Polymyalgia Rheumatica

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3 Substances Researched for Polymyalgia Rheumatica
NameACCKFocus
DHEA (Dehydroepiandrosterone)110Locked
Folic Acid 110Locked
Vitamin B-12110Locked
4 Problem Substances Researched for Polymyalgia Rheumatica
NameACCKFocus
Statin Drugs213Locked
Arimidex110Locked
Aromatase Inhibitor Drugs110Locked
Letrozole (trade name Femera)110Locked
1 Therapeutic Actions Researched for Polymyalgia Rheumatica
NameACCKFocus
Fasting/Caloric Restriction110Locked

View the Evidence:
8 Abstracts with Polymyalgia Rheumatica Research

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Active polymyalgia rheumatica is characterized by increased serum levels of Interleukin-6 probably originating in inflamed tissue. Mar 01, 2009

Pubmed Data : 1: Ann Rheum Dis. 2009 Mar 1. PMID:19254903
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Diseases : Polymyalgia Rheumatica
Pharmacological Actions : Interleukin-6 Downregulation
[+]

Due to the relatively low levels of DHEA found in patients with untreated polymyalgia rheumatica/giant cell arteritis, it may have therapeutic value in their treatment. Dec 01, 2010

Pubmed Data : J Endocrinol. 2010 Dec;207(3):319-28. Epub 2010 Sep 24. PMID: 16783861
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Giant Cell Arteritis, Polymyalgia Rheumatica
[+]

Elevated homocysteine levels associated with polymyalgia rheumatica and giant cell arteritis and the corticosteroid therapy used to treat these conditions may be attenuated with vitamin B12 and folic acid. Sep 01, 2003

Pubmed Data : Rheumatology (Oxford). 2003 Sep;42(9):1055-61. Epub 2003 Apr 16. PMID: 12730520
Article Published Date : Sep 01, 2003
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-12
Diseases : Corticosteroid-Induced Toxicity, Cortisone Toxicity , Giant Cell Arteritis, Hyperhomocysteinemia, Polymyalgia Rheumatica
[+]

Fasting may have therapeutic value in the treatment of polymyalgia rheumatica. Aug 01, 2007

Pubmed Data : Forsch Komplementmed. 2007 Aug;14(4):235-9. Epub 2007 Jul 20. PMID: 17848800
Article Published Date : Aug 01, 2007
Study Type : Human Study
Additional Links
Diseases : Polymyalgia Rheumatica
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Increased production of Interleukin-6 is a characteristic of patients with polymyalgia rheumatica and giant cell arteritis. Sep 01, 1993

Pubmed Data : Arthritis Rheum. 1993 Sep;36(9):1286-94. PMID: 8216422
Article Published Date : Sep 01, 1993
Study Type : Human Study
Additional Links
Diseases : Giant Cell Arteritis, Polymyalgia Rheumatica
Pharmacological Actions : Interleukin-6 Downregulation
[+]

Musculoskeletal complaints are exceedingly common (71.5%) in those receiving long-term (6 months or longer) aromatase inhibitor therapy.Feb 01, 2010

Pubmed Data : Breast Cancer Res Treat. 2010 Feb;120(1):127-34. Epub 2009 Dec 25. PMID: 20035381
Article Published Date : Feb 01, 2010
Study Type : Human Study
Additional Links
Diseases : Arthralgia, Arthritis, Breast Cancer, Drug-Induced Toxicity , Musculoskeletal Abnormalities, Myalgias, Polymyalgia Rheumatica, Tendinitis
Problem Substances : Arimidex, Aromatase Inhibitor Drugs, Letrozole (trade name Femera)
[+]

Statin-Associated Polymyalgia RheumaticaDec 31, 2011

Pubmed Data : PLoS One. 2012 ;7(7):e41289. Epub 2012 Jul 23. PMID: 22844450
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Diseases : Polymyalgia Rheumatica
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
[+]

Polymyalgia, hypersensitivity pneumonitis and other reactions have been reported in paitents taking statin drugs.Mar 01, 1999

Pubmed Data : Chest. 1999 Mar ;115(3):886-9. PMID: 10084510
Article Published Date : Mar 01, 1999
Study Type : Human: Case Report
Additional Links
Diseases : Hypersensitivity, Pneumonitis, Pneumonitis: Hypersensitivity Type, Polymyalgia Rheumatica, Statin-Induced Pathologies
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Myotoxicity

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