Renal tubulointerstitial fibrosis

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7 Substances Researched for Renal tubulointerstitial fibrosis

Name	AC	CK
Angelica	1	2
Astragalus	1	2
Mangiferin	1	2
Salacia oblonga	1	2
Chrysin	1	1
Curcumin	1	1
Pterostilbene	1	1

3 Problem Substances Researched for Renal tubulointerstitial fibrosis

Name	AC	CK
Mesalamine	2	6
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	2	6
Fructose	1	2

1 Therapeutic Actions Researched for Renal tubulointerstitial fibrosis

Name	AC	CK	Focus
Ayurvedic Medicine	1	2

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

View the Evidence:
9 Abstracts with Renal tubulointerstitial fibrosis Research

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Acute interstitial nephritis due to mesalazine has been reported.Apr 01, 2005

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Pubmed Data : Nephrology (Carlton). 2005 Apr;10(2):103-5. PMID: 15877665

Article Published Date : Apr 01, 2005

Study Type : Human: Case Report

Additional Links

Diseases : Nephritis, Renal tubulointerstitial fibrosis, Ulcerative Colitis

Problem Substances : Mesalamine, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Adverse Pharmacological Actions : Nephrotoxic

[+]

Mesalamine treatment has been reported to cause end-stage kidney insufficiency.Jan 01, 2010

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Pubmed Data : Ned Tijdschr Geneeskd. 2010;154:A1647. PMID: 20699041

Article Published Date : Jan 01, 2010

Study Type : Human: Case Report

Additional Links

Diseases : Kidney Failure, Kidney Tubular Necrosis: Acute, Nephritis, Renal tubulointerstitial fibrosis, Ulcerative Colitis

Problem Substances : Mesalamine, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Astragalus and Angelica sinensis improves the outcome of rats treating with an Ace inhibitor for renal fibrosis secondary to obstructive uropathy. Dec 03, 2009

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Pubmed Data : Phytother Res. 2009 Dec 3. PMID: 19960445

Article Published Date : Dec 03, 2009

Study Type : Animal Study

Additional Links

Substances : Angelica, Astragalus

Diseases : Kidney Diseases, Obstructive uropathy, Renal tubulointerstitial fibrosis

Additional Keywords : Drug-Plant-Vitamin Synergies

[+]

Bixin can be exploited therapeutically to alleviate renal interstitial fibrosis by targeting STAT6 signaling deactivation.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cell Dev Biol. 2020 ;8:576988. Epub 2020 Nov 17. PMID: 33313043

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Bixin

Diseases : Kidney Fibrosis, Renal tubulointerstitial fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Dietary fructose causes tubulointerstitial injury in the normal rat kidney.Mar 01, 2010

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Pubmed Data : Am J Physiol Renal Physiol. 2010 Mar;298(3):F712-20. Epub 2010 Jan 13. PMID: 20071464

Article Published Date : Mar 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Renal tubulointerstitial fibrosis

Problem Substances : Fructose

Adverse Pharmacological Actions : Nephrotoxic

[+]

The Ayurvedic medicine Salacia oblonga (and the compound mangiferin) attenuates diabetic renal fibrosis in rats.Aug 25, 2009

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Pubmed Data : Evid Based Complement Alternat Med. 2009 Aug 25. Epub 2009 Aug 25. PMID: 19706694

Article Published Date : Aug 25, 2009

Study Type : Animal Study

Additional Links

Substances : Mangiferin, Salacia oblonga

Diseases : Diabetes: Kidney Function , Renal Fibrosis, Renal tubulointerstitial fibrosis

Therapeutic Actions : Ayurvedic Medicine

Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors, Anti-Fibrotic, Renoprotective

[+]

Chrysin inhibits diabetic renal tubulointerstitial fibrosis.Jun 30, 2015

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Pubmed Data : J Mol Med (Berl). 2015 Jul ;93(7):759-72. Epub 2015 Jun 11. PMID: 26062793

Article Published Date : Jun 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Chrysin

Diseases : Diabetic Complications, Diabetic Nephropathy, Renal tubulointerstitial fibrosis

Pharmacological Actions : Renoprotective

[+]

Curcumin is a potential candidate for treatment of tubulointerstitial fibrosis.Jan 01, 2010

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Pubmed Data : Am J Nephrol. 2010;31(4):332-41. Epub 2010 Feb 17. PMID: 20160437

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Renal tubulointerstitial fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Pterostilbene attenuated renal interstitial fibrosis by mediating MMT by regulating transcriptional activity of CXCL10.Dec 31, 2019

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Pubmed Data : Am J Chin Med. 2020 ;48(7):1715-1729. Epub 2020 Nov 5. PMID: 33148003

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Pterostilbene

Diseases : Kidney Fibrosis, Renal tubulointerstitial fibrosis

Pharmacological Actions : Anti-Fibrotic, Renoprotective

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 9 Abstracts with Renal tubulointerstitial fibrosis Research

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Currently Available Sorting Options

Acute interstitial nephritis due to mesalazine has been reported.Apr 01, 2005

Mesalamine treatment has been reported to cause end-stage kidney insufficiency.Jan 01, 2010

Astragalus and Angelica sinensis improves the outcome of rats treating with an Ace inhibitor for renal fibrosis secondary to obstructive uropathy. Dec 03, 2009

Bixin can be exploited therapeutically to alleviate renal interstitial fibrosis by targeting STAT6 signaling deactivation.Dec 31, 2019

Dietary fructose causes tubulointerstitial injury in the normal rat kidney.Mar 01, 2010

The Ayurvedic medicine Salacia oblonga (and the compound mangiferin) attenuates diabetic renal fibrosis in rats.Aug 25, 2009

Chrysin inhibits diabetic renal tubulointerstitial fibrosis.Jun 30, 2015

Curcumin is a potential candidate for treatment of tubulointerstitial fibrosis.Jan 01, 2010

Pterostilbene attenuated renal interstitial fibrosis by mediating MMT by regulating transcriptional activity of CXCL10.Dec 31, 2019

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Renal tubulointerstitial fibrosis

View the Evidence:
9 Abstracts with Renal tubulointerstitial fibrosis Research