Polymyositis

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2 Substances Researched for Polymyositis

Name	AC	CK	Focus
Creatine	1	10
Vitamin E	1	1

5 Problem Substances Researched for Polymyositis

Name	AC	CK	Focus
Statin Drugs	3	14
Cholesterol Lowering Drugs	1	3
Pravastatin	1	3
Simvastatin	1	3
Proton-Pump Inhibitors	1	1

1 Therapeutic Actions Researched for Polymyositis

Name	AC	CK	Focus
Exercise	1	10

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

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9 Abstracts with Polymyositis Research

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[+]

Creatine supplements combined with home exercises improve functional performance without significant adverse effects in patients with polymyositis or dermatomyositis.May 15, 2007

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Pubmed Data : Arthritis Rheum. 2007 May 15;57(4):694-702. PMID: 17471547

Article Published Date : May 15, 2007

Study Type : Human Study

Additional Links

Substances : Creatine

Diseases : Dermatomyositis, Myopathies, Polymyositis

Therapeutic Actions : Exercise

[+]

Lupus erythematosus and other autoimmune diseases related to statin therapy have been reported. Jan 01, 2007

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Pubmed Data : J Eur Acad Dermatol Venereol. 2007 Jan ;21(1):17-24. PMID: 17207162

Article Published Date : Jan 01, 2007

Study Type : Human Study

Additional Links

Diseases : Autoimmune Diseases, Dermatomyositis, Lichen Planus, Lupus Erythematosus: Cutaneous, Polymyositis, Statin-Induced Pathologies

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Immunotoxic

[+]

Tobacco smoking was associated with clinical and autoantibody phenotypes in Caucasians.Feb 13, 2018

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Pubmed Data : Semin Arthritis Rheum. 2018 Feb 14. Epub 2018 Feb 14. PMID: 29703532

Article Published Date : Feb 13, 2018

Study Type : Human Study

Additional Links

Diseases : Dermatomyositis, Polymyositis, Smoking

Additional Keywords : Risk Factors

[+]

Polymyositis induced or associated with lipid-lowering drugs has been reported. Apr 01, 2004

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Pubmed Data : Rev Med Interne. 2004 Apr ;25(4):294-8. PMID: 15050796

Article Published Date : Apr 01, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Polymyositis, Statin-Induced Pathologies

Problem Substances : Cholesterol Lowering Drugs, Statin Drugs

[+]

Pravastatin-associated polymyositis has been reported. Jan 01, 2004

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Pubmed Data : Rinsho Shinkeigaku. 2004 Jan ;44(1):25-7. PMID: 15199734

Article Published Date : Jan 01, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Muscle Disorders, Polymyositis

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Pravastatin

Adverse Pharmacological Actions : Myotoxicity

[+]

Severe polymyositis with simvastatin use has been reported. Nov 16, 2003

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Pubmed Data : Rev Neurol. 2003 Nov 16-30;37(10):934-6. PMID: 14634922

Article Published Date : Nov 16, 2003

Study Type : Human: Case Report

Additional Links

Diseases : Polymyositis

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Simvastatin

[+]

Proton pump inhibitors may cause myopathy including polymyositis.Jun 01, 2006

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Pubmed Data : Eur J Clin Pharmacol. 2006 Jun;62(6):473-9. Epub 2006 Apr 22. PMID: 16758264

Article Published Date : Jun 01, 2006

Study Type : Review

Additional Links

Diseases : Myopathies, Polymyositis

Additional Keywords : Drug: Omeprazole

Problem Substances : Proton-Pump Inhibitors

[+]

Statin drugs are known in some cases to induce autoimmune myopathies such as dermatomyositis, polymyositis, and immune-mediated necrotizing myopathies (IMNM).Jun 01, 2011

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Pubmed Data : Nat Rev Neurol. 2011 Jun ;7(6):343-54. Epub 2011 Jun 8. PMID: 21654717

Article Published Date : Jun 01, 2011

Study Type : Review

Additional Links

Diseases : Dermatomyositis, Immune-Mediated Necrotizing Myopathies , Polymyositis, Statin-Induced Pathologies

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Immunotoxic

[+]

Vitamin E many inhibit initiation of the autoimmune diseases such as scleroderma, discoid lupus erythematosus, porphyria cutanea tarda, several types of vasculitis, and polymyositis.Mar 01, 1978

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Pubmed Data : Cutis. 1978 Mar;21(3):321-5. PMID: 343998

Article Published Date : Mar 01, 1978

Study Type : Commentary

Additional Links

Substances : Vitamin E

Diseases : Autoimmune Diseases, Polymyositis, Porphyrias, Scleroderma, Systemic Lupus Erythematosus, Vasculitis

Copyright: elenabsl / 123RF Stock Photo

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

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