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23 Substances Researched for Radiotherapy
NameACCKFocus
Vitamin E314Locked
Vitamin A212Locked
Vitamin C212Locked
Hyaluronic Acid110Locked
Turmeric110Locked
Yarrow15Locked
Thymoquinone24Locked
Honey13Locked
Neem13Locked
Aloe Vera12Locked
Apples12Locked
Curcumin12Locked
Fucoidan12Locked
Guduchi 12Locked
Moringa oleifera12Locked
NAC (N-acetyl-L-cysteine)12Locked
Nigella sativa (aka Black Seed)12Locked
Silibinin12Locked
Genistein11Locked
Holy Basil11Locked
Oregano11Locked
Peppermint11Locked
Rosemary11Locked
3 Therapeutic Actions Researched for Radiotherapy
NameACCKFocus
Laser Treatment: Low-Level110Locked
Qigong110Locked
Tai Chi110Locked
2 Problematic Actions Researched for Radiotherapy
NameACCKFocus
Radiotherapy220Locked
Low Dose Ionizing Radiation15Locked

View the Evidence:
38 Abstracts with Radiotherapy Research

[+]

Effectiveness of black mulberry molasses in prevention of radiotherapy-induced oral mucositis.Nov 30, 2017

Pubmed Data : J Altern Complement Med. 2017 Dec ;23(12):971-979. Epub 2017 Jul 5. PMID: 28677999
Article Published Date : Nov 30, 2017
Study Type : Human Study
Additional Links
Substances : Mulberry
Diseases : Oral Mucositis, Radiotherapy
Pharmacological Actions : Radioprotective
Additional Keywords : Plant Extracts
[+]

Efficacy of EGCG in preventing dermatitis in patients with breast cancer receiving postoperative radiotherapy.May 31, 2022

Pubmed Data : JAMA Dermatol. 2022 Jun 1. Epub 2022 Jun 1. PMID: 35648426
Article Published Date : May 31, 2022
Study Type : Human Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Breast Cancer, Dermatitis, Radiotherapy
Pharmacological Actions : Radioprotective
[+]

Hyaluronic acid and vitamins are effective in reducing vaginal atrophy in women receiving radiotherapy.Nov 30, 2015

Pubmed Data : Minerva Ginecol. 2015 Dec ;67(6):523-531. PMID: 26788875
Article Published Date : Nov 30, 2015
Study Type : Human Study
Additional Links
Substances : Hyaluronic Acid, Vitamin A, Vitamin E
Diseases : Radiotherapy, Vaginal Atrophy
Pharmacological Actions : Radioprotective
[+]

Low-level laser therapy in the management of oral mucositis induced by radiotherapy.Dec 31, 2021

Pubmed Data : J Contemp Dent Pract. 2022 Jan 1 ;23(1):31-36. Epub 2022 Jan 1. PMID: 35656654
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Diseases : Head and Neck Cancer, Oral Mucositis, Radiotherapy
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Radioprotective
[+]

Photobiomodulation reduces the impact of radiotherapy on oral health.Oct 27, 2020

Pubmed Data : Lasers Med Sci. 2020 Oct 28. Epub 2020 Oct 28. PMID: 33113075
Article Published Date : Oct 27, 2020
Study Type : Human Study
Additional Links
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis, Radiotherapy
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Radioprotective
[+]

Qigong and Tai chi during radiation for prostate cancer resulted in superior sleep duration midway through radiation.Aug 21, 2016

Pubmed Data : Psychooncology. 2016 Aug 22. Epub 2016 Aug 22. PMID: 27548839
Article Published Date : Aug 21, 2016
Study Type : Human Study
Additional Links
Diseases : Prostate Cancer, Radiotherapy
Therapeutic Actions : Qigong, Tai Chi
[+]

The Indian Spice Turmeric Delays and Mitigates Radiation-Induced Oral Mucositis in Patients Undergoing Treatment for Head and Neck Cancer: An Investigational Study.Oct 30, 2013

Article Published Date : Oct 30, 2013
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Head and Neck Cancer, Mucositis, Radiation Induced Illness, Radiation Induced Illness: Mucositis, Radiotherapy
Anti Therapeutic Actions : Radiotherapy
[+]

There is an increased incidence of myelodysplastic syndrome and acute myeloid leukemia following breast cancer treatment with radiation alone or combined with chemotherapy: a registry cohort analysis 1990-2005.Dec 31, 2010

Pubmed Data : BMC Cancer. 2011 ;11:260. Epub 2011 Jun 21. PMID: 21693006
Article Published Date : Dec 31, 2010
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Chemotherapy and Radiation Toxicity, Leukemia: Acute myelogenous leukemia (AML) , Myelodysplastic Syndromes, Radiotherapy
Anti Therapeutic Actions : Radiotherapy
Adverse Pharmacological Actions : Myelotoxicity, Radiotoxic
[+]

These results indicate that radioprotective effect of vitamin C is preferable to its mitigative effect.Jun 01, 2018

Pubmed Data : Radiat Environ Biophys. 2018 Jun 2. Epub 2018 Jun 2. PMID: 29860661
Article Published Date : Jun 01, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Radiotherapy
Pharmacological Actions : Radioprotective
[+]

Extracts of Yarrow can contribute to reduce genotoxicity induced by ionizing radiation in human lymphocytes.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dose Response. 2015 Jan-Mar;13(1):1559325815583761. Epub 2015 Apr 29. PMID: 26675116
Article Published Date : Dec 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Yarrow
Diseases : Radiotherapy
Pharmacological Actions : Antioxidants, Genoprotective, Radioprotective
Additional Keywords : Dose Response, Plant Extracts
Anti Therapeutic Actions : Low Dose Ionizing Radiation
[+]

Holistic care approach for the effective management of severe radiation dermatitis using neem and honey.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Palliat Care. 2020 Oct-Dec;26(4):540-543. Epub 2020 Nov 19. PMID: 33623321
Article Published Date : Sep 30, 2020
Study Type : Human: Case Report
Additional Links
Substances : Honey, Neem
Diseases : Head and Neck Cancer, Radiotherapy
Pharmacological Actions : Radioprotective
[+]

Administration of moringa leaves extract proved to have a significant effect that can be used to reduce radiation damage.Jun 05, 2018

Pubmed Data : Prog Biophys Mol Biol. 2018 Jun 6. Epub 2018 Jun 6. PMID: 29885347
Article Published Date : Jun 05, 2018
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Radiotherapy
Pharmacological Actions : Radioprotective
[+]

Capsaicin prevents radiotherapy-induced premature ovarian failure in rats.Jan 31, 2022

Pubmed Data : Reprod Fertil Dev. 2022 Feb ;34(3):350-361. PMID: 35101163
Article Published Date : Jan 31, 2022
Study Type : Animal Study
Additional Links
Substances : Capsaicin
Diseases : Oxidative Stress, Radiotherapy
Pharmacological Actions : Anti-Apoptotic, Radioprotective
[+]

Curcumin pre-treatment could reduce the effect of radiation on the skin of patients receiving radiotherapy for the treatment of cancer.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2015 ;4(1):25-41. Epub 2015 Jan 13. PMID: 26785336
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Radiotherapy
Pharmacological Actions : Antioxidants, Radioprotective, Superoxide Dismutase Up-regulation
[+]

Effect of low-dose gamma radiation and lipoic acid on high- radiation-dose induced rat brain injuries.Sep 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dose Response. 2021 Oct-Dec;19(4):15593258211044845. Epub 2021 Nov 5. PMID: 34759786
Article Published Date : Sep 30, 2021
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Radiotherapy
Pharmacological Actions : Neuroprotective Agents, Radioprotective
[+]

Ferulic acid produces neuroprotection against radiation-induced neuroinflammation.Apr 20, 2022

Pubmed Data : Int J Radiat Biol. 2022 Apr 21:1-10. Epub 2022 Apr 21. PMID: 35445640
Article Published Date : Apr 20, 2022
Study Type : Animal Study
Additional Links
Substances : Ferulic acid
Diseases : Brain Inflammation , Radiotherapy
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Fucoidan inhibits radiation-induced pneumonitis and lung fibrosis.Oct 18, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2018 Oct 19 ;16(10). Epub 2018 Oct 19. PMID: 30347679
Article Published Date : Oct 18, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Fibrosis, Pneumonitis, Radiotherapy
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents
[+]

Lonicerae japonicae flos ameliorates radiotherapy-induced mesenteric artery endothelial dysfunction.Jul 19, 2022

Pubmed Data : Phytomedicine. 2022 Jul 20 ;102:154146. Epub 2022 May 11. PMID: 35594639
Article Published Date : Jul 19, 2022
Study Type : Animal Study
Additional Links
Substances : Honeysuckle
Diseases : Endothelial Dysfunction, Radiotherapy
Pharmacological Actions : Radioprotective
Additional Keywords : Plant Extracts
[+]

Nigella sativa oil and Thymoquinone reduce oxidative stress in the brain tissue of rats exposed to full head irradiation.Oct 21, 2019

Pubmed Data : Int J Radiat Biol. 2019 Oct 22:1-28. Epub 2019 Oct 22. PMID: 31638880
Article Published Date : Oct 21, 2019
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed), Thymoquinone
Diseases : Brain: Oxidative Stress, Radiotherapy
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Radioprotective
[+]

Phenolic extracts from the fruits of wild apple could be used as a radioprotector against gamma radiation induced oxidative damage.Jan 06, 2016

Pubmed Data : Food Funct. 2016 Jan 7. Epub 2016 Jan 7. PMID: 26741951
Article Published Date : Jan 06, 2016
Study Type : Animal Study
Additional Links
Substances : Apples
Diseases : Radiotherapy
Pharmacological Actions : Immunomodulatory, Radioprotective
[+]

Silibinin treatment mitigated the radiation-induced lung injury possibly by reducing inflammation and fibrosis, which might be related with the improved survival rate.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Pulm Med. 2015 ;15:68. Epub 2015 Jul 5. PMID: 26143275
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Silibinin
Diseases : Lung Cancer, Radiotherapy
Pharmacological Actions : Chemotherapeutic, Radioprotective
Additional Keywords : Significant Treatment Outcome
[+]

Spirulina could mitigate radiation-induced lung injury moderately.Apr 17, 2022

Pubmed Data : Curr Radiopharm. 2022 Apr 18. Epub 2022 Apr 18. PMID: 35440331
Article Published Date : Apr 17, 2022
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Lung Injury: Acute, Radiotherapy
Pharmacological Actions : Antioxidants, Radioprotective
[+]

The protective effects of apigenin against radiation-induced intestinal injury.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dose Response. 2022 Jul-Sep;20(3):15593258221113791. Epub 2022 Jul 13. PMID: 35859853
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Radiotherapy
Pharmacological Actions : Gastroprotective, Heme oxygenase-1 up-regulation, Nrf2 activation, Radioprotective
[+]

The protective efficacy of hesperidin and thymol on radiation-induced submandibular gland damage.Sep 22, 2022

Pubmed Data : Laryngoscope. 2022 Sep 23. Epub 2022 Sep 23. PMID: 36149936
Article Published Date : Sep 22, 2022
Study Type : Animal Study
Additional Links
Substances : Hesperidin, Thymol
Diseases : Radiotherapy
Pharmacological Actions : Antioxidants, Radioprotective
[+]

The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats.Aug 06, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Aug 7. Epub 2019 Aug 7. PMID: 31392607
Article Published Date : Aug 06, 2019
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Radiotherapy
Pharmacological Actions : Antioxidants, Radioprotective, Renoprotective
[+]

The significant radioprotective effect of vitamin C at doses used in this study opens new horizons in developing non-toxic, cost effective, easily available radioprotectors.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biomed Phys Eng. 2015 Jun ;5(2):59-66. Epub 2015 Jun 1. PMID: 26157731
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Vitamin A, Vitamin C, Vitamin E
Diseases : Radiotherapy
Pharmacological Actions : Radioprotective
Additional Keywords : Supplementation
[+]

Thymoquinone has beneficial effects as an effective radioprotective candidate that enhances cellular immunity.Feb 14, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2016 Feb 15 ;38(2):786-800. Epub 2016 Feb 15. PMID: 26872132
Article Published Date : Feb 14, 2016
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Radiotherapy
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-6 Downregulation, Radioprotective, Radiosensitizer, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tinospora cordifolia root extract administration protects ovaries against radiation exposure.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:346427. Epub 2015 Aug 18. PMID: 26357520
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Guduchi
Diseases : Radiotherapy
Pharmacological Actions : Radioprotective
Additional Keywords : Plant Extracts
[+]

Treatment of radiation-induced brain injury with bisdemethoxycurcumin.Jan 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2023 Feb ;18(2):416-421. PMID: 35900439
Article Published Date : Jan 31, 2023
Study Type : Animal Study
Additional Links
Substances : Bisdemethoxycurcumin
Diseases : Radiotherapy
Pharmacological Actions : Neuroprotective Agents, Radioprotective
[+]

Vitamin E and Aloe vera helped decrease inflammatory responses and healing of the lesions induced on the tongue of rats subjected to radiation.Dec 22, 2015

Pubmed Data : Support Care Cancer. 2015 Dec 23. Epub 2015 Dec 23. PMID: 26698599
Article Published Date : Dec 22, 2015
Study Type : Animal Study
Additional Links
Substances : Aloe Vera, Vitamin E
Diseases : Inflammation, Radiation Induced Illness: Mucositis, Radiotherapy
Pharmacological Actions : Anti-Inflammatory Agents, Radioprotective
[+]

Withania somnifera root extract counteract acute and chronic impact of γ-radiation on liver and spleen of rats.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Hum Exp Toxicol. 2022 Jan-Dec;41:9603271221106344. PMID: 35656930
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Radiotherapy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Radioprotective
Additional Keywords : Plant Extracts
[+]

3,3'-Diindolylmethane attenuates inflammation and fibrosis in radiation-induced lung injury.Dec 31, 2021

Pubmed Data : Exp Lung Res. 2022 04 ;48(3):103-113. Epub 2022 May 20. PMID: 35594367
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Diseases : Fibrosis, Inflammation, Radiotherapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, MicroRNA modulator, NF-kappaB Inhibitor, Transforming growth factor beta (TGF-β) inhibitor
[+]

Caffeic acid phenethyl ester: A review on its pharmacological importance, and its association with free radicals, COVID-19, and radiotherapy.Dec 22, 2022

Pubmed Data : Phytother Res. 2022 Dec 23. Epub 2022 Dec 23. PMID: 36562210
Article Published Date : Dec 22, 2022
Study Type : Review
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Cancers: All, Coronavirus Infection, Radiotherapy
Pharmacological Actions : Antiproliferative , Radioprotective, Radiosensitizer
[+]

Genistein is a potential candidate for adjuvant therapy to alleviate radiation induced injuries to human recipients of ionizing radiation.Jun 17, 2015

Pubmed Data : Cancer Lett. 2015 Jun 18. Epub 2015 Jun 18. PMID: 26095601
Article Published Date : Jun 17, 2015
Study Type : In Vitro Study
Additional Links
Substances : Genistein
Diseases : Radiotherapy
Pharmacological Actions : Radioprotective, Radiosensitizer
[+]

Radioprotective effects of plants from the Lamiaceae family. Oct 28, 2020

Pubmed Data : Anticancer Agents Med Chem. 2020 Oct 29. Epub 2020 Oct 29. PMID: 33121420
Article Published Date : Oct 28, 2020
Study Type : Review
Additional Links
Substances : Holy Basil, Oregano, Peppermint, Rosemary
Diseases : Radiotherapy
Pharmacological Actions : Radioprotective
[+]

Tanshinone IIA accomplished protection against radiation-induced cardiomyocyte injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2022 ;2022:1478181. Epub 2022 Aug 22. PMID: 36046762
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Radiotherapy
Pharmacological Actions : Cardioprotective, Radioprotective
[+]

Ellagic acid enhances the anticancer activity of radiation therapy and protects normal cells against radiation damage.Sep 01, 2005

Pubmed Data : Clin Chim Acta. 2005 Sep;359(1-2):89-100. PMID: 15922998
Article Published Date : Sep 01, 2005
Additional Links
Diseases : Radiotherapy
[+]

Yeast-derived beta-glucan has radioprotective and anti-tumor effects in mice.Jun 01, 2005

Pubmed Data : J Med Food. 2005 Summer;8(2):154-8. PMID: 16117606
Article Published Date : Jun 01, 2005
Additional Links
Diseases : Radiotherapy

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