Pre-Eclampsia

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33 Substances Researched for Pre-Eclampsia
NameACCKFocus
Vitamin C550Locked
Vitamin D642Locked
Calcium340Locked
Arginine432Locked
Chocolate230Locked
Folic Acid 220Locked
Omega-3 Fatty Acids220Locked
Vitamin E220Locked
Coenzyme Q10314Locked
Magnesium414Locked
B-complex110Locked
Chlorella (Algae)110Locked
Dates110Locked
Fiber110Locked
Fruit: All110Locked
Rhubarb110Locked
Selenium110Locked
Silibinin110Locked
Vegetables: All 110Locked
Vitamin B-12110Locked
Vitamin B-6110Locked
Astragaloside24Locked
Astaxanthin23Locked
Grape23Locked
Magnesium Sulfate23Locked
Gastrodin12Locked
Mangiferin12Locked
Olive Oil12Locked
Resveratrol22Locked
Vitexins12Locked
Antioxidant formulas11Locked
EGCG (Epigallocatechin gallate)11Locked
Paeoniflorin11Locked
4 Problem Substances Researched for Pre-Eclampsia
NameACCKFocus
Antidepressants110Locked
Bisphenol A 110Locked
Ferrous Sulphate110Locked
Industrial Iron110Locked
2 Therapeutic Actions Researched for Pre-Eclampsia
NameACCKFocus
Guided Imagery110Locked
Sunlight exposure11Locked
2 Problematic Actions Researched for Pre-Eclampsia
NameACCKFocus
Vaccination: All110Locked
Vaccination: Influenza110Locked

View the Evidence:
79 Abstracts with Pre-Eclampsia Research

[+]

Calcium supplementation appears to approximately halve the risk of pre-eclampsia, to reduce the risk of preterm birth and to reduce the rare occurrence of the composite outcome 'death or serious morbidity'. Jan 01, 2010

Pubmed Data : Cochrane Database Syst Rev. 2010(8):CD001059. Epub 2010 Aug 4. PMID: 20687064
Article Published Date : Jan 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : Calcium
Diseases : Hypertension, Ovarian Pregnancy, Pre-Eclampsia, Preterm Birth: Prevention
[+]

Chocolate consumption during pregnancy may reduce the likelihood of preeclampsia.May 01, 2008

Pubmed Data : Epidemiology. 2008 May;19(3):459-64. PMID: 18379424
Article Published Date : May 01, 2008
Study Type : Meta Analysis
Additional Links
Substances : Chocolate
Diseases : Pre-Eclampsia
[+]

There is a significant link between exposure to PM2.5 and hypertensive disorders in pregnancy.Nov 01, 2019

Pubmed Data : Sci Total Environ. 2019 Nov 2 ;703:134985. Epub 2019 Nov 2. PMID: 31731170
Article Published Date : Nov 01, 2019
Study Type : Meta Analysis
Additional Links
Diseases : Hypertension, Pre-Eclampsia, Pregnancy Complications
Additional Keywords : Increased Risk
[+]

A preparation of rhubarb reduces the risk for pregnancy induced hypertension. Jan 01, 2005

Pubmed Data : J Herb Pharmacother. 2005;5(4):1-11. PMID: 11783143
Article Published Date : Jan 01, 2005
Study Type : Human Study
Additional Links
Substances : Rhubarb
Diseases : Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia
[+]

Arginine supplements may improve foetal well-being and noenatal outcome in preeclempsia.Aug 01, 2006

Pubmed Data : Basic Clin Pharmacol Toxicol. 2006 Aug;99(2):146-52. PMID: 16918716
Article Published Date : Aug 01, 2006
Study Type : Human Study
Additional Links
Substances : Arginine
Diseases : Pre-Eclampsia
[+]

Calcium supplementation during pregnancy is associated with a reduction in risk of gestational hypertension, pre-eclampsia neonatal mortality and pre-term birth.Jan 01, 2011

Pubmed Data : BMC Public Health. 2011 ;11 Suppl 3:S18. Epub 2011 Apr 13. PMID: 21501435
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Calcium
Diseases : Gestational Hypertensive, Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia, Preterm Birth: Prevention
[+]

Calcium supplementation during pregnancy reduces the risk for gestational hypertension. Jan 01, 2002

Pubmed Data : Cochrane Database Syst Rev. 2002;(1):CD001059. PMID: 11869587
Article Published Date : Jan 01, 2002
Study Type : Human Study
Additional Links
Substances : Calcium
Diseases : Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia
[+]

Chlorella pyrenoidosa Supplementation Reduces the Risk of Anemia, Proteinuria and Edema in Pregnant Women.Mar 01, 2010

Pubmed Data : Plant Foods Hum Nutr. 2010 Mar;65(1):25-30. PMID: 20013055
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Anemia, Edema, Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia, Pregnancy Complications, Proteinuria
[+]

Chocolate intake during pregnancy may reduce the risks of preeclampsia and gestational hypertensionAug 01, 2010

Pubmed Data : Ann Epidemiol. 2010 Aug;20(8):584-91. PMID: 20609337
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Substances : Chocolate
Diseases : Gestational Diabetes, Pre-Eclampsia
[+]

Coenzyme Q10 supplementation during pregnancy reduces the risk of prre-eclampsia. Apr 01, 2009

Pubmed Data : Int J Gynaecol Obstet. 2009 Apr;105(1):43-5. Epub 2009 Jan 19. PMID: 19154996
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Pre-Eclampsia
[+]

Daily supplementation with ferrous sulphate results in greater lipid peroxidation which is associated with significantly higher risk of pre-eclampsia.Jun 01, 2009

Pubmed Data : J Obstet Gynaecol Res. 2009 Jun ;35(3):438-45. PMID: 19527380
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Diseases : Lipid Peroxidation, Pre-Eclampsia, Prenatal Nutrition: Prevention of Problems
Problem Substances : Ferrous Sulphate, Industrial Iron
[+]

Dietary carotenoid intake and risk of developing preeclampsia.May 20, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Pregnancy Childbirth. 2022 May 21 ;22(1):427. Epub 2022 May 21. PMID: 35597902
Article Published Date : May 20, 2022
Study Type : Human Study
Additional Links
Substances : beta-Carotene, Carotenoids, Cryptoxanthin, Lutein, Lycopene
Diseases : Pre-Eclampsia
Additional Keywords : Risk Reduction
[+]

Dietary fiber intake in early pregnancy reduces the risk of preeclampsia. Aug 01, 2008

Pubmed Data : Am J Hypertens. 2008 Aug;21(8):903-9. Epub 2008 Jul 17. PMID: 18636070
Article Published Date : Aug 01, 2008
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Pre-Eclampsia
[+]

Effect of Ajwa dates consumption to inhibit the progression of preeclampsia threats on mean arterial pressure.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:2917895. Epub 2019 Dec 10. PMID: 31886194
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Dates
Diseases : Pre-Eclampsia
Pharmacological Actions : Antihypertensive Agents
[+]

Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia.Jan 31, 2018

Pubmed Data : J Clin Pharm Ther. 2018 Feb ;43(1):21-25. Epub 2017 Jul 20. PMID: 28726273
Article Published Date : Jan 31, 2018
Study Type : Human Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Hypertension, Pre-Eclampsia
Pharmacological Actions : Antihypertensive Agents
[+]

Flu vaccination causes measurable increases in inflammation in pregnant women which may increase the risk of preeclempsia and adverse outcomes such as preterm birth. Sep 20, 2011

Pubmed Data : Vaccine. 2011 Sep 20. Epub 2011 Sep 20. PMID: 21945263
Article Published Date : Sep 20, 2011
Study Type : Human Study
Additional Links
Diseases : CRP, Elevated CRP, Pre-Eclampsia, Pregnancy: Vaccination, Pregnancy Complications, Preterm Birth: Prevention , Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza
Adverse Pharmacological Actions : Interleukin-6 up-regulation, Tumor necrosis factorα (TNFα) up-regulation
[+]

Folic acid supplementation reduces hypertensive disorders during pregnancy. Jan 01, 2009

Pubmed Data : Saudi Med J. 2009 Jan;30(1):88-97. PMID: 19139780
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Substances : Folic Acid
Diseases : Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia
[+]

Guided imagery reduces blood pressure in pregnant women with hypertension.Dec 01, 2010

Pubmed Data : Birth. 2010 Dec ;37(4):296-306. PMID: 21083721
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Diseases : Hypertension, Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia
Therapeutic Actions : Guided Imagery
Pharmacological Actions : Antihypertensive Agents
[+]

Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation.Jan 02, 2020

Pubmed Data : Gut. 2020 Jan 3. Epub 2020 Jan 3. PMID: 31900289
Article Published Date : Jan 02, 2020
Study Type : Human Study
Additional Links
Diseases : Dysbiosis, Pre-Eclampsia
Additional Keywords : Increased Risk
[+]

High dosage of folic acid supplement from 3 months before pregnancy until the entire pregnancy reduces the recurrent pre-eclampsia.Jan 13, 2020

Pubmed Data : Pregnancy Hypertens. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31987769
Article Published Date : Jan 13, 2020
Study Type : Human Study
Additional Links
Substances : Folic Acid
Diseases : Pre-Eclampsia
Additional Keywords : Risk Reduction
[+]

High intake of vegetables, fruits and vegetable oils is associated with reduced risk of preeclampsia. Jun 01, 2009

Pubmed Data : J Nutr. 2009 Jun;139(6):1162-8. Epub 2009 Apr 15. PMID: 19369368
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Pre-Eclampsia
[+]

Hyperhomocysteinaemia, vascular related pregnancy complications respond favorably to vitamin supplementation in pregnant women of Pakistan.Sep 01, 2010

Pubmed Data : J Pak Med Assoc. 2010 Sep;60(9):741-5. PMID: 21381582
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Substances : B-complex, Vitamin B-12, Vitamin B-6
Diseases : Albuminuria: Pregnancy-Associated, Eclampsia, High Homocysteine, Infants: Low Birth Weight, Placental abruption, Pre-Eclampsia, Pregnancy Complications
[+]

L-arginine supplementation is a safe, efficient strategy for treating preeclampsia. Jan 01, 2005

Pubmed Data : Eur J Clin Invest. 2005 Jan;35(1):32-7. PMID: 15638817
Article Published Date : Jan 01, 2005
Study Type : Human Study
Additional Links
Substances : Arginine
Diseases : Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia
Pharmacological Actions : Hypotensive
[+]

L-arginine supplementation is beneficial in prolonging pregnancy and reducing blood pressure in patients with gestational hypertension. Jan 01, 2007

Pubmed Data : Hypertens Pregnancy. 2007;26(1):121-30. PMID: 17454224
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Arginine
Diseases : Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia
[+]

Low vitamin C consumption is associated higher risk of pre-eclampsia. Jul 01, 2002

Pubmed Data : Epidemiology. 2002 Jul;13(4):409-16. PMID: 12094095
Article Published Date : Jul 01, 2002
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Pre-Eclampsia
[+]

Maternal periodontal disease is associated with an increased risk for preeclampsia.Feb 01, 2003

Pubmed Data : Obstet Gynecol. 2003 Feb;101(2):227-31. PMID: 12576243
Article Published Date : Feb 01, 2003
Study Type : Human Study
Additional Links
Diseases : Periodontal Diseases, Pre-Eclampsia, Pregnancy Complications
Additional Keywords : Diseases that are Linked
[+]

Maternal vitamin D deficiency increases the risk of preeclampsia.Sep 01, 2007

Pubmed Data : J Clin Endocrinol Metab. 2007 Sep ;92(9):3517-22. Epub 2007 May 29. PMID: 17535985
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Pre-Eclampsia, Vitamin D Deficiency
[+]

Omega-3 are beneficial in preventing pre-eclampsia.Sep 01, 2007

Pubmed Data : Ann Epidemiol. 2007 Sep ;17(9):663-8. Epub 2007 May 23. PMID: 17521921
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Pre-Eclampsia
[+]

Omega-3 Fatty Acid consumption may contribute to a reduction in risk of preeclampsia. May 01, 1995

Pubmed Data : Epidemiology. 1995 May;6(3):232-7. PMID: 7619928
Article Published Date : May 01, 1995
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia
[+]

Preeclampsia patients had gut microbiota dysbiosis and increased plasma lipopolysaccharide and trimethylamine-N-oxide levels.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Infect Microbiol. 2019 ;9:409. Epub 2019 Dec 3. PMID: 31850241
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Diseases : Dysbiosis, Lipopolysaccharide-Induced Toxicity, Pre-Eclampsia
Additional Keywords : Risk Factors
[+]

Prenatal exposure to ambient air pollution and adverse pregnancy outcomes.Jan 31, 2021

Pubmed Data : Int Arch Occup Environ Health. 2021 Feb ;94(2):309-324. Epub 2020 Sep 16. PMID: 32936369
Article Published Date : Jan 31, 2021
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Gestational Diabetes, Miscarriage, Pre-Eclampsia, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
[+]

Red light mitigates the deteriorating placental extracellular matrix in late onset of preeclampsia.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pregnancy. 2022 ;2022:3922368. Epub 2022 Apr 20. PMID: 35494491
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Diseases : Pre-Eclampsia
Therapeutic Actions : Light Therapy: Red Colored
Pharmacological Actions : Transforming growth factor beta (TGF-β) upregulation
[+]

Selenium supplementation may contribute to a reduction in the risk of pregnancy induced hypertension. Nov 01, 1994

Pubmed Data : Chin Med J (Engl). 1994 Nov;107(11):870-1. PMID: 7867399
Article Published Date : Nov 01, 1994
Study Type : Human Study
Additional Links
Substances : Selenium
Diseases : Hypertension: Pre-Eclampsia Induced, Pre-Eclampsia
[+]

Serum magnesium levels should be considered as a prognostic factor and supplementation intervention for pregnant women with preeclampsia.May 31, 2020

Pubmed Data : Enferm Clin. 2020 Jun ;30 Suppl 4:532-535. PMID: 32545134
Article Published Date : May 31, 2020
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Magnesium Deficiency, Pre-Eclampsia
Additional Keywords : Risk Factors
[+]

Silibinin downregulates the NF-κB pathway and NLRP1/NLRP3 inflammasomes in monocytes from pregnant women with preeclampsia.Apr 18, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Apr 19 ;24(8). Epub 2019 Apr 19. PMID: 31010153
Article Published Date : Apr 18, 2019
Study Type : Human Study
Additional Links
Substances : Silibinin
Diseases : Pre-Eclampsia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The effect of vitamin C on pulmonary oedema in patients with severe preeclampsia.Jan 12, 2021

Pubmed Data : Anaesth Crit Care Pain Med. 2021 Jan 13:100800. Epub 2021 Jan 13. PMID: 33453456
Article Published Date : Jan 12, 2021
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Pre-Eclampsia
[+]

The exposure to PM2.5, PM10, NO2, O3 were risk factors for preeclampsia in the first and second trimester of pregnancy.Nov 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Public Health. 2020 Nov 5 ;20(1):1663. Epub 2020 Nov 5. PMID: 33153479
Article Published Date : Nov 04, 2020
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Pre-Eclampsia
Additional Keywords : Risk Factors
[+]

These results demonstrated that maternal exposure to high level of BPA could be associated with an increased risk of pre-eclampsia.Nov 30, 2017

Pubmed Data : Eur J Public Health. 2017 Dec 1 ;27(6):1102-1107. PMID: 29186464
Article Published Date : Nov 30, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Pre-Eclampsia
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A
[+]

This study highlights the association between elevated maternal serum levels of BPA and preeclampsia.Feb 19, 2023

Pubmed Data : J Obstet Gynaecol Res. 2023 Feb 20. Epub 2023 Feb 20. PMID: 36806798
Article Published Date : Feb 19, 2023
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Pre-Eclampsia
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A
[+]

This study suggests that low maternal serum 25(OH)D concentrations increase pre-eclampsia risk and that vitamin D supplementation lowers this risk.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Nutr Metab. 2013 ;63(4):331-40. Epub 2014 Feb 28. PMID: 24603503
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Pre-Eclampsia, Vitamin D Deficiency
Additional Keywords : Risk Factors, Risk Reduction
[+]

Vitamin C and E supplementation reduces the risk of pre-eclampsia. Sep 01, 2002

Pubmed Data : Am J Obstet Gynecol. 2002 Sep;187(3):777-84. PMID: 12237663
Article Published Date : Sep 01, 2002
Study Type : Human Study
Additional Links
Substances : Vitamin C, Vitamin E
Diseases : Pre-Eclampsia
[+]

Vitamin C supplementation may prevent premature rupture of the chorioamniotic membranes. Apr 01, 2005

Pubmed Data : Am J Clin Nutr. 2005 Apr;81(4):859-63. PMID: 15817864
Article Published Date : Apr 01, 2005
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Pre-Eclampsia
[+]

Vitamin D has the potential of serving as a safe and effective adjuvant to oral nifedipine in treating women with preeclampsia against hypertension.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:865. Epub 2017 Nov 24. PMID: 29225576
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Pre-Eclampsia
Pharmacological Actions : Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitamin D supplementation may reduce the risk of preeclampsia in women who have never given birth to a child. Jun 01, 2003

Pubmed Data : J Nutr. 2003 Jun;133(6):1826-9. PMID: 19451820
Article Published Date : Jun 01, 2003
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Pre-Eclampsia
[+]

Vitamins C and E have protective effects against preeclampsia by alleviating the overall blood pressure.Jul 27, 2020

Pubmed Data : J Perinat Med. 2020 Jul 28 ;48(6):625-629. PMID: 32755100
Article Published Date : Jul 27, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin C, Vitamin E
Diseases : Pre-Eclampsia
Pharmacological Actions : Antihypertensive Agents
[+]

Women exposed to antidepressant and/or anxiolytic medication before the 16th week of pregnancy have a 3-fold increased risk for preeclampsia.Apr 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Pregnancy Childbirth. 2019 Apr 30 ;19(1):146. Epub 2019 Apr 30. PMID: 31039756
Article Published Date : Apr 29, 2019
Study Type : Human Study
Additional Links
Diseases : Pre-Eclampsia
Additional Keywords : Increased Risk
Problem Substances : Antidepressants
[+]

Puerarin attenuates preeclampsia-induced trophoblast mobility loss and inflammation by modulating miR-181b-5p/RBAK axis.Nov 06, 2021

Pubmed Data : Am J Reprod Immunol. 2021 Nov 7. Epub 2021 Nov 7. PMID: 34747081
Article Published Date : Nov 06, 2021
Study Type : Human In Vitro
Additional Links
Substances : Puerarin
Diseases : Pre-Eclampsia
Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator
[+]

Magnesium sulfate prophylaxis attenuates the postpartum effects of preeclampsia by promoting M2 macrophage polarization.Jul 26, 2020

Pubmed Data : Hypertens Res. 2020 Jul 27. Epub 2020 Jul 27. PMID: 32719464
Article Published Date : Jul 26, 2020
Study Type : Animal Study
Additional Links
Substances : Magnesium Sulfate
Diseases : Pre-Eclampsia
[+]

Apocynin inhibits placental TLR4/NF-κB signaling pathway and ameliorates preeclampsia-like symptoms.Sep 30, 2020

Pubmed Data : Pregnancy Hypertens. 2020 Oct ;22:210-215. Epub 2020 Oct 14. PMID: 33099123
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Apocynin
Diseases : Hypertension, Pre-Eclampsia
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Astaxanthin may be benefit for prevention and treatment of preeclampsia disease.Sep 30, 2014

Pubmed Data : Yao Xue Xue Bao. 2014 Oct ;49(10):1400-5. PMID: 25577869
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Pre-Eclampsia
Pharmacological Actions : Malondialdehyde Down-regulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Astragaloside IV alleviates lipopolysaccharide‐induced preeclampsia‐like phenotypes via suppressing the inflammatory responses.Oct 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Kaohsiung J Med Sci. 2020 Oct 22. Epub 2020 Oct 22. PMID: 33089927
Article Published Date : Oct 21, 2020
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Lipopolysaccharide-Induced Toxicity, Pre-Eclampsia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Astragaloside IV ameliorates preeclampsia-induced oxidative stress.Sep 13, 2020

Pubmed Data : Am J Physiol Endocrinol Metab. 2020 Sep 14. Epub 2020 Sep 14. PMID: 32924527
Article Published Date : Sep 13, 2020
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Oxidative Stress, Pre-Eclampsia
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Coenzyme Q10 attenuated placental inflammatory and oxidative stress, thereby protecting against preeclampsia.Jul 21, 2020

Pubmed Data : Microcirculation. 2020 Jul 22:e12651. Epub 2020 Jul 22. PMID: 32697403
Article Published Date : Jul 21, 2020
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Pre-Eclampsia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Additional Keywords : Risk Reduction
[+]

Coenzyme Q10 can alleviate preeclampsia symptoms and enhance the function of mitochondria in the placenta.Jul 30, 2019

Pubmed Data : Hypertens Pregnancy. 2019 Jul 31:1-6. Epub 2019 Jul 31. PMID: 31366258
Article Published Date : Jul 30, 2019
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Pre-Eclampsia
[+]

Extra virgin olive oil modulates vasodilator enzyme level by repairing angiogenesis function in rat model of preeclampsia.Feb 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Family Reprod Health. 2020 Mar ;14(1):38-44. PMID: 32863837
Article Published Date : Feb 29, 2020
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Pre-Eclampsia
Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors
[+]

Gastrodin improves preeclampsia-induced cell apoptosis by regulation of TLR4/NF-κB.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2020 Feb ;8(2):820-829. Epub 2020 Jan 10. PMID: 32148791
Article Published Date : Jan 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gastrodin
Diseases : Pre-Eclampsia
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Ginsenoside Rg2 ameliorates brain injury after intracerebral hemorrhage.Jul 15, 2021

Pubmed Data : Reprod Sci. 2021 Jul 16. Epub 2021 Jul 16. PMID: 34270001
Article Published Date : Jul 15, 2021
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Cerebral Hemorrhage, Pre-Eclampsia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Grape skin extract has a protective effect in experimental preeclampsia. Jan 01, 2007

Pubmed Data : Hypertens Pregnancy. 2007;26(1):89-100. PMID: 17454221
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Grape
Diseases : Pre-Eclampsia
[+]

Hesperidin improves physiological outcomes in an arginine vasopressin rat model of pre-eclampsia.Aug 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Fundam Clin Pharmacol. 2023 Aug 31. Epub 2023 Aug 31. PMID: 37652562
Article Published Date : Aug 30, 2023
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Pre-Eclampsia
Pharmacological Actions : Antihypertensive Agents
[+]

L-arginine supplementation decreased hypertension (HT), proteinuria, and ADMA levels indicating that taking L-arginine may be beneficial in preeclampsia treatment.Sep 01, 2008

Pubmed Data : Cell Biochem Funct. 2008 Sep-Oct;26(5):648-53. PMID: 18521818
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Hypertension, Hypertension: Pre-Eclampsia Induced, Oxidative Stress, Pre-Eclampsia
[+]

Mangiferin ameliorates placental oxidative stress and activates PI3K/Akt/mTOR pathway in mouse model of preeclampsia.Jan 26, 2020

Pubmed Data : Arch Pharm Res. 2020 Jan 27. Epub 2020 Jan 27. PMID: 31989480
Article Published Date : Jan 26, 2020
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Oxidative Stress, Pre-Eclampsia
Pharmacological Actions : Antioxidants
[+]

Oral magnesium supplementation improves the fetal outcome and prevents the development of symptoms of pre-eclampsia. Mar 01, 2002

Pubmed Data : Indian J Exp Biol. 2002 Mar;40(3):349-51. PMID: 12635709
Article Published Date : Mar 01, 2002
Study Type : Animal Study
Additional Links
Substances : Magnesium
Diseases : Pre-Eclampsia
[+]

Paeonol alleviates placental inflammation and apoptosis in preeclampsia.Aug 23, 2022

Pubmed Data : Kaohsiung J Med Sci. 2022 Aug 24. Epub 2022 Aug 24. PMID: 36054229
Article Published Date : Aug 23, 2022
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Pre-Eclampsia
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effect of fisetin on the lipopolysaccharide-induced preeclampsia.Dec 21, 2021

Pubmed Data : Hypertens Pregnancy. 2021 Dec 22:1-8. Epub 2021 Dec 22. PMID: 34933650
Article Published Date : Dec 21, 2021
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Lipopolysaccharide-Induced Toxicity, Pre-Eclampsia
Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The natural compound puerarin alleviates inflammation and apoptosis in experimental cell and rat preeclampsia models.Sep 30, 2021

Pubmed Data : Int Immunopharmacol. 2021 Oct ;99:108001. Epub 2021 Jul 24. PMID: 34311188
Article Published Date : Sep 30, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Pre-Eclampsia
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-4 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Treatment with apocynin selectively restores hippocampal arteriole function and seizure-induced hyperemia in a model of preeclampsia.Jul 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cereb Blood Flow Metab. 2022 Aug ;42(8):1425-1436. Epub 2022 Feb 9. PMID: 35137612
Article Published Date : Jul 31, 2022
Study Type : Animal Study
Additional Links
Substances : Apocynin
Diseases : Pre-Eclampsia, Seizures
Pharmacological Actions : Neuroprotective Agents
[+]

Vitexin ameliorates preeclampsia phenotypes by inhibiting TFPI-2 and HIF-1α/VEGF.Nov 30, 2019

Pubmed Data : Drug Dev Res. 2019 Dec ;80(8):1120-1127. Epub 2019 Sep 4. PMID: 31486114
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Pre-Eclampsia
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

SIRT1-dependent effects of resveratrol and grape juice in an in vitro model of preeclampsia.Aug 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Aug 28 ;131:110659. Epub 2020 Aug 28. PMID: 32866809
Article Published Date : Aug 27, 2020
Study Type : In Vitro Study
Additional Links
Substances : Grape, Resveratrol
Diseases : Pre-Eclampsia
Pharmacological Actions : Antioxidants, SIRT1 Activator
[+]

Antioxidant supplementation may reduce the risk for pre-eclampsia. Nov 01, 2005

Pubmed Data : Proc Nutr Soc. 2005 Nov;64(4):491-501 PMID: 16313693
Article Published Date : Nov 01, 2005
Study Type : Review
Additional Links
Substances : Antioxidant formulas
Diseases : Pre-Eclampsia
[+]

Astaxanthin inhibiting oxidative stress damage of placental trophoblast cells in vitro.Oct 24, 2020

Pubmed Data : Syst Biol Reprod Med. 2020 Oct 25:1-10. Epub 2020 Oct 25. PMID: 33103484
Article Published Date : Oct 24, 2020
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Hydrogen Peroxide Induced Toxicity, Pre-Eclampsia
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Immunomodulatory effects of vitamin D in pregnancy and beyond.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2019 ;10:2739. Epub 2019 Nov 22. PMID: 31824513
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Antiphospholipid Syndrome, Autoimmune Diseases, Infertility: Female, Pre-Eclampsia
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Immunomodulatory
[+]

Magnesium may prevent and treat preeclampsia. Feb 01, 1998

Pubmed Data : Neurology. 1998 Feb;50(2):466-70. PMID: 18949985
Article Published Date : Feb 01, 1998
Study Type : Review
Additional Links
Substances : Magnesium, Magnesium Sulfate
Diseases : Pre-Eclampsia
Pharmacological Actions : Hypotensive
[+]

Paeoniflorin alleviated preeclampsia-related endothelial dysfunction.Dec 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2020 Dec 11. Epub 2020 Dec 11. PMID: 33590855
Article Published Date : Dec 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Endothelial Dysfunction, Pre-Eclampsia
Pharmacological Actions : Apoptotic
[+]

Procyanidin B2 ameliorates endothelial dysfunction and impaired angiogenesis via the Nrf2/PPARγ/sFlt-1 axis in preeclampsia.Feb 09, 2022

Pubmed Data : Pharmacol Res. 2022 Feb 10 ;177:106127. Epub 2022 Feb 10. PMID: 35150862
Article Published Date : Feb 09, 2022
Study Type : In Vitro Study
Additional Links
Substances : Procyanidin B2
Diseases : Endothelial Dysfunction, Pre-Eclampsia
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Resveratrol induces SIRT1-Dependent autophagy to prevent H2O2-Induced oxidative stress and apoptosis in HTR8/SVneo cells.Jan 10, 2020

Pubmed Data : Placenta. 2020 Jan 11 ;91:11-18. Epub 2020 Jan 11. PMID: 31941613
Article Published Date : Jan 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Hydrogen Peroxide Induced Toxicity, Pre-Eclampsia
Pharmacological Actions : Antioxidants, Cytoprotective
[+]

Roles of exosomes-derived lncRNAs in preeclampsia.Jun 18, 2021

Pubmed Data : Eur J Obstet Gynecol Reprod Biol. 2021 Jun 19 ;263:132-138. Epub 2021 Jun 19. PMID: 34214799
Article Published Date : Jun 18, 2021
Study Type : Review
Additional Links
Diseases : Pre-Eclampsia
Additional Keywords : Exosomes
[+]

The role of magnesium in different inflammatory diseases.Jul 31, 2019

Pubmed Data : Inflammopharmacology. 2019 Aug ;27(4):649-661. Epub 2019 Jun 6. PMID: 31172335
Article Published Date : Jul 31, 2019
Study Type : Review
Additional Links
Substances : Magnesium
Diseases : Asthma, Atherosclerosis, Inflammation, Magnesium Deficiency, Pre-Eclampsia, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

These observations suggest that EGCG is a novel therapeutic candidate for preeclampsia.Oct 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2020 Oct 15 ;26:e926924. Epub 2020 Oct 15. PMID: 33056943
Article Published Date : Oct 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Endothelial Dysfunction, Pre-Eclampsia
Pharmacological Actions : Anti-Angiogenic
[+]

Vitamin D intake in infancy reduces the risk of pre-eclampsia much later in life. Sep 01, 2007

Pubmed Data : Eur J Clin Nutr. 2007 Sep;61(9):1136-9. Epub 2007 Jan 31. PMID: 17268418
Article Published Date : Sep 01, 2007
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Infant Nutrition, Pre-Eclampsia
Additional Keywords : Risk Reduction

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