Sarcopenia

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26 Substances Researched for Sarcopenia
NameACCKFocus
Omega-3 Fatty Acids422Locked
Vitamin D312Locked
Whey212Locked
Polyphenols211Locked
Curcumin110Locked
Ginseng (Korean)110Locked
Magnesium110Locked
Miso 110Locked
Resveratrol110Locked
Rutin110Locked
Vitamin B-12110Locked
Chlorella (Algae)15Locked
Baicalein12Locked
Butyrate12Locked
CLA (Conjugated Linoleic Acid)12Locked
Citrulline12Locked
Ginkgo biloba12Locked
Ginseng (American)12Locked
Lactobacillus paracasei12Locked
Loquat12Locked
NAC (N-acetyl-L-cysteine)12Locked
Oligonol12Locked
Burdock11Locked
Creatine11Locked
Flavonoids11Locked
Taurine11Locked
5 Therapeutic Actions Researched for Sarcopenia
NameACCKFocus
Whole-Body Vibration 330Locked
Exercise312Locked
Electric Stimulation 110Locked
Tai Chi110Locked
Fasting/Caloric Restriction12Locked

View the Evidence:
38 Abstracts with Sarcopenia Research

[+]

A diet with more pro-inflammatory potential was associated with a greater odds of sarcopenia.Nov 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2020 Nov 28 ;19(1):129. Epub 2020 Nov 28. PMID: 33248463
Article Published Date : Nov 27, 2020
Study Type : Human Study
Additional Links
Diseases : Sarcopenia
Additional Keywords : Increased Risk, Inflammatory Diet
[+]

Dietary magnesium may play a role in musculoskeletal health.Oct 29, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Oct 30 ;9(11). Epub 2017 Oct 30. PMID: 29084183
Article Published Date : Oct 29, 2017
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Bone Fractures, Osteoporosis, Sarcopenia
Pharmacological Actions : Osteoprotective
[+]

Greater visceral fat and sarcopenia are associated with vitamin D deficiency. Feb 08, 2012

Pubmed Data : J Am Geriatr Soc. 2012 Feb 8. Epub 2012 Feb 8. PMID: 22316299
Article Published Date : Feb 08, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Abdominal Obesity (Midsection Fat), Sarcopenia, Vitamin D Deficiency
[+]

Habitual miso consumption is associated with a low prevalence of sarcopenia in patients with type 2 diabetes.Dec 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Dec 28 ;13(1). Epub 2020 Dec 28. PMID: 33379405
Article Published Date : Dec 27, 2020
Study Type : Human Study
Additional Links
Substances : Miso
Diseases : Diabetes Mellitus: Type 2, Sarcopenia
Additional Keywords : Risk Reduction
[+]

Low muscle mass in patients undergoing surgery for colorectal cancer was associated with an increased postoperative inflammatory response.Jul 15, 2015

Pubmed Data : Clin Nutr. 2015 Jul 16. Epub 2015 Jul 16. PMID: 26205321
Article Published Date : Jul 15, 2015
Study Type : Human Study
Additional Links
Diseases : Colorectal Cancer, Inflammation, Postoperative Recovery, Sarcopenia
Additional Keywords : Increased Risk
[+]

OLE prevents the loss of muscle mass associated with aging and exerts anti-inflammatory and insulin-sensitizing effects on adipose tissue and skeletal muscle.May 06, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 May 7 ;10(5). Epub 2021 May 7. PMID: 34067004
Article Published Date : May 06, 2021
Study Type : Human Study
Additional Links
Substances : Olive leaf extract
Diseases : Aging, Sarcopenia
Pharmacological Actions : Anti-Inflammatory Agents, Insulin Sensitizers
[+]

Omega-3 fatty acids stimulate muscle protein synthesis in older adults and may be useful for the prevention and treatment of sarcopenia. Feb 01, 2011

Pubmed Data : Am J Clin Nutr. 2011 Feb;93(2):402-12. Epub 2010 Dec 15. PMID: 21159787
Article Published Date : Feb 01, 2011
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Sarcopenia
Pharmacological Actions : Anabolic Agents
[+]

Resveratrol enhances exercise-induced cellular and functional adaptations of skeletal muscle in older men and women.May 12, 2017

Pubmed Data : J Gerontol A Biol Sci Med Sci. 2017 May 13. Epub 2017 May 13. PMID: 28505227
Article Published Date : May 12, 2017
Study Type : Human Study
Additional Links
Substances : Resveratrol
Diseases : Sarcopenia
Therapeutic Actions : Exercise
[+]

Sarcopenia might be related to vitamin B12 deficiency.Aug 31, 2017

Pubmed Data : Exp Gerontol. 2017 Sep ;95:136-140. Epub 2017 May 23. PMID: 28549839
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : Sarcopenia, Vitamin B 12 Deficiency
Additional Keywords : Risk Factors
[+]

Tai Chi and whole-body vibration are effective treatments for improving muscle strength and physical performance in sarcopenic men in advanced old age.Aug 31, 2019

Pubmed Data : Eur J Ageing. 2019 Sep ;16(3):273-282. Epub 2019 Mar 2. PMID: 31543722
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Diseases : Sarcopenia
Therapeutic Actions : Tai Chi, Whole-Body Vibration
[+]

The improvements in knee extension performance found in this study, was maintained for 12 weeks after cessation of WBV training.Aug 30, 2016

Pubmed Data : Geriatr Gerontol Int. 2016 Aug 31. Epub 2016 Aug 31. PMID: 27578535
Article Published Date : Aug 30, 2016
Study Type : Human Study
Additional Links
Diseases : Sarcopenia
Therapeutic Actions : Whole-Body Vibration
[+]

These findings demonstrate that dietary inflammatory potential correlates positively with the risk of sarcopenia.Jan 13, 2020

Pubmed Data : Aging (Albany NY). 2020 12 14 ;13(2):1913-1928. Epub 2020 Dec 14. PMID: 33318308
Article Published Date : Jan 13, 2020
Study Type : Human Study
Additional Links
Diseases : Inflammation, Sarcopenia
Additional Keywords : Anti-inflammatory Dietary Sources, Inflammatory Diet
[+]

Twenty-four week administration of Korean red ginseng in diabetes patients resulted in a significant improvement in follistatin and SHBG levels.May 15, 2020

Pubmed Data : Arch Gerontol Geriatr. 2020 May 16 ;90:104108. Epub 2020 May 16. PMID: 32470863
Article Published Date : May 15, 2020
Study Type : Human Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Diabetes Mellitus: Type 2, Sarcopenia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Whey protein, omega-3 fatty acids and polyphenols with electrical muscle stimulation increases muscle strength in elderly adults with limited mobility.Jun 22, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jun 23 ;12(6). Epub 2020 Jun 23. PMID: 32585837
Article Published Date : Jun 22, 2020
Study Type : Human Study
Additional Links
Substances : Curcumin, Omega-3 Fatty Acids, Polyphenols, Rutin, Whey
Diseases : Sarcopenia
Therapeutic Actions : Electric Stimulation
[+]

Whole-body vibration intervention was beneficial on improving the skeletal muscle mass index, physical fitness, and quality of life of sarcopenic older people.Jan 16, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Geriatr. 2018 01 17 ;18(1):17. Epub 2018 Jan 17. PMID: 29343219
Article Published Date : Jan 16, 2018
Study Type : Human Study
Additional Links
Diseases : Sarcopenia
Therapeutic Actions : Whole-Body Vibration
[+]

Chlorella vulgaris improves the regenerative capacity of young and senescent myoblasts and promotes muscle regeneration.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:3520789. Epub 2019 Jun 4. PMID: 31281573
Article Published Date : Dec 31, 2018
Study Type : Human In Vitro
Additional Links
Substances : Chlorella (Algae)
Diseases : Muscle Damage, Sarcopenia
Pharmacological Actions : Regenerative
Additional Keywords : Muscle Regeneration
[+]

Baicalein has a protective effect of on muscle cells.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Metab. 2016 ;2016:3703216. Epub 2016 Dec 5. PMID: 28050282
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Sarcopenia
Pharmacological Actions : Angiogenesis Inducing Agents
Additional Keywords : Angiogenesis Inducing Agents, Baicalein, Ovariectomy-Induced Changes, Sarcopenia
[+]

Caloric restriction increases the expression of genes involved in energy metabolism and it down-regulates the expression of more than 50 pro-inflammatory genes.Jan 01, 2009

Pubmed Data : Toxicol Pathol. 2009;37(1):47-51. Epub 2008 Dec 15. PMID: 19075044
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Aging, Inflammation, Inflammation: Brain, Sarcopenia
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Citrulline increases protein synthesis and protein content in the muscle in old malnourished rats. Sep 01, 2006

Pubmed Data : Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E582-6. Epub 2006 Apr 11. PMID: 16608884
Article Published Date : Sep 01, 2006
Study Type : Animal Study
Additional Links
Substances : Citrulline
Diseases : Sarcopenia
Additional Keywords : Anabolic, Protein Energ Malnutrition
[+]

Conjugated linoleic acid prevents age-associated skeletal muscle loss (sarcopenia). Jun 12, 2009

Pubmed Data : Biochem Biophys Res Commun. 2009 Jun 12;383(4):513-8. Epub 2009 Apr 22. PMID: 19393220
Article Published Date : Jun 12, 2009
Study Type : Animal Study
Additional Links
Substances : CLA (Conjugated Linoleic Acid)
Diseases : Sarcopenia
[+]

Curcumin attenuates sarcopenia in chronic forced exercise executed aged mice.May 04, 2021

Pubmed Data : J Agric Food Chem. 2021 May 5. Epub 2021 May 5. PMID: 33950680
Article Published Date : May 04, 2021
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Sarcopenia
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
[+]

Ginkgo biloba extract and Wisconsin Ginseng delay sarcopenia in Caenorhabditis elegans (nematode). Dec 01, 2007

Pubmed Data : J Gerontol A Biol Sci Med Sci. 2007 Dec;62(12):1337-45. PMID: 18166683
Article Published Date : Dec 01, 2007
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba, Ginseng (American)
Diseases : Sarcopenia
[+]

Lactobacillus paracasei PS23 extenuated sarcopenia progression during aging.Jan 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2019 Jan 29 ;11(2):756-770. PMID: 30696799
Article Published Date : Jan 28, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus paracasei
Diseases : Sarcopenia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Loquat leaf extract enhances myogenic differentiation, improves muscle function and attenuates muscle loss in aged rats.Aug 31, 2015

Pubmed Data : Int J Mol Med. 2015 Sep ;36(3):792-800. Epub 2015 Jul 15. PMID: 26178971
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Loquat
Diseases : Sarcopenia
[+]

N-acetyl cysteine attenuates the sarcopenia and muscle apoptosis induced by chronic liver disease.Sep 16, 2019

Pubmed Data : Curr Mol Med. 2019 Sep 17. Epub 2019 Sep 17. PMID: 31530262
Article Published Date : Sep 16, 2019
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Liver Disease, Sarcopenia
Pharmacological Actions : Anti-Apoptotic
[+]

Oligonol alleviates sarcopenia by regulation of signalling pathways involved in protein turnover and mitochondrial quality.Dec 31, 2018

Pubmed Data : Mol Nutr Food Res. 2019 05 ;63(10):e1801102. Epub 2019 Feb 28. PMID: 30793867
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Oligonol
Diseases : Sarcopenia
Pharmacological Actions : Anti-Apoptotic
[+]

Soluble whey protein hydrolysate ameliorates muscle atrophy induced by immobilization.Oct 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Nov 1 ;12(11). Epub 2020 Nov 1. PMID: 33139592
Article Published Date : Oct 31, 2020
Study Type : Animal Study
Additional Links
Substances : Whey
Diseases : Muscle Atrophy , Sarcopenia
Additional Keywords : Risk Reduction
[+]

These results suggest chamomile useful for use as a supplement or remedy for muscle wasting, including cachexia and sarcopenia.Jul 09, 2021

Pubmed Data : Am J Chin Med. 2021 Jul 10:1-22. Epub 2021 Jul 10. PMID: 34247561
Article Published Date : Jul 09, 2021
Study Type : Animal Study
Additional Links
Substances : Chamomile
Diseases : Cachexia, Muscle Atrophy , Sarcopenia
[+]

This study is the first to show a beneficial effect of butyrate on muscle mass during aging.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging Cell. 2015 Dec ;14(6):957-70. Epub 2015 Aug 20. PMID: 26290460
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Butyrate
Diseases : Sarcopenia
Pharmacological Actions : Antioxidants, Histone deacetylase inhibitor
[+]

Creatine supplementation may attenuate sarcopenia. Mar 01, 2007

Pubmed Data : J Nutr Health Aging. 2007 Mar-Apr;11(2):185-8. PMID: 17435961
Article Published Date : Mar 01, 2007
Study Type : Commentary
Additional Links
Substances : Creatine
Diseases : Sarcopenia
[+]

Exercise as a therapeutic strategy for sarcopenia in heart failure.Oct 12, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2020 Oct 13 ;9(10). Epub 2020 Oct 13. PMID: 33066240
Article Published Date : Oct 12, 2020
Study Type : Review
Additional Links
Diseases : Heart Failure, Sarcopenia
Therapeutic Actions : Exercise
Pharmacological Actions : Cardioprotective
[+]

Impacts of exercise interventions on different diseases and organ functions in mice.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Sport Health Sci. 2020 Jan ;9(1):53-73. Epub 2019 Jul 13. PMID: 31921481
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Diabetes Mellitus: Type 2, Nonalcoholic fatty liver disease (NAFLD), Obesity, Osteoporosis, Parkinson's Disease, Prediabetes, Sarcopenia
Therapeutic Actions : Exercise
Pharmacological Actions : Neuroprotective Agents, Osteoprotective
Additional Keywords : Anti-Obesity Agents, Risk Reduction
[+]

Older people with vitamin D deficiency might be at risk of sarcopenia.Nov 20, 2019

Pubmed Data : Nutrients. 2019 Nov 21 ;11(12). Epub 2019 Nov 21. PMID: 31766576
Article Published Date : Nov 20, 2019
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Sarcopenia, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Onopordopicrin may be a potential therapeutic molecule to fight against oxidative stress in pathological specific muscle disorders.Mar 01, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Mar 2 ;26(5). Epub 2021 Mar 2. PMID: 33801315
Article Published Date : Mar 01, 2021
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Cachexia, Muscular Dystrophies, Oxidative Stress, Sarcopenia
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Sinensetin regulates age-related sarcopenia in cultured primary thigh and calf muscle cells.Oct 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2019 Oct 28 ;19(1):287. Epub 2019 Oct 28. PMID: 31660942
Article Published Date : Oct 27, 2019
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Aging, Sarcopenia
Additional Keywords : Risk Reduction
[+]

The beneficial effects of taurine to counteract sarcopenia.Nov 21, 2016

Pubmed Data : Curr Protein Pept Sci. 2016 Nov 22. Epub 2016 Nov 22. PMID: 27875962
Article Published Date : Nov 21, 2016
Study Type : Review
Additional Links
Substances : Taurine
Diseases : Sarcopenia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : anti aging, Anti-Inflammatory Agents, Antioxidants, Sarcopenia, Taurine
[+]

The quality of nutrition may help to preserve the capacity for skeletal muscle regeneration with age.Feb 29, 2016

Pubmed Data : Ageing Res Rev. 2016 Mar ;26:22-36. Epub 2015 Dec 9. PMID: 26690801
Article Published Date : Feb 29, 2016
Study Type : Review
Additional Links
Substances : Omega-3 Fatty Acids, Polyphenols, Vitamin D
Diseases : Aging, Sarcopenia
Pharmacological Actions : Regenerative
Additional Keywords : Muscle Regeneration
[+]

This narrative review provides an overview of the current knowledge about omega-3 PUFAs and their role in the prevention and treatment of sarcopenia.Feb 18, 2019

Pubmed Data : Aging Clin Exp Res. 2019 Feb 19. Epub 2019 Feb 19. PMID: 30784011
Article Published Date : Feb 18, 2019
Study Type : Review
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Sarcopenia
Pharmacological Actions : Anabolic Agents

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