Pulmonary Fibrosis

Name	AC	CK
Flavonoids	8	33
Curcumin	13	25
Pterostilbene	3	23
Astragaloside	8	16
Ginkgo biloba	4	16
NAC (N-acetyl-L-cysteine)	5	16
Pycnogenol (Pine Bark)	2	12
Vitamin D	2	12
Sulforaphane	2	11
Fiber	1	10
Fruit: All	1	10
Resveratrol	6	9
Tanshinone IIA	7	9
Ginsenosides	5	7
Fucoidan	2	5
Quercetin	3	5
Chlorogenic Acid	2	4
Fish Oil	2	4
Mangiferin	2	4
Nobiletin	2	4
Taurine	2	4
EGCG (Epigallocatechin gallate)	2	3
Kaempferol	2	3
Panax Notoginseng	2	3
Puerarin	3	3
Alpha-Lipoic Acid	1	2
Angelica	1	2
Arctigenin	2	2
Beta Sitosterol	1	2
Biochanin A	1	2
Borage Oil	1	2
Carnitine	1	2
Chinese Herbal Formula: Decoction for Strengthening Qi and Replenishing Lung (DSQRL)	1	2
Chokeberry	1	2
Cordyceps sinensis	1	2
Corn Silk	1	2
Cyanidin 3-glucoside	1	2
Diosgenin	1	2
EPA (Eicosapentaenoic Acid)	1	2
Emodin	1	2
Fenugreek	1	2
Ferulic acid	1	2
Garlic	1	2
Gingerol	1	2
Grape Seed Extract	1	2
Gymnadenia conopsea	1	2
Honokiol	1	2
Hu Zhang (Polygonum cuspidatum)	1	2
Hydroxytyrosol	1	2
Icariin	1	2
Lecithin	1	2
Lignans	1	2
Naringenin	1	2
Niacin	1	2
Orange: Mandarin	1	2
Organosulfur Compounds	1	2
Red Sage	2	2
Safflower	1	2
Sinomenine	1	2
St. Johns Wort	1	2
Superoxide dismutase	1	2
Tannic Acid	1	2
Thymoquinone	1	2
Vitamin E	1	2
Artesunate	1	1
Astaxanthin	1	1
Baicalein	1	1
Basil	1	1
Berberine	1	1
Blueberry	1	1
Catechin	1	1
Citrus naringin	1	1
Ginseng	1	1
Ginseng (Korean)	1	1
Glycyrrhizin	1	1
Green Tea	1	1
Guduchi	1	1
Hesperidin	1	1
Ligusticum wallichii	1	1
Magnolol	1	1
Melatonin	1	1
Neem	1	1
Piceatannol	1	1
Saikosaponin	1	1
Salvia miltiorrhiza	1	1
Silymarin	1	1
Turmeric	1	1

Name	AC	CK
Paraquat	5	8
Polystyrene nanoparticles	2	3
Electronic Cigarettes	1	2
Nano Plastic-and Micro-Particles	1	2
Perchlorate	1	2
Pesticides	1	2

Name	AC	CK
Exercise: Aerobic	1	20
Therapeutic Breathing	1	20
Dietary Modification: Low Fat Diet	1	10
Dietary Modification: Vegetarian	1	10
Exercise: Inspiratory Muscle Training	1	10
Moxibustion	1	10
Photobiomodulation	1	2

Name	AC	CK	Focus
Vaccination: All	1	3
Vaccination: Influenza	1	3

[+]

Protective role of baicalin in the dynamic progression of lung injury to idiopathic pulmonary fibrosis.May 31, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2023 ;14:1141800. Epub 2023 Mar 14. PMID: 36998607

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : Lignans

Diseases : Pulmonary Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Astragaloside IV inhibits epithelial-mesenchymal transition and pulmonary fibrosis.Feb 29, 2024

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Pubmed Data : Gene. 2024 Mar 1 ;897:148040. Epub 2023 Dec 6. PMID: 38065426

Article Published Date : Feb 29, 2024

Study Type : Animal Study

Additional Links

Substances : Astragaloside

Diseases : Pulmonary Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Astragaloside IV inhibits idiopathic pulmonary fibrosis.Feb 28, 2024

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2024 Feb 29 ;70(2):128-136. Epub 2024 Feb 29. PMID: 38430031

Article Published Date : Feb 28, 2024

Study Type : Animal Study

Additional Links

Substances : Astragaloside

Diseases : Pulmonary Fibrosis

Pharmacological Actions : Anti-Fibrotic

Additional Keywords : MicroRNA-21

[+]

Curcumin is more effective than prednisone at suppressing bleomycin-induced pulmonary fibrosis in rats. May 01, 2008

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Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2008 May;26(5):257-61. PMID: 18727865

Article Published Date : May 01, 2008

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Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2008 Jun;33(12):1434-8. PMID: 18837350

Article Published Date : Jun 01, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis

[+]

Curcumin was beneficial in acute lung injury and lung fibrosis.Aug 22, 2019

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Pubmed Data : Endocr Metab Immune Disord Drug Targets. 2019 Aug 23. Epub 2019 Aug 23. PMID: 31441735

Article Published Date : Aug 22, 2019

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Lung Injury: Acute, Pulmonary Fibrosis, Pulmonary Fibrosis: Bleomycin-Induced

Pharmacological Actions : Anti-Fibrotic

[+]

Cyanidin-3-galactoside from Aronia melanocarpa ameliorates silica-induced pulmonary fibrosis.Jul 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Chem Biol Interact. 2009 Jul 15;180(2):271-80. Epub 2009 Mar 20. PMID: 19497426

Article Published Date : Jul 15, 2009

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis

[+]

Exploring the mechanism whereby sinensetin delays the progression of pulmonary fibrosis.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2021 ;12:693061. Epub 2021 Jun 18. PMID: 34220517

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Flavonoids

Diseases : Pulmonary Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation

[+]

Ferulic acid combined with astragaloside IV reduced the degree of pulmonary fibrosis.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:8845798. Epub 2021 Mar 2. PMID: 33763150

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Astragaloside, Ferulic acid

Diseases : Pulmonary Fibrosis

Pharmacological Actions : Anti-Fibrotic

Additional Keywords : Natural Substance Synergy

[+]

Fish oil protects against inflammation and fibrosis in the lung and liver. Jun 14, 2002

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Pubmed Data : Toxicology. 2002 Jun 14;175(1-3):1-13. PMID: 12049831

Article Published Date : Jun 14, 2002

Study Type : Animal Study

Additional Links

Substances : Fish Oil

Diseases : Liver Fibrosis, Pulmonary Fibrosis

[+]

Galangin ameliorated pulmonary fibrosis in vivo and in vitro by regulating epithelial-mesenchymal transition.Sep 30, 2020

Pubmed Data : Toxicol Lett. 2020 Oct 15 ;333:170-183. Epub 2020 Aug 11. PMID: 32795487

Article Published Date : Oct 14, 2020

Study Type : Animal Study

Additional Links

Diseases : Herbicide Toxicity, Pulmonary Fibrosis

Problem Substances : Paraquat

[+]

Perchlorate can induce pulmonary fibrosis in the rabbit lung.Oct 12, 2010

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Pubmed Data : Toxicol Ind Health. 2010 Oct 12. Epub 2010 Oct 12. PMID: 20937628

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Ginseng Res. 2023 Jan ;47(1):97-105. Epub 2022 Jul 5. PMID: 36644392

Article Published Date : Dec 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Asthma, Chronic Obstructive Pulmonary Disease, Pulmonary Fibrosis, Respiratory Diseases

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Aerosol inhalation of total ginsenosides repairs acute lung injury and inhibits pulmonary fibrosis.Jul 13, 2024

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Pubmed Data : Phytomedicine. 2024 Jul 14 ;133:155871. Epub 2024 Jul 14. PMID: 39098168

Article Published Date : Jul 13, 2024

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Pulmonary Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents

[+]

Click here to read the entire abstract

Pubmed Data : Pharmazie. 2021 Feb 25 ;76(2):97-102. PMID: 33714286

Article Published Date : Feb 24, 2021

Study Type : In Vitro Study

Additional Links

Substances : Astragaloside

Diseases : Pulmonary Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents

[+]

Blueberry juice attenuates pulmonary fibrosis via blocking the TGF-β1/Smad signaling pathway.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Immunol. 2003 Apr 15;170(8):4335-41. PMID: 12682270

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Puerarin regulated the proliferation and apoptosis of pulmonary fibrosis cells.Aug 30, 2019

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Pubmed Data : Med Sci Monit. 2019 Aug 31 ;25:6523-6531. Epub 2019 Aug 31. PMID: 31471534

Article Published Date : Aug 30, 2019

Study Type : In Vitro Study

Additional Links

Substances : Puerarin

Diseases : Acute Respiratory Distress Syndrome, Pulmonary Fibrosis

Pharmacological Actions : Anti-Fibrotic, Interleukin-2 Downregulation, Interleukin-4 downregulation, Transforming growth factor beta (TGF-β) inhibitor

[+]

Red ginseng extract might be a potential material that can regulate chronic PM2.5-induced lung and brain cognitive dysfunction.Aug 25, 2023

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Pubmed Data : Int J Mol Sci. 2023 Aug 26 ;24(17). Epub 2023 Aug 26. PMID: 37686071

Pubmed Data : Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2019 Mar ;35(3):256-261. PMID: 31030720

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Biomed Pharmacother. 2020 Dec ;132:110827. Epub 2020 Oct 13. PMID: 33065391

Article Published Date : Nov 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Melatonin

Diseases : Lipopolysaccharide-Induced Toxicity, Pulmonary Fibrosis

Pharmacological Actions : Antioxidants, Nrf2 activation

[+]

Urban airborne PM2.5 induces pulmonary fibrosis through triggering glycolysis and subsequent modification of histone lactylation in macrophages.Mar 14, 2024

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ecotoxicol Environ Saf. 2024 Mar 15 ;273:116162. Epub 2024 Mar 8. PMID: 38458067

Article Published Date : Mar 14, 2024

Study Type : In Vitro Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Pulmonary Fibrosis

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View the Evidence: 148 Abstracts with Pulmonary Fibrosis Research

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Breathing exercises complements exercise training towards improved dyspnea and health-related quality of life in patients with Idiopathic pulmonary fibrosis.Feb 29, 2020

Protective role of baicalin in the dynamic progression of lung injury to idiopathic pulmonary fibrosis.May 31, 2023

The effect of pterostilbene and its active ingredients on experimental pulmonary fibrosis in asthma.Sep 30, 2022

Adding inspiratory muscle training increases effectiveness of pulmonary rehabilitation in idiopathic pulmonary fibrosis patients.Jan 01, 2008

Decreased serum 1,25(OH)2D3 is associated with an increased risk of acute exacerbation for patients with idiopathic pulmonary fibrosis.Dec 31, 2021

Dietary fat and meat intake are correlated with increased risk for idiopathic pulmonary fibrosis. Mar 01, 2006

Ginkgo is effective in treating pulmonary interstitial fibrosis.Mar 01, 2005

Moxibustion can significantly suppress the expression of TGF-beta1mRNA in the pulmonary tissue in the rat of bleomycin-induced pulmonary fibrosis.Nov 01, 2005

NAC could ameliorate COPD-induced pulmonary fibrosis by promoting immune response.Jan 02, 2021

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects. Mar 01, 2009

Pycnogenol®-Centellicum® supplementation improves lung fibrosis and Post-Covid-19 lung healing.Jun 27, 2021

Soluble fiber and fruit intake may confer protection against the development of idiopathic pulmonary fibrosis (IPF).Nov 01, 2004

A case report of idiopathic pulmonary fibrosis after the H1N1 influenza vaccine.Jan 01, 2010

Astragaloside IV protects against lung injury and pulmonary fibrosis in COPD.Sep 07, 2023

Low molecular weight fucoidan inhibits pulmonary fibrosis.Dec 31, 2021

Tanshinone IIA regulates Keap1/Nrf2 signal pathway by activating sestrin2 to restrain pulmonary fibrosis.Oct 28, 2022

These findings suggest that astragaloside might treat pulmonary fibrosis.Sep 30, 2022

6-Gingerol, a functional polyphenol of ginger, reduces pulmonary fibrosis by activating Sirtuin1.Dec 31, 2021

Alpha lipoic acid attenuates bleomycin-induced pulmonary fibrosis in mice. Jun 01, 2007

An extract of Mandarin Orange demonstrates anti-pulmonary fibrosis effects. Oct 29, 2009

Angelica sinesis inhibits the progress of radiation-induced pulmonary fibrosis. Mar 01, 2007

Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis.Dec 31, 2022

Astragaloside IV inhibits epithelial-mesenchymal transition and pulmonary fibrosis.Feb 29, 2024

Astragaloside IV inhibits idiopathic pulmonary fibrosis.Feb 28, 2024

Astragaloside IV restrains pulmonary fibrosis progression.Feb 29, 2024

Beta-sitosterol can be used to attenuate pulmonary fibrosis through suppression of EMT by inhibiting the TGF-β1/Snail pathway.Sep 03, 2019

Biochanin-A ameliorates pulmonary fibrosis.Jul 31, 2020

Chlorogenic acid inhibits progressive pulmonary fibrosis.Jan 31, 2024

Chlorogenic acid protective effects on paraquat-induced pulmonary oxidative damage and fibrosis.Apr 02, 2023

Cigarette smoke exposure combined with lipopolysaccharides induced pulmonary fibrosis in mice.Jul 31, 2019

Cordyceps alleviates bleomycin-induced alveolitis and fibrosis. Dec 01, 2007

Curcumin (from Turmeric) reduces oxidative injury associated with idiopathic pulmonary fibrosis.Apr 01, 2006

Curcumin can alleviate alveolitis and pulmonary fibrosis induced by bleomycin in rats.Mar 01, 2007

Curcumin can induce apoptosis of pulmonary fibroblasts in rats with bleomycin-induced pulmonary fibrosis.Jan 01, 2009

Curcumin has a similar effect to hydrocortisone in preventing bleomycin-induced pulmonary fibrosis. Jun 13, 2007

Curcumin inhibits bleomycin-induced pulmonary fibrosis in rats.Sep 01, 2000

Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury.Jan 08, 2010

Curcumin is more effective than prednisone at suppressing bleomycin-induced pulmonary fibrosis in rats. May 01, 2008

Curcumin may play its therapetuic role by leveling down the content of extracellular matrix in rats with pulmonary fibrosis induced by bleomycin.Apr 01, 2006

Curcumin protects against amiodarone-induced pulmonary fibrosis in rats.Aug 01, 2003

Curcumin protects against bleomycin-induced damages in pulmonary functions in ratsJun 01, 2008

Curcumin was beneficial in acute lung injury and lung fibrosis.Aug 22, 2019

Cyanidin-3-galactoside from Aronia melanocarpa ameliorates silica-induced pulmonary fibrosis.Jul 31, 2022

Diallyl disulfide can serve as a potential candidate or dietary nutraceutical supplement for the treatment of pulmonary fibrosis.Jun 11, 2024

Diallyl sulfide reduced the bleomycin-induced activation of inducible nitric oxide synthase (iNOS) and nuclear factor kappa-B (NF-kappaB) and decreased the augmented levels of the early inflammatory cytokines, tumour necrosis factor-alpha (TNF-alpha) and Jun 06, 2008

Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice.May 01, 2010

Dietary fish oil and fish and borage oil suppress intrapulmonary inflammation and attenuate pulmonary neutrophil accumulation in endotoxic rats.Jul 01, 1997

Effect of baicalin on expression of fibrogenic factors TGF-β1, mmp2 and timp2 in tissue of mice with pulmonary fibrosis.Nov 30, 2020

EGCG exhibits anti-fibrotic effects in a rat model of pulmonary fibrosis. Jul 15, 2009

Exploring the mechanism whereby sinensetin delays the progression of pulmonary fibrosis.Dec 31, 2020

Ferulic acid combined with astragaloside IV reduced the degree of pulmonary fibrosis.Dec 31, 2020

Fish oil protects against inflammation and fibrosis in the lung and liver. Jun 14, 2002

Galangin ameliorated pulmonary fibrosis in vivo and in vitro by regulating epithelial-mesenchymal transition.Sep 30, 2020

Ginkgo biloba extract 50 (GBE50) exerts antifibrotic and antioxidant effects on pulmonary fibrosis.Nov 15, 2023

Ginkgo biloba has a positive effect on pulmonary interstitial fibrosis in ratsJun 01, 2000

Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.Jun 30, 2023

Grape seed extract attenuates silica-induced pulmonary fibrosis in rats. Aug 01, 2009

Gymnadenia conopsea can ameliorate the silica-induced pulmonary fibrosis by increasing the activities of antioxidase and alleviating the damage of lipid peroxidation to the lungs.Jan 01, 2007

Honokiol ameliorates pulmonary fibrosis.Feb 03, 2020

Hu Zhang (Polygonum cuspidatum), a rich source of resveratrol, inhibits the expression of inflammation in lung fibroblasts and reduces alveolitis and pulmonary fibrosis. Jun 01, 2009

Hydroxytyrosol alleviates methotrexate-induced pulmonary fibrosis in rats.Dec 31, 2023

Hyperforin, a compound found within St. John's wort, has powerful anti-inflammatory therapeutic potential in reducing lung fibrosis. May 01, 2007

Kaempferol inhibits the progression of silica-induced pulmonary fibrosis.Sep 26, 2019

L-carnitine and ginkgo biloba extract exhibits a protective agent in an animal model of bleomycin-induced lung fibrosis Jun 01, 2002

Lecithinized superoxide dismutase has protective activity against bleomycin-induced pulmonary fibrosis. Dec 24, 2009

Long-term exposure to PM2.5 aggravates pulmonary fibrosis and acute lung injury.Aug 21, 2022

Low molecular weight fucoidan attenuating pulmonary fibrosis.Nov 30, 2021

Low-level laser therapy attenuates lung inflammation and airway remodeling in a murine model of idiopathic pulmonary fibrosis.Dec 31, 2019

Mangiferin alleviates diabetic pulmonary fibrosis in mice.Apr 30, 2024

N-Acetylcysteine decreases lung inflammation and fibrosis by modulating ROS and Nrf2 in mice model exposed to particulate matter.Jun 02, 2022

N-acetylcysteine therapeutically protects against pulmonary fibrosis in a mouse model of silicosis.Jul 30, 2019

Nano-enabled delivery of diosgenin and emodin ameliorates respirable silica dust-induced pulmonary fibrosis silicosis.Jun 30, 2024

Pulmonary Fibrosis

View the Evidence:
148 Abstracts with Pulmonary Fibrosis Research