Scars

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35 Substances Researched for Scars
NameACCKFocus
Onion220Locked
EGCG (Epigallocatechin gallate)211Locked
Gotu Kola110Locked
Ginsenosides35Locked
Hyperforin15Locked
Flavonoids34Locked
Salvia miltiorrhiza24Locked
Shikonin34Locked
Quercetin23Locked
Arctigenin12Locked
Curcumin22Locked
Honokiol12Locked
Kefir12Locked
Kiwifruit12Locked
Marigold12Locked
Pycnogenol (Pine Bark)12Locked
Spirulina12Locked
Allicin11Locked
Almond11Locked
Apigenin11Locked
Beta-Elemene11Locked
Citrus naringin11Locked
Ellagic Acid11Locked
Emodin11Locked
Glycyrrhiza uralensis11Locked
Lithospermum erythrorhizon11Locked
Naringenin 11Locked
Resveratrol11Locked
Rhubarb11Locked
Saikosaponin11Locked
Sembung Leaf11Locked
St. Johns Wort11Locked
Tanshinone IIA11Locked
Vitamin C11Locked
Yarrow11Locked
6 Therapeutic Actions Researched for Scars
NameACCKFocus
Photobiomodulation18114Locked
Light Therapy: Red Colored220Locked
Light-Emitting Diodes (LEDs) Therapy220Locked
Laser Treatment 211Locked
Hyperbaric Treatment12Locked
Infrared Light11Locked

View the Evidence:
62 Abstracts with Scars Research

[+]

Effect of laser and energy-based device therapies to minimize surgical scar formation.Jan 07, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Derm Venereol. 2024 Jan 8 ;104:adv18477. Epub 2024 Jan 8. PMID: 38189223
Article Published Date : Jan 07, 2024
Study Type : Meta Analysis
Additional Links
Diseases : Scars
Therapeutic Actions : Photobiomodulation
[+]

Both both zonal priming and direct EGCG application in scar therapy has positive effects on scar thickness, erythema, hydration and elasticity.Feb 25, 2019

Pubmed Data : J Invest Dermatol. 2019 Feb 26. Epub 2019 Feb 26. PMID: 30822414
Article Published Date : Feb 25, 2019
Study Type : Human Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Scars, Wound Healing
[+]

Comparison of quality of facial scars after single low-level laser therapy and combined low-level with high-level (PDL 595 nm) laser therapy.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dermatol Ther. 2015 ;28(4):201-9. Epub 2015 Jun 2. PMID: 26031491
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Scars
Therapeutic Actions : Laser Treatment , Photobiomodulation
[+]

Early application of 830-nm LED-based photobiomodulation treatment significantly prevents hypertrophic scar formation.Aug 31, 2022

Pubmed Data : Lasers Med Sci. 2022 Sep 1. Epub 2022 Sep 1. PMID: 36045183
Article Published Date : Aug 31, 2022
Study Type : Human Study
Additional Links
Diseases : Scars
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Analgesics
Additional Keywords : Risk Reduction
[+]

Effectiveness and safety of an overnight patch containing Allium cepa extract and allantoin for post-dermatologic surgery scars.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aesthetic Plast Surg. 2018 Aug ;42(4):1144-1150. Epub 2018 Jun 14. PMID: 29948103
Article Published Date : Jul 31, 2018
Study Type : Human Study
Additional Links
Substances : Onion
Diseases : Scars
Pharmacological Actions : Dermatologic Agents
[+]

Effects of Photobiomodulation and Split-Thickness Skin Grafting in the prognosis of wound healing in children with deep burn ulcers.Jan 31, 2022

Pubmed Data : Photobiomodul Photomed Laser Surg. 2022 Feb ;40(2):148-154. Epub 2022 Jan 4. PMID: 34981954
Article Published Date : Jan 31, 2022
Study Type : Human Study
Additional Links
Diseases : Burns, Scars, Ulcers, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Inhibition of fibroblast proliferation in vitro using red light-emitting diodes.Jul 31, 2013

Pubmed Data : Dermatol Surg. 2013 Aug ;39(8):1167-70. Epub 2013 Apr 16. PMID: 23590233
Article Published Date : Jul 31, 2013
Study Type : Human Study
Additional Links
Diseases : Scars
Therapeutic Actions : Light Therapy: Red Colored, Photobiomodulation
Pharmacological Actions : Antiproliferative
[+]

Laser bio-modulation irradiation therapy demonstrates a potential efficacy in managing the hypertrophic scars after surgical repair of unilateral cleft lip.Dec 31, 2022

Pubmed Data : Cleft Palate Craniofac J. 2023 Jan ;60(1):21-26. Epub 2021 Nov 17. PMID: 34786978
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Diseases : Scars
Therapeutic Actions : Photobiomodulation
[+]

Light emitting diode-red light for reduction of post-surgical scarring.Jun 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biophotonics. 2021 Jul ;14(7):e202100073. Epub 2021 May 4. PMID: 33788987
Article Published Date : Jun 30, 2021
Study Type : Human Study
Additional Links
Diseases : Scars
Therapeutic Actions : Light Therapy: Red Colored
[+]

Light-emitting diode based LLLT treatment suppressed the formation of scars after thyroidectomy.Mar 31, 2016

Pubmed Data : Dermatol Surg. 2016 Apr ;42(4):526-34. PMID: 26981718
Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Diseases : Scars, Wound Healing
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Low level laser therapy--a conservative approach to the burn scar? May 31, 2004

Pubmed Data : Burns. 2004 Jun ;30(4):362-7. PMID: 15145195
Article Published Date : May 31, 2004
Study Type : Human Study
Additional Links
Diseases : Burns, Scars
Therapeutic Actions : Photobiomodulation
[+]

Onion extract gel improves the cosmetic appearance of postsurgical scars. Jun 01, 2008

Pubmed Data : J Cosmet Dermatol. 2008 Jun;7(2):101-4. PMID: 18482012
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Onion
Diseases : Scars
[+]

Photobiomodulation (PBM) is an efficient and safe therapeutic modality for post-burn hypertrophic scars in children.Nov 30, 2018

Pubmed Data : Lasers Med Sci. 2018 Dec ;33(9):1991-1995. Epub 2018 Jul 4. PMID: 29974280
Article Published Date : Nov 30, 2018
Study Type : Human Study
Additional Links
Diseases : Scars
Therapeutic Actions : Photobiomodulation
[+]

Photobiomodulation effect on children's scars.Mar 31, 2018

Pubmed Data : Lasers Med Sci. 2018 Apr ;33(3):497-501. Epub 2017 Nov 24. PMID: 29177979
Article Published Date : Mar 31, 2018
Study Type : Human Study
Additional Links
Diseases : Scars
Therapeutic Actions : Photobiomodulation
[+]

Photobiomodulation therapy for enhanced wound and Scar healing.Aug 12, 2025

Pubmed Data : Lasers Med Sci. 2025 Aug 13 ;40(1):334. Epub 2025 Aug 13. PMID: 40802060
Article Published Date : Aug 12, 2025
Study Type : Human Study
Additional Links
Diseases : Scars, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

The effect of Centella Asiatica cream on scar development in patients who underwent open carpal tunnel release surgery.Mar 11, 2023

Pubmed Data : J Hand Ther. 2023 Mar 12. Epub 2023 Mar 12. PMID: 36918311
Article Published Date : Mar 11, 2023
Study Type : Human Study
Additional Links
Substances : Gotu Kola
Diseases : Carpal Tunnel Syndrome, Scars
[+]

Hyperforin may be rather a potential candidate for treatment of hypertrophic scars.Mar 10, 2017

Pubmed Data : Eur J Pharm Biopharm. 2017 Mar 11. Epub 2017 Mar 11. PMID: 28288835
Article Published Date : Mar 10, 2017
Study Type : Human In Vitro
Additional Links
Substances : Hyperforin
Diseases : Scars, Wound Healing
[+]

Photobiomodulation for modulation of neuropathic pain and improvement of scar tissue.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Scars Burn Heal. 2022 ;8:20595131221134052. Epub 2022 Oct 26. PMID: 36310679
Article Published Date : Dec 31, 2021
Study Type : Human: Case Report
Additional Links
Diseases : Neuropathic Pain, Scars
Therapeutic Actions : Photobiomodulation
Additional Keywords : Medication Reduction
[+]

Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: a case series.Jul 31, 2010

Pubmed Data : Lasers Surg Med. 2010 Aug ;42(6):597-601. PMID: 20662038
Article Published Date : Jul 31, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Scars, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Salvianolic acid B attenuates hypertrophic scar formation.Feb 20, 2023

Pubmed Data : Aesthetic Plast Surg. 2023 Feb 21. Epub 2023 Feb 21. PMID: 36810832
Article Published Date : Feb 20, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Scars
Pharmacological Actions : Antiproliferative
[+]

Arctigenin suppresses fibroblast activity and extracellular matrix deposition in hypertrophic scarring by reducing inflammation and oxidative stress.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2020 Dec ;22(6):4783-4791. Epub 2020 Sep 25. PMID: 33174021
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Scars
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Calendula possesses skin regenerative properties.Oct 01, 2008

Pubmed Data : Neurochem Res. 2008 Oct;33(10):2044-53. Epub 2008 Mar 27. PMID: 7185264
Article Published Date : Oct 01, 2008
Study Type : Animal Study
Additional Links
Substances : Marigold
Diseases : Scars, Wounds and Injuries
Additional Keywords : Epithelialization, Regenerative Substances, Skin Regeneration
[+]

Early kiwifruit dressing improved the histological features of cutaneous wounds.Sep 01, 2021

Pubmed Data : J Wound Care. 2021 Sep 2 ;30(Sup9a):XVi-XVvii. PMID: 34597165
Article Published Date : Sep 01, 2021
Study Type : Animal Study
Additional Links
Substances : Kiwifruit
Diseases : Scars, Wound Healing
Additional Keywords : Risk Reduction
[+]

Ginsenoside Rb1 demonstrated inhibitory effects on hypertrophic scars.Mar 04, 2015

Pubmed Data : Eur J Pharmacol. 2015 Mar 5 ;750:151-9. Epub 2015 Jan 22. PMID: 25620132
Article Published Date : Mar 04, 2015
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Burns, Scars, Wound Healing
[+]

GinsenosideRg3 can be employed as an early intervention and a combining therapeutic aid to reduce inflammation and hypertrophic scar formation.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(12):e113640. Epub 2014 Dec 12. PMID: 25502572
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Scars, Wound Healing
Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors
[+]

Healing potential of Spirulina platensis for skin wounds.Feb 06, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2021 Feb 7 ;137:111349. Epub 2021 Feb 7. PMID: 33567349
Article Published Date : Feb 06, 2021
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Scars, Wound Healing
Pharmacological Actions : Anti-Fibrotic
[+]

Honokiol could be used as a potential agent for treating hypertrophic scar and other fibrotic diseases.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:206. Epub 2017 Apr 19. PMID: 28469575
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Scars
[+]

Hyperbaric oxygen therapy is an effective scar management option.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Med Sci. 2025 ;22(5):1167-1175. Epub 2025 Feb 11. PMID: 40027186
Article Published Date : Dec 31, 2024
Study Type : Animal Study
Additional Links
Diseases : Scars, Wound Healing
Therapeutic Actions : Hyperbaric Treatment
[+]

Kefir contains a carbohydrate fraction with anti-inflammatory and cicatrizing (healing via scar formation) activity. Jun 01, 2008

Pubmed Data : J Med Food. 2008 Jun;11(2):356-61. PMID: 18598180
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Kefir
Diseases : Scars
Additional Keywords : Cicatrization
[+]

Proteomic analysis reveals anti-fibrotic effects of blue light photobiomodulation on fibroblasts.Mar 31, 2020

Pubmed Data : Lasers Surg Med. 2020 Apr ;52(4):358-372. Epub 2019 Jul 18. PMID: 31321797
Article Published Date : Mar 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Keloid, Scars
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Anti-Fibrotic, Antiproliferative , Transforming growth factor beta (TGF-β) inhibitor
[+]

Pycnogenol accelerates wound healing and reduces scar formation.Jul 01, 2004

Pubmed Data : Phytother Res. 2004 Jul;18(7):579-81. PMID: 15305320
Article Published Date : Jul 01, 2004
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Pycnogenol (Pine Bark)
Diseases : Scars, Wound Healing
Additional Keywords : Plant Extracts
[+]

Quercetin reduced the population of macrophages and myofibroblasts and the scar formation in cutaneous wound healing. Jul 16, 2018

Pubmed Data : Pharmacology. 2018 Jul 17 ;102(3-4):142-153. Epub 2018 Jul 17. PMID: 30016781
Article Published Date : Jul 16, 2018
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Scars, Wound Healing
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents
[+]

Regulation of glycolysis and the Warburg effect in wound healing.Sep 02, 2020

Pubmed Data : JCI Insight. 2020 Sep 3 ;5(17). Epub 2020 Sep 3. PMID: 32750036
Article Published Date : Sep 02, 2020
Study Type : Animal Study
Additional Links
Substances : Shikonin
Diseases : Scars, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Warburg Effect
[+]

Achillea biebersteinni may inhibit scar formation.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Genet Genomic Med. 2019 05 ;7(5):e640. Epub 2019 Apr 9. PMID: 30968605
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Yarrow
Diseases : Scars
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts
[+]

Allicin can suppress human epidural scar fibroblasts migration, induce cell apoptosis, and block cell proliferation at S phase and G2 phase.Jan 13, 2020

Pubmed Data : World Neurosurg. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31953094
Article Published Date : Jan 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : Allicin
Diseases : Scars
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Almond oil has a diverse range of potential therapeutic properties. Feb 01, 2010

Pubmed Data : Complement Ther Clin Pract. 2010 Feb;16(1):10-2. Epub 2009 Jul 15. PMID: 20129403
Article Published Date : Feb 01, 2010
Study Type : Commentary
Additional Links
Substances : Almond
Diseases : Eczema, Psoriasis, Scars
[+]

Aloe-emodin inhibits scar tissue fibrosis.Sep 30, 2025

Pubmed Data : Hua Xi Kou Qiang Yi Xue Za Zhi. 2025 Oct 1 ;43(5):636-647. PMID: 41159325
Article Published Date : Sep 30, 2025
Study Type : In Vitro Study
Additional Links
Substances : Emodin
Diseases : Fibrosis, Scars
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Antiproliferative
[+]

An ethyl acetate extract of rhubarb showed anti-proliferative activity on hypertrophic scar fibroblasts.Nov 30, 2012

Pubmed Data : Yao Xue Xue Bao. 2012 Dec ;47(12):1618-22. PMID: 23460967
Article Published Date : Nov 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Rhubarb
Diseases : Scars
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Ascorbic acid is potentially capable of minimizing excessive scar formation and promoting a more regenerative healing response.Mar 04, 2019

Pubmed Data : Lab Invest. 2019 Mar 5. Epub 2019 Mar 5. PMID: 30837678
Article Published Date : Mar 04, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C
Diseases : Scars, Wound Healing
[+]

Bioflavonoid galangin suppresses hypertrophic scar formation by the TGF- β/Smad signaling pathway.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:2444839. Epub 2021 Sep 4. PMID: 34518767
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Scars
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor
[+]

Curcumin may have a role to play in modulating pathological scar formation. Apr 01, 2009

Pubmed Data : J Cell Mol Med. 2009 Apr;13(4):712-25. Epub 2008 Apr 10. PMID: 18410527
Article Published Date : Apr 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Scars, Wound Healing
Pharmacological Actions : Antioxidants, Apoptotic
[+]

Curcumin may have a therapeutic role in hyperplastic scars.Dec 01, 2009

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Dec;29(12):1100-3. PMID: 20214332
Article Published Date : Dec 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Scars, Scars: Hyperplastic
[+]

Ellagic acid inhibits the formation of hypertrophic scars.Jun 28, 2023

Pubmed Data : Chem Biol Drug Des. 2023 Jun 29. Epub 2023 Jun 29. PMID: 37386691
Article Published Date : Jun 28, 2023
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid
Diseases : Scars
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor
[+]

Galangin inhibits hypertrophic scar formation via ALK5/Smad2/3 signaling pathway.Jan 31, 2016

Pubmed Data : Mol Cell Biochem. 2016 Feb ;413(1-2):109-18. Epub 2016 Jan 4. PMID: 26728998
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Scars
Pharmacological Actions : Antiproliferative
[+]

Glycyrrhiza soluble polysaccharide combined with microcapsules could accelerate wound healing and promote neovascularization.Jul 31, 2020

Pubmed Data : Int J Biol Macromol. 2020 Aug 1 ;156:906-917. Epub 2020 Mar 28. PMID: 32234447
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Glycyrrhiza uralensis
Diseases : Scars, Wound Healing
Pharmacological Actions : STAT3 Activation
Additional Keywords : Polysaccharides
[+]

H. perforatum root cultures could be a novel lead system for the treatment of hypertrophic scars.Dec 03, 2018

Pubmed Data : Planta Med. 2018 Dec 4. Epub 2018 Dec 4. PMID: 30513539
Article Published Date : Dec 03, 2018
Study Type : In Vitro Study
Additional Links
Substances : St. Johns Wort
Diseases : Scars
Pharmacological Actions : Antiproliferative
[+]

Inhibition of fibroblast proliferation in vitro using low-level infrared light-emitting diodes.Feb 28, 2013

Pubmed Data : Dermatol Surg. 2013 Mar ;39(3 Pt 1):422-5. Epub 2012 Dec 26. PMID: 23279196
Article Published Date : Feb 28, 2013
Study Type : In Vitro Study
Additional Links
Diseases : Scars
Therapeutic Actions : Infrared Light, Photobiomodulation
Pharmacological Actions : Antiproliferative
[+]

Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring.Feb 28, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Semin Cutan Med Surg. 2013 Mar ;32(1):41-52. PMID: 24049929
Article Published Date : Feb 28, 2013
Study Type : Review
Additional Links
Diseases : Autoimmune Disease, Burns, Inflammation, Psoriasis, Scars, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Naringin suppresses the growth and motility of hypertrophic scar fibroblasts.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:1291-1298. Epub 2018 Jun 23. PMID: 30021366
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Scars, Wound Healing
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

PBMT using CO2 lasers contribute to the suppression of scarring in the tissue repair process, leading to favorable esthetic and functional outcomes of wound healing.Nov 27, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diseases. 2023 Nov 28 ;11(4). Epub 2023 Nov 28. PMID: 38131978
Article Published Date : Nov 27, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Scars, Wound Healing
Therapeutic Actions : Laser Treatment , Photobiomodulation
[+]

Photobiomodulation CME part II: Clinical applications in dermatology.Jan 31, 2024

Pubmed Data : J Am Acad Dermatol. 2024 Feb 1. Epub 2024 Feb 1. PMID: 38307144
Article Published Date : Jan 31, 2024
Study Type : Review
Additional Links
Diseases : Acne, Alopecia, Scars, Ulcers, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Preparation of compound Salvia miltiorrhiza- Blumea balsamifera nanoemulsion gel and its effect on hypertrophic scars.May 05, 2024

Pubmed Data : Mol Pharm. 2024 May 6 ;21(5):2298-2314. Epub 2024 Mar 25. PMID: 38527915
Article Published Date : May 05, 2024
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza, Sembung Leaf
Diseases : Scars
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor
[+]

Saikosaponin a increases interleukin-10 expression and inhibits scar formation after sciatic nerve injury.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2018 Sep ;13(9):1650-1656. PMID: 30127128
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Saikosaponin
Diseases : Scars, Sciatic Nerve Crush Injury
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Shikonin induces apoptosis and decreases collagen production in scar-associated fibroblasts and may therefore hold potential as a novel scar remediation therapy.Feb 24, 2015

Pubmed Data : Chem Biol Interact. 2015 Feb 25 ;228:18-27. Epub 2015 Jan 12. PMID: 25591861
Article Published Date : Feb 24, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lithospermum erythrorhizon, Shikonin
Diseases : Burns, Burns: Severe, Scars, Wound Healing
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Shikonin promotes hypertrophic scar repair by autophagy of hypertrophic scar-derived fibroblasts.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Cir Bras. 2023 ;38:e384623. Epub 2023 Oct 23. PMID: 37878984
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Scars
[+]

Tanshinone IIA down-regulated p-Smad3 signaling to inhibit TGF-β1-mediated fibroblast proliferation.Oct 09, 2020

Pubmed Data : Int J Biochem Cell Biol. 2020 Oct 10:105863. Epub 2020 Oct 10. PMID: 33049375
Article Published Date : Oct 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Scars
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor
[+]

The use of low-level energy laser radiation in basic and clinical research. Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Clin Exp Med. 2014 ;23(5):835-842. PMID: 25491701
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Scars, Ulcers, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

These results suggested that naringenin may serve as a novel agent for treatment of hypertrophic scars.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 Oct ;16(4):4643-4649. Epub 2017 Aug 10. PMID: 28849050
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Naringenin
Diseases : Scars
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

This review discusses a number of potential treatments that may reduce or even prevent scarring particularly hypertrophic scarring.Dec 31, 2015

Pubmed Data : Burns Trauma. 2016 ;4:15. Epub 2016 May 4. PMID: 27574685
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : EGCG (Epigallocatechin gallate), Quercetin, Resveratrol
Diseases : Burns, Scars
[+]

This study provides sufficient in vitro evidences for Rg3 as a promising drug in the treatment of human hypertrophic scar.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2018 Mar ;21(3):309-317. PMID: 29511498
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Scars, Scars: Hyperplastic
[+]

This suggests apigenin could potentially provide a new option for the treatment of hypertrophic scars.Jun 04, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2019 Jun 5 ;11(11):3668-3678. PMID: 31170089
Article Published Date : Jun 04, 2019
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Scars
[+]

β-Elemene induces apoptosis by activating the P53 pathway in human hypertrophic scar fibroblasts.Mar 15, 2022

Pubmed Data : IUBMB Life. 2022 Mar 16. Epub 2022 Mar 16. PMID: 35294085
Article Published Date : Mar 15, 2022
Study Type : In Vitro Study
Additional Links
Substances : Beta-Elemene
Diseases : Scars
Pharmacological Actions : Apoptotic

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