Promyelocytic leukemia

Name	AC	CK
Curcumin	19	19
Turkey Tail Mushroom	3	12
Vitamin C	7	11
Vitamin C: Intravenous	2	10
Resveratrol	6	6
Flavonoids	4	4
Bay leaf	3	3
Chlorella (Algae)	1	3
Garlic	3	3
Ginsenosides	3	3
Panax Ginseng	2	3
Salvia miltiorrhiza	1	3
Vitamin D	3	3
Andrographis	2	2
Anthurium schlechtendalii	1	2
Artemisinin	2	2
Berberine	2	2
Hibiscus sabdariffa	2	2
Luteolin	2	2
Olive leaf extract	2	2
Orange	2	2
Organosulfur Compounds	2	2
Oridonin	2	2
Peanut	2	2
Piceatannol	2	2
Quercetin	2	2
Stilbenes	2	2
Sulforaphane	2	2
Tanshinone IIA	2	2
Vitamin K	2	2
Agrimony	1	1
Allicin	1	1
Andrographolide	1	1
Arachidin-1	1	1
Asiatic Acid	1	1
Asparagus	1	1
Barberry	1	1
Betulinic acid	1	1
Blueberry	1	1
Burdock	1	1
Butchers Broom	1	1
Capsaicin	1	1
Catechin	1	1
Chinese Skullcap	1	1
Citrus Triterpenoids	1	1
Cordyceps sinensis	1	1
Coriolus versicolor	1	1
Cranberry	1	1
D-Limonene	1	1
Daisy	1	1
EGCG (Epigallocatechin gallate)	1	1
Ellagic Acid	1	1
Fisetin	1	1
Fucoidan	1	1
Garcinia indica	1	1
Ginseng (Siberian)	1	1
Grapefruit seed oil	1	1
Green Tea	1	1
Guarana	1	1
Hawthorn	1	1
Hesperidin	1	1
Humic Acid	1	1
Isoflavones	1	1
Isothiocyanates	1	1
Juniper	1	1
Kaempferia parviflora	1	1
Kaempferol	1	1
Lactoferrin	1	1
Licorice	1	1
Lignans	1	1
Loquat	1	1
Magnolol	1	1
Mangiferin	1	1
Mangosteen	1	1
Mastic gum	1	1
Medicinal Mushrooms	1	1
Milk Thistle	1	1
Mugwort	1	1
Myricetin	1	1
NAC (N-acetyl-L-cysteine)	1	1
Noni	1	1
Papaya	1	1
Peony	1	1
Polyphenols	1	1
Puerarin	1	1
Raspberry	1	1
Rhodiola (Tibetan Ginseng)	1	1
Roselle	1	1
Rosemaric Acid	1	1
Rutin	1	1
Sandalwood	1	1
Shikonin	1	1
Silibinin	1	1
Spinach	1	1
Turmerones	1	1
Urolithin A	1	1
Vitamin E	1	1
Walnut	1	1
Water: Electrolyzed Reduced	1	1
White Button Mushroom	1	1
Wogonin	1	1
beta-Carotene	1	1

Name	AC	CK	Focus
Photobiomodulation	1	1

Pharmacological Actions : Antioxidants, Apoptotic, Chemotherapeutic, Radioprotective

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15,16-dihydrotanshinone I from the functional food Salvia miltiorrhiza exhibits anticancer activity in human HL-60 leukemia cells.Aug 16, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2015 Aug 17 ;16(8):19387-400. Epub 2015 Aug 17. PMID: 26287183

Article Published Date : Aug 16, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Salvia miltiorrhiza

Diseases : Leukemia, Promyelocytic leukemia

Pharmacological Actions : Apoptotic

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Chlorella sorokiniana extract prevents cisplatin-induced myelotoxicity.Dec 31, 2019

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Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:7353618. Epub 2020 Jan 25. PMID: 32047579

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Pubmed Data : J Cell Biochem. 2019 04 ;120(4):5620-5627. Epub 2018 Oct 15. PMID: 30320906

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Pubmed Data : Exp Hematol. 2016 Jun ;44(6):466-73. Epub 2016 Mar 15. PMID: 26992299

Article Published Date : May 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Ginseng (Siberian)

Diseases : Cancers: Drug Resistant, Leukemia, Promyelocytic leukemia

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Histone deacetylase inhibitor

Additional Keywords : Epigenetic Modification In Cancer, Plant Extracts

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Pubmed Data : Mol Med Rep. 2015 Jul ;12(1):1429-34. Epub 2015 Mar 24. PMID: 25815462

Article Published Date : Jun 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Asiatic Acid

Diseases : Leukemia, Promyelocytic leukemia

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation

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Asparagus contains steroidal phytochemicals capable of irreversibly inhibiting DNA synthesis in human leukemia HL-60 cell in culture.Jun 01, 1997

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Pubmed Data : Planta Med. 1997 Jun;63(3):258-62. PMID: 9225609

Article Published Date : Jun 01, 1997

Study Type : In Vitro Study

Additional Links

Substances : Asparagus

Diseases : Leukemia, Promyelocytic leukemia

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Association of leukemia target genes Tet2, Bcl2, and Slc23a2 in vitamin C pathways.Aug 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Wien Med Wochenschr. 1997;147(14):323-7. PMID: 19909759

Article Published Date : Jan 01, 1997

Study Type : In Vitro Study

Additional Links

Substances : Barberry, Berberine

Diseases : Promyelocytic leukemia

Pharmacological Actions : Antiproliferative , Apoptotic

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Berberine maintains the neutrophil N1 phenotype to reverse cancer cell resistance to doxorubicin.Dec 31, 2018

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Pubmed Data : Front Pharmacol. 2019 ;10:1658. Epub 2020 Jan 29. PMID: 32063859

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Pubmed Data : Anticancer Drugs. 2004 Jul;15(6):619-24. PMID: 15205607

Pubmed Data : Eur J Pharmacol. 2001 May 25;420(2-3):83-90. PMID: 11408028

Article Published Date : May 25, 2001

Study Type : In Vitro Study

Additional Links

Substances : Capsaicin, Vitamin D

Diseases : Promyelocytic leukemia

Pharmacological Actions : Chemosensitizer, Enzyme Inhibitors

Additional Keywords : Drug-Plant-Vitamin Synergies, Natural Substance Synergy

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Changes in chemical components and antitumor activity during the heating process of Fructus Arctii.Nov 30, 2019

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Pubmed Data : Biol Pharm Bull. 2006 Apr;29(4):670-4. PMID: 16595897

Article Published Date : Apr 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Cordyceps sinensis

Diseases : Leukemia, Promyelocytic leukemia

Pharmacological Actions : Antiproliferative , Apoptotic

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Corosolic acid may be a potential chemotherapeutic agent for the treatment of human leukemia.Dec 31, 2012

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Hesperidin could be proposed as a candidate molecule in chemoprevention in epigenetic therapy purposes.Jan 26, 2017

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Pubmed Data : Mol Carcinog. 2017 Jan 27. Epub 2017 Jan 27. PMID: 28130850

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Pubmed Data : J Agric Food Chem. 2010 Jul 14 ;58(13):7641-8. PMID: 20536138

Article Published Date : Jul 13, 2010

Study Type : In Vitro Study

Additional Links

Substances : Andrographis, Andrographolide

Diseases : Promyelocytic leukemia

Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

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Additional Keywords : Xanthones

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Mangosteen strongly inhibits a human promyelocytic leukemia cell line.Aug 01, 2003

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Pubmed Data : J Nat Prod. 2003 Aug;66(8):1124-7. PMID: 12932141

Article Published Date : Aug 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Mangosteen

Diseases : Leukemia, Promyelocytic leukemia

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Mastic gum has antibacterial activity and inhibits cell death of oral polymorphonuclear leukocytes (e.g. neutrophils). Mastic gum is highly cytotoxic to promyelocytic leukemia cells. Mar 01, 2009

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Pubmed Data : In Vivo. 2009 Mar-Apr;23(2):215-23. PMID: 19414406

Article Published Date : Mar 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Mastic gum

Diseases : Neutropenia, Neutropenia: Chemotherapy Induced, Neutropenia: Cyclic, Neutropenia: Severe Congenital, Promyelocytic leukemia

Pharmacological Actions : Anti-Bacterial Agents

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Natsuhaze extract had high antioxidant activity and growth inhibitory effect on HL-60 human leukemia cells.Feb 14, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Plants (Basel). 2013 Feb 15 ;2(1):57-71. Epub 2013 Feb 15. PMID: 27137366

Article Published Date : Feb 14, 2013

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Pubmed Data : Neoplasma. 2005;52(4):273-9. PMID: 16059641

Article Published Date : Jan 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Quercetin

Diseases : Cancers: Drug Resistant, Promyelocytic leukemia

Pharmacological Actions : Apoptotic

Additional Keywords : Drug: Doxorubicin

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Quercetin reverses multi-drug resistance of adriamycin resistant promyelocytic leukemia cells. Jun 01, 2005

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Pubmed Data : Zhonghua Zhong Liu Za Zhi. 2005 Jun;27(6):326-9. PMID: 16117892

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Pubmed Data : Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2024 Apr ;32(2):416-421. PMID: 38660845

Article Published Date : Mar 31, 2024

Study Type : In Vitro Study

Additional Links

Substances : Shikonin

Diseases : Promyelocytic leukemia

Pharmacological Actions : Apoptotic, Autophagy Up-regulation

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Silibinin induces cell differentiation of human promyelocytic leukemia cells into monocytes. Jun 15, 2001

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Pubmed Data : Biochem Pharmacol. 2001 Jun 15;61(12):1487-95. PMID: 11377378

Article Published Date : Jun 15, 2001

Study Type : In Vitro Study

Additional Links

Substances : Milk Thistle, Silibinin

Diseases : Promyelocytic leukemia

Pharmacological Actions : Antioxidants, Enzyme Inhibitors

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biosci Biotechnol Biochem. 2007 May ;71(5):1306-12. Epub 2007 May 7. PMID: 17485840

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Pubmed Data : Biochemistry. 2002 Oct 29;41(43):12995-3002. PMID: 12390026

Article Published Date : Oct 29, 2002

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Acute Myeloid Leukemia, Breast Cancer, Cervical Cancer, Promyelocytic leukemia

Pharmacological Actions : Antioxidants, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Vitamin E and rutin work synergistically to inhibit VEGF-1 in human promyelocytic leukemia cells. Feb 12, 2010

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Pubmed Data : Chem Biol Interact. 2010 Feb 12;183(3):434-41. Epub 2009 Dec 16. PMID: 20015448

View the Evidence: 135 Abstracts with Promyelocytic leukemia Research

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Turkey tail mushroom contains a polysaccharopeptide which demonstrates chemotherapeutic activity against both leukemic and breast cancer cells.Mar 01, 2008

These results indicate that all analyzed cell lines including are highly sensitive to the cytotoxic, pro-oxidant effects of high doses of sodium ascorbate.Oct 31, 2015

Treatment with high extracellular concentrations of ascorbic acid alone directly induced cancer cell death.Dec 31, 2016

15,16-dihydrotanshinone I from the functional food Salvia miltiorrhiza exhibits anticancer activity in human HL-60 leukemia cells.Aug 16, 2015

Chlorella sorokiniana extract prevents cisplatin-induced myelotoxicity.Dec 31, 2019

Panax ginseng increases the susceptibility of myelocytic leukemic cells to cytotoxic drugs. Jan 01, 1999

The Maya healing plant Anthurium schlechtendalii exhibits strong in vitro anticancer activity against promyelocytic leukemia. Oct 01, 2009

A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells.Jan 31, 2016

Antiproliferative activity of Citrus juices and HPLC evaluation of their flavonoid composition.Aug 31, 2007

Cytotoxic and apoptotic effects of different extracts of Artemisia turanica Krasch. on K562 and HL-60 cell lines Dec 31, 2012

Synergistic antitumor activity of oridonin and valproic acid on HL-60 leukemia cells.Dec 31, 2018

1,8-cineole, a main componenet of the essential oil of Bay leaf, induces programmed cell death in human leukemia cell lines.Jul 01, 2002

20-(s)-ginsenoside Rg3 effectively induces apoptosis in human leukemic cells.Sep 30, 2014

A comparative study of anti-leukemic effects of kaempferol and epigallocatechin-3-gallate (EGCG) on human leukemia HL-60 cells.Jun 30, 2021

A lactoferrin-derived peptide with cationic residues concentrated in a region of its helical structure induces necrotic cell death in a leukemic cell line (HL-60).Aug 31, 2008

A potential target of tanshinone IIA for acute promyelocytic leukemia revealed by inverse docking and drug repurposing.Dec 31, 2013

A. senticosus exhibited a potential for inhibition of histone deacetylase.May 31, 2016

Agrimony induces programmed cell death in human promyelocytic leukemia cells. Jul 01, 1978

Allicin inhibits cell growth and induces programmed cell death in leukemia and lymphoma cells. Aug 01, 2008

Andrographolide, a compounds in Andrographis, inhibits growth of acute promyelocytic leukaemia cells.Jan 01, 2009

Anthocyanins from roselle extract arrest cell cycle G2/M phase transition via ATM/Chk pathway in p53-deficient leukemia HL-60 cells.Mar 31, 2017

Anthraquinones with potential antiproliferative activities from the fruits of Morinda citrifolia.Dec 12, 2021

Anti-cancer effect of spinach glycoglycerolipids as angiogenesis inhibitors.Dec 31, 2010

Antiviral, cytotoxic, and antioxidant activities of three edible agaricomycetes mushrooms: Pleurotus columbinus, Pleurotus sajor-caju, and Agaricus bisporus.Aug 07, 2021

Apoptosis induced by the flavonoid from lemon fruit and its metabolites in HL-60 cells.Apr 30, 2000

Apoptosis-inducing activity and antiproliferative effect of Paeoniflorigenone from moutan cortex.May 31, 2017

Ar-turmerone, a compound within turmeric, induces programmed cell death in two human cancer lines.Sep 01, 1998

Arachidin-1, a peanut stilbenoid, induces programmed cell death in human leukemia cells.Nov 10, 2010

Artemisinin enhances human promyelocytic leukemia cell differentiation.Dec 15, 2003

Ascorbic acid synergistically potentiates phloxine b-induced photocytotoxicity in human acute promyelocytic leukemia cells.Mar 31, 2014

Asiatic acid may be a valuable agent for molecular targeted therapy of human acute leukemia.Jun 30, 2015

Asparagus contains steroidal phytochemicals capable of irreversibly inhibiting DNA synthesis in human leukemia HL-60 cell in culture.Jun 01, 1997

Association of leukemia target genes Tet2, Bcl2, and Slc23a2 in vitamin C pathways.Aug 31, 2019

Bay leaf contains compounds which induce programmed cell death in leukemia cells.Aug 01, 2003

Bay leaf contains compounds which induce programmed cell death in leukemia cells. Jan 01, 2004

Berberine and a Barberry (Berberis lycium) extract inhibit human promyelocytic leukemia proliferation. Jan 01, 1997

Berberine maintains the neutrophil N1 phenotype to reverse cancer cell resistance to doxorubicin.Dec 31, 2018

Beta-carotene induces apoptosis in leukemia cells.Feb 10, 2002

Beta-Phenethyl isothiocyanate is a promising compound for potential use in leukemia treatment.Dec 14, 2011

Betulinic acid enhances vitamin D3-induced differentiation in human promyelocytic leukemia cells. Jul 01, 2004

Black raspberries contain a compound which has an anticancer effect on leukemia and lymphoma cell lines.May 04, 2007

Butcher's broom contains a phytochemical (saponin) which inhibits human leukemia cells.Feb 01, 1998

Capsaicin potentiates the vitamin D3-induced and all-trans retinoic acid-induced differentiation of human promyelocytic leukemia cells. May 25, 2001

Changes in chemical components and antitumor activity during the heating process of Fructus Arctii.Nov 30, 2019

Compound K, a metabolite of ginseng saponin, induces apoptosis in human promyelocytic leukemia cells. Jan 01, 2008

Compounds from orange peel inhibit the proliferation of promyelocytic leukemia (HL-60) cells.May 15, 2007

Cordyceps has potent cytotoxic effects against the proliferation of human premyelocytic leukemia cells. - Article 1Apr 01, 2006

Corosolic acid may be a potential chemotherapeutic agent for the treatment of human leukemia.Dec 31, 2012

Cranberry extract initiates intrinsic apoptosis in HL-60 cells by increasing BAD activity through inhibition of AKT phosphorylation.Mar 05, 2020

Crude extracts and phytochemicals derived from H. sabdariffa has antimicrobial, antiparasitic, and anticancer properties.Dec 31, 2015

Curcumin abolished the resistance of human promyelocytic leukemia cells to programmed cell death. Aug 21, 2006

Curcumin and gallic acid are cytotoxic to leukemia and oral cancer cells.Sep 01, 1998

Curcumin can inhibit the growth and programmed cell death in acute promyelocytic leukemia (APL) cells.Apr 01, 2010

Curcumin enhances leukemia cell differentiation. Jan 01, 1997

Curcumin enhances programmed cell death in leukemia cells.Jan 01, 2003

Curcumin exhibits anti-cancer activity against promyelocytic leukemia and submandibular cancer cells.Nov 01, 2005

Curcumin exhibits anti-leukemia properties.Feb 23, 2007

Curcumin has a prooxidant action on promyelocytic leukemia cells.Jun 01, 2009

Curcumin induces programmed cell death and disturbs cell cycle progression in leukemia cells.Jan 01, 2002

Curcumin induces programmed cell death in leukemia cells. May 01, 2008

Curcumin inhibits human leukemia cells.Nov 15, 1996

Curcumin inhibits leukemia cell proliferation. Nov 01, 2003

Curcumin may enhance the chemotherapeuic efficacy of all-trans retinoic acid against human promyelocytic leukemia cells. Jan 01, 1997

Curcumin may overcome resistance in leukemia cells. Oct 15, 2006

Curcumin modulates cell cycle in leukemia cells and enhances programmed cell death. Jan 01, 2000

Curcumin suppresses human promyelocytic leukemia cells.May 31, 2002

Curcumin's induction of programmed cell death in human leukemia cells is associated with inhibition of telomerase activity.Mar 01, 2007

Diallyl disulfide could be a promising anti leukemia therapeutic compound.Feb 29, 2020

Diallyl disulfide downregulating RhoGDI2 induces differentiation and inhibit invasion via the Rac1/Pak1/LIMK1 pathway in human leukemia HL-60 cells.Apr 30, 2023

Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives induced programmed cell death in human promyelocytic leukemia cells. Jul 01, 2008

Effects of D-limonene on leukemia cells HL-60 and K562 in vitroJul 31, 2006

Effects of pre-radiation exposure to LLLT of normal and malignant cells.May 31, 2016

Promyelocytic leukemia

View the Evidence:
135 Abstracts with Promyelocytic leukemia Research