Retinal Degeneration: Light-Induced

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19 Substances Researched for Retinal Degeneration: Light-Induced
NameACCKFocus
Astragaloside24Locked
Anthocyanins23Locked
Bilberry23Locked
Resveratrol23Locked
Coconut Oil12Locked
Grape12Locked
Lactobacillus paracasei12Locked
Lutein22Locked
NAC (N-acetyl-L-cysteine)12Locked
Polyphenols22Locked
Sea buckthorn12Locked
Ubiquinol12Locked
Zeaxanthin22Locked
Blueberry11Locked
Glutathione11Locked
Green Tea11Locked
Lingonberry11Locked
Proanthocyanidins11Locked
Vitamin C11Locked
3 Therapeutic Actions Researched for Retinal Degeneration: Light-Induced
NameACCKFocus
Blue Light Blocking38Locked
Laser Treatment: Low-Level12Locked
Amber Lenses11Locked
2 Problematic Actions Researched for Retinal Degeneration: Light-Induced
NameACCKFocus
Blue Light (400−495 nm)1748Locked
LED Lighting24Locked

View the Evidence:
31 Abstracts with Retinal Degeneration: Light-Induced Research

[+]

High-energy blue light from visual display terminals can be a risk factor in the ocular surface damage.Jun 10, 2018

Pubmed Data : Zhonghua Yan Ke Za Zhi. 2018 Jun 11 ;54(6):426-431. PMID: 29895116
Article Published Date : Jun 10, 2018
Study Type : Human Study
Additional Links
Diseases : Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

This brings important concerns with regard to blue-enriched light therapy lamps used to treat SAD symptoms and other disorders.Jan 14, 2011

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jan 15 ;35(1):227-31. Epub 2010 Nov 20. PMID: 21094670
Article Published Date : Jan 14, 2011
Study Type : Human Study
Additional Links
Diseases : Retinal Degeneration: Light-Induced, Seasonal Affective Disorder
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

Filtering blue light reduces light-induced oxidative stress, senescence and accumulation of extracellular matrix proteins in retinal cells.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Exp Ophthalmol. 2012 Jan-Feb;40(1):e87-97. Epub 2011 Aug 18. PMID: 21668780
Article Published Date : Dec 31, 2011
Study Type : Human In Vitro
Additional Links
Diseases : Macular Degeneration, Oxidative Stress, Retinal Degeneration: Light-Induced
Therapeutic Actions : Blue Light Blocking
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

A case report of damage to the macula associated with LED-derived blue laser exposure.Apr 23, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Ophthalmol. 2017 Apr 24 ;17(1):49. Epub 2017 Apr 24. PMID: 28438153
Article Published Date : Apr 23, 2017
Study Type : Human: Case Report
Additional Links
Diseases : Eye Damage, Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

A diet supplemented with grapes rescued retinal structure and function in an oxidative stress-induced mouse model of retinal degeneration.Feb 29, 2016

Pubmed Data : Nutrition. 2016 Mar ;32(3):384-90. Epub 2015 Oct 28. PMID: 26732835
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Grape
Diseases : Oxidative Stress, Retinal Degeneration: Light-Induced, Retinal Diseases
Pharmacological Actions : Antioxidants
[+]

Astragaloside A protects against photoreceptor degeneration.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inflamm Res. 2022 ;15:2995-3020. Epub 2022 May 20. PMID: 35645574
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Photooxidative Stress, Retinal Degeneration: Light-Induced
Pharmacological Actions : Neuroprotective Agents, Photoprotective
[+]

Bilberry anthocyanin extract exhibited protective effects against visible light-induced retinal degeneration. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2015 ;20(12):22395-410. Epub 2015 Dec 14. PMID: 26694327
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Bilberry
Diseases : Retinal Degeneration: Light-Induced, Retinal Diseases
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
[+]

Coconut oil protects against light-induced retina degeneration in male Wistar rats.Oct 04, 2018

Pubmed Data : Pathophysiology. 2018 Oct 5. Epub 2018 Oct 5. PMID: 30309759
Article Published Date : Oct 04, 2018
Study Type : Animal Study
Additional Links
Substances : Coconut Oil
Diseases : Retinal Degeneration: Light-Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidant
[+]

Exposure to excessive blue LED light damages retinal pigment epithelium and photoreceptors of pigmented mice.Jul 20, 2018

Pubmed Data : Exp Eye Res. 2018 Jul 21 ;177:1-11. Epub 2018 Jul 21. PMID: 30040948
Article Published Date : Jul 20, 2018
Study Type : Animal Study
Additional Links
Diseases : Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

N-acetylcysteine protected against blue LED light-induced retinal damage in a dose-dependent manner.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2017 ;40(8):1219-1225. PMID: 28769003
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Oxidative Stress, Retinal Degeneration: Light-Induced
Pharmacological Actions : Antioxidants
Additional Keywords : Dose Response
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

Neuroglobin is a potential biological marker of retinal damage induced by LED light.Jun 12, 2014

Pubmed Data : Neuroscience. 2014 Jun 13 ;270:158-67. Epub 2014 Apr 18. PMID: 24747803
Article Published Date : Jun 12, 2014
Study Type : Animal Study
Additional Links
Diseases : Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm), LED Lighting
[+]

Neuroprotective properties of photobiomodulation in retinal regeneration.Dec 31, 2019

Pubmed Data : J Lasers Med Sci. 2020 ;11(3):280-286. Epub 2020 Jun 21. PMID: 32802288
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Eye Damage, Retinal Degeneration: Light-Induced
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Neuroprotective Agents
[+]

Photoreceptor and vision protective effects of astragaloside IV in mice model with light-evoked retinal damage.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Sep ;153:113404. Epub 2022 Jul 12. PMID: 36076531
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Eye Damage, Retinal Degeneration: Light-Induced
Pharmacological Actions : Neuroprotective Agents
[+]

Proanthocyanidins from sea buckthorn seed mediated a protective effect against light-induced retinal degeneration.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 ;8(5). Epub 2016 May 2. PMID: 27144578
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Sea buckthorn
Diseases : Retinal Degeneration: Light-Induced
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
[+]

Resveratrol prevents light-induced retinal degeneration in mice.Oct 01, 2010

Pubmed Data : Am J Pathol. 2010 Oct;177(4):1725-31. Epub 2010 Aug 13. PMID: 20709795
Article Published Date : Oct 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Photosensitivity Disorders, Retinal Degeneration: Light-Induced, Retinal Diseases
[+]

The blockade of blue plus additional visible wavelengths of light was most effective in protecting the retina from light-induced damage. Jul 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Exp Ophthalmol. 2014 Aug ;42(6):555-63. Epub 2013 Dec 4. PMID: 24304494
Article Published Date : Jul 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Retinal Degeneration: Light-Induced
Therapeutic Actions : Blue Light Blocking
Pharmacological Actions : Anti-Apoptotic
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

The data suggest that the blue component of the white-LED may cause retinal toxicity at occupational domestic illuminance.Dec 16, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuroscience. 2016 Dec 17 ;339:296-307. Epub 2016 Oct 14. PMID: 27751961
Article Published Date : Dec 16, 2016
Study Type : Animal Study
Additional Links
Diseases : Macular Degeneration, Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm), LED Lighting
[+]

These results suggest that L. paracasei KW3110 may have a preventive effect against degrative retinal diseases.Dec 14, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Dec 15 ;10(12). Epub 2018 Dec 15. PMID: 30558320
Article Published Date : Dec 14, 2018
Study Type : Animal Study
Additional Links
Substances : Lactobacillus paracasei
Diseases : Blue Light Toxicity, Inflammation, Macular Degeneration, Retinal Degeneration: Light-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

Ubiquinol promotes retinal ganglion cell survival and blocks the apoptotic pathway in ischemic retinal degeneration.Jan 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Biophys Res Commun. 2018 09 18 ;503(4):2639-2645. Epub 2018 Aug 11. PMID: 30107910
Article Published Date : Jan 17, 2018
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Glaucoma, Retinal Degeneration: Light-Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Visual functional effects of constant blue light in a retinal degenerate rat model.Apr 30, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Photochem Photobiol. 2007 May-Jun;83(3):759-65. PMID: 17115798
Article Published Date : Apr 30, 2007
Study Type : Animal Study
Additional Links
Diseases : Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

"Blueberry anthocyanins: protection against ageing and light-induced damage in retinal pigment epithelial cells."Oct 12, 2011

Pubmed Data : Br J Nutr. 2011 Oct 12:1-12. Epub 2011 Oct 12. PMID: 22018225
Article Published Date : Oct 12, 2011
Study Type : In Vitro Study
Additional Links
Substances : Blueberry
Diseases : Aging, Retinal Degeneration: Light-Induced, Retinal Diseases
[+]

A review of the effects and safety of the blue light on retinal cells.Dec 31, 2014

Pubmed Data : Zhonghua Yan Ke Za Zhi. 2015 Jan ;51(1):65-9. PMID: 25877712
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Diseases : Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

Bilberry and lingonberry containing anthocyanidins, procyanidin, and resveratrol exert protective effects against blue LED light-induced retinal photoreceptor cell damage.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2014 ;14:120. Epub 2014 Apr 2. PMID: 24690313
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins, Bilberry, Lingonberry, Polyphenols, Proanthocyanidins, Resveratrol
Diseases : Retinal Degeneration: Light-Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants, NF-kappaB Inhibitor
Additional Keywords : Light-Emitting Diodes (LEDs), Phytotherapy, Plant Extracts
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

Blue light effect on retinal pigment epithelial cells by display devices.Jan 21, 2017

Pubmed Data : Integr Biol (Camb). 2017 05 22 ;9(5):436-443. PMID: 28386617
Article Published Date : Jan 21, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm)
Adverse Pharmacological Actions : Apoptotic
[+]

Blue light phototoxicity toward human corneal and conjunctival epithelial cells in basal and hyperosmolar conditions.Jul 20, 2018

Pubmed Data : Free Radic Biol Med. 2018 Jul 21 ;126:27-40. Epub 2018 Jul 21. PMID: 30040995
Article Published Date : Jul 20, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Dry Eye Syndromes, Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

Deep yellow lenses may protect retinal photoreceptor cells from blue LED light.Feb 29, 2016

Pubmed Data : J Biomed Opt. 2016 Mar ;21(3):35004. PMID: 27008925
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Retinal Degeneration: Light-Induced
Therapeutic Actions : Amber Lenses, Blue Light Blocking
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

Glutathione improves the antioxidant activity of vitamin C in human lens and retinal epithelial cells.Aug 23, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Eye Res. 2020 Aug 24:1-12. Epub 2020 Aug 24. PMID: 32838548
Article Published Date : Aug 23, 2020
Study Type : In Vitro Study
Additional Links
Substances : Glutathione, Vitamin C
Diseases : Retinal Degeneration: Light-Induced, Retinal Detachment
Pharmacological Actions : Antioxidants
Additional Keywords : Natural Substance Synergy
[+]

Green tea polyphenols attenuate ultraviolet B induced damage to human retinal pigment epithelial cells in vitro.Aug 11, 2010

Pubmed Data : Invest Ophthalmol Vis Sci. 2010 Aug 11. Epub 2010 Aug 11. PMID: 20702817
Article Published Date : Aug 11, 2010
Study Type : In Vitro Study
Additional Links
Substances : Green Tea, Polyphenols
Diseases : Retinal Degeneration: Light-Induced
[+]

Impairment of extramitochondrial oxidative phosphorylation in mouse rod outer segments by blue light irradiation.May 31, 2016

Pubmed Data : Biochimie. 2016 Jun ;125:171-8. Epub 2016 Apr 6. PMID: 27059514
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Oxidative Stress, Retinal Degeneration: Light-Induced
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

The pharmacological effects of lutein and zeaxanthin on visual disorders and cognition diseases.Apr 19, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Apr 20 ;22(4). Epub 2017 Apr 20. PMID: 28425969
Article Published Date : Apr 19, 2017
Study Type : Review
Additional Links
Substances : Lutein, Zeaxanthin
Diseases : Blue Light Toxicity, Cataract, Diabetic Retinopathy, Eye Damage, Macular Degeneration, Retinal Degeneration: Light-Induced, Retinal Detachment, Retinitis Pigmentosa, Uveitis
Pharmacological Actions : Antioxidants
[+]

The Photobiology of lutein and zeaxanthin in the eye.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ophthalmol. 2015 ;2015:687173. Epub 2015 Dec 20. PMID: 26798505
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Lutein, Zeaxanthin
Diseases : Blindness, Retinal Degeneration: Light-Induced, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Photoprotective

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