Pulmonary Fibrosis: Bleomycin-Induced

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45 Substances Researched for Pulmonary Fibrosis: Bleomycin-Induced
NameACCKFocus
Chamomile24Locked
Crocin24Locked
Mangiferin24Locked
Nigella sativa (aka Black Seed)24Locked
Safflower24Locked
Tanshinone IIA24Locked
Thymoquinone24Locked
Resveratrol23Locked
Astragaloside12Locked
Babchi12Locked
Bee Propolis12Locked
Betulinic acid12Locked
Carnosic Acid12Locked
Celastrol12Locked
Chrysin12Locked
Curcumin12Locked
Fisetin12Locked
Flaxseed12Locked
Fucoidan12Locked
Fucoxanthin 12Locked
Garlic: Aged12Locked
Ginsenosides12Locked
Gotu Kola12Locked
Grape Seed Extract12Locked
Hesperidin12Locked
Licorice12Locked
Ligustrazine12Locked
Magnolol12Locked
Myricetin12Locked
Myrtle12Locked
Oridonin12Locked
Paeoniflorin12Locked
Paeonol12Locked
Parthenolide12Locked
Quercetin12Locked
Reishi Mushroom12Locked
Rosemary12Locked
Royal Jelly12Locked
Sage12Locked
Salvia miltiorrhiza12Locked
Spermidine 12Locked
Walnut12Locked
neohesperidin12Locked
Kaempferol11Locked
Mangosteen11Locked
1 Problem Substances Researched for Pulmonary Fibrosis: Bleomycin-Induced
NameACCKFocus
Bleomycin24Locked

View the Evidence:
51 Abstracts with Pulmonary Fibrosis: Bleomycin-Induced Research

[+]

Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.Jun 10, 2020

Pubmed Data : Biochem Pharmacol. 2020 Jun 11 ;178:114097. Epub 2020 Jun 11. PMID: 32535102
Article Published Date : Jun 10, 2020
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents, Heat Shock Protein Down-Regulation, Transforming growth factor beta (TGF-β) inhibitor
[+]

A combination of Chamomile and Anthocyanoside lead to a significant reduction in Bleomycin-induced MDA.Jul 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Arch. 2015 Aug ;69(4):229-31. Epub 2015 Aug 4. PMID: 26543307
Article Published Date : Jul 31, 2015
Study Type : Animal Study
Additional Links
Substances : Chamomile
Diseases : Lipid Peroxidation, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation
[+]

Asiaticoside attenuates bleomycin-induced pulmonary fibrosis.Jun 29, 2020

Pubmed Data : Biochem Biophys Res Commun. 2020 Jun 30 ;527(3):662-667. Epub 2020 May 15. PMID: 32423816
Article Published Date : Jun 29, 2020
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents
[+]

Astragaloside IV improves bleomycin-induced pulmonary fibrosis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:513. Epub 2017 Aug 8. PMID: 28848434
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Astragaloside IV modulates TGF‐β1‐dependent epithelial‐mesenchymal transition in bleomycin‐induced pulmonary fibrosisAug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2018 Sep ;22(9):4354-4365. Epub 2018 Jul 4. PMID: 29971947
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.Dec 31, 2020

Pubmed Data : Phytomedicine. 2021 Jan ;81:153428. Epub 2020 Dec 1. PMID: 33341025
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Betulinic acid
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents, Wnt/β-catenin signaling pathway modulation
[+]

Both rosemary extracts administrated alone or in combination alleviated synergistically lung fibrosis.Oct 15, 2020

Pubmed Data : Nutr Cancer. 2020 Oct 16:1-12. Epub 2020 Oct 16. PMID: 33059466
Article Published Date : Oct 15, 2020
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid, Rosemary
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
Additional Keywords : Natural Substance Synergy
[+]

Celastrol is a novel selective agonist of cannabinoid receptor 2 with anti-inflammatory and anti-fibrotic activity in a mouse model of systemic sclerosis.Jan 31, 2020

Pubmed Data : Phytomedicine. 2020 Feb ;67:153160. Epub 2019 Dec 26. PMID: 31901889
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Celastrol
Diseases : Fibrosis, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Chamomile hydroalcoholic extract may be able to diminish the toxic effects of bleomycin on the lung tissues.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Tanaffos. 2018 Oct ;17(4):264-271. PMID: 31143217
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Chamomile
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

Chrysin mitigates bleomycin-induced pulmonary fibrosis.Oct 08, 2020

Pubmed Data : Int Immunopharmacol. 2020 Oct 9 ;89(Pt A):107011. Epub 2020 Oct 9. PMID: 33045575
Article Published Date : Oct 08, 2020
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis.Aug 25, 2019

Pubmed Data : Life Sci. 2019 Aug 26:116794. Epub 2019 Aug 26. PMID: 31465731
Article Published Date : Aug 25, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Crocin: a protective natural antioxidant against pulmonary fibrosis induced by bleomycin.Jan 28, 2020

Pubmed Data : Pharmacol Rep. 2020 Jan 29. Epub 2020 Jan 29. PMID: 31997260
Article Published Date : Jan 28, 2020
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Chemoprotective Agents
[+]

Curcumin was beneficial in acute lung injury and lung fibrosis.Aug 22, 2019

Pubmed Data : Endocr Metab Immune Disord Drug Targets. 2019 Aug 23. Epub 2019 Aug 23. PMID: 31441735
Article Published Date : Aug 22, 2019
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Lung Injury: Acute, Pulmonary Fibrosis, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

Dietary flaxseed oil protects against bleomycin-induced pulmonary fibrosis in rats.Dec 31, 2011

Pubmed Data : Pulm Med. 2012 ;2012:457031. Epub 2012 Aug 8. PMID: 22919480
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Flaxseed
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced
Problem Substances : Bleomycin
[+]

Fisetin alleviated bleomycin-induced pulmonary fibrosis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:553690. Epub 2020 Dec 14. PMID: 33381023
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Fucoxanthin inhibits profibrotic protein expression in vitro and attenuates bleomycin-induced lung fibrosis in vivo.Sep 14, 2017

Pubmed Data : Eur J Pharmacol. 2017 Sep 15 ;811:199-207. Epub 2017 Jun 19. PMID: 28642129
Article Published Date : Sep 14, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

G. glabra may be suggested for the prevention and treatment of pulmonary fibrosis and inflammation.May 08, 2019

Pubmed Data : Drug Chem Toxicol. 2019 May 9:1-7. Epub 2019 May 9. PMID: 31072167
Article Published Date : May 08, 2019
Study Type : Animal Study
Additional Links
Substances : Licorice
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation
[+]

Grape seed extracts may improve the quality of life of lung fibrosis patients by inhibiting MMP-9 and TGF-β1 expression in the lungs.Mar 11, 2017

Pubmed Data : Toxicol Lett. 2017 Mar 12 ;273:1-9. Epub 2017 Mar 12. PMID: 28300665
Article Published Date : Mar 11, 2017
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Hesperidin ameliorates bleomycin-induced experimental pulmonary fibrosis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EXCLI J. 2019 ;18:723-745. Epub 2019 Aug 29. PMID: 31611754
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hydroxysafflor yellow A attenuates bleomycin-induced pulmonary fibrosis.Mar 31, 2016

Pubmed Data : Phytother Res. 2016 Apr ;30(4):577-87. Epub 2016 Jan 18. PMID: 26777519
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Inhibitory effects of total ginsenoside on bleomycin-induced pulmonary fibrosis in mice.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jun ;114:108851. Epub 2019 Apr 6. PMID: 30965234
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Juglanin alleviates bleomycin-induced lung injury.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Jul ;127:110119. Epub 2020 Apr 7. PMID: 32276127
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Low-molecular-weight fucoidan attenuates bleomycin-induced pulmonary fibrosis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(4):2590-2602. Epub 2019 Apr 15. PMID: 31105865
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Magnolol might be a potent anti-inflammatory and anti-fibrotic agent against bleomycin-induced lung fibrosis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Med. 2015 ;8(9):15450-7. Epub 2015 Sep 15. PMID: 26629034
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Magnolol
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Mangiferin attenuates bleomycin-induced pulmonary fibrosis.Mar 06, 2019

Pubmed Data : J Pharm Pharmacol. 2019 Mar 7. Epub 2019 Mar 7. PMID: 30847938
Article Published Date : Mar 06, 2019
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

Myrtle extract effectively inhibited the inflammation and fibrosis of lung parenchyma in both preventive and therapeutic methods.Sep 30, 2018

Pubmed Data : Drug Chem Toxicol. 2018 Oct ;41(4):408-414. Epub 2018 May 11. PMID: 29747538
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Myrtle
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, Prophylactic Agents
[+]

N. Sativa extract is effective for early and late prevention of pulmonary fibrosis and inflammation. Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2018 May-Jun;8(3):263-275. PMID: 29881712
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

Neohesperidin inhibits TGF-β1/Smad3 signaling and alleviates bleomycin-induced pulmonary fibrosis in mice.Nov 30, 2019

Pubmed Data : Eur J Pharmacol. 2019 Dec 1 ;864:172712. Epub 2019 Oct 2. PMID: 31586469
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents, Transforming growth factor beta (TGF-β) inhibitor
[+]

Nigella sativa oil treatment attenuated the effects of bleomycin induced pulmonary fibrosis.Apr 12, 2017

Pubmed Data : Biomed Pharmacother. 2017 Apr 13 ;90:626-637. Epub 2017 Apr 13. PMID: 28412654
Article Published Date : Apr 12, 2017
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Fibrosis, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Oridonin inhibits myofibroblast differentiation and bleomycin-induced pulmonary fibrosis.Oct 21, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2018 Oct 22 ;24:7548-7555. Epub 2018 Oct 22. PMID: 30347408
Article Published Date : Oct 21, 2018
Study Type : Animal Study
Additional Links
Substances : Oridonin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Transforming growth factor beta (TGF-β) inhibitor
[+]

Paeoniflorin attenuates pulmonary fibrosis by suppressing type I collagen synthesis.Oct 06, 2013

Pubmed Data : J Ethnopharmacol. 2013 Oct 7 ;149(3):825-32. Epub 2013 Aug 22. PMID: 23973787
Article Published Date : Oct 06, 2013
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Parthenolide attenuated bleomycin-induced pulmonary fibrosis.Jan 04, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Respir Res. 2018 06 5 ;19(1):111. Epub 2018 Jun 5. PMID: 29871641
Article Published Date : Jan 04, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Parthenolide
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Polysaccharides from Ganoderma lucidum played a positive protective role in the pulmonary fibrosis.Oct 31, 2016

Pubmed Data : Int J Biol Macromol. 2016 Nov ;92:278-281. Epub 2016 Aug 2. PMID: 27381587
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Polysaccharides
[+]

Prevention of bleomycin-induced pulmonary inflammation and fibrosis in mice by paeonol.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2017 ;8:193. Epub 2017 Mar 31. PMID: 28408888
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants
[+]

Propolis has protective effects against bleomycin induced pulmonary fibrosis.Feb 29, 2016

Pubmed Data : Biotech Histochem. 2016 Mar ;91(3):195-203. Epub 2016 Mar 9. PMID: 26960158
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Bee Propolis
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents
[+]

Protective effect of hydroxysafflor yellow A on bleomycin- induced pulmonary inflammation and fibrosis.Dec 31, 2017

Pubmed Data : Chin J Integr Med. 2018 Jan ;24(1):32-39. Epub 2018 Jan 3. PMID: 29294256
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Psoralen attenuates bleomycin-induced pulmonary fibrosis.Jul 21, 2019

Pubmed Data : Cell Biol Int. 2019 Jul 22. Epub 2019 Jul 22. PMID: 31329322
Article Published Date : Jul 21, 2019
Study Type : Animal Study
Additional Links
Substances : Babchi
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Royal jelly attenuates oxidative damage and fibrosis induced by bleomycin.Jul 20, 2016

Pubmed Data : Can J Physiol Pharmacol. 2016 Jul 21:1-9. Epub 2016 Jul 21. PMID: 27841941
Article Published Date : Jul 20, 2016
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Bleomycin
[+]

S-allyl cysteine may be useful for the prevention or treatment of pulmonary fibrosis.Mar 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Mar 29 ;22(4). Epub 2017 Mar 29. PMID: 28353632
Article Published Date : Mar 28, 2017
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

Salvia miltiorrhiza and ligustrazine is safe and effective in repressing BLM-induced pulmonary fibrosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2018 ;13:36. Epub 2018 Jul 4. PMID: 29997685
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Ligustrazine, Salvia miltiorrhiza
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Salvia officinalis attenuates bleomycin-induced oxidative stress and lung fibrosis in rats.Oct 11, 2019

Pubmed Data : Nutr Cancer. 2019 Oct 12:1-11. Epub 2019 Oct 12. PMID: 31608667
Article Published Date : Oct 11, 2019
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Oxidative Stress, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Antioxidants
[+]

Spermidine attenuates bleomycin-induced lung fibrosis.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Mol Med. 2020 Dec ;52(12):2034-2045. Epub 2020 Dec 14. PMID: 33318630
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Spermidine
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Autophagy Up-regulation, Chemoprotective Agents
[+]

Tanshinone IIA ameliorates the bleomycin-induced endothelial-to-mesenchymal transition.Nov 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 Dec ;77:105968. Epub 2019 Nov 6. PMID: 31704290
Article Published Date : Nov 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Pulmonary Fibrosis: Bleomycin-Induced, Scleroderma: Systemic
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Med Sci. 2014 ;11(6):578-86. Epub 2014 Apr 7. PMID: 24782646
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Inflammation, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

These findings confirmed the anti-inflammatory effects of resveratrol and quercetin in BLM-induced lung damage.Aug 31, 2015

Pubmed Data : Br J Nutr. 2015 Sep ;114(6):853-865. PMID: 26334388
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Mangiferin, Quercetin, Resveratrol
Diseases : Pulmonary Fibrosis, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
[+]

Thymoquinone can be developed as a potential therapeutic modularity in bleomycin-induced lung fibrosis for human use.Feb 12, 2020

Pubmed Data : Exp Lung Res. 2020 Feb 13:1-11. Epub 2020 Feb 13. PMID: 32053036
Article Published Date : Feb 12, 2020
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Chemoprotective Agents, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Thymoquinone-PLGA-PVA nanoparticles ameliorate bleomycin-induced pulmonary fibrosis.Nov 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Animals (Basel). 2019 Nov 11 ;9(11). Epub 2019 Nov 11. PMID: 31717986
Article Published Date : Nov 10, 2019
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Alpha-mangostin ameliorates bleomycin-induced pulmonary fibrosis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:1305. Epub 2019 Nov 13. PMID: 31798444
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Antioxidants
[+]

Kaempferol might improve bleomycin-induced fibrosis by reducing oxidative stress, inflammation, and oxidative cellular damage.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dermatol Sci. 2019 Oct ;96(1):8-17. Epub 2019 Aug 16. PMID: 31447184
Article Published Date : Sep 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Nimbolide as a potent anti-fibrotic agent.Sep 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 Oct ;75:105755. Epub 2019 Aug 1. PMID: 31377591
Article Published Date : Sep 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Neem
Diseases : Pulmonary Fibrosis, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Resveratrol inhibits pulmonary fibrosis by regulating miR-21 through MAPK/AP-1 pathways.May 25, 2018

Pubmed Data : Biomed Pharmacother. 2018 May 26 ;105:37-44. Epub 2018 May 26. PMID: 29843043
Article Published Date : May 25, 2018
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, MicroRNA modulator

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