Prostatic Diseases

Name	AC	CK	Focus
Tea Tree	1	2

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Coffee consumption and risk of prostate cancer: a systematic review and meta-analysis.Jan 10, 2021

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Pubmed Data : Arch Ital Urol Androl. 2019 Oct 2 ;91(3). Epub 2019 Oct 2. PMID: 31577096

Article Published Date : Oct 01, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : Green Tea

Diseases : Prostate Cancer

Pharmacological Actions : Chemopreventive

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Integrated evidence from this meta-analysis suggests that shift work is significantly associated with an increased risk of prostate cancer.Nov 07, 2017

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Pubmed Data : Carcinogenesis. 2017 Nov 8. Epub 2017 Nov 8. PMID: 29126152

Article Published Date : Nov 07, 2017

Study Type : Meta Analysis, Review

Additional Links

Diseases : Prostate Cancer

Additional Keywords : Risk Factors

Anti Therapeutic Actions : Shift Work

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The present meta-analysis showed that intake of vitamin C from food was inversely associated with prostate cancer risk. Dec 31, 2014

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Pubmed Data : J Cancer. 2015 ;6(9):913-21. Epub 2015 Jul 28. PMID: 26284143

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Pubmed Data : Phytother Res. 2015 Jan ;29(1):40-2. Epub 2014 Sep 9. PMID: 25205619

Article Published Date : Dec 31, 2014

Study Type : Human Study

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Substances : Nexrutine (Phellodendrom)

Diseases : Prostate Cancer

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Plant Extracts

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The clinical cases presented here reinforce the hypothesis that GcMAF could become part of anticancer immunotherapeutic regimens.Jul 31, 2013

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Pubmed Data : Oncoimmunology. 2013 Aug 1 ;2(8):e25769. Epub 2013 Jul 29. PMID: 24179708

Pubmed Data : Eur Urol. 2005 Dec;48(6):922-30; discussion 930-1. Epub 2005 Oct 17. PMID: 16263208

Article Published Date : Dec 01, 2005

Study Type : Human Study

Additional Links

Substances : Antioxidant formulas, Isoflavones, Lycopene, Milk Thistle, Soy

Diseases : Prostate: PSA Doubling, Prostate Cancer

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A diet rich in healthy plant foods and especially total or raw vegetable may protect against prostate cancer.Jan 26, 2017

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Pubmed Data : Prostate Cancer Prostatic Dis. 2019 Oct 14. Epub 2019 Oct 14. PMID: 31611635

Article Published Date : Oct 13, 2019

Study Type : Human Study

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Diseases : Prostate Cancer

Therapeutic Actions : Cryotherapy

Pharmacological Actions : Chemotherapeutic

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A polyphenol-rich whole food supplement significantly effected the rate of PSA progression among men with prostate cancer.Mar 10, 2014

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Pubmed Data : Nutrients. 2021 Jan 16 ;13(1). Epub 2021 Jan 16. PMID: 33467042

Article Published Date : Jan 15, 2021

Study Type : Human Study

Additional Links

Diseases : Prostate Cancer

Therapeutic Actions : Dietary Modification: Mediterranean Diet, Exercise

Pharmacological Actions : Chemotherapeutic

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After 14 to 25 weekly administrations of GcMAF all patients had very low serum Nagalase levels equivalent to those of healthy control, indicating that these patients are tumor-free.Jun 30, 2008

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Pubmed Data : Transl Oncol. 2008 Jul ;1(2):65-72. PMID: 18633461

Article Published Date : Jun 30, 2008

Study Type : Human Study

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Substances : Gc protein-derived macrophage activating factor (GcMAF)

Diseases : Prostate Cancer

Pharmacological Actions : Immunomodulatory

Additional Keywords : Significant Treatment Outcome

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Allium vegetables are related to decreased risk of prostate cancer. Dec 31, 2012

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Pubmed Data : J Natl Cancer Inst. 2009 Mar 18;101(6):432-5. Epub 2009 Mar 10. PMID: 19276452

Article Published Date : Mar 18, 2009

Study Type : Human Study

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Substances : Folic Acid

Diseases : Prostate Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Whole Food Nutrients are Superior to their Synthetic Equivalents

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Dietary intakes of alpha and delta tocopherol were inversely associated with prostate cancer aggressiveness.Aug 31, 2015

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Pubmed Data : Prostate. 2015 Sep ;75(13):1419-35. Epub 2015 Jun 5. PMID: 26053590

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Pubmed Data : PLoS One. 2013 ;8(7):e67579. Epub 2013 Jul 5. PMID: 23861774

Article Published Date : Dec 31, 2012

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Pubmed Data : Oncol Rep. 2018 Jan ;39(1):417-424. Epub 2017 Nov 13. PMID: 29138841

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Iodine

Diseases : Prostate Cancer

Pharmacological Actions : Chemotherapeutic, Immunomodulatory

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Evidence of an inhibitory effect of diet and exercise on prostate cancer cell growth.Aug 31, 2001

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Pubmed Data : J Urol. 2001 Sep ;166(3):1185-9. PMID: 11490320

Article Published Date : Aug 31, 2001

Pubmed Data : Complement Ther Med. 2018 Aug ;39:14-18. Epub 2018 May 15. PMID: 30012385

Article Published Date : Jul 31, 2018

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Pubmed Data : J Med Food. 2013 Apr ;16(4):357-60. PMID: 23566060

Article Published Date : Mar 31, 2013

Study Type : Human Study

Additional Links

Substances : Enterolactone, Flaxseed, Lignans

Diseases : Prostate Cancer, Prostate Cancer: Prevention

Pharmacological Actions : Antiproliferative , Chemopreventive, Vascular Endothelial Growth Factor A Inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

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Flower pollen extract in association with vitamins versus Serenoa repens in chronic prostatitis/chronic Pelvic pain syndrome.Dec 31, 2018

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Pubmed Data : Int J Cancer. 2019 Sep 4. Epub 2019 Sep 4. PMID: 31486077

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Low blood Mg levels and a high Ca/Mg ratio were significantly associated with high-grade prostate cancer.Jan 01, 2011

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Pubmed Data : PLoS One. 2011 ;6(4):e18237. Epub 2011 Apr 25. PMID: 21541018

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Prostate Cancer

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Low vitamin D status is associated with inflammation in patients with prostate cancer.Mar 27, 2017

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Pubmed Data : Oncotarget. 2017 Mar 28 ;8(13):22076-22085. PMID: 28423553

Article Published Date : Mar 27, 2017

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : C-Reactive Protein, Inflammation, Prostate Cancer, Vitamin D Deficiency

Additional Keywords : Risk Factors

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Men with small prostates at the time of implant had a 33% higher risk of all-cause mortality. Apr 01, 2011

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Pubmed Data : Int J Radiat Oncol Biol Phys. 2011 Apr 1 ;79(5):1318-22. Epub 2010 Jun 3. PMID: 20605366

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Pubmed Data : Arch Ital Urol Androl. 2019 Jul 2 ;91(2). Epub 2019 Jul 2. PMID: 31266276

Article Published Date : Jul 01, 2019

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Pubmed Data : Environ Res. 2019 Nov 8:108902. Epub 2019 Nov 8. PMID: 31785779

Article Published Date : Nov 07, 2019

Study Type : Human Study

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Diseases : Obesity, Phthalate Toxicity , Prostate Cancer

Additional Keywords : Increased Risk

Problem Substances : Phthalates

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Pomegranate juice prolongs PSA doubling time, inhibits cell proliferation and increases apoptosis in men with prostate cancer. Feb 01, 2007

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Pubmed Data : Forsch Komplementmed. 2007 Feb;14(1):39-44. Epub 2007 Mar 6. PMID: 16818701

Article Published Date : Feb 01, 2007

Study Type : Human Study

Additional Links

Substances : Pomegranate

Diseases : Prostate: PSA Doubling, Prostate Cancer

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POMx treatment significantly increased the PSA doubling time by over 6 months in both treatment arms.May 19, 2011

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Pubmed Data : Prostate. 2010 Aug 26. Epub 2010 Aug 26. PMID: 20799287

Article Published Date : Aug 26, 2010

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Pubmed Data : Int J Environ Res Public Health. 2011 Sep ;8(9):3579-90. Epub 2011 Sep 2. PMID: 22016704

Article Published Date : Sep 01, 2011

Study Type : Human Study

Additional Links

Diseases : Mesothelioma, Prostate Cancer, Respiratory Cancers

Problem Substances : 2,4-Dichlorophenoxyacetic acid

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Vitamin E supplementation is associated with a statistically significant reduction in the incidence of prostate cancer. Nov 01, 2007

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Pubmed Data : Ann Saudi Med. 2007 Nov-Dec;27(6):409-14. PMID: 18059122

Article Published Date : Nov 01, 2007

Pubmed Data : Clin Oncol (R Coll Radiol). 1991 Sep;3(5):288-90. PMID: 1931775

Article Published Date : Sep 01, 1991

Study Type : Human: Case Report

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Diseases : Leukemia: Acute myelogenous leukemia (AML) , Myelofibrosis, Prostate Cancer, Radiation Induced Illness

Anti Therapeutic Actions : Radiotherapy

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A high-fat diet containing whole walnuts (Juglans regia) reduces tumour size and growth in an animal model. Jan 16, 2012

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Pubmed Data : Br J Nutr. 2012 Jan 16:1-9. Epub 2012 Jan 16. PMID: 22244053

Aerobic training and green tea extract protect against N-Methyl-N-nitrosourea-induced prostate cancer.May 28, 2019

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Pubmed Data : Med Sci Sports Exerc. 2019 May 29. Epub 2019 May 29. PMID: 31157709

Article Published Date : May 28, 2019

Study Type : Animal Study

Additional Links

Substances : Green Tea

Diseases : Prostate Cancer

Therapeutic Actions : Exercise: Aerobic

Pharmacological Actions : Chemopreventive, NF-kappaB Inhibitor

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Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo.Sep 30, 2003

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Pubmed Data : Carcinogenesis. 2003 Oct ;24(10):1665-70. Epub 2003 Aug 1. PMID: 12896904

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Pubmed Data : Indian J Biochem Biophys. 2012 Dec ;49(6):451-7. PMID: 23350280

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Pubmed Data : Mar Drugs. 2017 Mar 8 ;15(3). Epub 2017 Mar 8. PMID: 28282880

Article Published Date : Mar 07, 2017

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, MicroRNA modulator

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Banana peel extract suppresses prostate gland enlargement in testosterone-treated mice. Jul 01, 2005

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Pubmed Data : Dermatol Surg. 2005 Jul;31(7 Pt 2):855-60; discussion 860. PMID: 19734683

Article Published Date : Jul 01, 2005

Study Type : Animal Study

Additional Links

Substances : Banana, Banana Peel

Diseases : Prostate Enlargement, Prostatic Hyperplasia: Benign, Testosterone-Induced

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Benzyl isothiocyanate inhibits prostate cancer development.Jan 21, 2016

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Pubmed Data : Int J Mol Sci. 2016 02 22 ;17(2):264. Epub 2016 Feb 22. PMID: 26907265

Article Published Date : Jan 21, 2016

Study Type : Animal Study

Additional Links

Substances : Benzyl isothiocyanate

Diseases : Prostate Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Cell cycle arrest, Chemopreventive

Additional Keywords : Isothiocyanates

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Bioactive soybean components inhibit the growth and metastasis of androgen-sensitive human prostate tumors in miceOct 01, 2002

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Pubmed Data : Prostate. 2002 Oct 1;53(2):143-53. PMID: 12242729

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Pubmed Data : Pharm Res. 2009 Oct;26(10):2324-31. Epub 2009 Aug 8. PMID: 19669099

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Pubmed Data : Int J Cancer. 2009 Jul 1;125(1):1-8. PMID: 19326431

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin, Resveratrol

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Natural Substance Synergy, Stilbenes

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Combining green tea polyphenols and quercetin significantly enhanced the antiproliferative and proapoptotic effect in vivo. Dec 31, 2013

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Pubmed Data : J Nutr Biochem. 2014 Jan ;25(1):73-80. Epub 2013 Oct 10. PMID: 24314868

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Green Tea, Quercetin

Diseases : Prostate Cancer, Prostate Cancer: Prevention

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemopreventive

Additional Keywords : Bioavailability, Multidrug Resistance, Natural Substance Synergy

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Compounds contained with Phellodendron amurense inhibits proliferation of cancer cells in the transgenic mouse model of prostate cancer.Dec 23, 2008

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Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:2951428. Epub 2019 Jul 17. PMID: 31391857

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Dandelion , Lemongrass

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy, Selective Cytotoxicity

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Daytime blue light enhances the nighttime circadian melatonin inhibition of human prostate cancer growth.Dec 31, 2014

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Pubmed Data : Comp Med. 2015 ;65(6):473-85. PMID: 26678364

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Pubmed Data : J Appl Physiol (1985). 2004 Feb ;96(2):450-4. PMID: 14715676

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Pubmed Data : Andrology. 2019 Dec 26. Epub 2019 Dec 26. PMID: 31880092

Article Published Date : Dec 25, 2019

Study Type : Animal Study

Additional Links

Substances : Lycopene

Diseases : Chronic Pelvic Pain Syndrome, Prostatitis: Chronic

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Nrf2 activation

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Lycopene exerts anti-inflammatory effect to inhibit prostate cancer progression.Sep 06, 2018

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Pubmed Data : Cancer Res. 2009 Jan 15 ;69(2):518-25. PMID: 19147565

Article Published Date : Jan 14, 2009

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Garcinia dulcis

Diseases : Prostate Cancer

Pharmacological Actions : Anti-Angiogenic, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Dose Response

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Myricetin effectively represses the malignant progression of prostate cancer.Jul 24, 2018

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Pubmed Data : Cell Physiol Biochem. 2018 Jul 25 ;48(3):1230-1244. Epub 2018 Jul 25. PMID: 30045021

Pubmed Data : Med Princ Pract. 2008;17(2):131-5. Epub 2008 Feb 19. PMID: 9687986

Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis.Nov 01, 2008

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Pubmed Data : Clin Cancer Res. 2008 Nov 1;14(21):6855-66. PMID: 18980980

Article Published Date : Nov 01, 2008

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Prostate Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

Additional Keywords : Drug-Plant-Vitamin Synergies

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View the Evidence: 879 Abstracts with Prostatic Diseases Research

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Coffee consumption and risk of prostate cancer: a systematic review and meta-analysis.Jan 10, 2021

Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.Sep 25, 2016

Cruciferous vegetables intake is related to the decreased risk of prostate cancer.Jan 31, 2012

Evidence exists indicating that Brassica vegetables reduce prostate cancer risk.Jan 01, 2002

In this meta-analysis a positive relation between all-NSAID intake and prostate cancer was observed.Dec 31, 2013

Increased dietary and circulating lycopene are associated with reduced prostate cancer risk.Apr 24, 2017

Intake of concentrated green tea catechin preparations may confer a significant protective effect to carriers of early neoplastic lesions in the prostate.Oct 01, 2019

Integrated evidence from this meta-analysis suggests that shift work is significantly associated with an increased risk of prostate cancer.Nov 07, 2017

The present meta-analysis showed that intake of vitamin C from food was inversely associated with prostate cancer risk. Dec 31, 2014

These findings suggest that coffee consumption may be associated with a reduced risk of prostate cancer.Dec 31, 2014

This dose-response meta-analysis demonstrated that higher lycopene consumption was linearly associated with a reduced risk of PC.Jul 31, 2015

This meta-analysis provides strongest evidence supporting that Type 2 diabetes is significantly inversely associated with risk of developing prostate cancer.May 31, 2013

By the end of the neoadjuvant treatment, 81% of the patients had a decline in prostate-specific antigen.Dec 31, 2014

The clinical cases presented here reinforce the hypothesis that GcMAF could become part of anticancer immunotherapeutic regimens.Jul 31, 2013

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients. Jun 01, 2009

A combination of selenium and silymari led to a significant reduction in PSA levels.Dec 14, 2013

A combination of selenium, vitamin E and soy isoflavones reduces PSA levels and ower risk of prostate cancer in men with high-grade intraepithelial neoplasia. Jun 01, 2007

A combination of soy, isoflavones, lycopene, silymarin and antoxidants significantly increases PSA doubling time in men with prostate cancer. Dec 01, 2005

A diet rich in healthy plant foods and especially total or raw vegetable may protect against prostate cancer.Jan 26, 2017

A dietary change towards a mediterranean-style pattern is both achievable and could be beneficial for men with prostate cancer.Dec 31, 2014

A high intake of fish may decrease the risk of prostate cancer death. May 01, 2009

A human clinical study demonstrates that diets rich in cruciferous vegetables may reduce the risk of prostate cancer.Jan 01, 2008

A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro.Aug 01, 2003

A Mediterranean-style diet or DASH diet could help reduce the odds of high aggressive prostate cancer.Sep 04, 2018

A pilot trial of pembrolizumab plus prostatic cryotherapy for men with newly diagnosed oligometastatic hormone-sensitive prostate cancer.Oct 13, 2019

A polyphenol-rich whole food supplement significantly effected the rate of PSA progression among men with prostate cancer.Mar 10, 2014

A swedish flower pollen extract has therapeutic value in treating chronic abacterial prostatitis.Jan 01, 2010

A swedish flower pollen extract has therapeutic value in treating chronic prostatitis and prostatic adenoma.May 01, 2007

A western-style diet may lead to increased risks for prostate cancer, especially aggressive prostate cancer.May 01, 2008

Acupuncture increased natural killer cell levels and reduced other white blood cell parameters supporting the possibility that immunity might be important in the pathophysiology of CP/CPPS.Nov 30, 2014

Adherence to Mediterranean diet, physical activity and survival after prostate cancer diagnosis.Jan 15, 2021

After 14 to 25 weekly administrations of GcMAF all patients had very low serum Nagalase levels equivalent to those of healthy control, indicating that these patients are tumor-free.Jun 30, 2008

Allium vegetables are related to decreased risk of prostate cancer. Dec 31, 2012

Beneficial effects of pollen extract in association with vitamins for pain relief in patients affected by chronic prostatitis/chronic pelvic pain syndrome.Apr 23, 2013

Benign tissue inflammation was positively associated with prostate cancer.Jul 27, 2017

Bisphenol-A exposure and risk of breast and prostate cancer in the Spanish European Prospective Investigation into Cancer and Nutrition study.Aug 15, 2021

Boswellia resin extract and propolis derived polyphenols can reduce genitourinary pain and then improve quality of life of men affected by prostatitis-like symptoms.Jan 13, 2020

Chlordecone exposure increases the risk of prostate cancer.Jul 20, 2010

Consumption of canned and cooked tomatoes may reduce the risk of prostate cancer.Feb 24, 2020

Consumption of sugars from sugar-sweetened beverages was associated with increased risk of prostate cancer.Jul 25, 2018

Cruciferous vegetable consumption was strongly associated with reduced risk of prostate cancer progression.Jun 30, 2012

Curcumin improved total antioxidant capacity and lowered PSA scores. Dec 31, 2015

Daily administration of free sulforaphane shows promise in managing biochemical recurrences in prostate cancer after radical prostatectomy.May 11, 2015

Daily consumption of a powdered cranberry fruit lowered serum PSA in patients with prostate cancer. Nov 09, 2016

Dietary fiber intake might modulate the association between alcohol intake and risk of hormone dependent cancer.May 19, 2015

Dietary folate consumption as reflected in plasma folate and not supplementation with folic acid is inversely associated wtih prostate cancer risk. Mar 18, 2009

Dietary intakes of alpha and delta tocopherol were inversely associated with prostate cancer aggressiveness.Aug 31, 2015

Dietary supplements containing EPA, GLA or CoQ10 may significantly affect serum PSA levels.Nov 29, 2012

Distribution of xenotropic murine leukemia virus-related virus (XMRV) infection in chronic fatigue syndrome and prostate cancer.Jun 30, 2010

Effect of acute exercise on prostate cancer cell growth.Dec 31, 2012

Electroacupuncture has therapeutic value in the treatment of chronic prostatitis and chronic pelvic pain syndrome. May 01, 2009

Ellagic acid therapy reduces chemotherapy induced toxicity, e.g. neutropenia, in hormone refractory prostate cancer patients. Apr 01, 2005

Enhanced activated T cell subsets in prostate cancer patients receiving iodine-125 low-dose-rate prostate brachytherapy.Dec 31, 2017

Evidence of an inhibitory effect of diet and exercise on prostate cancer cell growth.Aug 31, 2001

Fish consumption is associated with a 63% reduction in prostate cancer-specific mortality.Nov 01, 2010

Fish consumption may improve prostate cancer survival rates.Nov 01, 2008

Flavonols and catechins have proved to be the most promising molecules for a potential protective role against prostate cancer.Jul 31, 2018

Flaxseed supplementation and a low-fat diet reduces proliferation of benign prostatic epithelium and PSA. May 01, 2004

Flaxseed supplementation reduces prostate cancer proliferation rates in men presurgery. Dec 01, 2008

Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.Mar 31, 2013

Flower pollen extract in association with vitamins versus Serenoa repens in chronic prostatitis/chronic Pelvic pain syndrome.Dec 31, 2018

Genistein and daidzein consumption are associated with a lower risk of prostate cancer. Aug 01, 2009

Genistein has therapeutic value in reducing PSA levels in men with prostate cancer. Feb 01, 2004

Genistein may block metastasis and mortality in prostate cancer through blocking the activation of MEK4 and MMP-2 expression. Aug 19, 2009

Green tea induced changes in NFκB and systemic oxidation, and uptake of GT polyphenols in prostate tissue they may have a role in prostate cancer prevention and treatment.Mar 31, 2015

Habitual mushroom intake might help to prevent prostate cancer.Sep 03, 2019

Higher concentrations of circulating genistein may reduce the risk of prostate cancer.Jun 02, 2009

Higher fruit intake was associated with a small reduction in prostate cancer risk.Apr 16, 2017

Higher levels of plasma carboxymethyllysine were associated with increased risk of prostate cancer.Sep 30, 2015

Higher vitamin E status increases overall prostate cancer survival. May 01, 2009

Hypermethylation of IFN and ICAM-1 may play important roles in early carcinogenesis, particularly that of prostate cancer.Aug 10, 2015

Increased exposure to sunlight may reduce prostate cancer risk. Sep 15, 2009

Prostatic Diseases

View the Evidence:
879 Abstracts with Prostatic Diseases Research