 29887901
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Chamomile
Diseases : Polycystic Ovary Syndrome
[+]

Organochlorine pesticides levels may play a role in the pathogenesis of polycystic ovary syndrome by affecting hormones levels.Feb 28, 2017

Pubmed Data : Chemosphere. 2017 Mar ;171:595-600. Epub 2016 Dec 26. PMID: 28043072
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Diseases : Pesticide Toxicity , Polycystic Ovary Syndrome
Additional Keywords : Risk Factors
Problem Substances : Organochlorine pesticides, Pesticides
[+]

PCOS women are considered as a high-risk population for prediabetes.Sep 19, 2016

Pubmed Data : Bosn J Basic Med Sci. 2016 Sep 20. Epub 2016 Sep 20. PMID: 27648989
Article Published Date : Sep 19, 2016
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome, Prediabetes
Additional Keywords : Risk Factors
[+]

Progesterone resistance may play a role in polycystic ovary syndromeJun 01, 2011

Pubmed Data : J Clin Endocrinol Metab. 2011 Jun ;96(6):1737-46. Epub 2011 Mar 16. PMID: 21411543
Article Published Date : Jun 01, 2011
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome, Progesterone Resistance
[+]

Raw red onion consumption appears to be effective as a cholesterol-lowering food agent in women with polycystic ovary syndrome.Mar 31, 2014

Pubmed Data : J Obstet Gynaecol Res. 2014 Apr ;40(4):1067-76. Epub 2014 Mar 10. PMID: 24612081
Article Published Date : Mar 31, 2014
Study Type : Human Study
Additional Links
Substances : Onion
Diseases : High Cholesterol, Obesity, Polycystic Ovary Syndrome
Pharmacological Actions : Anticholesteremic Agents
[+]

Regular mindful yoga practice can be a useful complementary therapeutic option for women with polycystic ovary syndrome.Apr 13, 2020

Pubmed Data : J Am Osteopath Assoc. 2020 Apr 14. Epub 2020 Apr 14. PMID: 32285088
Article Published Date : Apr 13, 2020
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Yoga
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Resveratrol may improve some outcomes of PCOS patients.Jul 20, 2019

Pubmed Data : J Assist Reprod Genet. 2019 Jul 21. Epub 2019 Jul 21. PMID: 31327131
Article Published Date : Jul 20, 2019
Study Type : Human Study
Additional Links
Substances : Resveratrol
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Hypoxia-inducible factor-1 (HIF-1) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Resveratrol significantly reduced ovarian and adrenal androgens.Oct 17, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Endocrinol Metab. 2016 Oct 18:jc20161858. Epub 2016 Aug 18. PMID: 27754722
Article Published Date : Oct 17, 2016
Study Type : Human Study
Additional Links
Substances : Resveratrol
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Androgen
Additional Keywords : Significant Treatment Outcome
[+]

Selenium supplementation for 8 weeks among PCOS women had beneficial effects on reproductive outcomes, DHEA, hs-CRP, and MDA levels.Aug 11, 2015

Pubmed Data : Horm Metab Res. 2015 Aug 12. Epub 2015 Aug 12. PMID: 26267328
Article Published Date : Aug 11, 2015
Study Type : Human Study
Additional Links
Substances : Selenium
Diseases : C-Reactive Protein, Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Malondialdehyde Down-regulation
[+]

Serum vitamin D levels are correlated with metabolic risk factors in women with PCOS.Jan 01, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2020 ;11:171. Epub 2020 Mar 31. PMID: 32296394
Article Published Date : Jan 01, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Polycystic Ovary Syndrome
[+]

Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome. Jul 07, 2009

Pubmed Data : Phytother Res. 2009 Jul 7. PMID: 19585478
Article Published Date : Jul 07, 2009
Study Type : Human Study
Additional Links
Substances : Spearmint
Diseases : Hirsutism, Polycystic Ovary Syndrome, Testosterone: Too High
Pharmacological Actions : Androgen Antagonists
[+]

Taking myo-inositol by women with PCOS had beneficial effects on glycemic control, triglycerides and VLDL-cholesterol levels, and gene expression of PPAR-γ.Jan 03, 2019

Pubmed Data : Gynecol Endocrinol. 2019 Jan 4:1-6. Epub 2019 Jan 4. PMID: 30608001
Article Published Date : Jan 03, 2019
Study Type : Human Study
Additional Links
Substances : Myo-inositol
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Gene Expression Regulation, Superiority of Natural Substances versus Drugs
[+]

The beneficial effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome.Jan 23, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2020 Jan 24 ;19(1):8. Epub 2020 Jan 24. PMID: 31980022
Article Published Date : Jan 23, 2020
Study Type : Human Study
Additional Links
Substances : Flaxseed
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Insulin Sensitizers, Interleukin-6 Downregulation
[+]

The Chinese herbal formula "tiangui fang" may have value in the treatment of hyperandrogenism and hyperinsulinism in polycystic ovary syndrome.Aug 01, 2000

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Aug ;20(8):589-92. PMID: 11789189
Article Published Date : Aug 01, 2000
Study Type : Human Study
Additional Links
Substances : Chinese Herbal Formula: Tiangui Fang
Diseases : Adrenal Hyperandrogenism, Hyperinsulinism, Polycystic Ovary Syndrome
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Drug: Metformin
[+]

The Chinese herbal formula Jinqi Jiangtang has beneficial effects in women with polycystic ovary syndrome (PCOS). Nov 01, 2006

Pubmed Data : Zhong Xi Yi Jie He Xue Bao. 2006 Nov;4(6):579-84. PMID: 17090371
Article Published Date : Nov 01, 2006
Study Type : Human Study
Additional Links
Substances : Chinense Herbal Formula: Jinqi Jiangtang
Diseases : Polycystic Ovary Syndrome
[+]

The combined therapy of acupuncture, herbal medicine and clomiphene improves the pregnancy rate and reduces early abortion rate in patients. Jan 31, 2015

Pubmed Data : Zhongguo Zhen Jiu. 2015 Feb ;35(2):114-8. PMID: 25854013
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Diseases : Infertility: Female, Polycystic Ovary Syndrome
Therapeutic Actions : Acupuncture, Integrative Medicine, Moxibustion
Pharmacological Actions : Fertility Agents: Female
Additional Keywords : Herbal Medicine, Plant Extracts, Significant Treatment Outcome
[+]

The compound found in buckwheat known as d-chiro-inositol have a therapeutic effect in polycystic ovary syndrome.Apr 29, 1999

Pubmed Data : N Engl J Med. 1999 Apr 29;340(17):1314-20. PMID: 10219066
Article Published Date : Apr 29, 1999
Study Type : Human Study
Additional Links
Substances : Buckwheat, D-Chiro-Inositol, Inositol
Diseases : Polycystic Ovary Syndrome
[+]

The effect of concentrated pomegranate juice consumption on risk factors of cardiovascular diseases in women with polycystic ovary syndrome.Aug 06, 2020

Pubmed Data : Phytother Res. 2020 Aug 7. Epub 2020 Aug 7. PMID: 32767710
Article Published Date : Aug 06, 2020
Study Type : Human Study
Additional Links
Substances : Pomegranate
Diseases : Cardiovascular Diseases, Polycystic Ovary Syndrome
Pharmacological Actions : Antihypertensive Agents
[+]

The study concluded that there was a beneficial effect of vitamin D supplementation on ovulatory dysfunctions and blood pressure.Sep 30, 2017

Pubmed Data : J Obstet Gynaecol India. 2017 Oct ;67(5):349-355. Epub 2017 May 26. PMID: 28867886
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Polycystic Ovary Syndrome, Vitamin D Deficiency
Pharmacological Actions : Insulin Sensitizers
[+]

There is a high prevalence of biochemical hyperandrogenism in patients with PCOS.Nov 01, 2010

Pubmed Data : Rev Bras Ginecol Obstet. 2010 Nov ;32(11):541-8. PMID: 21271165
Article Published Date : Nov 01, 2010
Study Type : Human Study
Additional Links
Diseases : Adrenal Hyperandrogenism, Polycystic Ovary Syndrome
Additional Keywords : Diseases that are Linked
[+]

There was a significant decrease in the serum anti-Mullerian hormone level after administration of cinnamon.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Hum Reprod Sci. 2017 Jan-Mar;10(1):31-36. PMID: 28479753
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Cinnamon
Diseases : Polycystic Ovary Syndrome
Additional Keywords : cinnamon, Metformin, Polycystic Ovary Syndrome
Problem Substances : Metformin
[+]

These findings suggest the possibility of vinegar to restore ovulatory function through improving insulin sensitivity in PCOS patients.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Tohoku J Exp Med. 2013 ;230(1):17-23. PMID: 23666047
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Vinegar
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
[+]

These observations confirm the potential role of BPA in polycystic ovary syndrome pathophysiology.Sep 09, 2016

Pubmed Data : Environ Sci Pollut Res Int. 2016 Sep 10. Epub 2016 Sep 10. PMID: 27614642
Article Published Date : Sep 09, 2016
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
[+]

These results point to the potential role of BPA in the pathogenesis of the ovarian hyperandrogenism in women with PCOS.Sep 24, 2018

Pubmed Data : Reprod Toxicol. 2018 Sep 25. Epub 2018 Sep 25. PMID: 30266220
Article Published Date : Sep 24, 2018
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome
Problem Substances : Bisphenol A
[+]

This study is the first to demonstrate that acupuncture reduces serum anti-Müllerian hormone levels and ovarian volume.Feb 28, 2015

Pubmed Data : Acta Obstet Gynecol Scand. 2015 Mar ;94(3):279-87. Epub 2015 Jan 28. PMID: 25545309
Article Published Date : Feb 28, 2015
Study Type : Human Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Acupuncture
[+]

Treatment with d-chiro-inositol and alpha lipoic acid in the management of polycystic ovary syndrome.May 31, 2019

Pubmed Data : Gynecol Endocrinol. 2019 Jun ;35(6):506-510. Epub 2019 Jan 7. PMID: 30612488
Article Published Date : May 31, 2019
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid, D-Chiro-Inositol
Diseases : Polycystic Ovary Syndrome
[+]

Vitamin D Decreases Serum VEGF Correlating with Clinical Improvement in Vitamin D-Deficient Women with polycystic ovary syndrome.Mar 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Mar 28 ;9(4). Epub 2017 Mar 28. PMID: 28350328
Article Published Date : Mar 27, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors
[+]

Vitamin D is associated with insulin resistance in women with polycystic ovary syndrome.Dec 31, 2015

Pubmed Data : Mol Nutr Food Res. 2016 Jan ;60(1):110-8. Epub 2015 Sep 7. PMID: 26255991
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Insulin Resistance, Polycystic Ovary Syndrome, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Walnuts and almonds may improve metabolic and endocrine parameters in PCOS.Mar 01, 2011

Pubmed Data : Eur J Clin Nutr. 2011 Mar ;65(3):386-93. Epub 2010 Dec 15. PMID: 21157477
Article Published Date : Mar 01, 2011
Study Type : Human Study
Additional Links
Substances : Almond, Omega-3 Fatty Acids, Walnut
Diseases : Hyperglycemia, Inflammation, Insulin Resistance, Polycystic Ovary Syndrome
Pharmacological Actions : Insulin Sensitizers
[+]

Increased BPA concentration in the follicular fluid of polycystic ovary syndrome patients may play an important role in its pathogenesis.Dec 31, 2016

Pubmed Data : Gynecol Endocrinol. 2017 Jan ;33(1):21-25. Epub 2016 May 17. PMID: 27187585
Article Published Date : Dec 31, 2016
Study Type : Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Polycystic Ovary Syndrome
Problem Substances : Bisphenol A
[+]

The present study show the beneficial effects of marjoram tea on the hormonal profile of polycystic ovary syndrome.Jan 31, 2016

Pubmed Data : J Hum Nutr Diet. 2016 Feb ;29(1):105-11. Epub 2015 Feb 9. PMID: 25662759
Article Published Date : Jan 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Marjoram
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Pharmacological Actions : Insulin Sensitizers
[+]

The effect of flaxseed supplementation on hormonal levels associated with polycystic ovarian syndrome.Dec 31, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Top Nutraceutical Res. 2007 ;5(4):177-181. PMID: 19789727
Article Published Date : Dec 31, 2006
Study Type : Human: Case Report
Additional Links
Substances : Flaxseed
Diseases : Polycystic Ovary Syndrome, Testosterone: Too High
[+]

Berberine ameliorates prenatal dihydrotestosterone exposure-induced autism-like behaviour by suppression of androgen receptor.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Neurosci. 2020 ;14:87. Epub 2020 Apr 9. PMID: 32327976
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Autism, Fetal Origin of Adult Disease, Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants
Additional Keywords : Risk Reduction
[+]

Berberine decreases insulin resistance in a polycystic ovarian syndrome model.Nov 24, 2019

Pubmed Data : Regul Toxicol Pharmacol. 2019 Nov 25:104544. Epub 2019 Nov 25. PMID: 31778716
Article Published Date : Nov 24, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Pharmacological Actions : Insulin Sensitizers
[+]

Brown adipose tissue activation by rutin ameliorates polycystic ovary syndrome.Apr 21, 2017

Pubmed Data : J Nutr Biochem. 2017 Apr 22 ;47:21-28. Epub 2017 Apr 22. PMID: 28501702
Article Published Date : Apr 21, 2017
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Polycystic Ovary Syndrome
[+]

Cinnamon improves metabolic factors without detectable effects on adiponectin in women with polycystic ovary syndrome.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asia Pac J Clin Nutr. 2018;27(3):556-563. PMID: 29737802
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cinnamon
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

Cinnamon supplementation improves insulin resistance and may be a potential therapeutic agent for the treatment of PCOS.Oct 18, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Biol Endocrinol. 2018 Oct 19 ;16(1):99. Epub 2018 Oct 19. PMID: 30340496
Article Published Date : Oct 18, 2018
Study Type : Animal Study
Additional Links
Substances : Cinnamon
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Pharmacological Actions : Insulin Sensitizers
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Composition of royal jelly and its anti-androgenic effect on reproductive parameters in a polycystic ovarian syndrome.Jun 06, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Jun 7 ;9(6). Epub 2020 Jun 7. PMID: 32517356
Article Published Date : Jun 06, 2020
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants
[+]

Curcumin may be considered as protective factor against inflammatory state of PCOS.Sep 30, 2017

Pubmed Data : Cell J. 2017 Oct ;19(3):425-433. Epub 2017 Aug 19. PMID: 28836404
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Insulin Sensitizers, Interleukin-6 Downregulation
[+]

Effects of vitamin D deficiency on proliferation and autophagy of ovarian and liver tissues in a model of polycystic ovary syndrome.Sep 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2019 Sep 10 ;9(9). Epub 2019 Sep 10. PMID: 31509973
Article Published Date : Sep 09, 2019
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Polycystic Ovary Syndrome, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Electroacupuncture alleviates polycystic ovary syndrome-like symptoms.Jul 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med. 2020 Jul 22 ;26(1):73. Epub 2020 Jul 22. PMID: 32698821
Article Published Date : Jul 21, 2020
Study Type : Animal Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Autophagy Up-regulation
[+]

Grape seed extract could reduce the effects of dyslipidemia and inflammation in polycystic ovary syndrome.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Fertil Steril. 2017 Oct ;11(3):176-183. Epub 2017 Aug 27. PMID: 28868839
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypolipidemic, Interleukin-6 Downregulation
[+]

Gut microbiota-bile acid-interleukin-22 axis orchestrates polycystic ovary syndrome.Jul 21, 2019

Pubmed Data : Nat Med. 2019 Jul 22. Epub 2019 Jul 22. PMID: 31332392
Article Published Date : Jul 21, 2019
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Polycystic Ovary Syndrome
[+]

Hydroalcoholic extract of flaxseed improves polycystic ovary syndrome in a rat model.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2018 Jun ;21(6):645-650. PMID: 29942457
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Flaxseed
Diseases : Polycystic Ovary Syndrome, Testosterone: Too High
[+]

Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.Mar 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Toxicol. 2013 Apr ;36:104-16. Epub 2013 Jan 25. PMID: 23453003
Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Hair Loss, Infertility: Male, Obesity, Polycystic Ovary Syndrome
Additional Keywords : DNA Methylation, Increased Risk, Transgenerational inheritance
Problem Substances : Hydrocarbons, Jet fuel
[+]

Korean red ginseng counteracts steroid-induced polycystic ovary in the mouse model. Mar 01, 2009

Pubmed Data : Arch Pharm Res. 2009 Mar;32(3):347-52. Epub 2009 Apr 23. PMID: 19387577
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Polycystic Ovary Syndrome
[+]

Korean red ginseng may play an ameliorative role in rat infertility induced by polycystic ovary syndrome. Oct 01, 2005

Pubmed Data : Fertil Steril. 2005 Oct;84 Suppl 2:1139-43. PMID: 16210005
Article Published Date : Oct 01, 2005
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Infertility: Female, Polycystic Ovary Syndrome
[+]

Linagliptin and indole-3-carbinol combination might represent a beneficial therapeutic modality for amelioration of polycystic ovarian syndrome.Jul 31, 2017

Pubmed Data : Chem Biol Interact. 2017 Aug 1 ;273:190-199. Epub 2017 Jun 13. PMID: 28619389
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-10 downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Matricaria chamomilla extract ameliorated hypothyroidism associated with polycystic ovary syndrome.Jan 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2020 Jan 5 ;10(1). Epub 2020 Jan 5. PMID: 31948119
Article Published Date : Jan 04, 2020
Study Type : Animal Study
Additional Links
Substances : Chamomile
Diseases : Hypothyroidism, Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants
[+]

Microbiota interventions through FMT and Lactobacillus transplantation were beneficial for the treatments of PCOS rats.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(4):e0153196. Epub 2016 Apr 19. PMID: 27093642
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Lactobacillus probiotics
Diseases : Dysbiosis, Polycystic Ovary Syndrome
Additional Keywords : Microbiota
[+]

Moringa oleifera could lowering the blood insulin levels, subsequently decreasing the androgen thus allowed the increasing of folliculogenesis in PCOS.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Immunol Endocr Metab Agents Med Chem. 2018 May ;18(1):22-30. PMID: 30369967
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Insulin Down-Regulation
[+]

Naringenin treatment demonstrated antioxidant and steroidogenic enzyme activity in a model of polycystic ovary syndrome.Jan 12, 2019

Pubmed Data : Med Sci Monit. 2019 Jan 13 ;25:395-401. Epub 2019 Jan 13. PMID: 30636259
Article Published Date : Jan 12, 2019
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants
[+]

Ocimum kilimandscharicum L. restores ovarian functions in letrozole-induced polycystic ovary syndrome.Jul 07, 2019

Pubmed Data : Life Sci. 2019 Jul 8:116640. Epub 2019 Jul 8. PMID: 31295470
Article Published Date : Jul 07, 2019
Study Type : Animal Study
Additional Links
Substances : African Basil
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Insulin Sensitizers
Problem Substances : Letrozole (trade name Femera)
[+]

Photobiomodulation can improve ovarian activity in polycystic ovary syndrome-induced rats.Apr 30, 2019

Pubmed Data : J Photochem Photobiol B. 2019 May ;194:6-13. Epub 2019 Mar 12. PMID: 30897401
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Laser Treatment: Low-Level
[+]

Quercetin alleviated dehydroepiandrosterone-induced polycystic ovarian syndrome.Mar 10, 2020

Pubmed Data : J Basic Clin Physiol Pharmacol. 2020 Mar 11. Epub 2020 Mar 11. PMID: 32160160
Article Published Date : Mar 10, 2020
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants
[+]

Sage tea consumption may influence the oxidative status and reduce the blood glucose and atherogenic index in PCOS women.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2020 May-Jun;10(3):263-272. PMID: 32523881
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Oxidative Stress, Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
[+]

Spearmint has treatment potential on PCOS through inhibition of testosterone and restoration of follicular development in ovarian tissue.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharm Bull. 2017 Dec ;7(4):651-654. Epub 2017 Dec 31. PMID: 29399556
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Spearmint
Diseases : Polycystic Ovary Syndrome
Additional Keywords : Essential Oils
[+]

T. occidentalis essential oil and its active component, α-thujone, can be used for the treatment of PCOS without inducing osteoporosis.Jun 19, 2015

Pubmed Data : J Ethnopharmacol. 2015 Jun 20 ;168:25-30. Epub 2015 Mar 27. PMID: 25818694
Article Published Date : Jun 19, 2015
Study Type : Animal Study
Additional Links
Substances : Thujae occidentalis
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Phytotherapy
[+]

Tanshinone IIA attenuates estradiol-induced polycystic ovarian syndrome.Apr 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 May ;17(5):3501-3508. Epub 2019 Mar 6. PMID: 30988730
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Polycystic Ovary Syndrome
[+]

The present study provides in vivo evidence that crocetin improved the polycystic ovarian syndrome in mice.Oct 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:1363-1369. Epub 2018 Aug 31. PMID: 30257351
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Crocetin
Diseases : Polycystic Ovary Syndrome
[+]

The regulatory effect of genistein on granulosa cell in ovary of rat with polycystic ovarian syndrome.Aug 29, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Vet Med Sci. 2018 Aug 30 ;80(8):1348-1355. Epub 2018 Jun 22. PMID: 29937456
Article Published Date : Aug 29, 2018
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Apoptotic
[+]

Therapeutic effect of Ecklonia cava extract in letrozole-induced polycystic ovary syndrome.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1325. Epub 2018 Nov 19. PMID: 30524282
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Seaweed: Brown
Diseases : Polycystic Ovary Syndrome
[+]

This study has shown that ascorbic acid and alpha-tocopherol are beneficial in the therapy of polycystic ovary syndrome.Jul 27, 2020

Pubmed Data : Reprod Sci. 2020 Jul 28. Epub 2020 Jul 28. PMID: 32725591
Article Published Date : Jul 27, 2020
Study Type : Animal Study
Additional Links
Substances : Vitamin C, Vitamin E: alpha tocopherol
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants
[+]

This study provides evidence for the potential ameliorative effects of rutin against clinical and biochemical features of PCOS.Dec 06, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ovarian Res. 2016 Dec 7 ;9(1):86. Epub 2016 Dec 7. PMID: 27923406
Article Published Date : Dec 06, 2016
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Androgen
[+]

Thymoquinone ameliorates some endocrine parameters and histological alteration in a rat model of polycystic ovary syndrome.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Reprod Biomed (Yazd). 2018 Apr ;16(4):275-284. PMID: 29942936
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Polycystic Ovary Syndrome
[+]

Thymoquinone induced significant restoration of normal physio-molecular behaviour of ovary.Oct 28, 2015

Pubmed Data : Pharm Biol. 2015 Oct 29:1-12. Epub 2015 Oct 29. PMID: 26510692
Article Published Date : Oct 28, 2015
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : NF-kappaB Inhibitor
[+]

Thymoquinone may enhance the developmental competence of polycystic ovary syndrome oocytes.Jun 16, 2019

Pubmed Data : Mol Reprod Dev. 2019 Jun 17. Epub 2019 Jun 17. PMID: 31209968
Article Published Date : Jun 16, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants
Additional Keywords : Epigenetic Modification
[+]

Tribulus terrestris may provide an alternative treatment for ovarian cysts. Aug 24, 2011

Pubmed Data : Reprod Domest Anim. 2011 Aug 24. Epub 2011 Aug 24. PMID: 21883512
Article Published Date : Aug 24, 2011
Study Type : Animal Study
Additional Links
Substances : Tribulus
Diseases : Ovarian Cysts, Polycystic Ovary Syndrome
[+]

Vitamin C suppresses ovarian pathophysiology in experimental polycystic ovarian syndrome.Sep 18, 2019

Pubmed Data : Pathophysiology. 2019 Sep 19. Epub 2019 Sep 19. PMID: 31564389
Article Published Date : Sep 18, 2019
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants
[+]

Welsh onion root restores ovarian functions from letrozole induced-polycystic ovary syndrome.Oct 03, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Oct 4 ;10(10). Epub 2018 Oct 4. PMID: 30287740
Article Published Date : Oct 03, 2018
Study Type : Animal Study
Additional Links
Substances : Onion
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Aromatase Inhibitors
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Bisphenol-A and polycystic ovary syndrome: a review of the literature.Jul 13, 2020

Pubmed Data : Rev Environ Health. 2020 Jul 14. Epub 2020 Jul 14. PMID: 32663175
Article Published Date : Jul 13, 2020
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome
Problem Substances : Bisphenol A
[+]

A mother's exposure to BPA during pregnancy may also lead to the development of PCOS in the female offspring.Mar 31, 2014

Pubmed Data : Gynecol Endocrinol. 2014 Apr ;30(4):260-5. Epub 2014 Jan 7. PMID: 24397396
Article Published Date : Mar 31, 2014
Study Type : Review
Additional Links
Diseases : Polycystic Ovary Syndrome
Additional Keywords : Prenatal Epigenetic Programming, Risk Factors
Problem Substances : Bisphenol A
[+]

Acupuncture may improve menstrual health and coping among women experiencing delays in becoming pregnant.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Womens Health. 2014 ;6:313-25. Epub 2014 Mar 17. PMID: 24669195
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Dysmenorrhea, Female Reproductive Development Abnormalities, Infertility: Female, Polycystic Ovary Syndrome, Premenstrual syndrome
Therapeutic Actions : Acupuncture
[+]

Berberine and puerarin lower the degree of insulin resistance and the androgen synthesis in procine ovarian thecal cells, indicating their potential value in the treatment of polycystic syndrome. Jul 01, 2009

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Jul;29(7):623-7. PMID: 19852296
Article Published Date : Jul 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Berberine, Puerarin
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
[+]

Distribution and laws of TCM syndrome patterns in patients with PCOS.Feb 28, 2011

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 Mar ;31(3):323-6. PMID: 21485070
Article Published Date : Feb 28, 2011
Study Type : Review
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Acupuncture
[+]

Fasting regimens can reduce IGF-1, IGFBP1, glucose and insulin levels and consequently have beneficial effects on ovarian function.Jul 31, 2017

Pubmed Data : Med Hypotheses. 2017 Aug ;105:1-3. Epub 2017 Jun 23. PMID: 28735644
Article Published Date : Jul 31, 2017
Study Type : Review
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Inositol as putative integrative treatment for polycystic ovary syndrome.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Biomed Online. 2016 Dec ;33(6):770-780. Epub 2016 Sep 16. PMID: 27717596
Article Published Date : Nov 30, 2016
Study Type : Review
Additional Links
Substances : Inositol
Diseases : Insulin Resistance, Obesity, Polycystic Ovary Syndrome
Pharmacological Actions : Insulin Sensitizers
[+]

Insulin resistance directly exaggerates the androgenic potential within theca cells, suggesting the possible involvement of this ovarian metabolic phenotype in polycystic ovary syndrome hyperandrogenism.May 01, 2009

Pubmed Data : Fertil Steril. 2009 May;91(5 Suppl):1990-7. Epub 2008 Jul 30. PMID: 18672234
Article Published Date : May 01, 2009
Study Type : In Vitro Study
Additional Links
Diseases : Insulin Resistance, Polycystic Ovary Syndrome
Additional Keywords : Diseases that are Linked
[+]

N-3 fatty acids as preventive and therapeutic agents in attenuating PCOS complications.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EXCLI J. 2019 ;18:558-575. Epub 2019 Jul 25. PMID: 31611740
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Polyunsaturated Fatty Acids (PUFAs)
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Hypolipidemic
[+]

Natural substances such as Aloe vera, cinnamon, green tea, fenugreek, and silymarin can be used as a new supportive care for PCOS.Mar 26, 2020

Pubmed Data : Biomol Concepts. 2020 Mar 26 ;11(1):57-75. Epub 2020 Mar 26. PMID: 32229652
Article Published Date : Mar 26, 2020
Study Type : Review
Additional Links
Substances : Aloe Vera, Cinnamon, Fenugreek, Green Tea, Silymarin
Diseases : Polycystic Ovary Syndrome
[+]

Paeoniflorin extract reverses dexamethasone-induced testosterone over-secretion.Jan 29, 2019

Pubmed Data : J Ethnopharmacol. 2019 Jan 30 ;229:97-103. Epub 2018 Sep 5. PMID: 30195059
Article Published Date : Jan 29, 2019
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Polycystic Ovary Syndrome, Testosterone: Too High
Problem Substances : Dexamethasone
[+]

Polycystic ovary syndrome management: a review of the possible amazing role of berberine.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Gynecol Obstet. 2020 Jan ;301(1):53-60. Epub 2020 Feb 14. PMID: 32060683
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Berberine
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Hypolipidemic
[+]

Quercetin and polycystic ovary syndrome, current evidence and future directions: a systematic reviewJan 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ovarian Res. 2020 Jan 31 ;13(1):11. Epub 2020 Jan 31. PMID: 32005271
Article Published Date : Jan 30, 2020
Study Type : Review
Additional Links
Substances : Quercetin
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Hypolipidemic
[+]

resveratrol emerges as a potential therapeutic agent to treat conditions associated with androgen excess, such as PCOS.Jul 31, 2015

Pubmed Data : Ann N Y Acad Sci. 2015 Aug ;1348(1):86-96. PMID: 26315293
Article Published Date : Jul 31, 2015
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Ovarian Diseases, Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Androgen
[+]

Resveratrol may have a therapeutic role to play in polycystic ovary syndrome. Jan 12, 2010

Pubmed Data : Mol Hum Reprod. 2010 Jan 12. Epub 2010 Jan 12. PMID: 20067985
Article Published Date : Jan 12, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Apoptotic
[+]

Resveratrol treatment in patients with polycystic ovary syndrome decreased pro-inflammatory and endoplasmic reticulum stress markers.Sep 03, 2019

Pubmed Data : Am J Reprod Immunol. 2019 Sep 4:e13186. Epub 2019 Sep 4. PMID: 31483910
Article Published Date : Sep 03, 2019
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The aim of this review is to examine the role of chronic inflammation and the sympathetic nervous system in the development of obesity and PCOS.Jun 30, 2015

Pubmed Data : Semin Reprod Med. 2015 Jul ;33(4):257-69. Epub 2015 Jul 1. PMID: 26132930
Article Published Date : Jun 30, 2015
Study Type : Review
Additional Links
Diseases : Inflammation, Polycystic Ovary Syndrome
Additional Keywords : Risk Factors
[+]

This review highlights that high dietary AGEs intake promotes deteriorating biological effects in women with PCOS.Jul 12, 2016

Pubmed Data : Curr Pharm Des. 2016 Jul 13. Epub 2016 Jul 13. PMID: 27412301
Article Published Date : Jul 12, 2016
Study Type : Review
Additional Links
Diseases : Advanced Glycation End products (AGE), Polycystic Ovary Syndrome
Additional Keywords : Risk Factors
[+]

This summarizes the role of dietary AGEs as mediators of metabolic and reproductive alterations in PCOS.Dec 03, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 Dec 4 ;7(12):10129-44. Epub 2015 Dec 4. PMID: 26690206
Article Published Date : Dec 03, 2015
Study Type : Review
Additional Links
Diseases : Advanced Glycation End products (AGE), Polycystic Ovary Syndrome
Additional Keywords : Risk Factors

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