Prostate Cancer: Prevention

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49 Substances Researched for Prostate Cancer: Prevention
NameACCKFocus
Broccoli425Locked
Cruciferous Vegetables322Locked
Bok Choy120Locked
Cabbage120Locked
Coffee120Locked
Collards120Locked
Genistein220Locked
Kale120Locked
Mustard Greens120Locked
Vitamin C120Locked
Vitamin E220Locked
Sulforaphane414Locked
Tomato314Locked
Green Tea313Locked
Lycopene212Locked
Polyphenols211Locked
Black Tea110Locked
Carotenoids110Locked
Cryptoxanthin110Locked
Daidzein110Locked
Enterolactone110Locked
Fiber110Locked
Flaxseed110Locked
Isoflavones110Locked
Lignans110Locked
Lutein110Locked
Soy110Locked
Vitamin K110Locked
Vitamin K2110Locked
Vitamin K2: Menaquinones (MK-4-14) 110Locked
Watermelon110Locked
Zeaxanthin110Locked
beta-Carotene110Locked
phytoestrogens110Locked
Quercetin23Locked
Ellagic Acid12Locked
Fermented Foods and Beverages12Locked
Indole-3-Carbinol22Locked
Pomegranate12Locked
Resveratrol12Locked
Rice Bran12Locked
Rice: Brown12Locked
Sprouts12Locked
Argan Oil11Locked
Catechin 11Locked
EGCG (Epigallocatechin gallate)11Locked
Plant Sterols/Stanols11Locked
Selenium11Locked
Silibinin11Locked
2 Problem Substances Researched for Prostate Cancer: Prevention
NameACCKFocus
Alcohol Consumption110Locked
Meat: Cooked12Locked
1 Therapeutic Actions Researched for Prostate Cancer: Prevention
NameACCKFocus
Sunlight exposure220Locked
1 Problematic Actions Researched for Prostate Cancer: Prevention
NameACCKFocus
Western Diet212Locked
Related Topics

Prostate Cancer: Prevention is a Sub of the following Topics

View the Evidence:
33 Abstracts with Prostate Cancer: Prevention Research

[+]

Cruciferous vegetables intake is related to the decreased risk of prostate cancer.Jan 31, 2012

Pubmed Data : Int J Urol. 2012 Feb ;19(2):134-41. Epub 2011 Nov 28. PMID: 22121852
Article Published Date : Jan 31, 2012
Study Type : Meta Analysis
Additional Links
Substances : Cruciferous Vegetables
Diseases : Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive
[+]

Evidence exists indicating that Brassica vegetables reduce prostate cancer risk.Jan 01, 2002

Pubmed Data : Nutr Cancer. 2002;42(1):1-9. PMID: 12235639
Article Published Date : Jan 01, 2002
Study Type : Meta Analysis
Additional Links
Substances : Bok Choy, Broccoli, Cabbage, Collards, Kale, Mustard Greens
Diseases : Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Risk Reduction
[+]

The present meta-analysis showed that intake of vitamin C from food was inversely associated with prostate cancer risk. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer. 2015 ;6(9):913-21. Epub 2015 Jul 28. PMID: 26284143
Article Published Date : Dec 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Vitamin C
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive
Additional Keywords : Dose Response, Risk Reduction
[+]

These findings suggest that coffee consumption may be associated with a reduced risk of prostate cancer.Dec 31, 2014

Pubmed Data : Nutr Cancer. 2015 ;67(3):392-400. Epub 2015 Feb 23. PMID: 25706900
Article Published Date : Dec 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Coffee
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Additional Keywords : Risk Reduction
[+]

A western-style diet may lead to increased risks for prostate cancer, especially aggressive prostate cancer.May 01, 2008

Pubmed Data : Ann Epidemiol. 2008 May;18(5):364-70. Epub 2008 Feb 8. PMID: 18261927
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Anti Therapeutic Actions : Western Diet
[+]

Dietary fiber intake might modulate the association between alcohol intake and risk of hormone dependent cancer.May 19, 2015

Pubmed Data : Am J Clin Nutr. 2015 May 20. Epub 2015 May 20. PMID: 25994566
Article Published Date : May 19, 2015
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Breast Cancer, Prostate Cancer, Prostate Cancer: Prevention
Additional Keywords : Risk Reduction
Problem Substances : Alcohol Consumption
[+]

Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.Mar 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2013 Apr ;16(4):357-60. PMID: 23566060
Article Published Date : Mar 31, 2013
Study Type : Human Study
Additional Links
Substances : Enterolactone, Flaxseed, Lignans
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Antiproliferative , Chemopreventive, Vascular Endothelial Growth Factor A Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Genistein and daidzein consumption are associated with a lower risk of prostate cancer. Aug 01, 2009

Pubmed Data : J Altern Complement Med. 2009 Aug;15(8):905-9. PMID: 19838933
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : Daidzein, Genistein, Isoflavones
Diseases : Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Risk Reduction
[+]

Green tea induced changes in NFκB and systemic oxidation, and uptake of GT polyphenols in prostate tissue they may have a role in prostate cancer prevention and treatment.Mar 31, 2015

Pubmed Data : Prostate. 2015 Apr 1 ;75(5):550-9. Epub 2014 Dec 24. PMID: 25545744
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Substances : Black Tea, Green Tea, Polyphenols
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive, NF-kappaB Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Higher concentrations of circulating genistein may reduce the risk of prostate cancer.Jun 02, 2009

Pubmed Data : Br J Cancer. 2009 Jun 2;100(11):1817-23. Epub 2009 May 12. PMID: 19436304
Article Published Date : Jun 02, 2009
Study Type : Human Study
Additional Links
Substances : Genistein, phytoestrogens
Diseases : Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive
[+]

Increased exposure to sunlight may reduce prostate cancer risk. Sep 15, 2009

Pubmed Data : Int J Cancer. 2009 Sep 15;125(6):1414-23. PMID: 19444909
Article Published Date : Sep 15, 2009
Study Type : Human Study
Additional Links
Diseases : Prostate Cancer: Prevention
Therapeutic Actions : Sunlight exposure
[+]

Long-term supplementation with alpha-tocopherol (vitamin E) substantially reduced prostate cancer incidence and mortality in male smokers. Mar 18, 1998

Pubmed Data : J Natl Cancer Inst. 1998 Mar 18;90(6):440-6. PMID: 9521168
Article Published Date : Mar 18, 1998
Study Type : Human Study
Additional Links
Substances : Vitamin E
Diseases : Prostate Cancer: Prevention, Smoking
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Risk Reduction
[+]

Sulforaphane has a novel chemopreventive mechanism in human colon cancer cells and prostate epithelial cells, namely the inhibition of histone deacetylase (HDAC). IFeb 01, 2007

Pubmed Data : Exp Biol Med (Maywood). 2007 Feb;232(2):227-34. PMID: 17259330
Article Published Date : Feb 01, 2007
Study Type : Human Study
Additional Links
Substances : Sulforaphane
Diseases : Colon Cancer, Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive, Enzyme Inhibitors, Histone deacetylase inhibitor
[+]

Sunlight exposure reduces the risk of prostate cancer. Mar 31, 2003

Pubmed Data : Cancer Lett. 2003 Mar 31;192(2):145-9. PMID: 12668278
Article Published Date : Mar 31, 2003
Study Type : Human Study
Additional Links
Diseases : Prostate Cancer: Prevention
Therapeutic Actions : Sunlight exposure
Additional Keywords : Risk Reduction
[+]

The consumption of soy food is associated with a lower risk of prostate cancer in men. Nov 20, 2005

Pubmed Data : Int J Cancer. 2005 Nov 20;117(4):667-9. PMID: 15945102
Article Published Date : Nov 20, 2005
Study Type : Human Study
Additional Links
Substances : Soy
Diseases : Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

There is an inverse association between the intake of menaquinones and prostate cancer.Apr 01, 2008

Pubmed Data : Am J Clin Nutr. 2008 Apr;87(4):985-92. PMID: 18400723
Article Published Date : Apr 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin K, Vitamin K2, Vitamin K2: Menaquinones (MK-4-14)
Diseases : Prostate Cancer: Prevention
[+]

Vegetables and fruits rich in lycopene and other carotenoids may be protective against prostate cancer.Mar 01, 2005

Pubmed Data : Int J Cancer. 2005 Mar 1;113(6):1010-4. PMID: 15514967
Article Published Date : Mar 01, 2005
Study Type : Human Study
Additional Links
Substances : beta-Carotene, Carotenoids, Cryptoxanthin, Lutein, Lycopene, Tomato, Watermelon, Zeaxanthin
Diseases : Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

Vitamin E supplementation is associated with a statistically significant reduction in the incidence of prostate cancer. Nov 01, 2007

Pubmed Data : Ann Saudi Med. 2007 Nov-Dec;27(6):409-14. PMID: 18059122
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Substances : Vitamin E
Diseases : Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

"Dietary Resveratrol Prevents Development of High-Grade Prostatic Intraepithelial Neoplastic Lesions."Dec 16, 2012

Pubmed Data : Cancer Prev Res (Phila). 2012 Dec 17. Epub 2012 Dec 17. PMID: 23248098
Article Published Date : Dec 16, 2012
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : High-Grade Prostatic Intraepithelial Neoplastic Lesions, Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive
[+]

A Western-style diet induces hyperproliferation in the epithelial cells of the mouse prostate.May 01, 1997

Pubmed Data : Carcinogenesis. 1997 May;18(5):995-9. PMID: 9163686
Article Published Date : May 01, 1997
Study Type : Animal Study
Additional Links
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Anti Therapeutic Actions : Western Diet
[+]

Broccoli sprouts can serve as a good dietary source of sulforaphane in vivo and that they have significant inhibitory effects on prostate tumorigenesis.Oct 01, 2009

Pubmed Data : Pharm Res. 2009 Oct;26(10):2324-31. Epub 2009 Aug 8. PMID: 19669099
Article Published Date : Oct 01, 2009
Study Type : Transgenic Animal Study
Additional Links
Substances : Broccoli, Sprouts, Sulforaphane
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts
[+]

Combining green tea polyphenols and quercetin significantly enhanced the antiproliferative and proapoptotic effect in vivo. Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Biochem. 2014 Jan ;25(1):73-80. Epub 2013 Oct 10. PMID: 24314868
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Green Tea, Quercetin
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Bioavailability, Multidrug Resistance, Natural Substance Synergy
[+]

Dietary tomato components reduced testosterone regulated genes associated with early prostate carcinogenesis.Nov 30, 2014

Pubmed Data : Cancer Prev Res (Phila). 2014 Dec ;7(12):1228-39. Epub 2014 Oct 14. PMID: 25315431
Article Published Date : Nov 30, 2014
Study Type : Animal Study
Additional Links
Substances : Lycopene, Tomato
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Cancer Stem Cells, Gene Expression Regulation
[+]

Fermented brown rice and rice bran with Aspergillus oryzae has potential for the prevention of human prostate cancer.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 ;8(7). Epub 2016 Jul 11. PMID: 27409632
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Rice: Brown, Rice Bran
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

Pomegranate fruit juice suppressed androgen dependent prostate carcinogenesis.Oct 03, 2014

Pubmed Data : Prostate. 2014 Oct 4. Epub 2014 Oct 4. PMID: 25284475
Article Published Date : Oct 03, 2014
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid, Pomegranate
Diseases : Cancer: Prostate, Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Caspase-3 Activation, Chemopreventive
[+]

This study supports the hypothesis that a diet rich in tomato and broccoli can reduce or prevent dietary carcinogen induced cancers.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(11):e79842. Epub 2013 Nov 27. PMID: 24312188
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Broccoli, Tomato
Diseases : Breast Cancer, Cancers: All, Colorectal Cancer: Prevention , Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Dietary Concentrations, Dietary Modification
Problem Substances : Meat: Cooked
[+]

3,3'-diindolylmethane (DIM) has multiple anticancer properties making it one of the most hopeful phytochemicals in treating and preventing prostate cancer and HGPIN.Aug 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biomed Res. 2014 Sep ;28(5):339-48. Epub 2014 Apr 20. PMID: 25332705
Article Published Date : Aug 31, 2014
Study Type : Review
Additional Links
Substances : Cruciferous Vegetables, Indole-3-Carbinol
Diseases : High-Grade Prostatic Intraepithelial Neoplastic Lesions, Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Estrogenic, Anti-Inflammatory Agents, Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Risk Reduction
[+]

Polyphenols and sterols from virgin argan oil have antiproliferative and pro-apoptotic effects on prostate cancer cell lines.Dec 31, 2006

Pubmed Data : Cancer Detect Prev. 2007 ;31(1):64-9. Epub 2006 Dec 13. PMID: 17174037
Article Published Date : Dec 31, 2006
Study Type : In Vitro Study
Additional Links
Substances : Argan Oil, Plant Sterols/Stanols, Polyphenols
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Dose Response, Plant Extracts, Plant Oils
[+]

Quercetin combined with EGCG in vitro demonstrated enhanced inhibition of cell proliferation by increasing the intracellular concentration of EGCG and decreasing EGCG methylation.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Cancer. 2012 ;64(4):580-7. Epub 2012 Mar 27. PMID: 22452782
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Catechin , EGCG (Epigallocatechin gallate), Green Tea, Quercetin
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Chemopreventive
Additional Keywords : Bioavailability, Natural Substance Synergy
[+]

Selenium-enriched broccoli sprouts could potentially be used as an alternative selenium source for prostate cancer prevention and therapy.Jan 01, 2009

Pubmed Data : BMC Cancer. 2009;9:414. Epub 2009 Nov 30. PMID: 19943972
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Broccoli, Selenium
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Antiproliferative , Apoptotic
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

These mechanistic studies suggest that silibinin would be effective against PCA by targeting critical aberrant lipogenesis.Oct 29, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2014 Oct 30 ;5(20):10017-33. PMID: 25294820
Article Published Date : Oct 29, 2014
Study Type : In Vitro Study
Additional Links
Substances : Silibinin
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Cell cycle arrest, Chemopreventive
Additional Keywords : Gene Expression Regulation
[+]

This review summarizes evidence of the impact of SFN on epigenetic events related to the chemopreventive effects in preclinical and clinical studies of breast and prostate cancers.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Pharmacol Rep. 2015 Apr 1 ;1(2):102-111. PMID: 26042194
Article Published Date : Mar 31, 2015
Study Type : Review
Additional Links
Substances : Sulforaphane
Diseases : Breast Cancer, Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Epigenetic Modification In Cancer
[+]

This review summarizes the well established non epigenetic targets and highlights more recent evidence supporting these phytochemicals as epigenetic modulators for prostate cancer chemoprevention.Sep 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AAPS J. 2013 Oct ;15(4):951-61. Epub 2013 Jun 26. PMID: 23800833
Article Published Date : Sep 30, 2013
Study Type : Review
Additional Links
Substances : Cruciferous Vegetables, Indole-3-Carbinol, Sulforaphane
Diseases : Prostate Cancer, Prostate Cancer: Prevention
Pharmacological Actions : Chemopreventive
Additional Keywords : Epigenetic Modification In Cancer

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