Radiation Induced Illness: Mucositis

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25 Substances Researched for Radiation Induced Illness: Mucositis
NameACCKFocus
Honey891Locked
Turmeric440Locked
Vitamin E324Locked
Vitamin A120Locked
Aloe Vera414Locked
Bee Propolis314Locked
Curcumin314Locked
Nigella sativa (aka Black Seed)212Locked
EGCG (Epigallocatechin gallate)110Locked
Glutamine110Locked
Licorice110Locked
Pomegranate110Locked
Riboflavin (Vitamin B-2)110Locked
Royal Jelly110Locked
Salt110Locked
Silymarin110Locked
Sodium Bicarbonate110Locked
Thyme110Locked
Vitamin C110Locked
Woad110Locked
Zataria multiflora110Locked
Lycopene12Locked
Palmitoylethanolamide 12Locked
Pectin12Locked
Chamomile11Locked
1 Therapeutic Actions Researched for Radiation Induced Illness: Mucositis
NameACCKFocus
Laser Treatment: Low-Level443Locked
1 Problematic Actions Researched for Radiation Induced Illness: Mucositis
NameACCKFocus
Radiotherapy110Locked

View the Evidence:
43 Abstracts with Radiation Induced Illness: Mucositis Research

[+]

A systematic review and meta-analysis of the efficacy of low-level laser for treatment of cancer oral mucositis.Feb 06, 2019

Pubmed Data : Lasers Med Sci. 2019 Feb 7. Epub 2019 Feb 7. PMID: 30729351
Article Published Date : Feb 06, 2019
Study Type : Meta Analysis, Review
Additional Links
Diseases : Radiation Induced Illness: Mucositis
Therapeutic Actions : Photobiomodulation
[+]

Honey is a reasonable treatment for radiation-induced mucositis.Mar 28, 2016

Pubmed Data : Head Neck. 2016 Mar 29. Epub 2016 Mar 29. PMID: 27028991
Article Published Date : Mar 28, 2016
Study Type : Meta Analysis
Additional Links
Substances : Honey
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Oral administration of honey after radiotherapy could prevent moderate to severe mucositis and associated weight loss.Mar 15, 2015

Pubmed Data : Laryngoscope. 2015 Mar 16. Epub 2015 Mar 16. PMID: 25778825
Article Published Date : Mar 15, 2015
Study Type : Meta Analysis
Additional Links
Substances : Honey
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
Additional Keywords : Significant Treatment Outcome
[+]

Topical Vitamin E and vitamin A could be benefical against chemo induced oral mucositis.Apr 30, 2017

Pubmed Data : J Clin Diagn Res. 2017 May ;11(5):ZE06-ZE09. Epub 2017 May 1. PMID: 28658926
Article Published Date : Apr 30, 2017
Study Type : Meta Analysis
Additional Links
Substances : Vitamin A, Vitamin E
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Chemoprotective Agents, Radioprotective
[+]

A water based extract of propolis efficiently prevents and heals radiotherapy induced mucositis.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Cancer Prev. 2015 Oct ;8(5):e4019. Epub 2015 Oct 27. PMID: 26634113
Article Published Date : Sep 30, 2015
Study Type : Human Study
Additional Links
Substances : Bee Propolis
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Aloe vera mouthwash was as beneficial as benzydamine mouthwash in alleviating the severity of radiation-induced mucositis.Dec 31, 2014

Pubmed Data : Oral Health Prev Dent. 2015 ;13(4):309-15. PMID: 25431805
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Aloe Vera
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Natural Substances Versus Drugs, Plant Extracts
[+]

An extract of Glycyrrhiza can be effective for decreasing the severity of oral mucositis in head and neck cancer patients undergoing radiotherapy.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dent (Tehran). 2017 Sep ;14(5):267-274. PMID: 29296112
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Substances : Licorice
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

applying natural honey on oral mucositis was effective among head and neck cancers patients receiving external beam radiation therapy.Dec 31, 2015

Pubmed Data : Gulf J Oncolog. 2016 Jan ;1(20):30-7. PMID: 27050177
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Honey
Diseases : Oral Mucositis, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Curcumin mouthwash is well tolerated and effective in controlling the signs and symptoms of Radio-chemotherapy induced oral mucositis.Jul 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Diagn Res. 2015 Aug ;9(8):ZC59-62. Epub 2015 Aug 1. PMID: 26436049
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Radiation Induced Illness: Mucositis, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Chemical: Chlorhexidine, Natural Substances Versus Chemicals, Significant Treatment Outcome
[+]

Epigallocatechin-3-gallate mouthwash protects mucosa from radiation-induced mucositis in head and neck cancer patients.Dec 31, 2019

Pubmed Data : Invest New Drugs. 2020 08 ;38(4):1129-1136. Epub 2019 Nov 7. PMID: 31701429
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Glutamine significantly decreased mucositis severity in the oral cavity, pharynx and larynx induced by chemoradiotherapy.Oct 22, 2014

Pubmed Data : Oncol Rep. 2014 Oct 23. Epub 2014 Oct 23. PMID: 25351453
Article Published Date : Oct 22, 2014
Study Type : Human Study
Additional Links
Substances : Glutamine
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Chemotherapeutic, Radioprotective
[+]

Honey can be used for decreasing pain associated with radiation-induced mucositis in cancer patients.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Palliat Care. 2015 Sep-Dec;21(3):268-73. PMID: 26600693
Article Published Date : Aug 31, 2015
Study Type : Human Study
Additional Links
Substances : Honey
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Analgesics, Radioprotective
[+]

Honey mitigates the radiation-induced mucositis and does not interfere with tumor cell killing.Sep 05, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2017 Sep 6 ;6(9). Epub 2017 Sep 6. PMID: 28878156
Article Published Date : Sep 05, 2017
Study Type : Human Study
Additional Links
Substances : Honey
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Nigella sativa oil mouth rinse improves chemotherapy-induced oral mucositis in patients with acute myeloid leukemia.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:3619357. Epub 2019 Oct 30. PMID: 31781612
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Acute Myeloid Leukemia, Radiation Induced Illness: Mucositis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Radioprotective
[+]

Photobiomodulation reduces the impact of radiotherapy on oral health.Oct 27, 2020

Pubmed Data : Lasers Med Sci. 2020 Oct 28. Epub 2020 Oct 28. PMID: 33113075
Article Published Date : Oct 27, 2020
Study Type : Human Study
Additional Links
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis, Radiotherapy
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Radioprotective
[+]

Photodynamic therapy and low level laser therapy could be used for the treatment of oral mucositis.Nov 21, 2017

Pubmed Data : Photodiagnosis Photodyn Ther. 2017 Nov 22. Epub 2017 Nov 22. PMID: 29175466
Article Published Date : Nov 21, 2017
Study Type : Human Study
Additional Links
Diseases : Radiation Induced Illness: Mucositis
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Radioprotective
[+]

Prophylactic administration of conventional form of silymarin tablets could significantly reduce the severity of radiotherapy induced mucositis.Aug 22, 2016

Pubmed Data : Phytother Res. 2016 Aug 23. Epub 2016 Aug 23. PMID: 27555604
Article Published Date : Aug 22, 2016
Study Type : Human Study
Additional Links
Substances : Silymarin
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Prophylactic Agents, Radioprotective
Additional Keywords : Significant Treatment Outcome
[+]

Protective effect of Punica granatum extract in head and neck cancer patients undergoing radiotherapy.Sep 30, 2019

Pubmed Data : Indian J Otolaryngol Head Neck Surg. 2019 Oct ;71(Suppl 1):318-320. Epub 2018 Mar 15. PMID: 31741979
Article Published Date : Sep 30, 2019
Study Type : Human Study
Additional Links
Substances : Pomegranate
Diseases : Chemotherapy and Radiation Toxicity, Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Salt and soda mouthwashes are as effective as micronized sucralfate in treating radiation-induced mucositis. Jan 01, 2003

Pubmed Data : Cancer Invest. 2003;21(1):21-33. PMID: 12643006
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Substances : Salt, Sodium Bicarbonate
Diseases : Mucositis, Radiation Induced Illness: Mucositis
Additional Keywords : Natural Substances Versus Drugs
[+]

Serum vitamin status could predict the severity of radiation-induced mucositis.Dec 09, 2020

Pubmed Data : Head Neck. 2020 Dec 10. Epub 2020 Dec 10. PMID: 33300654
Article Published Date : Dec 09, 2020
Study Type : Human Study
Additional Links
Substances : Riboflavin (Vitamin B-2), Vitamin C
Diseases : Nasopharyngeal Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

The application of Indian turmeric and honey on treatment-induced oral mucositis was effective.Oct 31, 2014

Pubmed Data : Nurs J India. 2014 Nov-Dec;105(6):258-60. PMID: 26182820
Article Published Date : Oct 31, 2014
Study Type : Human Study
Additional Links
Substances : Honey, Turmeric
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
Additional Keywords : Significant Treatment Outcome
[+]

The Indian Spice Turmeric Delays and Mitigates Radiation-Induced Oral Mucositis in Patients Undergoing Treatment for Head and Neck Cancer: An Investigational Study.Oct 30, 2013

Article Published Date : Oct 30, 2013
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Head and Neck Cancer, Mucositis, Radiation Induced Illness, Radiation Induced Illness: Mucositis, Radiotherapy
Anti Therapeutic Actions : Radiotherapy
[+]

The study provided evidence on the positive effect of thyme honey on the management of radiation-induced oral mucositis.May 31, 2018

Pubmed Data : Eur J Oncol Nurs. 2018 Jun ;34:89-97. Epub 2018 Apr 30. PMID: 29784145
Article Published Date : May 31, 2018
Study Type : Human Study
Additional Links
Substances : Honey, Thyme
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

These results demonstrate that royal jelly administrated by a certain procedure improved the signs and symptoms of oral mucositis.Jun 30, 2014

Pubmed Data : Holist Nurs Pract. 2014 Jul-Aug;28(4):242-6. PMID: 24919094
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Substances : Royal Jelly
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Turmeric can significantly reduce chemoradiotherapy-induced severe oral mucositis, dysphagia, oral pain, and dermatitis in oral cancer patients.Jun 22, 2021

Pubmed Data : ORL J Otorhinolaryngol Relat Spec. 2021 Jun 23:1-11. Epub 2021 Jun 23. PMID: 34161952
Article Published Date : Jun 22, 2021
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Chemoprotective Agents, Radioprotective
[+]

Turmeric extract reduces the incidence and severity of radiation-induced mucositis.Feb 06, 2020

Pubmed Data : J Laryngol Otol. 2020 Feb 7:1-6. Epub 2020 Feb 7. PMID: 32029014
Article Published Date : Feb 06, 2020
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Chemotherapy and Radiation Toxicity, Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Woad (Isatis indigotica) reduces the severity of radiation mucositis, anorexia and swallowing difficulty. Jul 01, 2009

Pubmed Data : J Altern Complement Med. 2009 Jul;15(7):771-8. PMID: 19534614
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Substances : Woad
Diseases : Anorexia, Dysphagia, Mucositis, Radiation Induced Illness, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Zataria mouthwash effectively decreases the severity of oral mucositis and mouth pain in patients with head and neck cancer treated with radiotherapy.Jun 30, 2018

Pubmed Data : Clin Oral Investig. 2018 Jul ;22(6):2263-2272. Epub 2018 Jan 8. PMID: 29313134
Article Published Date : Jun 30, 2018
Study Type : Human Study
Additional Links
Substances : Zataria multiflora
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
Additional Keywords : Plant Extracts
[+]

This case report confirms the effectiveness of photobiomodulation therapy in the management of oral mucositis, dysgeusia, and oral drynessNov 09, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dent J (Basel). 2018 Nov 10 ;6(4). Epub 2018 Nov 10. PMID: 30423851
Article Published Date : Nov 09, 2018
Study Type : Human: Case Report
Additional Links
Diseases : Radiation Induced Illness: Mucositis
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Radioprotective
[+]

Curcumin is effective in the prevention of radiation-induced oral mucositis. Feb 01, 2004

Pubmed Data : Int J Radiat Biol. 2004 Feb;80(2):177-82. PMID: 15164799
Article Published Date : Feb 01, 2004
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Radiation Induced Illness, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Curcumin protects against gamma radiation-induced ileal mucosal damage.Jun 01, 2009

Pubmed Data : Arch Toxicol. 2009 Jun;83(6):609-17. Epub 2008 Aug 27. PMID: 18754102
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Radiation Induced Illness, Radiation Induced Illness: Mucositis
Pharmacological Actions : Antioxidants, Radioprotective
[+]

Dietary pectin is a radioprotective agent; prevents IR-induced deletion of potential reserve ISCs; facilitates crypt regeneration; and ultimately promotes overall survival.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(8):e0135561. Epub 2015 Aug 13. PMID: 26270561
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Pectin
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
Additional Keywords : Intestinal Stem Cells, Significant Treatment Outcome
[+]

Palmitoylethanolamide regulates development of intestinal radiation injury in a mast cell-dependent manner.Oct 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dig Dis Sci. 2014 Nov ;59(11):2693-703. Epub 2014 May 22. PMID: 24848354
Article Published Date : Oct 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Propolis is effective in reducing and delaying radiation-induced mucositis in an animal model.Oct 01, 2005

Pubmed Data : Georgian Med News. 2005 Oct;(127):50-3. PMID: 20563358
Article Published Date : Oct 01, 2005
Study Type : Animal Study
Additional Links
Substances : Bee Propolis
Diseases : Mucositis, Radiation Induced Illness, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Propolis protects against radiation-induced oral mucositis in rats.Jan 01, 2011

Pubmed Data : Kulak Burun Bogaz Ihtis Derg. 2011 Jan-Feb;21(1):32-41. PMID: 21303315
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Bee Propolis
Diseases : Mucositis, Radiation Induced Illness, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Protective effect of lycopene on oral mucositis and antioxidant capacity of blood plasma in the rat exposed to gamma radiation.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Caspian J Intern Med. 2020 ;11(4):419-425. PMID: 33680384
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Antioxidants, Radioprotective
[+]

Topical application of Nigella sativa had beneficial effects on acute radiation-induced nasal mucositis.Jan 18, 2018

Pubmed Data : J Craniofac Surg. 2018 Jan 19. Epub 2018 Jan 19. PMID: 29381633
Article Published Date : Jan 18, 2018
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Vitamin E and Aloe vera helped decrease inflammatory responses and healing of the lesions induced on the tongue of rats subjected to radiation.Dec 22, 2015

Pubmed Data : Support Care Cancer. 2015 Dec 23. Epub 2015 Dec 23. PMID: 26698599
Article Published Date : Dec 22, 2015
Study Type : Animal Study
Additional Links
Substances : Aloe Vera, Vitamin E
Diseases : Inflammation, Radiation Induced Illness: Mucositis, Radiotherapy
Pharmacological Actions : Anti-Inflammatory Agents, Radioprotective
[+]

Vitamin E especially at dose of 500 mg/Kg could be an effective treatment for radiation-induced oral mucositis.Sep 26, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Oral Health. 2023 Sep 27 ;23(1):697. Epub 2023 Sep 27. PMID: 37759230
Article Published Date : Sep 26, 2023
Study Type : Animal Study
Additional Links
Substances : Vitamin E
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Aloe barbadensis can play a significant role in dentistry in treatment of lichen planus, oral submucous fibrosis, recurrent aphthous stomatitis, alveolar osteitis, periodontitis.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Bioallied Sci. 2015 Apr ;7(Suppl 1):S255-9. PMID: 26015726
Article Published Date : Mar 31, 2015
Study Type : Review
Additional Links
Substances : Aloe Vera
Diseases : Gingivitis, Lichen Planus, Oral Submucous Fibrosis, Periodontal Diseases, Radiation Induced Illness: Mucositis, Stomatitis: Aphthous
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Immunomodulatory, Radioprotective
Additional Keywords : Aloe Barbadensis
[+]

Conventional honey is likely to be effective in the prophylaxis and treatment of radiation- and chemoradiation-induced oral mucositis.Jan 31, 2019

Pubmed Data : Complement Ther Clin Pract. 2019 Feb ;34:145-152. Epub 2018 Nov 30. PMID: 30712719
Article Published Date : Jan 31, 2019
Study Type : Review
Additional Links
Substances : Honey
Diseases : Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Most studies showed statistically significant result demonstrating the effectiveness of Aloe vera in treatment of oral diseases.Jul 31, 2016

Pubmed Data : J Clin Diagn Res. 2016 Aug ;10(8):ZE01-7. Epub 2016 Aug 1. PMID: 27656587
Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Aloe Vera
Diseases : Burning Mouth Syndrome, Oral Lichen Planus, Oral Mucositis, Oral Submucous Fibrosis, Radiation Induced Illness: Mucositis
[+]

The application of topical chamomile in the preventive/therapeutic of chemo-induced oral mucositis seems to be recommended.Feb 28, 2022

Pubmed Data : Phytother Res. 2022 Mar ;36(3):1115-1125. Epub 2022 Feb 7. PMID: 35129844
Article Published Date : Feb 28, 2022
Study Type : Review
Additional Links
Substances : Chamomile
Diseases : Oral Mucositis, Radiation Induced Illness: Mucositis
Pharmacological Actions : Chemoprotective Agents, Radioprotective

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The humble spice, in doses available for pennies a day, has been found to reduce one of the most devastating side effects of radiation treatment for head and neck cancer.

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